Richard E. Straub - Publications

Affiliations: 
National Institute of Mental Health, Bethesda, MD, United States 
Area:
schizophrenia, molecular genetics

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhou J, Luo C, Liu H, Heffel MG, Straub RE, Kleinman JE, Hyde TM, Ecker JR, Weinberger DR, Han S. scMeFormer: a transformer-based deep learning model for imputing DNA methylation states in single cells enhances the detection of epigenetic alterations in schizophrenia. Biorxiv : the Preprint Server For Biology. PMID 38328094 DOI: 10.1101/2024.01.25.577200  0.435
2022 Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, ... ... Straub RE, ... ... Straub R, et al. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science (New York, N.Y.). 377: 511-517. PMID 35901164 DOI: 10.1126/science.abm6222  0.383
2022 Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, ... ... Straub RE, et al. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. PMID 35396580 DOI: 10.1038/s41586-022-04434-5  0.637
2022 Page SC, Sripathy SR, Farinelli F, Ye Z, Wang Y, Hiler DJ, Pattie EA, Nguyen CV, Tippani M, Moses RL, Chen HY, Tran MN, Eagles NJ, Stolz JM, Catallini JL, ... ... Straub RE, et al. Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35017298 DOI: 10.1073/pnas.2109395119  0.418
2021 Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, ... ... Straub RE, et al. Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34035472 DOI: 10.1038/s41386-021-01023-4  0.404
2021 Wang Y, Bae T, Thorpe J, Sherman MA, Jones AG, Cho S, Daily K, Dou Y, Ganz J, Galor A, Lobon I, Pattni R, Rosenbluh C, Tomasi S, Tomasini L, ... ... Straub RE, et al. Comprehensive identification of somatic nucleotide variants in human brain tissue. Genome Biology. 22: 92. PMID 33781308 DOI: 10.1186/s13059-021-02285-3  0.305
2021 Peterson RE, Bigdeli TB, Ripke S, Bacanu SA, Gejman PV, Levinson DF, Li QS, Rujescu D, Rietschel M, Weinberger DR, Straub RE, Walters JTR, Owen MJ, O'Donovan MC, Mowry BJ, et al. Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium. Journal of Psychiatric Research. 137: 215-224. PMID 33691233 DOI: 10.1016/j.jpsychires.2021.02.027  0.551
2019 Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, ... ... Straub RE, et al. Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. American Journal of Human Genetics. 105: 334-350. PMID 31374203 DOI: 10.1016/J.Ajhg.2019.06.012  0.538
2019 Ni P, Noh H, Park GH, Shao Z, Guan Y, Park JM, Yu S, Park JS, Coyle JT, Weinberger DR, Straub RE, Cohen BM, McPhie DL, Yin C, Huang W, et al. Correction: iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function. Molecular Psychiatry. PMID 31366918 DOI: 10.1038/s41380-019-0467-4  0.439
2019 Collado-Torres L, Burke EE, Peterson A, Shin J, Straub RE, Rajpurohit A, Semick SA, Ulrich WS, Price AJ, Valencia C, Tao R, Deep-Soboslay A, Hyde TM, Kleinman JE, et al. Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia. Neuron. PMID 31174959 DOI: 10.1016/J.Neuron.2019.05.013  0.634
2019 Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, ... ... Straub RE, et al. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 10: 2068. PMID 31043617 DOI: 10.1038/S41467-019-10160-W  0.431
2019 Ni P, Noh H, Park GH, Shao Z, Guan Y, Park JM, Yu S, Park JS, Coyle JT, Weinberger DR, Straub RE, Cohen BM, McPhie DL, Yin C, Huang W, et al. iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function. Molecular Psychiatry. PMID 31019265 DOI: 10.1038/S41380-019-0423-3  0.537
2019 Shao Z, Noh H, Bin Kim W, Ni P, Nguyen C, Cote SE, Noyes E, Zhao J, Parsons T, Park JM, Zheng K, Park JJ, Coyle JT, Weinberger DR, Straub RE, et al. Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nature Neuroscience. PMID 30664768 DOI: 10.1038/S41593-018-0313-Z  0.576
2019 Ma L, Semick SA, Chen Q, Li C, Tao R, Price AJ, Shin JH, Jia Y, Brandon NJ, Cross AJ, Hyde TM, Kleinman JE, Jaffe AE, Weinberger DR, ... Straub RE, et al. Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19). Molecular Psychiatry. PMID 30635639 DOI: 10.1038/S41380-018-0293-0  0.502
2018 Toulopoulou T, Zhang X, Cherny S, Dickinson D, Berman KF, Straub RE, Sham P, Weinberger DR. Polygenic risk score increases schizophrenia liability through cognition-relevant pathways. Brain : a Journal of Neurology. PMID 30535067 DOI: 10.1093/Brain/Awy279  0.588
2018 Radulescu E, Jaffe AE, Straub RE, Chen Q, Shin JH, Hyde TM, Kleinman JE, Weinberger DR. Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain. Molecular Psychiatry. PMID 30478419 DOI: 10.1038/S41380-018-0304-1  0.52
2018 Scheggia D, Mastrogiacomo R, Mereu M, Sannino S, Straub RE, Armando M, Managò F, Guadagna S, Piras F, Zhang F, Kleinman JE, Hyde TM, Kaalund SS, Pontillo M, Orso G, et al. Publisher Correction: Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment. Nature Communications. 9: 3560. PMID 30158661 DOI: 10.1038/S41467-018-06062-Y  0.385
2018 Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A, et al. Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis. Nature Neuroscience. 21: 1117-1125. PMID 30050107 DOI: 10.1038/S41593-018-0197-Y  0.623
2018 Lam M, Trampush JW, Yu J, Knowles E, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, ... ... Straub RE, et al. Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018). Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 1-4. PMID 30001766 DOI: 10.1017/Thg.2018.46  0.368
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, ... ... Straub RE, et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. PMID 29942086 DOI: 10.1038/S41588-018-0152-6  0.615
2018 Scheggia D, Mastrogiacomo R, Mereu M, Sannino S, Straub RE, Armando M, Managò F, Guadagna S, Piras F, Zhang F, Kleinman JE, Hyde TM, Kaalund SS, Pontillo M, Orso G, et al. Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment. Nature Communications. 9: 2265. PMID 29891954 DOI: 10.1038/S41467-018-04711-W  0.562
2018 Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, ... ... Straub RE, et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 9: 2098. PMID 29844566 DOI: 10.1038/S41467-018-04362-X  0.498
2018 Ursini G, Punzi G, Chen Q, Marenco S, Robinson JF, Porcelli A, Hamilton EG, Mitjans M, Maddalena G, Begemann M, Seidel J, Yanamori H, Jaffe AE, Berman KF, Egan MF, ... Straub RE, et al. Convergence of placenta biology and genetic risk for schizophrenia. Nature Medicine. PMID 29808008 DOI: 10.1038/S41591-018-0021-Y  0.616
2018 Chen Q, Ursini G, Romer AL, Knodt AR, Mezeivtch K, Xiao E, Pergola G, Blasi G, Straub RE, Callicott JH, Berman KF, Hariri AR, Bertolino A, Mattay VS, Weinberger DR. Schizophrenia polygenic risk score predicts mnemonic hippocampal activity. Brain : a Journal of Neurology. PMID 29415119 DOI: 10.1093/brain/awy004  0.716
2017 Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, ... ... Straub RE, et al. Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. Cell Reports. 21: 2597-2613. PMID 29186694 DOI: 10.1016/J.Celrep.2017.11.028  0.425
2017 Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, ... ... Straub RE, et al. GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Molecular Psychiatry. 22: 1651-1652. PMID 29068436 DOI: 10.1038/Mp.2017.197  0.461
2017 Jaffe AE, Tao R, Norris AL, Kealhofer M, Nellore A, Shin JH, Kim D, Jia Y, Hyde TM, Kleinman JE, Straub RE, Leek JT, Weinberger DR. qSVA framework for RNA quality correction in differential expression analysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28634288 DOI: 10.1073/Pnas.1617384114  0.416
2017 McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, ... ... Straub RE, et al. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356. PMID 28450582 DOI: 10.1126/Science.Aal1641  0.364
2017 Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, ... ... Straub RE, et al. GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Molecular Psychiatry. PMID 28093568 DOI: 10.1038/Mp.2016.244  0.475
2017 Ursini G, Punzi G, Chen Q, Marenco S, Jaffe A, Straub R, Berman K, Hashimoto R, Colantuoni C, Blasi G, Annamaria P, Giancarlo M, Joshua R, Emily H, Allessandro B, et al. 115.1 Placental Gene Expression Mediates the Interaction Between Obstetrical History and Genetic Risk for Schizophrenia Schizophrenia Bulletin. 43: S60-S60. DOI: 10.1093/Schbul/Sbx021.158  0.543
2016 Li M, Jaffe AE, Straub RE, Tao R, Shin JH, Wang Y, Chen Q, Li C, Jia Y, Ohi K, Maher BJ, Brandon NJ, Cross A, Chenoweth JG, Hoeppner DJ, et al. A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus. Nature Medicine. PMID 27158905 DOI: 10.1038/Nm.4096  0.629
2016 Ruble CL, Smith RM, Calley J, Munsie L, Airey DC, Gao Y, Shin JH, Hyde TM, Straub RE, Weinberger DR, Nisenbaum LK. Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons. Bmc Genetics. 17: 16. PMID 26738766 DOI: 10.1186/S12863-015-0325-6  0.428
2015 Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe'er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, ... ... Straub RE, et al. Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 363-73. PMID 25951819 DOI: 10.1002/Ajmg.B.32319  0.422
2015 Schubert CR, O'Donnell P, Quan J, Wendland JR, Xi HS, Winslow AR, Domenici E, Essioux L, Kam-Thong T, Airey DC, Calley JN, Collier DA, Wang H, Eastwood B, Ebert P, ... ... Straub RE, et al. BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders Neuron. 88: 1078-1083. DOI: 10.1016/J.Neuron.2015.10.047  0.446
2014 Dickinson D, Straub RE, Trampush JW, Gao Y, Feng N, Xie B, Shin JH, Lim HK, Ursini G, Bigos KL, Kolachana B, Hashimoto R, Takeda M, Baum GL, Rujescu D, et al. Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals. Jama Psychiatry. 71: 647-56. PMID 24718902 DOI: 10.1001/Jamapsychiatry.2014.157  0.758
2014 Morita Y, Callicott JH, Testa LR, Mighdoll MI, Dickinson D, Chen Q, Tao R, Lipska BK, Kolachana B, Law AJ, Ye T, Straub RE, Weinberger DR, Kleinman JE, Hyde TM. Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4929-40. PMID 24695712 DOI: 10.1523/Jneurosci.1423-13.2014  0.735
2014 Todarello G, Feng N, Kolachana BS, Li C, Vakkalanka R, Bertolino A, Weinberger DR, Straub RE. Incomplete penetrance of NRXN1 deletions in families with schizophrenia. Schizophrenia Research. 155: 1-7. PMID 24680031 DOI: 10.1016/j.schres.2014.02.023  0.582
2014 Jaffe AE, Eaton WW, Straub RE, Marenco S, Weinberger DR. Paternal age, de novo mutations and schizophrenia. Molecular Psychiatry. 19: 274-5. PMID 23752248 DOI: 10.1038/Mp.2013.76  0.545
2013 Stefanis NC, Hatzimanolis A, Avramopoulos D, Smyrnis N, Evdokimidis I, Stefanis CN, Weinberger DR, Straub RE. Variation in psychosis gene ZNF804A is associated with a refined schizotypy phenotype but not neurocognitive performance in a large young male population. Schizophrenia Bulletin. 39: 1252-60. PMID 23155182 DOI: 10.1093/schbul/sbs110  0.647
2013 Radulescu E, Sambataro F, Mattay VS, Callicott JH, Straub RE, Matsumoto M, Weinberger DR, Marenco S. Effect of schizophrenia risk-associated alleles in SREB2 (GPR85) on functional MRI phenotypes in healthy volunteers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 341-9. PMID 22968816 DOI: 10.1038/npp.2012.184  0.714
2013 Stefanis NC, Hatzimanolis A, Smyrnis N, Avramopoulos D, Evdokimidis I, van Os J, Stefanis CN, Straub RE, Weinberger DR. Schizophrenia candidate gene ERBB4: covert routes of vulnerability to psychosis detected at the population level. Schizophrenia Bulletin. 39: 349-57. PMID 22115776 DOI: 10.1093/schbul/sbr169  0.634
2012 Ye T, Lipska BK, Tao R, Hyde TM, Wang L, Li C, Choi KH, Straub RE, Kleinman JE, Weinberger DR. Analysis of copy number variations in brain DNA from patients with schizophrenia and other psychiatric disorders. Biological Psychiatry. 72: 651-4. PMID 22795968 DOI: 10.1016/j.biopsych.2012.06.014  0.565
2012 Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F, Straub RE, Huang W, Thomas CJ, Vakkalanka R, Besterman AD, Lipska BK, Hyde TM, Harrison PJ, Kleinman JE, et al. Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy. Proceedings of the National Academy of Sciences of the United States of America. 109: 12165-70. PMID 22689948 DOI: 10.1073/Pnas.1206118109  0.636
2011 Hyde TM, Lipska BK, Ali T, Mathew SV, Law AJ, Metitiri OE, Straub RE, Ye T, Colantuoni C, Herman MM, Bigelow LB, Weinberger DR, Kleinman JE. Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11088-95. PMID 21795557 DOI: 10.1523/Jneurosci.1234-11.2011  0.59
2011 Zhang F, Chen Q, Ye T, Lipska BK, Straub RE, Vakkalanka R, Rujescu D, St Clair D, Hyde TM, Bigelow L, Kleinman JE, Weinberger DR. Evidence of sex-modulated association of ZNF804A with schizophrenia. Biological Psychiatry. 69: 914-7. PMID 21349497 DOI: 10.1016/j.biopsych.2011.01.003  0.624
2011 Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, ... ... Straub RE, et al. GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. Molecular Psychiatry. 16: 1117-29. PMID 20838396 DOI: 10.1038/Mp.2010.96  0.678
2010 Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, et al. Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. Archives of General Psychiatry. 67: 991-1001. PMID 20921115 DOI: 10.1001/Archgenpsychiatry.2010.117  0.749
2010 Bigos KL, Mattay VS, Callicott JH, Straub RE, Vakkalanka R, Kolachana B, Hyde TM, Lipska BK, Kleinman JE, Weinberger DR. Genetic variation in CACNA1C affects brain circuitries related to mental illness. Archives of General Psychiatry. 67: 939-45. PMID 20819988 DOI: 10.1001/archgenpsychiatry.2010.96  0.76
2010 Lemaitre H, Mattay VS, Sambataro F, Verchinski B, Straub RE, Callicott JH, Kittappa R, Hyde TM, Lipska BK, Kleinman JE, McKay R, Weinberger DR. Genetic variation in FGF20 modulates hippocampal biology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5992-7. PMID 20427658 DOI: 10.1523/JNEUROSCI.5773-09.2010  0.677
2010 Marenco S, Savostyanova AA, van der Veen JW, Geramita M, Stern A, Barnett AS, Kolachana B, Radulescu E, Zhang F, Callicott JH, Straub RE, Shen J, Weinberger DR. Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1708-17. PMID 20357758 DOI: 10.1038/npp.2010.35  0.695
2010 Momeni P, DeTucci K, Straub RE, Weinberger DR, Davies P, Grafman J, Hardy J, Huey ED. Progranulin (GRN) in two siblings of a Latino family and in other patients with schizophrenia. Neurocase. 16: 273-9. PMID 20087814 DOI: 10.1080/13554790903456209  0.553
2010 Weinberger DR, Savostyanova AA, Geramita M, Stern A, Callicott JH, Shen J, Straub RE, Genes SM. GENETIC REGULATION OF GABA ACTIVITY AND RISK FOR SCHIZOPHRENIA Schizophrenia Research. 117: 157. DOI: 10.1016/j.schres.2010.02.161  0.687
2009 Nicodemus KK, Law AJ, Luna A, Vakkalanka R, Straub RE, Kleinman JE, Weinberger DR. A 5' promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression. Molecular Psychiatry. 14: 741-3. PMID 19626024 DOI: 10.1038/Mp.2008.150  0.657
2008 Kempf L, Nicodemus KK, Kolachana B, Vakkalanka R, Verchinski BA, Egan MF, Straub RE, Mattay VA, Callicott JH, Weinberger DR, Meyer-Lindenberg A. Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function. Plos Genetics. 4: e1000252. PMID 18989458 DOI: 10.1371/journal.pgen.1000252  0.752
2008 Tan HY, Nicodemus KK, Chen Q, Li Z, Brooke JK, Honea R, Kolachana BS, Straub RE, Meyer-Lindenberg A, Sei Y, Mattay VS, Callicott JH, Weinberger DR. Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans. The Journal of Clinical Investigation. 118: 2200-8. PMID 18497887 DOI: 10.1172/JCI34725  0.784
2008 Weickert CS, Miranda-Angulo AL, Wong J, Perlman WR, Ward SE, Radhakrishna V, Straub RE, Weinberger DR, Kleinman JE. Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia. Human Molecular Genetics. 17: 2293-309. PMID 18424448 DOI: 10.1093/Hmg/Ddn130  0.648
2008 Matsumoto M, Straub RE, Marenco S, Nicodemus KK, Matsumoto S, Fujikawa A, Miyoshi S, Shobo M, Takahashi S, Yarimizu J, Yuri M, Hiramoto M, Morita S, Yokota H, Sasayama T, et al. The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 105: 6133-8. PMID 18413613 DOI: 10.1073/pnas.0710717105  0.78
2008 Fanous AH, Neale MC, Webb BT, Straub RE, O'Neill FA, Walsh D, Riley BP, Kendler KS. Novel linkage to chromosome 20p using latent classes of psychotic illness in 270 Irish high-density families. Biological Psychiatry. 64: 121-7. PMID 18255048 DOI: 10.1016/J.Biopsych.2007.11.023  0.504
2008 Nicodemus KK, Marenco S, Batten AJ, Vakkalanka R, Egan MF, Straub RE, Weinberger DR. Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk. Molecular Psychiatry. 13: 873-7. PMID 18195713 DOI: 10.1038/sj.mp.4002153  0.624
2008 Goldberg TE, Iudicello J, Russo C, Elvevåg B, Straub R, Egan MF, Weinberger DR. BDNF Val66Met polymorphism significantly affects d' in verbal recognition memory at short and long delays. Biological Psychology. 77: 20-4. PMID 17988784 DOI: 10.1016/j.biopsycho.2007.08.009  0.488
2008 Weickert CS, Rothmond DA, Hyde TM, Kleinman JE, Straub RE. Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients. Schizophrenia Research. 98: 105-10. PMID 17961984 DOI: 10.1016/J.Schres.2007.05.041  0.48
2008 Diaz-Asper CM, Goldberg TE, Kolachana BS, Straub RE, Egan MF, Weinberger DR. Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls. Biological Psychiatry. 63: 72-9. PMID 17707347 DOI: 10.1016/j.biopsych.2007.03.031  0.581
2007 Iizuka Y, Sei Y, Weinberger DR, Straub RE. Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12390-5. PMID 17989303 DOI: 10.1523/Jneurosci.1689-07.2007  0.623
2007 Buckholtz JW, Sust S, Tan HY, Mattay VS, Straub RE, Meyer-Lindenberg A, Weinberger DR, Callicott JH. fMRI evidence for functional epistasis between COMT and RGS4. Molecular Psychiatry. 12: 893-5, 885. PMID 17895922 DOI: 10.1038/sj.mp.4002008  0.603
2007 Mathew SV, Law AJ, Lipska BK, Dávila-García MI, Zamora ED, Mitkus SN, Vakkalanka R, Straub RE, Weinberger DR, Kleinman JE, Hyde TM. Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1. Human Molecular Genetics. 16: 2921-32. PMID 17884806 DOI: 10.1093/Hmg/Ddm253  0.567
2007 Straub RE, Lipska BK, Egan MF, Goldberg TE, Callicott JH, Mayhew MB, Vakkalanka RK, Kolachana BS, Kleinman JE, Weinberger DR. Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Molecular Psychiatry. 12: 854-69. PMID 17767149 DOI: 10.1038/sj.mp.4001988  0.74
2007 Huo L, Straub RE, Roca C, Schmidt PJ, Shi K, Vakkalanka R, Weinberger DR, Rubinow DR. Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene. Biological Psychiatry. 62: 925-33. PMID 17599809 DOI: 10.1016/j.biopsych.2006.12.019  0.536
2007 Fanous AH, Neale MC, Gardner CO, Webb BT, Straub RE, O'Neill FA, Walsh D, Riley BP, Kendler KS. Significant correlation in linkage signals from genome-wide scans of schizophrenia and schizotypy. Molecular Psychiatry. 12: 958-65. PMID 17440434 DOI: 10.1038/Sj.Mp.4001996  0.616
2007 Buckholtz JW, Meyer-Lindenberg A, Honea RA, Straub RE, Pezawas L, Egan MF, Vakkalanka R, Kolachana B, Verchinski BA, Sust S, Mattay VS, Weinberger DR, Callicott JH. Allelic variation in RGS4 impacts functional and structural connectivity in the human brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1584-93. PMID 17301167 DOI: 10.1523/JNEUROSCI.5112-06.2007  0.79
2007 Meyer-Lindenberg A, Straub RE, Lipska BK, Verchinski BA, Goldberg T, Callicott JH, Egan MF, Huffaker SS, Mattay VS, Kolachana B, Kleinman JE, Weinberger DR. Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition. The Journal of Clinical Investigation. 117: 672-82. PMID 17290303 DOI: 10.1172/JCI30413  0.725
2007 Fanous AH, Neale MC, Webb BT, Straub RE, Amdur RL, O'Neill FA, Walsh D, Riley BP, Kendler KS. A genome-wide scan for modifier loci in schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 589-95. PMID 17262803 DOI: 10.1002/Ajmg.B.30442  0.486
2007 Nicodemus KK, Kolachana BS, Vakkalanka R, Straub RE, Giegling I, Egan MF, Rujescu D, Weinberger DR. Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia. Human Genetics. 120: 889-906. PMID 17006672 DOI: 10.1007/s00439-006-0257-3  0.626
2007 Buckholtz JW, Prust M, Sust S, Tan HY, Mattay VS, Straub RE, Meyer-Lindenberg A, Weinberger DR, Callicott JH. Imaging epistasis in vivo: COMT and RGS4 Molecular Psychiatry. 12: 885. DOI: 10.1038/sj.mp.4002085  0.572
2006 Weickert C, Straub R, Kleinman J, Hyde T, Rothmond D. Reduced dysbindin (DTNBP1) mRNA in hippocampus of patients with schizophrenia. Acta Neuropsychiatrica. 18: 307-308. PMID 27397329 DOI: 10.1017/S0924270800031719  0.453
2006 Nicodemus KK, Luna A, Vakkalanka R, Goldberg T, Egan M, Straub RE, Weinberger DR. Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls. Molecular Psychiatry. 11: 1062-5. PMID 17130882 DOI: 10.1038/sj.mp.4001878  0.587
2006 Lipska BK, Mitkus S, Caruso M, Hyde TM, Chen J, Vakkalanka R, Straub RE, Weinberger DR, Kleinman JE. RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity. Human Molecular Genetics. 15: 2804-12. PMID 16905560 DOI: 10.1093/hmg/ddl222  0.545
2006 Straub RE, Weinberger DR. Schizophrenia genes - famine to feast. Biological Psychiatry. 60: 81-3. PMID 16843093 DOI: 10.1016/j.biopsych.2006.06.002  0.528
2006 Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M, Kendler KS, Kirov G, Heston LL, ... ... Straub RE, et al. Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biological Psychiatry. 60: 152-62. PMID 16631129 DOI: 10.1016/J.Biopsych.2006.02.015  0.664
2006 Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 6747-52. PMID 16618933 DOI: 10.1073/Pnas.0602002103  0.56
2006 Marenco S, Steele SU, Egan MF, Goldberg TE, Straub RE, Sharrief AZ, Weinberger DR. Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex. The American Journal of Psychiatry. 163: 740-2. PMID 16585454 DOI: 10.1176/appi.ajp.163.4.740  0.551
2006 Goldberg TE, Straub RE, Callicott JH, Hariri A, Mattay VS, Bigelow L, Coppola R, Egan MF, Weinberger DR. The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2022-32. PMID 16554747 DOI: 10.1038/sj.npp.1301049  0.713
2006 Lipska BK, Peters T, Hyde TM, Halim N, Horowitz C, Mitkus S, Weickert CS, Matsumoto M, Sawa A, Straub RE, Vakkalanka R, Herman MM, Weinberger DR, Kleinman JE. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Human Molecular Genetics. 15: 1245-58. PMID 16510495 DOI: 10.1093/Hmg/Ddl040  0.648
2005 Gornick MC, Addington AM, Sporn A, Gogtay N, Greenstein D, Lenane M, Gochman P, Ordonez A, Balkissoon R, Vakkalanka R, Weinberger DR, Rapoport JL, Straub RE. Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS). Journal of Autism and Developmental Disorders. 35: 831-8. PMID 16283082 DOI: 10.1007/S10803-005-0028-3  0.631
2005 Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Balkissoon R, Kolachana B, Goldberg TE, Weinberger DR. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 102: 8627-32. PMID 15939883 DOI: 10.1073/pnas.0500515102  0.766
2005 Bobb AJ, Addington AM, Sidransky E, Gornick MC, Lerch JP, Greenstein DK, Clasen LS, Sharp WS, Inoff-Germain G, Wavrant-De Vrièze F, Arcos-Burgos M, Straub RE, Hardy JA, Castellanos FX, Rapoport JL. Support for association between ADHD and two candidate genes: NET1 and DRD1. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 134: 67-72. PMID 15717291 DOI: 10.1002/Ajmg.B.30142  0.339
2005 Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Rapoport JL, Straub RE. GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss. Molecular Psychiatry. 10: 581-8. PMID 15505639 DOI: 10.1038/Sj.Mp.4001599  0.647
2004 Pezawas L, Verchinski BA, Mattay VS, Callicott JH, Kolachana BS, Straub RE, Egan MF, Meyer-Lindenberg A, Weinberger DR. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10099-102. PMID 15537879 DOI: 10.1523/JNEUROSCI.2680-04.2004  0.667
2004 Numakawa T, Yagasaki Y, Ishimoto T, Okada T, Suzuki T, Iwata N, Ozaki N, Taguchi T, Tatsumi M, Kamijima K, Straub RE, Weinberger DR, Kunugi H, Hashimoto R. Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Human Molecular Genetics. 13: 2699-708. PMID 15345706 DOI: 10.1093/hmg/ddh280  0.588
2004 Egan MF, Straub RE, Goldberg TE, Yakub I, Callicott JH, Hariri AR, Mattay VS, Bertolino A, Hyde TM, Shannon-Weickert C, Akil M, Crook J, Vakkalanka RK, Balkissoon R, Gibbs RA, et al. Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 101: 12604-9. PMID 15310849 DOI: 10.1073/Pnas.0405077101  0.737
2004 Weickert CS, Straub RE, McClintock BW, Matsumoto M, Hashimoto R, Hyde TM, Herman MM, Weinberger DR, Kleinman JE. Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain. Archives of General Psychiatry. 61: 544-55. PMID 15184234 DOI: 10.1001/Archpsyc.61.6.544  0.578
2004 Sporn AL, Addington AM, Gogtay N, Ordoñez AE, Gornick M, Clasen L, Greenstein D, Tossell JW, Gochman P, Lenane M, Sharp WS, Straub RE, Rapoport JL. Pervasive developmental disorder and childhood-onset schizophrenia: comorbid disorder or a phenotypic variant of a very early onset illness? Biological Psychiatry. 55: 989-94. PMID 15121482 DOI: 10.1016/J.Biopsych.2004.01.019  0.38
2004 Addington AM, Gornick M, Sporn AL, Gogtay N, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Straub RE, Rapoport JL. Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified. Biological Psychiatry. 55: 976-80. PMID 15121480 DOI: 10.1016/J.Biopsych.2004.01.024  0.599
2004 Sullivan PF, Neale BM, van den Oord E, Miles MF, Neale MC, Bulik CM, Joyce PR, Straub RE, Kendler KS. Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 126: 23-36. PMID 15048644 DOI: 10.1002/Ajmg.B.20138  0.383
2004 Fanous AH, Neale MC, Straub RE, Webb BT, O'Neill AF, Walsh D, Kendler KS. Clinical features of psychotic disorders and polymorphisms in HT2A, DRD2, DRD4, SLC6A3 (DAT1), and BDNF: a family based association study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 125: 69-78. PMID 14755448 DOI: 10.1002/Ajmg.B.20103  0.611
2004 Hashimoto R, Straub RE, Weickert CS, Hyde TM, Kleinman JE, Weinberger DR. Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia. Molecular Psychiatry. 9: 299-307. PMID 14569272 DOI: 10.1038/Sj.Mp.4001434  0.586
2003 Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV, Brzustowicz LM, Kaufmann CA, Garver DL, Gurling HM, Lindholm E, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. American Journal of Human Genetics. 73: 34-48. PMID 12802786 DOI: 10.1086/376549  0.475
2002 Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H, Bougueleret L, Barry C, Tanaka H, La Rosa P, Puech A, Tahri N, Cohen-Akenine A, Delabrosse S, Lissarrague S, ... ... Straub RE, et al. Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 99: 13675-80. PMID 12364586 DOI: 10.1073/Pnas.182412499  0.613
2002 Straub RE, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, O'Neill FA, Walsh D, Kendler KS. Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes. Molecular Psychiatry. 7: 542-59. PMID 12140777 DOI: 10.1038/Sj.Mp.4001051  0.768
2002 Straub RE, Jiang Y, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, Cesare AJ, Gibberman A, Wang X, O'Neill FA, Walsh D, et al. Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia. American Journal of Human Genetics. 71: 337-48. PMID 12098102 DOI: 10.1086/341750  0.822
2002 Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H, Bougueleret L, Barry C, Tanaka H, Rosa PL, Puech A, Tahri N, Cohen-Akenine A, Delabrosse S, Lissarrague S, ... ... Straub R, et al. Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia (vol 99, pg 13675, 2002) Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/Pnas.262645899  0.436
2001 Sullivan PF, Jiang Y, Neale MC, Kendler KS, Straub RE. Association of the tryptophan hydroxylase gene with smoking initiation but not progression to nicotine dependence. American Journal of Medical Genetics. 105: 479-84. PMID 11449402 DOI: 10.1002/Ajmg.1433  0.373
2001 Egan MF, Goldberg TE, Kolachana BS, Callicott JH, Mazzanti CM, Straub RE, Goldman D, Weinberger DR. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 98: 6917-22. PMID 11381111 DOI: 10.1073/Pnas.111134598  0.713
2001 Sullivan PF, O'Neill FA, Walsh D, Ma Y, Kendler KS, Straub RE. Analysis of epistasis in linked regions in the Irish study of high-density schizophrenia families. American Journal of Medical Genetics. 105: 266-70. PMID 11353447 DOI: 10.1002/ajmg.1324  0.512
2001 Sullivan PF, Neale MC, Silverman MA, Harris-Kerr C, Myakishev MV, Wormley B, Webb BT, Ma Y, Kendler KS, Straub RE. An association study of DRD5 with smoking initiation and progression to nicotine dependence. American Journal of Medical Genetics. 105: 259-65. PMID 11353446 DOI: 10.1002/Ajmg.1301  0.752
2001 Jiang Y, Wormley B, Wang X, Riley BP, Chen X, Kendler KS, Straub RE. Lack of evidence to support the strong association of NOTCH4 gene polymorphism and susceptibility to schizophrenia American Journal of Medical Genetics - Neuropsychiatric Genetics. 105: 571-572.  0.457
2000 Silverman MA, Neale MC, Sullivan PF, Harris-Kerr C, Wormley B, Sadek H, Ma Y, Kendler KS, Straub RE. Haplotypes of four novel single nucleotide polymorphisms in the nicotinic acetylcholine receptor beta2-subunit (CHRNB2) gene show no association with smoking initiation or nicotine dependence. American Journal of Medical Genetics. 96: 646-53. PMID 11054772 DOI: 10.1002/1096-8628(20001009)96:5<646::Aid-Ajmg10>3.0.Co;2-W  0.334
2000 Levinson DF, Holmans P, Straub RE, Owen MJ, Wildenauer DB, Gejman PV, Pulver AE, Laurent C, Kendler KS, Walsh D, Norton N, Williams NM, Schwab SG, Lerer B, Mowry BJ, et al. Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III. American Journal of Human Genetics. 67: 652-63. PMID 10924404 DOI: 10.1086/303041  0.487
2000 Ross DE, Kirkpatrick B, Karkowski LM, Straub RE, MacLean CJ, O'Neill FA, Compton AD, Murphy B, Walsh D, Kendler KS. Sibling correlation of deficit syndrome in the Irish study of high-density schizophrenia families. The American Journal of Psychiatry. 157: 1071-6. PMID 10873913 DOI: 10.1176/appi.ajp.157.7.1071  0.587
2000 MacLean CJ, Martin RB, Sham PC, Wang H, Straub RE, Kendler KS. The trimmed-haplotype test for linkage disequilibrium. American Journal of Human Genetics. 66: 1062-75. PMID 10712218 DOI: 10.1086/302796  0.399
2000 Kendler KS, Myers JM, O'Neill FA, Martin R, Murphy B, MacLean CJ, Walsh D, Straub RE. Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p in the Irish Study of High-Density Schizophrenia Families. The American Journal of Psychiatry. 157: 402-8. PMID 10698816 DOI: 10.1176/appi.ajp.157.3.402  0.604
2000 Fanous A, Neale M, MacLean C, Straub R, Ma Y, O'Neill A, Walsh D, Kendler KS. Quantitative trait loci analysis of high density schizophrenia families does not provide greater power than traditional linkage methods to detect susceptibility loci for schizophrenia American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 568-569.  0.405
1999 Hawi Z, Mynett-Johnson L, Murphy V, Straub RE, Kendler KS, Walsh D, McKeon P, Gill M. No evidence to support the association of the potassium channel gene hSKCa3 CAG repeat with schizophrenia or bipolar disorder in the Irish population. Molecular Psychiatry. 4: 488-91. PMID 10523823 DOI: 10.1038/Sj.Mp.4000560  0.502
1999 Hawi Z, Gibson S, Straub RE, Walsh D, Kendler KS, Gill M. Schizophrenia and HLA: No association with PCR-SSOP typed classical loci in a large Irish familial sample. American Journal of Medical Genetics. 88: 422-9. PMID 10402512 DOI: 10.1002/(SICI)1096-8628(19990820)88:4<422::AID-AJMG22>3.0.CO;2-#  0.47
1999 Gibson S, Hawi Z, Straub RE, Walsh D, Kendler KS, Gill M. HLA and schizophrenia: refutation of reported associations with A9 (A23/A24), DR4, and DQbeta1*0602. American Journal of Medical Genetics. 88: 416-21. PMID 10402511 DOI: 10.1002/(Sici)1096-8628(19990820)88:4<416::Aid-Ajmg21>3.0.Co;2-S  0.475
1999 Straub RE, Sullivan PF, Ma Y, Myakishev MV, Harris-Kerr C, Wormley B, Kadambi B, Sadek H, Silverman MA, Webb BT, Neale MC, Bulik CM, Joyce PR, Kendler KS. Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. Molecular Psychiatry. 4: 129-44. PMID 10208445 DOI: 10.1038/Sj.Mp.4000518  0.766
1999 Kendler KS, MacLean CJ, Ma Y, O'Neill FA, Walsh D, Straub RE. Marker-to-marker linkage disequilibrium on chromosomes 5q, 6p, and 8p in Irish high-density schizophrenia pedigrees. American Journal of Medical Genetics. 88: 29-33. PMID 10050963 DOI: 10.1002/(SICI)1096-8628(19990205)88:1<29::AID-AJMG5>3.0.CO;2-7  0.415
1998 Hawi Z, Straub RE, O'Neill A, Kendler KS, Walsh D, Gill M. No linkage or linkage disequilibrium between brain-derived neurotrophic factor (BDNF) dinucleotide repeat polymorphism and schizophrenia in Irish families. Psychiatry Research. 81: 111-6. PMID 9858028 DOI: 10.1016/S0165-1781(98)00076-6  0.511
1998 Vallada H, Curtis D, Sham P, Kunugi H, Zhao J, Murray R, McGuffin P, Nanko S, Owen M, Gill M, Collier D, Antonarakis S, Housman D, Kazazian H, Nestadt G, ... ... Straub R, et al. A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12 Schizophrenia Research. 32: 115-121. PMID 9713907 DOI: 10.1016/S0920-9964(98)00048-6  0.651
1998 Straub RE, MacLean CJ, Martin RB, Ma Y, Myakishev MV, Harris-Kerr C, Webb BT, O'Neill FA, Walsh D, Kendler KS. A schizophrenia locus may be located in region 10p15-p11. American Journal of Medical Genetics. 81: 296-301. PMID 9674974 DOI: 10.1002/(Sici)1096-8628(19980710)81:4<296::Aid-Ajmg4>3.0.Co;2-S  0.784
1998 Hawi Z, McCabe U, Straub RE, O'Neill A, Kendler KS, Walsh D, Gill M. Examination of new and reported data of the DRD3/MscI polymorphism: no support for the proposed association with schizophrenia. Molecular Psychiatry. 3: 150-5. PMID 9577839 DOI: 10.1038/Sj.Mp.4000362  0.569
1998 Hawi Z, Mynett-Johnson L, Murphy V, Straub RE, Kendler KS, Walsh D, McKeon P, Gill M. No evidence to support the association of the potassium channel gene hSKCa3 cag repeat with schizophrenia or bipolar affective disorder in irish population American Journal of Medical Genetics - Neuropsychiatric Genetics. 81: 508.  0.338
1997 Hawi Z, Myakishev MV, Straub RE, O'Neill A, Kendler KS, Walsh D, Gill M. No association or linkage between the 5-HT2a/T102C polymorphism and schizophrenia in Irish families. American Journal of Medical Genetics. 74: 370-3. PMID 9259371 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<370::Aid-Ajmg6>3.0.Co;2-T  0.824
1997 Straub RE, MacLean CJ, O'Neill FA, Walsh D, Kendler KS. Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families. Molecular Psychiatry. 2: 148-55. PMID 9106240 DOI: 10.1038/sj.mp.4000258  0.502
1997 Kendler KS, Karkowski-Shuman L, O'Neill FA, Straub RE, MacLean CJ, Walsh D. Resemblance of psychotic symptoms and syndromes in affected sibling pairs from the Irish Study of High-Density Schizophrenia Families: evidence for possible etiologic heterogeneity. The American Journal of Psychiatry. 154: 191-8. PMID 9016267 DOI: 10.1176/AJP.154.2.191  0.54
1996 Straub RE, MacLean CJ, Walsh D, Kendler KS. Support for schizophrenia vulnerability loci on chromosomes 6p and 8p from Irish families. Cold Spring Harbor Symposia On Quantitative Biology. 61: 823-33. PMID 9246507  0.365
1996 Gill M, Hawi Z, O'Neill FA, Walsh D, Straub RE, Kendler KS. Neurotrophin-3 gene polymorphisms and schizophrenia: no evidence for linkage or association. Psychiatric Genetics. 6: 183-6. PMID 9149322 DOI: 10.1097/00041444-199624000-00002  0.6
1996 Straub RE, MacLean CJ, Kendler KS. The putative schizophrenia locus on chromosome 6p: a brief overview of the linkage studies. Molecular Psychiatry. 1: 89-92. PMID 9118328  0.387
1996 Kendler KS, MacLean CJ, O'Neill FA, Burke J, Murphy B, Duke F, Shinkwin R, Easter SM, Webb BT, Zhang J, Walsh D, Straub RE. Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. The American Journal of Psychiatry. 153: 1534-40. PMID 8942448 DOI: 10.1176/Ajp.153.12.1534  0.62
1996 Kendler KS, O'Neill FA, Burke J, Murphy B, Duke F, Straub RE, Shinkwin R, Ni Nuallain M, MacLean CJ, Walsh D. Irish study on high-density schizophrenia families: field methods and power to detect linkage. American Journal of Medical Genetics. 67: 179-90. PMID 8723045 DOI: 10.1002/(SICI)1096-8628(19960409)67:2<179::AID-AJMG8>3.0.CO;2-N  0.512
1996 Kendler KS, Straub RE, MacLean CJ, Walsh D. Reflections on the evidence for a vulnerability locus for schizophrenia on chromosome 6p24-22. American Journal of Medical Genetics. 67: 124-6. PMID 8723037 DOI: 10.1002/ajmg.1320670203  0.507
1996 Gill M, Vallada H, Collier D, Sham P, Holmans P, Murray R, McGuffin P, Nanko S, Owen M, Antonarakis S, Housman D, Kazazian H, Nestadt G, Pulver AE, Straub RE, et al. A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). American Journal of Medical Genetics. 67: 40-5. PMID 8678112 DOI: 10.1002/(Sici)1096-8628(19960216)67:1<40::Aid-Ajmg6>3.0.Co;2-W  0.493
1996 Kendler K, Straub R, MacLean C, Walsh D. Linkage studies in Irish Highdensity Schizophrenfa Families Biological Psychiatry. 39: 614. DOI: 10.1016/0006-3223(96)84330-7  0.403
1995 Straub RE, MacLean CJ, O'Neill FA, Burke J, Murphy B, Duke F, Shinkwin R, Webb BT, Zhang J, Walsh D. A potential vulnerability locus for schizophrenia on chromosome 6p24-22: evidence for genetic heterogeneity. Nature Genetics. 11: 287-93. PMID 7581452 DOI: 10.1038/Ng1195-287  0.425
1995 Kendler K, Straub R, MacLean C, Walsh D. A possible susceptibility locus for schizophrenia in the 6P 22–25 region in irish high density families Schizophrenia Research. 15: 41-42. DOI: 10.1016/0920-9964(95)95134-U  0.576
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