Ruben G. Vidal, PhD - Publications

Affiliations: 
pathology and Laboratory Medicine Indiana University, Bloomington, Bloomington, IN, United States 

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Year Citation  Score
2024 Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R. Cryo-EM structures of amyloid-β and tau filaments in Down syndrome. Nature Structural & Molecular Biology. PMID 38553642 DOI: 10.1038/s41594-024-01252-3  0.316
2024 Klingstedt T, Lantz L, Shirani H, Ge J, Hanrieder J, Vidal R, Ghetti B, Nilsson KPR. Thiophene-Based Ligands for Specific Assignment of Distinct Aβ Pathologies in Alzheimer's Disease. Acs Chemical Neuroscience. 15: 1581-1595. PMID 38523263 DOI: 10.1021/acschemneuro.4c00021  0.319
2023 Björk L, Shirani H, Todarwal Y, Linares M, Vidal R, Ghetti B, Norman P, Klingstedt T, Nilsson KPR. Distinct Heterocyclic Moieties Govern the Selectivity of Thiophene-Vinylene-Based Ligands Towards Aβ or Tau Pathology in Alzheime's Disease. European Journal of Organic Chemistry. 26. PMID 38585413 DOI: 10.1002/ejoc.202300583  0.32
2023 Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B. TAF15 amyloid filaments in frontotemporal lobar degeneration. Nature. PMID 38057661 DOI: 10.1038/s41586-023-06801-2  0.332
2022 Fernandez A, Gomez MT, Vidal R. Lack of ApoE inhibits ADan amyloidosis in a mouse model of Familial Danish Dementia. The Journal of Biological Chemistry. 102751. PMID 36436561 DOI: 10.1016/j.jbc.2022.102751  0.345
2022 Hallinan GI, Ozcan KA, Hoq MR, Cracco L, Vago FS, Bharath SR, Li D, Jacobsen M, Doud EH, Mosley AL, Fernandez A, Garringer HJ, Jiang W, Ghetti B, Vidal R. Cryo-EM structures of prion protein filaments from Gerstmann-Sträussler-Scheinker disease. Acta Neuropathologica. PMID 35819518 DOI: 10.1007/s00401-022-02461-0  0.309
2022 Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, et al. Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature. PMID 35344985 DOI: 10.1038/s41586-022-04650-z  0.36
2021 Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, et al. Structure-based classification of tauopathies. Nature. PMID 34588692 DOI: 10.1038/s41586-021-03911-7  0.314
2021 Hallinan GI, Hoq MR, Ghosh M, Vago FS, Fernandez A, Garringer HJ, Vidal R, Jiang W, Ghetti B. Structure of Tau filaments in Prion protein amyloidoses. Acta Neuropathologica. PMID 34128081 DOI: 10.1007/s00401-021-02336-w  0.369
2021 Klingstedt T, Shirani H, Ghetti B, Vidal R, Nilsson P. Thiophene-Based Optical Ligands That Selectively Detect Aβ Pathology in Alzheimer's Disease. Chembiochem : a European Journal of Chemical Biology. PMID 34101954 DOI: 10.1002/cbic.202100199  0.303
2020 Cisternas P, Taylor X, Perkins A, Maldonado O, Allman E, Cordova R, Marambio Y, Munoz B, Pennington T, Xiang S, Zhang J, Vidal R, Atwood B, Lasagna-Reeves CA. Vascular amyloid accumulation alters the gabaergic synapse and induces hyperactivity in a model of cerebral amyloid angiopathy. Aging Cell. e13233. PMID 32914559 DOI: 10.1111/Acel.13233  0.448
2020 Taylor X, Cisternas P, You Y, You Y, Xiang S, Marambio Y, Zhang J, Vidal R, Lasagna-Reeves CA. A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy. Journal of Neuroinflammation. 17: 223. PMID 32711525 DOI: 10.1186/S12974-020-01900-7  0.462
2020 Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Novel tau filament fold in corticobasal degeneration. Nature. PMID 32050258 DOI: 10.1038/S41586-020-2043-0  0.326
2020 Suryadevara V, Krehbiel CJ, Vidal R, Willis MS. A Striking Bone Phenotype in the Familial Danish Dementia (FDD) Tg+ Mouse The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06596  0.302
2019 Muhoberac BB, Vidal R. Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration Frontiers in Neuroscience. 13: 1195. PMID 31920471 DOI: 10.3389/Fnins.2019.01195  0.337
2019 Falcon B, Zivanov J, Zhang W, Murzin AG, Garringer HJ, Vidal R, Crowther RA, Newell KL, Ghetti B, Goedert M, Scheres SHW. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature. PMID 30894745 DOI: 10.1038/S41586-019-1026-5  0.428
2019 You Y, Perkins A, Cisternas P, Muñoz B, Taylor X, You Y, Garringer HJ, Oblak AL, Atwood BK, Vidal R, Lasagna-Reeves CA. Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy. Acta Neuropathologica Communications. 7: 26. PMID 30808415 DOI: 10.1186/S40478-019-0680-Z  0.458
2019 You Y, Perkins A, Cisternas P, Munoz B, Taylor X, You Y, Oblak AL, Atwood B, Vidal R, Reeves CAL. P4-131: Tau As A Mediator Of Neurotoxicity Associated To Cerebral Amyloid Angiopathy Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3792  0.39
2018 Falcon B, Zhang W, Schweighauser M, Murzin AG, Vidal R, Garringer HJ, Ghetti B, Scheres SHW, Goedert M. Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta Neuropathologica. PMID 30276465 DOI: 10.1007/S00401-018-1914-Z  0.409
2018 Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature. PMID 30158706 DOI: 10.1038/S41586-018-0454-Y  0.399
2018 Pappolla MA, Matsubara E, Vidal R, Pacheco-Quinto J, Poeggeler B, Zagorski M, Sambamurti K. Melatonin treatment enhances Aβ lymphatic clearance in a transgenic mouse model of amyloidosis. Current Alzheimer Research. PMID 29637859 DOI: 10.2174/1567205015666180411092551  0.424
2016 Garringer HJ, Sammeta N, Oblak A, Ghetti B, Vidal R. Amyloid and intracellular accumulation of BRI2. Neurobiology of Aging. 52: 90-97. PMID 28131015 DOI: 10.1016/J.Neurobiolaging.2016.12.018  0.49
2016 Garringer HJ, Irimia JM, Li W, Goodwin CB, Richine B, Acton A, Chan RJ, Peacock M, Muhoberac BB, Ghetti B, Vidal R. Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy. Plos One. 11: e0161341. PMID 27574973 DOI: 10.1371/Journal.Pone.0161341  0.331
2016 Ghetti B, Dlouhy SR, Dupree B, Epperson F, Murrell JR, Oblak AL, Piccardo P, Richardson RM, Spina S, Takao M, Vidal R, Yamaguchi K, Young K. Contribution Of The Neuropathology Laboratory At Indiana University To The Deciphering Of Dominantly Inherited Dementias: 1976-2016 Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1553  0.336
2015 Levites Y, O'Nuallain B, Puligedda RD, Ondrejcak T, Adekar SP, Chen C, Cruz PE, Rosario AM, Macy S, Mably AJ, Walsh DM, Vidal R, Solomon A, Brown D, Rowan MJ, et al. A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6265-76. PMID 25904780 DOI: 10.1523/Jneurosci.5109-14.2015  0.447
2015 Li W, Garringer HJ, Goodwin CB, Richine B, Acton A, VanDuyn N, Muhoberac BB, Irimia-Dominguez J, Chan RJ, Peacock M, Nass R, Ghetti B, Vidal R. Systemic and cerebral iron homeostasis in ferritin knock-out mice. Plos One. 10: e0117435. PMID 25629408 DOI: 10.1371/Journal.Pone.0117435  0.313
2014 Pappolla M, Sambamurti K, Vidal R, Pacheco-Quinto J, Poeggeler B, Matsubara E. Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice. Neurobiology of Disease. 71: 215-9. PMID 25102344 DOI: 10.1016/J.Nbd.2014.07.012  0.361
2014 Nishida K, Garringer HJ, Futamura N, Funakawa I, Jinnai K, Vidal R, Takao M. A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation. Journal of the Neurological Sciences. 342: 173-7. PMID 24825732 DOI: 10.1016/J.Jns.2014.03.060  0.378
2014 Marcora MS, Fernández-Gamba AC, Avendaño LA, Rotondaro C, Podhajcer OL, Vidal R, Morelli L, Ceriani MF, Castaño EM. Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia. Molecular Neurodegeneration. 9: 5. PMID 24405716 DOI: 10.1186/1750-1326-9-5  0.434
2013 Muhoberac BB, Vidal R. Abnormal iron homeostasis and neurodegeneration. Frontiers in Aging Neuroscience. 5: 32-32. PMID 23908629 DOI: 10.3389/Fnagi.2013.00032  0.359
2013 Garringer HJ, Murrell J, Sammeta N, Gnezda A, Ghetti B, Vidal R. Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice. Plos One. 8: e56426. PMID 23418567 DOI: 10.1371/Journal.Pone.0056426  0.421
2012 Vidal R, Ghetti B. Generation of a novel murine model of Aβ deposition based on the expression of human wild-type amyloid precursor protein gene. Prion. 6: 346-9. PMID 22874668 DOI: 10.4161/Pri.21023  0.468
2012 Vidal R, Sammeta N, Garringer HJ, Sambamurti K, Miravalle L, Lamb BT, Ghetti B. The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2899-910. PMID 22459153 DOI: 10.1096/Fj.12-205542  0.467
2012 Baraibar MA, Barbeito AG, Muhoberac BB, Vidal R. A mutant light chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage Free Radical Biology and Medicine. 52: 1692-1697. PMID 22348978 DOI: 10.1016/J.Freeradbiomed.2012.02.015  0.333
2012 Ghetti B, Vidal R, Sammeta N, Garringer H, Sambamurti K, Miravalle L, Lamb B. The Psen1-L166P knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice Alzheimers & Dementia. 8: 86. DOI: 10.1016/J.Jalz.2012.05.209  0.418
2012 Ghetti B, Murrell J, Koeppe R, Gilman S, Fink J, Miravalle L, Albin R, Vidal R, Foster N. Follow-up of the first American report of familial Alzheimer's disease Alzheimers & Dementia. 8: 665. DOI: 10.1016/J.Jalz.2012.05.1793  0.352
2012 Ghetti B, Murrell J, Boyer P, Piccardo P, Vidal R, Hargrave K, Scott K, Silber M, Filley C, DeMasters B, Iyriboz T, Towfighi J. P4-090: Early-onset Alzheimer's disease associated with PSEN1 L166P mutation: An atypical clinical phenotype Alzheimer's & Dementia. 8: P664-P665. DOI: 10.1016/J.Jalz.2012.05.1792  0.359
2011 Vidal R, Ghetti B. Characterization of amyloid deposits in neurodegenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 793: 241-58. PMID 21913105 DOI: 10.1007/978-1-61779-328-8_16  0.473
2011 Muhoberac BB, Baraibar MA, Vidal R. Iron loading-induced aggregation and reduction of iron incorporation in heteropolymeric ferritin containing a mutant light chain that causes neurodegeneration. Biochimica Et Biophysica Acta. 1812: 544-548. PMID 21029774 DOI: 10.1016/J.Bbadis.2010.10.010  0.331
2010 Barbeito AG, Levade T, Delisle MB, Ghetti B, Vidal R. Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy. Molecular Neurodegeneration. 5: 50. PMID 21067605 DOI: 10.1186/1750-1326-5-50  0.35
2010 Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L. Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14915-24. PMID 21048150 DOI: 10.1523/Jneurosci.3917-10.2010  0.404
2010 Deng X, Vidal R, Englander EW. Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy Neuroscience Letters. 479: 44-48. PMID 20478358 DOI: 10.1016/J.Neulet.2010.05.025  0.327
2010 Baraibar MA, Muhoberac BB, Garringer HJ, Hurley TD, Vidal R. Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration. The Journal of Biological Chemistry. 285: 1950-6. PMID 19923220 DOI: 10.1074/Jbc.M109.042986  0.34
2010 Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R. Modeling familial British and Danish dementia. Brain Structure & Function. 214: 235-44. PMID 19779737 DOI: 10.1007/S00429-009-0221-9  0.461
2010 Vidal R. Mouse models of British and Danish dementia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.191  0.308
2009 Giliberto L, Matsuda S, Vidal R, D'Adamio L. Generation and initial characterization of FDD knock in mice. Plos One. 4: e7900. PMID 19924302 DOI: 10.1371/Journal.Pone.0007900  0.48
2009 Barbeito AG, Garringer HJ, Baraibar MA, Gao X, Arredondo M, Núñez MT, Smith MA, Ghetti B, Vidal R. Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene. Journal of Neurochemistry. 109: 1067-78. PMID 19519778 DOI: 10.1111/J.1471-4159.2009.06028.X  0.371
2009 Ory-Magne F, Brefel-Courbon C, Payoux P, Debruxelles S, Sibon I, Goizet C, Labauge P, Menegon P, Uro-Coste E, Ghetti B, Delisle MB, Vidal R, Rascol O. Clinical phenotype and neuroimaging findings in a French family with hereditary ferritinopathy (FTL498-499InsTC). Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1676-83. PMID 19514068 DOI: 10.1002/Mds.22669  0.367
2009 Vidal R, Barbeito AG, Miravalle L, Ghetti B. Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2. Brain Pathology (Zurich, Switzerland). 19: 58-68. PMID 18410407 DOI: 10.1111/J.1750-3639.2008.00164.X  0.498
2008 Maarouf CL, Daugs ID, Spina S, Vidal R, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Walker DG, Castaño EM, Beach TG, Ghetti B, Roher AE. Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations. Molecular Neurodegeneration. 3: 20. PMID 19021905 DOI: 10.1186/1750-1326-3-20  0.471
2008 Baraibar MA, Barbeito AG, Muhoberac BB, Vidal R. Iron-mediated Aggregation and a Localized Structural Change Characterize Ferritin from a Mutant Light Chain Polypeptide That Causes Neurodegeneration Journal of Biological Chemistry. 283: 31679-31689. PMID 18755684 DOI: 10.1074/Jbc.M805532200  0.333
2008 Van Vickle GD, Esh CL, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Beach TG, Newel AJ, Lopera F, Ghetti B, Vidal R, Castaño EM, Roher AE. Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 14: 184-94. PMID 18317569 DOI: 10.2119/2007-00094.Vanvickle  0.45
2008 Vidal R, Miravalle L, Gao X, Barbeito AG, Baraibar MA, Hekmatyar SK, Widel M, Bansal N, Delisle MB, Ghetti B. Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 60-7. PMID 18171923 DOI: 10.1523/Jneurosci.3962-07.2008  0.386
2008 Vidal R, Miravalle L, Barbeito AG, Baraibar MA, Bansal N, Smith MA, Delisle MB, Ghetti B. P1-105: Neurodegeneration and iron overload in transgenic mice expressing a mutant form of the ferritin light polypeptide gene Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.692  0.329
2008 Vidal R, Barbeito AG, Miravalle L, Ghetti B. O3-01-04: Vascular amyloid deposition and related pathology in a transgenic mouse model of familial Danish dementia Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.408  0.401
2008 Spina S, Laar ADV, Murrell JR, Courten-Myers Gd, Hamilton RL, Vidal R, Farlow MR, Quinlan J, DeKosky ST, Ghetti B. O2-05-03: Inclusion body myopathy with paget disease of the bone and frontotemporal dementia: New families, a novel mutation, and a new clinical presentation Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.342  0.327
2008 Ghetti B, Hake AM, Murrell JR, Epperson F, Farlow MR, Vidal R, Spina S. P3-221: Familial Alzheimer's disease associated with the V717L amyloid precursor protein gene mutation: Neuropathological characterization Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1788  0.464
2007 Spina S, Murrell JR, Huey ED, Wassermann EM, Pietrini P, Baraibar MA, Barbeito AG, Troncoso JC, Vidal R, Ghetti B, Grafman J. Clinicopathologic features of frontotemporal dementia with progranulin sequence variation. Neurology. 68: 820-7. PMID 17202431 DOI: 10.1212/01.Wnl.0000254460.31273.2D  0.31
2005 Miravalle L, Calero M, Takao M, Roher AE, Ghetti B, Vidal R. Amino-terminally truncated Abeta peptide species are the main component of cotton wool plaques. Biochemistry. 44: 10810-21. PMID 16086583 DOI: 10.1021/Bi0508237  0.429
2004 Vidal R, Delisle MB, Ghetti B. Neurodegeneration caused by proteins with an aberrant carboxyl-terminus. Journal of Neuropathology and Experimental Neurology. 63: 787-800. PMID 15330334 DOI: 10.1093/Jnen/63.8.787  0.377
2004 Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Early-onset dementia with Lewy bodies. Brain Pathology (Zurich, Switzerland). 14: 137-47. PMID 15193026 DOI: 10.1111/J.1750-3639.2004.Tb00046.X  0.362
2004 Vidal R, Ghetti B, Takao M, Brefel-Courbon C, Uro-Coste E, Glazier BS, Siani V, Benson MD, Calvas P, Miravalle L, Rascol O, Delisle MB. Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene. Journal of Neuropathology and Experimental Neurology. 63: 363-80. PMID 15099026 DOI: 10.1093/Jnen/63.4.363  0.396
2004 Choi SI, Vidal R, Frangione B, Levy E. Axonal transport of British and Danish amyloid peptides via secretory vesicles. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 373-5. PMID 14656991 DOI: 10.1096/Fj.03-0730Fje  0.342
2004 Roher AE, Kokjohn TA, Esh C, Weiss N, Childress J, Kalback W, Luehrs DC, Lopez J, Brune D, Kuo YM, Farlow M, Murrell J, Vidal R, Ghetti B. The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates. The Journal of Biological Chemistry. 279: 5829-36. PMID 14645225 DOI: 10.1074/Jbc.M311380200  0.474
2004 Miravalle L, Ghetti B, Calero M, Rentz CA, Richardson RM, Takao M, Vidal R. P1-216 Cotton wool plaques associated with a novel mutation in the presenilin 1 gene (V261I): immunohistological, genetic and biochemicals studies Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80529-3  0.322
2002 Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, Guerin CJ, Gibb G, Hanger DP, Rostagno A, Anderton BH, Strand C, Ayling H, Plant G, Frangione B, Bojsen-Møller M, et al. Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. Journal of Neuropathology and Experimental Neurology. 61: 254-67. PMID 11895040 DOI: 10.1093/Jnen/61.3.254  0.478
2001 Ghiso J, Révész T, Holton J, Rostagno A, Lashley T, Houlden H, Gibb G, Anderton B, Bek T, Bojsen-Møller M, Wood N, Vidal R, Braendgaard H, Plant G, Frangione B. Chromosome 13 dementia syndromes as models of neurodegeneration. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 8: 277-84. PMID 11791622 DOI: 10.3109/13506120108993826  0.505
2001 Poeggeler B, Miravalle L, Zagorski MG, Wisniewski T, Chyan YJ, Zhang Y, Shao H, Bryant-Thomas T, Vidal R, Frangione B, Ghiso J, Pappolla MA. Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide. Biochemistry. 40: 14995-5001. PMID 11732920 DOI: 10.1021/Bi0114269  0.45
2001 Ghiso JA, Holton J, Miravalle L, Calero M, Lashley T, Vidal R, Houlden H, Wood N, Neubert TA, Rostagno A, Plant G, Revesz T, Frangione B. Systemic amyloid deposits in familial British dementia. The Journal of Biological Chemistry. 276: 43909-14. PMID 11557758 DOI: 10.1074/Jbc.M105956200  0.507
2001 Teng MH, Yin JY, Vidal R, Ghiso J, Kumar A, Rabenou R, Shah A, Jacobson DR, Tagoe C, Gallo G, Buxbaum J. Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: A possible model for senile systemic amyloidosis Laboratory Investigation. 81: 385-396. PMID 11310831 DOI: 10.1038/Labinvest.3780246  0.419
2001 Vidal R, Calero M, Révész T, Plant G, Ghiso J, Frangione B. Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family. Gene. 266: 95-102. PMID 11290423 DOI: 10.1016/S0378-1119(01)00374-2  0.341
2001 Holton JL, Ghiso J, Lashley T, Rostagno A, Guerin CJ, Gibb G, Houlden H, Ayling H, Martinian L, Anderton BH, Wood NW, Vidal R, Plant G, Frangione B, Revesz T. Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. The American Journal of Pathology. 158: 515-26. PMID 11159188 DOI: 10.1016/S0002-9440(10)63993-4  0.44
2000 Ghiso J, Vidal R, Rostagno A, Miravalle L, Holton JL, Mead S, Révész T, Plant G, Frangione B. Amyloidogenesis in familial British dementia is associated with a genetic defect on chromosome 13. Annals of the New York Academy of Sciences. 920: 84-92. PMID 11193180 DOI: 10.1111/J.1749-6632.2000.Tb06908.X  0.492
2000 Vidal R, Ghiso J, Frangione B. New familial forms of cerebral amyloid and dementia. Molecular Psychiatry. 5: 575-6. PMID 11126387 DOI: 10.1038/Sj.Mp.4000797  0.395
2000 Vidal R, Calero M, Piccardo P, Farlow MR, Unverzagt FW, Méndez E, Jiménez-Huete A, Beavis R, Gallo G, Gomez-Tortosa E, Ghiso J, Hyman BT, Frangione B, Ghetti B. Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele. Acta Neuropathologica. 100: 1-12. PMID 10912914 DOI: 10.1007/S004010051186  0.484
2000 Frangione B, Vidal R, Rostagno A, Ghiso J. Familial cerebral amyloid angiopathies and dementia. Alzheimer Disease and Associated Disorders. 14: S25-30. PMID 10850727 DOI: 10.1097/00002093-200000001-00005  0.467
2000 Ghiso J, Vidal R, Rostagno A, Mead S, Révész T, Plant G, Frangione B. A newly formed amyloidogenic fragment due to a stop codon mutation causes familial British dementia. Annals of the New York Academy of Sciences. 903: 129-37. PMID 10818498 DOI: 10.1111/J.1749-6632.2000.Tb06359.X  0.488
2000 Tokuda T, Calero M, Matsubara E, Vidal R, Kumar A, Permanne B, Zlokovic B, Smith JD, Ladu MJ, Rostagno A, Frangione B, Ghiso J. Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides. The Biochemical Journal. 348: 359-65. PMID 10816430 DOI: 10.1042/0264-6021:3480359  0.409
2000 Vidal R, Revesz T, Rostagno A, Kim E, Holton JL, Bek T, Bojsen-Møller M, Braendgaard H, Plant G, Ghiso J, Frangione B. A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred. Proceedings of the National Academy of Sciences of the United States of America. 97: 4920-5. PMID 10781099 DOI: 10.1073/Pnas.080076097  0.495
2000 Vidal RG, Calero M, Ghiso J, Frangione B. BRI amyloid precursor protein isoforms. BRI2 is mutated in familial British dementia Neurobiology of Aging. 21: 13. DOI: 10.1016/S0197-4580(00)82737-2  0.432
2000 Miravalle L, Vidal RG, Calero M, Révész T, Plant G, Frangione B, Ghiso J. N-terminal pyroglutamate enhances the fibrillogenic properties of the ABRI peptide in familial British dementia Neurobiology of Aging. 21: 84. DOI: 10.1016/S0197-4580(00)82600-7  0.319
2000 Vidal RG, Révész T, Rostagno A, Bek T, Braendgaard H, Plant G, Ghiso J, Frangione B. A decamer duplication in the BRI gene originates a de-novo amyloid peptide that causes dementia in a Danish kindred Neurobiology of Aging. 21: 58. DOI: 10.1016/S0197-4580(00)82484-7  0.397
2000 Révész T, Holton JL, Vidal RG, Rostagno A, Lashley T, Plant G, Frangione B, Ghiso J. Cerebral deposition of ABRI amyloid in familial British dementia Neurobiology of Aging. 21: 191. DOI: 10.1016/S0197-4580(00)82203-4  0.413
1999 Rostagno A, Vidal R, Kaplan B, Chuba J, Kumar A, Elliott JI, Frangione B, Gallo G, Ghiso J. pH-dependent fibrillogenesis of a VkappaIII Bence Jones protein. British Journal of Haematology. 107: 835-43. PMID 10606892 DOI: 10.1046/J.1365-2141.1999.01778.X  0.33
1999 Vidal R, Goñi F, Stevens F, Aucouturier P, Kumar A, Frangione B, Ghiso J, Gallo G. Somatic mutations of the L12a gene in V-kappa(1) light chain deposition disease: potential effects on aberrant protein conformation and deposition. The American Journal of Pathology. 155: 2009-17. PMID 10595931 DOI: 10.1016/S0002-9440(10)65520-4  0.354
1999 Kaplan B, Vidal R, Kumar A, Ghiso J, Gallo G. Immunochemical microanalysis of amyloid proteins in fine-needle aspirates of abdominal fat. American Journal of Clinical Pathology. 112: 403-407. PMID 10478147 DOI: 10.1093/Ajcp/112.3.403  0.4
1999 Vidal R, Frangione B, Rostagno A, Mead S, Révész T, Plant G, Ghiso J. A stop-codon mutation in the BRI gene associated with familial British dementia. Nature. 399: 776-81. PMID 10391242 DOI: 10.1038/21637  0.488
1998 Jiménez-Huete A, Lievens PM, Vidal R, Piccardo P, Ghetti B, Tagliavini F, Frangione B, Prelli F. Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. The American Journal of Pathology. 153: 1561-72. PMID 9811348 DOI: 10.1016/S0002-9440(10)65744-6  0.344
1998 Decourt C, Touchard G, Preud'homme JL, Vidal R, Beaufils H, Diemert MC, Cogné M. Complete primary sequences of two λ immunoglobulin light chains in myelomas with nonamyloid (Randall-type) light chain deposition disease American Journal of Pathology. 153: 313-318. PMID 9665493 DOI: 10.1016/S0002-9440(10)65573-3  0.329
1997 Kaplan B, Vidal R, Kumar A, Ghiso J, Frangione B, Gallo G. Amino-terminal identity of co-existent amyloid and non-amyloid immunoglobulin kappa light chain deposits. A human disease to study alterations of protein conformation. Clinical and Experimental Immunology. 110: 472-8. PMID 9409653 DOI: 10.1046/J.1365-2249.1997.4421454.X  0.424
1996 Rostagno A, Vidal R, Kumar A, Chuba J, Niederman G, Gold L, Frangione B, Ghiso J, Gallo G. Fibrillary glomerulonephritis related to serum fibrillar immunoglobulin-fibronectin complexes. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 28: 676-84. PMID 9158204 DOI: 10.1016/S0272-6386(96)90248-6  0.367
1996 Frangione B, Castaño EM, Wisniewski T, Ghiso J, Prelli F, Vidal R. Apolipoprotein E and amyloidogenesis. Ciba Foundation Symposium. 199: 132-41; discussion 1. PMID 8915608 DOI: 10.1002/9780470514924.Ch9  0.362
1996 Vidal R, Ghiso J, Wisniewski T, Frangione B. Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes. Identification of a novel splice variant. Febs Letters. 393: 19-23. PMID 8804415 DOI: 10.1016/0014-5793(96)00845-9  0.352
1996 Perini F, Vidal R, Ghetti B, Tagliavini F, Frangione B, Prelli F. PrP27-30 is a normal soluble prion protein fragment released by human platelets. Biochemical and Biophysical Research Communications. 223: 572-7. PMID 8687437 DOI: 10.1006/Bbrc.1996.0936  0.332
1996 Frangione B, Perini F, Vidal R, Tagliavini F, Ghetti B, Prelli F. 162 Alzheimer's and prion diseases: Soluble proteins are altered in the brain. Why? Neurobiology of Aging. 17: S41. DOI: 10.1016/S0197-4580(96)80164-3  0.377
1993 Vidal RG, Fernandez-Madrid I, Frangione B, Levy E. Sequencing of the Alzheimer's APP gene Dutch variant (APP-D) Human Mutation. 2: 496-7. PMID 8111419 DOI: 10.1002/Humu.1380020613  0.354
1992 Vidal RG, Ghiso J, Gallo G, Cohen M, Gambetti PL, Frangione B. Amyloidoma of the CNS. II. Immunohistochemical and biochemical study. Neurology. 42: 2024-8. PMID 1383872 DOI: 10.1212/Wnl.42.10.2024  0.432
1992 Ghiso J, Wisniewski T, Vidal R, Rostagno A, Frangione B. Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease. The Biochemical Journal. 282: 517-22. PMID 1372166 DOI: 10.1042/Bj2820517  0.382
Low-probability matches (unlikely to be authored by this person)
2022 Björk L, Bäck M, Lantz L, Ghetti B, Vidal R, Klingstedt T, Nilsson P. Proteophenes - amino acid functionalized thiophene-based fluorescent ligands for visualization of protein deposits in tissue sections with Alzheimer´s disease pathology. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35950816 DOI: 10.1002/chem.202201557  0.3
2005 Foroud T, Pankratz N, Batchman AP, Pauciulo MW, Vidal R, Miravalle L, Goebel HH, Cushman LJ, Azzarelli B, Horak H, Farlow M, Nichols WC. A mutation in myotilin causes spheroid body myopathy. Neurology. 65: 1936-40. PMID 16380616 DOI: 10.1212/01.Wnl.0000188872.28149.9A  0.298
2011 Farrow EG, Yu X, Summers LJ, Davis SI, Fleet JC, Allen MR, Robling AG, Stayrook KR, Jideonwo V, Magers MJ, Garringer HJ, Vidal R, Chan RJ, Goodwin CB, Hui SL, et al. Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: E1146-55. PMID 22006328 DOI: 10.1073/Pnas.1110905108  0.297
2000 Askanas V, Engel WK, Alvarez RB, Frangione B, Ghiso J, Vidal R. Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele. Annals of Neurology. 47: 544-9. PMID 10762172 DOI: 10.1002/1531-8249(200004)47:4<544::Aid-Ana24>3.0.Co;2-D  0.283
2009 Xiao X, Miravalle L, Yuan J, McGeehan J, Dong Z, Wyza R, MacLennan GT, Golichowski AM, Kneale G, King N, Kong Q, Spina S, Vidal R, Ghetti B, Roos K, et al. Failure to detect the presence of prions in the uterine and gestational tissues from a Gravida with Creutzfeldt-Jakob disease. The American Journal of Pathology. 174: 1602-8. PMID 19349373 DOI: 10.2353/Ajpath.2009.081045  0.281
2023 Schweighauser M, Garringer HJ, Klingstedt T, Nilsson KPR, Masuda-Suzukake M, Murrell JR, Risacher SL, Vidal R, Scheres SHW, Goedert M, Ghetti B, Newell KL. Mutation ∆K281 in MAPT causes Pick's disease. Acta Neuropathologica. 146: 211-226. PMID 37351604 DOI: 10.1007/s00401-023-02598-6  0.277
2008 Spina S, Murrell JR, Vidal R, Ghetti B. P2-205: Neuropathologic and genetic characterization of frontotemporal lobar degeneration with ubiquitin- and/or TDP-43-positive inclusions: A large series Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1280  0.272
1999 Déret S, Denoroy L, Lamarine M, Vidal R, Mougenot B, Frangione B, Stevens FJ, Ronco PM, Aucouturier P. Kappa light chain-associated Fanconi's syndrome: molecular analysis of monoclonal immunoglobulin light chains from patients with and without intracellular crystals. Protein Engineering. 12: 363-9. PMID 10325408 DOI: 10.1093/Protein/12.4.363  0.27
2023 Rajewski BH, Makwana KM, Angera IJ, Geremia DK, Zepeda AR, Hallinan GI, Vidal R, Ghetti B, Serrano AL, Del Valle JR. β-Bracelets: Macrocyclic Cross-β Epitope Mimics Based on a Tau Conformational Strain. Journal of the American Chemical Society. 145: 23131-23142. PMID 37844142 DOI: 10.1021/jacs.3c06830  0.267
2010 Unverzagt FW, Farlow MR, Gao S, Saykin AJ, Murrell JR, Risacher SL, Lane KA, West JD, Matthews BR, Piccardo P, Miravalle L, Vidal RG, Ghetti B. P3-156: Cognition and brain structure in Gerstmann-Straussler-Scheinker disease (PRNP F198S) Alzheimer's & Dementia. 6: S495-S495. DOI: 10.1016/J.Jalz.2010.05.1654  0.263
2004 Azzarelli B, Miravalle L, Vidal R. Immunolocalization of the oligodendrocyte transcription factor 1 (Olig1) in brain tumors. Journal of Neuropathology and Experimental Neurology. 63: 170-9. PMID 14989603 DOI: 10.1093/Jnen/63.2.170  0.263
2010 Prelli F, Vidal R, Wisniewski T. A novel tissue culture model of sporadic Creutzfeldt-Jakob disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.721  0.261
2023 Lantz L, Shirani H, Ghetti B, Vidal R, Klingstedt T, Nilsson P. Thiophene-Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer´s Disease. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36645413 DOI: 10.1002/chem.202203568  0.261
2020 Rajalingam S, Kambrath AV, Vidal R, Willis MS. Deletion of the Microtubule‐associated protein tau (Mapt−/−) results in diastolic heart failure and altered skeletal muscle function in vivo The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02885  0.259
2023 Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B. TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature. PMID 37532939 DOI: 10.1038/s41586-023-06405-w  0.255
2021 Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathologica. PMID 33723967 DOI: 10.1007/s00401-021-02294-3  0.252
2023 Hoq MR, Bharath SR, Hallinan GI, Fernandez A, Vago FS, Ozcan KA, Li D, Garringer HJ, Vidal R, Ghetti B, Jiang W. Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia. Biorxiv : the Preprint Server For Biology. PMID 36711790 DOI: 10.1101/2023.01.09.523314  0.247
2022 Cracco L, Doud EH, Hallinan GI, Garringer HJ, Jacobsen MH, Richardson RM, Buratti E, Vidal R, Ghetti B, Newell KL. Distinguishing post-translational modifications in dominantly inherited frontotemporal dementias: FTLD-TDP Type A (GRN) vs Type B (C9orf72). Neuropathology and Applied Neurobiology. e12836. PMID 35836354 DOI: 10.1111/nan.12836  0.232
2021 Todarwal Y, Gustafsson C, Thi Minh NN, Ertzgaard I, Klingstedt T, Ghetti B, Vidal R, König C, Lindgren M, Nilsson KPR, Linares M, Norman P. Tau Protein Binding Modes in Alzheimer's Disease for Cationic Luminescent Ligands. The Journal of Physical Chemistry. B. 125: 11628-11636. PMID 34643404 DOI: 10.1021/acs.jpcb.1c06019  0.23
2010 Pankiewicz J, Asuni A, Kascak R, Kascak R, Prelli F, Vidal R, Sadowski M. P3-353: Therapeutic mechanisms of anti-prion monoclonal antibodies Alzheimer's & Dementia. 6: S555-S555. DOI: 10.1016/J.Jalz.2010.05.1895  0.225
2020 Irimia-Dominguez J, Sun C, Li K, Muhoberac BB, Hallinan GI, Garringer HJ, Ghetti B, Jiang W, Vidal R. Cryo-EM structures and functional characterization of homo- and heteropolymers of human ferritin variants. Scientific Reports. 10: 20666. PMID 33244127 DOI: 10.1038/s41598-020-77717-4  0.224
2021 Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Correction to: Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathologica. PMID 33830331 DOI: 10.1007/s00401-021-02303-5  0.222
2004 Vidal R, Ghetti B, Delisle MB, Rascol O, Perry G, Smith MA. P4-242 Oxidative damage in ferritin-induced neurodegeneration Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81800-1  0.219
2023 Yang Y, Garringer HJ, Shi Y, Lövestam S, Peak-Chew S, Zhang X, Kotecha A, Bacioglu M, Koto A, Takao M, Spillantini MG, Ghetti B, Vidal R, Murzin AG, Scheres SHW, et al. New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathologica. PMID 36847833 DOI: 10.1007/s00401-023-02550-8  0.212
2019 Li K, Sun C, Klose T, Irimia-Dominguez J, Vago FS, Vidal R, Jiang W. Sub-3 Å Apoferritin Structure Determined With Full Range of Phase Shifts Using A Single Position Of Volta Phase Plate. Journal of Structural Biology. PMID 30928614 DOI: 10.1016/J.Jsb.2019.03.007  0.21
2022 Yang Y, Arseni D, Zhang W, Huang M, Lövestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, ... Vidal R, et al. Cryo-EM structures of amyloid-β 42 filaments from human brains. Science (New York, N.Y.). 375: 167-172. PMID 35025654 DOI: 10.1126/science.abm7285  0.197
2023 Hoq MR, Bharath SR, Hallinan GI, Fernandez A, Vago FS, Ozcan KA, Li D, Garringer HJ, Vidal R, Ghetti B, Jiang W. Cross-β helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia. Acta Neuropathologica. PMID 36952000 DOI: 10.1007/s00401-023-02563-3  0.193
2020 Sun C, Li K, Klose T, Irimia-Dominguez J, Vago F, Vidal R, Jiang W. Sub-3 Å Apoferritin Structure Determined with Single Position of Volta Phase Plate and Full Range of Phase Shift Microscopy and Microanalysis. 1-3. DOI: 10.1017/S1431927620021121  0.189
1993 Freedberg IM, Ohtsuki M, Magnaldo T, Bernerd F, Vidal R, Blumenberg M. Complexes of multiple transcription factors in regulation of keratin synthesis Journal of Dermatological Science. 6: 31. DOI: 10.1016/0923-1811(93)90910-H  0.185
2022 Taylor X, Cisternas P, Jury N, Martinez P, Huang X, You Y, Redding-Ochoa J, Vidal R, Zhang J, Troncoso J, Lasagna-Reeves CA. Activated endothelial cells induce a distinct type of astrocytic reactivity. Communications Biology. 5: 282. PMID 35351973 DOI: 10.1038/s42003-022-03237-8  0.183
2022 Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, et al. Structures of α-synuclein filaments from human brains with Lewy pathology. Nature. PMID 36108674 DOI: 10.1038/s41586-022-05319-3  0.16
2003 Vidal R, Delisle MB, Rascol O, Ghetti B. Hereditary ferritinopathy. Journal of the Neurological Sciences. 207: 110-1. PMID 12614943  0.147
1993 Magnaldo T, Vidal RG, Ohtsuki M, Freedberg IM, Blumenberg M. On the role of AP2 in epithelial-specific gene expression. Gene Expression. 3: 307-15. PMID 7517240  0.067
2009 Joan MM, Moya BG, Agustí FP, Vidal RG, Arjona YA, Alija MP, Paredero VM. Utility of intravascular ultrasound examination during carotid stenting. Annals of Vascular Surgery. 23: 606-11. PMID 19556101 DOI: 10.1016/j.avsg.2008.09.010  0.011
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