Richard W. Aldrich - Publications

Affiliations: 
Neurobiology University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Ion channels
Website:
http://clm.utexas.edu/AldrichLab/

143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Alexander SP, Mathie A, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Aldrich RW, Attali B, Baggetta AM, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels. British Journal of Pharmacology. 178: S157-S245. PMID 34529831 DOI: 10.1111/bph.15539  1
2021 Nathan S, Gabelli SB, Yoder JB, Srinivasan L, Aldrich RW, Tomaselli GF, Ben-Johny M, Amzel LM. Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation. The Journal of General Physiology. 153. PMID 33306788 DOI: 10.1085/jgp.202012722  0.01
2019 Liebeskind BJ, Aldrich RW, Marcotte EM. Ancestral reconstruction of protein interaction networks. Plos Computational Biology. 15: e1007396. PMID 31658251 DOI: 10.1371/Journal.Pcbi.1007396  1
2019 Edington SC, Halling DB, Bennett S, Middendorf T, Aldrich R, Baiz CR. Non-additive effects of binding site mutations in calmodulin. Biochemistry. PMID 31124357 DOI: 10.1021/Acs.Biochem.9B00096  1
2018 Scott LL, Iyer S, Philpo AE, Avalos MN, Wu NS, Shi T, Prakash BA, Nguyen TT, Mihic SJ, Aldrich RW, Pierce JT. A novel peptide restricts ethanol modulation of the BK channel and . The Journal of Pharmacology and Experimental Therapeutics. PMID 30158242 DOI: 10.1124/Jpet.118.251918  0.36
2018 Dockendorff C, Gandhi DM, Kimball IH, Eum KS, Rusinova R, Ingólfsson HI, Kapoor R, Peyear T, Dodge MW, Martin SF, Aldrich R, Andersen OS, Sack JT. Synthetic analogs of the snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT) reveal that lipid bilayer perturbation does not underlie its modulation of voltage-gated potassium channels. Biochemistry. PMID 29616558 DOI: 10.1021/Acs.Biochem.8B00292  1
2018 Edington SC, Gonzalez A, Middendorf TR, Halling DB, Aldrich RW, Baiz CR. Coordination to lanthanide ions distorts binding site conformation in calmodulin. Proceedings of the National Academy of Sciences of the United States of America. PMID 29545272 DOI: 10.1073/Pnas.1722042115  1
2018 Aldrich RW. Influences: Growing up in Yale Physiology. The Journal of General Physiology. PMID 29363565 DOI: 10.1085/jgp.201711990  0.01
2017 Kaczmarek LK, Aldrich RW, Chandy KG, Grissmer S, Wei AD, Wulff H. International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels. Pharmacological Reviews. 69: 1-11. PMID 28267675 DOI: 10.1124/Pr.116.012864  1
2017 Scott LL, Brecht EJ, Philpo A, Iyer S, Wu NS, Mihic SJ, Aldrich RW, Pierce J, Walton JP. A novel BK channel-targeted peptide suppresses sound evoked activity in the mouse inferior colliculus. Scientific Reports. 7: 42433. PMID 28195225 DOI: 10.1038/Srep42433  0.52
2016 Middendorf TR, Aldrich RW. Structural identifiability of equilibrium ligand-binding parameters. The Journal of General Physiology. PMID 27993952 DOI: 10.1085/jgp.201611702  1
2016 Middendorf TR, Aldrich RW. The structure of binding curves and practical identifiability of equilibrium ligand-binding parameters. The Journal of General Physiology. PMID 27993951 DOI: 10.1085/jgp.201611703  1
2016 Yan J, Li Q, Aldrich RW. Closed state-coupled C-type inactivation in BK channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298368 DOI: 10.1073/pnas.1607584113  1
2016 Halling DB, Liebeskind BJ, Hall AW, Aldrich RW. Conserved properties of individual Ca2+-binding sites in calmodulin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884197 DOI: 10.1073/pnas.1600385113  1
2015 Zhao R, Dai H, Mendelman N, Cuello LG, Chill JH, Goldstein SA. Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display. Proceedings of the National Academy of Sciences of the United States of America. PMID 26627718 DOI: 10.1073/Pnas.1514728112  1
2015 Aldrich RW. A new standard: A review of Handbook of Ion Channels. The Journal of General Physiology. 146: 119-21. PMID 26216856 DOI: 10.1085/jgp.201511461  0.01
2015 Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428  1
2015 Hines KE, Bankston JR, Aldrich RW. Analyzing single-molecule time series via nonparametric Bayesian inference. Biophysical Journal. 108: 540-56. PMID 25650922 DOI: 10.1016/J.Bpj.2014.12.016  1
2014 Hines KE, Middendorf TR, Aldrich RW. Determination of parameter identifiability in nonlinear biophysical models: A Bayesian approach. The Journal of General Physiology. 143: 401-16. PMID 24516188 DOI: 10.1085/jgp.201311116  1
2014 Halling DB, Kenrick SA, Riggs AF, Aldrich RW. Calcium-dependent stoichiometries of the KCa2.2 (SK) intracellular domain/calmodulin complex in solution. The Journal of General Physiology. 143: 231-52. PMID 24420768 DOI: 10.1085/Jgp.201311007  1
2014 Chen X, Yan J, Aldrich RW. BK channel opening involves side-chain reorientation of multiple deep-pore residues. Proceedings of the National Academy of Sciences of the United States of America. 111: E79-88. PMID 24367115 DOI: 10.1073/pnas.1321697111  1
2012 Yan J, Aldrich RW. BK potassium channel modulation by leucine-rich repeat-containing proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 7917-22. PMID 22547800 DOI: 10.1073/pnas.1205435109  1
2011 Glauser DA, Johnson BE, Aldrich RW, Goodman MB. Intragenic alternative splicing coordination is essential for Caenorhabditis elegans slo-1 gene function. Proceedings of the National Academy of Sciences of the United States of America. 108: 20790-5. PMID 22084100 DOI: 10.1073/Pnas.1116712108  1
2011 Johnson BE, Glauser DA, Dan-Glauser ES, Halling DB, Aldrich RW, Goodman MB. Alternatively spliced domains interact to regulate BK potassium channel gating. Proceedings of the National Academy of Sciences of the United States of America. 108: 20784-9. PMID 22049343 DOI: 10.1073/Pnas.1116795108  1
2011 Chen X, Aldrich RW. Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating. The Journal of General Physiology. 138: 137-54. PMID 21746846 DOI: 10.1085/jgp.201110632  1
2011 Li W, Aldrich RW. Electrostatic influences of charged inner pore residues on the conductance and gating of small conductance Ca2+ activated K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 108: 5946-53. PMID 21422289 DOI: 10.1073/Pnas.1103090108  1
2011 Liu H, Aldrich RW. Tissue-specific N terminus of the HCN4 channel affects channel activation. The Journal of Biological Chemistry. 286: 14209-14. PMID 21372143 DOI: 10.1074/jbc.M110.215640  1
2010 Yan J, Aldrich RW. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature. 466: 513-6. PMID 20613726 DOI: 10.1038/nature09162  1
2010 Girouard H, Bonev AD, Hannah RM, Meredith A, Aldrich RW, Nelson MT. Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction. Proceedings of the National Academy of Sciences of the United States of America. 107: 3811-6. PMID 20133576 DOI: 10.1073/Pnas.0914722107  1
2009 Li W, Halling DB, Hall AW, Aldrich RW. EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK-calmodulin interaction. The Journal of General Physiology. 134: 281-93. PMID 19752189 DOI: 10.1083/Jcb1866Oia14  1
2009 Li W, Aldrich RW. Activation of the SK potassium channel-calmodulin complex by nanomolar concentrations of terbium. Proceedings of the National Academy of Sciences of the United States of America. 106: 1075-80. PMID 19144926 DOI: 10.1073/Pnas.0812008106  1
2009 Fodor AA, Aldrich RW. Convergent evolution of alternative splices at domain boundaries of the BK channel. Annual Review of Physiology. 71: 19-36. PMID 18694345 DOI: 10.1146/annurev.physiol.010908.163124  1
2008 Imlach WL, Finch SC, Dunlop J, Meredith AL, Aldrich RW, Dalziel JE. The molecular mechanism of "ryegrass staggers," a neurological disorder of K+ channels. The Journal of Pharmacology and Experimental Therapeutics. 327: 657-64. PMID 18801945 DOI: 10.1124/jpet.108.143933  1
2008 Brown SM, Bentcheva-Petkova LM, Liu L, Hristov KL, Chen M, Kellett WF, Meredith AL, Aldrich RW, Nelson MT, Petkov GV. Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel. American Journal of Physiology. Renal Physiology. 295: F1149-57. PMID 18701628 DOI: 10.1152/Ajprenal.00440.2007  1
2008 Yan J, Olsen JV, Park KS, Li W, Bildl W, Schulte U, Aldrich RW, Fakler B, Trimmer JS. Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity. Molecular & Cellular Proteomics : McP. 7: 2188-98. PMID 18573811 DOI: 10.1074/Mcp.M800063-Mcp200  1
2008 Werner ME, Meredith AL, Aldrich RW, Nelson MT. Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R181-8. PMID 18480246 DOI: 10.1152/Ajpregu.00173.2008  1
2007 Pyott SJ, Meredith AL, Fodor AA, Vázquez AE, Yamoah EN, Aldrich RW. Cochlear function in mice lacking the BK channel alpha, beta1, or beta4 subunits. The Journal of Biological Chemistry. 282: 3312-24. PMID 17135251 DOI: 10.1074/Jbc.M608726200  1
2007 Werner ME, Knorn AM, Meredith AL, Aldrich RW, Nelson MT. Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R616-24. PMID 16931654 DOI: 10.1152/Ajpregu.00036.2006  1
2006 Filosa JA, Bonev AD, Straub SV, Meredith AL, Wilkerson MK, Aldrich RW, Nelson MT. Local potassium signaling couples neuronal activity to vasodilation in the brain. Nature Neuroscience. 9: 1397-1403. PMID 17013381 DOI: 10.1038/Nn1779  1
2006 Li W, Aldrich RW. State-dependent block of BK channels by synthesized shaker ball peptides. The Journal of General Physiology. 128: 423-41. PMID 16966472 DOI: 10.1085/Jgp.200609521  1
2006 Wilkens CM, Aldrich RW. State-independent block of BK channels by an intracellular quaternary ammonium. The Journal of General Physiology. 128: 347-64. PMID 16940557 DOI: 10.1085/jgp.200609579  1
2006 Meredith AL, Wiler SW, Miller BH, Takahashi JS, Fodor AA, Ruby NF, Aldrich RW. BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output. Nature Neuroscience. 9: 1041-9. PMID 16845385 DOI: 10.1038/nn1740  1
2006 Sack JT, Aldrich RW. Binding of a gating modifier toxin induces intersubunit cooperativity early in the Shaker K channel's activation pathway. The Journal of General Physiology. 128: 119-32. PMID 16801385 DOI: 10.1085/jgp.200609492  1
2006 Fodor AA, Aldrich RW. Statistical limits to the identification of ion channel domains by sequence similarity. The Journal of General Physiology. 127: 755-66. PMID 16735758 DOI: 10.1085/jgp.200509419  1
2006 Piskorowski RA, Aldrich RW. Relationship between pore occupancy and gating in BK potassium channels. The Journal of General Physiology. 127: 557-76. PMID 16636204 DOI: 10.1085/Jgp.200509482  1
2006 Misonou H, Menegola M, Buchwalder L, Park EW, Meredith A, Rhodes KJ, Aldrich RW, Trimmer JS. Immunolocalization of the Ca2+-activated K+ channel Slo1 in axons and nerve terminals of mammalian brain and cultured neurons. The Journal of Comparative Neurology. 496: 289-302. PMID 16566008 DOI: 10.1002/cne.20931  1
2005 Wei AD, Gutman GA, Aldrich R, Chandy KG, Grissmer S, Wulff H. International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels Pharmacological Reviews. 57: 463-472. PMID 16382103 DOI: 10.1124/Pr.57.4.9  1
2005 Brenner R, Chen QH, Vilaythong A, Toney GM, Noebels JL, Aldrich RW. BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nature Neuroscience. 8: 1752-9. PMID 16261134 DOI: 10.1038/Nn1573  1
2005 Werner ME, Zvara P, Meredith AL, Aldrich RW, Nelson MT. Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel. The Journal of Physiology. 567: 545-56. PMID 16020453 DOI: 10.1113/Jphysiol.2005.093823  1
2005 Thorneloe KS, Meredith AL, Knorn AM, Aldrich RW, Nelson MT. Urodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladder. American Journal of Physiology. Renal Physiology. 289: F604-10. PMID 15827347 DOI: 10.1152/Ajprenal.00060.2005  1
2004 Pyott SJ, Glowatzki E, Trimmer JS, Aldrich RW. Extrasynaptic localization of inactivating calcium-activated potassium channels in mouse inner hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9469-74. PMID 15509733 DOI: 10.1523/Jneurosci.3162-04.2004  1
2004 Fodor AA, Aldrich RW. Influence of conservation on calculations of amino acid covariance in multiple sequence alignments. Proteins. 56: 211-21. PMID 15211506 DOI: 10.1002/prot.20098  1
2004 Li W, Aldrich RW. Unique inner pore properties of BK channels revealed by quaternary ammonium block. The Journal of General Physiology. 124: 43-57. PMID 15197222 DOI: 10.1085/jgp.200409067  1
2004 Meredith AL, Thorneloe KS, Werner ME, Nelson MT, Aldrich RW. Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. The Journal of Biological Chemistry. 279: 36746-52. PMID 15184377 DOI: 10.1074/Jbc.M405621200  1
2004 Sack JT, Aldrich RW, Gilly WF. A gastropod toxin selectively slows early transitions in the Shaker K channel's activation pathway. The Journal of General Physiology. 123: 685-96. PMID 15148327 DOI: 10.1085/jgp.200409047  1
2004 Fodor AA, Aldrich RW. On evolutionary conservation of thermodynamic coupling in proteins. The Journal of Biological Chemistry. 279: 19046-50. PMID 15023994 DOI: 10.1074/jbc.M402560200  1
2004 Dekker JP, Fodor A, Aldrich RW, Yellen G. A perturbation-based method for calculating explicit likelihood of evolutionary co-variance in multiple sequence alignments. Bioinformatics (Oxford, England). 20: 1565-72. PMID 14962924 DOI: 10.1093/Bioinformatics/Bth128  1
2002 Piskorowski R, Aldrich RW. Calcium activation of BK(Ca) potassium channels lacking the calcium bowl and RCK domains. Nature. 420: 499-502. PMID 12466841 DOI: 10.1038/nature01199  1
2002 Horrigan FT, Aldrich RW. Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels. The Journal of General Physiology. 120: 267-305. PMID 12198087 DOI: 10.1085/jgp.20028605  1
2002 Horrigan FT, Aldrich RW. Erratum: (Journal of General Physiology (September 2002) 120:3 (267-305)) The Journal of General Physiology. 120. DOI: 10.1085/Jgp.20020919120267  1
2001 Petkov GV, Bonev AD, Heppner TJ, Brenner R, Aldrich RW, Nelson MT. Beta1-subunit of the Ca2+-activated K+ channel regulates contractile activity of mouse urinary bladder smooth muscle. The Journal of Physiology. 537: 443-52. PMID 11731577 DOI: 10.1111/J.1469-7793.2001.00443.X  1
2001 Aldrich RW. Fifty years of inactivation. Nature. 411: 643-4. PMID 11395746 DOI: 10.1038/35079705  1
2000 Cui J, Aldrich RW. Allosteric linkage between voltage and Ca(2+)-dependent activation of BK-type mslo1 K(+) channels. Biochemistry. 39: 15612-9. PMID 11112549 DOI: 10.1021/bi001509+  1
2000 Brenner R, Peréz GJ, Bonev AD, Eckman DM, Kosek JC, Wiler SW, Patterson AJ, Nelson MT, Aldrich RW. Vasoregulation by the beta1 subunit of the calcium-activated potassium channel. Nature. 407: 870-6. PMID 11057658 DOI: 10.1038/35038011  1
2000 Cox DH, Aldrich RW. Role of the beta1 subunit in large-conductance Ca(2+)-activated K(+) channel gating energetics. Mechanisms of enhanced Ca(2+) sensitivity. The Journal of General Physiology. 116: 411-32. PMID 10962017 DOI: 10.1085/jgp.116.3.411  1
2000 Middendorf TR, Aldrich RW. Effects of ultraviolet modification on the gating energetics of cyclic nucleotide-gated channels. The Journal of General Physiology. 116: 253-82. PMID 10919870 DOI: 10.1085/jgp.116.2.253  1
2000 Middendorf TR, Aldrich RW, Baylor DA. Modification of cyclic nucleotide-gated ion channels by ultraviolet light. The Journal of General Physiology. 116: 227-52. PMID 10919869 DOI: 10.1085/jgp.116.2.227  1
2000 Brenner R, Jegla TJ, Wickenden A, Liu Y, Aldrich RW. Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4. The Journal of Biological Chemistry. 275: 6453-61. PMID 10692449 DOI: 10.1074/Jbc.275.9.6453  1
2000 Talukder G, Aldrich RW. Complex voltage-dependent behavior of single unliganded calcium-sensitive potassium channels. Biophysical Journal. 78: 761-72. PMID 10653789 DOI: 10.1016/S0006-3495(00)76634-3  1
1999 Horrigan FT, Aldrich RW. Allosteric voltage gating of potassium channels II. Mslo channel gating charge movement in the absence of Ca(2+). The Journal of General Physiology. 114: 305-36. PMID 10436004 DOI: 10.1085/jgp.114.2.305  1
1999 Horrigan FT, Cui J, Aldrich RW. Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+). The Journal of General Physiology. 114: 277-304. PMID 10436003 DOI: 10.1085/jgp.114.2.277  1
1999 Kanevsky M, Aldrich RW. Determinants of voltage-dependent gating and open-state stability in the S5 segment of Shaker potassium channels. The Journal of General Physiology. 114: 215-42. PMID 10435999 DOI: 10.1085/Jgp.114.2.215  1
1999 Zagrovic B, Aldrich R. For the latest information, tune to channel KcsA. Science (New York, N.Y.). 285: 59, 61. PMID 10428704 DOI: 10.1126/Science.285.5424.59  1
1999 Zei PC, Ogielska EM, Hoshi T, Aldrich RW. Effects on ion permeation with hydrophobic substitutions at a residue in Shaker S6 that interacts with a signature sequence amino acid. Annals of the New York Academy of Sciences. 868: 458-64. PMID 10414322 DOI: 10.1111/j.1749-6632.1999.tb11314.x  1
1999 Ledwell JL, Aldrich RW. Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. The Journal of General Physiology. 113: 389-414. PMID 10051516 DOI: 10.1085/jgp.113.3.389  1
1999 Ogielska EM, Aldrich RW. Functional consequences of a decreased potassium affinity in a potassium channel pore. Ion interactions and C-type inactivation. The Journal of General Physiology. 113: 347-58. PMID 9925829 DOI: 10.1085/jgp.113.2.347  1
1998 Zei PC, Aldrich RW. Voltage-dependent gating of single wild-type and S4 mutant KAT1 inward rectifier potassium channels. The Journal of General Physiology. 112: 679-713. PMID 9834140 DOI: 10.1085/jgp.112.6.679  1
1998 Ogielska EM, Aldrich RW. A mutation in S6 of Shaker potassium channels decreases the K+ affinity of an ion binding site revealing ion-ion interactions in the pore. The Journal of General Physiology. 112: 243-57. PMID 9689030 DOI: 10.1085/jgp.112.2.243  1
1998 Smith-Maxwell CJ, Ledwell JL, Aldrich RW. Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation. The Journal of General Physiology. 111: 421-39. PMID 9482709 DOI: 10.1085/jgp.111.3.421  1
1998 Smith-Maxwell CJ, Ledwell JL, Aldrich RW. Role of the S4 in cooperativity of voltage-dependent potassium channel activation. The Journal of General Physiology. 111: 399-420. PMID 9482708 DOI: 10.1085/jgp.111.3.399  1
1997 Cox DH, Cui J, Aldrich RW. Allosteric gating of a large conductance Ca-activated K+ channel. The Journal of General Physiology. 110: 257-81. PMID 9276753 DOI: 10.1085/jgp.110.3.257  1
1997 Cui J, Cox DH, Aldrich RW. Intrinsic voltage dependence and Ca2+ regulation of mslo large conductance Ca-activated K+ channels. The Journal of General Physiology. 109: 647-73. PMID 9154910 DOI: 10.1085/jgp.109.5.647  1
1997 Cox DH, Cui J, Aldrich RW. Separation of gating properties from permeation and block in mslo large conductance Ca-activated K+ channels. The Journal of General Physiology. 109: 633-46. PMID 9154909 DOI: 10.1085/jgp.109.5.633  1
1997 Stocker JW, Nadasdi L, Aldrich RW, Tsien RW. Preferential interaction of omega-conotoxins with inactivated N-type Ca2+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3002-13. PMID 9096136  1
1997 Stocker JW, Nadasdi L, Aldrich RW, Tsien RW. Preferential Interaction of ω-Conotoxins with Inactivated N-type Ca2+ Channels The Journal of Neuroscience. 17: 3002-3013. DOI: 10.1523/Jneurosci.17-09-03002.1997  1
1996 Zhang JF, Ellinor PT, Aldrich RW, Tsien RW. Multiple structural elements in voltage-dependent Ca2+ channels support their inhibition by G proteins. Neuron. 17: 991-1003. PMID 8938130 DOI: 10.1016/S0896-6273(00)80229-9  1
1996 Miller AG, Aldrich RW. Conversion of a delayed rectifier K+ channel to a voltage-gated inward rectifier K+ channel by three amino acid substitutions. Neuron. 16: 853-8. PMID 8608003 DOI: 10.1016/S0896-6273(00)80105-1  1
1995 Ogielska EM, Zagotta WN, Hoshi T, Heinemann SH, Haab J, Aldrich RW. Cooperative subunit interactions in C-type inactivation of K channels. Biophysical Journal. 69: 2449-57. PMID 8599651 DOI: 10.1016/S0006-3495(95)80114-1  1
1994 Zagotta WN, Hoshi T, Aldrich RW. Shaker potassium channel gating. III: Evaluation of kinetic models for activation. The Journal of General Physiology. 103: 321-62. PMID 8189208 DOI: 10.1085/Jgp.103.2.321  1
1994 Zagotta WN, Hoshi T, Dittman J, Aldrich RW. Shaker potassium channel gating. II: Transitions in the activation pathway. The Journal of General Physiology. 103: 279-319. PMID 8189207 DOI: 10.1085/Jgp.103.2.279  1
1994 Hoshi T, Zagotta WN, Aldrich RW. Shaker potassium channel gating. I: Transitions near the open state. The Journal of General Physiology. 103: 249-78. PMID 8189206 DOI: 10.1085/Jgp.103.2.249  1
1994 Drain P, Dubin AE, Aldrich RW. Regulation of Shaker K+ channel inactivation gating by the cAMP-dependent protein kinase. Neuron. 12: 1097-109. PMID 8185946 DOI: 10.1016/0896-6273(94)90317-4  1
1994 Zhang JF, Ellinor PT, Aldrich RW, Tsien RW. Molecular determinants of voltage-dependent inactivation in calcium channels. Nature. 372: 97-100. PMID 7969428 DOI: 10.1038/372097a0  1
1994 Aldrich RW. Potassium channels. New channel subunits are a turn-off. Current Biology : Cb. 4: 839-40. PMID 7865026 DOI: 10.1016/S0960-9822(00)00187-1  1
1993 Aldrich R. Advent of a new family Nature. 362: 107-108. PMID 8450880 DOI: 10.1038/362107A0  1
1993 Murrell-Lagnado RD, Aldrich RW. Energetics of Shaker K channels block by inactivation peptides. The Journal of General Physiology. 102: 977-1003. PMID 8133246 DOI: 10.1085/Jgp.102.6.977  1
1993 Murrell-Lagnado RD, Aldrich RW. Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides. The Journal of General Physiology. 102: 949-75. PMID 8133245 DOI: 10.1085/Jgp.102.6.949  1
1993 López-Barneo J, Hoshi T, Heinemann SH, Aldrich RW. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors & Channels. 1: 61-71. PMID 8081712  1
1993 MacKinnon R, Aldrich RW, Lee AW. Functional stoichiometry of Shaker potassium channel inactivation. Science (New York, N.Y.). 262: 757-9. PMID 7694359 DOI: 10.1126/Science.7694359  1
1992 Foster CD, Chung S, Zagotta WN, Aldrich RW, Levitan IB. A peptide derived from the Shaker B K+ channel produces short and long blocks of reconstituted Ca(2+)-dependent K+ channels. Neuron. 9: 229-36. PMID 1497892 DOI: 10.1016/0896-6273(92)90162-7  1
1992 Germeraad S, O'Dowd D, Aldrich RW. Functional assay of a putative Drosophila sodium channel gene in homozygous deficiency neurons. Journal of Neurogenetics. 8: 1-16. PMID 1313499 DOI: 10.3109/01677069209167268  1
1991 Choi KL, Aldrich RW, Yellen G. Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 88: 5092-5. PMID 2052588 DOI: 10.1073/Pnas.88.12.5092  1
1991 Hoshi T, Zagotta WN, Aldrich RW. Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region. Neuron. 7: 547-56. PMID 1931050 DOI: 10.1016/0896-6273(91)90367-9  1
1991 McEachern AE, Shelton ER, Bhakta S, Obernolte R, Bach C, Zuppan P, Fujisaki J, Aldrich RW, Jarnagin K. Expression cloning of a rat B2 bradykinin receptor. Proceedings of the National Academy of Sciences of the United States of America. 88: 7724-8. PMID 1715575 DOI: 10.1073/Pnas.88.17.7724  1
1990 Zagotta WN, Aldrich RW. Alterations in activation gating of single Shaker A-type potassium channels by the Sh5 mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1799-810. PMID 2355250 DOI: 10.1523/Jneurosci.10-06-01799.1990  1
1990 Zagotta WN, Aldrich RW. Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle. The Journal of General Physiology. 95: 29-60. PMID 2299331 DOI: 10.1085/Jgp.95.1.29  1
1990 Garber SS, Hoshi T, Aldrich RW. Interaction of forskolin with voltage-gated K+ channels in PC12 cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3361-8. PMID 2213145 DOI: 10.1523/Jneurosci.10-10-03361.1990  1
1990 Solc CK, Aldrich RW. Gating of single non-Shaker A-type potassium channels in larval Drosophila neurons. The Journal of General Physiology. 96: 135-65. PMID 2212978 DOI: 10.1085/Jgp.96.1.135  1
1990 Aldrich RW, Hoshi T, Zagotta WN. Differences in gating among amino-terminal variants of Shaker potassium channels. Cold Spring Harbor Symposia On Quantitative Biology. 55: 19-27. PMID 2132814 DOI: 10.1101/Sqb.1990.055.01.005  1
1990 Zagotta WN, Hoshi T, Aldrich RW. Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB. Science (New York, N.Y.). 250: 568-71. PMID 2122520 DOI: 10.1126/Science.2122520  1
1990 Hoshi T, Zagotta WN, Aldrich RW. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science (New York, N.Y.). 250: 533-8. PMID 2122519 DOI: 10.1126/Science.2122519  1
1990 Aldrich RW. Potassium channels. Mixing and matching. Nature. 345: 475-6. PMID 2112228 DOI: 10.1038/345475a0  1
1989 O'Dowd DK, Germeraad SE, Aldrich RW. Alterations in the expression and gating of Drosophila sodium channels by mutations in the para gene. Neuron. 2: 1301-11. PMID 2560637 DOI: 10.1016/0896-6273(89)90068-8  1
1989 Zagotta WN, Hoshi T, Aldrich RW. Gating of single Shaker potassium channels in Drosophila muscle and in Xenopus oocytes injected with Shaker mRNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 7243-7. PMID 2506548 DOI: 10.1073/Pnas.86.18.7243  1
1989 Zagotta WN, Germeraad S, Garber SS, Hoshi T, Aldrich RW. Properties of ShB A-type potassium channels expressed in Shaker mutant Drosophila by germline transformation. Neuron. 3: 773-82. PMID 2484347 DOI: 10.1016/0896-6273(89)90246-8  1
1989 Garber SS, Hoshi T, Aldrich RW. Regulation of ionic currents in pheochromocytoma cells by nerve growth factor and dexamethasone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3976-87. PMID 2479727 DOI: 10.1523/Jneurosci.09-11-03976.1989  1
1989 Aldrich RW. Ion channels. Mutating and gating. Nature. 339: 578-9. PMID 2471940 DOI: 10.1038/339578a0  1
1988 Solc CK, Aldrich RW. Voltage-gated potassium channels in larval CNS neurons of Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2556-70. PMID 3249242  1
1988 Zagotta WN, Brainard MS, Aldrich RW. Single-channel analysis of four distinct classes of potassium channels in Drosophila muscle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 4765-79. PMID 3199204 DOI: 10.1523/Jneurosci.08-12-04765.1988  1
1988 O'Dowd DK, Aldrich RW. Voltage-clamp analysis of sodium channels in wild-type and mutant Drosophila neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3633-43. PMID 2848103 DOI: 10.1523/Jneurosci.08-10-03633.1988  1
1988 Hoshi T, Garber SS, Aldrich RW. Effect of forskolin on voltage-gated K+ channels is independent of adenylate cyclase activation. Science (New York, N.Y.). 240: 1652-5. PMID 2454506 DOI: 10.1126/Science.2454506  1
1988 Hoshi T, Aldrich RW. Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells. The Journal of General Physiology. 91: 73-106. PMID 2449514 DOI: 10.1085/Jgp.91.1.73  1
1988 Hoshi T, Aldrich RW. Gating kinetics of four classes of voltage-dependent K+ channels in pheochromocytoma cells. The Journal of General Physiology. 91: 107-31. PMID 2449512 DOI: 10.1085/Jgp.91.1.107  1
1987 Hollingworth S, Aldrich RW, Baylor SM. In vitro calibration of the equilibrium reactions of the metallochromic indicator dye antipyrylazo III with calcium. Biophysical Journal. 51: 383-93. PMID 3567312 DOI: 10.1016/S0006-3495(87)83360-X  1
1987 Solc CK, Zagotta WN, Aldrich RW. Single-channel and genetic analyses reveal two distinct A-type potassium channels in Drosophila. Science (New York, N.Y.). 236: 1094-8. PMID 2437657 DOI: 10.1126/Science.2437657  1
1987 Aldrich RW, Stevens CF. Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 418-31. PMID 2434628 DOI: 10.1523/Jneurosci.07-02-00418.1987  1
1986 Aldrich RW. Voltage-dependent gating of sodium channels: towards an integrated approach Trends in Neurosciences. 9: 82-86. DOI: 10.1016/0166-2236(86)90028-7  1
1985 Aldrich R. Molecular biophysics: ionic channels of excitable membranes. Science. 228: 867-868. PMID 17815046 DOI: 10.1126/Science.228.4701.867  0.01
1983 Aldrich RW, Stevens CF. Inactivation of open and closed sodium channels determined separately. Cold Spring Harbor Symposia On Quantitative Biology. 48: 147-53. PMID 6327148 DOI: 10.1101/Sqb.1983.048.01.017  1
1983 Aldrich RW, Corey DP, Stevens CF. A reinterpretation of mammalian sodium channel gating based on single channel recording. Nature. 306: 436-41. PMID 6316158 DOI: 10.1038/306436a0  1
1981 Aldrich RW. Inactivation of voltage-gated delayed potassium current in molluscan neurons. A kinetic model. Biophysical Journal. 36: 519-32. PMID 6275919 DOI: 10.1016/S0006-3495(81)84750-9  1
1980 Gibbons MD, Swab JM, Davern WE, Winn ML, Brusgard TC, Aldrich RW. ADVANCES IN InSb CHARGE INJECTION DEVICE (CID) FOCAL PLANES Proceedings of the Society of Photo-Optical Instrumentation Engineers. 225: 55-63. DOI: 10.1117/12.958703  1
1979 Aldrich RW, Getting PA, Thompson SH. Mechanism of frequency-dependent broadening of molluscan neurone soma spikes. The Journal of Physiology. 291: 531-44. PMID 480247 DOI: 10.1113/jphysiol.1979.sp012829  1
1979 Aldrich RW, Getting PA, Thompson SH. Inactivation of delayed outward current in molluscan neurone somata. The Journal of Physiology. 291: 507-30. PMID 480244 DOI: 10.1113/jphysiol.1979.sp012828  1
1979 Gibbons MD, Swab JM, Davern WE, Aldrich RW. PERFORMANCE EFFICIENCY OF InSb CHARGE INJECTION DEVICES (CID) Proceedings of the Society of Photo-Optical Instrumentation Engineers. 203: 158-165. DOI: 10.1117/12.958137  1
1969 Mogar RE, Aldrich RW. The use of psychedelic agents with autistic schizophrenic children. Behavioral Neuropsychiatry. 1: 44-50. PMID 5374546  1
1969 Wilson WM, Aldrich RW. The Mendocino Drug Abuse Program Journal of Psychoactive Drugs. 2: 102-104. DOI: 10.1080/02791072.1969.10524421  1
1963 Ing SW, Aldrich RW, Morrison RE, Alt LL. Gettering of Metallic Impurities from Planar Silicon Diodes Journal of the Electrochemical Society. 110: 533-537. DOI: 10.1149/1.2425808  1
1960 Lesk IA, Holonyak N, Aldrich RW, Brouillette JW, Ghandi SK. A Categorization of the Solid-State Device Aspects of Microsystems Electronics Proceedings of the Ire. 48: 1833-1841. DOI: 10.1109/JRPROC.1960.287416  1
1959 Aldrich RW, Holonyak N. Two-terminal asymmetrical and symmetrical silicon negative resistance switches Journal of Applied Physics. 30: 1819-1824. DOI: 10.1063/1.1735062  1
1958 Aldrich RW, Lanzl RH, Maxwell DE, Percival JO, Waldner M. An 85-Watt Dissipation Silicon Power Transistor Ire Transactions On Electron Devices. 5: 211-215. DOI: 10.1109/T-ED.1958.14424  1
1958 Aldrich RW, Holonyak N. Multiterminal P-N-P-N Switches Proceedings of the Ire. 46: 1236-1239. DOI: 10.1109/JRPROC.1958.286909  1
1954 Aldrich RW, Lesk IA. The double-base diode: A semiconductor thyratron analog Transactions of the Ire Professional Group On Electron Devices. 1: 24-27. DOI: 10.1109/T-ED.1954.13952  1
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