| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2024 | Faghiri A, Yang K, Faria A, Ishizuka K, Sawa A, Adali T, Calhoun V. Frequency modulation increases the specificity of time-resolved connectivity: A resting-state fMRI study. Network Neuroscience (Cambridge, Mass.). 8: 734-761. PMID 39355435 DOI: 10.1162/netn_a_00372 | 0.445 | |||
| 2024 | Ramos A, Ishizuka K, Hayashida A, Namkung H, Hayes LN, Srivastava R, Zhang M, Kariya T, Elkins N, Palen T, Carloni E, Tsujimura T, Calva C, Ikemoto S, Rais R, ... ... Sawa A, et al. Correction: Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility. Molecular Psychiatry. PMID 38956375 DOI: 10.1038/s41380-024-02636-z | 0.776 | |||
| 2024 | Fry BR, Fex V, Sawa A, Niwa M, Johnson AW. The role of midbrain dopamine cells projecting to the insular cortex in mediated performance: Implications for animal models of reality testing. Behavioral Neuroscience. 138: 164-177. PMID 38934920 DOI: 10.1037/bne0000580 | 0.644 | |||
| 2024 | Niwa M, Lockhart S, Wood DJ, Yang K, Francis-Oliveira J, Kin K, Ahmed A, Wand GS, Kano SI, Payne JL, Sawa A. Prolonged HPA axis dysregulation in postpartum depression associated with adverse early life experiences: A cross-species translational study. Nature. Mental Health. 2: 593-604. PMID 38736646 DOI: 10.1038/s44220-024-00217-1 | 0.758 | |||
| 2024 | Ramos A, Ishizuka K, Hayashida A, Namkung H, Hayes LN, Srivastava R, Zhang M, Kariya T, Elkins N, Palen T, Carloni E, Tsujimura T, Calva C, Ikemoto S, Rais R, ... ... Sawa A, et al. Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility. Molecular Psychiatry. PMID 38615102 DOI: 10.1038/s41380-024-02553-1 | 0.794 | |||
| 2024 | Mihaljevic M, Nagpal A, Etyemez S, Narita Z, Ross A, Schaub R, Cascella NG, Coughlin JM, Nestadt G, Nucifora FC, Sedlak TW, Calhoun VD, Faria AV, Yang K, Sawa A. Neuroimaging alterations and relapse in early-stage psychosis. Journal of Psychiatry & Neuroscience : Jpn. 49: E135-E142. PMID 38569725 DOI: 10.1503/jpn.230115 | 0.573 | |||
| 2024 | Mihaljevic M, Chang YH, Witmer AM, Coughlin JM, Schretlen DJ, Barker PB, Yang K, Sawa A. Reduction of N-acetyl aspartate (NAA) in association with relapse in early-stage psychosis: a 7-Tesla MRS study. Schizophrenia (Heidelberg, Germany). 10: 29. PMID 38429320 DOI: 10.1038/s41537-024-00451-7 | 0.601 | |||
| 2024 | Jensen KM, Calhoun VD, Fu Z, Yang K, Faria AV, Ishizuka K, Sawa A, Andrés-Camazón P, Coffman BA, Seebold D, Turner JA, Salisbury DF, Iraji A. A whole-brain neuromark resting-state fMRI analysis of first-episode and early psychosis: Evidence of aberrant cortical-subcortical-cerebellar functional circuitry. Neuroimage. Clinical. 41: 103584. PMID 38422833 DOI: 10.1016/j.nicl.2024.103584 | 0.516 | |||
| 2024 | Yang K, Hasegawa Y, Bhattarai JP, Hua J, Dower M, Etyemez S, Prasad N, Duvall L, Paez A, Smith A, Wang Y, Zhang YF, Lane AP, Ishizuka K, Kamath V, ... ... Sawa A, et al. Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders. Molecular Psychiatry. PMID 38321120 DOI: 10.1038/s41380-024-02425-8 | 0.678 | |||
| 2023 | Hasegawa Y, Kim J, Ursini G, Jouroukhin Y, Zhu X, Miyahara Y, Xiong F, Madireddy S, Obayashi M, Lutz B, Sawa A, Brown SP, Pletnikov MV, Kamiya A. Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication. Nature Communications. 14: 6559. PMID 37880248 DOI: 10.1038/s41467-023-42276-5 | 0.519 | |||
| 2023 | Hasegawa Y, Kim J, Ursini G, Jouroukhin Y, Zhu X, Miyahara Y, Xiong F, Madireddy S, Obayashi M, Lutz B, Sawa A, Brown SP, Pletnikov MV, Kamiya A. Microglial cannabinoid receptor type 1 mediates social memory deficits produced by adolescent THC exposure and 16p11.2 duplication. Biorxiv : the Preprint Server For Biology. PMID 37546830 DOI: 10.1101/2023.07.24.550212 | 0.511 | |||
| 2023 | Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Sawa A, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w | 0.401 | |||
| 2023 | Mihaljevic M, Lam M, Ayala-Grosso C, Davis-Batt F, Schretlen DJ, Ishizuka K, Yang K, Sawa A. Olfactory neuronal cells as a promising tool to realize the "druggable genome" approach for drug discovery in neuropsychiatric disorders. Frontiers in Neuroscience. 16: 1081124. PMID 36967982 DOI: 10.3389/fnins.2022.1081124 | 0.508 | |||
| 2023 | Merritt K, McCutcheon RA, Aleman A, Ashley S, Beck K, Block W, Bloemen OJN, Borgan F, Boules C, Bustillo JR, Capizzano AA, Coughlin JM, David A, de la Fuente-Sandoval C, Demjaha A, ... ... Sawa A, et al. Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis. Molecular Psychiatry. PMID 36806762 DOI: 10.1038/s41380-023-01991-7 | 0.591 | |||
| 2023 | Wang M, Barker PB, Cascella NG, Coughlin JM, Nestadt G, Nucifora FC, Sedlak TW, Kelly A, Younes L, Geman D, Palaniyappan L, Sawa A, Yang K. Longitudinal changes in brain metabolites in healthy controls and patients with first episode psychosis: a 7-Tesla MRS study. Molecular Psychiatry. PMID 36732587 DOI: 10.1038/s41380-023-01969-5 | 0.601 | |||
| 2022 | Hyun JH, Nagahama K, Namkung H, Mignocchi N, Roh SE, Hannan P, Krüssel S, Kwak C, McElroy A, Liu B, Cui M, Lee S, Lee D, Huganir RL, Worley PF, ... Sawa A, et al. Tagging active neurons by soma-targeted Cal-Light. Nature Communications. 13: 7692. PMID 36509775 DOI: 10.1038/s41467-022-35406-y | 0.702 | |||
| 2022 | Namkung H, Yukitake H, Fukudome D, Lee BJ, Tian M, Ursini G, Saito A, Lam S, Kannan S, Srivastava R, Niwa M, Sharma K, Zandi P, Jaaro-Peled H, Ishizuka K, ... ... Sawa A, et al. The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder. Neuron. PMID 36379214 DOI: 10.1016/j.neuron.2022.10.031 | 0.793 | |||
| 2022 | Yang K, Hasegawa Y, Hua J, Dower M, Etyemez S, Prasad N, Duvall L, Paez A, Smith A, Lane AP, Ishizuka K, Kamath V, Kamiya A, Sawa A. Immune-related molecular changes in the olfactory epithelium, structural alteration in the olfactory bulb, and psychosis. Biorxiv : the Preprint Server For Biology. PMID 36203543 DOI: 10.1101/2022.09.23.509224 | 0.655 | |||
| 2022 | Hayes LN, An K, Carloni E, Li F, Vincent E, Trippaers C, Paranjpe M, Dölen G, Goff LA, Ramos A, Kano SI, Sawa A. Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry. Nature. PMID 36171283 DOI: 10.1038/s41586-022-05274-z | 0.789 | |||
| 2022 | Kondo M, Norris A, Yang K, Cheshire M, Newkirk I, Chen X, Ishizuka K, Jaffe AE, Sawa A, Pevsner J. Dysfunction of mitochondria and GABAergic interneurons in the anterior cingulate cortex of individuals with schizophrenia. Neuroscience Research. PMID 36162734 DOI: 10.1016/j.neures.2022.09.011 | 0.755 | |||
| 2022 | Kim SH, An K, Namkung H, Saito A, Rannals MD, Moore JR, Mihaljevic M, Saha S, Oh S, Kondo MA, Ishizuka K, Yang K, Maher BJ, Niwa M, Sawa A. Anterior Insula-Associated Social Novelty Recognition: Pivotal Roles of a Local Retinoic Acid Cascade and Oxytocin Signaling. The American Journal of Psychiatry. appiajp21010053. PMID 36128683 DOI: 10.1176/appi.ajp.21010053 | 0.784 | |||
| 2022 | Hasegawa Y, Ma M, Sawa A, Lane AP, Kamiya A. Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology? Translational Psychiatry. 12: 314. PMID 35927242 DOI: 10.1038/s41398-022-02081-y | 0.534 | |||
| 2022 | Etyemez S, Narita Z, Mihaljevic M, Coughlin JM, Nestadt G, Nucifora FCJ, Sedlak TW, Cascella NG, Batt FD, Hua J, Faria A, Ishizuka K, Kamath V, Yang K, Sawa A. Brain regions associated with olfactory dysfunction in first episode psychosis patients. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-9. PMID 35678361 DOI: 10.1080/15622975.2022.2082526 | 0.698 | |||
| 2022 | Patel Y, Shin J, Abé C, Agartz I, Alloza C, Alnæs D, Ambrogi S, Antonucci LA, Arango C, Arolt V, Auzias G, Ayesa-Arriola R, Banaj N, Banaschewski T, Bandeira C, ... ... Sawa A, et al. Virtual Ontogeny of Cortical Growth Preceding Mental Illness. Biological Psychiatry. PMID 35489875 DOI: 10.1016/j.biopsych.2022.02.959 | 0.455 | |||
| 2022 | Jaaro-Peled H, Landek-Salgado MA, Cascella NG, Nucifora FC, Coughlin JM, Nestadt G, Sedlak TW, Lavoie J, De Silva S, Lee S, Tajinda K, Hiyama H, Ishizuka K, Yang K, Sawa A. Sex-specific involvement of the Notch-JAG pathway in social recognition. Translational Psychiatry. 12: 99. PMID 35273151 DOI: 10.1038/s41398-022-01867-4 | 0.801 | |||
| 2022 | Jaaro-Peled H, Kumar S, Hughes D, Sumitomo A, Kim SH, Zoubovsky S, Hirota-Tsuyada Y, Zala D, Bruyere J, Katz BM, Huang B, Flores R, Narayan S, Hou Z, Economides AN, ... ... Sawa A, et al. Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit. Molecular Psychiatry. PMID 35165396 DOI: 10.1038/s41380-021-01389-3 | 0.796 | |||
| 2021 | Namkung H, Thomas KL, Hall J, Sawa A. Parsing neural circuits of fear learning and extinction across basic and clinical neuroscience: towards better translation. Neuroscience and Biobehavioral Reviews. PMID 34921863 DOI: 10.1016/j.neubiorev.2021.12.025 | 0.614 | |||
| 2021 | Xiao MF, Roh SE, Zhou J, Chien CC, Lucey BP, Craig MT, Hayes LN, Coughlin JM, Leweke FM, Jia M, Xu D, Zhou W, Conover Talbot C, Arnold DB, Staley M, ... ... Sawa A, et al. A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function. Science Advances. 7: eabf6935. PMID 34818031 DOI: 10.1126/sciadv.abf6935 | 0.759 | |||
| 2021 | Etyemez S, Narita Z, Mihaljevic M, Ishizuka K, Kamath V, Yang K, Sawa A. Olfactory dysfunction and face processing of social cognition in first-episode psychosis. Neuroscience Research. PMID 34655664 DOI: 10.1016/j.neures.2021.10.003 | 0.474 | |||
| 2021 | Narita Z, Yang K, Kuga H, Piancharoen P, Etyemez S, Faria A, Mihaljevic M, Longo L, Namkung H, Coughlin JM, Nestadt G, Nucifora FC, Sedlak TW, Schaub R, Crawford J, ... ... Sawa A, et al. Face processing of social cognition in patients with first episode psychosis: Its deficits and association with the right subcallosal anterior cingulate cortex. Schizophrenia Research. 238: 99-107. PMID 34649085 DOI: 10.1016/j.schres.2021.09.027 | 0.783 | |||
| 2021 | Yang K, Longo L, Narita Z, Cascella N, Nucifora FC, Coughlin JM, Nestadt G, Sedlak TW, Mihaljevic M, Wang M, Kenkare A, Nagpal A, Sethi M, Kelly A, Di Carlo P, ... ... Sawa A, et al. A multimodal study of a first episode psychosis cohort: potential markers of antipsychotic treatment resistance. Molecular Psychiatry. PMID 34642460 DOI: 10.1038/s41380-021-01331-7 | 0.608 | |||
| 2021 | Kulason S, Ratnanather JT, Miller MI, Kamath V, Hua J, Yang K, Ma M, Ishizuka K, Sawa A. A comparative neuroimaging perspective of olfaction and higher-order olfactory processing: on health and disease. Seminars in Cell & Developmental Biology. PMID 34462249 DOI: 10.1016/j.semcdb.2021.08.009 | 0.516 | |||
| 2021 | Fu X, Shah AP, Keighron J, Mou TM, Ladenheim B, Alt J, Fukudome D, Niwa M, Tamashiro KL, Tanda G, Sawa A, Cadet JL, Rais R, Baraban JM. Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity. Translational Psychiatry. 11: 427. PMID 34392304 DOI: 10.1038/s41398-021-01547-9 | 0.628 | |||
| 2021 | Yang K, Hua J, Etyemez S, Paez A, Prasad N, Ishizuka K, Sawa A, Kamath V. Volumetric alteration of olfactory bulb and immune-related molecular changes in olfactory epithelium in first episode psychosis patients. Schizophrenia Research. 235: 9-11. PMID 34280869 DOI: 10.1016/j.schres.2021.07.016 | 0.442 | |||
| 2021 | Bhattarai JP, Etyemez S, Jaaro-Peled H, Janke E, Leon Tolosa UD, Kamiya A, Gottfried JA, Sawa A, Ma M. Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition. Seminars in Cell & Developmental Biology. PMID 33975755 DOI: 10.1016/j.semcdb.2021.03.022 | 0.736 | |||
| 2021 | Hasegawa Y, Namkung H, Smith A, Sakamoto S, Zhu X, Ishizuka K, Lane AP, Sawa A, Kamiya A. Causal impact of local inflammation in the nasal cavity on higher brain function and cognition. Neuroscience Research. PMID 33932551 DOI: 10.1016/j.neures.2021.04.009 | 0.781 | |||
| 2021 | Merritt K, McGuire PK, Egerton A, Aleman A, Block W, Bloemen OJN, Borgan F, Bustillo JR, Capizzano AA, Coughlin JM, De la Fuente-Sandoval C, Demjaha A, Dempster K, Do KQ, ... ... Sawa A, et al. Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. Jama Psychiatry. PMID 33881460 DOI: 10.1001/jamapsychiatry.2021.0380 | 0.618 | |||
| 2021 | Kano SI, Yang K, Sawa A. Making Sense of Extracellular Vesicles in Body Fluids: Promise and Challenge. Schizophrenia Bulletin. PMID 33748856 DOI: 10.1093/schbul/sbab009 | 0.604 | |||
| 2021 | Li T, Ning B, Kong L, Dai B, He X, Thomas JM, Sawa A, Ross CA, Smith WW. A LRRK2 GTP Binding Inhibitor, 68, Reduces LPS-Induced Signaling Events and TNF-α Release in Human Lymphoblasts. Cells. 10. PMID 33672296 DOI: 10.3390/cells10020480 | 0.404 | |||
| 2021 | Mejias R, Rodriguez-Gotor JJ, Niwa M, Krasnova IN, Adamczyk A, Han M, Thomas GM, Xi ZX, Huganir RL, Pletnikov MV, Sawa A, Cadet JL, Wang T. Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice. Translational Psychiatry. 11: 65. PMID 33462194 DOI: 10.1038/s41398-020-01194-6 | 0.629 | |||
| 2020 | Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, ... Sawa A, et al. PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. Nature Communications. 11: 5903. PMID 33214552 DOI: 10.1038/s41467-020-19637-5 | 0.317 | |||
| 2020 | Takayanagi Y, Ishizuka K, Laursen TM, Yukitake H, Yang K, Cascella NG, Ueda S, Sumitomo A, Narita Z, Horiuchi Y, Niwa M, Taguchi A, White MF, Eaton WW, Mortensen PB, ... ... Sawa A, et al. From population to neuron: exploring common mediators for metabolic problems and mental illnesses. Molecular Psychiatry. PMID 33173197 DOI: 10.1038/s41380-020-00939-5 | 0.713 | |||
| 2020 | Coughlin JM, Yang K, Marsman A, Pradhan S, Wang M, Ward RE, Bonekamp S, Ambinder EB, Higgs CP, Kim PK, Edwards JA, Varvaris M, Wang H, Posporelis S, Ma S, ... ... Sawa A, et al. A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia. Molecular Psychiatry. PMID 33077854 DOI: 10.1038/s41380-020-00901-5 | 0.799 | |||
| 2020 | Sagata N, Kano SI, Ohgidani M, Inamine S, Sakai Y, Kato H, Masuda K, Nakahara T, Nakahara-Kido M, Ohga S, Furue M, Sawa A, Kanba S, Kato TA. Forskolin rapidly enhances neuron-like morphological change of directly induced-neuronal cells from neurofibromatosis type 1 patients. Neuropsychopharmacology Reports. PMID 33037790 DOI: 10.1002/npr2.12144 | 0.686 | |||
| 2020 | Patel Y, Parker N, Shin J, Howard D, French L, Thomopoulos SI, Pozzi E, Abe Y, Abé C, ... ... Sawa A, et al. Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. Jama Psychiatry. PMID 32857118 DOI: 10.1001/Jamapsychiatry.2020.2694 | 0.472 | |||
| 2020 | Shevelkin AV, Terrillion CE, Hasegawa Y, Mychko OA, Jouroukhin Y, Sawa A, Kamiya A, Pletnikov MV. Astrocyte DISC1 contributes to cognitive function in a brain region-dependent manner. Human Molecular Genetics. PMID 32803234 DOI: 10.1093/Hmg/Ddaa180 | 0.6 | |||
| 2020 | Radua J, Vieta E, Shinohara R, Kochunov P, Quidé Y, Green M, Weickert C, Weickert T, Bruggemann J, Kircher T, Nenadic I, Cairns M, Seal M, Schall U, Henskens F, ... ... Sawa A, et al. Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA. Neuroimage. 116956. PMID 32470572 DOI: 10.1016/J.Neuroimage.2020.116956 | 0.526 | |||
| 2020 | Jaaro-Peled H, Sawa A. Neurodevelopmental Factors in Schizophrenia. The Psychiatric Clinics of North America. 43: 263-274. PMID 32439021 DOI: 10.1016/J.Psc.2020.02.010 | 0.722 | |||
| 2020 | Yoshihara Y, Lisi G, Yahata N, Fujino J, Matsumoto Y, Miyata J, Sugihara GI, Urayama SI, Kubota M, Yamashita M, Hashimoto R, Ichikawa N, Cahn W, van Haren NEM, Mori S, ... ... Sawa A, et al. Overlapping but Asymmetrical Relationships Between Schizophrenia and Autism Revealed by Brain Connectivity. Schizophrenia Bulletin. PMID 32300809 DOI: 10.1093/Schbul/Sbaa021 | 0.333 | |||
| 2020 | Delevich K, Jaaro-Peled H, Penzo M, Sawa A, Li B. Parvalbumin interneuron dysfunction in a thalamo-prefrontal cortical circuit in locus impairment mice. Eneuro. PMID 32029441 DOI: 10.1523/ENEURO.0496-19.2020 | 0.703 | |||
| 2020 | Hikida T, Yao S, Macpherson T, Fukakusa A, Morita M, Kimura H, Hirai K, Ando T, Toyoshiba H, Sawa A. Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex. Scientific Reports. 10: 1838. PMID 32020036 DOI: 10.1038/S41598-020-58711-2 | 0.548 | |||
| 2019 | John JP, Thirunavukkarasu P, Ishizuka K, Parekh P, Sawa A. An in-silico approach for discovery of microRNA-TF regulation of DISC1 interactome mediating neuronal migration. Npj Systems Biology and Applications. 5: 17. PMID 32372023 DOI: 10.1038/s41540-019-0094-3 | 0.505 | |||
| 2019 | Narita Z, Stickley A, DeVylder J, Yokoi Y, Inagawa T, Yamada Y, Maruo K, Koyanagi A, Oh H, Sawa A, Sumiyoshi T. Effect of multi-session prefrontal transcranial direct current stimulation on cognition in schizophrenia: A systematic review and meta-analysis. Schizophrenia Research. PMID 31822431 DOI: 10.1016/J.Schres.2019.11.011 | 0.336 | |||
| 2019 | Wen F, Armstrong N, Hou W, Cruz-Cosme R, Obwolo LA, Ishizuka K, Ullah H, Luo MH, Sawa A, Tang Q. Zika virus increases mind bomb 1 levels, causing degradation of pericentriolar material 1 (PCM1) and dispersion of PCM1 granules from the centrosome. The Journal of Biological Chemistry. PMID 31666336 DOI: 10.1074/Jbc.Ra119.010973 | 0.504 | |||
| 2019 | Kano SI, Sawa A. Reply to Brune M and Theiss C: Remaining questions in the relationship between T. gondii infection and major mental illness. Molecular Psychiatry. PMID 31641217 DOI: 10.1038/s41380-019-0556-4 | 0.651 | |||
| 2019 | Tomoda T, Yang K, Sawa A. Neuronal Autophagy in Synaptic Functions and Psychiatric Disorders. Biological Psychiatry. PMID 31542152 DOI: 10.1016/j.biopsych.2019.07.018 | 0.348 | |||
| 2019 | Sakurai T, Sawa A. Editorial for "What can clinical findings tell us about the neurobiology of schizophrenia? Revisited". Neurobiology of Disease. 104521. PMID 31299219 DOI: 10.1016/J.Nbd.2019.104521 | 0.355 | |||
| 2019 | Yang K, Kondo MA, Jaaro-Peled H, Cash-Padgett T, Kano SI, Ishizuka K, Pevsner J, Tomoda T, Sawa A, Niwa M. The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood. Schizophrenia Research. PMID 31204062 DOI: 10.1016/J.Schres.2019.05.032 | 0.824 | |||
| 2019 | Fry BR, Russell N, Gifford R, Robles CF, Manning CE, Sawa A, Niwa M, Johnson AW. Assessing Reality Testing in Mice Through Dopamine-Dependent Associatively Evoked Processing of Absent Gustatory Stimuli. Schizophrenia Bulletin. PMID 31150554 DOI: 10.1093/Schbul/Sbz043 | 0.666 | |||
| 2019 | John JP, Thirunavukkarasu P, Ishizuka K, Parekh P, Sawa A. An in-silico approach for discovery of microRNA-TF regulation of DISC1 interactome mediating neuronal migration. Npj Systems Biology and Applications. 5: 17. PMID 31098296 DOI: 10.1038/s41540-019-0094-3 | 0.505 | |||
| 2019 | Nucifora LG, MacDonald ML, Lee BJ, Peters ME, Norris AL, Orsburn BC, Yang K, Gleason K, Margolis RL, Pevsner J, Tamminga CA, Sweet RA, Ross CA, Sawa A, Nucifora FC. Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia. The American Journal of Psychiatry. appiajp201918070864. PMID 31055969 DOI: 10.1176/Appi.Ajp.2019.18070864 | 0.558 | |||
| 2019 | Mueller FS, Richetto J, Hayes LN, Zambon A, Pollak DD, Sawa A, Meyer U, Weber-Stadlbauer U. Influence of poly(I:C) variability on thermoregulation, immune responses and pregnancy outcomes in mouse models of maternal immune activation. Brain, Behavior, and Immunity. PMID 30980948 DOI: 10.1016/J.Bbi.2019.04.019 | 0.539 | |||
| 2019 | Tharakan R, Kreimer S, Ubaida-Mohien C, Lavoie J, Olexiouk V, Menschaert G, Ingolia NT, Cole RN, Ishizuka K, Sawa A, Nucifora LG. A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics. Neuroscience Research. PMID 30862443 DOI: 10.1016/J.Neures.2019.02.006 | 0.694 | |||
| 2019 | Namkung H, Lee BJ, Sawa A. Causal Inference on Pathophysiological Mediators in Psychiatry. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30850434 DOI: 10.1101/Sqb.2018.83.037655 | 0.681 | |||
| 2019 | Hikida T, Morita M, Kuroiwa M, Macpherson T, Shuto T, Sotogaku N, Niwa M, Sawa A, Nishi A. Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice. Neuroscience Research. PMID 30831136 DOI: 10.1016/J.Neures.2019.02.007 | 0.714 | |||
| 2019 | Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A. Glutathione -transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. Science Signaling. 12. PMID 30783009 DOI: 10.1126/Scisignal.Aar2124 | 0.779 | |||
| 2019 | Sedlak TW, Paul BD, Parker GM, Hester LD, Snowman AM, Taniguchi Y, Kamiya A, Snyder SH, Sawa A. The glutathione cycle shapes synaptic glutamate activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30692251 DOI: 10.1073/Pnas.1817885116 | 0.625 | |||
| 2019 | Wang AM, Pradhan S, Coughlin JM, Trivedi A, DuBois SL, Crawford JL, Sedlak TW, Nucifora FC, Nestadt G, Nucifora LG, Schretlen DJ, Sawa A, Barker PB. Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis. Jama Psychiatry. PMID 30624573 DOI: 10.1001/Jamapsychiatry.2018.3637 | 0.609 | |||
| 2019 | Coughlin J, Du Y, Crawford J, Rubin L, Azad BB, Lesniak WL, Horti A, Schretlen D, Sawa A, Pomper M. 23.4 PET-BASED PRECISION NEUROIMAGING OF THE ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR IN PATIENTS WITH RECENT ONSET OF PSYCHOSIS Schizophrenia Bulletin. 45: S127-S127. DOI: 10.1093/Schbul/Sbz022.094 | 0.583 | |||
| 2019 | Nucifora L, MacDonald M, Lee B, Peters M, Norris A, Orsburn BO, Gleason K, Yang K, Margolis R, Pevsner J, Tamminga C, Sweet R, Ross C, Sawa A, Nucifora F. O2.3. Increased Protein Insolubility In Brains From A Subset Of Patients With Schizophrenia Schizophrenia Bulletin. 45. DOI: 10.1093/Schbul/Sbz021.187 | 0.52 | |||
| 2019 | Nucifora L, MacDonald M, Lee B, Peters M, Norris A, Orsburn B, Yang K, Gleason K, Margolis R, Pevsner J, Tamminga C, Sweet R, Ross C, Sawa A, Nucifora F. F168. Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.705 | 0.521 | |||
| 2018 | Coughlin J, Du Y, Crawford JL, Rubin LH, Behnam Azad B, Lesniak WG, Horti AG, Schretlen DJ, Sawa A, Pomper MG. The availability of the α7 nicotinic acetylcholine receptor in recent-onset psychosis: a study using F-ASEM PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30573639 DOI: 10.2967/Jnumed.118.213686 | 0.602 | |||
| 2018 | Kamath V, Crawford J, DuBois S, Nucifora FC, Nestadt G, Sawa A, Schretlen D. Contributions of olfactory and neuropsychological assessment to the diagnosis of first-episode schizophrenia. Neuropsychology. PMID 30475048 DOI: 10.1037/Neu0000502 | 0.348 | |||
| 2018 | Nucifora FC, Woznica E, Lee BJ, Cascella N, Sawa A. Treatment resistant schizophrenia: Clinical, biological, and therapeutic perspectives. Neurobiology of Disease. PMID 30170114 DOI: 10.1016/j.nbd.2018.08.016 | 0.351 | |||
| 2018 | Kano SI, Hodgkinson CA, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, Choi EY, Chang DJ, Chen Y, Velivela SD, Leister F, Wood J, Chowdari K, Ducci F, Caycedo DA, ... ... Sawa A, et al. Host-parasite interaction associated with major mental illness. Molecular Psychiatry. PMID 30127472 DOI: 10.1038/S41380-018-0217-Z | 0.805 | |||
| 2018 | Sumitomo A, Horike K, Hirai K, Butcher N, Boot E, Sakurai T, Nucifora FC, Bassett AS, Sawa A, Tomoda T. A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia. Science Advances. 4: eaar6637. PMID 30116778 DOI: 10.1126/Sciadv.Aar6637 | 0.325 | |||
| 2018 | Cardarelli RA, Martin R, Jaaro-Peled H, Sawa A, Powell EM, O'Donnell P. Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex. Molecular Neuropsychiatry. 4: 20-29. PMID 29998115 DOI: 10.1159/000488030 | 0.737 | |||
| 2018 | Namkung H, Kim SH, Sawa A. The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology: (Trends in Neuroscience 40, 200-207, 2017). Trends in Neurosciences. PMID 29895478 DOI: 10.1016/J.Tins.2018.05.004 | 0.653 | |||
| 2018 | Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, ... ... Sawa A, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Human Molecular Genetics. PMID 29893844 DOI: 10.1093/Hmg/Ddy219 | 0.794 | |||
| 2018 | Sumitomo A, Saka A, Ueta K, Horike K, Hirai K, Gamo NJ, Hikida T, Nakayama KI, Sawa A, Sakurai T, Tomoda T. Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in -Deficient Mice. Molecular Neuropsychiatry. 3: 223-233. PMID 29888233 DOI: 10.1159/000488081 | 0.782 | |||
| 2018 | Sedlak TW, Nucifora LG, Koga M, Shaffer LS, Higgs C, Tanaka T, Wang AM, Coughlin JM, Barker PB, Fahey JW, Sawa A. Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study. Molecular Neuropsychiatry. 3: 214-222. PMID 29888232 DOI: 10.1159/000487639 | 0.62 | |||
| 2018 | Lockhart S, Sawa A, Niwa M. Developmental trajectories of brain maturation and behavior: Relevance to major mental illnesses. Journal of Pharmacological Sciences. PMID 29773518 DOI: 10.1016/J.Jphs.2018.04.008 | 0.66 | |||
| 2018 | Endo R, Takashima N, Nekooki-Machida Y, Komi Y, Hui KK, Takao M, Akatsu H, Murayama S, Sawa A, Tanaka M. TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration. Biological Psychiatry. PMID 29752072 DOI: 10.1016/j.biopsych.2018.03.008 | 0.368 | |||
| 2018 | McLean CK, Narayan S, Lin SY, Rai N, Chung Y, Hipolito MS, Cascella NG, Nurnberger JI, Ishizuka K, Sawa AS, Nwulia EA. Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder. Translational Psychiatry. 8: 81. PMID 29666369 DOI: 10.1038/S41398-018-0126-6 | 0.508 | |||
| 2018 | Akamine S, Sagata N, Sakai Y, Kato TA, Nakahara T, Matsushita Y, Togao O, Hiwatashi A, Sanefuji M, Ishizaki Y, Torisu H, Saitsu H, Matsumoto N, Hara T, Sawa A, et al. Early-onset epileptic encephalopathy and severe developmental delay in an association with de novo double mutations inand. Epilepsia Open. 3: 81-85. PMID 29588991 DOI: 10.1002/epi4.12085 | 0.676 | |||
| 2018 | Wong DF, Kuwabara H, Horti AG, Roberts JM, Nandi A, Casella N, Brasic J, Weerts EM, Kitzmiller K, Phan JA, Gapasin L, Sawa A, Valentine H, Wand G, George N, et al. PET Brain imaging of α7-nAChR with [18F]ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia. The International Journal of Neuropsychopharmacology. PMID 29522184 DOI: 10.1093/Ijnp/Pyy021 | 0.308 | |||
| 2018 | Srivastava R, Faust T, Ramos A, Ishizuka K, Sawa A. Dynamic Changes of the Mitochondria in Psychiatric Illnesses: New Mechanistic Insights From Human Neuronal Models. Biological Psychiatry. PMID 29486891 DOI: 10.1016/J.Biopsych.2018.01.007 | 0.807 | |||
| 2018 | Posporelis S, Coughlin JM, Marsman A, Pradhan S, Tanaka T, Wang H, Varvaris M, Ward R, Higgs C, Edwards JA, Ford CN, Kim PK, Lloyd AM, Edden RAE, Schretlen DJ, ... ... Sawa A, et al. Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 3: 248-254. PMID 29486866 DOI: 10.1016/J.Bpsc.2017.04.003 | 0.798 | |||
| 2018 | Ooms M, Tsujikawa T, Lohith TG, Mabins SN, Zoghbi SS, Sumitomo A, Jaaro-Peled H, Kimura Y, Telu S, Pike VW, Tomoda T, Innis RB, Sawa A, Fujita M. [C]( R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18758997. PMID 29430995 DOI: 10.1177/0271678X18758997 | 0.732 | |||
| 2018 | Fukudome D, Hayes LN, Faust TE, Foss CA, Kondo MA, Lee BJ, Saito A, Kano SI, Coughlin JM, Kamiya A, Pomper MG, Sawa A, Niwa M. Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances. Schizophrenia Research. PMID 29398205 DOI: 10.1016/J.Schres.2018.01.015 | 0.791 | |||
| 2018 | Coughlin J, Notter T, Du Y, Pomper M, Sawa A, Meyer U. 6.1 STUDY OF ALTERED NEUROIMMUNITY IN PSYCHOSIS USING PET-BASED IMAGING OF THE TRANSLOCATOR PROTEIN 18 KDA: PROMISES, PITFALLS, AND FUTURE DIRECTIONS Schizophrenia Bulletin. 44: S8-S8. DOI: 10.1093/Schbul/Sby014.018 | 0.597 | |||
| 2018 | Coughlin J, Du Y, Greene A, Horti A, Wong D, Sawa A, Pomper M. T246. Low Availability of the α7 Nicotinic Acetylcholine Receptor Distinguishes Recent Onset of Non-Affective Psychosis From Affective Psychosis: A Study Using [18F]ASEM PET Biological Psychiatry. 83: S224-S225. DOI: 10.1016/J.Biopsych.2018.02.583 | 0.585 | |||
| 2018 | Shevelkin A, Terrillion C, Crawford J, Kim S, Fukudome D, Sawa A, Kamiya A, Pletnikov M. T209. Selective DISC1 Knockdown in Astrocytes Produces Region-Dependent Effects on Cognitive Function Biological Psychiatry. 83: S209-S210. DOI: 10.1016/J.Biopsych.2018.02.546 | 0.497 | |||
| 2018 | Kulason S, Schretlen D, Sawa A, Ratnanather T, Ishizuka K. S228. Measuring the Relationship Between Specific Phosphorylation of DISC1 and Cortical Thickness in Psychotic Disorders Biological Psychiatry. 83: S436-S437. DOI: 10.1016/J.Biopsych.2018.02.1120 | 0.515 | |||
| 2017 | Gault JM, Davis R, Cascella NG, Saks ER, Corripio-Collado I, Anderson WS, Olincy A, Thompson JA, Pomarol-Clotet E, Sawa A, Daskalakis ZJ, Lipsman N, Abosch A. Approaches to neuromodulation for schizophrenia. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29242310 DOI: 10.1136/Jnnp-2017-316946 | 0.349 | |||
| 2017 | Park SJ, Lee SB, Suh Y, Kim SJ, Lee N, Hong JH, Park C, Woo Y, Ishizuka K, Kim JH, Berggren PO, Sawa A, Park SK. DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM. Cell Reports. 21: 2748-2759. PMID 29212023 DOI: 10.1016/J.Celrep.2017.11.043 | 0.714 | |||
| 2017 | Notter T, Coughlin JM, Sawa A, Meyer U. Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry. Molecular Psychiatry. 23: 36-47. PMID 29203847 DOI: 10.1038/Mp.2017.232 | 0.635 | |||
| 2017 | Sagata N, Kato TA, Kano SI, Ohgidani M, Shimokawa N, Sato-Kasai M, Hayakawa K, Kuwano N, Wilson AM, Ishizuka K, Kato S, Nakahara T, Nakahara-Kido M, Setoyama D, Sakai Y, ... ... Sawa A, et al. Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: a pilot study. Scientific Reports. 7: 13905. PMID 29066822 DOI: 10.1038/S41598-017-14440-7 | 0.793 | |||
| 2017 | Kamath V, Lasutschinkow P, Ishizuka K, Sawa A. Olfactory Functioning in First-Episode Psychosis. Schizophrenia Bulletin. PMID 28981913 DOI: 10.1093/Schbul/Sbx107 | 0.568 | |||
| 2017 | Shinohara R, Taniguchi M, Ehrlich AT, Yokogawa K, Deguchi Y, Cherasse Y, Lazarus M, Urade Y, Ogawa A, Kitaoka S, Sawa A, Narumiya S, Furuyashiki T. Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice. Molecular Psychiatry. 23: 1717-1730. PMID 28924188 DOI: 10.1038/Mp.2017.177 | 0.336 | |||
| 2017 | Nucifora LG, Tanaka T, Hayes LN, Kim M, Lee BJ, Matsuda T, Nucifora FC, Sedlak T, Mojtabai R, Eaton W, Sawa A. Reduction of plasma glutathione in psychosis associated with schizophrenia and bipolar disorder in translational psychiatry. Translational Psychiatry. 7: e1215. PMID 28892069 DOI: 10.1038/Tp.2017.178 | 0.621 | |||
| 2017 | Nucifora FC, Mihaljevic M, Lee BJ, Sawa A. Clozapine as a Model for Antipsychotic Development. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28653280 DOI: 10.1007/s13311-017-0552-9 | 0.361 | |||
| 2017 | Shao L, Lu B, Wen Z, Teng S, Wang L, Zhao Y, Wang L, Ishizuka K, Xu X, Sawa A, Song H, Ming G, Zhong Y. Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways. Human Molecular Genetics. PMID 28472294 DOI: 10.1093/Hmg/Ddx147 | 0.617 | |||
| 2017 | Segal-Gavish H, Gazit N, Barhum Y, Ben-Zur T, Taler M, Henry Hornfeld S, Gil-Ad I, Weizman A, Slutsky I, Niwa M, Kamiya A, Sawa A, Offen D, Barzilay R. BDNF Overexpression Prevents Cognitive Deficit Elicited by Adolescent Cannabis Exposure and Host Susceptibility Interaction. Human Molecular Genetics. PMID 28402427 DOI: 10.1093/Hmg/Ddx139 | 0.746 | |||
| 2017 | Lavoie J, Sawa A, Ishizuka K. Application of olfactory tissue and its neural progenitors to schizophrenia and psychiatric research. Current Opinion in Psychiatry. PMID 28333692 DOI: 10.1097/Yco.0000000000000327 | 0.734 | |||
| 2017 | Namkung H, Kim SH, Sawa A. The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology. Trends in Neurosciences. PMID 28314446 DOI: 10.1016/J.Tins.2017.02.002 | 0.676 | |||
| 2017 | Toritsuka M, Kimoto S, Muraki K, Kitagawa M, Kishimoto T, Sawa A, Tanigaki K. Regulation of striatal dopamine responsiveness by Notch/RBP-J signaling. Translational Psychiatry. 7: e1049. PMID 28267151 DOI: 10.1038/tp.2017.21 | 0.301 | |||
| 2017 | Tanaka M, Ishizuka K, Nekooki-Machida Y, Endo R, Takashima N, Sasaki H, Komi Y, Gathercole A, Huston E, Ishii K, Hui KK, Kurosawa M, Kim SH, Nukina N, Takimoto E, ... ... Sawa A, et al. Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease. The Journal of Clinical Investigation. PMID 28263187 DOI: 10.1172/Jci85594 | 0.56 | |||
| 2017 | Lavoie J, Gassó Astorga P, Segal-Gavish H, Wu YC, Chung Y, Cascella NG, Sawa A, Ishizuka K. The Olfactory Neural Epithelium As a Tool in Neuroscience. Trends in Molecular Medicine. PMID 28108112 DOI: 10.1016/J.Molmed.2016.12.010 | 0.772 | |||
| 2017 | Notter T, Coughlin JM, Gschwind T, Weber-Stadlbauer U, Wang Y, Kassiou M, Vernon AC, Benke D, Pomper MG, Sawa A, Meyer U. Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia. Molecular Psychiatry. PMID 28093569 DOI: 10.1038/Mp.2016.248 | 0.683 | |||
| 2017 | Sedlak T, Koga M, Shaffer L, Fahey J, Snyder S, Barker P, Sawa A. 175.2 A Glu That Binds Inflammation and Neurotransmission: Glutathione as a Glutamate Reservoir Schizophrenia Bulletin. 43: S89-S89. DOI: 10.1093/schbul/sbx021.239 | 0.472 | |||
| 2017 | Niwa M, Sawa A. 118.3 Glucocorticoid-Mediated Epigenetic Control of Dopaminergic Neurons in a Trajectory From Adolescent Stress to Adult Behavior Schizophrenia Bulletin. 43: S66-S66. DOI: 10.1093/Schbul/Sbx021.175 | 0.64 | |||
| 2017 | Notter T, Coughlin J, Gschwind T, Weber-Stadlbauer U, Wang Y, Kassiou M, Vernon A, Benke D, Pomper M, Sawa A, Meyer U. 117.2 Translational Evaluation of Translocator Protein (TSPO) as a Marker of Neuroinflammation in Schizophrenia Schizophrenia Bulletin. 43: S64-S64. DOI: 10.1093/Schbul/Sbx021.169 | 0.652 | |||
| 2017 | Tomoda T, Dzirasa K, Saudou F, Sawa A, Jaaro-Peled H. 439. Role for DISC1 in Sensorimotor Gating: Its Impact on Corticostriatal Transport of BDNF Biological Psychiatry. 81: S179-S180. DOI: 10.1016/J.Biopsych.2017.02.923 | 0.661 | |||
| 2017 | Ishizuka K, Tanaka M, Houslay M, Sawa A. 438. Amyloidogenic DISC1: Role for Psychiatric Manifestation in Neurodegenerative Disorders Biological Psychiatry. 81: S179. DOI: 10.1016/J.Biopsych.2017.02.922 | 0.531 | |||
| 2016 | Lee BJ, Marchionni L, Andrews CE, Norris AL, Nucifora LG, Wu YC, Wright RA, Pevsner J, Ross CA, Margolis RL, Sawa A, Nucifora FC. Analysis of differential gene expression mediated by clozapine in human postmortem brains. Schizophrenia Research. PMID 28038920 DOI: 10.1016/J.Schres.2016.12.017 | 0.535 | |||
| 2016 | Sumitomo A, Ueta K, Mauchi S, Hirai K, Horike K, Hikida T, Sakurai T, Sawa A, Tomoda T. Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits. Neuroscience Research. PMID 28017600 DOI: 10.1016/J.Neures.2016.12.004 | 0.545 | |||
| 2016 | Coughlin JM, Wang Y, Minn I, Bienko N, Ambinder EB, Xu X, Peters ME, Dougherty JW, Vranesic M, Koo SM, Ahn HH, Lee M, Cottrell C, Sair HI, Sawa A, et al. Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players. Jama Neurology. PMID 27893897 DOI: 10.1001/Jamaneurol.2016.3764 | 0.608 | |||
| 2016 | Coughlin JM, Hayes LN, Tanaka T, Xiao M, Yolken RH, Worley P, Leweke FM, Sawa A. Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features. Schizophrenia Research. PMID 27889384 DOI: 10.1016/J.Schres.2016.10.040 | 0.771 | |||
| 2016 | Gamo NJ, Birknow MR, Sullivan D, Kondo MA, Horiuchi Y, Sakurai T, Slusher BS, Sawa A. Valley of death: A proposal to build a "translational bridge" for the next generation. Neuroscience Research. PMID 27876581 DOI: 10.1016/J.Neures.2016.11.003 | 0.777 | |||
| 2016 | Nucifora LG, Wu YC, Lee BJ, Sha L, Margolis RL, Ross CA, Sawa A, Nucifora FC. A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation. Molecular Neuropsychiatry. 2: 133-144. PMID 27867938 DOI: 10.1159/000447358 | 0.463 | |||
| 2016 | Morita M, Wang Y, Sasaoka T, Okada K, Niwa M, Sawa A, Hikida T. Dopamine D2L Receptor Is Required for Visual Discrimination and Reversal Learning. Molecular Neuropsychiatry. 2: 124-132. PMID 27867937 DOI: 10.1159/000447970 | 0.683 | |||
| 2016 | Tanaka T, Matsuda T, Hayes LN, Yang S, Rodriguez K, Severance EG, Yolken RH, Sawa A, Eaton W. Infection and inflammation in schizophrenia and bipolar disorder. Neuroscience Research. PMID 27856235 DOI: 10.1016/j.neures.2016.11.002 | 0.586 | |||
| 2016 | Delevich K, Abi-Dargham A, Hall J, Sawa A. Studying schizophrenia in the post-genomic era: perspectives from the 2016 summer Banbury Workshop at Cold Spring Harbor Laboratory. Molecular Psychiatry. PMID 27777417 DOI: 10.1038/Mp.2016.197 | 0.371 | |||
| 2016 | Horiuchi Y, Kondo MA, Okada K, Takayanagi Y, Tanaka T, Ho T, Varvaris M, Tajinda K, Hiyama H, Ni K, Colantuoni C, Schretlen D, Cascella NG, Pevsner J, Ishizuka K, ... Sawa A, et al. Molecular signatures associated with cognitive deficits in schizophrenia: a study of biopsied olfactory neural epithelium. Translational Psychiatry. 6: e915. PMID 27727244 DOI: 10.1038/Tp.2016.154 | 0.592 | |||
| 2016 | Hayes LN, Shevelkin A, Zeledon M, Steel G, Chen PL, Obie C, Pulver A, Avramopoulos D, Valle D, Sawa A, Pletnikov MV. Neuregulin 3 Knockout Mice Exhibit Behaviors Consistent with Psychotic Disorders. Molecular Neuropsychiatry. 2: 79-87. PMID 27606322 DOI: 10.1159/000445836 | 0.824 | |||
| 2016 | Xia M, Broek JA, Jouroukhin Y, Schoenfelder J, Abazyan S, Jaaro-Peled H, Sawa A, Bahn S, Pletnikov M. Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study. Molecular Neuropsychiatry. 2: 28-36. PMID 27606318 DOI: 10.1159/000444587 | 0.726 | |||
| 2016 | Furukubo-Tokunaga K, Kurita K, Honjo K, Pandey H, Ando T, Takayama K, Arai Y, Mochizuki H, Ando M, Kamiya A, Sawa A. Visualization of DISC1-Dysbindin interaction in glutamatergic synaptic termini in fruit flies. Molecular Psychiatry. 21: 1157. PMID 27545194 DOI: 10.1038/Mp.2016.142 | 0.482 | |||
| 2016 | Tankou S, Ishii K, Elliott C, Yalla KC, Day JP, Furukori K, Kubo KI, Brandon NJ, Tang Q, Hayward G, Nakajima K, Houslay MD, Kamiya A, Baillie G, Ishizuka K, ... Sawa A, et al. SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex. Molecular Neuropsychiatry. 2: 20-27. PMID 27525255 DOI: 10.1159/000444257 | 0.806 | |||
| 2016 | Sawa A, Sedlak TW. Oxidative stress and inflammation in schizophrenia. Schizophrenia Research. PMID 27395767 DOI: 10.1016/j.schres.2016.06.014 | 0.346 | |||
| 2016 | Wang Y, Coughlin JM, Ma S, Endres CJ, Kassiou M, Sawa A, Dannals RF, Petri M, Pomper MG. Neuroimaging of translocator protein in patients with systemic lupus erythematosus: a pilot study using [11C]DPA-713 positron emission tomography. Lupus. PMID 27387599 DOI: 10.1177/0961203316657432 | 0.624 | |||
| 2016 | Saito A, Taniguchi Y, Kim SH, Selvakumar B, Perez G, Ballinger MD, Zhu X, Sabra J, Jallow M, Yan P, Ito K, Rajendran S, Hirotsune S, Wynshaw-Boris A, Snyder SH, ... Sawa A, et al. Developmental Alcohol Exposure Impairs Activity-Dependent S-Nitrosylation of NDEL1 for Neuronal Maturation. Cerebral Cortex (New York, N.Y. : 1991). PMID 27371763 DOI: 10.1093/Cercor/Bhw201 | 0.666 | |||
| 2016 | Jaaro-Peled H, Altimus C, LeGates T, Cash-Padgett T, Zoubovsky S, Hikida T, Ishizuka K, Hattar S, Mongrain V, Sawa A. Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1. Neuroscience Research. PMID 27354230 DOI: 10.1016/J.Neures.2016.06.006 | 0.776 | |||
| 2016 | Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Sawa A, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/J.Biopsych.2016.05.004 | 0.509 | |||
| 2016 | Macpherson T, Morita M, Wang Y, Sasaoka T, Sawa A, Hikida T. Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCage. Learning & Memory (Cold Spring Harbor, N.Y.). 23: 359-64. PMID 27317196 DOI: 10.1101/Lm.042507.116 | 0.518 | |||
| 2016 | Nucifora FC, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, et al. Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. Nature Communications. 7: 11792. PMID 27273569 DOI: 10.1038/Ncomms11792 | 0.566 | |||
| 2016 | Kim SH, Shahani N, Bae BI, Sbodio JI, Chung Y, Nakaso K, Paul BD, Sawa A. Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53. Human Molecular Genetics. PMID 27206983 DOI: 10.1093/Hmg/Ddw115 | 0.787 | |||
| 2016 | Coughlin JM, Wang Y, Ambinder EB, Ward RE, Minn I, Vranesic M, Kim PK, Ford CN, Higgs C, Hayes LN, Schretlen DJ, Dannals RF, Kassiou M, Sawa A, Pomper MG. In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [(11)C]DPA-713 PET and analysis of CSF and plasma. Translational Psychiatry. 6: e777. PMID 27070405 DOI: 10.1038/Tp.2016.40 | 0.743 | |||
| 2016 | Furukubo-Tokunaga K, Kurita K, Honjo K, Pandey H, Ando T, Takayama K, Arai Y, Mochizuki H, Ando M, Kamiya A, Sawa A. DISC1 causes associative memory and neurodevelopmental defects in fruit flies. Molecular Psychiatry. PMID 26976042 DOI: 10.1038/Mp.2016.15 | 0.545 | |||
| 2016 | Millan MJ, Andrieux A, Bartzokis G, Cadenhead K, Dazzan P, Fusar-Poli P, Gallinat J, Giedd J, Grayson DR, Heinrichs M, Kahn R, Krebs MO, Leboyer M, Lewis D, Marin O, ... ... Sawa A, et al. Altering the course of schizophrenia: progress and perspectives. Nature Reviews. Drug Discovery. PMID 26939910 DOI: 10.1038/Nrd.2016.28 | 0.393 | |||
| 2016 | Niwa M, Lee RS, Tanaka T, Okada K, Kano SI, Sawa A. A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons. Human Molecular Genetics. PMID 26908623 DOI: 10.1093/Hmg/Ddw019 | 0.798 | |||
| 2016 | Kondo MA, Fukudome D, Smith DR, Gallagher M, Kamiya A, Sawa A. Dimensional assessment of behavioral changes in the cuprizone short-term exposure model for psychosis. Neuroscience Research. PMID 26869217 DOI: 10.1016/J.Neures.2016.01.006 | 0.751 | |||
| 2016 | Sawa A, Ishizuka K, Katsanis N. The potential of DISC1 protein as a therapeutic target for mental illness. Expert Opinion On Therapeutic Targets. PMID 26810812 DOI: 10.1517/14728222.2016.1146694 | 0.503 | |||
| 2016 | Tomoda T, Sumitomo A, Jaaro-Peled H, Sawa A. Utility and validity of DISC1 mouse models in biological psychiatry. Neuroscience. PMID 26768401 DOI: 10.1016/J.Neuroscience.2015.12.061 | 0.745 | |||
| 2016 | Niwa M, Cash-Padgett T, Kubo KI, Saito A, Ishii K, Sumitomo A, Taniguchi Y, Ishizuka K, Jaaro-Peled H, Tomoda T, Nakajima K, Sawa A, Kamiya A. DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1 Molecular Psychiatry. DOI: 10.1038/Mp.2016.154 | 0.807 | |||
| 2015 | Seshadri S, Faust T, Ishizuka K, Delevich K, Chung Y, Kim SH, Cowles M, Niwa M, Jaaro-Peled H, Tomoda T, Lai C, Anton ES, Li B, Sawa A. Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex. Nature Communications. 6: 10118. PMID 26656849 DOI: 10.1038/Ncomms10118 | 0.811 | |||
| 2015 | Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... Sawa A, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/J.Stemcr.2015.10.011 | 0.318 | |||
| 2015 | Koga M, Serritella AV, Sawa A, Sedlak TW. Implications for reactive oxygen species in schizophrenia pathogenesis. Schizophrenia Research. PMID 26589391 DOI: 10.1016/j.schres.2015.06.022 | 0.394 | |||
| 2015 | Zeledón M, Eckart N, Taub M, Vernon H, Szymanksi M, Wang R, Chen PL, Nestadt G, McGrath JA, Sawa A, Pulver AE, Avramopoulos D, Valle D. Identification and functional studies of regulatory variants responsible for the association of NRG3 with a delusion phenotype in schizophrenia. Molecular Neuropsychiatry. 1: 36-46. PMID 26528484 DOI: 10.1159/000371518 | 0.8 | |||
| 2015 | Hayashi Y, Sawa A, Hikida T. Impaired hippocampal activity at the goal zone on the place preference task in a DISC1 mouse model. Neuroscience Research. PMID 26497623 DOI: 10.1016/J.Neures.2015.10.005 | 0.561 | |||
| 2015 | Cash-Padgett T, Sawa A, Jaaro-Peled H. Increased stereotypy in conditional Cxcr4 knockout mice. Neuroscience Research. PMID 26458529 DOI: 10.1016/J.Neures.2015.10.001 | 0.729 | |||
| 2015 | Ueda S, Niwa M, Hioki H, Sohn J, Kaneko T, Sawa A, Sakurai T. Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex. Molecular Neuropsychiatry. 1: 94-104. PMID 26457295 DOI: 10.1159/000430095 | 0.654 | |||
| 2015 | Passeri E, Jones-Brando L, Bordón C, Sengupta S, Wilson AM, Primerano A, Rapoport JL, Ishikuza K, Kano SI, Yolken RH, Sawa A. Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls. Microbes and Infection / Institut Pasteur. PMID 26432947 DOI: 10.1016/J.Micinf.2015.09.023 | 0.81 | |||
| 2015 | Altimus C, Harrold J, Jaaro-Peled H, Sawa A, Foster DJ. Disordered ripples are a common feature of genetically distinct mouse models relevant to schizophrenia. Molecular Neuropsychiatry. 1: 52-59. PMID 26417572 DOI: 10.1159/000380765 | 0.718 | |||
| 2015 | Sakurai T, Gamo NJ, Hikida T, Kim SH, Murai T, Tomoda T, Sawa A. Converging models of schizophrenia - Network alterations of prefrontal cortex underlying cognitive impairments. Progress in Neurobiology. PMID 26408506 DOI: 10.1016/J.Pneurobio.2015.09.010 | 0.808 | |||
| 2015 | Landek-Salgado MA, Faust TE, Sawa A. Molecular substrates of schizophrenia: homeostatic signaling to connectivity. Molecular Psychiatry. PMID 26390828 DOI: 10.1038/Mp.2015.141 | 0.653 | |||
| 2015 | Passeri E, Wilson AM, Primerano A, Kondo MA, Sengupta S, Srivastava R, Koga M, Obie C, Zandi PP, Goes FS, Valle D, Rapoport JL, Sawa A, Kano SI, Ishizuka K. Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities. Neuroscience Research. PMID 26260244 DOI: 10.1016/J.Neures.2015.07.011 | 0.79 | |||
| 2015 | Posporelis S, Paspali A, Takayanagi Y, Sawa A, Banerjea P, Kyriakopoulos M. Demographic and clinical correlates of suicidality in adolescents attending a specialist community mental health service: a naturalistic study. Journal of Mental Health (Abingdon, England). 1-5. PMID 26203534 DOI: 10.3109/09638237.2015.1022249 | 0.758 | |||
| 2015 | Rais R, Wozniak K, Wu Y, Niwa M, Stathis M, Alt J, Giroux M, Sawa A, Rojas C, Slusher BS. Selective CNS Uptake of the GCP-II Inhibitor 2-PMPA following Intranasal Administration. Plos One. 10: e0131861. PMID 26151906 DOI: 10.1371/Journal.Pone.0131861 | 0.64 | |||
| 2015 | Ballinger MD, Saito A, Abazyan B, Taniguchi Y, Huang CH, Ito K, Zhu X, Segal H, Jaaro-Peled H, Sawa A, Mackie K, Pletnikov MV, Kamiya A. Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory. Neurobiology of Disease. PMID 26093170 DOI: 10.1016/J.Nbd.2015.06.006 | 0.757 | |||
| 2015 | Nomura J, Jaaro-Peled H, Lewis E, Nuñez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, ... ... Sawa A, et al. Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice. Molecular Psychiatry. PMID 26008737 DOI: 10.1038/Mp.2015.61 | 0.788 | |||
| 2015 | Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, Shahani N, Itakura M, Ono Y, Azuma YT, Inui T, Kamiya A, Sawa A, Takeuchi T. Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. The Journal of Biological Chemistry. 290: 14493-503. PMID 25882840 DOI: 10.1074/Jbc.M114.635607 | 0.78 | |||
| 2015 | Barodia SK, Park SK, Ishizuka K, Sawa A, Kamiya A. Half-life of DISC1 protein and its pathological significance under hypoxia stress. Neuroscience Research. 97: 1-6. PMID 25738396 DOI: 10.1016/J.Neures.2015.02.008 | 0.667 | |||
| 2015 | Coughlin JM, Tanaka T, Marsman A, Wang H, Bonekamp S, Kim PK, Higgs C, Varvaris M, Edden RA, Pomper M, Schretlen D, Barker PB, Sawa A. Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia. Current Molecular Medicine. 15: 176-83. PMID 25732147 DOI: 10.2174/1566524015666150303104811 | 0.733 | |||
| 2015 | Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, ... ... Sawa A, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146 DOI: 10.2174/1566524015666150303110300 | 0.794 | |||
| 2015 | Zoubovsky S, Oh EC, Cash-Padgett T, Johnson AW, Hou Z, Mori S, Gallagher M, Katsanis N, Sawa A, Jaaro-Peled H. Neuroanatomical and behavioral deficits in mice haploinsufficient for Pericentriolar material 1 (Pcm1). Neuroscience Research. PMID 25697395 DOI: 10.1016/J.Neures.2015.02.002 | 0.718 | |||
| 2015 | Coughlin JM, Wang Y, Munro CA, Ma S, Yue C, Chen S, Airan R, Kim PK, Adams AV, Garcia C, Higgs C, Sair HI, Sawa A, Smith G, Lyketsos CG, et al. Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study. Neurobiology of Disease. 74: 58-65. PMID 25447235 DOI: 10.1016/J.Nbd.2014.10.019 | 0.634 | |||
| 2015 | Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A. Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade. The Journal of Biological Chemistry. 290: 56-64. PMID 25391652 DOI: 10.1074/Jbc.M114.596205 | 0.774 | |||
| 2015 | Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. DISC1 regulates trafficking and processing of APP and Aβ generation. Molecular Psychiatry. 20: 874-9. PMID 25224257 DOI: 10.1038/Mp.2014.100 | 0.8 | |||
| 2015 | Zhang M, Sasaki H, Saitoh T, Koitabashi N, Zhu G, Tsujimura T, Lee D, Tristan C, Shahani N, Kariya T, Tsuchiya Y, Jaaro-Peled H, Slusher B, Kass D, Taguchi K, ... ... Sawa A, et al. NUCLEAR GLYCELALDEHYDE-3-PHOSPHATE DEHYDROGENASE SIGNALING MEDIATES PATHOLOGICAL CARDIAC HYPERTROPHY VIA P300 AND MYOCYTE ENHANCER FACTOR 2 Journal of the American College of Cardiology. 65: A2153. DOI: 10.1016/S0735-1097(15)62153-2 | 0.779 | |||
| 2014 | Narayan S, McLean C, Sawa A, Lin SY, Rai N, Hipolito MS, Cascella N, Nurnberger JJ, Ishizuka K, Nwulia EA. Olfactory neurons obtained through nasal biopsy combined with laser-capture microdissection: a potential approach to study treatment response in mental disorders. Journal of Visualized Experiments : Jove. PMID 25549156 DOI: 10.3791/51853 | 0.562 | |||
| 2014 | Takayanagi Y, Petersen L, Laursen TM, Cascella NG, Sawa A, Mortensen PB, Eaton WW. Risk of schizophrenia spectrum and affective disorders associated with small for gestational age birth and height in adulthood. Schizophrenia Research. 160: 230-2. PMID 25458575 DOI: 10.1016/j.schres.2014.10.018 | 0.34 | |||
| 2014 | Lee RS, Sawa A. Environmental stressors and epigenetic control of the hypothalamic-pituitary-adrenal axis. Neuroendocrinology. 100: 278-87. PMID 25427939 DOI: 10.1159/000369585 | 0.336 | |||
| 2014 | Sawa A, Seidman LJ. Is prophylactic psychiatry around the corner? combating adolescent oxidative stress for adult psychosis and schizophrenia. Neuron. 83: 991-3. PMID 25189204 DOI: 10.1016/J.Neuron.2014.08.028 | 0.348 | |||
| 2014 | Ramos A, Rodríguez-Seoane C, Rosa I, Trossbach SV, Ortega-Alonso A, Tomppo L, Ekelund J, Veijola J, Järvelin MR, Alonso J, Veiga S, Sawa A, Hennah W, García A, Korth C, et al. Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1. Human Molecular Genetics. 23: 5859-65. PMID 24934694 DOI: 10.1093/Hmg/Ddu303 | 0.702 | |||
| 2014 | Gamo NJ, Sawa A. Human stem cells and surrogate tissues for basic and translational study of mental disorders. Biological Psychiatry. 75: 918-9. PMID 24862565 DOI: 10.1016/j.biopsych.2014.03.025 | 0.776 | |||
| 2014 | Hayes LN, Severance EG, Leek JT, Gressitt KL, Rohleder C, Coughlin JM, Leweke FM, Yolken RH, Sawa A. Inflammatory molecular signature associated with infectious agents in psychosis. Schizophrenia Bulletin. 40: 963-72. PMID 24743863 DOI: 10.1093/Schbul/Sbu052 | 0.718 | |||
| 2014 | Hayashi-Takagi A, Araki Y, Nakamura M, Vollrath B, Duron SG, Yan Z, Kasai H, Huganir RL, Campbell DA, Sawa A. PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence. Proceedings of the National Academy of Sciences of the United States of America. 111: 6461-6. PMID 24706880 DOI: 10.1073/Pnas.1321109111 | 0.733 | |||
| 2014 | Emiliani FE, Sedlak TW, Sawa A. Oxidative stress and schizophrenia: recent breakthroughs from an old story. Current Opinion in Psychiatry. 27: 185-90. PMID 24613987 DOI: 10.1097/YCO.0000000000000054 | 0.377 | |||
| 2014 | Coughlin JM, Wang Y, Ma S, Yue C, Kim PK, Adams AV, Roosa HV, Gage KL, Stathis M, Rais R, Rojas C, McGlothan JL, Watkins CC, Sacktor N, Guilarte TR, ... ... Sawa A, et al. Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV. Journal of Neurovirology. 20: 219-32. PMID 24567030 DOI: 10.1007/S13365-014-0239-5 | 0.775 | |||
| 2014 | Posporelis S, Sawa A, Smith GS, Stitzer ML, Lyketsos CG, Chisolm MS. Promoting careers in academic research to psychiatry residents. Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry. 38: 185-90. PMID 24497181 DOI: 10.1007/S40596-014-0037-7 | 0.749 | |||
| 2014 | Porteous DJ, Thomson PA, Millar JK, Evans KL, Hennah W, Soares DC, McCarthy S, McCombie WR, Clapcote SJ, Korth C, Brandon NJ, Sawa A, Kamiya A, Roder JC, Lawrie SM, et al. DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan. Molecular Psychiatry. 19: 141-3. PMID 24457522 DOI: 10.1038/Mp.2013.160 | 0.569 | |||
| 2014 | Watkins CC, Sawa A, Pomper MG. Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application. Translational Psychiatry. 4: e350. PMID 24448212 DOI: 10.1038/Tp.2013.119 | 0.785 | |||
| 2014 | Brennand KJ, Landek-Salgado MA, Sawa A. Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells. Biological Psychiatry. 75: 936-44. PMID 24331955 DOI: 10.1016/J.Biopsych.2013.10.025 | 0.36 | |||
| 2014 | Wei J, Graziane NM, Wang H, Zhong P, Wang Q, Liu W, Hayashi-Takagi A, Korth C, Sawa A, Brandon NJ, Yan Z. Regulation of N-methyl-D-aspartate receptors by disrupted-in-schizophrenia-1. Biological Psychiatry. 75: 414-24. PMID 23906531 DOI: 10.1016/J.Biopsych.2013.06.009 | 0.783 | |||
| 2014 | Suzuki M, Takayanagi M, Wentz J, Takayanagi Y, Schretlen D, Ceyhan E, Sawa A, Barta P, Ratnanather T, Cascella N. Poster #T228 REDUCED ANTERIOR CINGULATE GRAY MATTER VOLUME AND THICKNESS IN SUBJECTS WITH DEFICIT SCHIZOPHRENIA Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)71044-8 | 0.332 | |||
| 2014 | Nucifora F, Nucifora L, Arbez N, Roby E, Yu L, Wei D, DeLisi L, Sawa A, Ross C, Margolis R. Poster #T175 NPAS3: NEW GENETIC AND BIOLOGICAL FINDINGS WITH IMPLICATIONS FOR PROTEIN AGGREGATION AND SCHIZOPHRENIA Schizophrenia Research. 153: S351. DOI: 10.1016/S0920-9964(14)70991-0 | 0.513 | |||
| 2014 | Posporelis S, Varvaris M, Marsman A, Coughlin JM, Bonekamp S, Kim P, Edden R, Schretlen DJ, Cascella N, Barker PB, Sawa A. Poster #S49 AN INITIAL REPORT ON METABOLIC DEFECTS IN RECENT ONSET SCHIZOPHRENIA WITH A 7 TESLA MRI SCANNER: LINK TO CHANGES IN BRAIN TEMPERATURE AND COGNITION Schizophrenia Research. 153: S106. DOI: 10.1016/S0920-9964(14)70328-7 | 0.801 | |||
| 2014 | Sawa A, Horiuchi Y, Cascella N, Schretlen D, Ishizuka K. ELUCIDATING THE MOLECULAR PATHOPHYSIOLOGY OF MENTAL ILLNESS WITH OLFACTORY NEURONAL CELLS AND INDUCED PLURIPOTENT STEM CELLS Schizophrenia Research. 153: S45. DOI: 10.1016/S0920-9964(14)70146-X | 0.538 | |||
| 2014 | Sawa A, Niwa M, Lee R. ADOLESCENT STRESS-INDUCED EPIGENETIC CONTROL OF NEURONAL NETWORKS Schizophrenia Research. 153: S3. DOI: 10.1016/S0920-9964(14)70009-X | 0.637 | |||
| 2014 | Patil SA, Kano S, Sawa A, Maegawa GH. Using small molecules to increase the direct conversion of culture fibroblasts from MPS II patients into induced-neuronal (iN) cells Molecular Genetics and Metabolism. 111: S84-S85. DOI: 10.1016/J.Ymgme.2013.12.202 | 0.672 | |||
| 2013 | Takayanagi Y, Gerner G, Takayanagi M, Rao V, Vannorsdall TD, Sawa A, Schretlen DJ, Cascella NG. Hippocampal volume reduction correlates with apathy in traumatic brain injury, but not schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences. 25: 292-301. PMID 24247856 DOI: 10.1176/Appi.Neuropsych.12040093 | 0.327 | |||
| 2013 | Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders. Neuroscience Research. 77: 247-50. PMID 24120685 DOI: 10.1016/J.Neures.2013.09.010 | 0.749 | |||
| 2013 | Toritsuka M, Kimoto S, Muraki K, Landek-Salgado MA, Yoshida A, Yamamoto N, Horiuchi Y, Hiyama H, Tajinda K, Keni N, Illingworth E, Iwamoto T, Kishimoto T, Sawa A, Tanigaki K. Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model. Proceedings of the National Academy of Sciences of the United States of America. 110: 17552-7. PMID 24101523 DOI: 10.1073/Pnas.1312661110 | 0.416 | |||
| 2013 | Takayanagi M, Wentz J, Takayanagi Y, Schretlen DJ, Ceyhan E, Wang L, Suzuki M, Sawa A, Barta PE, Ratnanather JT, Cascella NG. Reduced anterior cingulate gray matter volume and thickness in subjects with deficit schizophrenia. Schizophrenia Research. 150: 484-90. PMID 24035178 DOI: 10.1016/J.Schres.2013.07.036 | 0.349 | |||
| 2013 | Takayanagi Y, Cascella NG, Santora D, Gregory PE, Sawa A, Eaton WW. Relationships between serum leptin level and severity of positive symptoms in schizophrenia. Neuroscience Research. 77: 97-101. PMID 23896201 DOI: 10.1016/j.neures.2013.07.003 | 0.322 | |||
| 2013 | Tezuka T, Tamura M, Kondo MA, Sakaue M, Okada K, Takemoto K, Fukunari A, Miwa K, Ohzeki H, Kano S, Yasumatsu H, Sawa A, Kajii Y. Cuprizone short-term exposure: astrocytic IL-6 activation and behavioral changes relevant to psychosis. Neurobiology of Disease. 59: 63-8. PMID 23867234 DOI: 10.1016/j.nbd.2013.07.003 | 0.792 | |||
| 2013 | Johnson AW, Jaaro-Peled H, Shahani N, Sedlak TW, Zoubovsky S, Burruss D, Emiliani F, Sawa A, Gallagher M. Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness. Proceedings of the National Academy of Sciences of the United States of America. 110: 12462-7. PMID 23840059 DOI: 10.1073/Pnas.1307925110 | 0.811 | |||
| 2013 | Kannan G, Sawa A, Pletnikov MV. Mouse models of gene-environment interactions in schizophrenia. Neurobiology of Disease. 57: 5-11. PMID 23748077 DOI: 10.1016/j.nbd.2013.05.012 | 0.414 | |||
| 2013 | Soda T, Frank C, Ishizuka K, Baccarella A, Park YU, Flood Z, Park SK, Sawa A, Tsai LH. DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. Molecular Psychiatry. 18: 898-908. PMID 23587879 DOI: 10.1038/mp.2013.38 | 0.548 | |||
| 2013 | Kondo MA, Tajinda K, Colantuoni C, Hiyama H, Seshadri S, Huang B, Pou S, Furukori K, Hookway C, Jaaro-Peled H, Kano SI, Matsuoka N, Harada K, Ni K, Pevsner J, ... Sawa A, et al. Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control. Translational Psychiatry. 3: e243. PMID 23549417 DOI: 10.1038/Tp.2013.19 | 0.807 | |||
| 2013 | Mor E, Kano S, Colantuoni C, Sawa A, Navon R, Shomron N. MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients. Neurobiology of Disease. 55: 1-10. PMID 23542694 DOI: 10.1016/J.Nbd.2013.03.011 | 0.733 | |||
| 2013 | Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano S, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, et al. Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia. 61: 679-93. PMID 23382131 DOI: 10.1002/Glia.22461 | 0.708 | |||
| 2013 | Sakurai T, Shinobu LA, Sawa A. Schizophrenia research in 2013: are we making progress? Neurobiology of Disease. 53: 1-2. PMID 23380149 DOI: 10.1016/J.Nbd.2013.01.021 | 0.361 | |||
| 2013 | Seshadri S, Zeledon M, Sawa A. Synapse-specific contributions in the cortical pathology of schizophrenia. Neurobiology of Disease. 53: 26-35. PMID 23336981 DOI: 10.1016/J.Nbd.2013.01.009 | 0.809 | |||
| 2013 | Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, Kano S, Ozaki N, Nabeshima T, Sawa A. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science (New York, N.Y.). 339: 335-9. PMID 23329051 DOI: 10.1126/Science.1226931 | 0.8 | |||
| 2013 | Jaaro-Peled H, Niwa M, Foss CA, Murai R, de Los Reyes S, Kamiya A, Mateo Y, O'Donnell P, Cascella NG, Nabeshima T, Guilarte TR, Pomper MG, Sawa A. Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging. Human Molecular Genetics. 22: 1574-80. PMID 23314019 DOI: 10.1093/Hmg/Ddt007 | 0.796 | |||
| 2013 | Narayan S, Nakajima K, Sawa A. DISC1: a key lead in studying cortical development and associated brain disorders. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 19: 451-64. PMID 23300216 DOI: 10.1177/1073858412470168 | 0.391 | |||
| 2013 | Kano S, Colantuoni C, Han F, Zhou Z, Yuan Q, Wilson A, Takayanagi Y, Lee Y, Rapoport J, Eaton W, Cascella N, Ji H, Goldman D, Sawa A. Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia. Molecular Psychiatry. 18: 740-2. PMID 22925834 DOI: 10.1038/Mp.2012.120 | 0.796 | |||
| 2013 | Ma TM, Abazyan S, Abazyan B, Nomura J, Yang C, Seshadri S, Sawa A, Snyder SH, Pletnikov MV. Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion. Molecular Psychiatry. 18: 557-67. PMID 22801410 DOI: 10.1038/mp.2012.97 | 0.725 | |||
| 2013 | Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A. Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Molecular Psychiatry. 18: 10-1. PMID 22349781 DOI: 10.1038/Mp.2012.6 | 0.823 | |||
| 2012 | Hikida T, Gamo NJ, Sawa A. DISC1 as a therapeutic target for mental illnesses. Expert Opinion On Therapeutic Targets. 16: 1151-60. PMID 23130881 DOI: 10.1517/14728222.2012.719879 | 0.823 | |||
| 2012 | Rais R, Thomas AG, Wozniak K, Wu Y, Jaaro-Peled H, Sawa A, Strick CA, Engle SJ, Brandon NJ, Rojas C, Slusher BS, Tsukamoto T. Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 2067-73. PMID 22837388 DOI: 10.1124/Dmd.112.046482 | 0.676 | |||
| 2012 | Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, GarcÃa Ã, Requena JR, Hipolito M, Rai N, et al. Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Human Molecular Genetics. 21: 4406-18. PMID 22798627 DOI: 10.1093/Hmg/Dds273 | 0.826 | |||
| 2012 | Golzio C, Willer J, Talkowski ME, Oh EC, Taniguchi Y, Jacquemont S, Reymond A, Sun M, Sawa A, Gusella JF, Kamiya A, Beckmann JS, Katsanis N. KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant. Nature. 485: 363-7. PMID 22596160 DOI: 10.1038/Nature11091 | 0.553 | |||
| 2012 | Yang X, Ewald ER, Huo Y, Tamashiro KL, Salvatori R, Sawa A, Wand GS, Lee RS. Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5. Biochemical and Biophysical Research Communications. 420: 570-5. PMID 22445894 DOI: 10.1016/J.Bbrc.2012.03.035 | 0.312 | |||
| 2012 | Lin CY, Sawa A, Jaaro-Peled H. Better understanding of mechanisms of schizophrenia and bipolar disorder: from human gene expression profiles to mouse models. Neurobiology of Disease. 45: 48-56. PMID 21914480 DOI: 10.1016/J.Nbd.2011.08.025 | 0.821 | |||
| 2012 | Shahani N, Sawa A. Protein S-nitrosylation: role for nitric oxide signaling in neuronal death. Biochimica Et Biophysica Acta. 1820: 736-42. PMID 21803124 DOI: 10.1016/J.Bbagen.2011.07.010 | 0.7 | |||
| 2012 | Mouri A, Koseki T, Narusawa S, Niwa M, Mamiya T, Kano S, Sawa A, Nabeshima T. Mouse strain differences in phencyclidine-induced behavioural changes. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 767-79. PMID 21733237 DOI: 10.1017/S146114571100085X | 0.788 | |||
| 2012 | Taniguchi Y, Young-Pearse T, Sawa A, Kamiya A. In utero electroporation as a tool for genetic manipulation in vivo to study psychiatric disorders: from genes to circuits and behaviors. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 18: 169-79. PMID 21551077 DOI: 10.1177/1073858411399925 | 0.574 | |||
| 2012 | Cardarelli RA, Sawa A, O'Donnell P. Poster #80 DISRUPTION OF PREFRONTAL FAST-SPIKING INTERNEURONS IN THE DISC1-DN MOUSE MODEL OF SCHIZOPHRENIA Schizophrenia Research. 136: S120. DOI: 10.1016/S0920-9964(12)70395-X | 0.558 | |||
| 2012 | Abazvan B, Ma TM, Nomura J, Abazyan S, Sawa A, Snyder SH, Pletnikov MV. Poster #5 DISC1 AND SERINE RACEMASE INTERACT IN ASTROCYTES TO REGULATE D-SERINE PRODUCTION Schizophrenia Research. 136. DOI: 10.1016/S0920-9964(12)70321-3 | 0.47 | |||
| 2012 | Pletnikov MV, Ma TM, Nomura J, Abazyan B, Abazyan S, Sawa A, Snyder SH. DISC1 INTERACTS WITH SERINE RACEMASE TO MODULATE D-SERINE PRODUCTION IN ASTROCYTES Schizophrenia Research. 136: S62. DOI: 10.1016/S0920-9964(12)70234-7 | 0.463 | |||
| 2012 | Sawa A. OXIDATIVE STRESS AND INFLAMMATION IN THE PATHOLOGY OF SCHIZOPHRENIA: DATA FROM PATIENT NEURON BIOLOGY AND BRAIN IMAGING Schizophrenia Research. 136: S44-S45. DOI: 10.1016/S0920-9964(12)70160-3 | 0.384 | |||
| 2011 | Kondo M, Sawa A. Anti-/Propsychotic drug signaling via heteromeric GPCRs--a balancing act? Cell. 147: 964-5. PMID 22118451 DOI: 10.1016/j.cell.2011.11.012 | 0.704 | |||
| 2011 | Brandon NJ, Sawa A. Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nature Reviews. Neuroscience. 12: 707-22. PMID 22095064 DOI: 10.1038/nrn3120 | 0.34 | |||
| 2011 | Mitchell KJ, Huang ZJ, Moghaddam B, Sawa A. Following the genes: a framework for animal modeling of psychiatric disorders. Bmc Biology. 9: 76. PMID 22078115 DOI: 10.1186/1741-7007-9-76 | 0.314 | |||
| 2011 | Porteous DJ, Millar JK, Brandon NJ, Sawa A. DISC1 at 10: connecting psychiatric genetics and neuroscience. Trends in Molecular Medicine. 17: 699-706. PMID 22015021 DOI: 10.1016/j.molmed.2011.09.002 | 0.359 | |||
| 2011 | Cascella NG, Gerner GJ, Fieldstone SC, Sawa A, Schretlen DJ. The insula-claustrum region and delusions in schizophrenia. Schizophrenia Research. 133: 77-81. PMID 21875780 DOI: 10.1016/J.Schres.2011.08.004 | 0.351 | |||
| 2011 | Nagai T, Kitahara Y, Ibi D, Nabeshima T, Sawa A, Yamada K. Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment. Behavioural Brain Research. 225: 305-10. PMID 21835207 DOI: 10.1016/j.bbr.2011.07.049 | 0.395 | |||
| 2011 | Kano S, Nwulia E, Niwa M, Chen Y, Sawa A, Cascella N. Altered MHC class I expression in dorsolateral prefrontal cortex of nonsmoker patients with schizophrenia. Neuroscience Research. 71: 289-93. PMID 21801761 DOI: 10.1016/J.Neures.2011.07.1818 | 0.794 | |||
| 2011 | Flores R, Hirota Y, Armstrong B, Sawa A, Tomoda T. DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathway. Neuroscience Research. 71: 71-7. PMID 21664390 DOI: 10.1016/j.neures.2011.05.014 | 0.374 | |||
| 2011 | Hayashi-Takagi A, Barker PB, Sawa A. Readdressing synaptic pruning theory for schizophrenia: Combination of brain imaging and cell biology. Communicative & Integrative Biology. 4: 211-2. PMID 21655443 DOI: 10.4161/cib.4.2.14492 | 0.739 | |||
| 2011 | Koga M, Serritella AV, Messmer MM, Hayashi-Takagi A, Hester LD, Snyder SH, Sawa A, Sedlak TW. Glutathione is a physiologic reservoir of neuronal glutamate. Biochemical and Biophysical Research Communications. 409: 596-602. PMID 21539809 DOI: 10.1016/j.bbrc.2011.04.087 | 0.744 | |||
| 2011 | Zoubovsky SP, Pogorelov VM, Taniguchi Y, Kim SH, Yoon P, Nwulia E, Sawa A, Pletnikov MV, Kamiya A. Working memory deficits in neuronal nitric oxide synthase knockout mice: potential impairments in prefrontal cortex mediated cognitive function. Biochemical and Biophysical Research Communications. 408: 707-12. PMID 21539806 DOI: 10.1016/J.Bbrc.2011.04.097 | 0.612 | |||
| 2011 | Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, ... ... Sawa A, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473: 92-6. PMID 21471969 DOI: 10.1038/Nature09859 | 0.797 | |||
| 2011 | Ramsey AJ, Milenkovic M, Oliveira AF, Escobedo-Lozoya Y, Seshadri S, Salahpour A, Sawa A, Yasuda R, Caron MG. Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 5795-800. PMID 21436042 DOI: 10.1073/Pnas.1012621108 | 0.473 | |||
| 2011 | Ozeki Y, Pickard BS, Kano S, Malloy MP, Zeledon M, Sun DQ, Fujii K, Wakui K, Shirayama Y, Fukushima Y, Kunugi H, Hashimoto K, Muir WJ, Blackwood DH, Sawa A. A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression. Neuroscience Research. 69: 154-60. PMID 20955740 DOI: 10.1016/J.Neures.2010.10.003 | 0.803 | |||
| 2011 | Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, Crozier RA, Revilla-Sanchez R, Kelly MP, Dunlop AJ, Murdoch H, Taylor N, Xie Y, Pausch M, Hayashi-Takagi A, Ishizuka K, ... ... Sawa A, et al. The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Molecular Psychiatry. 16: 1006-23. PMID 20838393 DOI: 10.1038/Mp.2010.87 | 0.791 | |||
| 2011 | Shahani N, Sawa A. Nitric oxide signaling and nitrosative stress in neurons: role for S-nitrosylation. Antioxidants & Redox Signaling. 14: 1493-504. PMID 20812870 DOI: 10.1089/Ars.2010.3580 | 0.701 | |||
| 2011 | Tristan C, Shahani N, Sedlak TW, Sawa A. The diverse functions of GAPDH: views from different subcellular compartments. Cellular Signalling. 23: 317-23. PMID 20727968 DOI: 10.1016/J.Cellsig.2010.08.003 | 0.795 | |||
| 2011 | Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV. Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. Molecular Psychiatry. 16: 293-306. PMID 20048751 DOI: 10.1038/Mp.2009.144 | 0.569 | |||
| 2011 | Niwa M, Sawa A. How the brain senses environmental factors and is affected? Neuroscience Research. 71: e13. DOI: 10.1016/J.Neures.2011.07.049 | 0.635 | |||
| 2011 | Ayhan Y, Jaaro-Peled H, Sawa A, Pletnikov MV. DISC1 mouse models Neuromethods. 59: 211-229. DOI: 10.1007/978-1-61779-157-4_9 | 0.645 | |||
| 2010 | Abazyan B, Nomura J, Kannan G, Ishizuka K, Tamashiro KL, Nucifora F, Pogorelov V, Ladenheim B, Yang C, Krasnova IN, Cadet JL, Pardo C, Mori S, Kamiya A, Vogel MW, ... Sawa A, et al. Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. Biological Psychiatry. 68: 1172-81. PMID 21130225 DOI: 10.1016/J.Biopsych.2010.09.022 | 0.742 | |||
| 2010 | Young-Pearse TL, Suth S, Luth ES, Sawa A, Selkoe DJ. Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10431-40. PMID 20685985 DOI: 10.1523/Jneurosci.1445-10.2010 | 0.441 | |||
| 2010 | Lipina TV, Niwa M, Jaaro-Peled H, Fletcher PJ, Seeman P, Sawa A, Roder JC. Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia. Genes, Brain, and Behavior. 9: 777-89. PMID 20618446 DOI: 10.1111/J.1601-183X.2010.00615.X | 0.809 | |||
| 2010 | Hayashi MA, Guerreiro JR, Charych E, Kamiya A, Barbosa RL, Machado MF, Campeiro JD, Oliveira V, Sawa A, Camargo AC, Brandon NJ. Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth. Molecular and Cellular Neurosciences. 44: 353-61. PMID 20462516 DOI: 10.1016/J.Mcn.2010.04.006 | 0.56 | |||
| 2010 | Cascella NG, Fieldstone SC, Rao VA, Pearlson GD, Sawa A, Schretlen DJ. Gray-matter abnormalities in deficit schizophrenia. Schizophrenia Research. 120: 63-70. PMID 20452187 DOI: 10.1016/J.Schres.2010.03.039 | 0.379 | |||
| 2010 | Hayashi-Takagi A, Sawa A. Disturbed synaptic connectivity in schizophrenia: convergence of genetic risk factors during neurodevelopment. Brain Research Bulletin. 83: 140-6. PMID 20433911 DOI: 10.1016/j.brainresbull.2010.04.007 | 0.73 | |||
| 2010 | Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/Pnas.0909284107 | 0.821 | |||
| 2010 | Niwa M, Kamiya A, Murai R, Kubo K, Gruber AJ, Tomita K, Lu L, Tomisato S, Jaaro-Peled H, Seshadri S, Hiyama H, Huang B, Kohda K, Noda Y, O'Donnell P, ... ... Sawa A, et al. Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron. 65: 480-9. PMID 20188653 DOI: 10.1016/J.Neuron.2010.01.019 | 0.818 | |||
| 2010 | Tajinda K, Ishizuka K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Neuronal biomarkers from patients with mental illnesses: a novel method through nasal biopsy combined with laser-captured microdissection. Molecular Psychiatry. 15: 231-2. PMID 20168323 DOI: 10.1038/Mp.2009.73 | 0.504 | |||
| 2010 | Schretlen DJ, Vannorsdall TD, Winicki JM, Mushtaq Y, Hikida T, Sawa A, Yolken RH, Dickerson FB, Cascella NG. Neuroanatomic and cognitive abnormalities related to herpes simplex virus type 1 in schizophrenia. Schizophrenia Research. 118: 224-31. PMID 20153952 DOI: 10.1016/J.Schres.2010.01.008 | 0.577 | |||
| 2010 | Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, Dunlop AJ, Makino Y, Seshadri AJ, Ishizuka K, Srivastava DP, Xie Z, Baraban JM, Houslay MD, Tomoda T, Brandon NJ, ... ... Sawa A, et al. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nature Neuroscience. 13: 327-32. PMID 20139976 DOI: 10.1038/Nn.2487 | 0.82 | |||
| 2010 | Ou XM, Stockmeier CA, Meltzer HY, Overholser JC, Jurjus GJ, Dieter L, Chen K, Lu D, Johnson C, Youdim MB, Austin MC, Luo J, Sawa A, May W, Shih JC. A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. Biological Psychiatry. 67: 855-63. PMID 20022592 DOI: 10.1016/J.Biopsych.2009.10.032 | 0.311 | |||
| 2010 | Jaaro-Peled H, Ayhan Y, Pletnikov MV, Sawa A. Review of pathological hallmarks of schizophrenia: comparison of genetic models with patients and nongenetic models. Schizophrenia Bulletin. 36: 301-13. PMID 19903746 DOI: 10.1093/Schbul/Sbp133 | 0.745 | |||
| 2010 | Ishizuka K, Tajinda K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Negative symptoms of schizophrenia correlate with impairment on the University of Pennsylvania smell identification test. Neuroscience Research. 66: 106-10. PMID 19819272 DOI: 10.1016/J.Neures.2009.10.001 | 0.534 | |||
| 2010 | Ibi D, Nagai T, Koike H, Kitahara Y, Mizoguchi H, Niwa M, Jaaro-Peled H, Nitta A, Yoneda Y, Nabeshima T, Sawa A, Yamada K. Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood. Behavioural Brain Research. 206: 32-7. PMID 19716847 DOI: 10.1016/J.Bbr.2009.08.027 | 0.805 | |||
| 2010 | Moghaddam B, Gaisler-Salomon I, O′Donnell P, Sawa A, Sokoloff P, Uhlhaas P. MAKING CONNECTIONS: ABNORMAL WHITE MATTER DEVELOPMENT IN THE EARLY STAGES OF SCHIZOPHRENIA Schizophrenia Research. 117: 110. DOI: 10.1016/J.Schres.2010.02.026 | 0.336 | |||
| 2010 | Ishizuka K, Kano S, Colantuoni C, Schretlen D, Cascella NG, Sawa A. A translational approach for schizophrenia: Systematic cell/tissue engineering combined with detailed phenotypic characterization and molecular brain imaging Neuroscience Research. 68: e18. DOI: 10.1016/J.Neures.2010.07.315 | 0.762 | |||
| 2010 | Horiuchi Y, Ishii S, Kano S, Ishizuka K, Okada Y, Colantuoni C, Valle D, Cascella NG, Akamatsu W, Sawa A, Okano H. Generation of induced pluripotent stem cells from patients with schizophrenia Neuroscience Research. 68: e314. DOI: 10.1016/J.Neures.2010.07.1395 | 0.755 | |||
| 2010 | Shahani N, Young-Pearse T, Selkoe D, Sawa A. P2-247: Role of Disrupted-in-Schizophrenia-1 (DISC1) in amyloid precursor protein (APP) processing and Aβ generation Alzheimer's & Dementia. 6: S386-S387. DOI: 10.1016/J.Jalz.2010.05.1296 | 0.697 | |||
| 2009 | Sawa A. Genetic animal models for schizophrenia: advantages and limitations of genetic manipulation in drosophila, zebrafish, rodents, and primates. Progress in Brain Research. 179: 3-6. PMID 20302812 DOI: 10.1016/S0079-6123(09)17901-3 | 0.383 | |||
| 2009 | Sawa A. Preface. This volume focuses on how genetic models for schizophrenia, that is, manipulation in genetic susceptibility factors for the disease, have potential in opening a new window of better understanding of etiology-relevant mechanisms. Progress in Brain Research. 179: vii. PMID 19932335 DOI: 10.1016/S0079-6123(09)17919-0 | 0.349 | |||
| 2009 | Nakajima H, Amano W, Kubo T, Fukuhara A, Ihara H, Azuma YT, Tajima H, Inui T, Sawa A, Takeuchi T. Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death. The Journal of Biological Chemistry. 284: 34331-41. PMID 19837666 DOI: 10.1074/jbc.M109.027698 | 0.305 | |||
| 2009 | Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A. Understanding the role of DISC1 in psychiatric disease and during normal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12768-75. PMID 19828788 DOI: 10.1523/Jneurosci.3355-09.2009 | 0.379 | |||
| 2009 | Jaaro-Peled H, Hayashi-Takagi A, Seshadri S, Kamiya A, Brandon NJ, Sawa A. Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. Trends in Neurosciences. 32: 485-95. PMID 19712980 DOI: 10.1016/J.Tins.2009.05.007 | 0.822 | |||
| 2009 | Sawa A. Cortical development and glutamatergic dysregulation in schizophrenia. Biological Psychiatry. 66: 530-2. PMID 19712774 DOI: 10.1016/j.biopsych.2009.07.016 | 0.403 | |||
| 2009 | Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Aggrawal N, Hester L, Doré S, Snyder SH, Sawa A. GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation. Neuron. 63: 81-91. PMID 19607794 DOI: 10.1016/J.Neuron.2009.05.024 | 0.739 | |||
| 2009 | Ayhan Y, Sawa A, Ross CA, Pletnikov MV. Animal models of gene-environment interactions in schizophrenia. Behavioural Brain Research. 204: 274-81. PMID 19379776 DOI: 10.1016/J.Bbr.2009.04.010 | 0.53 | |||
| 2009 | Cascella NG, Schretlen DJ, Sawa A. Schizophrenia and epilepsy: is there a shared susceptibility? Neuroscience Research. 63: 227-35. PMID 19367784 DOI: 10.1016/J.Neures.2009.01.002 | 0.388 | |||
| 2009 | Sawa A, Cascella NG. Peripheral olfactory system for clinical and basic psychiatry: a promising entry point to the mystery of brain mechanism and biomarker identification in schizophrenia. The American Journal of Psychiatry. 166: 137-9. PMID 19188289 DOI: 10.1176/appi.ajp.2008.08111702 | 0.363 | |||
| 2009 | Pletnikov M, Ayhan Y, Abazyan B, Pardo C, Sawa A, Vogel M, Ross C. S.16.04 DISC1 mouse model of gene-environment interactions in schizophrenia European Neuropsychopharmacology. 19. DOI: 10.1016/S0924-977X(09)70256-1 | 0.521 | |||
| 2009 | Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Hester L, Doré S, Snyder SH, Sawa A. GOSPEL: A Neuroprotective Protein that Binds to GAPDH upon S-Nitrosylation (DOI:10.1016/j.neuron.2009.05.024) Neuron. 63: 709. DOI: 10.1016/J.Neuron.2009.08.032 | 0.754 | |||
| 2009 | Niwa M, Kamiya A, Murai R, Kubo K, Jaaro-Peled H, Lu L, Ozaki N, Nakajima K, Noda Y, Sawa A, Nabeshima T. Disturbance of Disrupted-in-Schizophrenia-1 during neurodevelopment develops phenotypes of psychiatric disorders related to dysfunction of the dopaminergic system Neuroscience Research. 65: S63. DOI: 10.1016/J.Neures.2009.09.189 | 0.812 | |||
| 2008 | Sawamura N, Ando T, Maruyama Y, Fujimuro M, Mochizuki H, Honjo K, Shimoda M, Toda H, Sawamura-Yamamoto T, Makuch LA, Hayashi A, Ishizuka K, Cascella NG, Kamiya A, Ishida N, ... ... Sawa A, et al. Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. Molecular Psychiatry. 13: 1138-48, 1069. PMID 18762802 DOI: 10.1038/Mp.2008.101 | 0.68 | |||
| 2008 | Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, Tsukita S, Pulver AE, Nakajima K, Cascella NG, Katsanis N, Sawa A. Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Archives of General Psychiatry. 65: 996-1006. PMID 18762586 DOI: 10.1001/Archpsyc.65.9.996 | 0.673 | |||
| 2008 | Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nature Cell Biology. 10: 866-73. PMID 18552833 DOI: 10.1038/Ncb1747 | 0.782 | |||
| 2008 | Burdick KE, Kamiya A, Hodgkinson CA, Lencz T, DeRosse P, Ishizuka K, Elashvili S, Arai H, Goldman D, Sawa A, Malhotra AK. Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Human Molecular Genetics. 17: 2462-73. PMID 18469341 DOI: 10.1093/Hmg/Ddn146 | 0.659 | |||
| 2008 | Kamiya A, Kitabatake Y, Sawa A. [Neurodevelopmental disturbance in the pathogenesis of major mental disorders]. Brain and Nerve = Shinkei Kenkyå« No Shinpo. 60: 445-52. PMID 18421986 | 0.561 | |||
| 2008 | Liu Z, Wang X, Yu Y, Li X, Wang T, Jiang H, Ren Q, Jiao Y, Sawa A, Moran T, Ross CA, Montell C, Smith WW. A Drosophila model for LRRK2-linked parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 105: 2693-8. PMID 18258746 DOI: 10.1073/Pnas.0708452105 | 0.482 | |||
| 2008 | Yasumoto F, Hayashi A, Kamiya A, Negishi T, Yoshikawa Y, Sawa A. Genetic manipulation of brain cultures from the primates: a novel tool for molecular studies of neuropsychiatric disorders. Molecular Psychiatry. 13: 116-8. PMID 18202692 DOI: 10.1038/Sj.Mp.4002113 | 0.543 | |||
| 2008 | Hikida T, Mustafa AK, Maeda K, Fujii K, Barrow RK, Saleh M, Huganir RL, Snyder SH, Hashimoto K, Sawa A. Modulation of D-serine levels in brains of mice lacking PICK1. Biological Psychiatry. 63: 997-1000. PMID 18191108 DOI: 10.1016/J.Biopsych.2007.09.025 | 0.794 | |||
| 2008 | Wang Q, Jaaro-Peled H, Sawa A, Brandon NJ. How has DISC1 enabled drug discovery? Molecular and Cellular Neurosciences. 37: 187-95. PMID 18055216 DOI: 10.1016/J.Mcn.2007.10.006 | 0.734 | |||
| 2007 | Oie S, Suenaga S, Sawa A, Kamiya A. Association between isolation sites of methicillin-resistant Staphylococcus aureus (MRSA) in patients with MRSA-positive body sites and MRSA contamination in their surrounding environmental surfaces. Japanese Journal of Infectious Diseases. 60: 367-9. PMID 18032836 | 0.407 | |||
| 2007 | Hashimoto R, Tankou S, Takeda M, Sawa A. Postsynaptic density: a key convergent site for schizophrenia susceptibility factors and possible target for drug development. Drugs of Today (Barcelona, Spain : 1998). 43: 645-54. PMID 17940640 DOI: 10.1358/dot.2007.43.9.1088821 | 0.79 | |||
| 2007 | Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, ... ... Sawa A, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/Sj.Mp.4002024 | 0.775 | |||
| 2007 | Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, Wu D, Xue R, Andradé M, Tankou S, Mori S, Gallagher M, Ishizuka K, Pletnikov M, Kida S, ... Sawa A, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proceedings of the National Academy of Sciences of the United States of America. 104: 14501-6. PMID 17675407 DOI: 10.1073/Pnas.0704774104 | 0.816 | |||
| 2007 | Hashimoto K, Sawa A, Iyo M. Increased levels of glutamate in brains from patients with mood disorders. Biological Psychiatry. 62: 1310-6. PMID 17574216 DOI: 10.1016/j.biopsych.2007.03.017 | 0.313 | |||
| 2007 | Cascella NG, Takaki M, Lin S, Sawa A. Neurodevelopmental involvement in schizophrenia: the olfactory epithelium as an alternative model for research. Journal of Neurochemistry. 102: 587-94. PMID 17488280 DOI: 10.1111/j.1471-4159.2007.4628.x | 0.409 | |||
| 2007 | Pletnikov MV, Xu Y, Ovanesov MV, Kamiya A, Sawa A, Ross CA. PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation. Neuroscience Research. 58: 234-44. PMID 17418909 DOI: 10.1016/J.Neures.2007.03.003 | 0.665 | |||
| 2007 | Maruyama Y, Ando T, Honjo K, Shimoda M, Mochizuki H, Toda H, Kamiya A, Ishida N, Tomoda T, Sawa A, Furukubo-Tokunaga K. Overexpression of DISC1 impairs associative learning and arousal in Drosophila Neuroscience Research. 58: S123. DOI: 10.1016/J.Neures.2007.06.1287 | 0.488 | |||
| 2007 | Hikida T, Jaaro-Peled H, Tankou S, Morita M, Pletnikov M, Kida S, Mori S, Sawa A. Production and analyses of mutant DISC1 transgenic mice: An animal model of schizophrenia Neuroscience Research. 58: S20. DOI: 10.1016/J.Neures.2007.06.117 | 0.801 | |||
| 2006 | Sawamura N, Sawa A. Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses. Annals of the New York Academy of Sciences. 1086: 126-33. PMID 17185511 DOI: 10.1196/annals.1377.018 | 0.435 | |||
| 2006 | Kamiya A, Tomoda T, Chang J, Takaki M, Zhan C, Morita M, Cascio MB, Elashvili S, Koizumi H, Takanezawa Y, Dickerson F, Yolken R, Arai H, Sawa A. DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Human Molecular Genetics. 15: 3313-23. PMID 17035248 DOI: 10.1093/Hmg/Ddl407 | 0.592 | |||
| 2006 | Bord L, Wheeler J, Paek M, Saleh M, Lyons-Warren A, Ross CA, Sawamura N, Sawa A. Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history. Neuroscience Research. 56: 286-93. PMID 16965828 DOI: 10.1016/J.Neures.2006.07.010 | 0.55 | |||
| 2006 | Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, Mori T, Nemoto K, Adachi N, Izumi A, Chiba S, Noguchi H, Suzuki T, Iwata N, Ozaki N, ... ... Sawa A, et al. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Human Molecular Genetics. 15: 3024-33. PMID 16959794 DOI: 10.1093/Hmg/Ddl244 | 0.599 | |||
| 2006 | Maeda K, Nwulia E, Chang J, Balkissoon R, Ishizuka K, Chen H, Zandi P, McInnis MG, Sawa A. Differential expression of disrupted-in-schizophrenia (DISC1) in bipolar disorder. Biological Psychiatry. 60: 929-35. PMID 16814263 DOI: 10.1016/J.Biopsych.2006.03.032 | 0.578 | |||
| 2006 | Ishizuka K, Paek M, Kamiya A, Sawa A. A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions. Biological Psychiatry. 59: 1189-97. PMID 16797264 DOI: 10.1016/J.Biopsych.2006.03.065 | 0.719 | |||
| 2006 | Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC. DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. The Journal of Comparative Neurology. 497: 436-50. PMID 16736468 DOI: 10.1002/Cne.21007 | 0.51 | |||
| 2006 | Hara MR, Cascio MB, Sawa A. GAPDH as a sensor of NO stress. Biochimica Et Biophysica Acta. 1762: 502-9. PMID 16574384 DOI: 10.1016/j.bbadis.2006.01.012 | 0.6 | |||
| 2006 | Lipska BK, Peters T, Hyde TM, Halim N, Horowitz C, Mitkus S, Weickert CS, Matsumoto M, Sawa A, Straub RE, Vakkalanka R, Herman MM, Weinberger DR, Kleinman JE. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Human Molecular Genetics. 15: 1245-58. PMID 16510495 DOI: 10.1093/Hmg/Ddl040 | 0.621 | |||
| 2006 | Hara MR, Thomas B, Cascio MB, Bae BI, Hester LD, Dawson VL, Dawson TM, Sawa A, Snyder SH. Neuroprotection by pharmacologic blockade of the GAPDH death cascade. Proceedings of the National Academy of Sciences of the United States of America. 103: 3887-9. PMID 16505364 DOI: 10.1073/Pnas.0511321103 | 0.788 | |||
| 2006 | Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, Ross CA, Ha HC, Li XJ, Snyder SH, Sawa A. Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proceedings of the National Academy of Sciences of the United States of America. 103: 3405-9. PMID 16492755 DOI: 10.1073/Pnas.0511316103 | 0.777 | |||
| 2006 | Hurt KJ, Sezen SF, Champion HC, Crone JK, Palese MA, Huang PL, Sawa A, Luo X, Musicki B, Snyder SH, Burnett AL. Alternatively spliced neuronal nitric oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America. 103: 3440-3. PMID 16488973 DOI: 10.1073/Pnas.0511326103 | 0.7 | |||
| 2006 | Fujii K, Maeda K, Hikida T, Mustafa AK, Balkissoon R, Xia J, Yamada T, Ozeki Y, Kawahara R, Okawa M, Huganir RL, Ujike H, Snyder SH, Sawa A. Serine racemase binds to PICK1: potential relevance to schizophrenia. Molecular Psychiatry. 11: 150-7. PMID 16314870 DOI: 10.1038/Sj.Mp.4001776 | 0.798 | |||
| 2006 | Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM. Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin. Neurobiology of Disease. 21: 381-91. PMID 16150600 DOI: 10.1016/J.Nbd.2005.07.014 | 0.519 | |||
| 2006 | Lyons-Warren A, Chang JJ, Balkissoon R, Kamiya A, Garant M, Nurnberger J, Scheftner W, Reich T, McMahon FJ, Kelsoe J, Gershon E, Coryell W, Byerley W, Berrettini W, DePaulo R, ... ... Sawa A, et al. Erratum: Evidence of association between bipolar disorder and Citron on chromosome 12q24 Molecular Psychiatry. 11: 612-612. DOI: 10.1038/Sj.Mp.4001842 | 0.506 | |||
| 2005 | Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, Sawamura N, Park U, Kudo C, Okawa M, Ross CA, Hatten ME, Nakajima K, Sawa A. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nature Cell Biology. 7: 1167-78. PMID 16299498 DOI: 10.1038/Ncb1328 | 0.731 | |||
| 2005 | Sawa A, Snyder SH. Genetics. Two genes link two distinct psychoses. Science (New York, N.Y.). 310: 1128-9. PMID 16293746 DOI: 10.1126/science.1121114 | 0.568 | |||
| 2005 | Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Human Molecular Genetics. 14: 3801-11. PMID 16239241 DOI: 10.1093/Hmg/Ddi396 | 0.561 | |||
| 2005 | Zhang X, Tochigi M, Ohashi J, Maeda K, Kato T, Okazaki Y, Kato N, Tokunaga K, Sawa A, Sasaki T. Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population. Schizophrenia Research. 79: 175-80. PMID 16039834 DOI: 10.1016/j.schres.2005.05.023 | 0.354 | |||
| 2005 | Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A. p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron. 47: 29-41. PMID 15996546 DOI: 10.1016/J.Neuron.2005.06.005 | 0.781 | |||
| 2005 | Lyons-Warren A, Chang JJ, Balkissoon R, Kamiya A, Garant M, Nurnberger J, Scheftner W, Reich T, McMahon F, Kelsoe J, Gershon E, Coryell W, Byerley W, Berrettini W, Depaulo R, ... ... Sawa A, et al. Evidence of association between bipolar disorder and Citron on chromosome 12q24. Molecular Psychiatry. 10: 807-9. PMID 15983625 DOI: 10.1038/Sj.Mp.4001703 | 0.496 | |||
| 2005 | Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature Cell Biology. 7: 665-74. PMID 15951807 DOI: 10.1038/Ncb1268 | 0.776 | |||
| 2005 | Sachs NA, Sawa A, Holmes SE, Ross CA, DeLisi LE, Margolis RL. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Molecular Psychiatry. 10: 758-64. PMID 15940305 DOI: 10.1038/Sj.Mp.4001667 | 0.544 | |||
| 2005 | Sawa A, Nagata E, Sutcliffe S, Dulloor P, Cascio MB, Ozeki Y, Roy S, Ross CA, Snyder SH. Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblasts. Neurobiology of Disease. 20: 267-74. PMID 15890517 DOI: 10.1016/J.Nbd.2005.02.013 | 0.674 | |||
| 2005 | Sawamura N, Sawamura-Yamamoto T, Ozeki Y, Ross CA, Sawa A. A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proceedings of the National Academy of Sciences of the United States of America. 102: 1187-92. PMID 15657124 DOI: 10.1073/Pnas.0406543102 | 0.633 | |||
| 2005 | Sawa A, Sawamura N, Balkissoon R. Disrupted-In-Schizophrenia-1 (DISC1): A promising lead in molecular analyzes of schizophrenia Clinical Neuroscience Research. 5: 23-30. DOI: 10.1016/j.cnr.2005.07.003 | 0.404 | |||
| 2004 | Oie S, Ishitobi J, Sawa A, Tomita M, Kamiya A. In vitro bactericidal activity of antimicrobial agents against enterohaemorrhagic Escherichia coli. The Journal of Antimicrobial Chemotherapy. 54: 897-903. PMID 15472004 DOI: 10.1093/jac/dkh442 | 0.397 | |||
| 2004 | Nagata E, Sawa A, Ross CA, Snyder SH. Autophagosome-like vacuole formation in Huntington's disease lymphoblasts. Neuroreport. 15: 1325-8. PMID 15167559 DOI: 10.1097/01.Wnr.0000127073.66692.8F | 0.619 | |||
| 2004 | Sawa A, Pletnikov MV, Kamiya A. Neuron-glia interactions clarify genetic-environmental links in mental illness. Trends in Neurosciences. 27: 294-7. PMID 15165731 DOI: 10.1016/J.Tins.2004.03.012 | 0.607 | |||
| 2004 | Ozeki Y, Okawa M, Sawa A. [DISC1 and schizophrenia]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 24: 87-91. PMID 15164617 | 0.502 | |||
| 2004 | Tsutsumi T, Holmes SE, McInnis MG, Sawa A, Callahan C, DePaulo JR, Ross CA, DeLisi LE, Margolis RL. Novel CAG/CTG repeat expansion mutations do not contribute to the genetic risk for most cases of bipolar disorder or schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 15-9. PMID 14681907 DOI: 10.1002/Ajmg.B.20058 | 0.539 | |||
| 2004 | Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A. Erratum: Disrupted-in-Schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth (Proceedings of the National Academy of Sciences of the United States of America (January 7, 2003) 100, 1 (289-294)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0405527101 | 0.749 | |||
| 2003 | Oie S, Uematsu T, Sawa A, Mizuno H, Tomita M, Ishida S, Okano Y, Kamiya A. In vitro effects of combinations of antipseudomonal agents against seven strains of multidrug-resistant Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. 52: 911-4. PMID 14585851 DOI: 10.1093/jac/dkg478 | 0.402 | |||
| 2003 | Sawa A, Tomoda T, Bae BI. Mechanisms of neuronal cell death in Huntington's disease. Cytogenetic and Genome Research. 100: 287-95. PMID 14526190 DOI: 10.1159/000072864 | 0.718 | |||
| 2003 | Sawa A, Kamiya A. Elucidating the pathogenesis of schizophrenia. Bmj (Clinical Research Ed.). 327: 632-3. PMID 14500408 DOI: 10.1136/Bmj.327.7416.632 | 0.602 | |||
| 2003 | Blackshaw S, Eliasson MJ, Sawa A, Watkins CC, Krug D, Gupta A, Arai T, Ferrante RJ, Snyder SH. Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity. Neuroscience. 119: 979-90. PMID 12831857 DOI: 10.1016/S0306-4522(03)00217-3 | 0.78 | |||
| 2003 | Sawa A, Snyder SH. Schizophrenia: neural mechanisms for novel therapies. Molecular Medicine (Cambridge, Mass.). 9: 3-9. PMID 12765334 DOI: 10.1007/Bf03402101 | 0.543 | |||
| 2003 | Igarashi S, Morita H, Bennett KM, Tanaka Y, Engelender S, Peters MF, Cooper JK, Wood JD, Sawa A, Ross CA. Inducible PC12 cell model of Huntington's disease shows toxicity and decreased histone acetylation. Neuroreport. 14: 565-8. PMID 12657886 DOI: 10.1097/00001756-200303240-00007 | 0.494 | |||
| 2003 | Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A. Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 100: 289-94. PMID 12506198 DOI: 10.1073/Pnas.0136913100 | 0.779 | |||
| 2003 | Nucifora FC, Ellerby LM, Wellington CL, Wood JD, Herring WJ, Sawa A, Hayden MR, Dawson VL, Dawson TM, Ross CA. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity. The Journal of Biological Chemistry. 278: 13047-55. PMID 12464607 DOI: 10.1074/Jbc.M211224200 | 0.586 | |||
| 2003 | Kirkpatrick B, Cascella N, Ozeki Y, Roberts R, Sawa A. DISC1-immunoreactive cells in the human brain Schizophrenia Research. 60: 72. DOI: 10.1016/S0920-9964(03)80599-6 | 0.484 | |||
| 2002 | Sawa A, Snyder SH. Schizophrenia: diverse approaches to a complex disease. Science (New York, N.Y.). 296: 692-5. PMID 11976442 DOI: 10.1126/science.1070532 | 0.589 | |||
| 2001 | Sawa A. Alteration of gene expression in Down's syndrome (DS) brains: its significance in neurodegeneration. Journal of Neural Transmission. Supplementum. 361-71. PMID 11771759 DOI: 10.1007/978-3-7091-6262-0_30 | 0.337 | |||
| 2001 | Luo HR, Saiardi A, Nagata E, Ye K, Yu H, Jung TS, Luo X, Jain S, Sawa A, Snyder SH. GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase. Neuron. 31: 439-51. PMID 11516400 DOI: 10.1016/S0896-6273(01)00384-1 | 0.491 | |||
| 2001 | Sawa A. Mechanisms for neuronal cell death and dysfunction in Huntington's disease: pathological cross-talk between the nucleus and the mitochondria? Journal of Molecular Medicine (Berlin, Germany). 79: 375-81. PMID 11466559 DOI: 10.1007/S001090100223 | 0.34 | |||
| 2001 | Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, L Dawson V, Dawson TM, Ross CA. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Human Molecular Genetics. 10: 919-26. PMID 11309365 DOI: 10.1093/Hmg/10.9.919 | 0.575 | |||
| 2001 | Saiardi A, Nagata E, Luo HR, Sawa A, Luo X, Snowman AM, Snyder SH. Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate. Proceedings of the National Academy of Sciences of the United States of America. 98: 2306-11. PMID 11226235 DOI: 10.1073/pnas.041614598 | 0.457 | |||
| 2000 | Takahashi M, Doré S, Ferris CD, Tomita T, Sawa A, Wolosker H, Borchelt DR, Iwatsubo T, Kim SH, Thinakaran G, Sisodia SS, Snyder SH. Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. Neuron. 28: 461-73. PMID 11144356 DOI: 10.1016/S0896-6273(00)00125-2 | 0.767 | |||
| 2000 | Fang M, Jaffrey SR, Sawa A, Ye K, Luo X, Snyder SH. Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron. 28: 183-93. PMID 11086993 DOI: 10.1016/S0896-6273(00)00095-7 | 0.661 | |||
| 2000 | Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy The Journal of Clinical Investigation. 106: 803. PMID 10995791 DOI: 10.1172/jci8273c1 | 0.769 | |||
| 2000 | Doré S, Goto S, Sampei K, Blackshaw S, Hester LD, Ingi T, Sawa A, Traystman RJ, Koehler RC, Snyder SH. Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia. Neuroscience. 99: 587-92. PMID 10974422 DOI: 10.1016/S0306-4522(00)00216-5 | 0.65 | |||
| 2000 | Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy. The Journal of Clinical Investigation. 106: 373-84. PMID 10930440 DOI: 10.1172/Jci8273 | 0.771 | |||
| 2000 | Blackshaw S, Sawa A, Sharp AH, Ross CA, Snyder SH, Khan AA. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1375-9. PMID 10877830 DOI: 10.1096/Fj.14.10.1375 | 0.674 | |||
| 2000 | Blackshaw S, Sawa A, Sharp AH, Ross CA, Snyder SH, Khan AA. Type 3 inositol 1,4,5‐trisphosphate receptor modulates cell death The Faseb Journal. 14: 1375-1379. DOI: 10.1096/fasebj.14.10.1375 | 0.635 | |||
| 2000 | Watkins CC, Barrows RK, Sawa A, Snyder SH, Ferris CD. Loss of neuronal nitric oxide synthase (NNOS) in a model of diabetic gastropathy: Reversal by insulin therapy and PDE-V inhibitors Gastroenterology. 118: A669. DOI: 10.1016/S0016-5085(00)84811-8 | 0.767 | |||
| 1999 | Sawa A. Neuronal cell death in Down's syndrome. Journal of Neural Transmission. Supplementum. 57: 87-97. PMID 10666670 DOI: 10.1007/978-3-7091-6380-1_6 | 0.363 | |||
| 1999 | Ferris CD, Jaffrey SR, Sawa A, Takahashi M, Brady SD, Barrow RK, Tysoe SA, Wolosker H, Barañano DE, Doré S, Poss KD, Snyder SH. Haem oxygenase-1 prevents cell death by regulating cellular iron. Nature Cell Biology. 1: 152-7. PMID 10559901 DOI: 10.1038/11072 | 0.773 | |||
| 1999 | Oie S, Sawa A, Kamiya A, Mizuno H. In-vitro effects of a combination of antipseudomonal antibiotics against multi-drug resistant Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. 44: 689-91. PMID 10552987 | 0.396 | |||
| 1999 | Sawa A, Wiegand GW, Cooper J, Margolis RL, Sharp AH, Lawler JF, Greenamyre JT, Snyder SH, Ross CA. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nature Medicine. 5: 1194-8. PMID 10502825 DOI: 10.1038/13518 | 0.63 | |||
| 1997 | Sawa A, Khan AA, Hester LD, Snyder SH. Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death. Proceedings of the National Academy of Sciences of the United States of America. 94: 11669-74. PMID 9326668 DOI: 10.1073/PNAS.94.21.11669 | 0.523 | |||
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