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Kristina Lorenz - Publications

Affiliations: 
1999-2015 Pharmacology and Toxicology University of Würzburg, Würzburg, Bayern, Germany 
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rodríguez-Soacha DA, Steinmüller SAM, Işbilir A, Fender J, Deventer MH, Ramírez YA, Tutov A, Sotriffer C, Stove CP, Lorenz K, Lohse MJ, Hislop JN, Decker M. Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CBR) "Cis-On" Agonist. Acs Chemical Neuroscience. 13: 2410-2435. PMID 35881914 DOI: 10.1021/acschemneuro.2c00160  0.519
2022 Lee J, Olivieri C, Ong C, Masterson LR, Gomes S, Lee BS, Schaefer F, Lorenz K, Veglia G, Rosner MR. Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121867119. PMID 35696587 DOI: 10.1073/pnas.2121867119  0.417
2022 Lorenz K, Rosner MR. Harnessing RKIP to Combat Heart Disease and Cancer. Cancers. 14. PMID 35205615 DOI: 10.3390/cancers14040867  0.301
2020 Tomasovic A, Brand T, Schanbacher C, Kramer S, Hümmert MW, Godoy P, Schmidt-Heck W, Nordbeck P, Ludwig J, Homann S, Wiegering A, Shaykhutdinov T, Kratz C, Knüchel R, Müller-Hermelink HK, ... ... Lorenz K, et al. Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects. Nature Communications. 11: 1733. PMID 32265441 DOI: 10.1038/s41467-020-15505-4  0.31
2019 Maimari T, Krasel C, Bünemann M, Lorenz K. The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors. Biochemical and Biophysical Research Communications. PMID 31604529 DOI: 10.1016/J.Bbrc.2019.09.135  0.636
2019 Jochmann S, Elkenani M, Mohamed BA, Buchholz E, Lbik D, Binder L, Lorenz K, Shah AM, Hasenfuß G, Toischer K, Schnelle M. Assessing the role of extracellular signal-regulated kinases 1 and 2 in volume overload-induced cardiac remodelling. Esc Heart Failure. PMID 31322843 DOI: 10.1002/ehf2.12497  0.314
2017 Skinner JJ, Wang S, Lee J, Ong C, Sommese R, Sivaramakrishnan S, Koelmel W, Hirschbeck M, Schindelin H, Kisker C, Lorenz K, Sosnick TR, Rosner MR. Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proceedings of the National Academy of Sciences of the United States of America. PMID 29208709 DOI: 10.1073/Pnas.1711543114  0.373
2017 Lorenz K, Rosner MR, Brand T, Schmitt JP. RKIP - Lessons of a better way for β-adrenergic receptor activation in the heart. The Journal of Physiology. PMID 28444807 DOI: 10.1113/Jp274064  0.407
2016 Brietz A, Schuch KV, Wangorsch G, Lorenz K, Dandekar T. Analyzing ERK 1/2 signalling and targets. Molecular Biosystems. PMID 27301697 DOI: 10.1039/C6Mb00255B  0.327
2016 Nuber S, Zabel U, Lorenz K, Nuber A, Milligan G, Tobin AB, Lohse MJ, Hoffmann C. β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle. Nature. PMID 27007855 DOI: 10.1038/Nature17198  0.694
2016 McReynolds AC, Karra AS, Li Y, Lopez ED, Turjanski AG, Dioum E, Lorenz K, Zaganjor E, Stippec S, McGlynn K, Earnest S, Cobb MH. Phosphorylation or mutation of the ERK2 activation loop alters oligonucleotide binding. Biochemistry. PMID 26950759 DOI: 10.1021/Acs.Biochem.6B00096  0.325
2016 Schmid E, Neef S, Berlin C, Tomasovic A, Kahlert K, Nordbeck P, Deiss K, Denzinger S, Herrmann S, Wettwer E, Weidendorfer M, Becker D, Schäfer F, Wagner N, Ergün S, ... ... Lorenz K, et al. Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy. Nature Medicine. 22: 217. PMID 26845407 DOI: 10.1038/nm0216-217c  0.458
2015 Schmid E, Neef S, Berlin C, Tomasovic A, Kahlert K, Nordbeck P, Deiss K, Denzinger S, Herrmann S, Wettwer E, Weidendorfer M, Becker D, Schäfer F, Wagner N, Ergün S, ... ... Lorenz K, et al. Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy. Nature Medicine. PMID 26479924 DOI: 10.1038/Nm.3972  0.49
2015 Weise M, Vettel C, Spiger K, Gilsbach R, Hein L, Lorenz K, Wieland T, Aktories K, Orth JH. A systemic Pasteurella multocida toxin aggravates cardiac hypertrophy and fibrosis in mice. Cellular Microbiology. 17: 1320-31. PMID 25759205 DOI: 10.1111/Cmi.12436  0.409
2014 Lorenz K, Schmid E, Deiss K. RKIP: a governor of intracellular signaling. Critical Reviews in Oncogenesis. 19: 489-96. PMID 25597358  0.356
2014 Calebiro D, Hannawacker A, Lyga S, Bathon K, Zabel U, Ronchi C, Beuschlein F, Reincke M, Lorenz K, Allolio B, Kisker C, Fassnacht M, Lohse MJ. PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit. Nature Communications. 5: 5680. PMID 25477193 DOI: 10.1038/Ncomms6680  0.449
2014 Lorenz K, Stathopoulou K, Schmid E, Eder P, Cuello F. Heart failure-specific changes in protein kinase signalling. PflüGers Archiv : European Journal of Physiology. 466: 1151-62. PMID 24510065 DOI: 10.1007/s00424-014-1462-x  0.364
2014 Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl JM, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, et al. Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium. Cell. 156: 456-68. PMID 24485454 DOI: 10.1016/J.Cell.2014.01.006  0.353
2013 Ruppert C, Deiss K, Herrmann S, Vidal M, Oezkur M, Gorski A, Weidemann F, Lohse MJ, Lorenz K. Interference with ERK(Thr188) phosphorylation impairs pathological but not physiological cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: 7440-5. PMID 23589880 DOI: 10.1073/Pnas.1221999110  0.541
2012 Vidal M, Wieland T, Lohse MJ, Lorenz K. β-Adrenergic receptor stimulation causes cardiac hypertrophy via a Gβγ/Erk-dependent pathway. Cardiovascular Research. 96: 255-64. PMID 22843704 DOI: 10.1093/Cvr/Cvs249  0.628
2012 Deiss K, Kisker C, Lohse MJ, Lorenz K. Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2. The Journal of Biological Chemistry. 287: 23407-17. PMID 22610096 DOI: 10.1074/Jbc.M112.363812  0.563
2009 Reiner S, Ziegler N, Leon C, Lorenz K, von Hayn K, Gachet C, Lohse MJ, Hoffmann C. beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites. Molecular Pharmacology. 76: 1162-71. PMID 19741005 DOI: 10.1124/Mol.109.060467  0.709
2009 Lorenz K, Schmitt JP, Vidal M, Lohse MJ. Cardiac hypertrophy: targeting Raf/MEK/ERK1/2-signaling. The International Journal of Biochemistry & Cell Biology. 41: 2351-5. PMID 19666137 DOI: 10.1016/J.Biocel.2009.08.002  0.485
2009 Schmitt JP, Ahmad F, Lorenz K, Hein L, Schulz S, Asahi M, Maclennan DH, Seidman CE, Seidman JG, Lohse MJ. Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition. Circulation. 119: 436-44. PMID 19139388 DOI: 10.1161/Circulationaha.108.783506  0.458
2009 Lorenz K, Schmitt JP, Schmitteckert EM, Lohse MJ. A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy. Nature Medicine. 15: 75-83. PMID 19060905 DOI: 10.1038/Nm.1893  0.604
2008 Krasel C, Zabel U, Lorenz K, Reiner S, Al-Sabah S, Lohse MJ. Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization. The Journal of Biological Chemistry. 283: 31840-8. PMID 18801735 DOI: 10.1074/Jbc.M806086200  0.568
2008 Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nature Chemical Biology. 4: 126-31. PMID 18193048 DOI: 10.1038/Nchembio.64  0.714
2005 Buitrago M, Lorenz K, Maass AH, Oberdorf-Maass S, Keller U, Schmitteckert EM, Ivashchenko Y, Lohse MJ, Engelhardt S. The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy. Nature Medicine. 11: 837-44. PMID 16025126 DOI: 10.1038/Nm1272  0.582
2005 Krasel C, Bünemann M, Lorenz K, Lohse MJ. Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation. The Journal of Biological Chemistry. 280: 9528-35. PMID 15634674 DOI: 10.1074/Jbc.M413078200  0.702
2003 Lorenz K, Lohse MJ, Quitterer U. Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2. Nature. 426: 574-9. PMID 14654844 DOI: 10.1038/Nature02158  0.729
2003 Maack C, Böhm M, Vlaskin L, Dabew E, Lorenz K, Schäfers HJ, Lohse MJ, Engelhardt S. Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor. Circulation. 108: 348-53. PMID 12847069 DOI: 10.1161/01.Cir.0000080325.94345.8B  0.618
2003 Eichmann T, Lorenz K, Hoffmann M, Brockmann J, Krasel C, Lohse MJ, Quitterer U. The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site. The Journal of Biological Chemistry. 278: 8052-7. PMID 12486133 DOI: 10.1074/Jbc.M204795200  0.696
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