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Viviana Gradinaru - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
 Neuroscience California Institute of Technology, Pasadena, CA 
Area:
Control of Brain Function and Behavior
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Oikonomou G, Altermatt M, Zhang RW, Coughlin GM, Montz C, Gradinaru V, Prober DA. The Serotonergic Raphe Promote Sleep in Zebrafish and Mice. Neuron. PMID 31248729 DOI: 10.1016/j.neuron.2019.05.038  0.48
2019 Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, et al. Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. Nature Communications. 10: 1944. PMID 31028266 DOI: 10.1038/s41467-019-09770-1  0.52
2019 Zeng J, Wang Y, Luo Z, Chang LC, Yoo JS, Yan H, Choi Y, Xie X, Deverman BE, Gradinaru V, Gupton SL, Zlokovic BV, Zhao Z, Jung JU. TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice. Cell Reports. 27: 549-560.e6. PMID 30970257 DOI: 10.1016/j.celrep.2018.12.055  0.48
2019 Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nature Protocols. PMID 30626963 DOI: 10.1038/s41596-018-0097-3  0.48
2018 Mano T, Albanese A, Dodt HU, Erturk A, Gradinaru V, Treweek JB, Miyawaki A, Chung K, Ueda HR. Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 9330-9337. PMID 30381424 DOI: 10.1523/JNEUROSCI.1677-18.2018  0.52
2018 Gradinaru V, Treweek J, Overton K, Deisseroth K. Hydrogel-Tissue Chemistry: Principles and Applications. Annual Review of Biophysics. 47: 355-376. PMID 29792820 DOI: 10.1146/annurev-biophys-070317-032905  0.72
2018 Zelikowsky M, Hui M, Karigo T, Choe A, Yang B, Blanco MR, Beadle K, Gradinaru V, Deverman BE, Anderson DJ. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 173: 1265-1279.e19. PMID 29775595 DOI: 10.1016/j.cell.2018.03.037  0.48
2018 Bedbrook CN, Deverman BE, Gradinaru V. Viral Strategies for Targeting the Central and Peripheral Nervous Systems. Annual Review of Neuroscience. PMID 29709207 DOI: 10.1146/annurev-neuro-080317-062048  0.48
2017 Ruan H, Brake J, Robinson JE, Liu Y, Jang M, Xiao C, Zhou C, Gradinaru V, Yang C. Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light. Science Advances. 3: eaao5520. PMID 29226248 DOI: 10.1126/sciadv.aao5520  0.76
2017 Bedbrook CN, Yang KK, Rice AJ, Gradinaru V, Arnold FH. Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization. Plos Computational Biology. 13: e1005786. PMID 29059183 DOI: 10.1371/journal.pcbi.1005786  0.44
2017 Greenbaum A, Jang MJ, Challis C, Gradinaru V. Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology? Bmc Biology. 15: 87. PMID 28946882 DOI: 10.1186/s12915-017-0421-3  0.52
2017 Nath RD, Bedbrook CN, Abrams MJ, Basinger T, Bois JS, Prober DA, Sternberg PW, Gradinaru V, Goentoro L. The Jellyfish Cassiopea Exhibits a Sleep-like State. Current Biology : Cb. PMID 28943083 DOI: 10.1016/j.cub.2017.08.014  0.48
2017 Robinson JE, Gradinaru V. Dopaminergic dysfunction in neurodevelopmental disorders: recent advances and synergistic technologies to aid basic research. Current Opinion in Neurobiology. 48: 17-29. PMID 28850815 DOI: 10.1016/j.conb.2017.08.003  0.76
2017 Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sánchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V. Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems. Nature Neuroscience. PMID 28671695 DOI: 10.1038/nn.4593  0.52
2017 Cho JR, Treweek JB, Robinson JE, Xiao C, Bremner LR, Greenbaum A, Gradinaru V. Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness by Salient Stimuli. Neuron. PMID 28602690 DOI: 10.1016/j.neuron.2017.05.020  0.76
2017 Allen WE, Kauvar IV, Chen MZ, Richman EB, Yang SJ, Chan K, Gradinaru V, Deverman BE, Luo L, Deisseroth K. Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex. Neuron. 94: 891-907.e6. PMID 28521139 DOI: 10.1016/j.neuron.2017.04.017  0.72
2017 Greenbaum A, Chan KY, Dobreva T, Brown D, Balani DH, Boyce R, Kronenberg HM, McBride HJ, Gradinaru V. Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow. Science Translational Medicine. 9. PMID 28446689 DOI: 10.1126/scitranslmed.aah6518  0.52
2017 Bedbrook CN, Rice AJ, Yang KK, Ding X, Chen S, LeProust EM, Gradinaru V, Arnold FH. Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins. Proceedings of the National Academy of Sciences of the United States of America. PMID 28283661 DOI: 10.1073/pnas.1700269114  0.44
2017 Herwig L, Rice AJ, Bedbrook CN, Zhang RK, Lignell A, Cahn JK, Renata H, Dodani SC, Cho I, Cai L, Gradinaru V, Arnold FH. Directed Evolution of a Bright Near-Infrared Fluorescent Rhodopsin Using a Synthetic Chromophore. Cell Chemical Biology. PMID 28262559 DOI: 10.1016/j.chembiol.2017.02.008  0.44
2016 Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet MF, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, et al. Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease. Cell. 167: 1469-1480.e12. PMID 27912057 DOI: 10.1016/j.cell.2016.11.018  0.48
2016 Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W, Song C, Xu X, Schones DE, Ann DK, ... Gradinaru V, et al. Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation. Nature Cell Biology. PMID 27617932 DOI: 10.1038/ncb3410  0.72
2016 Treweek JB, Gradinaru V. Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors. Current Opinion in Biotechnology. 40: 193-207. PMID 27393829 DOI: 10.1016/j.copbio.2016.03.012  0.52
2016 Shah S, Lubeck E, Schwarzkopf M, He TF, Greenbaum A, Sohn CH, Lignell A, Choi HM, Gradinaru V, Pierce NA, Cai L. Single-molecule RNA detection at depth via hybridization chain reaction and tissue hydrogel embedding and clearing. Development (Cambridge, England). PMID 27342713 DOI: 10.1242/dev.138560  0.72
2016 Xiao C, Cho JR, Zhou C, Treweek JB, Chan K, McKinney SL, Yang B, Gradinaru V. Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. Neuron. 90: 333-347. PMID 27100197 DOI: 10.1016/j.neuron.2016.03.028  0.72
2016 Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature Biotechnology. PMID 26829320 DOI: 10.1038/nbt.3440  0.72
2016 Gradinaru V, Flytzanis NC. Neuroscience: Fluorescent boost for voltage sensors. Nature. 529: 469-70. PMID 26819038 DOI: 10.1038/529469a  0.72
2015 Skennerton CT, Ward LM, Michel A, Metcalfe K, Valiente C, Mullin S, Chan KY, Gradinaru V, Orphan VJ. Genomic Reconstruction of an Uncultured Hydrothermal Vent Gammaproteobacterial Methanotroph (Family Methylothermaceae) Indicates Multiple Adaptations to Oxygen Limitation. Frontiers in Microbiology. 6: 1425. PMID 26779119 DOI: 10.3389/fmicb.2015.01425  0.72
2015 Treweek JB, Chan KY, Flytzanis NC, Yang B, Deverman BE, Greenbaum A, Lignell A, Xiao C, Cai L, Ladinsky MS, Bjorkman PJ, Fowlkes CC, Gradinaru V. Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping. Nature Protocols. 10: 1860-96. PMID 26492141 DOI: 10.1038/nprot.2015.122  0.72
2015 Bedbrook CN, Kato M, Ravindra Kumar S, Lakshmanan A, Nath RD, Sun F, Sternberg PW, Arnold FH, Gradinaru V. Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo. Chemistry & Biology. 22: 1108-21. PMID 26211362 DOI: 10.1016/j.chembiol.2015.06.020  0.44
2015 Bedbrook CN, Kato M, Ravindra kumar S, Lakshmanan A, Nath RD, Sun F, Sternberg PW, Arnold FH, Gradinaru V. Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo Chemistry and Biology. 22: 1108-1121. DOI: 10.1016/j.chembiol.2015.06.020  0.72
2014 Flytzanis NC, Bedbrook CN, Chiu H, Engqvist MK, Xiao C, Chan KY, Sternberg PW, Arnold FH, Gradinaru V. Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons. Nature Communications. 5: 4894. PMID 25222271 DOI: 10.1038/ncomms5894  0.52
2014 McIsaac RS, Engqvist MK, Wannier T, Rosenthal AZ, Herwig L, Flytzanis NC, Imasheva ES, Lanyi JK, Balashov SP, Gradinaru V, Arnold FH. Directed evolution of a far-red fluorescent rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 111: 13034-9. PMID 25157169 DOI: 10.1073/pnas.1413987111  0.72
2014 Yang B, Treweek JB, Kulkarni RP, Deverman BE, Chen CK, Lubeck E, Shah S, Cai L, Gradinaru V. Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell. 158: 945-58. PMID 25088144 DOI: 10.1016/j.cell.2014.07.017  0.72
2014 Birmingham K, Gradinaru V, Anikeeva P, Grill WM, Pikov V, McLaughlin B, Pasricha P, Weber D, Ludwig K, Famm K. Bioelectronic medicines: a research roadmap. Nature Reviews. Drug Discovery. 13: 399-400. PMID 24875080 DOI: 10.1038/nrd4351  0.72
2014 Pienaar IS, Dexter DT, Gradinaru V. Neurophysiological and Optogenetic Assessment of Brain Networks Involved in Motor Control Movement Disorders: Genetics and Models: Second Edition. 187-199. DOI: 10.1016/B978-0-12-405195-9.00011-1  0.72
2013 Sukhotinsky I, Chan AM, Ahmed OJ, Rao VR, Gradinaru V, Ramakrishnan C, Deisseroth K, Majewska AK, Cash SS. Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy model. Plos One. 8: e62013. PMID 23637949 DOI: 10.1371/journal.pone.0062013  0.72
2013 Chung K, Wallace J, Kim SY, Kalyanasundaram S, Andalman AS, Davidson TJ, Mirzabekov JJ, Zalocusky KA, Mattis J, Denisin AK, Pak S, Bernstein H, Ramakrishnan C, Grosenick L, Gradinaru V, et al. Structural and molecular interrogation of intact biological systems. Nature. 497: 332-7. PMID 23575631 DOI: 10.1038/nature12107  0.72
2012 Mattis J, Tye KM, Ferenczi EA, Ramakrishnan C, O'Shea DJ, Prakash R, Gunaydin LA, Hyun M, Fenno LE, Gradinaru V, Yizhar O, Deisseroth K. Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins. Nature Methods. 9: 159-72. PMID 22179551 DOI: 10.1038/nmeth.1808  0.72
2011 Domingos AI, Vaynshteyn J, Voss HU, Ren X, Gradinaru V, Zang F, Deisseroth K, de Araujo IE, Friedman J. Leptin regulates the reward value of nutrient. Nature Neuroscience. 14: 1562-8. PMID 22081158 DOI: 10.1038/nn.2977  0.72
2011 Goshen I, Brodsky M, Prakash R, Wallace J, Gradinaru V, Ramakrishnan C, Deisseroth K. Dynamics of retrieval strategies for remote memories. Cell. 147: 678-89. PMID 22019004 DOI: 10.1016/j.cell.2011.09.033  0.72
2011 Tye KM, Prakash R, Kim SY, Fenno LE, Grosenick L, Zarabi H, Thompson KR, Gradinaru V, Ramakrishnan C, Deisseroth K. Amygdala circuitry mediating reversible and bidirectional control of anxiety. Nature. 471: 358-62. PMID 21389985 DOI: 10.1038/nature09820  0.72
2010 Witten IB, Lin SC, Brodsky M, Prakash R, Diester I, Anikeeva P, Gradinaru V, Ramakrishnan C, Deisseroth K. Cholinergic interneurons control local circuit activity and cocaine conditioning. Science (New York, N.Y.). 330: 1677-81. PMID 21164015 DOI: 10.1126/science.1193771  0.72
2010 Lee JH, Durand R, Gradinaru V, Zhang F, Goshen I, Kim DS, Fenno LE, Ramakrishnan C, Deisseroth K. Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature. 465: 788-92. PMID 20473285 DOI: 10.1038/nature09108  0.72
2010 Gradinaru V, Zhang F, Ramakrishnan C, Mattis J, Prakash R, Diester I, Goshen I, Thompson KR, Deisseroth K. Molecular and cellular approaches for diversifying and extending optogenetics. Cell. 141: 154-65. PMID 20303157 DOI: 10.1016/j.cell.2010.02.037  0.72
2010 Zhang F, Gradinaru V, Adamantidis AR, Durand R, Airan RD, de Lecea L, Deisseroth K. Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. Nature Protocols. 5: 439-56. PMID 20203662 DOI: 10.1038/nprot.2009.226  0.72
2010 Lee JH, Durand R, Gradinaru V, Zhang F, Goshen I, Kim DS, Fenno LE, Ramakrishnan C, Deisseroth K. Lee et al. reply Nature. 468: E4-E5. DOI: 10.1038/nature09533  0.72
2009 Gradinaru V, Mogri M, Thompson KR, Henderson JM, Deisseroth K. Optical deconstruction of parkinsonian neural circuitry. Science (New York, N.Y.). 324: 354-9. PMID 19299587 DOI: 10.1126/science.1167093  0.72
2008 Gradinaru V, Thompson KR, Deisseroth K. eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications. Brain Cell Biology. 36: 129-39. PMID 18677566 DOI: 10.1007/s11068-008-9027-6  0.72
2008 Schneider MB, Gradinaru V, Zhang F, Deisseroth K. Controlling neuronal activity. The American Journal of Psychiatry. 165: 562. PMID 18450936 DOI: 10.1176/appi.ajp.2008.08030444  0.72
2007 Gradinaru V, Thompson KR, Zhang F, Mogri M, Kay K, Schneider MB, Deisseroth K. Targeting and readout strategies for fast optical neural control in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14231-8. PMID 18160630 DOI: 10.1523/JNEUROSCI.3578-07.2007  0.72
1985 Seicaru T, Grădinaru V, Andronescu P. [Postoperative peptic ulcers. Prognostic and surgical management characteristics]. Revista De Chirurgie, Oncologie, Radiologie, O.R.L., Oftalmologie, Stomatologie. Chirurgie. 34: 99-112. PMID 3160078  0.32
1978 Seicaru T, Grădinaru V, Marin MA, Andronescu P, Lotreanu S. [Phlegmonous gastritis]. Revista De Chirurgie, Oncologie, Radiologie, O.R.L., Oftalmologie, Stomatologie. Chirurgie. 27: 177-9. PMID 694068  0.32
1975 Seicaru T, Grădinaru V, Andronescu P, Rădulescu M, Zugravu B, Marin MA, Toma G, Marcov A. [Spontaneous perforations of the pathological colon]. Revista De Chirurgie, Oncologie, Radiologie, O.R.L., Oftalmologie, Stomatologie. Chirurgie. 24: 273-6. PMID 127235  0.32
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