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Year Citation  Score
2013 Greenberg BD, Carrillo MC, Ryan JM, Gold M, Gallagher K, Grundman M, Berman RM, Ashwood T, Siemers ER. Improving Alzheimer's disease phase II clinical trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 39-49. PMID 23164548 DOI: 10.1016/j.jalz.2012.02.002  0.96
2011 Shineman DW, Basi GS, Bizon JL, Colton CA, Greenberg BD, Hollister BA, Lincecum J, Leblanc GG, Lee LB, Luo F, Morgan D, Morse I, Refolo LM, Riddell DR, Scearce-Levie K, et al. Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies. Alzheimer's Research & Therapy. 3: 28. PMID 21943025 DOI: 10.1186/alzrt90  0.96
2011 Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, et al. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 127-32. PMID 21414553 DOI: 10.1016/j.jalz.2011.02.005  0.96
2010 Khachaturian ZS, Barnes D, Einstein R, Johnson S, Lee V, Roses A, Sager MA, Shankle WR, Snyder PJ, Petersen RC, Schellenberg G, Trojanowski J, Aisen P, Albert MS, Breitner JC, ... ... Greenberg BD, et al. Developing a national strategy to prevent dementia: Leon Thal Symposium 2009. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 89-97. PMID 20298968 DOI: 10.1016/j.jalz.2010.01.008  0.96
2007 Morissette C, Lacombe D, Kong X, Aman A, Krzywkowski P, Rodionova L, Azzi M, Delorme D, Greenberg BD. Potential applications of glycosaminoglycan-related compounds in Alzheimer's disease Pharmacological Mechanisms in Alzheimer's Therapeutics. 255-273. DOI: 10.1007/978-0-387-71522-3_16  0.96
2004 Knappenberger KS, Tian G, Ye X, Sobotka-Briner C, Ghanekar SV, Greenberg BD, Scott CW. Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop? Biochemistry. 43: 6208-18. PMID 15147205 DOI: 10.1021/bi036072v  0.96
2003 Tian G, Ghanekar SV, Aharony D, Shenvi AB, Jacobs RT, Liu X, Greenberg BD. The mechanism of gamma-secretase: multiple inhibitor binding sites for transition state analogs and small molecule inhibitors. The Journal of Biological Chemistry. 278: 28968-75. PMID 12719412 DOI: 10.1074/jbc.M300905200  0.96
2002 Tian G, Sobotka-Briner CD, Zysk J, Liu X, Birr C, Sylvester MA, Edwards PD, Scott CD, Greenberg BD. Linear non-competitive inhibition of solubilized human gamma-secretase by pepstatin A methylester, L685458, sulfonamides, and benzodiazepines. The Journal of Biological Chemistry. 277: 31499-505. PMID 12072428 DOI: 10.1074/jbc.M112328200  0.96
2002 Zhang J, Ye W, Wang R, Wolfe MS, Greenberg BD, Selkoe DJ. Proteolysis of chimeric beta-amyloid precursor proteins containing the Notch transmembrane domain yields amyloid beta-like peptides. The Journal of Biological Chemistry. 277: 15069-75. PMID 11839734 DOI: 10.1074/jbc.M105375200  0.96
2000 Horsburgh K, Cole GM, Yang F, Savage MJ, Greenberg BD, Gentleman SM, Graham DI, Nicoll JA. beta-amyloid (Abeta)42(43), abeta42, abeta40 and apoE immunostaining of plaques in fatal head injury. Neuropathology and Applied Neurobiology. 26: 124-32. PMID 10840275 DOI: 10.1046/j.1365-2990.2000.026002124.x  0.96
1999 Durkin JT, Murthy S, Husten EJ, Trusko SP, Savage MJ, Rotella DP, Greenberg BD, Siman R. Rank-order of potencies for inhibition of the secretion of abeta40 and abeta42 suggests that both are generated by a single gamma-secretase. The Journal of Biological Chemistry. 274: 20499-504. PMID 10400678 DOI: 10.1074/jbc.274.29.20499  0.96
1998 Howland DS, Trusko SP, Savage MJ, Reaume AG, Lang DM, Hirsch JD, Maeda N, Siman R, Greenberg BD, Scott RW, Flood DG. Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. The Journal of Biological Chemistry. 273: 16576-82. PMID 9632729 DOI: 10.1074/jbc.273.26.16576  0.96
1998 Savage MJ, Trusko SP, Howland DS, Pinsker LR, Mistretta S, Reaume AG, Greenberg BD, Siman R, Scott RW. Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1743-52. PMID 9464999  0.96
1997 Chyung AS, Greenberg BD, Cook DG, Doms RW, Lee VM. Novel beta-secretase cleavage of beta-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells. The Journal of Cell Biology. 138: 671-80. PMID 9245794 DOI: 10.1083/jcb.138.3.671  0.96
1997 Gentleman SM, Greenberg BD, Savage MJ, Noori M, Newman SJ, Roberts GW, Griffin WS, Graham DI. A beta 42 is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury. Neuroreport. 8: 1519-22. PMID 9172166  0.96
1997 Leveugle B, Ding W, Durkin JT, Mistretta S, Eisle J, Matic M, Siman R, Greenberg BD, Fillit HM. Heparin promotes beta-secretase cleavage of the Alzheimer's amyloid precursor protein. Neurochemistry International. 30: 543-8. PMID 9152995 DOI: 10.1016/S0197-0186(96)00103-9  0.96
1996 Greenberg BD. Alzheimer's disease pathogenesis: the challenge of establishing dynamic biological processes from static measurements. Neurobiology of Aging. 17: 938-9; discussion 94. PMID 9363807 DOI: 10.1016/S0197-4580(96)00175-3  0.96
1996 Kalaria RN, Cohen DL, Greenberg BD, Savage MJ, Bogdanovic NE, Winblad B, Lannfelt L, Adem A. Abundance of the longer A beta 42 in neocortical and cerebrovascular amyloid beta deposits in Swedish familial Alzheimer's disease and Down's syndrome. Neuroreport. 7: 1377-81. PMID 8856679  0.96
1996 Cummings BJ, Satou T, Head E, Milgram NW, Cole GM, Savage MJ, Podlisny MB, Selkoe DJ, Siman R, Greenberg BD, Cotman CW. Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs. Neurobiology of Aging. 17: 653-9. PMID 8832640  0.96
1996 Reaume AG, Howland DS, Trusko SP, Savage MJ, Lang DM, Greenberg BD, Siman R, Scott RW. Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence. The Journal of Biological Chemistry. 271: 23380-8. PMID 8798542 DOI: 10.1074/jbc.271.38.23380  0.96
1996 Ali SM, Siedlak SL, Gonzalez-DeWhitt PA, Altman RA, Glendening JM, Lowery DE, Savage MJ, Polites HG, Perry G, Greenberg BD. Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice. Neurobiology of Aging. 17: 223-34. PMID 8744403 DOI: 10.1016/0197-4580(95)02065-9  0.96
1996 Greenberg BD, Savage MJ, Howland DS, Ali SM, Siedlak SL, Perry G, Siman R, Scott RW. APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiology of Aging. 17: 153-71. PMID 8744397 DOI: 10.1016/0197-4580(96)00001-2  0.96
1996 Kuentzel SL, Gonzalez-DeWhitt PA, Lowery DE, Altman RA, Leone JW, Heinrikson RL, Greenberg BD, Raub TJ. Overexpression of a COOH-terminal fragment of β-amyloid precursor protein in HeLa cells results in accumulation in a pre-Golgi compartment and generation of an Aβ-like fragment Amyloid. 3: 86-99.  0.96
1995 Howland DS, Savage MJ, Huntress FA, Wallace RE, Schwartz DA, Loh T, Melloni RH, DeGennaro LJ, Greenberg BD, Siman R. Mutant and native human beta-amyloid precursor proteins in transgenic mouse brain. Neurobiology of Aging. 16: 685-99. PMID 8544921 DOI: 10.1016/0197-4580(95)00078-S  0.96
1995 Narindrasorasak S, Altman RA, Gonzalez-DeWhitt P, Greenberg BD, Kisilevsky R. An interaction between basement membrane and Alzheimer amyloid precursor proteins suggests a role in the pathogenesis of Alzheimer's disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 72: 272-82. PMID 7898047  0.96
1995 Carter RE, Cerosaletti KM, Burkin DJ, Fournier RE, Jones C, Greenberg BD, Citron BA, Festoff BW. The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes. Genomics. 27: 196-9. PMID 7665170 DOI: 10.1006/geno.1995.1025  0.96
1994 Akaaboune M, Ma J, Festoff BW, Greenberg BD, Hantaï D. Neurotrophic regulation of mouse muscle beta-amyloid protein precursor and alpha 1-antichymotrypsin as revealed by axotomy. Journal of Neurobiology. 25: 503-14. PMID 8071658 DOI: 10.1002/neu.480250505  0.96
1994 Geula C, Greenberg BD, Mesulam MM. Cholinesterase activity in the plaques, tangles and angiopathy of Alzheimer's disease does not emanate from amyloid. Brain Research. 644: 327-30. PMID 8050043 DOI: 10.1016/0006-8993(94)91697-7  0.96
1994 Greenberg BD, Murphy MF. Toward an integrated discovery and development program in Alzheimer's disease: the amyloid hypothesis. Neurobiology of Aging. 15: S105-9. PMID 7700430 DOI: 10.1016/0197-4580(94)90184-8  0.96
1993 Kuentzel SL, Ali SM, Altman RA, Greenberg BD, Raub TJ. The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells. The Biochemical Journal. 295: 367-78. PMID 8240235  0.96
1993 Kawai M, Kalaria RN, Cras P, Siedlak SL, Velasco ME, Shelton ER, Chan HW, Greenberg BD, Perry G. Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Research. 623: 142-6. PMID 8221082 DOI: 10.1016/0006-8993(93)90021-E  0.96
1993 Akaaboune M, Ma J, Festoff BW, Greenberg BD, Hantaï D. The influence of denervation on beta-amyloid protein precursor and alpha 1-antichymotrypsin in mouse skeletal muscle. Neuromuscular Disorders : Nmd. 3: 477-81. PMID 8186697 DOI: 10.1016/0960-8966(93)90100-X  0.96
1993 Perry G, Richey PL, Siedlak SL, Smith MA, Mulvihill P, DeWitt DA, Barnett J, Greenberg BD, Kalaria RN. Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease. The American Journal of Pathology. 143: 1586-93. PMID 7504885  0.96
1992 Estus S, Golde TE, Kunishita T, Blades D, Lowery D, Eisen M, Usiak M, Qu XM, Tabira T, Greenberg BD. Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor. Science (New York, N.Y.). 255: 726-8. PMID 1738846  0.96
1992 Kawai M, Cras P, Richey P, Tabaton M, Lowery DE, Gonzalez-DeWhitt PA, Greenberg BD, Gambetti P, Perry G. Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease. The American Journal of Pathology. 140: 947-58. PMID 1562053  0.96
1992 Narindrasorasak S, Lowery DE, Altman RA, Gonzalez-DeWhitt PA, Greenberg BD, Kisilevsky R. Characterization of high affinity binding between laminin and Alzheimer's disease amyloid precursor proteins. Laboratory Investigation; a Journal of Technical Methods and Pathology. 67: 643-52. PMID 1434542  0.96
1992 Murphy GM, Greenberg BD, Ellis WG, Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lowery DE, Tinklenberg JR, Eng LF. Alzheimer's disease. Beta-amyloid precursor protein expression in the nucleus basalis of Meynert. The American Journal of Pathology. 141: 357-61. PMID 1386714  0.96
1991 Buxser S, Vroegop S, Decker D, Hinzmann J, Poorman R, Thomsen DR, Stier M, Abraham I, Greenberg BD, Hatzenbuhler NT. Single-step purification and biological activity of human nerve growth factor produced from insect cells. Journal of Neurochemistry. 56: 1012-8. PMID 1993887  0.96
1991 Perry G, Siedlak SL, Richey P, Kawai M, Cras P, Kalaria RN, Galloway PG, Scardina JM, Cordell B, Greenberg BD. Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3679-83. PMID 1941102  0.96
1991 Lowery DE, Pasternack JM, Gonzalez-DeWhitt PA, Zürcher-Neely H, Tomich CC, Altman RA, Fairbanks MB, Heinrikson RL, Younkin SG, Greenberg BD. Alzheimer's amyloid precursor protein produced by recombinant baculovirus expression. Proteolytic processing and protease inhibitory properties. The Journal of Biological Chemistry. 266: 19842-50. PMID 1918088  0.96
1991 Murphy GM, Murphy E, Greenberg BD, Cordell B, Eng LF, Ellis WG, Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lowery DE. Alzheimer's disease: beta-amyloid precursor protein expression in plaques varies among cytoarchitectonic areas of the medial temporal lobe. Neuroscience Letters. 131: 100-4. PMID 1791966  0.68
1991 Arai H, Lee VM, Messinger ML, Greenberg BD, Lowery DE, Trojanowski JQ. Expression patterns of beta-amyloid precursor protein (beta-APP) in neural and nonneural human tissues from Alzheimer's disease and control subjects. Annals of Neurology. 30: 686-93. PMID 1763893 DOI: 10.1002/ana.410300509  0.68
1991 Standaert DG, Lee VM, Greenberg BD, Lowery DE, Trojanowski JQ. Molecular features of hypothalamic plaques in Alzheimer's disease. The American Journal of Pathology. 139: 681-91. PMID 1653521  0.96
1990 Arai H, Lee VM, Otvos L, Greenberg BD, Lowery DE, Sharma SK, Schmidt ML, Trojanowski JQ. Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques. Proceedings of the National Academy of Sciences of the United States of America. 87: 2249-53. PMID 1690426  0.68
1989 Autilio-Gambetti L, Morandi A, Kovacs DM, Tabaton M, Schaetzle B, Hauer C, Groger RK, Tykocinski ML, Perry G, Greenberg BD. Amyloid precursor protein in cell cultures: a 130 kDa polypeptide. Progress in Clinical and Biological Research. 317: 985-90. PMID 2574879  0.96
1987 Wallace DC, Ye JH, Neckelmann SN, Singh G, Webster KA, Greenberg BD. Sequence analysis of cDNAs for the human and bovine ATP synthase beta subunit: mitochondrial DNA genes sustain seventeen times more mutations. Current Genetics. 12: 81-90. PMID 2896550 DOI: 10.1007/BF00434661  0.96
1983 Aquadro CF, Greenberg BD. Human mitochondrial DNA variation and evolution: analysis of nucleotide sequences from seven individuals. Genetics. 103: 287-312. PMID 6299878  0.96
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