Akira Sawa - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
psychiatry

305 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mueller FS, Richetto J, Hayes LN, Zambon A, Pollak DD, Sawa A, Meyer U, Weber-Stadlbauer U. Influence of poly(I:C) variability on thermoregulation, immune responses and pregnancy outcomes in mouse models of maternal immune activation. Brain, Behavior, and Immunity. PMID 30980948 DOI: 10.1016/j.bbi.2019.04.019  0.36
2019 Tharakan R, Kreimer S, Ubaida-Mohien C, Lavoie J, Olexiouk V, Menschaert G, Ingolia NT, Cole RN, Ishizuka K, Sawa A, Nucifora LG. A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics. Neuroscience Research. PMID 30862443 DOI: 10.1016/j.neures.2019.02.006  1
2019 Namkung H, Lee BJ, Sawa A. Causal Inference on Pathophysiological Mediators in Psychiatry. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30850434 DOI: 10.1101/sqb.2018.83.037655  1
2019 Hikida T, Morita M, Kuroiwa M, Macpherson T, Shuto T, Sotogaku N, Niwa M, Sawa A, Nishi A. Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice. Neuroscience Research. PMID 30831136 DOI: 10.1016/j.neures.2019.02.007  0.96
2019 Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A. Glutathione -transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. Science Signaling. 12. PMID 30783009 DOI: 10.1126/scisignal.aar2124  0.68
2019 Sedlak TW, Paul BD, Parker GM, Hester LD, Snowman AM, Taniguchi Y, Kamiya A, Snyder SH, Sawa A. The glutathione cycle shapes synaptic glutamate activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30692251 DOI: 10.1073/pnas.1817885116  1
2019 Okada N, Yahata N, Koshiyama D, Morita K, Sawada K, Kanata S, Fujikawa S, Sugimoto N, Toriyama R, Masaoka M, Koike S, Araki T, Kano Y, Endo K, Yamasaki S, ... ... Sawa A, et al. Neurometabolic and functional connectivity basis of prosocial behavior in early adolescence. Scientific Reports. 9: 732. PMID 30679738 DOI: 10.1038/s41598-018-38355-z  0.52
2019 Wang AM, Pradhan S, Coughlin JM, Trivedi A, DuBois SL, Crawford JL, Sedlak TW, Nucifora FC, Nestadt G, Nucifora LG, Schretlen DJ, Sawa A, Barker PB. Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis. Jama Psychiatry. PMID 30624573 DOI: 10.1001/jamapsychiatry.2018.3637  0.92
2018 Coughlin J, Du Y, Crawford JL, Rubin LH, Behnam Azad B, Lesniak WG, Horti AG, Schretlen DJ, Sawa A, Pomper MG. The availability of the α7 nicotinic acetylcholine receptor in recent-onset psychosis: a study using F-ASEM PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30573639 DOI: 10.2967/jnumed.118.213686  0.8
2018 Kamath V, Crawford J, DuBois S, Nucifora FC, Nestadt G, Sawa A, Schretlen D. Contributions of olfactory and neuropsychological assessment to the diagnosis of first-episode schizophrenia. Neuropsychology. PMID 30475048 DOI: 10.1037/neu0000502  0.36
2018 Nucifora FC, Woznica E, Lee BJ, Cascella N, Sawa A. Treatment resistant schizophrenia: Clinical, biological, and therapeutic perspectives. Neurobiology of Disease. PMID 30170114 DOI: 10.1016/j.nbd.2018.08.016  0.76
2018 Kano SI, Hodgkinson CA, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, Choi EY, Chang DJ, Chen Y, Velivela SD, Leister F, Wood J, Chowdari K, Ducci F, Caycedo DA, ... ... Sawa A, et al. Host-parasite interaction associated with major mental illness. Molecular Psychiatry. PMID 30127472 DOI: 10.1038/s41380-018-0217-z  1
2018 Sumitomo A, Horike K, Hirai K, Butcher N, Boot E, Sakurai T, Nucifora FC, Bassett AS, Sawa A, Tomoda T. A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia. Science Advances. 4: eaar6637. PMID 30116778 DOI: 10.1126/sciadv.aar6637  0.72
2018 Cardarelli RA, Martin R, Jaaro-Peled H, Sawa A, Powell EM, O'Donnell P. Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex. Molecular Neuropsychiatry. 4: 20-29. PMID 29998115 DOI: 10.1159/000488030  1
2018 Namkung H, Kim SH, Sawa A. The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology: (Trends in Neuroscience 40, 200-207, 2017). Trends in Neurosciences. PMID 29895478 DOI: 10.1016/j.tins.2018.05.004  1
2018 Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, ... ... Sawa A, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Human Molecular Genetics. PMID 29893844 DOI: 10.1093/hmg/ddy219  1
2018 Sumitomo A, Saka A, Ueta K, Horike K, Hirai K, Gamo NJ, Hikida T, Nakayama KI, Sawa A, Sakurai T, Tomoda T. Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in -Deficient Mice. Molecular Neuropsychiatry. 3: 223-233. PMID 29888233 DOI: 10.1159/000488081  0.96
2018 Sedlak TW, Nucifora LG, Koga M, Shaffer LS, Higgs C, Tanaka T, Wang AM, Coughlin JM, Barker PB, Fahey JW, Sawa A. Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study. Molecular Neuropsychiatry. 3: 214-222. PMID 29888232 DOI: 10.1159/000487639  0.92
2018 Lockhart S, Sawa A, Niwa M. Developmental trajectories of brain maturation and behavior: Relevance to major mental illnesses. Journal of Pharmacological Sciences. PMID 29773518 DOI: 10.1016/j.jphs.2018.04.008  0.68
2018 McLean CK, Narayan S, Lin SY, Rai N, Chung Y, Hipolito MS, Cascella NG, Nurnberger JI, Ishizuka K, Sawa AS, Nwulia EA. Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder. Translational Psychiatry. 8: 81. PMID 29666369 DOI: 10.1038/s41398-018-0126-6  1
2018 Srivastava R, Faust T, Ramos A, Ishizuka K, Sawa A. Dynamic Changes of the Mitochondria in Psychiatric Illnesses: New Mechanistic Insights From Human Neuronal Models. Biological Psychiatry. PMID 29486891 DOI: 10.1016/j.biopsych.2018.01.007  1
2018 Posporelis S, Coughlin JM, Marsman A, Pradhan S, Tanaka T, Wang H, Varvaris M, Ward R, Higgs C, Edwards JA, Ford CN, Kim PK, Lloyd AM, Edden RAE, Schretlen DJ, ... ... Sawa A, et al. Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 3: 248-254. PMID 29486866 DOI: 10.1016/j.bpsc.2017.04.003  0.68
2018 Ooms M, Tsujikawa T, Lohith TG, Mabins SN, Zoghbi SS, Sumitomo A, Jaaro-Peled H, Kimura Y, Telu S, Pike VW, Tomoda T, Innis RB, Sawa A, Fujita M. [C]( R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18758997. PMID 29430995 DOI: 10.1177/0271678X18758997  1
2018 Fukudome D, Hayes LN, Faust TE, Foss CA, Kondo MA, Lee BJ, Saito A, Kano SI, Coughlin JM, Kamiya A, Pomper MG, Sawa A, Niwa M. Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances. Schizophrenia Research. PMID 29398205 DOI: 10.1016/j.schres.2018.01.015  0.92
2017 Gault JM, Davis R, Cascella NG, Saks ER, Corripio-Collado I, Anderson WS, Olincy A, Thompson JA, Pomarol-Clotet E, Sawa A, Daskalakis ZJ, Lipsman N, Abosch A. Approaches to neuromodulation for schizophrenia. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29242310 DOI: 10.1136/jnnp-2017-316946  0.68
2017 Park SJ, Lee SB, Suh Y, Kim SJ, Lee N, Hong JH, Park C, Woo Y, Ishizuka K, Kim JH, Berggren PO, Sawa A, Park SK. DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM. Cell Reports. 21: 2748-2759. PMID 29212023 DOI: 10.1016/j.celrep.2017.11.043  1
2017 Sagata N, Kato TA, Kano SI, Ohgidani M, Shimokawa N, Sato-Kasai M, Hayakawa K, Kuwano N, Wilson AM, Ishizuka K, Kato S, Nakahara T, Nakahara-Kido M, Setoyama D, Sakai Y, ... ... Sawa A, et al. Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: a pilot study. Scientific Reports. 7: 13905. PMID 29066822 DOI: 10.1038/s41598-017-14440-7  1
2017 Kamath V, Lasutschinkow P, Ishizuka K, Sawa A. Olfactory Functioning in First-Episode Psychosis. Schizophrenia Bulletin. PMID 28981913 DOI: 10.1093/schbul/sbx107  1
2017 Yang K, Sawa A. Open Sesame: Open Chromatin Regions Shed Light onto Non-coding Risk Variants. Cell Stem Cell. 21: 285-287. PMID 28886358 DOI: 10.1016/j.stem.2017.08.006  1
2017 Mills EW, Shaffer LS, Goes FS, Sawa A, Nucifora FC. Case of Secondary Tics Associated With Olanzapine in an Adult. Frontiers in Psychiatry. 8: 150. PMID 28861008 DOI: 10.3389/fpsyt.2017.00150  0.32
2017 Nucifora FC, Mihaljevic M, Lee BJ, Sawa A. Clozapine as a Model for Antipsychotic Development. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28653280 DOI: 10.1007/s13311-017-0552-9  0.76
2017 Shao L, Lu B, Wen Z, Teng S, Wang L, Zhao Y, Wang L, Ishizuka K, Xu X, Sawa A, Song H, Ming G, Zhong Y. Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways. Human Molecular Genetics. PMID 28472294 DOI: 10.1093/hmg/ddx147  1
2017 Segal-Gavish H, Gazit N, Barhum Y, Ben-Zur T, Taler M, Henry Hornfeld S, Gil-Ad I, Weizman A, Slutsky I, Niwa M, Kamiya A, Sawa A, Offen D, Barzilay R. BDNF Overexpression Prevents Cognitive Deficit Elicited by Adolescent Cannabis Exposure and Host Susceptibility Interaction. Human Molecular Genetics. PMID 28402427 DOI: 10.1093/hmg/ddx139  0.92
2017 Andrews CE, Baker K, Howell CJ, Cuerdo A, Roberts JA, Chaudhary A, Lechich S, Nucifora LG, Vaidya D, Mojtabai R, Margolis RL, Sawa A, Nucifora FC. Risk of Hospitalization Due to Medication Nonadherence Identified Through EMRs of Patients With Psychosis. Psychiatric Services (Washington, D.C.). appips201600334. PMID 28366115 DOI: 10.1176/appi.ps.201600334  0.4
2017 Lavoie J, Sawa A, Ishizuka K. Application of olfactory tissue and its neural progenitors to schizophrenia and psychiatric research. Current Opinion in Psychiatry. PMID 28333692 DOI: 10.1097/YCO.0000000000000327  1
2017 Namkung H, Kim SH, Sawa A. The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology. Trends in Neurosciences. PMID 28314446 DOI: 10.1016/j.tins.2017.02.002  1
2017 Tanaka M, Ishizuka K, Nekooki-Machida Y, Endo R, Takashima N, Sasaki H, Komi Y, Gathercole A, Huston E, Ishii K, Hui KK, Kurosawa M, Kim SH, Nukina N, Takimoto E, ... ... Sawa A, et al. Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease. The Journal of Clinical Investigation. PMID 28263187 DOI: 10.1172/JCI85594  1
2017 Lavoie J, Gassó Astorga P, Segal-Gavish H, Wu YC, Chung Y, Cascella NG, Sawa A, Ishizuka K. The Olfactory Neural Epithelium As a Tool in Neuroscience. Trends in Molecular Medicine. PMID 28108112 DOI: 10.1016/j.molmed.2016.12.010  1
2016 Lee BJ, Marchionni L, Andrews CE, Norris AL, Nucifora LG, Wu YC, Wright RA, Pevsner J, Ross CA, Margolis RL, Sawa A, Nucifora FC. Analysis of differential gene expression mediated by clozapine in human postmortem brains. Schizophrenia Research. PMID 28038920 DOI: 10.1016/j.schres.2016.12.017  0.76
2016 Sumitomo A, Ueta K, Mauchi S, Hirai K, Horike K, Hikida T, Sakurai T, Sawa A, Tomoda T. Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits. Neuroscience Research. PMID 28017600 DOI: 10.1016/j.neures.2016.12.004  0.96
2016 Coughlin JM, Wang Y, Minn I, Bienko N, Ambinder EB, Xu X, Peters ME, Dougherty JW, Vranesic M, Koo SM, Ahn HH, Lee M, Cottrell C, Sair HI, Sawa A, et al. Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players. Jama Neurology. PMID 27893897 DOI: 10.1001/jamaneurol.2016.3764  0.84
2016 Coughlin JM, Hayes LN, Tanaka T, Xiao M, Yolken RH, Worley P, Leweke FM, Sawa A. Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features. Schizophrenia Research. PMID 27889384 DOI: 10.1016/j.schres.2016.10.040  0.84
2016 Gamo NJ, Birknow MR, Sullivan D, Kondo MA, Horiuchi Y, Sakurai T, Slusher BS, Sawa A. Valley of death: A proposal to build a "translational bridge" for the next generation. Neuroscience Research. PMID 27876581 DOI: 10.1016/j.neures.2016.11.003  0.96
2016 Nucifora LG, Wu YC, Lee BJ, Sha L, Margolis RL, Ross CA, Sawa A, Nucifora FC. A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation. Molecular Neuropsychiatry. 2: 133-144. PMID 27867938 DOI: 10.1159/000447358  0.76
2016 Morita M, Wang Y, Sasaoka T, Okada K, Niwa M, Sawa A, Hikida T. Dopamine D2L Receptor Is Required for Visual Discrimination and Reversal Learning. Molecular Neuropsychiatry. 2: 124-132. PMID 27867937 DOI: 10.1159/000447970  0.96
2016 Tanaka T, Matsuda T, Hayes LN, Yang S, Rodriguez K, Severance EG, Yolken RH, Sawa A, Eaton W. Infection and inflammation in schizophrenia and bipolar disorder. Neuroscience Research. PMID 27856235 DOI: 10.1016/j.neures.2016.11.002  0.56
2016 Hayes LN, Shevelkin A, Zeledon M, Steel G, Chen PL, Obie C, Pulver A, Avramopoulos D, Valle D, Sawa A, Pletnikov MV. Neuregulin 3 Knockout Mice Exhibit Behaviors Consistent with Psychotic Disorders. Molecular Neuropsychiatry. 2: 79-87. PMID 27606322 DOI: 10.1159/000445836  1
2016 Xia M, Broek JA, Jouroukhin Y, Schoenfelder J, Abazyan S, Jaaro-Peled H, Sawa A, Bahn S, Pletnikov M. Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study. Molecular Neuropsychiatry. 2: 28-36. PMID 27606318 DOI: 10.1159/000444587  1
2016 Tankou S, Ishii K, Elliott C, Yalla KC, Day JP, Furukori K, Kubo KI, Brandon NJ, Tang Q, Hayward G, Nakajima K, Houslay MD, Kamiya A, Baillie G, Ishizuka K, ... Sawa A, et al. SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex. Molecular Neuropsychiatry. 2: 20-27. PMID 27525255 DOI: 10.1159/000444257  1
2016 Sawa A, Sedlak TW. Oxidative stress and inflammation in schizophrenia. Schizophrenia Research. PMID 27395767 DOI: 10.1016/j.schres.2016.06.014  0.92
2016 Wang Y, Coughlin JM, Ma S, Endres CJ, Kassiou M, Sawa A, Dannals RF, Petri M, Pomper MG. Neuroimaging of translocator protein in patients with systemic lupus erythematosus: a pilot study using [11C]DPA-713 positron emission tomography. Lupus. PMID 27387599 DOI: 10.1177/0961203316657432  0.84
2016 Saito A, Taniguchi Y, Kim SH, Selvakumar B, Perez G, Ballinger MD, Zhu X, Sabra J, Jallow M, Yan P, Ito K, Rajendran S, Hirotsune S, Wynshaw-Boris A, Snyder SH, ... Sawa A, et al. Developmental Alcohol Exposure Impairs Activity-Dependent S-Nitrosylation of NDEL1 for Neuronal Maturation. Cerebral Cortex (New York, N.Y. : 1991). PMID 27371763 DOI: 10.1093/cercor/bhw201  1
2016 Jaaro-Peled H, Altimus C, LeGates T, Cash-Padgett T, Zoubovsky S, Hikida T, Ishizuka K, Hattar S, Mongrain V, Sawa A. Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1. Neuroscience Research. PMID 27354230 DOI: 10.1016/j.neures.2016.06.006  1
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Sawa A, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/j.biopsych.2016.05.004  1
2016 Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A, Hikida T. Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCage. Learning & Memory (Cold Spring Harbor, N.Y.). 23: 359-64. PMID 27317196 DOI: 10.1101/lm.042507.116  0.96
2016 Nucifora FC, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, et al. Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. Nature Communications. 7: 11792. PMID 27273569 DOI: 10.1038/ncomms11792  1
2016 Kim SH, Shahani N, Bae BI, Sbodio JI, Chung Y, Nakaso K, Paul BD, Sawa A. Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53. Human Molecular Genetics. PMID 27206983 DOI: 10.1093/hmg/ddw115  1
2016 Coughlin JM, Wang Y, Ambinder EB, Ward RE, Minn I, Vranesic M, Kim PK, Ford CN, Higgs C, Hayes LN, Schretlen DJ, Dannals RF, Kassiou M, Sawa A, Pomper MG. In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [(11)C]DPA-713 PET and analysis of CSF and plasma. Translational Psychiatry. 6: e777. PMID 27070405 DOI: 10.1038/tp.2016.40  0.84
2016 Furukubo-Tokunaga K, Kurita K, Honjo K, Pandey H, Ando T, Takayama K, Arai Y, Mochizuki H, Ando M, Kamiya A, Sawa A. DISC1 causes associative memory and neurodevelopmental defects in fruit flies. Molecular Psychiatry. PMID 26976042 DOI: 10.1038/mp.2016.15  0.92
2016 Niwa M, Lee RS, Tanaka T, Okada K, Kano SI, Sawa A. A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons. Human Molecular Genetics. PMID 26908623 DOI: 10.1093/hmg/ddw019  0.56
2016 Kondo MA, Fukudome D, Smith DR, Gallagher M, Kamiya A, Sawa A. Dimensional assessment of behavioral changes in the cuprizone short-term exposure model for psychosis. Neuroscience Research. PMID 26869217 DOI: 10.1016/j.neures.2016.01.006  1
2016 Sawa A, Ishizuka K, Katsanis N. The potential of DISC1 protein as a therapeutic target for mental illness. Expert Opinion On Therapeutic Targets. PMID 26810812 DOI: 10.1517/14728222.2016.1146694  1
2016 Owen MJ, Sawa A, Mortensen PB. Schizophrenia. Lancet (London, England). PMID 26777917 DOI: 10.1016/S0140-6736(15)01121-6  0.92
2016 Tomoda T, Sumitomo A, Jaaro-Peled H, Sawa A. Utility and validity of DISC1 mouse models in biological psychiatry. Neuroscience. PMID 26768401 DOI: 10.1016/j.neuroscience.2015.12.061  1
2015 Hunsberger JG, Rao M, Kurtzberg J, Bulte JW, Atala A, LaFerla FM, Greely HT, Sawa A, Gandy S, Schneider LS, Doraiswamy PM. Accelerating stem cell trials for Alzheimer's disease. The Lancet. Neurology. PMID 26704439 DOI: 10.1016/S1474-4422(15)00332-4  0.92
2015 Seshadri S, Faust T, Ishizuka K, Delevich K, Chung Y, Kim SH, Cowles M, Niwa M, Jaaro-Peled H, Tomoda T, Lai C, Anton ES, Li B, Sawa A. Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex. Nature Communications. 6: 10118. PMID 26656849 DOI: 10.1038/ncomms10118  1
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... Sawa A, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/j.stemcr.2015.10.011  1
2015 Koga M, Serritella AV, Sawa A, Sedlak TW. Implications for reactive oxygen species in schizophrenia pathogenesis. Schizophrenia Research. PMID 26589391 DOI: 10.1016/j.schres.2015.06.022  0.92
2015 Zeledón M, Eckart N, Taub M, Vernon H, Szymanksi M, Wang R, Chen PL, Nestadt G, McGrath JA, Sawa A, Pulver AE, Avramopoulos D, Valle D. Identification and functional studies of regulatory variants responsible for the association of NRG3 with a delusion phenotype in schizophrenia. Molecular Neuropsychiatry. 1: 36-46. PMID 26528484 DOI: 10.1159/000371518  0.32
2015 Hayashi Y, Sawa A, Hikida T. Impaired hippocampal activity at the goal zone on the place preference task in a DISC1 mouse model. Neuroscience Research. PMID 26497623 DOI: 10.1016/j.neures.2015.10.005  1
2015 Cash-Padgett T, Sawa A, Jaaro-Peled H. Increased stereotypy in conditional Cxcr4 knockout mice. Neuroscience Research. PMID 26458529 DOI: 10.1016/j.neures.2015.10.001  0.92
2015 Ueda S, Niwa M, Hioki H, Sohn J, Kaneko T, Sawa A, Sakurai T. Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex. Molecular Neuropsychiatry. 1: 94-104. PMID 26457295 DOI: 10.1159/000430095  0.68
2015 Passeri E, Jones-Brando L, Bordón C, Sengupta S, Wilson AM, Primerano A, Rapoport JL, Ishikuza K, Kano SI, Yolken RH, Sawa A. Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls. Microbes and Infection / Institut Pasteur. PMID 26432947 DOI: 10.1016/j.micinf.2015.09.023  0.68
2015 Altimus C, Harrold J, Jaaro-Peled H, Sawa A, Foster DJ. Disordered ripples are a common feature of genetically distinct mouse models relevant to schizophrenia. Molecular Neuropsychiatry. 1: 52-59. PMID 26417572 DOI: 10.1159/000380765  1
2015 Sakurai T, Gamo NJ, Hikida T, Kim SH, Murai T, Tomoda T, Sawa A. Converging models of schizophrenia - Network alterations of prefrontal cortex underlying cognitive impairments. Progress in Neurobiology. PMID 26408506 DOI: 10.1016/j.pneurobio.2015.09.010  1
2015 Landek-Salgado MA, Faust TE, Sawa A. Molecular substrates of schizophrenia: homeostatic signaling to connectivity. Molecular Psychiatry. PMID 26390828 DOI: 10.1038/mp.2015.141  0.68
2015 Passeri E, Wilson AM, Primerano A, Kondo MA, Sengupta S, Srivastava R, Koga M, Obie C, Zandi PP, Goes FS, Valle D, Rapoport JL, Sawa A, Kano SI, Ishizuka K. Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities. Neuroscience Research. PMID 26260244 DOI: 10.1016/j.neures.2015.07.011  1
2015 Posporelis S, Paspali A, Takayanagi Y, Sawa A, Banerjea P, Kyriakopoulos M. Demographic and clinical correlates of suicidality in adolescents attending a specialist community mental health service: a naturalistic study. Journal of Mental Health (Abingdon, England). 1-5. PMID 26203534 DOI: 10.3109/09638237.2015.1022249  1
2015 Rais R, Wozniak K, Wu Y, Niwa M, Stathis M, Alt J, Giroux M, Sawa A, Rojas C, Slusher BS. Selective CNS Uptake of the GCP-II Inhibitor 2-PMPA following Intranasal Administration. Plos One. 10: e0131861. PMID 26151906 DOI: 10.1371/journal.pone.0131861  0.68
2015 Ballinger MD, Saito A, Abazyan B, Taniguchi Y, Huang CH, Ito K, Zhu X, Segal H, Jaaro-Peled H, Sawa A, Mackie K, Pletnikov MV, Kamiya A. Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory. Neurobiology of Disease. PMID 26093170 DOI: 10.1016/j.nbd.2015.06.006  1
2015 Nomura J, Jaaro-Peled H, Lewis E, Nuñez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, ... ... Sawa A, et al. Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice. Molecular Psychiatry. PMID 26008737 DOI: 10.1038/mp.2015.61  1
2015 Kida S, Sawa A, Ikeda K. Elucidating mechanisms for mental disorders: from specific molecules to pathology. Current Molecular Medicine. 15: 191-2. PMID 25950755  1
2015 Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, Shahani N, Itakura M, Ono Y, Azuma YT, Inui T, Kamiya A, Sawa A, Takeuchi T. Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. The Journal of Biological Chemistry. 290: 14493-503. PMID 25882840 DOI: 10.1074/jbc.M114.635607  1
2015 Barodia SK, Park SK, Ishizuka K, Sawa A, Kamiya A. Half-life of DISC1 protein and its pathological significance under hypoxia stress. Neuroscience Research. 97: 1-6. PMID 25738396 DOI: 10.1016/j.neures.2015.02.008  1
2015 Sawa A, Kida S, Ikeda K. Microphenotypes of mental disorders: a systematic approach to study disease mechanisms. Current Molecular Medicine. 15: 109-10. PMID 25732154  1
2015 Coughlin JM, Tanaka T, Marsman A, Wang H, Bonekamp S, Kim PK, Higgs C, Varvaris M, Edden RA, Pomper M, Schretlen D, Barker PB, Sawa A. Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia. Current Molecular Medicine. 15: 176-83. PMID 25732147  1
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, ... ... Sawa A, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146  1
2015 Zoubovsky S, Oh EC, Cash-Padgett T, Johnson AW, Hou Z, Mori S, Gallagher M, Katsanis N, Sawa A, Jaaro-Peled H. Neuroanatomical and behavioral deficits in mice haploinsufficient for Pericentriolar material 1 (Pcm1). Neuroscience Research. PMID 25697395 DOI: 10.1016/j.neures.2015.02.002  1
2015 Coughlin JM, Wang Y, Munro CA, Ma S, Yue C, Chen S, Airan R, Kim PK, Adams AV, Garcia C, Higgs C, Sair HI, Sawa A, Smith G, Lyketsos CG, et al. Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study. Neurobiology of Disease. 74: 58-65. PMID 25447235 DOI: 10.1016/j.nbd.2014.10.019  1
2015 Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A. Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade. The Journal of Biological Chemistry. 290: 56-64. PMID 25391652 DOI: 10.1074/jbc.M114.596205  1
2015 Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. DISC1 regulates trafficking and processing of APP and Aβ generation. Molecular Psychiatry. 20: 874-9. PMID 25224257 DOI: 10.1038/mp.2014.100  1
2015 Tomioka Y, Ito T, Sawa A. Evolutions of metallic ferromagnetism and magnetotransport properties of La1-xBaxMnO3 single crystals with 0 ≤ x ≤ 0.5 Journal of the Physical Society of Japan. 84. DOI: 10.7566/JPSJ.84.024703  0.36
2015 Miranda E, Jimenez D, Blasco J, Sune J, Tsurumaki-Fukuchi A, Yamada H, Sawa A. Modeling of the I-V and I-t characteristics of multiferroic BiFeO3 layers Proceedings of the 2015 10th Spanish Conference On Electron Devices, Cde 2015. DOI: 10.1109/CDE.2015.7087449  0.36
2015 Nakao H, Sudayama T, Kubota M, Okamoto J, Yamasaki Y, Murakami Y, Yamada H, Sawa A, Iwasa K. Magnetic and electronic states in (LaMnO3)2(SrMnO3)2 superlattice exhibiting a large negative magnetoresistance Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.245104  0.36
2015 Matsuzaki H, Nishioka H, Uemura H, Sawa A, Sota S, Tohyama T, Okamoto H. Ultrafast charge and lattice dynamics in one-dimensional Mott insulator of CuO-chain compound Ca2CuO3 investigated by femtosecond absorption spectroscopy Physical Review B - Condensed Matter and Materials Physics. 91. DOI: 10.1103/PhysRevB.91.081114  0.36
2015 Liu L, Tsurumaki-Fukuchi A, Yamada H, Sawa A. Ca doping dependence of resistive switching characteristics in ferroelectric capacitors comprising Ca-doped BiFeO3 Journal of Applied Physics. 118. DOI: 10.1063/1.4936308  0.36
2015 Miyazaki K, Shibuya K, Suzuki M, Wado H, Sawa A. High temperature coefficient of resistance of low-temperature-grown VO2 films on TiO2-buffered SiO2/Si (100) substrates Journal of Applied Physics. 118. DOI: 10.1063/1.4927746  0.36
2015 Harano T, Shibata G, Yoshimatsu K, Ishigami K, Verma VK, Takahashi Y, Kadono T, Yoshida T, Fujimori A, Koide T, Chang FH, Lin HJ, Huang DJ, Chen CT, Xiang PH, ... ... Sawa A, et al. Phase diagram of Ca1-xCexMnO3 thin films studied by X-ray magnetic circular dichroism Solid State Communications. 207: 50-53. DOI: 10.1016/j.ssc.2014.08.003  0.36
2015 Chadwick LH, Sawa A, Yang IV, Baccarelli A, Breakefield XO, Deng HW, Dolinoy DC, Fallin MD, Holland NT, Houseman EA, Lomvardas S, Rao M, Satterlee JS, Tyson FL, Vijayanand P, et al. New insights and updated guidelines for epigenome-wide association studies Neuroepigenetics. 1: 14-19. DOI: 10.1016/j.nepig.2014.10.004  1
2015 Li BS, Matsui Y, Miyamoto T, Yada H, Sawa A, Okamoto H. Epitaxial growth of high quality La2CuO4 film on LaSrAlO4 substrate with introduction of ultrathin amorphous layer of La2CuO4 Journal of Crystal Growth. 425: 230-233. DOI: 10.1016/j.jcrysgro.2015.04.005  0.36
2015 Yamada H, Tsurumaki-Fukuchi A, Kobayashi M, Nagai T, Toyosaki Y, Kumigashira H, Sawa A. Strong surface-termination effect on electroresistance in ferroelectric tunnel junctions Advanced Functional Materials. 25: 2708-2714. DOI: 10.1002/adfm.201500371  0.36
2014 Sawa A. [Mind the gap: towards integrative perspectives of psychiatry]. Seishin Shinkeigaku Zasshi = Psychiatria Et Neurologia Japonica. 116: 873-9. PMID 25672214  1
2014 Narayan S, McLean C, Sawa A, Lin SY, Rai N, Hipolito MS, Cascella N, Nurnberger JJ, Ishizuka K, Nwulia EA. Olfactory neurons obtained through nasal biopsy combined with laser-capture microdissection: a potential approach to study treatment response in mental disorders. Journal of Visualized Experiments : Jove. PMID 25549156 DOI: 10.3791/51853  1
2014 Takayanagi Y, Petersen L, Laursen TM, Cascella NG, Sawa A, Mortensen PB, Eaton WW. Risk of schizophrenia spectrum and affective disorders associated with small for gestational age birth and height in adulthood. Schizophrenia Research. 160: 230-2. PMID 25458575 DOI: 10.1016/j.schres.2014.10.018  1
2014 Lee RS, Sawa A. Environmental stressors and epigenetic control of the hypothalamic-pituitary-adrenal axis. Neuroendocrinology. 100: 278-87. PMID 25427939 DOI: 10.1159/000369585  1
2014 Sawa A, Seidman LJ. Is prophylactic psychiatry around the corner? combating adolescent oxidative stress for adult psychosis and schizophrenia. Neuron. 83: 991-3. PMID 25189204 DOI: 10.1016/j.neuron.2014.08.028  1
2014 Ramos A, Rodríguez-Seoane C, Rosa I, Trossbach SV, Ortega-Alonso A, Tomppo L, Ekelund J, Veijola J, Järvelin MR, Alonso J, Veiga S, Sawa A, Hennah W, García A, Korth C, et al. Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1. Human Molecular Genetics. 23: 5859-65. PMID 24934694 DOI: 10.1093/hmg/ddu303  1
2014 Gamo NJ, Sawa A. Human stem cells and surrogate tissues for basic and translational study of mental disorders. Biological Psychiatry. 75: 918-9. PMID 24862565 DOI: 10.1016/j.biopsych.2014.03.025  1
2014 Hayes LN, Severance EG, Leek JT, Gressitt KL, Rohleder C, Coughlin JM, Leweke FM, Yolken RH, Sawa A. Inflammatory molecular signature associated with infectious agents in psychosis. Schizophrenia Bulletin. 40: 963-72. PMID 24743863 DOI: 10.1093/schbul/sbu052  1
2014 Mojtabai R, Cullen B, Everett A, Nugent KL, Sawa A, Sharifi V, Takayanagi Y, Toroney JS, Eaton WW. Reasons for not seeking general medical care among individuals with serious mental illness. Psychiatric Services (Washington, D.C.). 65: 818-21. PMID 24733659 DOI: 10.1176/appi.ps.201300348  1
2014 Hayashi-Takagi A, Araki Y, Nakamura M, Vollrath B, Duron SG, Yan Z, Kasai H, Huganir RL, Campbell DA, Sawa A. PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence. Proceedings of the National Academy of Sciences of the United States of America. 111: 6461-6. PMID 24706880 DOI: 10.1073/pnas.1321109111  1
2014 Emiliani FE, Sedlak TW, Sawa A. Oxidative stress and schizophrenia: recent breakthroughs from an old story. Current Opinion in Psychiatry. 27: 185-90. PMID 24613987 DOI: 10.1097/YCO.0000000000000054  1
2014 Coughlin JM, Wang Y, Ma S, Yue C, Kim PK, Adams AV, Roosa HV, Gage KL, Stathis M, Rais R, Rojas C, McGlothan JL, Watkins CC, Sacktor N, Guilarte TR, ... ... Sawa A, et al. Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV. Journal of Neurovirology. 20: 219-32. PMID 24567030 DOI: 10.1007/s13365-014-0239-5  1
2014 Posporelis S, Sawa A, Smith GS, Stitzer ML, Lyketsos CG, Chisolm MS. Promoting careers in academic research to psychiatry residents. Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry. 38: 185-90. PMID 24497181 DOI: 10.1007/s40596-014-0037-7  1
2014 Porteous DJ, Thomson PA, Millar JK, Evans KL, Hennah W, Soares DC, McCarthy S, McCombie WR, Clapcote SJ, Korth C, Brandon NJ, Sawa A, Kamiya A, Roder JC, Lawrie SM, et al. DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan. Molecular Psychiatry. 19: 141-3. PMID 24457522 DOI: 10.1038/mp.2013.160  1
2014 Watkins CC, Sawa A, Pomper MG. Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application. Translational Psychiatry. 4: e350. PMID 24448212 DOI: 10.1038/tp.2013.119  1
2014 Brennand KJ, Landek-Salgado MA, Sawa A. Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells. Biological Psychiatry. 75: 936-44. PMID 24331955 DOI: 10.1016/j.biopsych.2013.10.025  1
2014 Wei J, Graziane NM, Wang H, Zhong P, Wang Q, Liu W, Hayashi-Takagi A, Korth C, Sawa A, Brandon NJ, Yan Z. Regulation of N-methyl-D-aspartate receptors by disrupted-in-schizophrenia-1. Biological Psychiatry. 75: 414-24. PMID 23906531 DOI: 10.1016/j.biopsych.2013.06.009  1
2014 Miyazaki K, Shibuya K, Suzuki M, Wado H, Sawa A. Correlation between thermal hysteresis width and broadening of metal-insulator transition in Cr- and Nb-doped VO2 films Japanese Journal of Applied Physics. 53. DOI: 10.7567/JJAP.53.071102  0.36
2014 Kubota M, Yamada H, Nakao H, Okamoto J, Yamasaki Y, Sawa A, Murakami Y. Magnetic and electronic properties of (LaMnO3) 5(SrMnO3)5 superlattice revealed by resonant soft X-ray scattering Japanese Journal of Applied Physics. 53. DOI: 10.7567/JJAP.53.05FH07  0.36
2014 Shibuya K, Sawa A. Epitaxial growth and structural transition of VO2/MgF 2(001) Japanese Journal of Applied Physics. 53. DOI: 10.7567/JJAP.53.05FF03  0.36
2014 Shibata G, Yoshimatsu K, Sakai E, Singh VR, Verma VK, Ishigami K, Harano T, Kadono T, Takeda Y, Okane T, Saitoh Y, Yamagami H, Sawa A, Kumigashira H, Oshima M, et al. Thickness-dependent ferromagnetic metal to paramagnetic insulator transition in La0.6 Sr0.4 MnO3 thin films studied by x-ray magnetic circular dichroism Physical Review B - Condensed Matter and Materials Physics. 89. DOI: 10.1103/PhysRevB.89.235123  0.36
2014 Okamoto J, Nakao H, Yamasaki Y, Sudayama T, Kobayashi K, Takahashi Y, Yamada H, Sawa A, Kubota M, Kumai R, Murakami Y. Construction of a soft X-ray diffractometer with a 7.5-T superconducting magnet Journal of Physics: Conference Series. 502. DOI: 10.1088/1742-6596/502/1/012016  0.36
2014 Miranda E, Jiménez D, Tsurumaki-Fukuchi A, Blasco J, Yamada H, Suñé J, Sawa A. Modeling of hysteretic Schottky diode-like conduction in Pt/BiFeO 3/SrRuO3 switches Applied Physics Letters. 105. DOI: 10.1063/1.4894116  0.36
2014 Tsurumaki-Fukuchi A, Yamada H, Sawa A. Resistive switching characteristics in dielectric/ferroelectric composite devices improved by post-thermal annealing at relatively low temperature Applied Physics Letters. 104. DOI: 10.1063/1.4867260  0.36
2014 Matsuzaki H, Matsui Y, Uchida R, Yada H, Terashige T, Li BS, Sawa A, Kawasaki M, Tokura Y, Okamoto H. Photocarrier dynamics in anatase TiO2 investigated by pump-probe absorption spectroscopy Journal of Applied Physics. 115. DOI: 10.1063/1.4864219  0.36
2014 Nakao H, Yamada H, Sawa A, Iwasa K, Okamoto J, Sudayama T, Yamasaki Y, Murakami Y. Neutron magnetic scattering study in manganite thin film system Solid State Communications. 185: 18-20. DOI: 10.1016/j.ssc.2014.01.019  0.36
2014 Cascella NG, Sawa A. The Claustrum in Schizophrenia The Claustrum: Structural, Functional, and Clinical Neuroscience. 237-243. DOI: 10.1016/B978-0-12-404566-8.00009-X  1
2014 Zoubovsky SP, Sawa A, Brandon NJ. Emerging Role for PDE4 in Neuropsychiatric Disorders: Translating Advances from Genetic Studies Into Relevant Therapeutic Strategies Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery. 211-222. DOI: 10.1002/9781118836507.ch08  1
2013 Takayanagi Y, Gerner G, Takayanagi M, Rao V, Vannorsdall TD, Sawa A, Schretlen DJ, Cascella NG. Hippocampal volume reduction correlates with apathy in traumatic brain injury, but not schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences. 25: 292-301. PMID 24247856 DOI: 10.1176/appi.neuropsych.12040093  1
2013 Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders. Neuroscience Research. 77: 247-50. PMID 24120685 DOI: 10.1016/j.neures.2013.09.010  1
2013 Toritsuka M, Kimoto S, Muraki K, Landek-Salgado MA, Yoshida A, Yamamoto N, Horiuchi Y, Hiyama H, Tajinda K, Keni N, Illingworth E, Iwamoto T, Kishimoto T, Sawa A, Tanigaki K. Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model. Proceedings of the National Academy of Sciences of the United States of America. 110: 17552-7. PMID 24101523 DOI: 10.1073/pnas.1312661110  1
2013 Takayanagi M, Wentz J, Takayanagi Y, Schretlen DJ, Ceyhan E, Wang L, Suzuki M, Sawa A, Barta PE, Ratnanather JT, Cascella NG. Reduced anterior cingulate gray matter volume and thickness in subjects with deficit schizophrenia. Schizophrenia Research. 150: 484-90. PMID 24035178 DOI: 10.1016/j.schres.2013.07.036  1
2013 Takayanagi Y, Cascella NG, Santora D, Gregory PE, Sawa A, Eaton WW. Relationships between serum leptin level and severity of positive symptoms in schizophrenia. Neuroscience Research. 77: 97-101. PMID 23896201 DOI: 10.1016/j.neures.2013.07.003  1
2013 Tezuka T, Tamura M, Kondo MA, Sakaue M, Okada K, Takemoto K, Fukunari A, Miwa K, Ohzeki H, Kano S, Yasumatsu H, Sawa A, Kajii Y. Cuprizone short-term exposure: astrocytic IL-6 activation and behavioral changes relevant to psychosis. Neurobiology of Disease. 59: 63-8. PMID 23867234 DOI: 10.1016/j.nbd.2013.07.003  1
2013 Johnson AW, Jaaro-Peled H, Shahani N, Sedlak TW, Zoubovsky S, Burruss D, Emiliani F, Sawa A, Gallagher M. Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness. Proceedings of the National Academy of Sciences of the United States of America. 110: 12462-7. PMID 23840059 DOI: 10.1073/pnas.1307925110  1
2013 Kannan G, Sawa A, Pletnikov MV. Mouse models of gene-environment interactions in schizophrenia. Neurobiology of Disease. 57: 5-11. PMID 23748077 DOI: 10.1016/j.nbd.2013.05.012  1
2013 Soda T, Frank C, Ishizuka K, Baccarella A, Park YU, Flood Z, Park SK, Sawa A, Tsai LH. DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. Molecular Psychiatry. 18: 898-908. PMID 23587879 DOI: 10.1038/mp.2013.38  1
2013 Kondo MA, Tajinda K, Colantuoni C, Hiyama H, Seshadri S, Huang B, Pou S, Furukori K, Hookway C, Jaaro-Peled H, Kano SI, Matsuoka N, Harada K, Ni K, Pevsner J, ... Sawa A, et al. Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control. Translational Psychiatry. 3: e243. PMID 23549417 DOI: 10.1038/tp.2013.19  1
2013 Mor E, Kano S, Colantuoni C, Sawa A, Navon R, Shomron N. MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients. Neurobiology of Disease. 55: 1-10. PMID 23542694 DOI: 10.1016/j.nbd.2013.03.011  1
2013 Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano S, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, et al. Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia. 61: 679-93. PMID 23382131 DOI: 10.1002/glia.22461  1
2013 Xiang PH, Asanuma S, Yamada H, Sato H, Inoue IH, Akoh H, Sawa A, Kawasaki M, Iwasa Y. Electrolyte-gated SmCoO3 thin-film transistors exhibiting thickness-dependent large switching ratio at room temperature. Advanced Materials (Deerfield Beach, Fla.). 25: 2158-61. PMID 23382006 DOI: 10.1002/adma.201204505  0.36
2013 Sakurai T, Shinobu LA, Sawa A. Schizophrenia research in 2013: are we making progress? Neurobiology of Disease. 53: 1-2. PMID 23380149 DOI: 10.1016/j.nbd.2013.01.021  1
2013 Seshadri S, Zeledon M, Sawa A. Synapse-specific contributions in the cortical pathology of schizophrenia. Neurobiology of Disease. 53: 26-35. PMID 23336981 DOI: 10.1016/j.nbd.2013.01.009  1
2013 Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, Kano S, Ozaki N, Nabeshima T, Sawa A. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science (New York, N.Y.). 339: 335-9. PMID 23329051 DOI: 10.1126/science.1226931  1
2013 Jaaro-Peled H, Niwa M, Foss CA, Murai R, de Los Reyes S, Kamiya A, Mateo Y, O'Donnell P, Cascella NG, Nabeshima T, Guilarte TR, Pomper MG, Sawa A. Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging. Human Molecular Genetics. 22: 1574-80. PMID 23314019 DOI: 10.1093/hmg/ddt007  1
2013 Narayan S, Nakajima K, Sawa A. DISC1: a key lead in studying cortical development and associated brain disorders. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 19: 451-64. PMID 23300216 DOI: 10.1177/1073858412470168  1
2013 Kano S, Colantuoni C, Han F, Zhou Z, Yuan Q, Wilson A, Takayanagi Y, Lee Y, Rapoport J, Eaton W, Cascella N, Ji H, Goldman D, Sawa A. Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia. Molecular Psychiatry. 18: 740-2. PMID 22925834 DOI: 10.1038/mp.2012.120  1
2013 Ma TM, Abazyan S, Abazyan B, Nomura J, Yang C, Seshadri S, Sawa A, Snyder SH, Pletnikov MV. Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion. Molecular Psychiatry. 18: 557-67. PMID 22801410 DOI: 10.1038/mp.2012.97  1
2013 Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A. Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Molecular Psychiatry. 18: 10-1. PMID 22349781 DOI: 10.1038/mp.2012.6  1
2013 Ahn JK, Akikawa H, Aoki S, Arai K, Bahk SY, Baik KM, Bassalleck B, Chung JH, Chung MS, Davis DH, Fukuda T, Hoshino K, Ichikawa A, Ieiri M, Imai K, ... ... Sawa A, et al. Double-Λ hypernuclei observed in a hybrid emulsion experiment Physical Review C - Nuclear Physics. 88. DOI: 10.1103/PhysRevC.88.014003  1
2013 Jiménez D, Miranda E, Tsurumaki-Fukuchi A, Yamada H, Suñé J, Sawa A. Multilevel recording in Bi-deficient Pt/BFO/SRO heterostructures based on ferroelectric resistive switching targeting high-density information storage in nonvolatile memories Applied Physics Letters. 103. DOI: 10.1063/1.4855155  0.36
2013 Tsurumaki-Fukuchi A, Yamada H, Sawa A. Resistive switching artificially induced in a dielectric/ferroelectric composite diode Applied Physics Letters. 103. DOI: 10.1063/1.4824214  0.36
2013 Shibuya K, Tsutsumi J, Hasegawa T, Sawa A. Fabrication and Raman scattering study of epitaxial VO2 films on MgF2 (001) substrates Applied Physics Letters. 103. DOI: 10.1063/1.4813442  0.36
2013 Harano T, Shibata G, Ishigami K, Takashashi Y, Verma VK, Singh VR, Kadono T, Fujimori A, Takeda Y, Okane T, Saitoh Y, Yamagami H, Koide T, Yamada H, Sawa A, et al. Role of doped Ru in coercivity-enhanced La0.6Sr 0.4MnO3 thin film studied by x-ray magnetic circular dichroism Applied Physics Letters. 102. DOI: 10.1063/1.4808090  0.36
2013 Li BS, Sawa A, Okamoto H. Fermi level shift in La2-xSrxCuO4 probed by heteroepitaxial junctions with Nb-doped SrTiO3 Applied Physics Letters. 102. DOI: 10.1063/1.4798252  0.36
2012 Hikida T, Gamo NJ, Sawa A. DISC1 as a therapeutic target for mental illnesses. Expert Opinion On Therapeutic Targets. 16: 1151-60. PMID 23130881 DOI: 10.1517/14728222.2012.719879  1
2012 Takayanagi Y, Cascella NG, Sawa A, Eaton WW. Diabetes is associated with lower global cognitive function in schizophrenia. Schizophrenia Research. 142: 183-7. PMID 23031192 DOI: 10.1016/j.schres.2012.08.034  1
2012 Terrin A, Monterisi S, Stangherlin A, Zoccarato A, Koschinski A, Surdo NC, Mongillo M, Sawa A, Jordanides NE, Mountford JC, Zaccolo M. PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome. The Journal of Cell Biology. 198: 607-21. PMID 22908311 DOI: 10.1083/jcb.201201059  1
2012 Rais R, Thomas AG, Wozniak K, Wu Y, Jaaro-Peled H, Sawa A, Strick CA, Engle SJ, Brandon NJ, Rojas C, Slusher BS, Tsukamoto T. Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 2067-73. PMID 22837388 DOI: 10.1124/dmd.112.046482  1
2012 Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, García Á, Requena JR, Hipolito M, Rai N, et al. Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Human Molecular Genetics. 21: 4406-18. PMID 22798627 DOI: 10.1093/hmg/dds273  1
2012 Golzio C, Willer J, Talkowski ME, Oh EC, Taniguchi Y, Jacquemont S, Reymond A, Sun M, Sawa A, Gusella JF, Kamiya A, Beckmann JS, Katsanis N. KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant. Nature. 485: 363-7. PMID 22596160 DOI: 10.1038/nature11091  1
2012 Yang X, Ewald ER, Huo Y, Tamashiro KL, Salvatori R, Sawa A, Wand GS, Lee RS. Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5. Biochemical and Biophysical Research Communications. 420: 570-5. PMID 22445894 DOI: 10.1016/j.bbrc.2012.03.035  1
2012 Lin CY, Sawa A, Jaaro-Peled H. Better understanding of mechanisms of schizophrenia and bipolar disorder: from human gene expression profiles to mouse models. Neurobiology of Disease. 45: 48-56. PMID 21914480 DOI: 10.1016/j.nbd.2011.08.025  1
2012 Shahani N, Sawa A. Protein S-nitrosylation: role for nitric oxide signaling in neuronal death. Biochimica Et Biophysica Acta. 1820: 736-42. PMID 21803124 DOI: 10.1016/j.bbagen.2011.07.010  1
2012 Mouri A, Koseki T, Narusawa S, Niwa M, Mamiya T, Kano S, Sawa A, Nabeshima T. Mouse strain differences in phencyclidine-induced behavioural changes. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 767-79. PMID 21733237 DOI: 10.1017/S146114571100085X  1
2012 Taniguchi Y, Young-Pearse T, Sawa A, Kamiya A. In utero electroporation as a tool for genetic manipulation in vivo to study psychiatric disorders: from genes to circuits and behaviors. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 18: 169-79. PMID 21551077 DOI: 10.1177/1073858411399925  1
2012 Tsurumaki-Fukuchi A, Yamada H, Sawa A. Resistive switching memory based on ferroelectric polarization reversal at schottky-like BiFeO3 Interfaces Materials Research Society Symposium Proceedings. 1430: 99-104. DOI: 10.1557/opl.2012.933  0.36
2012 Xiang PH, Yamada H, Akoh H, Sawa A. Phase diagrams of strained Ca1-xCexMnO3 films Journal of Applied Physics. 112. DOI: 10.1063/1.4768198  0.36
2012 Tsurumaki A, Yamada H, Sawa A. Impact of Bi deficiencies on ferroelectric resistive switching characteristics observed at p-type schottky-like Pt/Bi 1-δFeO 3 interfaces Advanced Functional Materials. 22: 1040-1047. DOI: 10.1002/adfm.201102883  0.36
2011 Kondo M, Sawa A. Anti-/Propsychotic drug signaling via heteromeric GPCRs--a balancing act? Cell. 147: 964-5. PMID 22118451 DOI: 10.1016/j.cell.2011.11.012  1
2011 Xiang PH, Asanuma S, Yamada H, Inoue IH, Sato H, Akoh H, Sawa A, Ueno K, Yuan H, Shimotani H, Kawasaki M, Iwasa Y. Strain-mediated phase control and electrolyte-gating of electron-doped manganites. Advanced Materials (Deerfield Beach, Fla.). 23: 5822-7. PMID 22105844 DOI: 10.1002/adma.201102968  0.36
2011 Brandon NJ, Sawa A. Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nature Reviews. Neuroscience. 12: 707-22. PMID 22095064 DOI: 10.1038/nrn3120  1
2011 Mitchell KJ, Huang ZJ, Moghaddam B, Sawa A. Following the genes: a framework for animal modeling of psychiatric disorders. Bmc Biology. 9: 76. PMID 22078115 DOI: 10.1186/1741-7007-9-76  1
2011 Porteous DJ, Millar JK, Brandon NJ, Sawa A. DISC1 at 10: connecting psychiatric genetics and neuroscience. Trends in Molecular Medicine. 17: 699-706. PMID 22015021 DOI: 10.1016/j.molmed.2011.09.002  1
2011 Sattler R, Ayukawa Y, Coddington L, Sawa A, Block D, Chipkin R, Rothstein JD. Human nasal olfactory epithelium as a dynamic marker for CNS therapy development. Experimental Neurology. 232: 203-11. PMID 21945230 DOI: 10.1016/j.expneurol.2011.09.002  1
2011 Cascella NG, Gerner GJ, Fieldstone SC, Sawa A, Schretlen DJ. The insula-claustrum region and delusions in schizophrenia. Schizophrenia Research. 133: 77-81. PMID 21875780 DOI: 10.1016/j.schres.2011.08.004  1
2011 Nagai T, Kitahara Y, Ibi D, Nabeshima T, Sawa A, Yamada K. Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment. Behavioural Brain Research. 225: 305-10. PMID 21835207 DOI: 10.1016/j.bbr.2011.07.049  1
2011 Kano S, Nwulia E, Niwa M, Chen Y, Sawa A, Cascella N. Altered MHC class I expression in dorsolateral prefrontal cortex of nonsmoker patients with schizophrenia. Neuroscience Research. 71: 289-93. PMID 21801761 DOI: 10.1016/j.neures.2011.07.1818  1
2011 Flores R, Hirota Y, Armstrong B, Sawa A, Tomoda T. DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway. Neuroscience Research. 71: 71-7. PMID 21664390 DOI: 10.1016/j.neures.2011.05.014  1
2011 Hayashi-Takagi A, Barker PB, Sawa A. Readdressing synaptic pruning theory for schizophrenia: Combination of brain imaging and cell biology. Communicative & Integrative Biology. 4: 211-2. PMID 21655443 DOI: 10.4161/cib.4.2.14492  1
2011 Nagata E, Saiardi A, Tsukamoto H, Okada Y, Itoh Y, Satoh T, Itoh J, Margolis RL, Takizawa S, Sawa A, Takagi S. Inositol hexakisphosphate kinases induce cell death in Huntington disease. The Journal of Biological Chemistry. 286: 26680-6. PMID 21652713 DOI: 10.1074/jbc.M111.220749  1
2011 Koga M, Serritella AV, Messmer MM, Hayashi-Takagi A, Hester LD, Snyder SH, Sawa A, Sedlak TW. Glutathione is a physiologic reservoir of neuronal glutamate. Biochemical and Biophysical Research Communications. 409: 596-602. PMID 21539809 DOI: 10.1016/j.bbrc.2011.04.087  1
2011 Zoubovsky SP, Pogorelov VM, Taniguchi Y, Kim SH, Yoon P, Nwulia E, Sawa A, Pletnikov MV, Kamiya A. Working memory deficits in neuronal nitric oxide synthase knockout mice: potential impairments in prefrontal cortex mediated cognitive function. Biochemical and Biophysical Research Communications. 408: 707-12. PMID 21539806 DOI: 10.1016/j.bbrc.2011.04.097  1
2011 Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, ... ... Sawa A, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473: 92-6. PMID 21471969 DOI: 10.1038/nature09859  1
2011 Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/pnas.1012621108  1
2011 Ozeki Y, Pickard BS, Kano S, Malloy MP, Zeledon M, Sun DQ, Fujii K, Wakui K, Shirayama Y, Fukushima Y, Kunugi H, Hashimoto K, Muir WJ, Blackwood DH, Sawa A. A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression. Neuroscience Research. 69: 154-60. PMID 20955740 DOI: 10.1016/j.neures.2010.10.003  1
2011 Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, Crozier RA, Revilla-Sanchez R, Kelly MP, Dunlop AJ, Murdoch H, Taylor N, Xie Y, Pausch M, Hayashi-Takagi A, Ishizuka K, ... ... Sawa A, et al. The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Molecular Psychiatry. 16: 1006-23. PMID 20838393 DOI: 10.1038/mp.2010.87  1
2011 Shahani N, Sawa A. Nitric oxide signaling and nitrosative stress in neurons: role for S-nitrosylation. Antioxidants & Redox Signaling. 14: 1493-504. PMID 20812870 DOI: 10.1089/ars.2010.3580  1
2011 Tristan C, Shahani N, Sedlak TW, Sawa A. The diverse functions of GAPDH: views from different subcellular compartments. Cellular Signalling. 23: 317-23. PMID 20727968 DOI: 10.1016/j.cellsig.2010.08.003  1
2011 Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV. Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. Molecular Psychiatry. 16: 293-306. PMID 20048751 DOI: 10.1038/mp.2009.144  1
2011 Li BS, Sawa A, Okamoto H. Suppression of precipitates in the La2-xSrxCuO 4 films grown on LaSrAlO4 substrates by introducing homoepitaxial layer Japanese Journal of Applied Physics. 50. DOI: 10.1143/JJAP.50.093101  0.36
2011 Yada H, Matsubara M, Matsuzaki H, Yamada H, Sawa A, Okamoto H. Discrimination between photodoping- and heat-induced magnetization changes in Nd0.52Sr0.48MnO3 using a heterostructure with SrTiO3 Physical Review B - Condensed Matter and Materials Physics. 84. DOI: 10.1103/PhysRevB.84.045114  0.36
2011 Yada H, Matsubara M, Yamada H, Sawa A, Matsuzaki H, Okamoto H. Ultrafast control of magnetization by photocarrier injection in La 0.9Sr0.1MnO3/SrTiO3 heterostructures Physical Review B - Condensed Matter and Materials Physics. 83. DOI: 10.1103/PhysRevB.83.165408  0.36
2011 Okamoto H, Miyagoe T, Kobayashi K, Uemura H, Nishioka H, Matsuzaki H, Sawa A, Tokura Y. Photoinduced transition from Mott insulator to metal in the undoped cuprates Nd2CuO4 and La2CuO4 Physical Review B - Condensed Matter and Materials Physics. 83. DOI: 10.1103/PhysRevB.83.125102  0.36
2011 Ayhan Y, Jaaro-Peled H, Sawa A, Pletnikov MV. DISC1 mouse models Neuromethods. 59: 211-229. DOI: 10.1007/978-1-61779-157-4_9  1
2010 Abazyan B, Nomura J, Kannan G, Ishizuka K, Tamashiro KL, Nucifora F, Pogorelov V, Ladenheim B, Yang C, Krasnova IN, Cadet JL, Pardo C, Mori S, Kamiya A, Vogel MW, ... Sawa A, et al. Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. Biological Psychiatry. 68: 1172-81. PMID 21130225 DOI: 10.1016/j.biopsych.2010.09.022  1
2010 Young-Pearse TL, Suth S, Luth ES, Sawa A, Selkoe DJ. Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10431-40. PMID 20685985 DOI: 10.1523/JNEUROSCI.1445-10.2010  1
2010 Lipina TV, Niwa M, Jaaro-Peled H, Fletcher PJ, Seeman P, Sawa A, Roder JC. Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia. Genes, Brain, and Behavior. 9: 777-89. PMID 20618446 DOI: 10.1111/j.1601-183X.2010.00615.x  1
2010 Hayashi MA, Guerreiro JR, Charych E, Kamiya A, Barbosa RL, Machado MF, Campeiro JD, Oliveira V, Sawa A, Camargo AC, Brandon NJ. Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth. Molecular and Cellular Neurosciences. 44: 353-61. PMID 20462516 DOI: 10.1016/j.mcn.2010.04.006  1
2010 Cascella NG, Fieldstone SC, Rao VA, Pearlson GD, Sawa A, Schretlen DJ. Gray-matter abnormalities in deficit schizophrenia. Schizophrenia Research. 120: 63-70. PMID 20452187 DOI: 10.1016/j.schres.2010.03.039  1
2010 Hayashi-Takagi A, Sawa A. Disturbed synaptic connectivity in schizophrenia: convergence of genetic risk factors during neurodevelopment. Brain Research Bulletin. 83: 140-6. PMID 20433911 DOI: 10.1016/j.brainresbull.2010.04.007  1
2010 Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/pnas.0909284107  1
2010 Niwa M, Kamiya A, Murai R, Kubo K, Gruber AJ, Tomita K, Lu L, Tomisato S, Jaaro-Peled H, Seshadri S, Hiyama H, Huang B, Kohda K, Noda Y, O'Donnell P, ... ... Sawa A, et al. Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron. 65: 480-9. PMID 20188653 DOI: 10.1016/j.neuron.2010.01.019  1
2010 Tajinda K, Ishizuka K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Neuronal biomarkers from patients with mental illnesses: a novel method through nasal biopsy combined with laser-captured microdissection. Molecular Psychiatry. 15: 231-2. PMID 20168323 DOI: 10.1038/mp.2009.73  1
2010 Schretlen DJ, Vannorsdall TD, Winicki JM, Mushtaq Y, Hikida T, Sawa A, Yolken RH, Dickerson FB, Cascella NG. Neuroanatomic and cognitive abnormalities related to herpes simplex virus type 1 in schizophrenia. Schizophrenia Research. 118: 224-31. PMID 20153952 DOI: 10.1016/j.schres.2010.01.008  1
2010 Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, Dunlop AJ, Makino Y, Seshadri AJ, Ishizuka K, Srivastava DP, Xie Z, Baraban JM, Houslay MD, Tomoda T, Brandon NJ, ... ... Sawa A, et al. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nature Neuroscience. 13: 327-32. PMID 20139976 DOI: 10.1038/nn.2487  1
2010 Ou XM, Stockmeier CA, Meltzer HY, Overholser JC, Jurjus GJ, Dieter L, Chen K, Lu D, Johnson C, Youdim MB, Austin MC, Luo J, Sawa A, May W, Shih JC. A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. Biological Psychiatry. 67: 855-63. PMID 20022592 DOI: 10.1016/j.biopsych.2009.10.032  1
2010 Jaaro-Peled H, Ayhan Y, Pletnikov MV, Sawa A. Review of pathological hallmarks of schizophrenia: comparison of genetic models with patients and nongenetic models. Schizophrenia Bulletin. 36: 301-13. PMID 19903746 DOI: 10.1093/schbul/sbp133  1
2010 Ishizuka K, Tajinda K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Negative symptoms of schizophrenia correlate with impairment on the University of Pennsylvania smell identification test. Neuroscience Research. 66: 106-10. PMID 19819272 DOI: 10.1016/j.neures.2009.10.001  1
2010 Ibi D, Nagai T, Koike H, Kitahara Y, Mizoguchi H, Niwa M, Jaaro-Peled H, Nitta A, Yoneda Y, Nabeshima T, Sawa A, Yamada K. Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood. Behavioural Brain Research. 206: 32-7. PMID 19716847 DOI: 10.1016/j.bbr.2009.08.027  1
2010 Konoto M, Fukushima A, Matsumoto R, Kubota H, Yakushiji K, Sawa A, Yuasa S, Ando K. Direct imaging of local spin orientation within artificial nanomagnets Applied Physics Express. 3. DOI: 10.1143/APEX.3.063001  0.36
2010 Nakamura M, Sawa A, Fujioka J, Kawasaki M, Tokura Y. Interface band profiles of Mott-insulator/Nb: SrTiO3 heterojunctions as investigated by optical spectroscopy Physical Review B - Condensed Matter and Materials Physics. 82. DOI: 10.1103/PhysRevB.82.201101  0.36
2010 Okamoto H, Miyagoe T, Kobayashi K, Uemura H, Nishioka H, Matsuzaki H, Sawa A, Tokura Y. Ultrafast charge dynamics in photoexcited Nd2 CuO4 and La2 CuO4 cuprate compounds investigated by femtosecond absorption spectroscopy Physical Review B - Condensed Matter and Materials Physics. 82. DOI: 10.1103/PhysRevB.82.060513  0.36
2010 Yamada H, Xiang PH, Sawa A. Phase evolution and critical behavior in strain-tuned LaMnO3 -SrMnO3 superlattices Physical Review B - Condensed Matter and Materials Physics. 81. DOI: 10.1103/PhysRevB.81.014410  0.36
2010 Asanuma S, Xiang PH, Yamada H, Sato H, Inoue IH, Akoh H, Sawa A, Ueno K, Shimotani H, Yuan H, Kawasaki M, Iwasa Y. Tuning of the metal-insulator transition in electrolyte-gated NdNiO 3 thin films Applied Physics Letters. 97. DOI: 10.1063/1.3496458  0.36
2010 Xiang PH, Asanuma S, Yamada H, Inoue IH, Akoh H, Sawa A. Room temperature Mott metal-insulator transition and its systematic control in Sm1-xCaxNiO3 thin films Applied Physics Letters. 97. DOI: 10.1063/1.3467199  0.36
2010 Xiang PH, Yamada H, Sawa A, Akoh H. Colossal magnetoresistance accompanied with magnetorelaxor behavior in phase-separated Ca1-x Cex MnO3 thin films and CaMnO3 / Ca0.92 Ce0.08 MnO3 superlattices Journal of Applied Physics. 107. DOI: 10.1063/1.3353901  0.36
2009 Sawa A. Genetic animal models for schizophrenia: advantages and limitations of genetic manipulation in drosophila, zebrafish, rodents, and primates. Progress in Brain Research. 179: 3-6. PMID 20302812 DOI: 10.1016/S0079-6123(09)17901-3  1
2009 Sawa A. Preface. This volume focuses on how genetic models for schizophrenia, that is, manipulation in genetic susceptibility factors for the disease, have potential in opening a new window of better understanding of etiology-relevant mechanisms. Progress in Brain Research. 179: vii. PMID 19932335 DOI: 10.1016/S0079-6123(09)17919-0  1
2009 Nakajima H, Amano W, Kubo T, Fukuhara A, Ihara H, Azuma YT, Tajima H, Inui T, Sawa A, Takeuchi T. Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death. The Journal of Biological Chemistry. 284: 34331-41. PMID 19837666 DOI: 10.1074/jbc.M109.027698  1
2009 Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A. Understanding the role of DISC1 in psychiatric disease and during normal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12768-75. PMID 19828788 DOI: 10.1523/JNEUROSCI.3355-09.2009  1
2009 Akiyama H, Gotoh A, Shin RW, Koga T, Ohashi T, Sakamoto W, Harada A, Arai H, Sawa A, Uchida C, Uchida T. A novel role for hGas7b in microtubular maintenance: possible implication in tau-associated pathology in Alzheimer disease. The Journal of Biological Chemistry. 284: 32695-9. PMID 19801671 DOI: 10.1074/jbc.M109.035998  1
2009 Jaaro-Peled H, Hayashi-Takagi A, Seshadri S, Kamiya A, Brandon NJ, Sawa A. Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. Trends in Neurosciences. 32: 485-95. PMID 19712980 DOI: 10.1016/j.tins.2009.05.007  1
2009 Sawa A. Cortical development and glutamatergic dysregulation in schizophrenia. Biological Psychiatry. 66: 530-2. PMID 19712774 DOI: 10.1016/j.biopsych.2009.07.016  1
2009 Hsu PC, Nwulia E, Sawa A. Using bioinformatic tools. The American Journal of Psychiatry. 166: 854. PMID 19651749 DOI: 10.1176/appi.ajp.2009.09060908  0.68
2009 Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Aggrawal N, Hester L, Doré S, Snyder SH, Sawa A. GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation. Neuron. 63: 81-91. PMID 19607794 DOI: 10.1016/j.neuron.2009.05.024  1
2009 Ayhan Y, Sawa A, Ross CA, Pletnikov MV. Animal models of gene-environment interactions in schizophrenia. Behavioural Brain Research. 204: 274-81. PMID 19379776 DOI: 10.1016/j.bbr.2009.04.010  1
2009 Cascella NG, Schretlen DJ, Sawa A. Schizophrenia and epilepsy: is there a shared susceptibility? Neuroscience Research. 63: 227-35. PMID 19367784 DOI: 10.1016/j.neures.2009.01.002  1
2009 Sawa A, Cascella NG. Peripheral olfactory system for clinical and basic psychiatry: a promising entry point to the mystery of brain mechanism and biomarker identification in schizophrenia. The American Journal of Psychiatry. 166: 137-9. PMID 19188289 DOI: 10.1176/appi.ajp.2008.08111702  0.68
2009 Asanuma S, Akoh H, Yamada H, Sawa A. Relationship between resistive switching characteristics and band diagrams of Ti/Pr1-x CaxMnO3 junctions Physical Review B - Condensed Matter and Materials Physics. 80. DOI: 10.1103/PhysRevB.80.235113  0.36
2009 Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Hester L, Doré S, Snyder SH, Sawa A. GOSPEL: A Neuroprotective Protein that Binds to GAPDH upon S-Nitrosylation (DOI:10.1016/j.neuron.2009.05.024) Neuron. 63: 709. DOI: 10.1016/j.neuron.2009.08.032  1
2008 Sawamura N, Ando T, Maruyama Y, Fujimuro M, Mochizuki H, Honjo K, Shimoda M, Toda H, Sawamura-Yamamoto T, Makuch LA, Hayashi A, Ishizuka K, Cascella NG, Kamiya A, Ishida N, ... ... Sawa A, et al. Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. Molecular Psychiatry. 13: 1138-48, 1069. PMID 18762802 DOI: 10.1038/mp.2008.101  1
2008 Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, Tsukita S, Pulver AE, Nakajima K, Cascella NG, Katsanis N, Sawa A. Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Archives of General Psychiatry. 65: 996-1006. PMID 18762586 DOI: 10.1001/archpsyc.65.9.996  1
2008 Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nature Cell Biology. 10: 866-73. PMID 18552833 DOI: 10.1038/ncb1747  1
2008 Burdick KE, Kamiya A, Hodgkinson CA, Lencz T, DeRosse P, Ishizuka K, Elashvili S, Arai H, Goldman D, Sawa A, Malhotra AK. Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Human Molecular Genetics. 17: 2462-73. PMID 18469341 DOI: 10.1093/hmg/ddn146  1
2008 Kamiya A, Kitabatake Y, Sawa A. [Neurodevelopmental disturbance in the pathogenesis of major mental disorders]. Brain and Nerve = Shinkei KenkyÅ« No Shinpo. 60: 445-52. PMID 18421986  1
2008 Liu Z, Wang X, Yu Y, Li X, Wang T, Jiang H, Ren Q, Jiao Y, Sawa A, Moran T, Ross CA, Montell C, Smith WW. A Drosophila model for LRRK2-linked parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 105: 2693-8. PMID 18258746 DOI: 10.1073/pnas.0708452105  1
2008 Yasumoto F, Hayashi A, Kamiya A, Negishi T, Yoshikawa Y, Sawa A. Genetic manipulation of brain cultures from the primates: a novel tool for molecular studies of neuropsychiatric disorders. Molecular Psychiatry. 13: 116-8. PMID 18202692 DOI: 10.1038/sj.mp.4002113  1
2008 Hikida T, Mustafa AK, Maeda K, Fujii K, Barrow RK, Saleh M, Huganir RL, Snyder SH, Hashimoto K, Sawa A. Modulation of D-serine levels in brains of mice lacking PICK1. Biological Psychiatry. 63: 997-1000. PMID 18191108 DOI: 10.1016/j.biopsych.2007.09.025  1
2008 Wang Q, Jaaro-Peled H, Sawa A, Brandon NJ. How has DISC1 enabled drug discovery? Molecular and Cellular Neurosciences. 37: 187-95. PMID 18055216 DOI: 10.1016/j.mcn.2007.10.006  1
2007 Oie S, Suenaga S, Sawa A, Kamiya A. Association between isolation sites of methicillin-resistant Staphylococcus aureus (MRSA) in patients with MRSA-positive body sites and MRSA contamination in their surrounding environmental surfaces. Japanese Journal of Infectious Diseases. 60: 367-9. PMID 18032836  0.92
2007 Hashimoto R, Tankou S, Takeda M, Sawa A. Postsynaptic density: a key convergent site for schizophrenia susceptibility factors and possible target for drug development. Drugs of Today (Barcelona, Spain : 1998). 43: 645-54. PMID 17940640 DOI: 10.1358/dot.2007.43.9.1088821  1
2007 Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, ... ... Sawa A, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/sj.mp.4002024  1
2007 Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, Wu D, Xue R, Andradé M, Tankou S, Mori S, Gallagher M, Ishizuka K, Pletnikov M, Kida S, ... Sawa A, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proceedings of the National Academy of Sciences of the United States of America. 104: 14501-6. PMID 17675407 DOI: 10.1073/pnas.0704774104  1
2007 Matsuzawa D, Hashimoto K, Miyatake R, Shirayama Y, Shimizu E, Maeda K, Suzuki Y, Mashimo Y, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada M, ... ... Sawa A, et al. Identification of functional polymorphisms in the promoter region of the human PICK1 gene and their association with methamphetamine psychosis. The American Journal of Psychiatry. 164: 1105-14. PMID 17606663 DOI: 10.1176/appi.ajp.164.7.1105  1
2007 Hashimoto K, Sawa A, Iyo M. Increased levels of glutamate in brains from patients with mood disorders. Biological Psychiatry. 62: 1310-6. PMID 17574216 DOI: 10.1016/j.biopsych.2007.03.017  0.52
2007 Cascella NG, Takaki M, Lin S, Sawa A. Neurodevelopmental involvement in schizophrenia: the olfactory epithelium as an alternative model for research. Journal of Neurochemistry. 102: 587-94. PMID 17488280 DOI: 10.1111/j.1471-4159.2007.4628.x  0.68
2007 Pletnikov MV, Xu Y, Ovanesov MV, Kamiya A, Sawa A, Ross CA. PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation. Neuroscience Research. 58: 234-44. PMID 17418909 DOI: 10.1016/j.neures.2007.03.003  1
2006 Sawamura N, Sawa A. Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses. Annals of the New York Academy of Sciences. 1086: 126-33. PMID 17185511 DOI: 10.1196/annals.1377.018  0.56
2006 Kamiya A, Tomoda T, Chang J, Takaki M, Zhan C, Morita M, Cascio MB, Elashvili S, Koizumi H, Takanezawa Y, Dickerson F, Yolken R, Arai H, Sawa A. DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Human Molecular Genetics. 15: 3313-23. PMID 17035248 DOI: 10.1093/hmg/ddl407  1
2006 Bord L, Wheeler J, Paek M, Saleh M, Lyons-Warren A, Ross CA, Sawamura N, Sawa A. Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history. Neuroscience Research. 56: 286-93. PMID 16965828 DOI: 10.1016/j.neures.2006.07.010  0.72
2006 Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, Mori T, Nemoto K, Adachi N, Izumi A, Chiba S, Noguchi H, Suzuki T, Iwata N, Ozaki N, ... ... Sawa A, et al. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Human Molecular Genetics. 15: 3024-33. PMID 16959794 DOI: 10.1093/hmg/ddl244  1
2006 Maeda K, Nwulia E, Chang J, Balkissoon R, Ishizuka K, Chen H, Zandi P, McInnis MG, Sawa A. Differential expression of disrupted-in-schizophrenia (DISC1) in bipolar disorder. Biological Psychiatry. 60: 929-35. PMID 16814263 DOI: 10.1016/j.biopsych.2006.03.032  1
2006 Ishizuka K, Paek M, Kamiya A, Sawa A. A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions. Biological Psychiatry. 59: 1189-97. PMID 16797264 DOI: 10.1016/j.biopsych.2006.03.065  1
2006 Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC. DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. The Journal of Comparative Neurology. 497: 436-50. PMID 16736468 DOI: 10.1002/cne.21007  1
2006 Hara MR, Cascio MB, Sawa A. GAPDH as a sensor of NO stress. Biochimica Et Biophysica Acta. 1762: 502-9. PMID 16574384 DOI: 10.1016/j.bbadis.2006.01.012  1
2006 Lipska BK, Peters T, Hyde TM, Halim N, Horowitz C, Mitkus S, Weickert CS, Matsumoto M, Sawa A, Straub RE, Vakkalanka R, Herman MM, Weinberger DR, Kleinman JE. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Human Molecular Genetics. 15: 1245-58. PMID 16510495 DOI: 10.1093/hmg/ddl040  1
2006 Hara MR, Thomas B, Cascio MB, Bae BI, Hester LD, Dawson VL, Dawson TM, Sawa A, Snyder SH. Neuroprotection by pharmacologic blockade of the GAPDH death cascade. Proceedings of the National Academy of Sciences of the United States of America. 103: 3887-9. PMID 16505364 DOI: 10.1073/pnas.0511321103  1
2006 Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, Ross CA, Ha HC, Li XJ, Snyder SH, Sawa A. Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proceedings of the National Academy of Sciences of the United States of America. 103: 3405-9. PMID 16492755 DOI: 10.1073/pnas.0511316103  1
2006 Hurt KJ, Sezen SF, Champion HC, Crone JK, Palese MA, Huang PL, Sawa A, Luo X, Musicki B, Snyder SH, Burnett AL. Alternatively spliced neuronal nitric oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America. 103: 3440-3. PMID 16488973 DOI: 10.1073/pnas.0511326103  1
2006 Fujii K, Maeda K, Hikida T, Mustafa AK, Balkissoon R, Xia J, Yamada T, Ozeki Y, Kawahara R, Okawa M, Huganir RL, Ujike H, Snyder SH, Sawa A. Serine racemase binds to PICK1: potential relevance to schizophrenia. Molecular Psychiatry. 11: 150-7. PMID 16314870 DOI: 10.1038/sj.mp.4001776  1
2006 Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM. Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin. Neurobiology of Disease. 21: 381-91. PMID 16150600 DOI: 10.1016/j.nbd.2005.07.014  1
2005 Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, Sawamura N, Park U, Kudo C, Okawa M, Ross CA, Hatten ME, Nakajima K, Sawa A. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nature Cell Biology. 7: 1167-78. PMID 16299498 DOI: 10.1038/ncb1328  1
2005 Sawa A, Snyder SH. Genetics. Two genes link two distinct psychoses. Science (New York, N.Y.). 310: 1128-9. PMID 16293746 DOI: 10.1126/science.1121114  1
2005 Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Human Molecular Genetics. 14: 3801-11. PMID 16239241 DOI: 10.1093/hmg/ddi396  1
2005 Zhang X, Tochigi M, Ohashi J, Maeda K, Kato T, Okazaki Y, Kato N, Tokunaga K, Sawa A, Sasaki T. Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population. Schizophrenia Research. 79: 175-80. PMID 16039834 DOI: 10.1016/j.schres.2005.05.023  0.52
2005 Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A. p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron. 47: 29-41. PMID 15996546 DOI: 10.1016/j.neuron.2005.06.005  1
2005 Lyons-Warren A, Chang JJ, Balkissoon R, Kamiya A, Garant M, Nurnberger J, Scheftner W, Reich T, McMahon F, Kelsoe J, Gershon E, Coryell W, Byerley W, Berrettini W, Depaulo R, ... ... Sawa A, et al. Evidence of association between bipolar disorder and Citron on chromosome 12q24. Molecular Psychiatry. 10: 807-9. PMID 15983625 DOI: 10.1038/sj.mp.4001703  1
2005 Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature Cell Biology. 7: 665-74. PMID 15951807 DOI: 10.1038/ncb1268  1
2005 Sachs NA, Sawa A, Holmes SE, Ross CA, DeLisi LE, Margolis RL. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Molecular Psychiatry. 10: 758-64. PMID 15940305 DOI: 10.1038/sj.mp.4001667  1
2005 Sawa A, Nagata E, Sutcliffe S, Dulloor P, Cascio MB, Ozeki Y, Roy S, Ross CA, Snyder SH. Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblasts. Neurobiology of Disease. 20: 267-74. PMID 15890517 DOI: 10.1016/j.nbd.2005.02.013  1
2005 Sawamura N, Sawamura-Yamamoto T, Ozeki Y, Ross CA, Sawa A. A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proceedings of the National Academy of Sciences of the United States of America. 102: 1187-92. PMID 15657124 DOI: 10.1073/pnas.0406543102  1
2004 Oie S, Ishitobi J, Sawa A, Tomita M, Kamiya A. In vitro bactericidal activity of antimicrobial agents against enterohaemorrhagic Escherichia coli. The Journal of Antimicrobial Chemotherapy. 54: 897-903. PMID 15472004 DOI: 10.1093/jac/dkh442  0.92
2004 Kanai H, Sawa A, Chen RW, Leeds P, Chuang DM. Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons. The Pharmacogenomics Journal. 4: 336-44. PMID 15289798 DOI: 10.1038/sj.tpj.6500269  1
2004 Nagata E, Sawa A, Ross CA, Snyder SH. Autophagosome-like vacuole formation in Huntington's disease lymphoblasts. Neuroreport. 15: 1325-8. PMID 15167559  1
2004 Sawa A, Pletnikov MV, Kamiya A. Neuron-glia interactions clarify genetic-environmental links in mental illness. Trends in Neurosciences. 27: 294-7. PMID 15165731 DOI: 10.1016/j.tins.2004.03.012  1
2004 Ozeki Y, Okawa M, Sawa A. [DISC1 and schizophrenia]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 24: 87-91. PMID 15164617  1
2004 Tsutsumi T, Holmes SE, McInnis MG, Sawa A, Callahan C, DePaulo JR, Ross CA, DeLisi LE, Margolis RL. Novel CAG/CTG repeat expansion mutations do not contribute to the genetic risk for most cases of bipolar disorder or schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 15-9. PMID 14681907 DOI: 10.1002/ajmg.b.20058  1
2003 Oie S, Uematsu T, Sawa A, Mizuno H, Tomita M, Ishida S, Okano Y, Kamiya A. In vitro effects of combinations of antipseudomonal agents against seven strains of multidrug-resistant Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. 52: 911-4. PMID 14585851 DOI: 10.1093/jac/dkg478  0.92
2003 Sawa A, Tomoda T, Bae BI. Mechanisms of neuronal cell death in Huntington's disease. Cytogenetic and Genome Research. 100: 287-95. PMID 14526190  0.8
2003 Sawa A, Kamiya A. Elucidating the pathogenesis of schizophrenia. Bmj (Clinical Research Ed.). 327: 632-3. PMID 14500408 DOI: 10.1136/bmj.327.7416.632  1
2003 Blackshaw S, Eliasson MJ, Sawa A, Watkins CC, Krug D, Gupta A, Arai T, Ferrante RJ, Snyder SH. Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity. Neuroscience. 119: 979-90. PMID 12831857 DOI: 10.1016/S0306-4522(03)00217-3  1
2003 Sawa A, Snyder SH. Schizophrenia: neural mechanisms for novel therapies. Molecular Medicine (Cambridge, Mass.). 9: 3-9. PMID 12765334  1
2003 Igarashi S, Morita H, Bennett KM, Tanaka Y, Engelender S, Peters MF, Cooper JK, Wood JD, Sawa A, Ross CA. Inducible PC12 cell model of Huntington's disease shows toxicity and decreased histone acetylation. Neuroreport. 14: 565-8. PMID 12657886 DOI: 10.1097/01.wnr.0000062604.01019.e1  1
2003 Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A. Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 100: 289-94. PMID 12506198 DOI: 10.1073/pnas.0136913100  1
2003 Nucifora FC, Ellerby LM, Wellington CL, Wood JD, Herring WJ, Sawa A, Hayden MR, Dawson VL, Dawson TM, Ross CA. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity. The Journal of Biological Chemistry. 278: 13047-55. PMID 12464607 DOI: 10.1074/jbc.M211224200  1
2002 Sawa A, Snyder SH. Schizophrenia: diverse approaches to a complex disease. Science (New York, N.Y.). 296: 692-5. PMID 11976442 DOI: 10.1126/science.1070532  1
2001 Luo HR, Saiardi A, Nagata E, Ye K, Yu H, Jung TS, Luo X, Jain S, Sawa A, Snyder SH. GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase. Neuron. 31: 439-51. PMID 11516400  1
2001 Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, L Dawson V, Dawson TM, Ross CA. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Human Molecular Genetics. 10: 919-26. PMID 11309365  1
2001 Saiardi A, Nagata E, Luo HR, Sawa A, Luo X, Snowman AM, Snyder SH. Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate. Proceedings of the National Academy of Sciences of the United States of America. 98: 2306-11. PMID 11226235 DOI: 10.1073/pnas.041614598  1
2000 Takahashi M, Doré S, Ferris CD, Tomita T, Sawa A, Wolosker H, Borchelt DR, Iwatsubo T, Kim SH, Thinakaran G, Sisodia SS, Snyder SH. Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. Neuron. 28: 461-73. PMID 11144356  1
2000 Fang M, Jaffrey SR, Sawa A, Ye K, Luo X, Snyder SH. Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron. 28: 183-93. PMID 11086993  1
2000 Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy The Journal of Clinical Investigation. 106: 803. PMID 10995791  1
2000 Doré S, Goto S, Sampei K, Blackshaw S, Hester LD, Ingi T, Sawa A, Traystman RJ, Koehler RC, Snyder SH. Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia. Neuroscience. 99: 587-92. PMID 10974422 DOI: 10.1016/S0306-4522(00)00216-5  1
2000 Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy. The Journal of Clinical Investigation. 106: 373-84. PMID 10930440 DOI: 10.1172/JCI8273  1
2000 Blackshaw S, Sawa A, Sharp AH, Ross CA, Snyder SH, Khan AA. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1375-9. PMID 10877830  1
1999 Ferris CD, Jaffrey SR, Sawa A, Takahashi M, Brady SD, Barrow RK, Tysoe SA, Wolosker H, Barañano DE, Doré S, Poss KD, Snyder SH. Haem oxygenase-1 prevents cell death by regulating cellular iron. Nature Cell Biology. 1: 152-7. PMID 10559901 DOI: 10.1038/11072  1
1999 Oie S, Sawa A, Kamiya A, Mizuno H. In-vitro effects of a combination of antipseudomonal antibiotics against multi-drug resistant Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. 44: 689-91. PMID 10552987  0.92
1999 Sawa A, Wiegand GW, Cooper J, Margolis RL, Sharp AH, Lawler JF, Greenamyre JT, Snyder SH, Ross CA. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nature Medicine. 5: 1194-8. PMID 10502825 DOI: 10.1038/13518  1
1999 Epner DE, Sawa A, Isaacs JT. Glyceraldehyde-3-phosphate dehydrogenase expression during apoptosis and proliferation of rat ventral prostate. Biology of Reproduction. 61: 687-91. PMID 10456846 DOI: 10.1095/biolreprod61.3.687  1
1998 Conrad C, Amano N, Andreadis A, Xia Y, Namekataf K, Oyama F, Ikeda K, Wakabayashi K, Takahashi H, Thal LJ, Katzman R, Shackelford DA, Matsushita M, Masliah E, Sawa A. Differences in a dinucleotide repeat polymorphism in the tau gene between Caucasian and Japanese populations: implication for progressive supranuclear palsy. Neuroscience Letters. 250: 135-7. PMID 9697937 DOI: 10.1016/S0304-3940(98)00417-0  1
1997 Honda M, Koga E, Ishikawa T, Kobayashi T, Sawa A, Takahashi Y, Honda Y. Alpha-delta sleep in a case with non-24 h sleep-wake syndrome: quantitative electroencephalogram analysis of alpha and delta band waves. Psychiatry and Clinical Neurosciences. 51: 387-92. PMID 9472124  1
1997 Sawa A, Khan AA, Hester LD, Snyder SH. Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death. Proceedings of the National Academy of Sciences of the United States of America. 94: 11669-74. PMID 9326668  1
1997 Sawa A, Amano N, Yamada N, Kajio H, Yagishita S, Takahashi T, Oda M, Arai N, Ikeda K, Tadokoro M, Matsushita M. Apolipoprotein E in progressive supranuclear palsy in Japan. Molecular Psychiatry. 2: 341-2. PMID 9246676  1
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