Jerold Chun - Publications

1991-2001 Pharmacology & Neuroscience University of California, San Diego, La Jolla, CA 
 2003-2016 Molecular Biology, Molecular and Cellular Neuroscience Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2016- Sanford Burnham Prebys Medical Discovery Institute 
Brain Genomic Mosaicism and Gene Recombination; LPA, S1P, Lysophospholipid Signaling

266 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kihara Y, Zhu Y, Jonnalagadda D, Romanow W, Palmer C, Siddoway B, Rivera R, Dutta R, Trapp BD, Chun J. Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod. Frontiers in Cellular Neuroscience. 16: 918041. PMID 35783097 DOI: 10.3389/fncel.2022.918041  0.79
2022 Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, ... ... Chun J, et al. Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. PMID 35319013 DOI: 10.1038/s41586-022-04562-y  0.7
2022 Kihara Y, Jonnalagadda D, Zhu Y, Ray M, Ngo T, Palmer C, Rivera R, Chun J. Ponesimod inhibits astrocyte-mediated neuroinflammation and protects against cingulum demyelination via S1P -selective modulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22132. PMID 34986275 DOI: 10.1096/fj.202101531R  0.613
2021 Palmer CR, Liu CS, Romanow WJ, Lee MH, Chun J. Altered cell and RNA isoform diversity in aging Down syndrome brains. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34795060 DOI: 10.1073/pnas.2114326118  0.739
2021 Rivera R, Williams NA, Kennedy GG, Sánchez-Pavón P, Chun J. Generation of an Lpar1-EGFP Fusion Knock-in Transgenic Mouse Line. Cell Biochemistry and Biophysics. 79: 619-627. PMID 34652685 DOI: 10.1007/s12013-021-01033-5  0.312
2021 Bakken TE, Jorstad NL, Hu Q, Lake BB, Tian W, Kalmbach BE, Crow M, Hodge RD, Krienen FM, Sorensen SA, Eggermont J, Yao Z, Aevermann BD, Aldridge AI, Bartlett A, ... ... Chun J, et al. Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature. 598: 111-119. PMID 34616062 DOI: 10.1038/s41586-021-03465-8  0.745
2021 Costantino I, Nicodemus J, Chun J. Genomic Mosaicism Formed by Somatic Variation in the Aging and Diseased Brain. Genes. 12. PMID 34356087 DOI: 10.3390/genes12071071  0.792
2020 McDonald WS, Miyamoto K, Rivera R, Kennedy G, Almeida BSV, Kingsbury MA, Chun J. Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells. Molecular Brain. 13: 169. PMID 33317583 DOI: 10.1186/s13041-020-00709-y  0.681
2020 Wang F, Liu S, Pei J, Cai L, Liu N, Liang T, Dong X, Cong X, Chun J, Chen J, Hu S, Chen X. LPA-mediated lysophosphatidic acid signaling promotes postnatal heart regeneration in mice. Theranostics. 10: 10892-10907. PMID 33042260 DOI: 10.7150/thno.47913  0.313
2020 Rivera RR, Lin ME, Bornhop EC, Chun J. Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 8833-8842. PMID 32929779 DOI: 10.1096/fj.202000317R  0.608
2020 Lee MH, Liu CS, Zhu Y, Kaeser GE, Rivera R, Romanow WJ, Kihara Y, Chun J. Reply to: APP gene copy number changes reflect exogenous contamination. Nature. 584: E29-E33. PMID 32814882 DOI: 10.1038/s41586-020-2523-2  0.769
2020 Kaeser G, Chun J. Brain cell somatic gene recombination and its phylogenetic foundations. The Journal of Biological Chemistry. PMID 32699111 DOI: 10.1074/Jbc.Rev120.009192  0.811
2020 Ray M, Nagai K, Kihara Y, Kussrow A, Kammer MN, Frantz A, Bornhop DJ, Chun J. Unlabeled lysophosphatidic acid receptor binding in free solution as determined by a compensated interferometric reader. Journal of Lipid Research. PMID 32513900 DOI: 10.1194/Jlr.D120000880  0.786
2020 Kaeser GE, Chun J. Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer's Disease. Frontiers in Genetics. 11: 390. PMID 32457796 DOI: 10.3389/fgene.2020.00390  0.782
2019 Gonzalez Gil I, Zian D, Vázquez-Villa H, Hernandez-Torres G, Martinez RF, Khiar-Fernandez N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Rosell Del Valle C, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, ... ... Chun J, et al. A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration. Journal of Medicinal Chemistry. PMID 31790581 DOI: 10.1021/Acs.Jmedchem.9B01287  0.307
2019 Lummis NC, Sánchez-Pavón P, Kennedy G, Frantz AJ, Kihara Y, Blaho VA, Chun J. LPA overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction. Science Advances. 5: eaax2011. PMID 31633020 DOI: 10.1126/sciadv.aax2011  0.794
2019 González de San Román E, Manuel I, Ledent C, Chun J, Rodríguez de Fonseca F, Estivill-Torrús G, Santín LJ, Rodríguez Puertas R. CB and LPA Receptors Relationship in the Mouse Central Nervous System. Frontiers in Molecular Neuroscience. 12: 223. PMID 31607860 DOI: 10.3389/fnmol.2019.00223  0.429
2019 Miyabe C, Miyabe Y, Nagai J, Miura NN, Ohno N, Chun J, Tsuboi R, Ueda H, Miyasaka M, Miyasaka N, Nanki T. Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis. Arthritis Research & Therapy. 21: 191. PMID 31429784 DOI: 10.1186/s13075-019-1973-0  0.361
2019 Tabbai S, Moreno-Fernández RD, Zambrana-Infantes E, Nieto-Quero A, Chun J, García-Fernández M, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Oliveira TG, Pérez-Martín M, Pedraza C. Effects of the LPA Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice. Frontiers in Molecular Neuroscience. 12: 146. PMID 31244601 DOI: 10.3389/fnmol.2019.00146  0.322
2019 Lee MH, Chun J. Mosaic Gene Recombination in Alzheimer's Disease-What's Next? Journal of Experimental Neuroscience. 13: 1179069519849669. PMID 31205422 DOI: 10.1177/1179069519849669  0.335
2019 Suckau O, Gross I, Schrötter S, Yang F, Luo J, Wree A, Chun J, Baska D, Baumgart J, Kano K, Aoki J, Bräuer AU. LPA , LPA , LPA , and LPA receptor expression during mouse brain development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 30847983 DOI: 10.1002/Dvdy.23  0.458
2019 Kano K, Matsumoto H, Inoue A, Yukiura H, Kanai M, Chun J, Ishii S, Shimizu T, Aoki J. Molecular mechanism of lysophosphatidic acid-induced hypertensive response. Scientific Reports. 9: 2662. PMID 30804442 DOI: 10.1038/s41598-019-39041-4  0.343
2019 Lee MH, Siddoway B, Kaeser GE, Segota I, Rivera R, Romanow WJ, Liu CS, Park C, Kennedy G, Long T, Chun J. Publisher Correction: Somatic APP gene recombination in Alzheimer's disease and normal neurons. Nature. PMID 30670873 DOI: 10.1038/S41586-019-0905-0  0.771
2019 Chun J, Kihara Y, Jonnalagadda D, Blaho VA. Fingolimod: Lessons Learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders. Annual Review of Pharmacology and Toxicology. 59: 149-170. PMID 30625282 DOI: 10.1146/annurev-pharmtox-010818-021358  0.359
2019 Kim NH, Sadra A, Park HY, Oh SM, Chun J, Yoon JK, Huh SO. HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells. Molecules and Cells. PMID 30622227 DOI: 10.14348/molcells.2018.0399  0.387
2018 López-Serrano C, Santos-Nogueira E, Francos-Quijorna I, Coll-Miró M, Chun J, López-Vales R. Lysophosphatidic acid receptor type 2 activation contributes to secondary damage after spinal cord injury in mice. Brain, Behavior, and Immunity. PMID 30550929 DOI: 10.1016/j.bbi.2018.12.007  0.35
2018 Lee MH, Siddoway B, Kaeser GE, Segota I, Rivera R, Romanow WJ, Liu CS, Park C, Kennedy G, Long T, Chun J. Somatic APP gene recombination in Alzheimer's disease and normal neurons. Nature. PMID 30464338 DOI: 10.1038/S41586-018-0718-6  0.802
2018 Mizuno H, Kihara Y, Kussrow A, Chen A, Ray M, Rivera R, Bornhop D, Chun J. Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry (BSI). Journal of Lipid Research. PMID 30463988 DOI: 10.1194/Jlr.D089938  0.314
2018 Blaho VA, Chun J. 'Crystal' Clear? Lysophospholipid Receptor Structure Insights and Controversies. Trends in Pharmacological Sciences. 39: 953-966. PMID 30343728 DOI: 10.1016/  0.349
2018 Srikanth M, Chew WS, Hind T, Lim SM, Hay NWJ, Lee JHM, Rivera R, Chun J, Ong WY, Herr DR. Lysophosphatidic acid and its receptor LPA mediate carrageenan induced inflammatory pain in mice. European Journal of Pharmacology. PMID 30321532 DOI: 10.1016/j.ejphar.2018.10.005  0.635
2018 Rohrback S, April C, Kaper F, Rivera RR, Liu CS, Siddoway B, Chun J. Submegabase copy number variations arise during cerebral cortical neurogenesis as revealed by single-cell whole-genome sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 30262650 DOI: 10.1073/Pnas.1812702115  0.787
2018 Groves A, Kihara Y, Jonnalagadda D, Rivera R, Kennedy G, Mayford M, Chun J. A Functionally Defined Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (). Eneuro. 5. PMID 30255127 DOI: 10.1523/ENEURO.0239-18.2018  0.808
2018 Moreno-Fernández RD, Nieto-Quero A, Gómez-Salas FJ, Chun J, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Pérez-Martín M, Pedraza C. Effects of genetic deletion versus pharmacological blockade of the LPA receptor on depression-like behaviour and related brain functional activity. Disease Models & Mechanisms. PMID 30061118 DOI: 10.1242/dmm.035519  0.362
2018 Rohrback S, Siddoway B, Liu CS, Chun J. Genomic mosaicism in the developing and adult brain. Developmental Neurobiology. PMID 30027562 DOI: 10.1002/Dneu.22626  0.803
2018 Magkrioti C, Oikonomou N, Kaffe E, Mouratis MA, Xylourgidis N, Barbayianni I, Megadoukas P, Harokopos V, Valavanis C, Chun J, Kosma A, Stathopoulos GT, Bouros E, Bouros D, Syrigos KN, et al. The autotaxin - lysophosphatidic acid axis promotes lung carcinogenesis. Cancer Research. PMID 29724718 DOI: 10.1158/0008-5472.CAN-17-3797  0.335
2018 Zhou B, Wolfe J, Lavelle B, Arora R, Wasserstrom JA, Chun J, Wilsbacher LD. Abstract 404: Sphingosine-1-phosphate Receptor 1 Inhibits Pathological Cardiac Remodeling Through Histone Deacetylases Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.404  0.397
2017 Lake BB, Chen S, Sos BC, Fan J, Kaeser GE, Yung YC, Duong TE, Gao D, Chun J, Kharchenko PV, Zhang K. Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain. Nature Biotechnology. PMID 29227469 DOI: 10.1038/Nbt.4038  0.799
2017 Lake BB, Codeluppi S, Yung YC, Gao D, Chun J, Kharchenko PV, Linnarsson S, Zhang K. A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA. Scientific Reports. 7: 6031. PMID 28729663 DOI: 10.1038/S41598-017-04426-W  0.805
2017 Aikawa S, Kano K, Inoue A, Wang J, Saigusa D, Nagamatsu T, Hirota Y, Fujii T, Tsuchiya S, Taketomi Y, Sugimoto Y, Murakami M, Arita M, Kurano M, Ikeda H, ... ... Chun J, et al. Autotaxin-lysophosphatidic acid-LPA3 signaling at the embryo-epithelial boundary controls decidualization pathways. The Embo Journal. PMID 28588064 DOI: 10.15252/embj.201696290  0.343
2017 Dusaban SS, Chun J, Rosen H, Purcell NH, Brown JH. Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes. Journal of Neuroinflammation. 14: 111. PMID 28577576 DOI: 10.1186/S12974-017-0882-X  0.413
2017 Moreno-Fernández RD, Pérez-Martín M, Castilla-Ortega E, Rosell Del Valle C, García-Fernández MI, Chun J, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Pedraza C. maLPA1-null mice as an endophenotype of anxious depression. Translational Psychiatry. 7: e1077. PMID 28375206 DOI: 10.1038/tp.2017.24  0.322
2017 Gaire BP, Lee CH, Sapkota A, Lee SY, Chun J, Cho HJ, Nam TG, Choi JW. Identification of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1) as a Pathogenic Factor in Transient Focal Cerebral Ischemia. Molecular Neurobiology. PMID 28343295 DOI: 10.1007/S12035-017-0468-8  0.566
2017 Dancs PT, Ruisanchez É, Balogh A, Panta CR, Miklós Z, Nüsing RM, Aoki J, Chun J, Offermanns S, Tigyi G, Benyó Z. LPA1 receptor-mediated thromboxane A2 release is responsible for lysophosphatidic acid-induced vascular smooth muscle contraction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28069828 DOI: 10.1096/fj.201600735R  0.327
2016 Yung BS, Brand CS, Xiang SY, Gray CB, Means CK, Rosen H, Chun J, Purcell N, Brown JH, Miyamoto S. Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection. Journal of Molecular and Cellular Cardiology. PMID 28017639 DOI: 10.1016/J.Yjmcc.2016.12.008  0.338
2016 Sakai N, Chun J, Duffield JS, Lagares D, Wada T, Luster AD, Tager AM. Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor. Kidney International. PMID 27927603 DOI: 10.1016/j.kint.2016.09.030  0.338
2016 Vogt J, Kirischuk S, Unichenko P, Schlüter L, Pelosi A, Endle H, Yang JW, Schmarowski N, Cheng J, Thalman C, Strauss U, Prokudin A, Bharati BS, Aoki J, Chun J, et al. Synaptic Phospholipid Signaling Modulates Axon Outgrowth via Glutamate-dependent Ca2+-mediated Molecular Pathways. Cerebral Cortex (New York, N.Y. : 1991). PMID 27909001 DOI: 10.1093/cercor/bhw370  0.316
2016 Fang V, Chaluvadi VS, Ramos-Perez WD, Mendoza A, Baeyens A, Rivera R, Chun J, Cammer M, Schwab SR. Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. Nature Immunology. PMID 27841869 DOI: 10.1038/Ni.3619  0.342
2016 Lai MK, Chew WS, Torta F, Rao A, Harris GL, Chun J, Herr DR. Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs. Neuromolecular Medicine. PMID 27393119 DOI: 10.1007/s12017-016-8424-8  0.654
2016 Lake BB, Ai R, Kaeser GE, Salathia NS, Yung YC, Liu R, Wildberg A, Gao D, Fung HL, Chen S, Vijayaraghavan R, Wong J, Chen A, Sheng X, Kaper F, ... ... Chun J, et al. Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain. Science (New York, N.Y.). 352: 1586-90. PMID 27339989 DOI: 10.1126/Science.Aaf1204  0.794
2016 Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR. Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development. Developmental Biology. PMID 27333774 DOI: 10.1016/J.Ydbio.2016.06.024  0.661
2016 Keul P, van Borren MM, Ghanem A, Müller FU, Baartscheer A, Verkerk AO, Stümpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, ... ... Chun J, et al. Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning. Journal of the American Heart Association. 5. PMID 27207969 DOI: 10.1161/Jaha.116.003393  0.623
2016 Alfonzo-Méndez MA, Castillo-Badillo JA, Romero-Ávila MT, Rivera R, Chun J, García-Sáinz JA. Carboxyl terminus-truncated α1D-adrenoceptors inhibit the ERK pathway. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 27146292 DOI: 10.1007/s00210-016-1254-2  0.343
2016 Funke M, Knudsen L, Lagares D, Ebener S, Probst CK, Fontaine BA, Franklin A, Kellner M, Kühnel M, Matthieu S, Grothausmann R, Chun J, Roberts JD, Ochs M, Tager AM. LPA Signaling Through the LPA1 Receptor is Required for Alveolarization. American Journal of Respiratory Cell and Molecular Biology. PMID 27082727 DOI: 10.1165/rcmb.2015-0152OC  0.305
2016 Herr DR, Reolo MJ, Peh YX, Wang W, Lee CW, Rivera R, Paterson IC, Chun J. Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy. Scientific Reports. 6: 24541. PMID 27080739 DOI: 10.1038/Srep24541  0.779
2016 Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J. ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Scientific Reports. 6: 23433. PMID 27005960 DOI: 10.1038/Srep23433  0.394
2016 Kitada Y, Kajita K, Taguchi K, Mori I, Yamauchi M, Ikeda T, Kawashima M, Asano M, Kajita T, Ishizuka T, Banno Y, Kojima I, Chun J, Kamata S, Ishii I, et al. Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice. Endocrinology. en20151768. PMID 26943364 DOI: 10.1210/En.2015-1768  0.583
2016 Fan J, Salathia N, Liu R, Kaeser GE, Yung YC, Herman JL, Kaper F, Fan JB, Zhang K, Chun J, Kharchenko PV. Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis. Nature Methods. PMID 26780092 DOI: 10.1038/Nmeth.3734  0.784
2015 Moon E, Han JE, Jeon S, Ryu JH, Choi JW, Chun J. Exogenous S1P Exposure Potentiates Ischemic Stroke Damage That Is Reduced Possibly by Inhibiting S1P Receptor Signaling. Mediators of Inflammation. 2015: 492659. PMID 26576074 DOI: 10.1155/2015/492659  0.526
2015 Kihara Y, Groves A, Rivera RR, Chun J. Dimethyl fumarate inhibits integrin α4 expression in multiple sclerosis models. Annals of Clinical and Translational Neurology. 2: 978-83. PMID 26478898 DOI: 10.1002/Acn3.251  0.783
2015 Chrencik JE, Roth CB, Terakado M, Kurata H, Omi R, Kihara Y, Warshaviak D, Nakade S, Asmar-Rovira G, Mileni M, Mizuno H, Griffith MT, Rodgers C, Han GW, Velasquez J, ... Chun J, et al. Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 161: 1633-43. PMID 26091040 DOI: 10.1016/J.Cell.2015.06.002  0.354
2015 González de San Román E, Manuel I, Giralt MT, Chun J, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Ferrer I, Rodríguez-Puertas R. Anatomical location of LPA1 activation and LPA phospholipid precursors in rodent and human brain. Journal of Neurochemistry. 134: 471-85. PMID 25857358 DOI: 10.1111/jnc.13112  0.415
2015 Sheng X, Yung YC, Chen A, Chun J. Lysophosphatidic acid signalling in development. Development (Cambridge, England). 142: 1390-5. PMID 25852197 DOI: 10.1242/Dev.121723  0.801
2015 Mirendil H, Thomas EA, De Loera C, Okada K, Inomata Y, Chun J. LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage. Translational Psychiatry. 5: e541. PMID 25849980 DOI: 10.1038/Tp.2015.33  0.784
2015 Yung YC, Stoddard NC, Mirendil H, Chun J. Lysophosphatidic Acid signaling in the nervous system. Neuron. 85: 669-82. PMID 25695267 DOI: 10.1016/J.Neuron.2015.01.009  0.809
2015 Bushman DM, Kaeser GE, Siddoway B, Westra JW, Rivera RR, Rehen SK, Yung YC, Chun J. Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains. Elife. 4. PMID 25650802 DOI: 10.7554/Elife.05116  0.779
2015 Stoddard NC, Chun J. Promising pharmacological directions in the world of lysophosphatidic Acid signaling. Biomolecules & Therapeutics. 23: 1-11. PMID 25593637 DOI: 10.4062/biomolther.2014.109  0.357
2015 Kihara Y, Mizuno H, Chun J. Lysophospholipid receptors in drug discovery. Experimental Cell Research. 333: 171-7. PMID 25499971 DOI: 10.1016/j.yexcr.2014.11.020  0.379
2015 Bushman DM, Kaeser GE, Siddoway B, Westra JW, Rivera RR, Rehen SK, Yung YC, Chun J. Author response: Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains Elife. DOI: 10.7554/Elife.05116.031  0.791
2014 García-Díaz B, Riquelme R, Varela-Nieto I, Jiménez AJ, de Diego I, Gómez-Conde AL, Matas-Rico E, Aguirre JA, Chun J, Pedraza C, Santín LJ, Fernández O, Rodríguez de Fonseca F, Estivill-Torrús G. Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex. Brain Structure & Function. PMID 25226845 DOI: 10.1007/s00429-014-0885-7  0.373
2014 Yung YC, Stoddard NC, Chun J. LPA receptor signaling: pharmacology, physiology, and pathophysiology. Journal of Lipid Research. 55: 1192-1214. PMID 24643338 DOI: 10.1194/Jlr.R046458  0.817
2014 Kihara Y, Maceyka M, Spiegel S, Chun J. Lysophospholipid receptor nomenclature review: IUPHAR Review 8. British Journal of Pharmacology. 171: 3575-94. PMID 24602016 DOI: 10.1111/bph.12678  0.386
2014 Wu DD, Zhang F, Hao F, Chun J, Xu X, Cui MZ. Matricellular protein Cyr61 bridges lysophosphatidic acid and integrin pathways leading to cell migration. The Journal of Biological Chemistry. 289: 5774-83. PMID 24371135 DOI: 10.1074/Jbc.M113.533042  0.356
2014 Pedraza C, Sánchez-López J, Castilla-Ortega E, Rosell-Valle C, Zambrana-Infantes E, García-Fernández M, Rodriguez de Fonseca F, Chun J, Santín LJ, Estivill-Torrús G. Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors. Brain Structure & Function. 219: 1659-72. PMID 23775489 DOI: 10.1007/s00429-013-0592-9  0.359
2013 Gole J, Gore A, Richards A, Chiu YJ, Fung HL, Bushman D, Chiang HI, Chun J, Lo YH, Zhang K. Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells. Nature Biotechnology. 31: 1126-32. PMID 24213699 DOI: 10.1038/Nbt.2720  0.796
2013 Anliker B, Choi JW, Lin ME, Gardell SE, Rivera RR, Kennedy G, Chun J. Lysophosphatidic acid (LPA) and its receptor, LPA1 , influence embryonic schwann cell migration, myelination, and cell-to-axon segregation. Glia. 61: 2009-22. PMID 24115248 DOI: 10.1002/Glia.22572  0.795
2013 Herr DR, Lee CW, Wang W, Ware A, Rivera R, Chun J. Sphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic development. The Journal of Biological Chemistry. 288: 29882-9. PMID 24003216 DOI: 10.1074/jbc.M113.510099  0.787
2013 Huang LS, Fu P, Patel P, Harijith A, Sun T, Zhao Y, Garcia JG, Chun J, Natarajan V. Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice. American Journal of Respiratory Cell and Molecular Biology. 49: 912-22. PMID 23808384 DOI: 10.1165/rcmb.2013-0070OC  0.3
2013 Ma L, Nagai J, Chun J, Ueda H. An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model. Molecular Pain. 9: 29. PMID 23773289 DOI: 10.1186/1744-8069-9-29  0.321
2013 Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, et al. Necessity of lysophosphatidic acid receptor 1 for development of arthritis. Arthritis and Rheumatism. 65: 2037-47. PMID 23666827 DOI: 10.1002/Art.37991  0.346
2013 Groves A, Kihara Y, Chun J. Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy. Journal of the Neurological Sciences. 328: 9-18. PMID 23518370 DOI: 10.1016/J.Jns.2013.02.011  0.799
2013 Lee SJ, Leoni G, Neumann PA, Chun J, Nusrat A, Yun CC. Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure. Molecular and Cellular Biology. 33: 2016-28. PMID 23478264 DOI: 10.1128/Mcb.00038-13  0.374
2013 Bushman DM, Chun J. The genomically mosaic brain: aneuploidy and more in neural diversity and disease. Seminars in Cell & Developmental Biology. 24: 357-69. PMID 23466288 DOI: 10.1016/J.Semcdb.2013.02.003  0.803
2013 Sakai N, Chun J, Duffield JS, Wada T, Luster AD, Tager AM. LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1830-46. PMID 23322166 DOI: 10.1096/fj.12-219378  0.366
2013 Choi JW, Chun J. Lysophospholipids and their receptors in the central nervous system. Biochimica Et Biophysica Acta. 1831: 20-32. PMID 22884303 DOI: 10.1016/J.Bbalip.2012.07.015  0.6
2013 Gennero I, Laurencin-Dalicieux S, Conte-Auriol F, Briand-Mesange F, Chun J, Salles J. Growth plate modifications in lysophosphatidic acid LPA1 receptor-invalidated mice Bone Abstracts. DOI: 10.1530/Boneabs.2.P125  0.316
2013 Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, et al. THU0106 Lysophosphatidic Acid Receptor LPA1 is Essential for Development of Arthritis Annals of the Rheumatic Diseases. 72: A198.3-A198. DOI: 10.1136/Annrheumdis-2013-Eular.634  0.334
2013 Mirendil H, Lin ME, Chun J. Lysophosphatidic Acid (LPA) Receptor Signaling Lysophospholipid Receptors: Signaling and Biochemistry. 1-39. DOI: 10.1002/9781118531426.ch1  0.56
2012 Peterson SE, Yang AH, Bushman DM, Westra JW, Yung YC, Barral S, Mutoh T, Rehen SK, Chun J. Aneuploid cells are differentially susceptible to caspase-mediated death during embryonic cerebral cortical development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16213-22. PMID 23152605 DOI: 10.1523/Jneurosci.3706-12.2012  0.799
2012 Lin ME, Rivera RR, Chun J. Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain. The Journal of Biological Chemistry. 287: 17608-17. PMID 22461625 DOI: 10.1074/Jbc.M111.330183  0.623
2012 Ye X, Diao H, Chun J. 11-deoxy prostaglandin F(2α), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3((-/-)) females. Fertility and Sterility. 97: 757-63. PMID 22222195 DOI: 10.1016/J.Fertnstert.2011.12.004  0.62
2012 Funke M, Zhao Z, Xu Y, Chun J, Tager AM. The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury. American Journal of Respiratory Cell and Molecular Biology. 46: 355-64. PMID 22021336 DOI: 10.1165/rcmb.2010-0155OC  0.329
2012 Castillo-Badillo JA, Molina-Muñoz T, Romero-Ávila MT, Vázquez-Macías A, Rivera R, Chun J, García-Sáinz JA. Sphingosine 1-phosphate-mediated α1B-adrenoceptor desensitization and phosphorylation. Direct and paracrine/autocrine actions. Biochimica Et Biophysica Acta. 1823: 245-54. PMID 22019450 DOI: 10.1016/j.bbamcr.2011.10.002  0.342
2012 Cheng HY, Dong A, Panchatcharam M, Mueller P, Yang F, Li Z, Mills G, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 24-32. PMID 22015657 DOI: 10.1161/Atvbaha.111.234708  0.31
2012 Mutoh T, Rivera R, Chun J. Insights into the pharmacological relevance of lysophospholipid receptors. British Journal of Pharmacology. 165: 829-44. PMID 21838759 DOI: 10.1111/j.1476-5381.2011.01622.x  0.385
2011 Akahoshi N, Ishizaki Y, Yasuda H, Murashima YL, Shinba T, Goto K, Himi T, Chun J, Ishii I. Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2. Epilepsy & Behavior : E&B. 22: 659-65. PMID 22019019 DOI: 10.1016/J.Yebeh.2011.09.002  0.591
2011 Castilla-Ortega E, Hoyo-Becerra C, Pedraza C, Chun J, Rodríguez De Fonseca F, Estivill-Torrús G, Santín LJ. Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice. Plos One. 6: e25522. PMID 21980482 DOI: 10.1371/journal.pone.0025522  0.312
2011 Yung YC, Mutoh T, Lin ME, Noguchi K, Rivera RR, Choi JW, Kingsbury MA, Chun J. Lysophosphatidic acid signaling may initiate fetal hydrocephalus. Science Translational Medicine. 3: 99ra87. PMID 21900594 DOI: 10.1126/Scitranslmed.3002095  0.815
2011 Herr KJ, Herr DR, Lee CW, Noguchi K, Chun J. Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: 15444-9. PMID 21878565 DOI: 10.1073/Pnas.1106129108  0.818
2011 Peterson SE, Westra JW, Rehen SK, Young H, Bushman DM, Paczkowski CM, Yung YC, Lynch CL, Tran HT, Nickey KS, Wang YC, Laurent LC, Loring JF, Carpenter MK, Chun J. Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy. Plos One. 6: e23018. PMID 21857983 DOI: 10.1371/Journal.Pone.0023018  0.782
2011 Peterson SE, Chun J, Loring J. FISH analysis of human pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 767: 191-200. PMID 21822876 DOI: 10.1007/978-1-61779-201-4_14  0.686
2011 Zhao J, He D, Su Y, Berdyshev E, Chun J, Natarajan V, Zhao Y. Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L547-56. PMID 21821728 DOI: 10.1152/ajplung.00058.2011  0.317
2011 Zhou Z, Subramanian P, Sevilmis G, Globke B, Soehnlein O, Karshovska E, Megens R, Heyll K, Chun J, Saulnier-Blache JS, Reinholz M, van Zandvoort M, Weber C, Schober A. Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium. Cell Metabolism. 13: 592-600. PMID 21531341 DOI: 10.1016/j.cmet.2011.02.016  0.314
2011 Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines. Journal of Lipid Research. 52: 1307-18. PMID 21521824 DOI: 10.1194/jlr.M008045  0.347
2011 Cohen JA, Chun J. Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. Annals of Neurology. 69: 759-77. PMID 21520239 DOI: 10.1002/ana.22426  0.305
2011 Ye X, Herr DR, Diao H, Rivera R, Chun J. Unique uterine localization and regulation may differentiate LPA3 from other lysophospholipid receptors for its role in embryo implantation. Fertility and Sterility. 95: 2107-13, 2113.e1-4. PMID 21411082 DOI: 10.1016/J.Fertnstert.2011.02.024  0.762
2011 Soliven B, Miron V, Chun J. The neurobiology of sphingosine 1-phosphate signaling and sphingosine 1-phosphate receptor modulators. Neurology. 76: S9-14. PMID 21339490 DOI: 10.1212/WNL.0b013e31820d9507  0.399
2011 Castelino FV, Seiders J, Bain G, Brooks SF, King CD, Swaney JS, Lorrain DS, Chun J, Luster AD, Tager AM. Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis and Rheumatism. 63: 1405-15. PMID 21305523 DOI: 10.1002/art.30262  0.309
2011 Hopson KP, Truelove J, Chun J, Wang Y, Waeber C. S1P activates store-operated calcium entry via receptor- and non-receptor-mediated pathways in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 300: C919-26. PMID 21270296 DOI: 10.1152/ajpcell.00350.2010  0.358
2011 Choi JW, Gardell SE, Herr DR, Rivera R, Lee CW, Noguchi K, Teo ST, Yung YC, Lu M, Kennedy G, Chun J. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation. Proceedings of the National Academy of Sciences of the United States of America. 108: 751-6. PMID 21177428 DOI: 10.1073/Pnas.1014154108  0.799
2011 Noguchi K, Chun J. Roles for lysophospholipid S1P receptors in multiple sclerosis. Critical Reviews in Biochemistry and Molecular Biology. 46: 2-10. PMID 20979571 DOI: 10.3109/10409238.2010.522975  0.757
2011 Diao H, Aplin JD, Xiao S, Chun J, Li Z, Chen S, Ye X. Altered spatiotemporal expression of collagen types I, III, IV, and VI in Lpar3-deficient peri-implantation mouse uterus. Biology of Reproduction. 84: 255-65. PMID 20864640 DOI: 10.1095/Biolreprod.110.086942  0.623
2011 Lee S, Chun J, Yun C. Lysophosphatidic Acid Receptor Type 1 Plays a Crucial Role in Migration of Epithelial Cells in the Intestine Gastroenterology. 140: S-655. DOI: 10.1016/S0016-5085(11)62716-9  0.341
2010 Birgbauer E, Chun J. Lysophospholipid receptors LPA1-3 are not required for the inhibitory effects of LPA on mouse retinal growth cones. Eye and Brain. 2: 1-13. PMID 26966392 DOI: 10.2147/EB.S7666  0.786
2010 Chun J, Hla T, Lynch KR, Spiegel S, Moolenaar WH. International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature. Pharmacological Reviews. 62: 579-87. PMID 21079037 DOI: 10.1124/Pr.110.003111  0.42
2010 Lee CW, Choi JW, Chun J. Neurological S1P signaling as an emerging mechanism of action of oral FTY720 (fingolimod) in multiple sclerosis. Archives of Pharmacal Research. 33: 1567-74. PMID 21052934 DOI: 10.1007/S12272-010-1008-5  0.728
2010 Westra JW, Rivera RR, Bushman DM, Yung YC, Peterson SE, Barral S, Chun J. Neuronal DNA content variation (DCV) with regional and individual differences in the human brain. The Journal of Comparative Neurology. 518: 3981-4000. PMID 20737596 DOI: 10.1002/Cne.22436  0.791
2010 Lin S, Lee SJ, Shim H, Chun J, Yun CC. The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1128-38. PMID 20724530 DOI: 10.1152/ajpgi.00321.2010  0.317
2010 Dubin AE, Herr DR, Chun J. Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7300-9. PMID 20505096 DOI: 10.1523/JNEUROSCI.6151-09.2010  0.809
2010 Xie W, Uchida H, Nagai J, Ueda M, Chun J, Ueda H. Calpain-mediated down-regulation of myelin-associated glycoprotein in lysophosphatidic acid-induced neuropathic pain. Journal of Neurochemistry. 113: 1002-11. PMID 20420580 DOI: 10.1111/j.1471-4159.2010.06664.x  0.301
2010 Lin ME, Herr DR, Chun J. Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance. Prostaglandins & Other Lipid Mediators. 91: 130-8. PMID 20331961 DOI: 10.1016/J.Prostaglandins.2009.02.002  0.756
2010 Diao H, Xiao S, Cui J, Chun J, Xu Y, Ye X. Progesterone receptor-mediated up-regulation of transthyretin in preimplantation mouse uterus. Fertility and Sterility. 93: 2750-3. PMID 20188365 DOI: 10.1016/J.Fertnstert.2010.01.009  0.656
2010 Shea BS, Brooks SF, Fontaine BA, Chun J, Luster AD, Tager AM. Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury. American Journal of Respiratory Cell and Molecular Biology. 43: 662-73. PMID 20081052 DOI: 10.1165/rcmb.2009-0345OC  0.302
2010 Chun J, Hartung HP. Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis. Clinical Neuropharmacology. 33: 91-101. PMID 20061941 DOI: 10.1097/WNF.0b013e3181cbf825  0.376
2010 Imasawa T, Koike K, Ishii I, Chun J, Yatomi Y. Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells. Biochemical and Biophysical Research Communications. 392: 207-11. PMID 20060809 DOI: 10.1016/J.Bbrc.2010.01.016  0.605
2010 Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J. LPA receptors: subtypes and biological actions. Annual Review of Pharmacology and Toxicology. 50: 157-86. PMID 20055701 DOI: 10.1146/Annurev.Pharmtox.010909.105753  0.799
2010 Ye X, Chun J. Lysophosphatidic acid (LPA) signaling in vertebrate reproduction. Trends in Endocrinology and Metabolism: Tem. 21: 17-24. PMID 19836970 DOI: 10.1016/J.Tem.2009.08.003  0.678
2010 Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, Banno Y, Sasaki M, Ichi I, Okamura M, ... ... Chun J, et al. S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species. Cardiovascular Research. 85: 484-93. PMID 19755413 DOI: 10.1093/Cvr/Cvp312  0.604
2010 Chun J, Westra JW, Bushman D. A reply to Iourov et al Neurodegenerative Diseases. 8: 38-40. DOI: 10.1159/000315399  0.749
2009 Zhao Y, Tong J, He D, Pendyala S, Evgeny B, Chun J, Sperling AI, Natarajan V. Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma. Respiratory Research. 10: 114. PMID 19930563 DOI: 10.1186/1465-9921-10-114  0.335
2009 Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Roots CM, Beilke JN, Banerjee A, Reiner SL, Miller SA, Weinmann AS, Goodnow CC, Lanier LL, ... ... Chun J, et al. T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. The Journal of Experimental Medicine. 206: 2469-81. PMID 19808259 DOI: 10.1084/Jem.20090525  0.316
2009 Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, ... ... Chun J, et al. Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell. 138: 1222-35. PMID 19766573 DOI: 10.1016/J.Cell.2009.06.050  0.368
2009 Westra JW, Barral S, Chun J. A reevaluation of tetraploidy in the Alzheimer's disease brain. Neuro-Degenerative Diseases. 6: 221-9. PMID 19738367 DOI: 10.1159/000236901  0.764
2009 Teo ST, Yung YC, Herr DR, Chun J. Lysophosphatidic acid in vascular development and disease. Iubmb Life. 61: 791-9. PMID 19621353 DOI: 10.1002/Iub.220  0.795
2009 McConnell MJ, MacMillan HR, Chun J. Mathematical modeling supports substantial mouse neural progenitor cell death. Neural Development. 4: 28. PMID 19602274 DOI: 10.1186/1749-8104-4-28  0.698
2009 Yung YC, Kennedy G, Chun J. Identification of neural programmed cell death through the detection of DNA fragmentation in situ and by PCR. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 3.8. PMID 19575470 DOI: 10.1002/0471142301.ns0308s48  0.78
2009 Nieuwenhuis B, Lüth A, Chun J, Huwiler A, Pfeilschifter J, Schäfer-Korting M, Kleuser B. Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P(3) in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone. Journal of Molecular Medicine (Berlin, Germany). 87: 645-57. PMID 19370318 DOI: 10.1007/s00109-009-0468-x  0.342
2009 Noguchi K, Herr D, Mutoh T, Chun J. Lysophosphatidic acid (LPA) and its receptors. Current Opinion in Pharmacology. 9: 15-23. PMID 19119080 DOI: 10.1016/J.Coph.2008.11.010  0.813
2009 Ikeda H, Watanabe N, Ishii I, Shimosawa T, Kume Y, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Iitsuka S, Fujita R, Omata M, Chun J, Yatomi Y. Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. Journal of Lipid Research. 50: 556-64. PMID 18955732 DOI: 10.1194/Jlr.M800496-Jlr200  0.588
2009 Jawaid A, Rademakers R, Kass JS, Kalkonde Y, Okochi M, Tagami S, Nishitomi K, Nef T, Quinter G, Isobe C, Abe T, Portelius E, Zhang B, Benetin J, Zerr I, ... ... Chun J, et al. Contents Vol. 6, 2009 Neurodegenerative Diseases. 6. DOI: 10.1159/000278750  0.703
2009 Jawaid A, Rademakers R, Kass JS, Kalkonde Y, Okochi M, Tagami S, Nishitomi K, Nef T, Quinter G, Isobe C, Abe T, Portelius E, Zhang B, Benetin J, Zerr I, ... ... Chun J, et al. Subject Index Vol. 6, 2009 Neurodegenerative Diseases. 6: 282-282. DOI: 10.1159/000278749  0.698
2009 Ye X, Chun J, Xiao S, Diao H. Potential Biomarkers for Uterine Receptivity in LPA3-Deficient Females. Biology of Reproduction. 81: 411-411. DOI: 10.1093/Biolreprod/81.S1.411  0.589
2009 Huh S, Kim N, Sun Y, Oh S, Kim S, Hwang J, Contos J, Chun J. Involvement of E-protein, HEB, in transcriptional repression of the mouse lysophosphatidic acid receptor-1 gene expression in neocortical neuroblast cells Neuroscience Research. 65: S89. DOI: 10.1016/j.neures.2009.09.360  0.371
2008 Xie W, Matsumoto M, Chun J, Ueda H. Involvement of LPA1 receptor signaling in the reorganization of spinal input through Abeta-fibers in mice with partial sciatic nerve injury. Molecular Pain. 4: 46. PMID 18854053 DOI: 10.1186/1744-8069-4-46  0.309
2008 Mutoh T, Chun J. Lysophospholipid activation of G protein-coupled receptors. Sub-Cellular Biochemistry. 49: 269-97. PMID 18751915 DOI: 10.1007/978-1-4020-8831-5_10  0.401
2008 Matas-Rico E, García-Diaz B, Llebrez-Zayas P, López-Barroso D, Santín L, Pedraza C, Smith-Fernández A, Fernández-Llebrez P, Tellez T, Redondo M, Chun J, De Fonseca FR, Estivill-Torrús G. Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus. Molecular and Cellular Neurosciences. 39: 342-55. PMID 18708146 DOI: 10.1016/j.mcn.2008.07.014  0.416
2008 Panchatcharam M, Miriyala S, Yang F, Rojas M, End C, Vallant C, Dong A, Lynch K, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Circulation Research. 103: 662-70. PMID 18703779 DOI: 10.1161/Circresaha.108.180778  0.33
2008 Ye X, Skinner MK, Kennedy G, Chun J. Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling. Biology of Reproduction. 79: 328-36. PMID 18448840 DOI: 10.1095/Biolreprod.108.068783  0.689
2008 Choi JW, Lee CW, Chun J. Biological roles of lysophospholipid receptors revealed by genetic null mice: an update. Biochimica Et Biophysica Acta. 1781: 531-9. PMID 18407842 DOI: 10.1016/J.Bbalip.2008.03.004  0.741
2008 Peterson SE, Westra JW, Paczkowski CM, Chun J. Chromosomal mosaicism in neural stem cells. Methods in Molecular Biology (Clifton, N.J.). 438: 197-204. PMID 18369759 DOI: 10.1007/978-1-59745-133-8_16  0.788
2008 Niessen F, Schaffner F, Furlan-Freguia C, Pawlinski R, Bhattacharjee G, Chun J, Derian CK, Andrade-Gordon P, Rosen H, Ruf W. Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. Nature. 452: 654-8. PMID 18305483 DOI: 10.1038/Nature06663  0.364
2008 Means CK, Miyamoto S, Chun J, Brown JH. S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses. The Journal of Biological Chemistry. 283: 11954-63. PMID 18296752 DOI: 10.1074/Jbc.M707422200  0.36
2008 Inoue M, Xie W, Matsushita Y, Chun J, Aoki J, Ueda H. Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid. Neuroscience. 152: 296-298. PMID 18280050 DOI: 10.1016/J.Neuroscience.2007.12.041  0.33
2008 Westra JW, Peterson SE, Yung YC, Mutoh T, Barral S, Chun J. Aneuploid mosaicism in the developing and adult cerebellar cortex. The Journal of Comparative Neurology. 507: 1944-51. PMID 18273885 DOI: 10.1002/Cne.21648  0.808
2008 Spohr TC, de Sampaio E Spohr TC, Choi JW, Gardell SE, Herr DR, Rehen SK, Gomes FC, Chun J. Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation. The Journal of Biological Chemistry. 283: 7470-9. PMID 18198181 DOI: 10.1074/Jbc.M707758200  0.824
2008 Lee CW, Kim NH, Choi HK, Sun Y, Nam JS, Rhee HJ, Chun J, Huh SO. Lysophosphatidic acid-induced c-fos up-regulation involves cyclic AMP response element-binding protein activated by mitogen- and stress-activated protein kinase-1. Journal of Cellular Biochemistry. 104: 785-94. PMID 18172855 DOI: 10.1002/Jcb.21663  0.647
2008 Shano S, Moriyama R, Chun J, Fukushima N. Lysophosphatidic acid stimulates astrocyte proliferation through LPA1. Neurochemistry International. 52: 216-20. PMID 17692995 DOI: 10.1016/J.Neuint.2007.07.004  0.646
2008 Estivill-Torrús G, Llebrez-Zayas P, Matas-Rico E, Santín L, Pedraza C, De Diego I, Del Arco I, Fernández-Llebrez P, Chun J, De Fonseca FR. Absence of LPA1 signaling results in defective cortical development. Cerebral Cortex (New York, N.Y. : 1991). 18: 938-50. PMID 17656621 DOI: 10.1093/cercor/bhm132  0.409
2008 Ye X, Chun J. Lysophosphatidic Acid Receptor-Specific Functions in Uterine Receptivity and Spermatogenesis. Biology of Reproduction. 78: 201-201. DOI: 10.1093/Biolreprod/78.S1.201  0.662
2007 Salomone S, Potts EM, Tyndall S, Ip PC, Chun J, Brinkmann V, Waeber C. Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools. British Journal of Pharmacology. 153: 140-7. PMID 18026125 DOI: 10.1038/sj.bjp.0707581  0.313
2007 Pradère JP, Klein J, Grès S, Guigné C, Neau E, Valet P, Calise D, Chun J, Bascands JL, Saulnier-Blache JS, Schanstra JP. LPA1 receptor activation promotes renal interstitial fibrosis. Journal of the American Society of Nephrology : Jasn. 18: 3110-8. PMID 18003779 DOI: 10.1681/ASN.2007020196  0.306
2007 Hama K, Aoki J, Inoue A, Endo T, Amano T, Motoki R, Kanai M, Ye X, Chun J, Matsuki N, Suzuki H, Shibasaki M, Arai H. Embryo spacing and implantation timing are differentially regulated by LPA3-mediated lysophosphatidic acid signaling in mice. Biology of Reproduction. 77: 954-9. PMID 17823089 DOI: 10.1095/Biolreprod.107.060293  0.631
2007 Chan LC, Peters W, Xu Y, Chun J, Farese RV, Cases S. LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA). Journal of Leukocyte Biology. 82: 1193-200. PMID 17709403 DOI: 10.1189/jlb.0407221  0.362
2007 Rajendran RS, Zupanc MM, Lösche A, Westra J, Chun J, Zupanc GK. Numerical chromosome variation and mitotic segregation defects in the adult brain of teleost fish. Developmental Neurobiology. 67: 1334-47. PMID 17638379 DOI: 10.1002/Dneu.20365  0.767
2007 Means CK, Xiao CY, Li Z, Zhang T, Omens JH, Ishii I, Chun J, Brown JH. Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2944-51. PMID 17293497 DOI: 10.1152/Ajpheart.01331.2006  0.624
2007 Herr DR, Grillet N, Schwander M, Rivera R, Müller U, Chun J. Sphingosine 1-phosphate (S1P) signaling is required for maintenance of hair cells mainly via activation of S1P2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1474-8. PMID 17287522 DOI: 10.1523/JNEUROSCI.4245-06.2007  0.67
2007 Keller CD, Rivera Gil P, Tölle M, van der Giet M, Chun J, Radeke HH, Schäfer-Korting M, Kleuser B. Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling. The American Journal of Pathology. 170: 281-92. PMID 17200201 DOI: 10.2353/ajpath.2007.060485  0.346
2007 Lee CW, Rivera R, Dubin AE, Chun J. LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation. The Journal of Biological Chemistry. 282: 4310-7. PMID 17166850 DOI: 10.1074/Jbc.M610826200  0.814
2007 Walter DH, Rochwalsky U, Reinhold J, Seeger F, Aicher A, Urbich C, Spyridopoulos I, Chun J, Brinkmann V, Keul P, Levkau B, Zeiher AM, Dimmeler S, Haendeler J. Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 275-82. PMID 17158356 DOI: 10.1161/01.ATV.0000254669.12675.70  0.371
2007 Fukushima N, Shano S, Moriyama R, Chun J. Lysophosphatidic acid stimulates neuronal differentiation of cortical neuroblasts through the LPA1-G(i/o) pathway. Neurochemistry International. 50: 302-7. PMID 17056154 DOI: 10.1016/J.Neuint.2006.09.008  0.641
2007 Rivera R, Chun J. Potential therapeutic roles of lysophospholipid signaling in autoimmune-related disease Future Lipidology. 2: 535-545. DOI: 10.2217/17460875.2.5.535  0.403
2007 Ye X, Chun. J. MECHANISM OF LYSOPHOSPHOLIPID RECEPTORSPECIFIC FUNCTION IN EMBRYO IMPLANTATION Biology of Reproduction. 77: 234-234. DOI: 10.1093/Biolreprod/77.S1.234  0.564
2007 Ninose S, Shano S, Moriyama R, Chun J, Fukushima N. Lysophosphatidic acid stimulates neuronal differentiation through LPA1 Neuroscience Research. 58: S143. DOI: 10.1016/J.Neures.2007.06.1410  0.594
2007 Peterson S, Rehen S, Westra W, Yung Y, Chun J. Spectral Karyotyping and Fluorescent in Situ Hybridization Human Stem Cell Manual. 71-84. DOI: 10.1016/B978-012370465-8/50011-9  0.758
2006 Rivera R, Chun J. Biological effects of lysophospholipids. Reviews of Physiology Biochemistry and Pharmacology. 160: 25-46. PMID 18481029 DOI: 10.1007/112_0507  0.446
2006 Birgbauer E, Chun J. New developments in the biological functions of lysophospholipids Cellular and Molecular Life Sciences. 63: 2695-2701. PMID 16988788 DOI: 10.1007/s00018-006-6155-y  0.816
2006 Kingsbury MA, Yung YC, Peterson SE, Westra JW, Chun J. Aneuploidy in the normal and diseased brain. Cellular and Molecular Life Sciences : Cmls. 63: 2626-41. PMID 16952055 DOI: 10.1007/S00018-006-6169-5  0.802
2006 Rehen SK, Kingsbury MA, Almeida BS, Herr DR, Peterson S, Chun J. A new method of embryonic culture for assessing global changes in brain organization. Journal of Neuroscience Methods. 158: 100-8. PMID 16824613 DOI: 10.1016/J.Jneumeth.2006.05.025  0.795
2006 Lee CW, Rivera R, Gardell S, Dubin AE, Chun J. GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5. The Journal of Biological Chemistry. 281: 23589-97. PMID 16774927 DOI: 10.1074/Jbc.M603670200  0.82
2006 Chao C, Herr D, Chun J, Xu Y. Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression. The Embo Journal. 25: 2615-22. PMID 16757976 DOI: 10.1038/Sj.Emboj.7601167  0.64
2006 Chun J, Rosen H. Lysophospholipid receptors as potential drug targets in tissue transplantation and autoimmune diseases. Current Pharmaceutical Design. 12: 161-71. PMID 16454733 DOI: 10.2174/138161206775193109  0.401
2006 Gardell SE, Dubin AE, Chun J. Emerging medicinal roles for lysophospholipid signaling. Trends in Molecular Medicine. 12: 65-75. PMID 16406843 DOI: 10.1016/J.Molmed.2005.12.001  0.796
2005 Chun J. Lysophospholipids in the nervous system Prostaglandins and Other Lipid Mediators. 77: 46-51. PMID 16099390 DOI: 10.1016/j.prostaglandins.2004.09.009  0.328
2005 Gon Y, Wood MR, Kiosses WB, Jo E, Sanna MG, Chun J, Rosen H. S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF Proceedings of the National Academy of Sciences of the United States of America. 102: 9270-9275. PMID 15968000 DOI: 10.1073/Pnas.0501997102  0.315
2005 Ye X, Hama K, Contos JJ, Anliker B, Inoue A, Skinner MK, Suzuki H, Amano T, Kennedy G, Arai H, Aoki J, Chun J. LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing. Nature. 435: 104-8. PMID 15875025 DOI: 10.1038/Nature03505  0.778
2005 Goparaju SK, Jolly PS, Watterson KR, Bektas M, Alvarez S, Sarkar S, Mel L, Ishii I, Chun J, Milstien S, Spiegel S. The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation. Molecular and Cellular Biology. 25: 4237-49. PMID 15870293 DOI: 10.1128/Mcb.25.10.4237-4249.2005  0.627
2005 Kingsbury MA, Friedman B, McConnell MJ, Rehen SK, Yang AH, Kaushal D, Chun J. Aneuploid neurons are functionally active and integrated into brain circuitry. Proceedings of the National Academy of Sciences of the United States of America. 102: 6143-7. PMID 15837924 DOI: 10.1073/Pnas.0408171102  0.81
2005 Tölle M, Levkau B, Keul P, Brinkmann V, Giebing G, Schönfelder G, Schäfers M, von Wnuck Lipinski K, Jankowski J, Jankowski V, Chun J, Zidek W, Van der Giet M. Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3. Circulation Research. 96: 913-20. PMID 15802614 DOI: 10.1161/01.RES.0000164321.91452.00  0.326
2005 Rehen SK, Yung YC, McCreight MP, Kaushal D, Yang AH, Almeida BS, Kingsbury MA, Cabral KM, McConnell MJ, Anliker B, Fontanoz M, Chun J. Constitutional aneuploidy in the normal human brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2176-80. PMID 15745943 DOI: 10.1523/Jneurosci.4560-04.2005  0.798
2005 Simon MF, Daviaud D, Pradère JP, Grès S, Guigné C, Wabitsch M, Chun J, Valet P, Saulnier-Blache JS. Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2. The Journal of Biological Chemistry. 280: 14656-62. PMID 15710620 DOI: 10.1074/jbc.M412585200  0.412
2005 Li H, Ye X, Mahanivong C, Bian D, Chun J, Huang S. Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. The Journal of Biological Chemistry. 280: 10564-71. PMID 15653692 DOI: 10.1074/Jbc.M412152200  0.646
2004 Girkontaite I, Sakk V, Wagner M, Borggrefe T, Tedford K, Chun J, Fischer KD. The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization. The Journal of Experimental Medicine. 200: 1491-501. PMID 15583019 DOI: 10.1084/jem.20041483  0.362
2004 McConnell MJ, Kaushal D, Yang AH, Kingsbury MA, Rehen SK, Treuner K, Helton R, Annas EG, Chun J, Barlow C. Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8090-6. PMID 15371510 DOI: 10.1523/Jneurosci.2263-04.2004  0.8
2004 Anliker B, Chun J. Cell surface receptors in lysophospholipid signaling. Seminars in Cell & Developmental Biology. 15: 457-65. PMID 15271291 DOI: 10.1016/J.Semcdb.2004.05.005  0.803
2004 Webb M, Tham CS, Lin FF, Lariosa-Willingham K, Yu N, Hale J, Mandala S, Chun J, Rao TS. Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice Journal of Neuroimmunology. 153: 108-121. PMID 15265669 DOI: 10.1016/j.jneuroim.2004.04.015  0.325
2004 Kingsbury MA, Rehen SK, Ye X, Chun J. Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis. Journal of Cellular Biochemistry. 92: 1004-12. PMID 15258921 DOI: 10.1002/Jcb.20061  0.777
2004 Inoue M, Rashid MH, Fujita R, Contos JJ, Chun J, Ueda H. Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling. Nature Medicine. 10: 712-8. PMID 15195086 DOI: 10.1038/nm1060  0.338
2004 Ishii I, Fukushima N, Ye X, Chun J. Lysophospholipid receptors: signaling and biology. Annual Review of Biochemistry. 73: 321-54. PMID 15189145 DOI: 10.1146/Annurev.Biochem.73.011303.073731  0.806
2004 Rao TS, Lariosa-Willingham KD, Lin FF, Yu N, Tham CS, Chun J, Webb M. Growth factor pre-treatment differentially regulates phosphoinositide turnover downstream of lysophospholipid receptor and metabotropic glutamate receptors in cultured rat cerebrocortical astrocytes International Journal of Developmental Neuroscience. 22: 131-135. PMID 15140466 DOI: 10.1016/j.ijdevneu.2004.03.005  0.386
2004 Chun J. Choices, choices, choices Nature Neuroscience. 7: 323-325. PMID 15048118 DOI: 10.1038/nn0404-323  0.304
2004 Anliker B, Chun J. Lysophospholipid G protein-coupled receptors. The Journal of Biological Chemistry. 279: 20555-8. PMID 15023998 DOI: 10.1074/Jbc.R400013200  0.791
2004 Nofer JR, van der Giet M, Tölle M, Wolinska I, von Wnuck Lipinski K, Baba HA, Tietge UJ, Gödecke A, Ishii I, Kleuser B, Schäfers M, Fobker M, Zidek W, Assmann G, Chun J, et al. HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3. The Journal of Clinical Investigation. 113: 569-81. PMID 14966566 DOI: 10.1172/Jci18004  0.606
2004 Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, Ohta H, Yamori T, Watanabe M, Chun J, Arai H. Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. The Journal of Biological Chemistry. 279: 17634-9. PMID 14744855 DOI: 10.1074/JBC.M313927200  0.355
2004 Sanna MG, Liao J, Jo E, Alfonso C, Ahn MY, Peterson MS, Webb B, Lefebvre S, Chun J, Gray N, Rosen H. Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate. The Journal of Biological Chemistry. 279: 13839-48. PMID 14732717 DOI: 10.1074/Jbc.M311743200  0.363
2004 Baudhuin LM, Jiang Y, Zaslavsky A, Ishii I, Chun J, Xu Y. S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 341-3. PMID 14657000 DOI: 10.1096/Fj.03-0302Fje  0.623
2004 Inoue M, Rashid MH, Fujita R, Contos JJA, Chun J, Ueda H. Erratum: Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling Nature Medicine. 10: 755-755. DOI: 10.1038/NM0704-755C  0.308
2003 Kingsbury MA, Rehen SK, Contos JJ, Higgins CM, Chun J. Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding. Nature Neuroscience. 6: 1292-9. PMID 14625558 DOI: 10.1038/Nn1157  0.786
2003 Yang AH, Kaushal D, Rehen SK, Kriedt K, Kingsbury MA, McConnell MJ, Chun J. Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10454-62. PMID 14614104 DOI: 10.1523/Jneurosci.23-32-10454.2003  0.803
2003 Rao TS, Lariosa-Willingham KD, Lin FF, Palfreyman EL, Yu N, Chun J, Webb M. Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes Brain Research. 990: 182-194. PMID 14568343 DOI: 10.1016/S0006-8993(03)03527-3  0.376
2003 Olivera A, Rosenfeldt HM, Bektas M, Wang F, Ishii I, Chun J, Milstien S, Spiegel S. Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. The Journal of Biological Chemistry. 278: 46452-60. PMID 12963721 DOI: 10.1074/Jbc.M308749200  0.648
2003 Kaushal D, Contos JJ, Treuner K, Yang AH, Kingsbury MA, Rehen SK, McConnell MJ, Okabe M, Barlow C, Chun J. Alteration of gene expression by chromosome loss in the postnatal mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5599-606. PMID 12843262 DOI: 10.1523/Jneurosci.23-13-05599.2003  0.812
2003 Liu H, Toman RE, Goparaju SK, Maceyka M, Nava VE, Sankala H, Payne SG, Bektas M, Ishii I, Chun J, Milstien S, Spiegel S. Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis. The Journal of Biological Chemistry. 278: 40330-6. PMID 12835323 DOI: 10.1074/Jbc.M304455200  0.58
2003 Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 100: 6777-82. PMID 12748381 DOI: 10.1073/Pnas.1131928100  0.795
2002 Ye X, Ishii I, Kingsbury MA, Chun J. Lysophosphatidic acid as a novel cell survival/apoptotic factor. Biochimica Et Biophysica Acta. 1585: 108-13. PMID 12531543 DOI: 10.1016/S1388-1981(02)00330-X  0.807
2002 Ye X, Fukushima N, Kingsbury MA, Chun J. Lysophosphatidic acid in neural signaling. Neuroreport. 13: 2169-75. PMID 12488791 DOI: 10.1097/00001756-200212030-00002  0.825
2002 Fukushima N, Ye X, Chun J. Neurobiology of lysophosphatidic acid signaling Neuroscientist. 8: 540-550. PMID 12467376 DOI: 10.1177/1073858402238513  0.778
2002 McGiffert C, Contos JJ, Friedman B, Chun J. Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis. Febs Letters. 531: 103-8. PMID 12401212 DOI: 10.1016/S0014-5793(02)03404-X  0.801
2002 Contos JJ, Ye X, Sah VP, Chun J. Tandem genomic arrangement of a G protein (Gna15) and G protein-coupled receptor (s1p(4)/lp(C1)/Edg6) gene. Febs Letters. 531: 99-102. PMID 12401211 DOI: 10.1016/S0014-5793(02)03409-9  0.673
2002 Contos JJ, Ishii I, Fukushima N, Kingsbury MA, Ye X, Kawamura S, Brown JH, Chun J. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Molecular and Cellular Biology. 22: 6921-9. PMID 12215548 DOI: 10.1128/Mcb.22.19.6921-6929.2002  0.813
2002 Fukushima N, Ishii I, Habara Y, Allen CB, Chun J. Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rho. Molecular Biology of the Cell. 13: 2692-705. PMID 12181339 DOI: 10.1091/Mbc.01-09-0465  0.744
2002 Fukushima N, Weiner JA, Kaushal D, Contos JJ, Rehen SK, Kingsbury MA, Kim KY, Chun J. Lysophosphatidic acid influences the morphology and motility of young, postmitotic cortical neurons. Molecular and Cellular Neurosciences. 20: 271-82. PMID 12093159 DOI: 10.1006/Mcne.2002.1123  0.806
2002 Yang AH, Ishii I, Chun J. In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice. Biochimica Et Biophysica Acta. 1582: 197-203. PMID 12069829 DOI: 10.1016/S1388-1981(02)00172-5  0.736
2002 Chun J, Goetzl EJ, Hla T, Igarashi Y, Lynch KR, Moolenaar W, Pyne S, Tigyi G. International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacological Reviews. 54: 265-9. PMID 12037142 DOI: 10.1124/Pr.54.2.265  0.4
2002 Ishii I, Ye X, Friedman B, Kawamura S, Contos JJ, Kingsbury MA, Yang AH, Zhang G, Brown JH, Chun J. Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3. The Journal of Biological Chemistry. 277: 25152-9. PMID 12006579 DOI: 10.1074/Jbc.M200137200  0.797
2002 Ishii I, Chun J. Anandamide-induced neuroblastoma cell rounding via the CBI cannabinoid receptors Neuroreport. 13: 593-596. PMID 11973452 DOI: 10.1097/00001756-200204160-00011  0.639
2002 Rehen SK, McConnell MJ, Kaushal D, Kingsbury MA, Yang AH, Chun J. Genetic Mosaicism in the Brain: A New Paradigm for Neuronal Diversity Directions in Science. 1: 53-55. DOI: 10.1100/Tsw.2002.199  0.79
2001 Chun J, Blaschke AJ. Identification of neural programmed cell death through the detection of DNA fragmentation in situ and by PCR Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. PMID 18428472 DOI: 10.1002/0471142301.Ns0308S00  0.305
2001 Rehen SK, McConnell MJ, Kaushal D, Kingsbury MA, Yang AH, Chun J. Chromosomal variation in neurons of the developing and adult mammalian nervous system. Proceedings of the National Academy of Sciences of the United States of America. 98: 13361-6. PMID 11698687 DOI: 10.1073/Pnas.231487398  0.799
2001 Ishii I, Friedman B, Ye X, Kawamura S, McGiffert C, Contos JJ, Kingsbury MA, Zhang G, Brown JH, Chun J. Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. The Journal of Biological Chemistry. 276: 33697-704. PMID 11443127 DOI: 10.1074/Jbc.M104441200  0.776
2001 Möller T, Contos JJ, Musante DB, Chun J, Ransom BR. Expression and function of lysophosphatidic acid receptors in cultured rodent microglial cells. The Journal of Biological Chemistry. 276: 25946-52. PMID 11340076 DOI: 10.1074/jbc.M102691200  0.352
2001 Fukushima N, Chun J. The LPA receptors Prostaglandins and Other Lipid Mediators. 64: 21-32. PMID 11324705 DOI: 10.1016/S0090-6980(01)00105-8  0.656
2001 Kimura Y, Schmitt A, Fukushima N, Ishii I, Kimura H, Nebreda AR, Chun J. Two novel Xenopus homologs of mammalian LP(A1)/EDG-2 function as lysophosphatidic acid receptors in Xenopus oocytes and mammalian cells. The Journal of Biological Chemistry. 276: 15208-15. PMID 11278944 DOI: 10.1074/Jbc.M011588200  0.753
2001 Fukushima N, Ishii I, Contos JJ, Weiner JA, Chun J. Lysophospholipid receptors. Annual Review of Pharmacology and Toxicology. 41: 507-34. PMID 11264467 DOI: 10.1146/annurev.pharmtox.41.1.507  0.574
2001 Contos JJ, Ishii I, Chun J. Lysophosphatidic acid receptors. Molecular Pharmacology. 58: 1188-96. PMID 11093753 DOI: 10.1124/Mol.58.6.1188  0.641
2001 Weiner JA, Fukushima N, Contos JJA, Scherer SS, Chun J. Regulation of Schwann Cell Morphology and Adhesion by Receptor-Mediated Lysophosphatidic Acid Signaling The Journal of Neuroscience. 21: 7069-7078. DOI: 10.1523/Jneurosci.21-18-07069.2001  0.733
2001 Contos JJ, Chun J. Corrigendum to: “The mouse lpA3/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern” [Gene 267 (2001) 243–253] Gene. 272: 345. DOI: 10.1016/S0378-1119(01)00560-1  0.342
2000 Contos JJ, Fukushima N, Weiner JA, Kaushal D, Chun J. Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proceedings of the National Academy of Sciences of the United States of America. 97: 13384-9. PMID 11087877 DOI: 10.1073/Pnas.97.24.13384  0.79
2000 Fukushima N, Weiner JA, Chun J. Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology. Developmental Biology. 228: 6-18. PMID 11087622 DOI: 10.1006/Dbio.2000.9930  0.738
2000 Hagihara K, Watanabe K, Chun J, Yamaguchi Y. Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 219: 353-67. PMID 11066092 DOI: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1059>3.0.CO;2  0.362
2000 Ishii I, Contos JJ, Fukushima N, Chun J. Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system. Molecular Pharmacology. 58: 895-902. PMID 11040035 DOI: 10.1124/Mol.58.5.895  0.736
2000 Pompeiano M, Blaschke AJ, Flavell RA, Srinivasan A, Chun J. Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system. The Journal of Comparative Neurology. 423: 1-12. PMID 10861532 DOI: 10.1002/1096-9861(20000717)423:1<1::Aid-Cne1>3.0.Co;2-S  0.7
2000 Chun J, Weiner JA, Fukushima N, Contos JJ, Zhang G, Kimura Y, Dubin A, Ishii I, Hecht JH, Akita C, Kaushal D. Neurobiology of receptor-mediated lysophospholipid signaling. From the first lysophospholipid receptor to roles in nervous system function and development. Annals of the New York Academy of Sciences. 905: 110-7. PMID 10818447 DOI: 10.1111/J.1749-6632.2000.Tb06543.X  0.81
2000 Contos JJA, Chun J. Genomic characterization of the lysophosphatidic acid receptor gene, Lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA Genomics. 64: 155-169. PMID 10729222 DOI: 10.1006/geno.2000.6122  0.341
2000 Gu Y, Sekiguchi J, Gao Y, Dikkes P, Frank K, Ferguson D, Hasty P, Chun J, Alt FW. Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 2668-73. PMID 10716994 DOI: 10.1073/Pnas.97.6.2668  0.46
1999 Chun J. Lysophospholipid receptors: Implications for neural signaling Critical Reviews in Neurobiology. 13: 151-168. PMID 10512488 DOI: 10.1615/CRITREVNEUROBIOL.V13.I2.20  0.434
1999 Chun J. Developmental neurobiology: A genetic Cheshire cat? Current Biology. 9. PMID 10508574 DOI: 10.1016/S0960-9822(99)80415-1  0.319
1999 Chun J, Contos JJ, Munroe D. A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs). Cell Biochemistry and Biophysics. 30: 213-42. PMID 10356643 DOI: 10.1007/BF02738068  0.417
1999 Marszalek JR, Weiner JA, Farlow SJ, Chun J, Goldstein LS. Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. The Journal of Cell Biology. 145: 469-79. PMID 10225949 DOI: 10.1083/jcb.145.3.469  0.56
1999 Weiner JA, Chun J. Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid. Proceedings of the National Academy of Sciences of the United States of America. 96: 5233-8. PMID 10220449 DOI: 10.1073/pnas.96.9.5233  0.642
1999 Chun J, Schatz DG. Developmental neurobiology: Alternative ends for a familiar story? Current Biology : Cb. 9: R251-3. PMID 10209111 DOI: 10.1016/S0960-9822(99)80156-0  0.578
1999 Pompeiano M, Hvala M, Chun J. Onset of apoptotic DNA fragmentation can precede cell elimination by days in the small intestinal villus. Cell Death and Differentiation. 5: 702-9. PMID 10200526 DOI: 10.1038/Sj.Cdd.4400403  0.687
1999 Chun J, Schatz DG. Rearranging views on neurogenesis: neuronal death in the absence of DNA end-joining proteins. Neuron. 22: 7-10. PMID 10027282 DOI: 10.1016/S0896-6273(00)80671-6  0.548
1999 Zhang G, Contos JJ, Weiner JA, Fukushima N, Chun J. Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. Gene. 227: 89-99. PMID 9931453 DOI: 10.1016/S0378-1119(98)00589-7  0.815
1999 Dubin AE, Bahnson T, Weiner JA, Fukushima N, Chun J. Lysophosphatidic Acid Stimulates Neurotransmitter-Like Conductance Changes that Precede GABA and l-Glutamate in Early, Presumptive Cortical Neuroblasts The Journal of Neuroscience. 19: 1371-1381. DOI: 10.1523/Jneurosci.19-04-01371.1999  0.793
1998 Contos JJA, Chun J. Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, lp(A1)/vzg-1/Gpcr26 Genomics. 51: 364-378. PMID 9721207 DOI: 10.1006/geno.1998.5400  0.36
1998 Weiner JA, Hecht JH, Chun J. Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain. The Journal of Comparative Neurology. 398: 587-98. PMID 9717712 DOI: 10.1002/(SICI)1096-9861(19980907)398:4<587::AID-CNE10>3.0.CO;2-5  0.754
1998 Blaschke AJ, Weiner JA, Chun J. Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system. The Journal of Comparative Neurology. 396: 39-50. PMID 9623886 DOI: 10.1002/(SICI)1096-9861(19980622)396:1<39::AID-CNE4>3.0.CO;2-J  0.609
1998 Fukushima N, Kimura Y, Chun J. A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid. Proceedings of the National Academy of Sciences of the United States of America. 95: 6151-6. PMID 9600933 DOI: 10.1073/Pnas.95.11.6151  0.737
1997 Staley K, Blaschke AJ, Chun J. Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends. Cell Death and Differentiation. 4: 66-75. PMID 16465212 DOI: 10.1038/Sj.Cdd.4400207  0.732
1997 Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS. D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proceedings of the National Academy of Sciences of the United States of America. 94: 11184-9. PMID 9326583 DOI: 10.1073/Pnas.94.21.11184  0.544
1997 Bain G, Engel I, Maandag ECR, Te Riele HPJ, Voland JR, Sharp LL, Chun J, Huey B, Pinkel D, Murre C. E2A deficiency leads to abnormalities in αβ T-cell development and to rapid development of T-cell lymphomas Molecular and Cellular Biology. 17: 4782-4791. PMID 9234734 DOI: 10.1128/Mcb.17.8.4782  0.313
1997 Weiner JA, Chun J. Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development. The Journal of Comparative Neurology. 381: 130-42. PMID 9130664 DOI: 10.1002/(SICI)1096-9861(19970505)381:2<130::AID-CNE2>3.0.CO;2-4  0.592
1997 Weiner JA, Chun J. Maternally derived immunoglobulin light chain is present in the fetal mammalian CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3148-56. PMID 9096149 DOI: 10.1523/Jneurosci.17-09-03148.1997  0.579
1997 Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS. Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. The Journal of Biological Chemistry. 272: 8057-64. PMID 9065479 DOI: 10.1074/Jbc.272.12.8057  0.561
1996 Hecht JH, Weiner JA, Post SR, Chun J. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. The Journal of Cell Biology. 135: 1071-83. PMID 8922387 DOI: 10.1083/Jcb.135.4.1071  0.77
1996 Chun J, Jaenisch R. Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses Molecular and Cellular Neurosciences. 7: 304-321. PMID 8793865 DOI: 10.1006/Mcne.1996.0023  0.51
1988 Chun JJ, Shatz CJ. Redistribution of synaptic vesicle antigens is correlated with the disappearance of a transient synaptic zone in the developing cerebral cortex. Neuron. 1: 297-310. PMID 3152420 DOI: 10.1016/0896-6273(88)90078-5  0.652
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