| Year |
Citation |
Score |
| 2024 |
Daniels AJ, McDade E, Llibre-Guerra JJ, Xiong C, Perrin RJ, Ibanez L, Supnet-Bell C, Cruchaga C, Goate A, Renton AE, Benzinger TLS, Gordon BA, Hassenstab J, Karch C, Popp B, ... ... Jucker M, et al. 15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in DIAN. Medrxiv : the Preprint Server For Health Sciences. PMID 39148846 DOI: 10.1101/2024.08.08.24311689 |
0.415 |
|
| 2024 |
Kim B, Dabin LC, Tate MD, Karahan H, Sharify AD, Acri DJ, Al-Amin MM, Philtjens S, Smith DC, Wijeratne HRS, Park JH, Jucker M, Kim J. Effects of SPI1-mediated transcriptome remodeling on Alzheimer's disease-related phenotypes in mouse models of Aβ amyloidosis. Nature Communications. 15: 3996. PMID 38734693 DOI: 10.1038/s41467-024-48484-x |
0.383 |
|
| 2024 |
Levin J, Baiardi S, Quadalti C, Rossi M, Mammana A, Vöglein J, Bernhardt A, Perrin RJ, Jucker M, Preische O, Hofmann A, Höglinger GU, Cairns NJ, Franklin EE, Chrem P, et al. α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38666355 DOI: 10.1002/alz.13818 |
0.398 |
|
| 2024 |
Parvin F, Haglund S, Wegenast-Braun B, Jucker M, Saito T, Saido TC, Nilsson KPR, Nilsson P, Nyström S, Hammarström P. Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and Mice. Acs Chemical Neuroscience. PMID 38652895 DOI: 10.1021/acschemneuro.4c00104 |
0.416 |
|
| 2024 |
Wisch JK, McKay NS, Boerwinkle AH, Kennedy J, Flores S, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, O'Bryant SE, Price JC, Laymon CM, Krinsky-McHale SJ, Lai F, ... ... Jucker M, et al. Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study. The Lancet. Neurology. 23: 500-510. PMID 38631766 DOI: 10.1016/S1474-4422(24)00084-X |
0.324 |
|
| 2023 |
Millar PR, Gordon BA, Wisch JK, Schultz SA, Benzinger TL, Cruchaga C, Hassenstab JJ, Ibanez L, Karch C, Llibre-Guerra JJ, Morris JC, Perrin RJ, Supnet-Bell C, Xiong C, Allegri RF, ... ... Jucker M, et al. Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease. Molecular Neurodegeneration. 18: 98. PMID 38111006 DOI: 10.1186/s13024-023-00688-3 |
0.419 |
|
| 2023 |
Tu JC, Millar PR, Strain JF, Eck A, Adeyemo B, Daniels A, Karch C, Huey ED, McDade E, Day GS, Yakushev I, Hassenstab J, Morris J, Llibre-Guerra JJ, Ibanez L, ... Jucker M, et al. Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease. Biorxiv : the Preprint Server For Biology. PMID 37961586 DOI: 10.1101/2023.10.29.564633 |
0.409 |
|
| 2023 |
Jucker M, Walker LC. Alzheimer's disease: From immunotherapy to immunoprevention. Cell. 186: 4260-4270. PMID 37729908 DOI: 10.1016/j.cell.2023.08.021 |
0.318 |
|
| 2023 |
Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, ... ... Jucker M, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature Medicine. PMID 37550416 DOI: 10.1038/s41591-023-02476-4 |
0.404 |
|
| 2023 |
Lerouge F, Ong E, Rositi H, Mpambani F, Berner LP, Bolbos R, Olivier C, Peyrin F, Apputukan VK, Monnereau C, Andraud C, Chaput F, Berthezène Y, Braun B, Jucker M, et al. targeting and multimodal imaging of cerebral amyloid-β aggregates using hybrid GdF nanoparticles. Nanomedicine (London, England). PMID 36927004 DOI: 10.2217/nnm-2022-0252 |
0.385 |
|
| 2023 |
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, Häsler LM, McManus R, Ising C, Röske S, Peters O, Cosma NC, Schneider LS, Wang X, ... ... Jucker M, et al. Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study. Alzheimer's Research & Therapy. 15: 13. PMID 36631909 DOI: 10.1186/s13195-022-01118-0 |
0.368 |
|
| 2022 |
Rother C, Uhlmann RE, Müller SA, Schelle J, Skodras A, Obermüller U, Häsler LM, Lambert M, Baumann F, Xu Y, Bergmann C, Salvadori G, Loos M, Brzak I, Shimshek D, ... ... Jucker M, et al. Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae. Nature Communications. 13: 7333. PMID 36443293 DOI: 10.1038/s41467-022-34538-5 |
0.522 |
|
| 2022 |
Wagner J, Degenhardt K, Veit M, Louros N, Konstantoulea K, Skodras A, Wild K, Liu P, Obermüller U, Bansal V, Dalmia A, Häsler LM, Lambert M, De Vleeschouwer M, Davies HA, ... ... Jucker M, et al. Medin co-aggregates with vascular amyloid-β in Alzheimer's disease. Nature. PMID 36385530 DOI: 10.1038/s41586-022-05440-3 |
0.46 |
|
| 2022 |
Eninger T, Müller SA, Bacioglu M, Schweighauser M, Lambert M, Maia LF, Neher JJ, Hornfeck SM, Obermüller U, Kleinberger G, Haass C, Kahle PJ, Staufenbiel M, Ping L, Duong DM, ... ... Jucker M, et al. Signatures of glial activity can be detected in the CSF proteome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119804119. PMID 35666874 DOI: 10.1073/pnas.2119804119 |
0.317 |
|
| 2022 |
Morris JC, Weiner M, Xiong C, Beckett L, Coble D, Saito N, Aisen PS, Allegri R, Benzinger TLS, Berman SB, Cairns NJ, Carrillo MC, Chui HC, Chhatwal JP, Cruchaga C, ... ... Jucker M, et al. Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. Brain : a Journal of Neurology. PMID 35580594 DOI: 10.1093/brain/awac181 |
0.372 |
|
| 2022 |
Millar PR, Luckett PH, Gordon BA, Benzinger TL, Schindler SE, Fagan AM, Cruchaga C, Bateman RJ, Allegri R, Jucker M, Lee JH, Mori H, Salloway SP, Yakushev I, Morris JC, et al. Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease. Neuroimage. 119228. PMID 35452806 DOI: 10.1016/j.neuroimage.2022.119228 |
0.411 |
|
| 2022 |
Morenas-Rodríguez E, Li Y, Nuscher B, Franzmeier N, Xiong C, Suárez-Calvet M, Fagan AM, Schultz S, Gordon BA, Benzinger TLS, Hassenstab J, McDade E, Feederle R, Karch CM, Schlepckow K, ... ... Jucker M, et al. Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study. The Lancet. Neurology. 21: 329-341. PMID 35305339 DOI: 10.1016/S1474-4422(22)00027-8 |
0.349 |
|
| 2021 |
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, González PG, McManus RM, Ising C, Santarelli F, Kolbe CC, Häsler LM, Wolfsgruber S, Marquié M, Boada M, Orellana A, de Rojas I, ... ... Jucker M, et al. Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. PMID 34995486 DOI: 10.1016/j.neuron.2021.12.016 |
0.319 |
|
| 2021 |
Gonneaud J, Baria AT, Pichet Binette A, Gordon BA, Chhatwal JP, Cruchaga C, Jucker M, Levin J, Salloway S, Farlow M, Gauthier S, Benzinger TLS, Morris JC, Bateman RJ, Breitner JCS, et al. Accelerated functional brain aging in pre-clinical familial Alzheimer's disease. Nature Communications. 12: 5346. PMID 34504080 DOI: 10.1038/s41467-021-25492-9 |
0.431 |
|
| 2021 |
Barth M, Bacioglu M, Schwarz N, Novotny R, Brandes J, Welzer M, Mazzitelli S, Häsler LM, Schweighauser M, Wuttke TV, Kronenberg-Versteeg D, Fog K, Ambjørn M, Alik A, Melki R, ... ... Jucker M, et al. Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures. Molecular Neurodegeneration. 16: 54. PMID 34380535 DOI: 10.1186/s13024-021-00471-2 |
0.344 |
|
| 2021 |
Emmenegger M, De Cecco E, Hruska-Plochan M, Eninger T, Schneider MM, Barth M, Tantardini E, de Rossi P, Bacioglu M, Langston RG, Kaganovich A, Bengoa-Vergniory N, Gonzalez-Guerra A, Avar M, Heinzer D, ... ... Jucker M, et al. LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies. Embo Molecular Medicine. e14745. PMID 34309222 DOI: 10.15252/emmm.202114745 |
0.319 |
|
| 2021 |
Keret O, Staffaroni AM, Ringman JM, Cobigo Y, Goh SM, Wolf A, Allen IE, Salloway S, Chhatwal J, Brickman AM, Reyes-Dumeyer D, Bateman RJ, Benzinger TLS, Morris JC, Ances BM, ... ... Jucker M, et al. Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12197. PMID 34258377 DOI: 10.1002/dad2.12197 |
0.318 |
|
| 2020 |
Uhlmann RE, Rother C, Rasmussen J, Schelle J, Bergmann C, Ullrich Gavilanes EM, Fritschi SK, Buehler A, Baumann F, Skodras A, Al-Shaana R, Beschorner N, Ye L, Kaeser SA, Obermüller U, ... ... Jucker M, et al. Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life. Nature Neuroscience. PMID 33199898 DOI: 10.1038/s41593-020-00737-w |
0.504 |
|
| 2020 |
Lauwers E, Lalli G, Brandner S, Collinge J, Compernolle V, Duyckaerts C, Edgren G, Haïk S, Hardy J, Helmy A, Ivinson AJ, Jaunmuktane Z, Jucker M, Knight R, Lemmens R, et al. Potential human transmission of amyloid β pathology: surveillance and risks. The Lancet. Neurology. 19: 872-878. PMID 32949547 DOI: 10.1016/S1474-4422(20)30238-6 |
0.435 |
|
| 2020 |
Degenhardt K, Wagner J, Skodras A, Candlish M, Koppelmann AJ, Wild K, Maxwell R, Rotermund C, von Zweydorf F, Gloeckner CJ, Davies HA, Madine J, Del Turco D, Feederle R, Lashley T, ... ... Jucker M, et al. Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32900929 DOI: 10.1073/pnas.2011133117 |
0.351 |
|
| 2020 |
Tanriöver G, Bacioglu M, Schweighauser M, Mahler J, Wegenast-Braun BM, Skodras A, Obermüller U, Barth M, Kronenberg-Versteeg D, Nilsson KPR, Shimshek DR, Kahle PJ, Eisele YS, Jucker M. Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions. Acta Neuropathologica Communications. 8: 133. PMID 32787922 DOI: 10.1186/s40478-020-00993-8 |
0.347 |
|
| 2020 |
Barthélemy NR, Li Y, Joseph-Mathurin N, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Perrin RJ, Goate AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, ... ... Jucker M, et al. A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease. Nature Medicine. 26: 398-407. PMID 32161412 DOI: 10.1038/S41591-020-0781-Z |
0.331 |
|
| 2019 |
Llibre-Guerra JJ, Li Y, Schindler SE, Gordon BA, Fagan AM, Morris JC, Benzinger TLS, Hassenstab J, Wang G, Allegri R, Berman SB, Chhatwal J, Farlow MR, Holtzman DM, Jucker M, et al. Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease. Jama Network Open. 2: e1917126. PMID 31825500 DOI: 10.1001/jamanetworkopen.2019.17126 |
0.323 |
|
| 2019 |
Kollmer M, Close W, Funk L, Rasmussen J, Bsoul A, Schierhorn A, Schmidt M, Sigurdson CJ, Jucker M, Fändrich M. Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue. Nature Communications. 10: 4760. PMID 31664019 DOI: 10.1038/S41467-019-12683-8 |
0.461 |
|
| 2019 |
Fornari S, Schäfer A, Jucker M, Goriely A, Kuhl E. Prion-like spreading of Alzheimer's disease within the brain's connectome. Journal of the Royal Society, Interface. 16: 20190356. PMID 31615329 DOI: 10.1098/Rsif.2019.0356 |
0.371 |
|
| 2019 |
Schelle J, Wegenast‐Braun BM, Fritschi SK, Kaeser SA, Jährling N, Eicke D, Skodras A, Beschorner N, Obermueller U, Häsler LM, Wolfer DP, Mueggler T, Shimshek DR, Neumann U, Dodt H, ... ... Jucker M, et al. Early Aβ reduction prevents progression of cerebral amyloid angiopathy Annals of Neurology. 86: 561-571. PMID 31359452 DOI: 10.1002/Ana.25562 |
0.468 |
|
| 2018 |
Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, ... ... Jucker M, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. Embo Molecular Medicine. PMID 30482868 DOI: 10.15252/Emmm.201809712 |
0.341 |
|
| 2018 |
Rasmussen J, Krasemann S, Altmeppen H, Schwarz P, Schelle J, Aguzzi A, Glatzel M, Jucker M. Infectious prions do not induce Aβ deposition in an in vivo seeding model. Acta Neuropathologica. PMID 29663066 DOI: 10.1007/S00401-018-1848-5 |
0.362 |
|
| 2017 |
Rasmussen J, Mahler J, Beschorner N, Kaeser SA, Häsler LM, Baumann F, Nyström S, Portelius E, Blennow K, Lashley T, Fox NC, Sepulveda-Falla D, Glatzel M, Oblak AL, Ghetti B, ... ... Jucker M, et al. Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158413 DOI: 10.1073/Pnas.1713215114 |
0.445 |
|
| 2017 |
Füger P, Hefendehl JK, Veeraraghavalu K, Wendeln AC, Schlosser C, Obermüller U, Wegenast-Braun BM, Neher JJ, Martus P, Kohsaka S, Thunemann M, Feil R, Sisodia SS, Skodras A, Jucker M. Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging. Nature Neuroscience. PMID 28846081 DOI: 10.1038/Nn.4631 |
0.512 |
|
| 2017 |
Ye L, Rasmussen J, Kaeser SA, Marzesco AM, Obermüller U, Mahler J, Schelle J, Odenthal J, Krüger C, Fritschi SK, Walker LC, Staufenbiel M, Baumann F, Jucker M. Aβ seeding potency peaks in the early stages of cerebral β-amyloidosis. Embo Reports. PMID 28701326 DOI: 10.15252/embr.201744067 |
0.534 |
|
| 2017 |
Rasmussen J, Jucker M, Walker LC. Aβ Seeds and Prions: How Close the Fit? Prion. 0. PMID 28657440 DOI: 10.1080/19336896.2017.1334029 |
0.303 |
|
| 2017 |
Walker LC, Jucker M. The Exceptional Vulnerability of Humans to Alzheimer's Disease. Trends in Molecular Medicine. PMID 28483344 DOI: 10.1016/J.Molmed.2017.04.001 |
0.402 |
|
| 2016 |
Schelle J, Häsler L, Göpfert JC, Joos TO, Vanderstichele H, Stoops E, Mandelkow EM, Neumann U, Shimshek DR, Staufenbiel M, Jucker M, Kaeser SA. Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27750032 DOI: 10.1016/j.jalz.2016.09.005 |
0.418 |
|
| 2016 |
Walker LC, Jucker M. The Malignant Protein Puzzle. Cerebrum : the Dana Forum On Brain Science. 2016. PMID 27408676 |
0.427 |
|
| 2016 |
Marzesco AM, Flötenmeyer M, Bühler A, Obermüller U, Staufenbiel M, Jucker M, Baumann F. Highly potent intracellular membrane-associated Aβ seeds. Scientific Reports. 6: 28125. PMID 27311744 DOI: 10.1038/srep28125 |
0.397 |
|
| 2016 |
Bacioglu M, Maia LF, Preische O, Schelle J, Apel A, Kaeser SA, Schweighauser M, Eninger T, Lambert M, Pilotto A, Shimshek DR, Neumann U, Kahle PJ, Staufenbiel M, Neumann M, ... ... Jucker M, et al. Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases. Neuron. PMID 27292537 DOI: 10.1016/j.neuron.2016.05.018 |
0.326 |
|
| 2016 |
Walker LC, Schelle J, Jucker M. The Prion-Like Properties of Amyloid-β Assemblies: Implications for Alzheimer's Disease. Cold Spring Harbor Perspectives in Medicine. PMID 27270558 DOI: 10.1101/Cshperspect.A024398 |
0.466 |
|
| 2016 |
Novotny R, Langer F, Mahler J, Skodras A, Vlachos A, Wegenast-Braun BM, Kaeser SA, Neher JJ, Eisele YS, Pietrowski MJ, Nilsson KP, Deller T, Staufenbiel M, Heimrich B, Jucker M. Conversion of Synthetic Aβ to In Vivo Active Seeds and Amyloid Plaque Formation in a Hippocampal Slice Culture Model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5084-93. PMID 27147660 DOI: 10.1523/Jneurosci.0258-16.2016 |
0.543 |
|
| 2016 |
Shimshek DR, Jacobson LH, Kolly C, Zamurovic N, Balavenkatraman KK, Morawiec L, Kreutzer R, Schelle J, Jucker M, Bertschi B, Theil D, Heier A, Bigot K, Beltz K, Machauer R, et al. Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice. Scientific Reports. 6: 21917. PMID 26912421 DOI: 10.1038/srep21917 |
0.418 |
|
| 2015 |
Varvel NH, Grathwohl SA, Degenhardt K, Resch C, Bosch A, Jucker M, Neher JJ. Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease. The Journal of Experimental Medicine. 212: 1803-9. PMID 26458770 DOI: 10.1084/Jem.20150478 |
0.637 |
|
| 2015 |
Jucker M, Walker LC. Neurodegeneration: Amyloid-β pathology induced in humans. Nature. 525: 193-4. PMID 26354478 DOI: 10.1038/525193A |
0.4 |
|
| 2015 |
Ye L, Fritschi SK, Schelle J, Obermüller U, Degenhardt K, Kaeser SA, Eisele YS, Walker LC, Baumann F, Staufenbiel M, Jucker M. Persistence of Aβ seeds in APP null mouse brain. Nature Neuroscience. 18: 1559-61. PMID 26352792 DOI: 10.1038/Nn.4117 |
0.528 |
|
| 2015 |
Maia LF, Kaeser SA, Reichwald J, Lambert M, Obermüller U, Schelle J, Odenthal J, Martus P, Staufenbiel M, Jucker M. Increased CSF Aβ during the very early phase of cerebral Aβ deposition in mouse models. Embo Molecular Medicine. 7: 895-903. PMID 25978969 DOI: 10.15252/emmm.201505026 |
0.394 |
|
| 2015 |
Mahler J, Morales-Corraliza J, Stolz J, Skodras A, Radde R, Duma CC, Eisele YS, Mazzella MJ, Wong H, Klunk WE, Nilsson KP, Staufenbiel M, Mathews PM, Jucker M, Wegenast-Braun BM. Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice. Neurobiology of Aging. 36: 2241-7. PMID 25911278 DOI: 10.1016/J.Neurobiolaging.2015.03.011 |
0.461 |
|
| 2015 |
Ye L, Hamaguchi T, Fritschi SK, Eisele YS, Obermüller U, Jucker M, Walker LC. Progression of Seed-Induced Aβ Deposition within the Limbic Connectome. Brain Pathology (Zurich, Switzerland). PMID 25677332 DOI: 10.1111/Bpa.12252 |
0.538 |
|
| 2014 |
Maier FC, Wehrl HF, Schmid AM, Mannheim JG, Wiehr S, Lerdkrai C, Calaminus C, Stahlschmidt A, Ye L, Burnet M, Stiller D, Sabri O, Reischl G, Staufenbiel M, Garaschuk O, ... Jucker M, et al. Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion. Nature Medicine. 20: 1485-92. PMID 25384087 DOI: 10.1038/nm.3734 |
0.414 |
|
| 2014 |
Schweighauser M, Bacioglu M, Fritschi SK, Shimshek DR, Kahle PJ, Eisele YS, Jucker M. Formaldehyde-fixed brain tissue from spontaneously ill α-synuclein transgenic mice induces fatal α-synucleinopathy in transgenic hosts. Acta Neuropathologica. 129: 157-9. PMID 25367384 DOI: 10.1007/s00401-014-1360-5 |
0.306 |
|
| 2014 |
Fritschi SK, Langer F, Kaeser SA, Maia LF, Portelius E, Pinotsi D, Kaminski CF, Winkler DT, Maetzler W, Keyvani K, Spitzer P, Wiltfang J, Kaminski Schierle GS, Zetterberg H, Staufenbiel M, ... Jucker M, et al. Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid. Brain : a Journal of Neurology. 137: 2909-2915. PMID 25212850 DOI: 10.1093/brain/awu255 |
0.511 |
|
| 2014 |
Fritschi SK, Cintron A, Ye L, Mahler J, Bühler A, Baumann F, Neumann M, Nilsson KP, Hammarström P, Walker LC, Jucker M. Aβ seeds resist inactivation by formaldehyde. Acta Neuropathologica. 128: 477-84. PMID 25193240 DOI: 10.1007/S00401-014-1339-2 |
0.512 |
|
| 2014 |
Gowert NS, Donner L, Chatterjee M, Eisele YS, Towhid ST, Münzer P, Walker B, Ogorek I, Borst O, Grandoch M, Schaller M, Fischer JW, Gawaz M, Weggen S, Lang F, ... Jucker M, et al. Blood platelets in the progression of Alzheimer's disease. Plos One. 9: e90523. PMID 24587388 DOI: 10.1371/Journal.Pone.0090523 |
0.325 |
|
| 2014 |
Hefendehl JK, Neher JJ, Sühs RB, Kohsaka S, Skodras A, Jucker M. Homeostatic and injury-induced microglia behavior in the aging brain Aging Cell. 13: 60-69. PMID 23953759 DOI: 10.1111/Acel.12149 |
0.394 |
|
| 2013 |
Nagarathinam A, Höflinger P, Bühler A, Schäfer C, McGovern G, Jeffrey M, Staufenbiel M, Jucker M, Baumann F. Membrane-anchored Aβ accelerates amyloid formation and exacerbates amyloid-associated toxicity in mice Journal of Neuroscience. 33: 19284-19294. PMID 24305824 DOI: 10.1523/JNEUROSCI.2542-13.2013 |
0.35 |
|
| 2013 |
Heilbronner G, Eisele YS, Langer F, Kaeser SA, Novotny R, Nagarathinam A, Aslund A, Hammarström P, Nilsson KP, Jucker M. Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice. Embo Reports. 14: 1017-22. PMID 23999102 DOI: 10.1038/Embor.2013.137 |
0.513 |
|
| 2013 |
Grathwohl SA, Jucker M. Replacement of osmotic minipumps to extend the intracerebral infusion time of compounds into the mouse brain. Biotechniques. 55: 75-8. PMID 23931595 DOI: 10.2144/000114064 |
0.34 |
|
| 2013 |
Maia LF, Kaeser SA, Reichwald J, Hruscha M, Martus P, Staufenbiel M, Jucker M. Changes in amyloid-β and tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein Science Translational Medicine. 5. PMID 23863834 DOI: 10.1126/scitranslmed.3006446 |
0.474 |
|
| 2013 |
Veeraraghavalu K, Zhang C, Miller S, Hefendehl JK, Rajapaksha TW, Ulrich J, Jucker M, Holtzman DM, Tanzi RE, Vassar R, Sisodia SS. Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (New York, N.Y.). 340: 924-f. PMID 23704555 DOI: 10.1126/Science.1235505 |
0.357 |
|
| 2013 |
Nyström S, Psonka-Antonczyk KM, Ellingsen PG, Johansson LB, Reitan N, Handrick S, Prokop S, Heppner FL, Wegenast-Braun BM, Jucker M, Lindgren M, Stokke BT, Hammarström P, Nilsson KP. Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits. Acs Chemical Biology. 8: 1128-33. PMID 23521783 DOI: 10.1021/Cb4000376 |
0.488 |
|
| 2013 |
Morales-Corraliza J, Schmidt SD, Mazzella MJ, Berger JD, Wilson DA, Wesson DW, Jucker M, Levy E, Nixon RA, Mathews PM. Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model. Neurobiology of Aging. 34: 137-45. PMID 22608241 DOI: 10.1016/J.Neurobiolaging.2012.04.007 |
0.492 |
|
| 2012 |
Varvel NH, Grathwohl SA, Baumann F, Liebig C, Bosch A, Brawek B, Thal DR, Charo IF, Heppner FL, Aguzzi A, Garaschuk O, Ransohoff RM, Jucker M. Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 18150-5. PMID 23071306 DOI: 10.1073/Pnas.1210150109 |
0.606 |
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| 2012 |
Wegenast-Braun BM, Skodras A, Bayraktar G, Mahler J, Fritschi SK, Klingstedt T, Mason JJ, Hammarström P, Nilsson KP, Liebig C, Jucker M. Spectral discrimination of cerebral amyloid lesions after peripheral application of luminescent conjugated oligothiophenes. The American Journal of Pathology. 181: 1953-60. PMID 23041059 DOI: 10.1016/J.Ajpath.2012.08.031 |
0.472 |
|
| 2012 |
Eisenberg D, Jucker M. The amyloid state of proteins in human diseases. Cell. 148: 1188-203. PMID 22424229 DOI: 10.1016/J.Cell.2012.02.022 |
0.309 |
|
| 2012 |
Hamaguchi T, Eisele YS, Varvel NH, Lamb BT, Walker LC, Jucker M. The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain. Acta Neuropathologica. 123: 31-7. PMID 22101366 DOI: 10.1007/S00401-011-0912-1 |
0.564 |
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| 2012 |
Rosen RF, Fritz JJ, Dooyema J, Cintron AF, Hamaguchi T, Lah JJ, LeVine H, Jucker M, Walker LC. Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats. Journal of Neurochemistry. 120: 660-6. PMID 22017494 DOI: 10.1111/J.1471-4159.2011.07551.X |
0.466 |
|
| 2011 |
Jucker M, Walker LC. Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders. Annals of Neurology. 70: 532-40. PMID 22028219 DOI: 10.1002/Ana.22615 |
0.375 |
|
| 2011 |
Langer F, Eisele YS, Fritschi SK, Staufenbiel M, Walker LC, Jucker M. Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14488-95. PMID 21994365 DOI: 10.1523/Jneurosci.3088-11.2011 |
0.523 |
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| 2011 |
Kilger E, Buehler A, Woelfing H, Kumar S, Kaeser SA, Nagarathinam A, Walter J, Jucker M, Coomaraswamy J. BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE). The Journal of Biological Chemistry. 286: 37446-57. PMID 21873424 DOI: 10.1074/jbc.M111.288373 |
0.408 |
|
| 2011 |
Walker LC, Jucker M. Amyloid by default. Nature Neuroscience. 14: 669-70. PMID 21613991 DOI: 10.1038/Nn.2853 |
0.426 |
|
| 2011 |
Roesli C, Fugmann T, Borgia B, Schliemann C, Neri D, Jucker M. The accessible cerebral vascular proteome in a mouse model of cerebral β-amyloidosis. Journal of Proteomics. 74: 539-46. PMID 21262399 DOI: 10.1016/j.jprot.2011.01.010 |
0.337 |
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| 2011 |
Hefendehl JK, Wegenast-Braun BM, Liebig C, Eicke D, Milford D, Calhoun ME, Kohsaka S, Eichner M, Jucker M. Long-term in vivo imaging of β-amyloid plaque appearance and growth in a mouse model of cerebral β-amyloidosis Journal of Neuroscience. 31: 624-629. PMID 21228171 DOI: 10.1523/Jneurosci.5147-10.2011 |
0.5 |
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| 2010 |
Rupp NJ, Wegenast-Braun BM, Radde R, Calhoun ME, Jucker M. Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice. Neurobiology of Aging. 32: 2324.e1-6. PMID 20970889 DOI: 10.1016/j.neurobiolaging.2010.08.014 |
0.369 |
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| 2010 |
Eisele YS, Obermüller U, Heilbronner G, Baumann F, Kaeser SA, Wolburg H, Walker LC, Staufenbiel M, Heikenwalder M, Jucker M. Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science (New York, N.Y.). 330: 980-2. PMID 20966215 DOI: 10.1126/Science.1194516 |
0.491 |
|
| 2010 |
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, ... Jucker M, et al. Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 7969-74. PMID 20385796 DOI: 10.1073/Pnas.1001056107 |
0.484 |
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| 2009 |
Grathwohl SA, Kälin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, ... Jucker M, et al. Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nature Neuroscience. 12: 1361-3. PMID 19838177 DOI: 10.1515/Nf-2010-0107 |
0.443 |
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| 2009 |
Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, et al. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. Acs Chemical Biology. 4: 673-84. PMID 19624097 DOI: 10.1021/Cb900112V |
0.399 |
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| 2009 |
Eisele YS, Bolmont T, Heikenwalder M, Langer F, Jacobson LH, Yan ZX, Roth K, Aguzzi A, Staufenbiel M, Walker LC, Jucker M. Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation. Proceedings of the National Academy of Sciences of the United States of America. 106: 12926-31. PMID 19622727 DOI: 10.1073/Pnas.0903200106 |
0.424 |
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| 2009 |
Wegenast-Braun BM, Fulgencio Maisch A, Eicke D, Radde R, Herzig MC, Staufenbiel M, Jucker M, Calhoun ME. Independent effects of intra- and extracellular Abeta on learning-related gene expression. The American Journal of Pathology. 175: 271-82. PMID 19556514 DOI: 10.2353/ajpath.2009.090044 |
0.461 |
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| 2009 |
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nature Cell Biology. 11: 909-13. PMID 19503072 DOI: 10.1038/Ncb1901 |
0.44 |
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| 2009 |
Herzig MC, Eisele YS, Staufenbiel M, Jucker M. E22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition. The American Journal of Pathology. 174: 722-6. PMID 19218342 DOI: 10.2353/ajpath.2009.080790 |
0.425 |
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| 2008 |
Jucker M, Heppner FL. Cerebral and peripheral amyloid phagocytes--an old liaison with a new twist. Neuron. 59: 8-10. PMID 18614025 DOI: 10.1016/j.neuron.2008.06.014 |
0.451 |
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| 2008 |
Ermini FV, Grathwohl S, Radde R, Yamaguchi M, Staufenbiel M, Palmer TD, Jucker M. Neurogenesis and alterations of neural stem cells in mouse models of cerebral amyloidosis. The American Journal of Pathology. 172: 1520-8. PMID 18467698 DOI: 10.2353/ajpath.2008.060520 |
0.464 |
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| 2008 |
Bolmont T, Haiss F, Eicke D, Radde R, Mathis CA, Klunk WE, Kohsaka S, Jucker M, Calhoun ME. Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4283-92. PMID 18417708 DOI: 10.1523/Jneurosci.4814-07.2008 |
0.435 |
|
| 2008 |
Radde R, Duma C, Goedert M, Jucker M. The value of incomplete mouse models of Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 35: S70-4. PMID 18270700 DOI: 10.1007/S00259-007-0704-Y |
0.437 |
|
| 2007 |
Bolmont T, Clavaguera F, Meyer-Luehmann M, Herzig MC, Radde R, Staufenbiel M, Lewis J, Hutton M, Tolnay M, Jucker M. Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice. The American Journal of Pathology. 171: 2012-20. PMID 18055549 DOI: 10.2353/Ajpath.2007.070403 |
0.412 |
|
| 2007 |
Eisele YS, Baumann M, Klebl B, Nordhammer C, Jucker M, Kilger E. Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-beta degrading enzyme neprilysin. Molecular Biology of the Cell. 18: 3591-600. PMID 17626163 DOI: 10.1091/mbc.e07-01-0035 |
0.349 |
|
| 2007 |
Kuhnke D, Jedlitschky G, Grube M, Krohn M, Jucker M, Mosyagin I, Cascorbi I, Walker LC, Kroemer HK, Warzok RW, Vogelgesang S. MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier. Brain Pathology (Zurich, Switzerland). 17: 347-53. PMID 17610523 DOI: 10.1111/J.1750-3639.2007.00075.X |
0.375 |
|
| 2007 |
Herzig MC, Paganetti P, Staufenbiel M, Jucker M. BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice. Neuro-Degenerative Diseases. 4: 127-35. PMID 17596707 DOI: 10.1159/000101837 |
0.434 |
|
| 2007 |
Burbach GJ, Vlachos A, Ghebremedhin E, Del Turco D, Coomaraswamy J, Staufenbiel M, Jucker M, Deller T. Vessel ultrastructure in APP23 transgenic mice after passive anti-Abeta immunotherapy and subsequent intracerebral hemorrhage. Neurobiology of Aging. 28: 202-12. PMID 16427722 DOI: 10.1016/j.neurobiolaging.2005.12.003 |
0.365 |
|
| 2006 |
Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, ... ... Jucker M, et al. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science (New York, N.Y.). 313: 1781-4. PMID 16990547 DOI: 10.1126/Science.1131864 |
0.419 |
|
| 2006 |
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jäggi F, Wolburg H, Gengler S, Haass C, Ghetti B, Czech C, Hölscher C, Mathews PM, ... Jucker M, et al. Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. Embo Reports. 7: 940-6. PMID 16906128 DOI: 10.1038/Sj.Embor.7400784 |
0.433 |
|
| 2006 |
Pickford F, Coomaraswamy J, Jucker M, McGowan E. Modeling familial British dementia in transgenic mice. Brain Pathology (Zurich, Switzerland). 16: 80-5. PMID 16612985 DOI: 10.1111/J.1750-3639.2006.Tb00564.X |
0.345 |
|
| 2006 |
Herzig MC, Van Nostrand WE, Jucker M. Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models. Brain Pathology (Zurich, Switzerland). 16: 40-54. PMID 16612981 DOI: 10.1111/j.1750-3639.2006.tb00560.x |
0.383 |
|
| 2005 |
Buffo A, Vosko MR, Ertürk D, Hamann GF, Jucker M, Rowitch D, Götz M. Expression pattern of the transcription factor Olig2 in response to brain injuries: Implications for neuronal repair Proceedings of the National Academy of Sciences of the United States of America. 102: 18183-18188. PMID 16330768 DOI: 10.1073/Pnas.0506535102 |
0.331 |
|
| 2005 |
Stalder AK, Ermini F, Bondolfi L, Krenger W, Burbach GJ, Deller T, Coomaraswamy J, Staufenbiel M, Landmann R, Jucker M. Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11125-32. PMID 16319312 DOI: 10.1523/JNEUROSCI.2545-05.2005 |
0.534 |
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| 2005 |
Walker LC, Ibegbu CC, Todd CW, Robinson HL, Jucker M, LeVine H, Gandy S. Emerging prospects for the disease-modifying treatment of Alzheimer's disease. Biochemical Pharmacology. 69: 1001-8. PMID 15763538 DOI: 10.1016/J.Bcp.2004.12.015 |
0.458 |
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| 2005 |
Boncristiano S, Calhoun ME, Howard V, Bondolfi L, Kaeser SA, Wiederhold KH, Staufenbiel M, Jucker M. Neocortical synaptic bouton number is maintained despite robust amyloid deposition in APP23 transgenic mice. Neurobiology of Aging. 26: 607-13. PMID 15708435 DOI: 10.1016/j.neurobiolaging.2004.06.010 |
0.444 |
|
| 2005 |
Syková E, Vorísek I, Antonova T, Mazel T, Meyer-Luehmann M, Jucker M, Hájek M, Ort M, Or M, Bures J. Changes in extracellular space size and geometry in APP23 transgenic mice: a model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 479-84. PMID 15630088 DOI: 10.1073/Pnas.0408235102 |
0.303 |
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| 2004 |
Herzig MC, Winkler DT, Burgermeister P, Pfeifer M, Kohler E, Schmidt SD, Danner S, Abramowski D, Stürchler-Pierrat C, Bürki K, van Duinen SG, Maat-Schieman ML, Staufenbiel M, Mathews PM, Jucker M. Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis. Nature Neuroscience. 7: 954-60. PMID 15311281 DOI: 10.1038/Nn1302 |
0.488 |
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| 2004 |
Mueggler T, Meyer-Luehmann M, Rausch M, Staufenbiel M, Jucker M, Rudin M. Restricted diffusion in the brain of transgenic mice with cerebral amyloidosis. The European Journal of Neuroscience. 20: 811-7. PMID 15255991 DOI: 10.1111/J.1460-9568.2004.03534.X |
0.501 |
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| 2004 |
Bondolfi L, Ermini F, Long JM, Ingram DK, Jucker M. Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice. Neurobiology of Aging. 25: 333-40. PMID 15123339 DOI: 10.1016/S0197-4580(03)00083-6 |
0.3 |
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| 2004 |
Burbach GJ, Hellweg R, Haas CA, Del Turco D, Deicke U, Abramowski D, Jucker M, Staufenbiel M, Deller T. Induction of brain-derived neurotrophic factor in plaque-associated glial cells of aged APP23 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2421-30. PMID 15014117 DOI: 10.1523/JNEUROSCI.5599-03.2004 |
0.428 |
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| 2003 |
Meyer-Luehmann M, Stalder M, Herzig MC, Kaeser SA, Kohler E, Pfeifer M, Boncristiano S, Mathews PM, Mercken M, Abramowski D, Staufenbiel M, Jucker M. Extracellular amyloid formation and associated pathology in neural grafts. Nature Neuroscience. 6: 370-7. PMID 12598899 DOI: 10.1038/Nn1022 |
0.413 |
|
| 2002 |
Mouton PR, Long JM, Lei DL, Howard V, Jucker M, Calhoun ME, Ingram DK. Age and gender effects on microglia and astrocyte numbers in brains of mice. Brain Research. 956: 30-5. PMID 12426043 DOI: 10.1016/S0006-8993(02)03475-3 |
0.333 |
|
| 2002 |
Winkler DT, Biedermann L, Tolnay M, Allegrini PR, Staufenbiel M, Wiessner C, Jucker M. Thrombolysis induces cerebral hemorrhage in a mouse model of cerebral amyloid angiopathy. Annals of Neurology. 51: 790-3. PMID 12112090 DOI: 10.1002/ana.10210 |
0.34 |
|
| 2002 |
Boncristiano S, Calhoun ME, Kelly PH, Pfeifer M, Bondolfi L, Stalder M, Phinney AL, Abramowski D, Sturchler-Pierrat C, Enz A, Sommer B, Staufenbiel M, Jucker M. Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3234-43. PMID 11943824 DOI: 20026314 |
0.372 |
|
| 2002 |
Bondolfi L, Calhoun M, Ermini F, Georg Kuhn H, Wiederhold KH, Walker L, Staufenbiel M, Jucker M. Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice Journal of Neuroscience. 22: 515-522. PMID 11784797 DOI: 10.1523/Jneurosci.22-02-00515.2002 |
0.337 |
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