William E. Van Nostrand - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 
Area:
Neuroscience Biology, Biochemistry, Cell Biology

125/159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vervuurt M, Schrader JM, de Kort AM, Kersten I, Wessels HJCT, Klijn CJM, Schreuder FHBM, Kuiperij HB, Gloerich J, Van Nostrand WE, Verbeek MM. Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients. Acta Neuropathologica Communications. 12: 6. PMID 38191511 DOI: 10.1186/s40478-023-01698-4  0.323
2023 Ambi A, Stanisavljevic A, Victor TW, Lowery AW, Davis J, Van Nostrand WE, Miller LM. Evaluation of Copper Chelation Therapy in a Transgenic Rat Model of Cerebral Amyloid Angiopathy. Acs Chemical Neuroscience. PMID 36651175 DOI: 10.1021/acschemneuro.2c00483  0.439
2022 Zhu X, Schrader JM, Irizarry BA, Smith SO, Van Nostrand WE. Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Biomedicines. 10. PMID 36428550 DOI: 10.3390/biomedicines10112982  0.474
2022 Davis J, Xu F, Zhu X, Van Nostrand WE. rTg-D: A novel transgenic rat model of cerebral amyloid angiopathy Type-2. Cerebral Circulation - Cognition and Behavior. 3: 100133. PMID 36324401 DOI: 10.1016/j.cccb.2022.100133  0.349
2022 Rajpoot J, Crooks EJ, Irizarry BA, Amundson A, Van Nostrand WE, Smith SO. Insights into Cerebral Amyloid Angiopathy Type 1 and Type 2 from Comparisons of the Fibrillar Assembly and Stability of the Aβ40-Iowa and Aβ40-Dutch Peptides. Biochemistry. PMID 35666749 DOI: 10.1021/acs.biochem.1c00781  0.563
2022 Stanisavljevic A, Schrader JM, Zhu X, Mattar JM, Hanks A, Xu F, Majchrzak M, Robinson JK, Van Nostrand WE. Impact of Non-pharmacological Chronic Hypertension on a Transgenic Rat Model of Cerebral Amyloid Angiopathy. Frontiers in Neuroscience. 16: 811371. PMID 35368255 DOI: 10.3389/fnins.2022.811371  0.308
2022 Vervuurt M, Zhu X, Schrader J, de Kort AM, Marques TM, Kersten I, Peters van Ton AM, Abdo WF, Schreuder FHBM, Rasing I, Terwindt GM, Wermer MJH, Greenberg SM, Klijn CJM, Kuiperij HB, ... Van Nostrand WE, et al. Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy. Neuropathology and Applied Neurobiology. e12804. PMID 35266166 DOI: 10.1111/nan.12804  0.386
2021 De Kort AM, Kuiperij HB, Kersten I, Versleijen AAM, Schreuder FHBM, Van Nostrand WE, Greenberg SM, Klijn CJM, Claassen JAHR, Verbeek MM. Normal cerebrospinal fluid concentrations of PDGFRβ in patients with cerebral amyloid angiopathy and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34874603 DOI: 10.1002/alz.12506  0.366
2021 Irizarry BA, Davis J, Zhu X, Boon BDC, Rozemuller AJM, Van Nostrand WE, Smith SO. Human cerebral vascular amyloid contains both anti-parallel and parallel in-register Aβ40 fibrils. The Journal of Biological Chemistry. 101259. PMID 34599967 DOI: 10.1016/j.jbc.2021.101259  0.531
2021 Schrader JM, Xu F, Van Nostrand WE. Distinct brain regional proteome changes in the rTg-DI rat model of cerebral amyloid angiopathy. Journal of Neurochemistry. PMID 34218440 DOI: 10.1111/jnc.15463  0.359
2021 Fu Z, Van Nostrand WE, Smith SO. Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa. International Journal of Molecular Sciences. 22. PMID 33513738 DOI: 10.3390/ijms22031225  0.512
2020 Boon BDC, Bulk M, Jonker AJ, Morrema THJ, van den Berg E, Popovic M, Walter J, Kumar S, van der Lee SJ, Holstege H, Zhu X, Van Nostrand WE, Natté R, van der Weerd L, Bouwman FH, et al. The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer's disease. Acta Neuropathologica. PMID 32926214 DOI: 10.1007/s00401-020-02198-8  0.453
2020 Crooks EJ, Irizarry BA, Ziliox M, Kawakami T, Victor TW, Xu F, Hojo H, Chiu K, Simmerling C, Van Nostrand WE, Smith SO, Miller LM. Copper stabilizes antiparallel β-sheet fibrils of the amyloid β40 (Aβ40)-Iowa variant. The Journal of Biological Chemistry. PMID 32376688 DOI: 10.1074/Jbc.Ra119.011955  0.55
2020 Popescu DL, Van Nostrand WE, Robinson JK. Longitudinal Cognitive Decline in a Novel Rodent Model of Cerebral Amyloid Angiopathy Type-1. International Journal of Molecular Sciences. 21. PMID 32231123 DOI: 10.3390/Ijms21072348  0.426
2020 Zhu X, Hatfield J, Sullivan JK, Xu F, Van Nostrand WE. Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy. Journal of Neuroinflammation. 17: 78. PMID 32127016 DOI: 10.1186/s12974-020-01755-y  0.361
2020 Zhu X, Victor TW, Ambi A, Sullivan JK, Hatfield J, Xu F, Miller LM, Van Nostrand WE. Copper accumulation and the effect of chelation treatment on cerebral amyloid angiopathy compared to parenchymal amyloid plaques. Metallomics : Integrated Biometal Science. PMID 32104807 DOI: 10.1039/c9mt00306a  0.469
2020 Robison LS, Francis N, Popescu DL, Anderson ME, Hatfield J, Xu F, Anderson BJ, Van Nostrand WE, Robinson JK. Environmental Enrichment: Disentangling the Influence of Novelty, Social, and Physical Activity on Cerebral Amyloid Angiopathy in a Transgenic Mouse Model. International Journal of Molecular Sciences. 21. PMID 32012921 DOI: 10.3390/Ijms21030843  0.328
2019 Robison LS, Popescu DL, Anderson ME, Francis N, Hatfield J, Sullivan JK, Beigelman SI, Xu F, Anderson BJ, Van Nostrand WE, Robinson JK. Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy. Journal of Neuroinflammation. 16: 144. PMID 31296239 DOI: 10.1186/S12974-019-1534-0  0.462
2019 Chen CD, Zeldich E, Khodr C, Camara K, Tung TY, Lauder EC, Mullen P, Polanco TJ, Liu YY, Zeldich D, Xia W, Van Nostrand WE, Brown LE, Porco JA, Abraham CR. Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling. Journal of Alzheimer's Disease : Jad. 67: 1089-1106. PMID 30776010 DOI: 10.3233/Jad-180923  0.41
2018 Davis J, Xu F, Hatfield J, Lee H, Hoos MD, Popescu D, Crooks E, Kim R, Smith SO, Robinson JK, Benveniste H, Van Nostrand WE. A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy. The American Journal of Pathology. PMID 30446159 DOI: 10.1016/J.Ajpath.2018.07.030  0.787
2017 Jäkel L, Van Nostrand WE, Nicoll JAR, Werring DJ, Verbeek MM. Animal models of cerebral amyloid angiopathy. Clinical Science (London, England : 1979). 131: 2469-2488. PMID 28963121 DOI: 10.1042/CS20170033  0.368
2017 Xu F, Davis J, Hoos M, Van Nostrand WE. Mutation of the Kunitz-type proteinase inhibitor domain in the amyloid β-protein precursor abolishes its anti-thrombotic properties in vivo. Thrombosis Research. 155: 58-64. PMID 28499154 DOI: 10.1016/J.Thromres.2017.05.003  0.771
2016 Xu F, Fu Z, Dass S, Kotarba AE, Davis J, Smith SO, Van Nostrand WE. Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure. Nature Communications. 7: 13527. PMID 27869115 DOI: 10.1038/Ncomms13527  0.572
2016 Anderson M, Xu F, Ou-Yang MH, Davis J, Van Nostrand WE, Robinson JK. Intensive 'Brain Training' Intervention Fails to Reduce Amyloid Pathologies or Cognitive Deficits in Transgenic Mouse Models of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27767989 DOI: 10.3233/Jad-160674  0.348
2016 Xu F, Van Nostrand WE. Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice. Data in Brief. 6: 149-52. PMID 26858980 DOI: 10.1016/j.dib.2015.11.050  0.375
2016 Van Nostrand WE. The influence of the amyloid ß-protein and its precursor in modulating cerebral hemostasis. Biochimica Et Biophysica Acta. 1862: 1018-26. PMID 26519139 DOI: 10.1016/j.bbadis.2015.10.020  0.316
2015 Fu Z, Aucoin D, Davis J, Van Nostrand WE, Smith SO. Mechanism of Nucleated Conformational Conversion of Aβ42. Biochemistry. 54: 4197-207. PMID 26069943 DOI: 10.1021/Acs.Biochem.5B00467  0.363
2015 Ou-Yang MH, Xu F, Liao MC, Davis J, Robinson JK, Van Nostrand WE. The N-terminal region of myelin basic protein reduces fibrillar amyloid-β deposition in Tg-5xFAD mice. Neurobiology of Aging. 36: 801-11. PMID 25457550 DOI: 10.1016/J.Neurobiolaging.2014.10.006  0.726
2014 Fu Z, Aucoin D, Ahmed M, Ziliox M, Van Nostrand WE, Smith SO. Capping of aβ42 oligomers by small molecule inhibitors. Biochemistry. 53: 7893-903. PMID 25422864 DOI: 10.1021/Bi500910B  0.438
2014 Xu F, Kotarba AE, Ou-Yang MH, Fu Z, Davis J, Smith SO, Van Nostrand WE. Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice. The Journal of Biological Chemistry. 289: 17895-908. PMID 24828504 DOI: 10.1074/Jbc.M113.536565  0.55
2014 Park L, Koizumi K, El Jamal S, Zhou P, Previti ML, Van Nostrand WE, Carlson G, Iadecola C. Age-dependent neurovascular dysfunction and damage in a mouse model of cerebral amyloid angiopathy. Stroke; a Journal of Cerebral Circulation. 45: 1815-21. PMID 24781082 DOI: 10.1161/Strokeaha.114.005179  0.484
2014 Xu W, Xu F, Anderson ME, Kotarba AE, Davis J, Robinson JK, Van Nostrand WE. Cerebral microvascular rather than parenchymal amyloid-β protein pathology promotes early cognitive impairment in transgenic mice. Journal of Alzheimer's Disease : Jad. 38: 621-32. PMID 24037035 DOI: 10.3233/Jad-130758  0.433
2013 Ou-Yang MH, Van Nostrand WE. The absence of myelin basic protein promotes neuroinflammation and reduces amyloid β-protein accumulation in Tg-5xFAD mice. Journal of Neuroinflammation. 10: 134. PMID 24188129 DOI: 10.1186/1742-2094-10-134  0.524
2013 Hu ZI, Kotarba AM, Van Nostrand WE. Absence of Nitric Oxide Synthase 3 Increases Amyloid β-Protein Pathology in Tg-5xFAD Mice. Neuroscience and Medicine. 4: 84-91. PMID 24159423 DOI: 10.4236/nm.2013.42013  0.672
2013 Kotarba AE, Aucoin D, Hoos MD, Smith SO, Van Nostrand WE. Fine mapping of the amyloid β-protein binding site on myelin basic protein. Biochemistry. 52: 2565-73. PMID 23510371 DOI: 10.1021/Bi4001936  0.798
2013 Park L, Zhou P, Koizumi K, El Jamal S, Previti ML, Van Nostrand WE, Carlson G, Iadecola C. Brain and circulating levels of Aβ1-40 differentially contribute to vasomotor dysfunction in the mouse brain. Stroke; a Journal of Cerebral Circulation. 44: 198-204. PMID 23204056 DOI: 10.1161/Strokeaha.112.670976  0.384
2012 Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice. Journal of Alzheimer's Disease : Jad. 31: 359-69. PMID 22635103 DOI: 10.3233/JAD-2012-120421  0.429
2012 Ladiwala AR, Litt J, Kane RS, Aucoin DS, Smith SO, Ranjan S, Davis J, Van Nostrand WE, Tessier PM. Conformational differences between two amyloid β oligomers of similar size and dissimilar toxicity. The Journal of Biological Chemistry. 287: 24765-73. PMID 22547072 DOI: 10.1074/Jbc.M111.329763  0.502
2012 Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-Degenerative Diseases. 10: 122-6. PMID 22326991 DOI: 10.1159/000334914  0.363
2012 Van Nostrand WE, Davis J, Previti ML, Xu F. Clearance of amyloid-β protein deposits in transgenic mice following focal cerebral ischemia Neurodegenerative Diseases. 10: 108-111. PMID 22269180 DOI: 10.1159/000334763  0.443
2010 Robert R, Lefranc MP, Ghochikyan A, Agadjanyan MG, Cribbs DH, Van Nostrand WE, Wark KL, Dolezal O. Restricted V gene usage and VH/VL pairing of mouse humoral response against the N-terminal immunodominant epitope of the amyloid β peptide. Molecular Immunology. 48: 59-72. PMID 20970857 DOI: 10.1016/j.molimm.2010.09.012  0.392
2010 Van Nostrand WE, Xu F, Rozemuller AJ, Colton CA. Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2. Stroke; a Journal of Cerebral Circulation. 41: S135-8. PMID 20876489 DOI: 10.1161/STROKEAHA.110.595272  0.513
2010 Liao MC, Hoos MD, Aucoin D, Ahmed M, Davis J, Smith SO, Van Nostrand WE. N-terminal domain of myelin basic protein inhibits amyloid beta-protein fibril assembly. The Journal of Biological Chemistry. 285: 35590-8. PMID 20807757 DOI: 10.1074/Jbc.M110.169599  0.801
2010 Ahmed M, Davis J, Aucoin D, Sato T, Ahuja S, Aimoto S, Elliott JI, Van Nostrand WE, Smith SO. Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils. Nature Structural & Molecular Biology. 17: 561-7. PMID 20383142 DOI: 10.1038/Nsmb.1799  0.496
2010 Liao MC, Van Nostrand WE. Degradation of soluble and fibrillar amyloid beta-protein by matrix metalloproteinase (MT1-MMP) in vitro. Biochemistry. 49: 1127-36. PMID 20050683 DOI: 10.1021/bi901994d  0.65
2010 Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-β vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease (The Journal of Neuroscience (2009) (7957-7965)) Journal of Neuroscience. 30: 1197-1198.  0.382
2009 Liao MC, Ahmed M, Smith SO, Van Nostrand WE. Degradation of amyloid beta protein by purified myelin basic protein. The Journal of Biological Chemistry. 284: 28917-25. PMID 19692707 DOI: 10.1074/Jbc.M109.050856  0.778
2009 Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7957-65. PMID 19553436 DOI: 10.1523/JNEUROSCI.1339-09.2009  0.4
2009 Xu F, Previti ML, Nieman MT, Davis J, Schmaier AH, Van Nostrand WE. AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral thrombosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5666-70. PMID 19403832 DOI: 10.1523/JNEUROSCI.0095-09.2009  0.463
2009 Hoos MD, Ahmed M, Smith SO, Van Nostrand WE. Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro. Biochemistry. 48: 4720-7. PMID 19385666 DOI: 10.1021/Bi900037S  0.838
2009 Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nature Cell Biology. 11: 143-53. PMID 19098903 DOI: 10.1038/Ncb1819  0.564
2008 Colton CA, Wilcock DM, Wink DA, Davis J, Van Nostrand WE, Vitek MP. The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP. Journal of Alzheimer's Disease : Jad. 15: 571-87. PMID 19096157 DOI: 10.3233/Jad-2008-15405  0.508
2008 Van Vickle GD, Esh CL, Daugs ID, Kokjohn TA, Kalback WM, Patton RL, Luehrs DC, Walker DG, Lue LF, Beach TG, Davis J, Van Nostrand WE, Castaño EM, Roher AE. Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy. The American Journal of Pathology. 173: 483-93. PMID 18599612 DOI: 10.2353/ajpath.2008.071191  0.575
2008 Xu F, Vitek MP, Colton CA, Previti ML, Gharkholonarehe N, Davis J, Van Nostrand WE. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5312-20. PMID 18480287 DOI: 10.1523/JNEUROSCI.1042-08.2008  0.566
2008 Wilcock DM, Lewis MR, Van Nostrand WE, Davis J, Previti ML, Gharkholonarehe N, Vitek MP, Colton CA. Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1537-45. PMID 18272675 DOI: 10.1523/JNEUROSCI.5066-07.2008  0.417
2007 Vasilevko V, Xu F, Previti ML, Van Nostrand WE, Cribbs DH. Experimental investigation of antibody-mediated clearance mechanisms of amyloid-beta in CNS of Tg-SwDI transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13376-83. PMID 18057195 DOI: 10.1523/JNEUROSCI.2788-07.2007  0.497
2007 Fan R, DeFilippis K, Van Nostrand WE. Induction of complement proteins in a mouse model for cerebral microvascular A beta deposition. Journal of Neuroinflammation. 4: 22. PMID 17877807 DOI: 10.1186/1742-2094-4-22  0.408
2007 Xu F, Previti ML, Van Nostrand WE. Increased severity of hemorrhage in transgenic mice expressing cerebral protease nexin-2/amyloid beta-protein precursor. Stroke; a Journal of Cerebral Circulation. 38: 2598-601. PMID 17656662 DOI: 10.1161/STROKEAHA.106.480103  0.454
2007 Fan R, Xu F, Previti ML, Davis J, Grande AM, Robinson JK, Van Nostrand WE. Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3057-63. PMID 17376966 DOI: 10.1523/Jneurosci.4371-06.2007  0.49
2007 Xu F, Grande AM, Robinson JK, Previti ML, Vasek M, Davis J, Van Nostrand WE. Early-onset subicular microvascular amyloid and neuroinflammation correlate with behavioral deficits in vasculotropic mutant amyloid β-protein precursor transgenic mice Neuroscience. 146: 98-107. PMID 17331655 DOI: 10.1016/J.Neuroscience.2007.01.043  0.429
2007 Hoos MD, Ahmed M, Smith SO, Van Nostrand WE. Inhibition of familial cerebral amyloid angiopathy mutant amyloid beta-protein fibril assembly by myelin basic protein. The Journal of Biological Chemistry. 282: 9952-61. PMID 17259179 DOI: 10.1074/Jbc.M603494200  0.835
2007 Chow N, Bell RD, Deane R, Streb JW, Chen J, Brooks A, Van Nostrand W, Miano JM, Zlokovic BV. Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype. Proceedings of the National Academy of Sciences of the United States of America. 104: 823-8. PMID 17215356 DOI: 10.1073/Pnas.0608251104  0.456
2006 Yamamoto N, Van Nostrand WE, Yanagisawa K. Further evidence of local ganglioside-dependent amyloid beta-protein assembly in brain. Neuroreport. 17: 1735-7. PMID 17047463 DOI: 10.1097/01.wnr.0000239958.53072.14  0.519
2006 Carrasco J, Adlard P, Cotman C, Quintana A, Penkowa M, Xu F, Van Nostrand WE, Hidalgo J. Metallothionein-I and -III expression in animal models of Alzheimer disease. Neuroscience. 143: 911-22. PMID 17027170 DOI: 10.1016/J.Neuroscience.2006.08.054  0.41
2006 Colton CA, Mott RT, Sharpe H, Xu Q, Van Nostrand WE, Vitek MP. Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. Journal of Neuroinflammation. 3: 27. PMID 17005052 DOI: 10.1186/1742-2094-3-27  0.38
2006 Colton CA, Vitek MP, Wink DA, Xu Q, Cantillana V, Previti ML, Van Nostrand WE, Weinberg JB, Weinberg B, Dawson H. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 12867-72. PMID 16908860 DOI: 10.1073/pnas.0601075103  0.566
2006 Burgess BL, McIsaac SA, Naus KE, Chan JY, Tansley GH, Yang J, Miao F, Ross CJ, van Eck M, Hayden MR, van Nostrand W, St George-Hyslop P, Westaway D, Wellington CL. Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma. Neurobiology of Disease. 24: 114-27. PMID 16899370 DOI: 10.1016/J.Nbd.2006.06.007  0.323
2006 Previti ML, Zhang W, Van Nostrand WE. Dexamethasone diminishes the pro-inflammatory and cytotoxic effects of amyloid beta-protein in cerebrovascular smooth muscle cells. Journal of Neuroinflammation. 3: 18. PMID 16887032 DOI: 10.1186/1742-2094-3-18  0.496
2006 Herzig MC, Van Nostrand WE, Jucker M. Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models. Brain Pathology (Zurich, Switzerland). 16: 40-54. PMID 16612981 DOI: 10.1111/j.1750-3639.2006.tb00560.x  0.579
2006 Davis J, Xu F, Miao J, Previti ML, Romanov G, Ziegler K, Van Nostrand WE. Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double A beta in human A betaPP transgenic mice. Neurobiology of Aging. 27: 946-54. PMID 16105708 DOI: 10.1016/j.neurobiolaging.2005.05.031  0.348
2005 Xu F, Davis J, Miao J, Previti ML, Romanov G, Ziegler K, Van Nostrand WE. Protease nexin-2/amyloid beta-protein precursor limits cerebral thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18135-40. PMID 16330760 DOI: 10.1073/pnas.0507798102  0.478
2005 Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease. The Journal of Biological Chemistry. 280: 43243-56. PMID 16207707 DOI: 10.1074/Jbc.M508781200  0.493
2005 Miao J, Xu F, Davis J, Otte-Höller I, Verbeek MM, Van Nostrand WE. Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein. The American Journal of Pathology. 167: 505-15. PMID 16049335  0.584
2005 Miao J, Vitek MP, Xu F, Previti ML, Davis J, Van Nostrand WE. Reducing cerebral microvascular amyloid-beta protein deposition diminishes regional neuroinflammation in vasculotropic mutant amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6271-7. PMID 16000616 DOI: 10.1523/JNEUROSCI.1306-05.2005  0.619
2005 Wilhelmus MM, Otte-Höller I, Davis J, Van Nostrand WE, de Waal RM, Verbeek MM. Apolipoprotein E genotype regulates amyloid-beta cytotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3621-7. PMID 15814793 DOI: 10.1523/JNEUROSCI.4213-04.2005  0.529
2005 Yamamoto N, Hirabayashi Y, Amari M, Yamaguchi H, Romanov G, Van Nostrand WE, Yanagisawa K. Assembly of hereditary amyloid beta-protein variants in the presence of favorable gangliosides. Febs Letters. 579: 2185-90. PMID 15811339 DOI: 10.1016/j.febslet.2005.03.013  0.595
2005 Miao J, Xu F, Davis J, Otte-Höller I, Verbeek MM, Van Nostrand WE. Cerebral microvascular amyloid β protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid β precursor protein American Journal of Pathology. 167: 505-515.  0.529
2004 Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, et al. LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms. Neuron. 43: 333-44. PMID 15294142 DOI: 10.1016/J.Neuron.2004.07.017  0.589
2004 Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, Zlokovic BV, Van Nostrand WE. Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor. The Journal of Biological Chemistry. 279: 20296-306. PMID 14985348 DOI: 10.1074/Jbc.M312946200  0.571
2003 Davis J, Wagner MR, Zhang W, Xu F, Van Nostrand WE. Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells. The Journal of Biological Chemistry. 278: 19054-61. PMID 12754271 DOI: 10.1074/jbc.M301398200  0.425
2003 Jung SS, Zhang W, Van Nostrand WE. Pathogenic A beta induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells. Journal of Neurochemistry. 85: 1208-15. PMID 12753080 DOI: 10.1046/j.1471-4159.2003.01745.x  0.323
2003 Jung SS, Van Nostrand WE. Humanin rescues human cerebrovascular smooth muscle cells from Abeta-induced toxicity. Journal of Neurochemistry. 84: 266-72. PMID 12558989 DOI: 10.1046/j.1471-4159.2003.01524.x  0.495
2002 Van Nostrand WE, Melchor JP, Romanov G, Zeigler K, Davis J. Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor. Annals of the New York Academy of Sciences. 977: 258-65. PMID 12480759 DOI: 10.1111/J.1749-6632.2002.Tb04824.X  0.824
2002 Jung SS, Van Nostrand WE. Abeta does not induce oxidative stress in human cerebrovascular smooth muscle cells. Neuroreport. 13: 1309-12. PMID 12151793  0.417
2002 Van Nostrand WE, Melchor JP, Keane DM, Saporito-Irwin SM, Romanov G, Davis J, Xu F. Localization of a fibrillar amyloid beta-protein binding domain on its precursor. The Journal of Biological Chemistry. 277: 36392-8. PMID 12107175 DOI: 10.1074/jbc.M204676200  0.814
2001 Van Nostrand WE, Melchor JP. Disruption of pathologic amyloid beta-protein fibril assembly on the surface of cultured human cerebrovascular smooth muscle cells. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 8: 20-7. PMID 11676286  0.807
2001 Van Nostrand WE, Melchor JP, Cho HS, Greenberg SM, Rebeck GW. Pathogenic Effects of D23N Iowa Mutant Amyloid β-Protein Journal of Biological Chemistry. 276: 32860-32866. PMID 11441013 DOI: 10.1074/Jbc.M104135200  0.801
2000 Wagner MR, Keane DM, Melchor JP, Auspaker KR, Van Nostrand WE. Fibrillar amyloid beta-protein binds protease nexin-2/amyloid beta-protein precursor: stimulation of its inhibition of coagulation factor XIa. Biochemistry. 39: 7420-7. PMID 10858290 DOI: 10.1021/bi0002840  0.821
2000 Verbeek MM, Van Nostrand WE, Otte-Höller I, Wesseling P, De Waal RMW. Amyloid-β-induced degeneration of human brain pericytes is dependent on the apolipoprotein E genotype Annals of the New York Academy of Sciences. 903: 187-199. PMID 10818507 DOI: 10.1111/j.1749-6632.2000.tb06368.x  0.463
2000 Van Nostrand WE, Melchor J, Wagner M, Davis J. Cerebrovascular smooth muscle cell surface fibrillar aβ Annals of the New York Academy of Sciences. 903: 89-96. PMID 10818493 DOI: 10.1111/J.1749-6632.2000.Tb06354.X  0.78
2000 Melchor JP, McVoy L, Van Nostrand WE. Charge alterations of E22 enhance the pathogenic properties of the amyloid beta-protein. Journal of Neurochemistry. 74: 2209-12. PMID 10800967 DOI: 10.1046/J.1471-4159.2000.0742209.X  0.813
2000 Melchor JP, Van Nostrand WE. Fibrillar amyloid beta-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells. The Journal of Biological Chemistry. 275: 9782-91. PMID 10734132 DOI: 10.1074/Jbc.275.13.9782  0.807
1999 Davis J, Cribbs DH, Cotman CW, Van Nostrand WE. Pathogenic amyloid beta-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 6: 157-64. PMID 10524279 DOI: 10.3109/13506129909007321  0.402
1999 Van Nostrand WE, Porter M. Plasmin cleavage of the amyloid β-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity Biochemistry. 38: 11570-11576. PMID 10471309 DOI: 10.1021/bi990610f  0.473
1998 Van Nostrand WE, Melchor JP, Ruffini L. Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cells. Journal of Neurochemistry. 70: 216-23. PMID 9422365 DOI: 10.1046/J.1471-4159.1998.70010216.X  0.734
1997 Verbeek MM, De Waal RMW, Schipper JJ, Van Nostrand WE. Rapid degeneration of cultured human brain pericytes by amyloid β protein Journal of Neurochemistry. 68: 1135-1141. PMID 9048759  0.51
1997 Verbeek MM, De Waal RMW, Van Nostrand WE. Aβ-induced cytotoxicity: A model for cerebral vascular degeneration in Alzheimer's disease Endothelium: Journal of Endothelial Cell Research. 5: 355.  0.339
1997 Saporito-Irwin SM, Thinakaran G, Ruffini L, Sisodia SS, Van Nostrand WE. Amyloid ß-protein stimulates parallel increases in cellular levels of its precursor and amyloid precursor-like protein 2 (APLP2) in human cerebrovascular smooth muscle cells Amyloid. 4: 54-60.  0.46
1996 Van Nostrand WE, Davis-Salinas J, Saporito-Irwin SM. Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders Annals of the New York Academy of Sciences. 777: 297-302. PMID 8624102  0.522
1996 Davis J, Van Nostrand WE. Enhanced pathologic properties of Dutch-type mutant amyloid β-protein Proceedings of the National Academy of Sciences of the United States of America. 93: 2996-3000. PMID 8610157 DOI: 10.1073/pnas.93.7.2996  0.54
1995 Choi BH, Kim RC, Vaughan PJ, Lau A, Van Nostrand WE, Cotman CW, Cunningham DD. Decreases in protease nexins in Alzheimer's disease brain. Neurobiology of Aging. 16: 557-62. PMID 8544905 DOI: 10.1016/0197-4580(95)00060-R  0.405
1995 Van Nostrand WE. Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid β-Protein precursor Thrombosis Research. 78: 43-53. PMID 7778065 DOI: 10.1016/0049-3848(95)00033-X  0.317
1995 Davis-Salinas J, Van Nostrand WE. Amyloid β-protein aggregation nullifies its pathologic properties in cultured cerebrovascular smooth muscle cells Journal of Biological Chemistry. 270: 20887-20890. PMID 7673109 DOI: 10.1074/jbc.270.36.20887  0.528
1995 Veerhuis R, van der Valk P, Janssen I, Zhan SS, Eikelenboom P, Van Nostrand WE. Complement activation in amyloid plaques in Alzheimer's disease brains does not proceed further than C3 Virchows Archiv. 426: 603-610. PMID 7655742 DOI: 10.1007/Bf00192116  0.351
1995 Gregori L, Fuchs C, Figueiredo-Pereira ME, Van Nostrand WE, Goldgaber D. Amyloid β-protein inhibits ubiquitin-dependent protein degradation in vitro Journal of Biological Chemistry. 270: 19702-19708. PMID 7649980 DOI: 10.1074/jbc.270.34.19702  0.493
1995 Davis-Salinas J, Saporito-Irwin SM, Cotman CW, Van Nostrand WE. Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. Journal of Neurochemistry. 65: 931-4. PMID 7616257 DOI: 10.1046/J.1471-4159.1995.65020931.X  0.343
1995 Zhan SS, Kamphorst W, Van Nostrand WE, Eikelenboom P. Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly Acta Neuropathologica. 89: 356-362. PMID 7610767 DOI: 10.1007/Bf00309629  0.416
1995 Saporito-Irwin SM, Van Nostrand WE. Coagulation factor XIa cleaves the RHDS sequence and abolishes the cell adhesive properties of the amyloid β-protein Journal of Biological Chemistry. 270: 26265-26269. PMID 7592834 DOI: 10.1074/jbc.270.44.26265  0.482
1994 Davis-Salinas J, Saporito-Irwin SM, Donovan FM, Cunningham DD, Van Nostrand WE. Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor. The Journal of Biological Chemistry. 269: 22623-7. PMID 8077213  0.328
1994 Van Nostrand WE, Schmaier AH, Neiditch BR, Siegel RS, Raschke WC, Sisodia SS, Wagner SL. Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2. Biochimica Et Biophysica Acta. 1209: 165-70. PMID 7811686 DOI: 10.1016/0167-4838(94)90180-5  0.324
1993 Kibbey MC, Jucker M, Weeks BS, Neve RL, Van Nostrand WE, Kleinman HK. β-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin Proceedings of the National Academy of Sciences of the United States of America. 90: 10150-10153. PMID 8234269 DOI: 10.1073/pnas.90.21.10150  0.452
1993 Rozemuller AJM, Roos RAC, Bots GTAM, Kamphorst W, Eikelenboom P, Van Nostrand WE. Distribution of β/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease American Journal of Pathology. 142: 1449-1457. PMID 7684195  0.478
1992 van Nostrand WE, Wagner SL, Haan J, Bakker E, Roos RAC. Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis–dutch type share a decrease in cerebrospinal fluid levels of amyloid β‐protein precursor Annals of Neurology. 32: 215-218. PMID 1510361 DOI: 10.1002/ana.410320214  0.425
1992 Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 48: 763-77. PMID 1378573 DOI: 10.1016/0306-4522(92)90265-4  0.524
1992 Farlow M, Ghetti B, Benson MD, Farrow JS, van Nostrand WE, Wagner SL. Low cerebrospinal-fluid concentrations of soluble amyloid beta-protein precursor in hereditary Alzheimer's disease. Lancet. 340: 453-4. PMID 1354785 DOI: 10.1016/0140-6736(92)91771-Y  0.439
1992 VAN NOSTRAND WE, SCHMAIER AH, WAGNER SL. Potential Role of Protease Nexin‐2/Amyloid β‐Protein Precursor as a Cerebral Anticoagulant Annals of the New York Academy of Sciences. 674: 243-252. PMID 1288367 DOI: 10.1111/j.1749-6632.1992.tb27493.x  0.462
1991 Abraham CR, Driscoll J, Potter H, Van Nostrand WE, Tempst P. A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid beta-protein. Biochemical and Biophysical Research Communications. 174: 790-6. PMID 1993072 DOI: 10.1016/0006-291X(91)91487-W  0.437
1991 Bhasin R, Van Nostrand WE, Saitoh T, Donets MA, Barnes EA, Quitschke WW, Goldgaber D. Expression of active secreted forms of human amyloid beta-protein precursor by recombinant baculovirus-infected insect cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10307-11. PMID 1946449  0.451
1991 Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD. The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proceedings of the National Academy of Sciences of the United States of America. 88: 10302-6. PMID 1946448 DOI: 10.1073/Pnas.88.22.10302  0.458
1991 Van Nostrand WE, Schmaier AH, Farrow JS, Cines DB, Cunningham DD. Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochemical and Biophysical Research Communications. 175: 15-21. PMID 1900151 DOI: 10.1016/S0006-291X(05)81193-3  0.377
1991 Abraham CR, Razzaboni BL, Sisodia SS, Koo EH, Price DL, Van Nostrand WE, Papastoitsis G. Studies on the proteolytic degradation of the beta-protein precursor by proteases purified from Alzheimer's disease brain. Annals of the New York Academy of Sciences. 640: 161-5. PMID 1776735 DOI: 10.1111/J.1749-6632.1991.Tb00209.X  0.413
1991 Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Platelet protease nexin-2/amyloid beta-protein precursor. Possible pathologic and physiologic functions. Annals of the New York Academy of Sciences. 640: 140-4. PMID 1776731 DOI: 10.1111/J.1749-6632.1991.Tb00205.X  0.5
1990 Van Nostrand WE, Wagner SL, Farrow JS, Cunningham DD. Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor. The Journal of Biological Chemistry. 265: 9591-4. PMID 2112543  0.397
1990 Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein. Science (New York, N.Y.). 248: 745-8. PMID 2110384 DOI: 10.1126/Science.2110384  0.359
1989 Van Nostrand WE, Wagner SL, Suzuki M, Choi BH, Farrow JS, Geddes JW, Cotman CW, Cunningham DD. Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature. 341: 546-9. PMID 2507928 DOI: 10.1038/341546A0  0.39
Low-probability matches (unlikely to be authored by this person)
2020 Lee H, Xu F, Liu X, Koundal S, Zhu X, Davis J, Yanez D, Schrader J, Stanisavljevic A, Rothman DL, Wardlaw J, Van Nostrand WE, Benveniste H. Diffuse white matter loss in a transgenic rat model of cerebral amyloid angiopathy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20944226. PMID 32791876 DOI: 10.1177/0271678X20944226  0.299
1993 Wagner SL, Van Nostrand WE, Lau AL, Farrow JS, Suzuki M, Bartus RT, Schuppek R, Nguyen A, Cotman CW, Cunningham DD. Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Research. 626: 90-8. PMID 8281456 DOI: 10.1016/0006-8993(93)90567-7  0.287
2021 Schrader JM, Xu F, Lee H, Barlock B, Benveniste H, Van Nostrand WE. Emergent White Matter Degeneration in the rTg-DI Rat Model of Cerebral Amyloid Angiopathy Exhibits Unique Proteomic Changes. The American Journal of Pathology. PMID 34896071 DOI: 10.1016/j.ajpath.2021.11.010  0.279
2022 Schrader JM, Stanisavljevic A, Xu F, Van Nostrand WE. Distinct Brain Proteomic Signatures in Cerebral Small Vessel Disease Rat Models of Hypertension and Cerebral Amyloid Angiopathy. Journal of Neuropathology and Experimental Neurology. PMID 35856898 DOI: 10.1093/jnen/nlac057  0.276
1995 Van Nostrand WE, Schmaier AH, Siegel RS, Wagner SL, Raschke WC. Enhanced plasmin inhibition by a reactive center lysine mutant of the Kunitz-type protease inhibitor domain of the amyloid β-protein precursor Journal of Biological Chemistry. 270: 22827-22830. PMID 7559414 DOI: 10.1074/jbc.270.39.22827  0.267
1992 Wagner SL, Siegel RS, Vedvick TS, Raschke WC, Van Nostrand WE. High level expression, purification, and characterization of the Kunitz-type protease inhibitor domain of protease nexin-2/amyloid β-protein precursor Biochemical and Biophysical Research Communications. 186: 1138-1145. PMID 1497647 DOI: 10.1016/0006-291X(92)90865-I  0.265
1993 Schmaier AH, Dahl LD, Rozemuller AJM, Roos RAC, Wagner SL, Chung R, Van Nostrand WE. Protease nexin-2/amyloid β protein precursor. A tight-binding inhibitor of coagulation factor IXa Journal of Clinical Investigation. 92: 2540-2545. PMID 8227367  0.257
1995 Mahdi F, Van Nostrand WE, Schmaier AH. Protease nexin-2/amyloid β-protein precursor inhibits factor Xa in the prothrombinase complex Journal of Biological Chemistry. 270: 23468-23474. PMID 7559509 DOI: 10.1074/jbc.270.40.23468  0.253
1997 Scandura JM, Zhang Y, Van Nostrand WE, Walsh PN. Progress curve analysis of the kinetics with which blood coagulation factor XIa is inhibited by protease nexin-2. Biochemistry. 36: 412-20. PMID 9003194 DOI: 10.1021/bi9612576  0.252
2019 Francis N, Robison LS, Popescu DL, Michaelos M, Hatfield J, Xu F, Zhu X, Davis J, Anderson ME, Anderson BJ, Van Nostrand WE, Robinson JK. Voluntary Wheel Running Reduces Amyloid-β42 and Rescues Behavior in Aged Tg2576 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31796673 DOI: 10.3233/Jad-190810  0.249
1995 Verbeek MM, Otte-Höller I, Wesseling P, Van Nostrand WE, Sorg C, de Waal RMW, Ruiter DJ. A lysosomal marker for activated microglial cells involved in Alzheimer classic senile plaques Acta Neuropathologica. 90: 493-503. PMID 8560983 DOI: 10.1007/BF00294811  0.249
1998 Bornebroek M, Von Dem Borne PAK, Haan J, Meijers JCM, Van Nostrand WE, Roos RAC. Binding of amyloid β precursor protein to coagulation factor XIa in vivo may favour haemorrhagic stroke Journal of Neurology. 245: 111-115. PMID 9507418 DOI: 10.1007/s004150050188  0.237
2022 Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand WE, Benveniste H. Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Nature Aging. 2: 214-223. PMID 36199752 DOI: 10.1038/s43587-022-00181-4  0.227
2023 Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand WE, Benveniste H. Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Nature Aging. PMID 38001312 DOI: 10.1038/s43587-023-00544-5  0.223
2023 Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand WE, Benveniste H. Publisher Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Nature Aging. 2: 454. PMID 37118076 DOI: 10.1038/s43587-022-00223-x  0.223
2017 Lewczuk P, Riederer P, O'Bryant SE, Verbeek MM, Dubois B, Visser PJ, Jellinger KA, Engelborghs S, Ramirez A, Parnetti L, Jack CR, Teunissen CE, Hampel H, Lleó A, Jessen F, ... ... Van Nostrand WE, et al. Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-85. PMID 29076399 DOI: 10.1080/15622975.2017.1375556  0.22
1994 Van Nostrand WE, Rozemuller AJM, Chung R, Cotman CW, Saporito-Irwin SM. Amyloid βprotein precursor in cultured leptomeningeal smooth muscle cells Amyloid. 1: 1-7. DOI: 10.3109/13506129409148618  0.214
1986 Farrell DH, Van Nostrand WE, Cunningham DD. A simple two-step purification of protease nexin. The Biochemical Journal. 237: 907-12. PMID 3099760 DOI: 10.1042/Bj2370907  0.213
2011 Park L, Wang G, Zhou P, Zhou J, Pitstick R, Previti ML, Younkin L, Younkin SG, Van Nostrand WE, Cho S, Anrather J, Carlson GA, Iadecola C. Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta. Proceedings of the National Academy of Sciences of the United States of America. 108: 5063-8. PMID 21383152 DOI: 10.1073/Pnas.1015413108  0.211
2011 Blackshear AL, Xu W, Anderson M, Xu F, Previti ML, Van Nostrand WE, Robinson JK. A novel operant testing regimen for multi-construct cognitive characterization of a murine model of Alzheimer's amyloid-related behavioral impairment. Neurobiology of Learning and Memory. 96: 443-51. PMID 21763776 DOI: 10.1016/J.Nlm.2011.06.017  0.204
1986 Cunningham DD, Van Nostrand WE, Farrell DH, Campbell CH. Interactions of serine proteases with cultured fibroblasts. Journal of Cellular Biochemistry. 32: 281-91. PMID 3543029 DOI: 10.1002/Jcb.240320405  0.198
2013 Bourassa MW, Leskovjan AC, Tappero RV, Farquhar ER, Colton CA, Van Nostrand WE, Miller LM. Elevated copper in the amyloid plaques and iron in the cortex are observed in mouse models of Alzheimer's disease that exhibit neurodegeneration. Biomedical Spectroscopy and Imaging. 2: 129-139. PMID 24926425 DOI: 10.3233/Bsi-130041  0.194
1988 Wagner SL, Van Nostrand WE, Lau AL, Cunningham DD. Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases. Biochemistry. 27: 2173-6. PMID 3378052 DOI: 10.1021/Bi00406A053  0.163
2000 Mahdi F, Rehemtulla A, Van Nostrand WE, Bajaj SP, Schmaier AH. Protease nexin-2/amyloid β-protein precursor regulates factor VIIa and the factor VIIa-tissue factor complex Thrombosis Research. 99: 267-276. PMID 10942793 DOI: 10.1016/S0049-3848(00)00245-0  0.151
1988 Van Nostrand WE, Wagner SL, Cunningham DD. Purification of a form of protease nexin 1 that binds heparin with a low affinity. Biochemistry. 27: 2176-81. PMID 3378053 DOI: 10.1021/Bi00406A054  0.149
2022 Monte B, Constantinou S, Koundal S, Lee H, Dai F, Gursky Z, Van Nostrand WE, Darbinyan A, Zlokovic BV, Wardlaw J, Benveniste H. Characterization of perivascular space pathology in a rat model of cerebral small vessel disease by magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221105668. PMID 35673963 DOI: 10.1177/0271678X221105668  0.139
1987 Van Nostrand WE, Cunningham DD. Purification of a proteinase inhibitor from bovine serum with C1-inhibitor activity. Biochimica Et Biophysica Acta. 923: 167-75. PMID 3814612 DOI: 10.1016/0304-4165(87)90001-8  0.137
1987 Van Nostrand WE, Cunningham DD. Purification of protease nexin II from human fibroblasts. The Journal of Biological Chemistry. 262: 8508-14. PMID 3597385  0.137
2000 Van Nostrand WE. Cellular and transgenic animal models of cerebrovascular amyloidosis Molecular Medicine Today. 6: 373-374. PMID 10954871 DOI: 10.1016/S1357-4310(00)01762-7  0.134
1988 Van Nostrand WE, McKay LD, Baker JB, Cunningham DD. Functional and structural similarities between protease nexin I and C1 inhibitor. The Journal of Biological Chemistry. 263: 3979-83. PMID 3279027  0.133
1997 Zhang Y, Scandura JM, Van Nostrand WE, Walsh PN. The mechanism by which heparin promotes the inhibition of coagulation factor XIa by protease nexin-2. The Journal of Biological Chemistry. 272: 26139-44. PMID 9334179 DOI: 10.1074/jbc.272.42.26139  0.128
2020 Kounda S, Elkin R, Nadeem S, Xue Y, Constantinou S, Sanggaard S, Liu X, Monte B, Xu F, Van Nostrand W, Nedergaard M, Lee H, Wardlaw J, Benveniste H, Tannenbaum A. Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System. Scientific Reports. 10: 1990. PMID 32029859 DOI: 10.1038/S41598-020-59045-9  0.09
1985 Van Nostrand WE, Cunningham DD. Purification of a protease nexin II-like inhibitor from bovine serum Federation Proceedings. 44.  0.058
2018 Robison LS, Popescu DL, Anderson ME, Beigelman SI, Fitzgerald SM, Kuzmina AE, Lituma DA, Subzwari S, Michaelos M, Anderson BJ, Van Nostrand WE, Robinson JK. The effects of volume versus intensity of long-term voluntary exercise on physiology and behavior in C57/Bl6 mice. Physiology & Behavior. PMID 29879399 DOI: 10.1016/J.Physbeh.2018.06.002  0.046
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