Year |
Citation |
Score |
2024 |
Tucker N, Reddien P, Hersh B, Lee D, Liu MHX, Horvitz HR. The pro-apoptotic function of the BCL-2 homolog CED-9 requires interaction with the APAF-1 homolog CED-4. Science Advances. 10: eadn0325. PMID 39383227 DOI: 10.1126/sciadv.adn0325 |
0.793 |
|
2023 |
Doi A, Suarez GD, Droste R, Horvitz HR. A DEAD-box helicase drives the partitioning of a pro-differentiation NAB protein into nuclear foci. Nature Communications. 14: 6593. PMID 37852948 DOI: 10.1038/s41467-023-42345-9 |
0.33 |
|
2023 |
Kochersberger A, Torkashvand MM, Lee D, Baskoylu S, Sengupta T, Koonce N, Emerson CE, Patel NV, Colón-Ramos D, Flavell S, Horvitz HR, Venkatachalam V, Hammarlund M. Programmed Cell Death Modifies Neural Circuits and Tunes Intrinsic Behavior. Biorxiv : the Preprint Server For Biology. PMID 37745399 DOI: 10.1101/2023.09.11.557249 |
0.798 |
|
2022 |
Saul J, Hirose T, Horvitz HR. The transcriptional corepressor CTBP-1 acts with the SOX family transcription factor EGL-13 to maintain AIA interneuron cell identity in . Elife. 11. PMID 35119366 DOI: 10.7554/eLife.74557 |
0.455 |
|
2021 |
Sando SR, Bhatla N, Lee ELQ, Horvitz HR. An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction. Elife. 10. PMID 34212858 DOI: 10.7554/eLife.59341 |
0.26 |
|
2021 |
Dwivedi VK, Pardo-Pastor C, Droste R, Kong JN, Tucker N, Denning DP, Rosenblatt J, Horvitz HR. Replication stress promotes cell elimination by extrusion. Nature. PMID 33953402 DOI: 10.1038/s41586-021-03526-y |
0.374 |
|
2021 |
Ghosh DD, Lee D, Jin X, Horvitz HR, Nitabach MN. discriminates colors to guide foraging. Science (New York, N.Y.). 371: 1059-1063. PMID 33674494 DOI: 10.1126/science.abd3010 |
0.391 |
|
2020 |
Burkhart KB, Sando SR, Corrionero A, Horvitz HR. H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect. Current Biology : Cb. PMID 32470364 DOI: 10.1016/j.cub.2020.04.046 |
0.399 |
|
2019 |
Cohn J, Dwivedi V, Valperga G, Zarate N, de Bono M, Horvitz HR, Pierce JT. Activity-Dependent Regulation of the Proapoptotic BH3-Only Gene in a Living Neuron Pair in . G3 (Bethesda, Md.). PMID 31519744 DOI: 10.1534/G3.119.400654 |
0.732 |
|
2018 |
Burton NO, Dwivedi VK, Burkhart KB, Kaplan REW, Baugh LR, Horvitz HR. Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response. Nature Communications. 9: 5152. PMID 30514845 DOI: 10.1038/S41467-018-07640-W |
0.63 |
|
2018 |
Pender CL, Horvitz HR. Hypoxia-inducible factor cell non-autonomously regulates stress responses and behavior via a nuclear receptor. Elife. 7. PMID 30010540 DOI: 10.7554/eLife.36828 |
0.441 |
|
2018 |
Corrionero A, Horvitz HR. A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis. Current Biology : Cb. PMID 29731301 DOI: 10.1016/j.cub.2018.03.063 |
0.483 |
|
2018 |
Engert CG, Droste R, van Oudenaarden A, Horvitz HR. A C. elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility. Plos Genetics. 14: e1007295. PMID 29702639 DOI: 10.1371/journal.pgen.1007295 |
0.459 |
|
2018 |
Van Bael S, Watteyne J, Boonen K, De Haes W, Menschaert G, Ringstad N, Horvitz HR, Schoofs L, Husson S, Temmerman L. Mass Spectrometric Evidence for Neuropeptide-Amidating Enzymes in. The Journal of Biological Chemistry. PMID 29487130 DOI: 10.1074/jbc.RA117.000731 |
0.725 |
|
2018 |
Pender CL, Horvitz HR. Author response: Hypoxia-inducible factor cell non-autonomously regulates C. elegans stress responses and behavior via a nuclear receptor Elife. DOI: 10.7554/Elife.36828.026 |
0.399 |
|
2017 |
Driscoll K, Stanfield GM, Droste R, Horvitz HR. Presumptive TRP channel CED-11 promotes cell volume decrease and facilitates degradation of apoptotic cells in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760991 DOI: 10.1073/pnas.1705084114 |
0.796 |
|
2017 |
Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, ... ... Horvitz HR, et al. US immigration order strikes against biotech. Nature Biotechnology. 35: 204-206. PMID 28267733 DOI: 10.1038/Nbt.3824 |
0.509 |
|
2017 |
Luo S, Horvitz HR. The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage. Current Biology : Cb. 27: 661-672. PMID 28238659 DOI: 10.1016/j.cub.2017.01.056 |
0.465 |
|
2017 |
Burton NO, Furuta T, Webster AK, Kaplan RE, Baugh LR, Arur S, Horvitz HR. Insulin-like signalling to the maternal germline controls progeny response to osmotic stress. Nature Cell Biology. 19: 252-257. PMID 28166192 DOI: 10.1038/Ncb3470 |
0.635 |
|
2016 |
Johnsen HL, Horvitz HR. Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans. Bmc Biology. 14: 39. PMID 27185172 DOI: 10.1186/s12915-016-0262-5 |
0.463 |
|
2016 |
Paquin N, Murata Y, Froehlich A, Omura DT, Ailion M, Pender CL, Constantine-Paton M, Horvitz HR. The Conserved VPS-50 Protein Functions in Dense-Core Vesicle Maturation and Acidification and Controls Animal Behavior. Current Biology : Cb. 26: 862-71. PMID 26948874 DOI: 10.1016/J.Cub.2016.01.049 |
0.417 |
|
2015 |
Peters OM, Cabrera GT, Tran H, Gendron TF, McKeon JE, Metterville J, Weiss A, Wightman N, Salameh J, Kim J, Sun H, Boylan KB, Dickson D, Kennedy Z, Lin Z, ... ... Horvitz HR, et al. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice. Neuron. 88: 902-909. PMID 26637797 DOI: 10.1016/J.Neuron.2015.11.018 |
0.393 |
|
2015 |
Bhatla N, Droste R, Sando SR, Huang A, Horvitz HR. Distinct Neural Circuits Control Rhythm Inhibition and Spitting by the Myogenic Pharynx of C. elegans. Current Biology : Cb. 25: 2075-89. PMID 26212880 DOI: 10.1016/j.cub.2015.06.052 |
0.381 |
|
2015 |
Ma DK, Li Z, Lu AY, Sun F, Chen S, Rothe M, Menzel R, Sun F, Horvitz HR. Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids. Cell. 161: 1152-63. PMID 25981666 DOI: 10.1016/J.Cell.2015.04.026 |
0.612 |
|
2015 |
Bhatla N, Horvitz HR. Light and hydrogen peroxide inhibit C. elegans Feeding through gustatory receptor orthologs and pharyngeal neurons. Neuron. 85: 804-18. PMID 25640076 DOI: 10.1016/j.neuron.2014.12.061 |
0.37 |
|
2015 |
Bhatla N, Droste R, Sando SR, Huang A, Horvitz HR. Distinct neural circuits control rhythm inhibition and spitting by the myogenic pharynx of C. elegans Current Biology. 25: 2075-2089. DOI: 10.1016/j.cub.2015.06.052 |
0.262 |
|
2014 |
Hirose T, Horvitz HR. The translational regulators GCN-1 and ABCF-3 act together to promote apoptosis in C. elegans. Plos Genetics. 10: e1004512. PMID 25101958 DOI: 10.1371/journal.pgen.1004512 |
0.541 |
|
2014 |
Rawson RL, Yam L, Weimer RM, Bend EG, Hartwieg E, Horvitz HR, Clark SG, Jorgensen EM. Axons degenerate in the absence of mitochondria in C. elegans. Current Biology : Cb. 24: 760-5. PMID 24631238 DOI: 10.1016/J.Cub.2014.02.025 |
0.777 |
|
2014 |
de la Cruz IP, Ma L, Horvitz HR. The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9. Plos Genetics. 10: e1004175. PMID 24586202 DOI: 10.1371/journal.pgen.1004175 |
0.374 |
|
2013 |
Hirose T, Horvitz HR. An Sp1 transcription factor coordinates caspase-dependent and -independent apoptotic pathways. Nature. 500: 354-8. PMID 23851392 DOI: 10.1038/nature12329 |
0.513 |
|
2013 |
Suzuki J, Denning DP, Imanishi E, Horvitz HR, Nagata S. Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science (New York, N.Y.). 341: 403-6. PMID 23845944 DOI: 10.1126/science.1236758 |
0.469 |
|
2013 |
Ma DK, Rothe M, Zheng S, Bhatla N, Pender CL, Menzel R, Horvitz HR. Cytochrome P450 drives a HIF-regulated behavioral response to reoxygenation by C. elegans. Science (New York, N.Y.). 341: 554-8. PMID 23811225 DOI: 10.1126/science.1235753 |
0.601 |
|
2013 |
Denning DP, Hatch V, Horvitz HR. Both the caspase CSP-1 and a caspase-independent pathway promote programmed cell death in parallel to the canonical pathway for apoptosis in Caenorhabditis elegans. Plos Genetics. 9: e1003341. PMID 23505386 DOI: 10.1371/journal.pgen.1003341 |
0.496 |
|
2012 |
Anderson C, Zhou S, Sawin E, Horvitz HR, Hurwitz ME. SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function. Plos Genetics. 8: e1003115. PMID 23271977 DOI: 10.1371/Journal.Pgen.1003115 |
0.53 |
|
2012 |
Emtage L, Aziz-Zaman S, Padovan-Merhar O, Horvitz HR, Fang-Yen C, Ringstad N. IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a G(o) signaling pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16285-95. PMID 23152612 DOI: 10.1523/JNEUROSCI.2667-12.2012 |
0.705 |
|
2012 |
Gürel G, Gustafson MA, Pepper JS, Horvitz HR, Koelle MR. Receptors and other signaling proteins required for serotonin control of locomotion in Caenorhabditis elegans. Genetics. 192: 1359-71. PMID 23023001 DOI: 10.1534/Genetics.112.142125 |
0.732 |
|
2012 |
Ma L, Gao X, Luo J, Huang L, Teng Y, Horvitz HR. The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. Plos Genetics. 8: e1002827. PMID 22829783 DOI: 10.1371/journal.pgen.1002827 |
0.498 |
|
2012 |
Denning DP, Hatch V, Horvitz HR. Programmed elimination of cells by caspase-independent cell extrusion in C. elegans. Nature. 488: 226-30. PMID 22801495 DOI: 10.1038/nature11240 |
0.521 |
|
2012 |
Omura DT, Clark DA, Samuel AD, Horvitz HR. Dopamine signaling is essential for precise rates of locomotion by C. elegans. Plos One. 7: e38649. PMID 22719914 DOI: 10.1371/journal.pone.0038649 |
0.394 |
|
2012 |
Boulias K, Horvitz HR. The C. elegans microRNA mir-71 acts in neurons to promote germline-mediated longevity through regulation of DAF-16/FOXO. Cell Metabolism. 15: 439-50. PMID 22482727 DOI: 10.1016/j.cmet.2012.02.014 |
0.392 |
|
2012 |
Ma DK, Vozdek R, Bhatla N, Horvitz HR. CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans. Neuron. 73: 925-40. PMID 22405203 DOI: 10.1016/j.neuron.2011.12.037 |
0.64 |
|
2012 |
Klees E, Horvitz HR. Biomedical Consulting Agreements: The Good, the Bad, and the Ugly Science. DOI: 10.1126/Science.Caredit.A1200114 |
0.292 |
|
2011 |
Saffer AM, Kim DH, van Oudenaarden A, Horvitz HR. The Caenorhabditis elegans synthetic multivulva genes prevent ras pathway activation by tightly repressing global ectopic expression of lin-3 EGF. Plos Genetics. 7: e1002418. PMID 22242000 DOI: 10.1371/journal.pgen.1002418 |
0.798 |
|
2011 |
Nakano S, Stillman B, Horvitz HR. Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans. Cell. 147: 1525-36. PMID 22177093 DOI: 10.1016/J.Cell.2011.11.053 |
0.699 |
|
2011 |
Ma L, Tan Z, Teng Y, Hoersch S, Horvitz HR. In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans. Rna (New York, N.Y.). 17: 2201-11. PMID 22033331 DOI: 10.1261/rna.027458.111 |
0.442 |
|
2011 |
Harris DT, Horvitz HR. MAB-10/NAB acts with LIN-29/EGR to regulate terminal differentiation and the transition from larva to adult in C. elegans. Development (Cambridge, England). 138: 4051-62. PMID 21862562 DOI: 10.1242/dev.065417 |
0.507 |
|
2011 |
Tabuchi TM, Deplancke B, Osato N, Zhu LJ, Barrasa MI, Harrison MM, Horvitz HR, Walhout AJ, Hagstrom KA. Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex. Plos Genetics. 7: e1002074. PMID 21589891 DOI: 10.1371/Journal.Pgen.1002074 |
0.679 |
|
2011 |
Galvin BD, Denning DP, Horvitz HR. SPK-1, an SR protein kinase, inhibits programmed cell death in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 108: 1998-2003. PMID 21245325 DOI: 10.1073/pnas.1018805108 |
0.548 |
|
2011 |
Davison EM, Saffer AM, Huang LS, DeModena J, Sternberg PW, Horvitz HR. The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination. Genetics. 187: 803-15. PMID 21196525 DOI: 10.1534/genetics.110.124487 |
0.796 |
|
2011 |
Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM, Horvitz HR, Sternberg PW, Ringstad N. Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 108: 254-9. PMID 21173231 DOI: 10.1073/Pnas.1017354108 |
0.766 |
|
2011 |
Korzelius J, The I, Ruijtenberg S, Portegijs V, Xu H, Horvitz HR, van den Heuvel S. C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability. Developmental Biology. 350: 358-69. PMID 21146520 DOI: 10.1016/J.Ydbio.2010.12.009 |
0.468 |
|
2010 |
Nakano S, Ellis RE, Horvitz HR. Otx-dependent expression of proneural bHLH genes establishes a neuronal bilateral asymmetry in C. elegans. Development (Cambridge, England). 137: 4017-27. PMID 21041366 DOI: 10.1242/Dev.058834 |
0.767 |
|
2010 |
Berdichevsky A, Nedelcu S, Boulias K, Bishop NA, Guarente L, Horvitz HR. 3-Ketoacyl thiolase delays aging of Caenorhabditis elegans and is required for lifespan extension mediated by sir-2.1. Proceedings of the National Academy of Sciences of the United States of America. 107: 18927-32. PMID 20956318 DOI: 10.1073/pnas.1013854107 |
0.46 |
|
2010 |
Hirose T, Galvin BD, Horvitz HR. Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 107: 15479-84. PMID 20713707 DOI: 10.1073/pnas.1010023107 |
0.527 |
|
2010 |
Alvarez-Saavedra E, Horvitz HR. Many families of C. elegans microRNAs are not essential for development or viability. Current Biology : Cb. 20: 367-73. PMID 20096582 DOI: 10.1016/j.cub.2009.12.051 |
0.362 |
|
2009 |
Jospin M, Qi YB, Stawicki TM, Boulin T, Schuske KR, Horvitz HR, Bessereau JL, Jorgensen EM, Jin Y. A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans. Plos Biology. 7: e1000265. PMID 20027209 DOI: 10.1371/Journal.Pbio.1000265 |
0.783 |
|
2009 |
Ma L, Horvitz HR. Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivo. Plos Genetics. 5: e1000708. PMID 19893607 DOI: 10.1371/journal.pgen.1000708 |
0.449 |
|
2009 |
Ringstad N, Abe N, Horvitz HR. Ligand-gated chloride channels are receptors for biogenic amines in C. elegans. Science (New York, N.Y.). 325: 96-100. PMID 19574391 DOI: 10.1126/science.1169243 |
0.707 |
|
2009 |
Landers JE, Melki J, Meininger V, Glass JD, van den Berg LH, van Es MA, Sapp PC, van Vught PW, McKenna-Yasek DM, Blauw HM, Cho TJ, Polak M, Shi L, Wills AM, Broom WJ, ... ... Horvitz HR, et al. Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 9004-9. PMID 19451621 DOI: 10.1073/Pnas.0812937106 |
0.382 |
|
2009 |
Hurwitz ME, Vanderzalm PJ, Bloom L, Goldman J, Garriga G, Horvitz HR. Abl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegans. Plos Biology. 7: e99. PMID 19402756 DOI: 10.1371/Journal.Pbio.1000099 |
0.82 |
|
2009 |
Kwiatkowski TJ, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Valdmanis P, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, ... ... Horvitz HR, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science (New York, N.Y.). 323: 1205-8. PMID 19251627 DOI: 10.1126/Science.1166066 |
0.388 |
|
2009 |
Vanderzalm PJ, Pandey A, Hurwitz ME, Bloom L, Horvitz HR, Garriga G. C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development. Development (Cambridge, England). 136: 1201-10. PMID 19244282 DOI: 10.1242/Dev.026666 |
0.805 |
|
2009 |
Yu H, Seah A, Herman MA, Ferguson EL, Horvitz HR, Sternberg PW. Wnt and EGF pathways act together to induce C. elegans male hook development. Developmental Biology. 327: 419-32. PMID 19154732 DOI: 10.1016/J.Ydbio.2008.12.023 |
0.789 |
|
2009 |
Simpson CL, Lemmens R, Miskiewicz K, Broom WJ, Hansen VK, van Vught PW, Landers JE, Sapp P, Van Den Bosch L, Knight J, Neale BM, Turner MR, Veldink JH, Ophoff RA, Tripathi VB, ... ... Horvitz HR, et al. Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration. Human Molecular Genetics. 18: 472-81. PMID 18996918 DOI: 10.1093/Hmg/Ddn375 |
0.465 |
|
2009 |
Hurwitz ME, Vanderzalm PJ, Bloom L, Goldman J, Garriga G, Horvitz HR. Correction: Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans Plos Biology. 7. DOI: 10.1371/Annotation/2259F958-A68E-4E57-92B5-2Ef003070Cf1 |
0.766 |
|
2008 |
Ringstad N, Horvitz HR. FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans. Nature Neuroscience. 11: 1168-76. PMID 18806786 DOI: 10.1038/nn.2186 |
0.756 |
|
2008 |
Andersen EC, Saffer AM, Horvitz HR. Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates. Genetics. 179: 2001-12. PMID 18689876 DOI: 10.1534/Genetics.108.092197 |
0.823 |
|
2008 |
Galvin BD, Kim S, Horvitz HR. Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33. Genetics. 179: 403-17. PMID 18458102 DOI: 10.1534/genetics.108.087221 |
0.567 |
|
2008 |
Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz HR, Schier AF, Dulac C. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 57: 41-55. PMID 18184563 DOI: 10.1016/J.Neuron.2007.11.018 |
0.253 |
|
2007 |
Miska EA, Alvarez-Saavedra E, Abbott AL, Lau NC, Hellman AB, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. Plos Genetics. 3: e215. PMID 18085825 DOI: 10.1371/Journal.Pgen.0030215 |
0.72 |
|
2007 |
Schwartz HT, Horvitz HR. The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9. Genes & Development. 21: 3181-94. PMID 18056428 DOI: 10.1101/gad.1607007 |
0.529 |
|
2007 |
Eimer S, Gottschalk A, Hengartner M, Horvitz HR, Richmond J, Schafer WR, Bessereau JL. Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50. The Embo Journal. 26: 4313-23. PMID 17853888 DOI: 10.1038/Sj.Emboj.7601858 |
0.593 |
|
2007 |
Andersen EC, Horvitz HR. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Development (Cambridge, England). 134: 2991-9. PMID 17634190 DOI: 10.1242/Dev.009373 |
0.662 |
|
2007 |
Harrison MM, Lu X, Horvitz HR. LIN-61, one of two Caenorhabditis elegans malignant-brain-tumor-repeat-containing proteins, acts with the DRM and NuRD-like protein complexes in vulval development but not in certain other biological processes. Genetics. 176: 255-71. PMID 17409073 DOI: 10.1534/Genetics.106.069633 |
0.775 |
|
2007 |
Reddien PW, Andersen EC, Huang MC, Horvitz HR. DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans. Genetics. 175: 1719-33. PMID 17237514 DOI: 10.1534/Genetics.106.068148 |
0.814 |
|
2006 |
Harrison MM, Ceol CJ, Lu X, Horvitz HR. Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex. Proceedings of the National Academy of Sciences of the United States of America. 103: 16782-7. PMID 17075059 DOI: 10.1073/Pnas.0608461103 |
0.81 |
|
2006 |
Berdichevsky A, Viswanathan M, Horvitz HR, Guarente L. C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. Cell. 125: 1165-77. PMID 16777605 DOI: 10.1016/J.Cell.2006.04.036 |
0.451 |
|
2006 |
Andersen EC, Lu X, Horvitz HR. C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates. Development (Cambridge, England). 133: 2695-704. PMID 16774993 DOI: 10.1242/Dev.02444 |
0.781 |
|
2006 |
Su CW, Tharin S, Jin Y, Wightman B, Spector M, Meili D, Tsung N, Rhiner C, Bourikas D, Stoeckli E, Garriga G, Horvitz HR, Hengartner MO. The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans. Journal of Biology. 5: 9. PMID 16725058 DOI: 10.1186/Jbiol39 |
0.777 |
|
2006 |
Ceol CJ, Stegmeier F, Harrison MM, Horvitz HR. Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development. Genetics. 173: 709-26. PMID 16624904 DOI: 10.1534/Genetics.106.056465 |
0.815 |
|
2006 |
Shah PR, Ahmad-Annuar A, Ahmadi KR, Russ C, Sapp PC, Horvitz HR, Brown RH, Goldstein DB, Fisher EM. No association of DYNC1H1 with sporadic ALS in a case-control study of a northern European derived population: a tagging SNP approach. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 7: 46-56. PMID 16546759 DOI: 10.1080/14660820500397057 |
0.277 |
|
2006 |
Morita M, Al-Chalabi A, Andersen PM, Hosler B, Sapp P, Englund E, Mitchell JE, Habgood JJ, de Belleroche J, Xi J, Jongjaroenprasert W, Horvitz HR, Gunnarsson LG, Brown RH. A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology. 66: 839-44. PMID 16421333 DOI: 10.1212/01.wnl.0000200048.53766.b4 |
0.227 |
|
2005 |
Abbott AL, Alvarez-Saavedra E, Miska EA, Lau NC, Bartel DP, Horvitz HR, Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Developmental Cell. 9: 403-14. PMID 16139228 DOI: 10.1016/J.Devcel.2005.07.009 |
0.699 |
|
2005 |
Davison EM, Harrison MM, Walhout AJ, Vidal M, Horvitz HR. lin-8, which antagonizes Caenorhabditis elegans Ras-mediated vulval induction, encodes a novel nuclear protein that interacts with the LIN-35 Rb protein. Genetics. 171: 1017-31. PMID 16020796 DOI: 10.1534/Genetics.104.034173 |
0.718 |
|
2005 |
Frank CA, Hawkins NC, Guenther C, Horvitz HR, Garriga G. C. elegans HAM-1 positions the cleavage plane and regulates apoptosis in asymmetric neuroblast divisions. Developmental Biology. 284: 301-10. PMID 15979607 DOI: 10.1016/j.ydbio.2005.05.026 |
0.79 |
|
2005 |
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. MicroRNA expression profiles classify human cancers. Nature. 435: 834-8. PMID 15944708 DOI: 10.1038/Nature03702 |
0.327 |
|
2005 |
Wienholds E, Kloosterman WP, Miska E, Alvarez-Saavedra E, Berezikov E, de Bruijn E, Horvitz HR, Kauppinen S, Plasterk RH. MicroRNA expression in zebrafish embryonic development. Science (New York, N.Y.). 309: 310-1. PMID 15919954 DOI: 10.1126/Science.1114519 |
0.367 |
|
2005 |
Horvitz HR. Obituary: Stanley J. Korsmeyer (1950-2005). Nature. 435: 161. PMID 15889078 DOI: 10.1038/435161a |
0.296 |
|
2005 |
Menard C, Horvitz HR, Cannon S. Chimeric mutations in the M2 segment of the 5-hydroxytryptamine-gated chloride channel MOD-1 define a minimal determinant of anion/cation permeability. The Journal of Biological Chemistry. 280: 27502-7. PMID 15878844 DOI: 10.1074/Jbc.M501624200 |
0.351 |
|
2005 |
Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR. Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system. Neuron. 46: 247-60. PMID 15848803 DOI: 10.1016/j.neuron.2005.02.024 |
0.765 |
|
2004 |
Reddien PW, Horvitz HR. The engulfment process of programmed cell death in caenorhabditis elegans. Annual Review of Cell and Developmental Biology. 20: 193-221. PMID 15473839 DOI: 10.1146/Annurev.Cellbio.20.022003.114619 |
0.728 |
|
2004 |
Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR. Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biology. 5: R68. PMID 15345052 DOI: 10.1186/gb-2004-5-9-r68 |
0.469 |
|
2004 |
Jäger S, Schwartz HT, Horvitz HR, Conradt B. The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome. Proceedings of the National Academy of Sciences of the United States of America. 101: 12549-54. PMID 15306688 DOI: 10.1073/pnas.0405087101 |
0.721 |
|
2004 |
Ceol CJ, Horvitz HR. A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling. Developmental Cell. 6: 563-76. PMID 15068795 DOI: 10.1016/S1534-5807(04)00065-6 |
0.723 |
|
2004 |
Yuan J, Horvitz HR. A first insight into the molecular mechanisms of apoptosis. Cell. 116: S53-6, 1 p following. PMID 15055582 DOI: 10.1016/S0092-8674(04)00028-5 |
0.536 |
|
2003 |
Horvitz HR. Nobel lecture. Worms, life and death. Bioscience Reports. 23: 239-303. PMID 15074544 DOI: 10.1023/B:Bire.0000019187.19019.E6 |
0.341 |
|
2003 |
de la Cruz IP, Levin JZ, Cummins C, Anderson P, Horvitz HR. sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9133-45. PMID 14534247 DOI: 10.1523/Jneurosci.23-27-09133.2003 |
0.735 |
|
2003 |
Horvitz HR. Worms, life, and death (Nobel lecture). Chembiochem : a European Journal of Chemical Biology. 4: 697-711. PMID 12898619 DOI: 10.1002/cbic.200300614 |
0.35 |
|
2003 |
Sapp PC, Hosler BA, McKenna-Yasek D, Chin W, Gann A, Genise H, Gorenstein J, Huang M, Sailer W, Scheffler M, Valesky M, Haines JL, Pericak-Vance M, Siddique T, Horvitz HR, et al. Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis. American Journal of Human Genetics. 73: 397-403. PMID 12858291 DOI: 10.1086/377158 |
0.428 |
|
2003 |
Hwang HY, Olson SK, Esko JD, Horvitz HR. Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis. Nature. 423: 439-43. PMID 12761549 DOI: 10.1038/Nature01634 |
0.504 |
|
2003 |
Thomas JH, Ceol CJ, Schwartz HT, Horvitz HR. New genes that interact with lin-35 Rb to negatively regulate the let-60 ras pathway in Caenorhabditis elegans. Genetics. 164: 135-51. PMID 12750327 |
0.731 |
|
2003 |
Hwang HY, Olson SK, Brown JR, Esko JD, Horvitz HR. The Caenorhabditis elegans genes sqv-2 and sqv-6, which are required for vulval morphogenesis, encode glycosaminoglycan galactosyltransferase II and xylosyltransferase. The Journal of Biological Chemistry. 278: 11735-8. PMID 12584198 DOI: 10.1074/Jbc.C200518200 |
0.409 |
|
2002 |
Hwang HY, Horvitz HR. The Caenorhabditis elegans vulval morphogenesis gene sqv-4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated. Proceedings of the National Academy of Sciences of the United States of America. 99: 14224-9. PMID 12391315 DOI: 10.1073/pnas.172522499 |
0.503 |
|
2002 |
Hwang HY, Horvitz HR. The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 99: 14218-23. PMID 12391314 DOI: 10.1073/pnas.172522199 |
0.455 |
|
2002 |
Tzur YB, Hersh BM, Horvitz HR, Gruenbaum Y. Fate of the nuclear lamina during Caenorhabditis elegans apoptosis. Journal of Structural Biology. 137: 146-53. PMID 12064941 DOI: 10.1006/Jsbi.2002.4452 |
0.795 |
|
2002 |
Cameron S, Clark SG, McDermott JB, Aamodt E, Horvitz HR. PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans. Development (Cambridge, England). 129: 1763-74. PMID 11923211 |
0.736 |
|
2002 |
Hersh BM, Hartwieg E, Horvitz HR. The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types. Proceedings of the National Academy of Sciences of the United States of America. 99: 4355-60. PMID 11904372 DOI: 10.1073/Pnas.062065399 |
0.828 |
|
2001 |
Horvitz HR. Genetic Control of Programmed Cell Death in C. Elegans. Thescientificworldjournal. 1: 137. PMID 30147615 DOI: 10.1100/tsw.2001.235 |
0.454 |
|
2001 |
Starr DA, Hermann GJ, Malone CJ, Fixsen W, Priess JR, Horvitz HR, Han M. unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration. Development (Cambridge, England). 128: 5039-50. PMID 11748140 |
0.353 |
|
2001 |
Lundquist EA, Reddien PW, Hartwieg E, Horvitz HR, Bargmann CI. Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis. Development (Cambridge, England). 128: 4475-88. PMID 11714673 |
0.8 |
|
2001 |
Zhou Z, Caron E, Hartwieg E, Hall A, Horvitz HR. The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Developmental Cell. 1: 477-89. PMID 11703939 DOI: 10.1016/S1534-5807(01)00058-2 |
0.504 |
|
2001 |
Ranganathan R, Sawin ER, Trent C, Horvitz HR. Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent and -independent activities of fluoxetine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5871-84. PMID 11487610 DOI: 10.1523/Jneurosci.21-16-05871.2001 |
0.395 |
|
2001 |
Ceol CJ, Horvitz HR. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Molecular Cell. 7: 461-73. PMID 11463372 DOI: 10.1016/S1097-2765(01)00194-0 |
0.767 |
|
2001 |
Reddien PW, Cameron S, Horvitz HR. Phagocytosis promotes programmed cell death in C. elegans. Nature. 412: 198-202. PMID 11449278 DOI: 10.1038/35084096 |
0.745 |
|
2001 |
Berninsone P, Hwang HY, Zemtseva I, Horvitz HR, Hirschberg CB. SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP-N- acetylgalactosamine, and UDP-galactose. Proceedings of the National Academy of Sciences of the United States of America. 98: 3738-43. PMID 11259660 DOI: 10.1073/Pnas.061593098 |
0.397 |
|
2001 |
Zhou Z, Hartwieg E, Horvitz HR. CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans. Cell. 104: 43-56. PMID 11163239 DOI: 10.1016/S0092-8674(01)00190-8 |
0.508 |
|
2000 |
Ranganathan R, Cannon SC, Horvitz HR. MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans. Nature. 408: 470-5. PMID 11100728 DOI: 10.1038/35044083 |
0.344 |
|
2000 |
Hosler BA, Siddique T, Sapp PC, Sailor W, Huang MC, Hossain A, Daube JR, Nance M, Fan C, Kaplan J, Hung WY, McKenna-Yasek D, Haines JL, Pericak-Vance MA, Horvitz HR, et al. Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22. Jama. 284: 1664-9. PMID 11015796 DOI: 10.1001/Jama.284.13.1664 |
0.36 |
|
2000 |
Speliotes EK, Uren A, Vaux D, Horvitz HR. The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone. Molecular Cell. 6: 211-23. PMID 10983970 DOI: 10.1016/S1097-2765(00)00023-X |
0.405 |
|
2000 |
Beitel GJ, Lambie EJ, Horvitz HR. The C. elegans gene lin-9,which acts in an Rb-related pathway, is required for gonadal sheath cell development and encodes a novel protein. Gene. 254: 253-63. PMID 10974557 DOI: 10.1016/S0378-1119(00)00296-1 |
0.758 |
|
2000 |
Harris TW, Hartwieg E, Horvitz HR, Jorgensen EM. Mutations in synaptojanin disrupt synaptic vesicle recycling. The Journal of Cell Biology. 150: 589-600. PMID 10931870 DOI: 10.1083/Jcb.150.3.589 |
0.551 |
|
2000 |
Sawin ER, Ranganathan R, Horvitz HR. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron. 26: 619-31. PMID 10896158 DOI: 10.1016/S0896-6273(00)81199-X |
0.368 |
|
2000 |
Stanfield GM, Horvitz HR. The ced-8 gene controls the timing of programmed cell deaths in C. elegans. Molecular Cell. 5: 423-33. PMID 10882128 DOI: 10.1016/S1097-2765(00)80437-2 |
0.825 |
|
2000 |
Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Molecular Cell. 5: 659-69. PMID 10882102 DOI: 10.1016/S1097-2765(00)80245-2 |
0.804 |
|
2000 |
Wu YC, Stanfield GM, Horvitz HR. NUC-1, a caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis. Genes & Development. 14: 536-48. PMID 10716942 DOI: 10.1101/Gad.14.5.536 |
0.685 |
|
2000 |
Reddien PW, Horvitz HR. CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans. Nature Cell Biology. 2: 131-6. PMID 10707082 DOI: 10.1038/35004000 |
0.717 |
|
2000 |
Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature. 403: 901-6. PMID 10706289 DOI: 10.1038/35002607 |
0.805 |
|
2000 |
Chen F, Hersh BM, Conradt B, Zhou Z, Riemer D, Gruenbaum Y, Horvitz HR. Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death. Science (New York, N.Y.). 287: 1485-9. PMID 10688797 DOI: 10.1126/Science.287.5457.1485 |
0.813 |
|
2000 |
Lorson MA, Horvitz HR, van den Heuvel S. LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. The Journal of Cell Biology. 148: 73-86. PMID 10629219 DOI: 10.1083/jcb.148.1.73 |
0.462 |
|
1999 |
Shaham S, Reddien PW, Davies B, Horvitz HR. Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3. Genetics. 153: 1655-71. PMID 10581274 |
0.821 |
|
1999 |
Newman AP, Acton GZ, Hartwieg E, Horvitz HR, Sternberg PW. The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells. Development (Cambridge, England). 126: 5319-26. PMID 10556057 |
0.575 |
|
1999 |
Metzstein MM, Horvitz HR. The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein. Molecular Cell. 4: 309-19. PMID 10518212 DOI: 10.1016/S1097-2765(00)80333-0 |
0.536 |
|
1999 |
Conradt B, Horvitz HR. The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene. Cell. 98: 317-27. PMID 10458607 DOI: 10.1016/S0092-8674(00)81961-3 |
0.739 |
|
1999 |
Eastman C, Horvitz HR, Jin Y. Coordinated transcriptional regulation of the unc-25 glutamic acid decarboxylase and the unc-47 GABA vesicular transporter by the Caenorhabditis elegans UNC-30 homeodomain protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6225-34. PMID 10414952 DOI: 10.1523/Jneurosci.19-15-06225.1999 |
0.651 |
|
1999 |
Thomas JH, Horvitz HR. The C. elegans gene lin-36 acts cell autonomously in the lin-35 Rb pathway. Development (Cambridge, England). 126: 3449-59. PMID 10393123 |
0.432 |
|
1999 |
Malone CJ, Fixsen WD, Horvitz HR, Han M. UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development. Development (Cambridge, England). 126: 3171-81. PMID 10375507 |
0.399 |
|
1999 |
Horvitz HR. Genetic control of programmed cell death in the nematode Caenorhabditis elegans. Cancer Research. 59: 1701s-1706s. PMID 10197583 DOI: 10.1007/978-1-4757-9217-1_1 |
0.527 |
|
1999 |
Herman T, Horvitz HR. Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway. Proceedings of the National Academy of Sciences of the United States of America. 96: 974-9. PMID 9927678 DOI: 10.1073/Pnas.96.3.974 |
0.756 |
|
1999 |
Herman T, Hartwieg E, Horvitz HR. sqv mutants of Caenorhabditis elegans are defective in vulval epithelial invagination. Proceedings of the National Academy of Sciences of the United States of America. 96: 968-73. PMID 9927677 |
0.767 |
|
1999 |
Gumienny TL, Lambie E, Hartwieg E, Horvitz HR, Hengartner MO. Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. Development (Cambridge, England). 126: 1011-22. PMID 9927601 DOI: 10.5167/Uzh-1041 |
0.811 |
|
1999 |
Jin Y, Jorgensen E, Hartwieg E, Horvitz HR. The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 539-48. PMID 9880574 DOI: 10.1523/Jneurosci.19-02-00539.1999 |
0.687 |
|
1999 |
Lee RY, Sawin ER, Chalfie M, Horvitz HR, Avery L. EAT-4, a homolog of a mammalian sodium-dependent inorganic phosphate cotransporter, is necessary for glutamatergic neurotransmission in caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 159-67. PMID 9870947 DOI: 10.1523/Jneurosci.19-01-00159.1999 |
0.651 |
|
1998 |
Hosler BA, Sapp PC, Berger R, O'Neill G, Bejaoui K, Hamida MB, Hentati F, Chin W, McKenna-Yasek D, Haines JL, Patterson D, Horvitz HR, Brown RH, Day CB. Refined mapping and characterization of the recessive familial amyotrophic lateral sclerosis locus (ALS2) on chromosome 2q33. Neurogenetics. 2: 34-42. PMID 9933298 DOI: 10.1007/S100480050049 |
0.384 |
|
1998 |
Lu X, Horvitz HR. lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48. Cell. 95: 981-91. PMID 9875852 DOI: 10.1016/S0092-8674(00)81722-5 |
0.677 |
|
1998 |
Metzstein MM, Stanfield GM, Horvitz HR. Genetics of programmed cell death in C. elegans: past, present and future. Trends in Genetics : Tig. 14: 410-6. PMID 9820030 DOI: 10.1016/S0168-9525(98)01573-X |
0.825 |
|
1998 |
Gonzales-Rosales F, Walsh D, Burkons L, Burkons J, Horvitz HR. Chronic bleeding secondary to an unresectable duodenal adenocarcinoma controlled with sucralfate and famotidine. Palliative Medicine. 12: 205-6. PMID 9743840 DOI: 10.1191/026921698674325884 |
0.178 |
|
1998 |
Jacobs D, Beitel GJ, Clark SG, Horvitz HR, Kornfeld K. Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase. Genetics. 149: 1809-22. PMID 9691039 |
0.794 |
|
1998 |
Wu YC, Horvitz HR. The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters. Cell. 93: 951-60. PMID 9635425 DOI: 10.1016/S0092-8674(00)81201-5 |
0.734 |
|
1998 |
Conradt B, Horvitz HR. The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell. 93: 519-29. PMID 9604928 DOI: 10.1016/S0092-8674(00)81182-4 |
0.743 |
|
1998 |
Kokel M, Borland CZ, DeLong L, Horvitz HR, Stern MJ. clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans. Genes & Development. 12: 1425-37. PMID 9585503 |
0.364 |
|
1998 |
Aoki M, Lin CL, Rothstein JD, Geller BA, Hosler BA, Munsat TL, Horvitz HR, Brown RH. Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis. Annals of Neurology. 43: 645-53. PMID 9585360 DOI: 10.1002/Ana.410430514 |
0.446 |
|
1998 |
Wu YC, Horvitz HR. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature. 392: 501-4. PMID 9548255 DOI: 10.1038/33163 |
0.73 |
|
1998 |
Hodgkin J, Horvitz HR, Jasny BR, Kimble J. C. elegans: Sequence to biology Science. 282: 2011. DOI: 10.1126/Science.282.5396.2011 |
0.652 |
|
1997 |
Herman T, Horvitz HR. Mutations that perturb vulval invagination in C. elegans. Cold Spring Harbor Symposia On Quantitative Biology. 62: 353-9. PMID 9598369 |
0.74 |
|
1997 |
Tax FE, Thomas JH, Ferguson EL, Horvitz HR. Identification and characterization of genes that interact with lin-12 in Caenorhabditis elegans. Genetics. 147: 1675-95. PMID 9409830 |
0.626 |
|
1997 |
Xue D, Horvitz HR. Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor. Nature. 390: 305-8. PMID 9384385 DOI: 10.1038/36889 |
0.503 |
|
1997 |
Barkett M, Xue D, Horvitz HR, Gilmore TD. Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro. The Journal of Biological Chemistry. 272: 29419-22. PMID 9367996 DOI: 10.1074/Jbc.272.47.29419 |
0.407 |
|
1997 |
Nonet ML, Staunton JE, Kilgard MP, Fergestad T, Hartwieg E, Horvitz HR, Jorgensen EM, Meyer BJ. Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8061-73. PMID 9334382 DOI: 10.1523/Jneurosci.17-21-08061.1997 |
0.654 |
|
1997 |
Lee RY, Lobel L, Hengartner M, Horvitz HR, Avery L. Mutations in the alpha1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegans. The Embo Journal. 16: 6066-76. PMID 9321386 DOI: 10.1093/Emboj/16.20.6066 |
0.598 |
|
1997 |
Bloom L, Horvitz HR. The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation. Proceedings of the National Academy of Sciences of the United States of America. 94: 3414-9. PMID 9096408 DOI: 10.1073/pnas.94.7.3414 |
0.347 |
|
1997 |
Cudkowicz ME, McKenna-Yasek D, Sapp PE, Chin W, Geller B, Hayden DL, Schoenfeld DA, Hosler BA, Horvitz HR, Brown RH. Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis. Annals of Neurology. 41: 210-21. PMID 9029070 DOI: 10.1002/Ana.410410212 |
0.326 |
|
1997 |
Nonet ML, Staunton JE, Kilgard MP, Fergestad T, Hartwieg E, Horvitz HR, Jorgensen EM, Meyer BJ. Caenorhabditis elegans rab-3Mutant Synapses Exhibit Impaired Function and Are Partially Depleted of Vesicles The Journal of Neuroscience. 17: 8061-8073. DOI: 10.1523/JNEUROSCI.17-21-08061.1997 |
0.508 |
|
1997 |
Aoki M, Rothstein JD, Lin CG, Geller BA, Hosler BA, Munsat TL, Horvitz HR, Brown RH. Mutations of the glutamate transporter gene EAAT2 do not cause the abnormal EAAT2 transcripts in patients with amyotrophic lateral sclerosis Neuromuscular Disorders. 7: 475. DOI: 10.1016/S0960-8966(97)87358-0 |
0.413 |
|
1996 |
Hosler BA, Nicholson GA, Sapp PC, Chin W, Orrell RW, de Belleroche JS, Esteban J, Hayward LJ, Mckenna-Yasek D, Yeung L, Cherryson AK, Dench JE, Wilton SD, Laing NG, Horvitz HR, et al. Three novel mutations and two variants in the gene for Cu/Zn superoxide dismutase in familial amyotrophic lateral sclerosis. Neuromuscular Disorders : Nmd. 6: 361-6. PMID 8938700 DOI: 10.1016/0960-8966(96)00353-7 |
0.433 |
|
1996 |
Sawa H, Lobel L, Horvitz HR. The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein. Genes & Development. 10: 2189-97. PMID 8804313 |
0.44 |
|
1996 |
Labouesse M, Hartwieg E, Horvitz HR. The Caenorhabditis elegans LIN-26 protein is required to specify and/or maintain all non-neuronal ectodermal cell fates. Development (Cambridge, England). 122: 2579-88. PMID 8787733 |
0.443 |
|
1996 |
Basson M, Horvitz HR. The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger protein. Genes & Development. 10: 1953-65. PMID 8756352 |
0.451 |
|
1996 |
Shaham S, Horvitz HR. An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor. Cell. 86: 201-8. PMID 8706125 DOI: 10.1016/S0092-8674(00)80092-6 |
0.791 |
|
1996 |
Metzstein MM, Hengartner MO, Tsung N, Ellis RE, Horvitz HR. Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2. Nature. 382: 545-7. PMID 8700229 DOI: 10.1038/382545a0 |
0.739 |
|
1996 |
Barnes TM, Jin Y, Horvitz HR, Ruvkun G, Hekimi S. The Caenorhabditis elegans behavioral gene unc-24 encodes a novel bipartite protein similar to both erythrocyte band 7.2 (stomatin) and nonspecific lipid transfer protein. Journal of Neurochemistry. 67: 46-57. PMID 8667025 DOI: 10.1046/J.1471-4159.1996.67010046.X |
0.693 |
|
1996 |
Xue D, Shaham S, Horvitz HR. The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes & Development. 10: 1073-83. PMID 8654923 |
0.755 |
|
1996 |
Shaham S, Horvitz HR. Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities. Genes & Development. 10: 578-91. PMID 8598288 |
0.787 |
|
1996 |
Koelle MR, Horvitz HR. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell. 84: 115-25. PMID 8548815 DOI: 10.1016/S0092-8674(00)80998-8 |
0.733 |
|
1995 |
Beitel GJ, Tuck S, Greenwald I, Horvitz HR. The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes & Development. 9: 3149-62. PMID 8543158 DOI: 10.1101/Gad.9.24.3149 |
0.804 |
|
1995 |
Kornfeld K, Hom DB, Horvitz HR. The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell. 83: 903-13. PMID 8521514 DOI: 10.1016/0092-8674(95)90206-6 |
0.722 |
|
1995 |
Kornfeld K, Guan KL, Horvitz HR. The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. Genes & Development. 9: 756-68. PMID 7729691 DOI: 10.1101/Gad.9.6.756 |
0.712 |
|
1995 |
Bowling AC, Barkowski EE, McKenna-Yasek D, Sapp P, Horvitz HR, Beal MF, Brown RH. Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis. Journal of Neurochemistry. 64: 2366-9. PMID 7722523 DOI: 10.1046/J.1471-4159.1995.64052366.X |
0.376 |
|
1995 |
Xue D, Horvitz HR. Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein. Nature. 377: 248-51. PMID 7675111 DOI: 10.1038/377248a0 |
0.387 |
|
1995 |
Chisholm AD, Horvitz HR. Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3. Nature. 377: 52-5. PMID 7659159 DOI: 10.1038/377052A0 |
0.658 |
|
1995 |
DeVore DL, Horvitz HR, Stern MJ. An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites. Cell. 83: 611-20. PMID 7585964 DOI: 10.1016/0092-8674(95)90101-9 |
0.687 |
|
1995 |
Herman MA, Vassilieva LL, Horvitz HR, Shaw JE, Herman RK. The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously. Cell. 83: 101-10. PMID 7553861 DOI: 10.1016/0092-8674(95)90238-4 |
0.73 |
|
1995 |
Sapp PC, Rosen DR, Hosler BA, Esteban J, McKenna-Yasek D, O'Regan JP, Horvitz HR, Brown RH. Identification of three novel mutations in the gene for Cu/Zn superoxide dismutase in patients with familial amyotrophic lateral sclerosis. Neuromuscular Disorders : Nmd. 5: 353-7. PMID 7496169 DOI: 10.1016/0960-8966(95)00007-A |
0.451 |
|
1995 |
Jorgensen EM, Hartwieg E, Schuske K, Nonet ML, Jin Y, Horvitz HR. Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans. Nature. 378: 196-9. PMID 7477324 DOI: 10.1038/378196a0 |
0.661 |
|
1994 |
Lackner MR, Kornfeld K, Miller LM, Horvitz HR, Kim SK. A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans. Genes & Development. 8: 160-73. PMID 8299936 DOI: 10.1101/Gad.8.2.160 |
0.709 |
|
1994 |
Herman MA, Horvitz HR. The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions. Development (Cambridge, England). 120: 1035-47. PMID 8026318 |
0.66 |
|
1994 |
Jin Y, Hoskins R, Horvitz HR. Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein. Nature. 372: 780-3. PMID 7997265 DOI: 10.1038/372780a0 |
0.63 |
|
1994 |
Clark SG, Lu X, Horvitz HR. The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins. Genetics. 137: 987-97. PMID 7982579 |
0.771 |
|
1994 |
Gregor P, Gaston SM, Yang X, O'Regan JP, Rosen DR, Tanzi RE, Patterson D, Haines JL, Horvitz HR, Uhl GR. Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21. Human Genetics. 94: 565-70. PMID 7959697 DOI: 10.1007/Bf00211029 |
0.4 |
|
1994 |
Labouesse M, Sookhareea S, Horvitz HR. The Caenorhabditis elegans gene lin-26 is required to specify the fates of hypodermal cells and encodes a presumptive zinc-finger transcription factor. Development (Cambridge, England). 120: 2359-68. PMID 7956818 |
0.465 |
|
1994 |
Esteban J, Rosen DR, Bowling AC, Sapp P, McKenna-Yasek D, O'Regan JP, Beal MF, Horvitz HR, Brown RH. Identification of two novel mutations and a new polymorphism in the gene for Cu/Zn superoxide dismutase in patients with amyotrophic lateral sclerosis. Human Molecular Genetics. 3: 997-8. PMID 7951252 DOI: 10.1093/Hmg/3.6.997 |
0.394 |
|
1994 |
Hengartner MO, Horvitz HR. Programmed cell death in Caenorhabditis elegans. Current Opinion in Genetics & Development. 4: 581-6. PMID 7950327 DOI: 10.1016/0959-437X(94)90076-F |
0.67 |
|
1994 |
Rosen DR, Sapp P, O'Regan J, McKenna-Yasek D, Schlumpf KS, Haines JL, Gusella JF, Horvitz HR, Brown RH. Genetic linkage analysis of familial amyotrophic lateral sclerosis using human chromosome 21 microsatellite DNA markers. American Journal of Medical Genetics. 51: 61-9. PMID 7913294 DOI: 10.1002/Ajmg.1320510114 |
0.268 |
|
1994 |
Hengartner MO, Horvitz HR. Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2. Nature. 369: 318-20. PMID 7910376 DOI: 10.1038/369318a0 |
0.674 |
|
1994 |
Hengartner MO, Horvitz HR. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell. 76: 665-76. PMID 7907274 DOI: 10.1016/0092-8674(94)90506-1 |
0.684 |
|
1994 |
Hengartner MO, Horvitz HR. The ins and outs of programmed cell death during C. elegans development. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 243-6. PMID 7846120 DOI: 10.1098/rstb.1994.0100 |
0.673 |
|
1994 |
Horvitz HR, Shaham S, Hengartner MO. The genetics of programmed cell death in the nematode Caenorhabditis elegans. Cold Spring Harbor Symposia On Quantitative Biology. 59: 377-85. PMID 7587090 DOI: 10.1101/SQB.1994.059.01.042 |
0.78 |
|
1994 |
Rosen DR, Sapp P, McKenna-Yasek D, Horvitz HR, Brown RH. A molecular basis of familial ALS Clinical Chemistry. 40: 638-639. |
0.209 |
|
1993 |
Kaplan JM, Horvitz HR. A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 90: 2227-31. PMID 8460126 DOI: 10.1073/Pnas.90.6.2227 |
0.516 |
|
1993 |
Bargmann CI, Hartwieg E, Horvitz HR. Odorant-selective genes and neurons mediate olfaction in C. elegans. Cell. 74: 515-27. PMID 8348618 DOI: 10.1016/0092-8674(93)80053-H |
0.701 |
|
1993 |
McIntire SL, Jorgensen E, Kaplan J, Horvitz HR. The GABAergic nervous system of Caenorhabditis elegans. Nature. 364: 337-41. PMID 8332191 DOI: 10.1038/364337a0 |
0.775 |
|
1993 |
McIntire SL, Jorgensen E, Horvitz HR. Genes required for GABA function in Caenorhabditis elegans. Nature. 364: 334-7. PMID 8332190 DOI: 10.1038/364334A0 |
0.767 |
|
1993 |
Avery L, Bargmann CI, Horvitz HR. The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions. Genetics. 134: 455-64. PMID 8325482 |
0.714 |
|
1993 |
Garriga G, Desai C, Horvitz HR. Cell interactions control the direction of outgrowth, branching and fasciculation of the HSN axons of Caenorhabditis elegans. Development (Cambridge, England). 117: 1071-87. PMID 8325236 |
0.611 |
|
1993 |
Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell. 75: 641-52. PMID 8242740 DOI: 10.1016/0092-8674(93)90485-9 |
0.824 |
|
1993 |
Garriga G, Guenther C, Horvitz HR. Migrations of the Caenorhabditis elegans HSNs are regulated by egl-43, a gene encoding two zinc finger proteins. Genes & Development. 7: 2097-109. PMID 8224840 DOI: 10.1101/Gad.7.11.2097 |
0.694 |
|
1993 |
Levin JZ, Horvitz HR. Three new classes of mutations in the Caenorhabditis elegans muscle gene sup-9. Genetics. 135: 53-70. PMID 8224828 |
0.334 |
|
1993 |
Clark SG, Chisholm AD, Horvitz HR. Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39. Cell. 74: 43-55. PMID 8101475 DOI: 10.1016/0092-8674(93)90293-Y |
0.799 |
|
1992 |
McIntire SL, Garriga G, White J, Jacobson D, Horvitz HR. Genes necessary for directed axonal elongation or fasciculation in C. elegans. Neuron. 8: 307-22. PMID 1739461 DOI: 10.1016/0896-6273(92)90297-Q |
0.783 |
|
1992 |
Horvitz HR, Herskowitz I. Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell. 68: 237-55. PMID 1733500 DOI: 10.1016/0092-8674(92)90468-R |
0.474 |
|
1992 |
Hengartner MO, Ellis RE, Horvitz HR. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature. 356: 494-9. PMID 1560823 DOI: 10.1038/356494a0 |
0.646 |
|
1992 |
Clark SG, Stern MJ, Horvitz HR. C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature. 356: 340-4. PMID 1372395 DOI: 10.1038/356340A0 |
0.79 |
|
1992 |
Clark SG, Stern MJ, Horvitz HR. Genes involved in two Caenorhabditis elegans cell-signaling pathways. Cold Spring Harbor Symposia On Quantitative Biology. 57: 363-73. PMID 1339671 DOI: 10.1101/Sqb.1992.057.01.041 |
0.706 |
|
1992 |
Levin JZ, Horvitz HR. The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction. The Journal of Cell Biology. 117: 143-55. PMID 1313436 DOI: 10.1083/Jcb.117.1.143 |
0.626 |
|
1992 |
Rosen DR, Sapp PC, O'Regan J, Horvitz HR, Donaldson DH, Nussbaum C, Gusella JF, Haines JL, Pestka S, Jung V. Dinucleotide repeat polymorphisms (D21S223 and D21S224) at 21q22.1. Human Molecular Genetics. 1: 547. PMID 1307256 DOI: 10.1093/Hmg/1.7.547 |
0.179 |
|
1992 |
Donaldson DH, Rosen DR, O'Regan J, Sapp PC, Horvitz HR, Gusella JF, Haines JL, Pestka S, Jung V, Nusbaum C. Two independent dinucleotide repeat polymorphisms at the D21S235 locus (21q22.1). Human Molecular Genetics. 1: 651. PMID 1301176 DOI: 10.1093/Hmg/1.8.651 |
0.193 |
|
1992 |
Yuan J, Horvitz HR. The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death. Development (Cambridge, England). 116: 309-20. PMID 1286611 |
0.468 |
|
1991 |
Bargmann CI, Horvitz HR. Control of larval development by chemosensory neurons in Caenorhabditis elegans. Science (New York, N.Y.). 251: 1243-6. PMID 2006412 |
0.684 |
|
1991 |
Ellis RE, Jacobson DM, Horvitz HR. Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics. 129: 79-94. PMID 1936965 |
0.665 |
|
1991 |
Li PM, Reichert J, Freyd G, Horvitz HR, Walsh CT. The LIM region of a presumptive Caenorhabditis elegans transcription factor is an iron-sulfur- and zinc-containing metallodomain. Proceedings of the National Academy of Sciences of the United States of America. 88: 9210-3. PMID 1924383 DOI: 10.1073/Pnas.88.20.9210 |
0.288 |
|
1991 |
Brown RH, Horvitz HR, Rouleau GA, McKenna-Yasek D, Beard C, Sapp P, Haines JL, Gusella JF, Figlewicz DA. Gene linkage in familial amyotrophic lateral sclerosis: a progress report. Advances in Neurology. 56: 215-26. PMID 1853758 |
0.3 |
|
1991 |
Yuan JY, Finney M, Tsung N, Horvitz HR. Tc4, a Caenorhabditis elegans transposable element with an unusual fold-back structure. Proceedings of the National Academy of Sciences of the United States of America. 88: 3334-8. PMID 1849651 DOI: 10.1073/Pnas.88.8.3334 |
0.487 |
|
1991 |
Stern MJ, Horvitz HR. A normally attractive cell interaction is repulsive in two C. elegans mesodermal cell migration mutants. Development (Cambridge, England). 113: 797-803. PMID 1821851 |
0.384 |
|
1991 |
Ellis RE, Yuan JY, Horvitz HR. Mechanisms and functions of cell death. Annual Review of Cell Biology. 7: 663-98. PMID 1809356 DOI: 10.1146/annurev.cb.07.110191.003311 |
0.597 |
|
1991 |
Ellis RE, Horvitz HR. Two C. elegans genes control the programmed deaths of specific cells in the pharynx. Development (Cambridge, England). 112: 591-603. PMID 1794327 |
0.481 |
|
1991 |
Sternberg PW, Horvitz HR. Signal transduction during C. elegans vulval induction. Trends in Genetics : Tig. 7: 366-71. PMID 1668188 DOI: 10.1016/0168-9525(91)90257-Q |
0.555 |
|
1991 |
Bargmann CI, Horvitz HR. Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans. Neuron. 7: 729-42. PMID 1660283 DOI: 10.1016/0896-6273(91)90276-6 |
0.704 |
|
1991 |
Horvitz HR, Sternberg PW. Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva. Nature. 351: 535-41. PMID 1646401 DOI: 10.1038/351535a0 |
0.565 |
|
1990 |
Thomas JH, Stern MJ, Horvitz HR. Cell interactions coordinate the development of the C. elegans egg-laying system. Cell. 62: 1041-52. PMID 2401010 DOI: 10.1016/0092-8674(90)90382-O |
0.658 |
|
1990 |
Ruvkun G, Gilbert W, Horvitz HR. Detection of mutations and DNA polymorphisms using whole genome Southern Cross hybridization. Nucleic Acids Research. 18: 809-15. PMID 2315039 DOI: 10.1093/Nar/18.4.809 |
0.751 |
|
1990 |
Yuan JY, Horvitz HR. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Developmental Biology. 138: 33-41. PMID 2307287 DOI: 10.1016/0012-1606(90)90174-H |
0.67 |
|
1990 |
Horvitz HR, Sulston JE. "Joy of the worm". Genetics. 126: 287-92. PMID 2245910 |
0.217 |
|
1990 |
Avery L, Horvitz HR. Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. The Journal of Experimental Zoology. 253: 263-70. PMID 2181052 DOI: 10.1002/jez.1402530305 |
0.226 |
|
1990 |
Kim SK, Horvitz HR. The Caenorhabditis elegans gene lin-10 is broadly expressed while required specifically for the determination of vulval cell fates. Genes & Development. 4: 357-71. PMID 2159938 |
0.493 |
|
1990 |
Bargmann CI, Thomas JH, Horvitz HR. Chemosensory cell function in the behavior and development of Caenorhabditis elegans. Cold Spring Harbor Symposia On Quantitative Biology. 55: 529-38. PMID 2132836 |
0.685 |
|
1990 |
Beitel GJ, Clark SG, Horvitz HR. Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction. Nature. 348: 503-9. PMID 2123303 DOI: 10.1038/348503A0 |
0.812 |
|
1990 |
Freyd G, Kim SK, Horvitz HR. Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11. Nature. 344: 876-9. PMID 1970421 DOI: 10.1038/344876a0 |
0.372 |
|
1990 |
HORVITZ H. Genetic control of cell death in the nematode Cell Biology International Reports. 14: 17. DOI: 10.1016/0309-1651(90)90179-3 |
0.341 |
|
1989 |
Horvitz HR, Clegg MT, Howe MM, Lindquist SL, Rothstein RJ. Genetics society of america program and abstracts. Genetics. 122: s1-s48. PMID 17246502 |
0.235 |
|
1989 |
Ferguson EL, Horvitz HR. The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways. Genetics. 123: 109-21. PMID 2806880 |
0.636 |
|
1989 |
Desai C, Horvitz HR. Caenorhabditis elegans mutants defective in the functioning of the motor neurons responsible for egg laying. Genetics. 121: 703-21. PMID 2721931 |
0.434 |
|
1989 |
Avery L, Horvitz HR. Pharyngeal pumping continues after laser killing of the pharyngeal nervous system of C. elegans. Neuron. 3: 473-85. PMID 2642006 |
0.306 |
|
1989 |
Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR. Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14. Genetics. 121: 501-16. PMID 2565854 |
0.801 |
|
1989 |
Sternberg PW, Horvitz HR. The combined action of two intercellular signaling pathways specifies three cell fates during vulval induction in C. elegans. Cell. 58: 679-93. PMID 2548732 DOI: 10.1016/0092-8674(89)90103-7 |
0.592 |
|
1989 |
Ferguson EL, Horvitz HR. The multivulva phenotype of certain C. elegans mutants results from defects in two functionally redundant pathways Trends in Genetics. 5: 363. |
0.595 |
|
1988 |
Trent C, Wood WB, Horvitz HR. A novel dominant transformer allele of the sex-determining gene her-1 of Caenorhabditis elegans. Genetics. 120: 145-57. PMID 3220248 |
0.358 |
|
1988 |
Desai C, Garriga G, McIntire SL, Horvitz HR. A genetic pathway for the development of the Caenorhabditis elegans HSN motor neurons. Nature. 336: 638-46. PMID 3200316 DOI: 10.1038/336638A0 |
0.817 |
|
1988 |
Sternberg PW, Horvitz HR. lin-17 mutations of Caenorhabditis elegans disrupt certain asymmetric cell divisions. Developmental Biology. 130: 67-73. PMID 3181641 DOI: 10.1016/0012-1606(88)90414-9 |
0.603 |
|
1988 |
Horvitz HR. Genetic control of Caenorhabditis elegans cell lineage. Harvey Lectures. 84: 65-77. PMID 3079281 |
0.321 |
|
1988 |
Finney M, Ruvkun G, Horvitz HR. The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors. Cell. 55: 757-69. PMID 2903797 DOI: 10.1016/0092-8674(88)90132-8 |
0.743 |
|
1988 |
Sulston J, Horvitz HR, Kimble J. APPENDIX 3 Cell Lineage Cold Spring Harbor Monograph Archive. 17: 457-489. DOI: 10.1101/087969307.17.457 |
0.416 |
|
1988 |
Horvitz HR. 6 Genetics of Cell Lineage Cold Spring Harbor Monograph Archive. 17: 157-190. DOI: 10.1101/087969307.17.157 |
0.499 |
|
1987 |
Avery L, Horvitz HR. A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant. Cell. 51: 1071-8. PMID 3690660 DOI: 10.1016/0092-8674(87)90593-9 |
0.515 |
|
1987 |
Ambros V, Horvitz HR. The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events. Genes & Development. 1: 398-414. PMID 3678829 DOI: 10.1101/Gad.1.4.398 |
0.755 |
|
1987 |
Ferguson EL, Sternberg PW, Horvitz HR. A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans. Nature. 326: 259-67. PMID 2881214 DOI: 10.1038/326259a0 |
0.743 |
|
1986 |
Ellis HM, Horvitz HR. Genetic control of programmed cell death in the nematode C. elegans. Cell. 44: 817-29. PMID 3955651 DOI: 10.1016/0092-8674(86)90004-8 |
0.47 |
|
1986 |
Sternberg PW, Horvitz HR. Pattern formation during vulval development in C. elegans. Cell. 44: 761-72. PMID 3753901 DOI: 10.1016/0092-8674(86)90842-1 |
0.602 |
|
1986 |
Park EC, Horvitz HR. C. elegans unc-105 mutations affect muscle and are suppressed by other mutations that affect muscle. Genetics. 113: 853-67. PMID 3744029 |
0.333 |
|
1986 |
Park EC, Horvitz HR. Mutations with dominant effects on the behavior and morphology of the nematode Caenorhabditis elegans. Genetics. 113: 821-52. PMID 3744028 |
0.41 |
|
1986 |
Greenwald I, Horvitz HR. A visible allele of the muscle gene sup-10X of C. elegans. Genetics. 113: 63-72. PMID 3710144 |
0.299 |
|
1985 |
Ferguson EL, Horvitz HR. Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans. Genetics. 110: 17-72. PMID 3996896 |
0.646 |
|
1984 |
Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science (New York, N.Y.). 226: 409-16. PMID 6494891 DOI: 10.1126/Science.6494891 |
0.764 |
|
1984 |
Sternberg PW, Horvitz HR. The genetic control of cell lineage during nematode development. Annual Review of Genetics. 18: 489-524. PMID 6397125 DOI: 10.1146/annurev.ge.18.120184.002421 |
0.544 |
|
1983 |
Trent C, Tsuing N, Horvitz HR. Egg-laying defective mutants of the nematode Caenorhabditis elegans. Genetics. 104: 619-47. PMID 11813735 |
0.388 |
|
1983 |
Greenwald IS, Sternberg PW, Horvitz HR. The lin-12 locus specifies cell fates in Caenorhabditis elegans. Cell. 34: 435-44. PMID 6616618 DOI: 10.1016/0092-8674(83)90377-X |
0.755 |
|
1983 |
Horvitz HR, Sternberg PW, Greenwald IS, Fixsen W, Ellis HM. Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans. Cold Spring Harbor Symposia On Quantitative Biology. 48: 453-63. PMID 6586368 DOI: 10.1101/Sqb.1983.048.01.050 |
0.757 |
|
1982 |
Horvitz HR, Sternberg PW. Nematode postembryonic cell lineages. Journal of Nematology. 14: 240-8. PMID 19295705 |
0.548 |
|
1982 |
Greenwald IS, Horvitz HR. Dominant suppressors of a muscle mutant define an essential gene of Caenorhabditis elegans. Genetics. 101: 211-25. PMID 7173602 |
0.36 |
|
1982 |
Sternberg PW, Horvitz HR. Postembryonic nongonadal cell lineages of the nematode Panagrellus redivivus: description and comparison with those of Caenorhabditis elegans. Developmental Biology. 93: 181-205. PMID 7128930 DOI: 10.1016/0012-1606(82)90251-2 |
0.592 |
|
1982 |
White JG, Horvitz HR, Sulston JE. Neurone differentiation in cell lineage mutants of Caenorhabditis elegans. Nature. 297: 584-7. PMID 7088142 DOI: 10.1038/297584A0 |
0.533 |
|
1982 |
Horvitz HR, Chalfie M, Trent C, Sulston JE, Evans PD. Serotonin and octopamine in the nematode Caenorhabditis elegans. Science (New York, N.Y.). 216: 1012-4. PMID 6805073 DOI: 10.1126/Science.6805073 |
0.568 |
|
1981 |
Sternberg PW, Horvitz HR. Gonadal cell lineages of the nematode Panagrellus redivivus and implications for evolution by the modification of cell lineage. Developmental Biology. 88: 147-66. PMID 7286441 DOI: 10.1016/0012-1606(81)90226-8 |
0.599 |
|
1981 |
Chalfie M, Horvitz HR, Sulston JE. Mutations that lead to reiterations in the cell lineages of C. elegans. Cell. 24: 59-69. PMID 7237544 DOI: 10.1016/0092-8674(81)90501-8 |
0.689 |
|
1981 |
Sulston JE, Horvitz HR. Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans. Developmental Biology. 82: 41-55. PMID 7014288 DOI: 10.1016/0012-1606(81)90427-9 |
0.536 |
|
1980 |
Horvitz HR, Sulston JE. Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans. Genetics. 96: 435-54. PMID 7262539 |
0.425 |
|
1980 |
Greenwald IS, Horvitz HR. unc-93(e1500): A behavioral mutant of Caenorhabditis elegans that defines a gene with a wild-type null phenotype. Genetics. 96: 147-64. PMID 6894129 |
0.37 |
|
1979 |
Hodgkin J, Horvitz HR, Brenner S. Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS. Genetics. 91: 67-94. PMID 17248881 |
0.499 |
|
1979 |
Horvitz HR, Brenner S, Hodgkin J, Herman RK. A uniform genetic nomenclature for the nematode Caenorhabditis elegans. Molecular & General Genetics : Mgg. 175: 129-33. PMID 292825 DOI: 10.1007/Bf00425528 |
0.707 |
|
1977 |
Sulston JE, Horvitz HR. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Developmental Biology. 56: 110-56. PMID 838129 DOI: 10.1016/0012-1606(77)90158-0 |
0.374 |
|
1975 |
Horvitz HR. Studies of mutations in T4 control genes 33 and 55. Genetics. 79: 349-60. PMID 1126625 |
0.371 |
|
1974 |
Horvitz HR. Bacteriophage T4 mutants deficient in alteration and modification of the Escherichia coli RNA polymerase. Journal of Molecular Biology. 90: 739-50. PMID 4615179 DOI: 10.1016/0022-2836(74)90537-3 |
0.24 |
|
1974 |
Horvitz HR. Control by bacteriophage T4 of two sequential phosphorylations of the alpha subunit of Escherichia coli RNA polymerase. Journal of Molecular Biology. 90: 727-38. PMID 4615178 DOI: 10.1016/0022-2836(74)90536-1 |
0.204 |
|
1973 |
Horvitz HR. Polypeptide bound to the host RNA polymerase is specified by T4 control gene 33. Nature: New Biology. 244: 137-40. PMID 4579464 DOI: 10.1038/Newbio244137A0 |
0.387 |
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