| Year |
Citation |
Score |
| 2024 |
Rajani RM, Ellingford R, Hellmuth M, Harris SS, Taso OS, Graykowski D, Lam FKW, Arber C, Fertan E, Danial JSH, Swire M, Lloyd M, Giovannucci TA, Bourdenx M, Klenerman D, ... ... Wray S, et al. Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease. Plos Biology. 22: e3002727. PMID 39042667 DOI: 10.1371/journal.pbio.3002727 |
0.351 |
|
| 2024 |
Gustavsson EK, Sethi S, Gao Y, Brenton JW, García-Ruiz S, Zhang D, Garza R, Reynolds RH, Evans JR, Chen Z, Grant-Peters M, Macpherson H, Montgomery K, Dore R, Wernick AI, ... ... Wray S, et al. The annotation of has been concealed by its protein-coding pseudogene . Science Advances. 10: eadk1296. PMID 38924406 DOI: 10.1126/sciadv.adk1296 |
0.362 |
|
| 2023 |
Arber C, Casey JM, Crawford S, Rambarack N, Yaman U, Wiethoff S, Augustin E, Piers TM, Rostagno A, Ghiso J, Lewis PA, Revesz T, Hardy J, Pocock JM, Houlden H, ... ... Wray S, et al. Microglia produce the amyloidogenic ABri peptide in familial British dementia. Biorxiv : the Preprint Server For Biology. PMID 37425748 DOI: 10.1101/2023.06.27.546552 |
0.521 |
|
| 2022 |
Willumsen N, Arber C, Lovejoy C, Toombs J, Alatza A, Weston PSJ, Chávez-Gutiérrez L, Hardy J, Zetterberg H, Fox NC, Ryan NS, Lashley T, Wray S. The PSEN1 E280G mutation leads to increased amyloid-β43 production in induced pluripotent stem cell neurons and deposition in brain tissue. Brain Communications. 5: fcac321. PMID 36687397 DOI: 10.1093/braincomms/fcac321 |
0.43 |
|
| 2022 |
Wei J, Arber C, Wray S, Hardy J, Piers TM, Pocock JM. Human myeloid progenitor glucocorticoid receptor activation causes genomic instability, type 1 IFN- response pathway activation and senescence in differentiated microglia; an early life stress model. Glia. PMID 36571248 DOI: 10.1002/glia.24325 |
0.307 |
|
| 2022 |
Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, ... ... Wray S, et al. A reference human induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell. 29: 1685-1702.e22. PMID 36459969 DOI: 10.1016/j.stem.2022.11.004 |
0.435 |
|
| 2022 |
Gabriele RMC, Abel E, Fox NC, Wray S, Arber C. Knockdown of Amyloid Precursor Protein: Biological Consequences and Clinical Opportunities. Frontiers in Neuroscience. 16: 835645. PMID 35360155 DOI: 10.3389/fnins.2022.835645 |
0.304 |
|
| 2022 |
Gomez-Suaga P, Mórotz GM, Markovinovic A, Martín-Guerrero SM, Preza E, Arias N, Mayl K, Aabdien A, Gesheva V, Nishimura A, Annibali A, Lee Y, Mitchell JC, Wray S, Shaw C, et al. Disruption of ER-mitochondria tethering and signalling in C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia. Aging Cell. e13549. PMID 35026048 DOI: 10.1111/acel.13549 |
0.552 |
|
| 2021 |
Lines G, Arber C, Preza E, Leckey CA, Myeku N, Casey JM, Perkinton M, Wray S. Investigating changes in the proteostasis capabilities of iPSC-neurons during development and in FTD using iPSC-neurons with MAPT mutations. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058308. PMID 34971145 DOI: 10.1002/alz.058308 |
0.34 |
|
| 2021 |
Mallach A, Gobom J, Arber C, Piers TM, Hardy J, Wray S, Zetterberg H, Pocock J. Differential Stimulation of Pluripotent Stem Cell-Derived Human Microglia Leads to Exosomal Proteomic Changes Affecting Neurons. Cells. 10. PMID 34831089 DOI: 10.3390/cells10112866 |
0.426 |
|
| 2021 |
Mallach A, Gobom J, Zetterberg H, Hardy J, Piers TM, Wray S, Pocock JM. The influence of the R47H triggering receptor expressed on myeloid cells 2 variant on microglial exosome profiles. Brain Communications. 3: fcab009. PMID 34704019 DOI: 10.1093/braincomms/fcab009 |
0.386 |
|
| 2021 |
Kopach O, Esteras N, Wray S, Abramov AY, Rusakov DA. Genetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia. Cell Death & Disease. 12: 716. PMID 34274950 DOI: 10.1038/s41419-021-04007-w |
0.335 |
|
| 2021 |
Esteras N, Kopach O, Maiolino M, Lariccia V, Amoroso S, Qamar S, Wray S, Rusakov DA, Jaganjac M, Abramov AY. Mitochondrial ROS control neuronal excitability and cell fate in frontotemporal dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34057756 DOI: 10.1002/alz.12394 |
0.359 |
|
| 2021 |
Simone R, Javad F, Emmett W, Wilkins OG, Almeida FL, Barahona-Torres N, Zareba-Paslawska J, Ehteramyan M, Zuccotti P, Modelska A, Siva K, Virdi GS, Mitchell JS, Harley J, Kay VA, ... ... Wray S, et al. MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature. PMID 34012113 DOI: 10.1038/s41586-021-03556-6 |
0.377 |
|
| 2021 |
Arber C, Alatza A, Leckey CA, Paterson RW, Zetterberg H, Wray S. Mass spectrometry analysis of tau and amyloid-beta in iPSC-derived models of Alzheimer's disease and dementia. Journal of Neurochemistry. PMID 33539581 DOI: 10.1111/jnc.15315 |
0.372 |
|
| 2021 |
Arber C, Lovejoy C, Harris L, Willumsen N, Alatza A, Casey JM, Lines G, Kerins C, Mueller AK, Zetterberg H, Hardy J, Ryan NS, Fox NC, Lashley T, Wray S. Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis. Cell Reports. 34: 108615. PMID 33440141 DOI: 10.1016/j.celrep.2020.108615 |
0.438 |
|
| 2020 |
Lines G, Casey JM, Preza E, Wray S. Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells. Molecular and Cellular Neurosciences. 109: 103553. PMID 32956830 DOI: 10.1016/J.Mcn.2020.103553 |
0.432 |
|
| 2020 |
Kopach O, Esteras N, Wray S, Rusakov DA, Abramov AY. Maturation and phenotype of pathophysiological neuronal excitability of human cells in tau-related dementia. Journal of Cell Science. PMID 32299835 DOI: 10.1242/Jcs.241687 |
0.453 |
|
| 2020 |
Satir TM, Nazir FH, Vizlin-Hodzic D, Hardselius E, Blennow K, Wray S, Zetterberg H, Agholme L, Bergström P. Author Correction: Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons. Scientific Reports. 10: 3993. PMID 32111958 DOI: 10.1038/S41598-020-61008-Z |
0.362 |
|
| 2020 |
Satir TM, Nazir FH, Vizlin-Hodzic D, Hardselius E, Blennow K, Wray S, Zetterberg H, Agholme L, Bergström P. Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons. Scientific Reports. 10: 601. PMID 31953468 DOI: 10.1038/S41598-020-57516-7 |
0.416 |
|
| 2020 |
Ling H, Gelpi E, Davey K, Jaunmuktane Z, Mok KY, Jabbari E, Simone R, R'Bibo L, Brandner S, Ellis MJ, Attems J, Mann D, Halliday GM, Al-Sarraj S, Hedreen J, ... ... Wray S, et al. Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates. Acta Neuropathologica. PMID 31950334 DOI: 10.1007/S00401-019-02119-4 |
0.488 |
|
| 2019 |
Arber C, Villegas-Llerena C, Toombs J, Pocock JM, Ryan NS, Fox NC, Zetterberg H, Hardy J, Wray S. Amyloid precursor protein processing in human neurons with an allelic series of the intron 4 deletion mutation and total presenilin-1 knockout. Brain Communications. 1: fcz024. PMID 32395715 DOI: 10.1093/braincomms/fcz024 |
0.456 |
|
| 2019 |
Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, ... Wray S, et al. SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases. Nature Reviews. Neurology. PMID 31222062 DOI: 10.1038/S41582-019-0222-0 |
0.411 |
|
| 2019 |
Soutar MPM, Kempthorne L, Annuario E, Luft C, Wray S, Ketteler R, Ludtmann MHR, Plun-Favreau H. FBS/BSA media concentration determines CCCP's ability to depolarize mitochondria and activate PINK1-PRKN mitophagy. Autophagy. 1-10. PMID 31060423 DOI: 10.1080/15548627.2019.1603549 |
0.306 |
|
| 2019 |
Arber C, Toombs J, Lovejoy CC, Ryan NS, Paterson RW, Willumsen N, Gkanatsiou E, Portelius E, Blennow K, Heslegrave A, Schott JM, Hardy J, Lashley T, Fox NC, Zetterberg H, ... Wray S, et al. Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta. Molecular Psychiatry. PMID 30980041 DOI: 10.1038/S41380-019-0410-8 |
0.555 |
|
| 2019 |
Paonessa F, Evans LD, Solanki R, Larrieu D, Wray S, Hardy J, Jackson SP, Livesey FJ. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. Cell Reports. 26: 582-593.e5. PMID 30650353 DOI: 10.1016/J.Celrep.2018.12.085 |
0.545 |
|
| 2019 |
Leckey CA, Hällqvist J, Doykov ID, Mills K, Wray S, Fox NC, Zetterberg H, Paterson RW. P1-261: DEVELOPMENT OF A UNIFIED -OMIC PREPARATION METHODOLOGY: AN ALTERNATIVE, NON-IP APPROACH TO TARGETED LC-MS/MS DETECTION OF SECRETED AMYLOID-β PEPTIDES IN CEREBROSPINAL FLUID AND IPSC-DERIVED FAMILIAL ALZHEIMER'S DISEASE MODELS Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.816 |
0.313 |
|
| 2019 |
Arber C, Toombs J, Lovejoy CE, Paterson RW, Ryan NS, Willumsen N, Gkanatsiou E, Portelius E, Blennow K, Heslegrave AJ, Schott JM, Hardy J, Fox NC, Lashley T, Zetterberg H, ... Wray S, et al. CORTICAL NEURONS AND CEREBRAL ORGANOIDS FROM APP AND PSEN1 MUTATION CARRIERS REVEAL MUTATION-SPECIFIC EFFECTS ON Aβ PRODUCTION Alzheimer's & Dementia. 15: P199. DOI: 10.1016/J.Jalz.2019.06.4532 |
0.476 |
|
| 2019 |
Esteve AS, Leckey CA, Arber C, Toombs J, Wray S, Heslegrave AJ, Strooper BD, Zetterberg H. P2-244: Neurofilament Light In Isopotential Stem Cell-Derived Neurons With Familial Ad Mutations As A Marker Of Neurodegeneration Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2651 |
0.396 |
|
| 2018 |
Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, et al. Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes. Stem Cell Reports. PMID 30057263 DOI: 10.1016/J.Stemcr.2018.06.022 |
0.457 |
|
| 2018 |
Mamais A, Manzoni C, Nazish I, Arber C, Sonustun B, Wray S, Warner TT, Cookson MR, Lewis PA, Bandopadhyay R. Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology. Brain Research. PMID 30055128 DOI: 10.1016/J.Brainres.2018.07.023 |
0.509 |
|
| 2018 |
Soutar MPM, Kempthorne L, Miyakawa S, Annuario E, Melandri D, Harley J, O'Sullivan GA, Wray S, Hancock DC, Cookson MR, Downward J, Carlton M, Plun-Favreau H. AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons. Scientific Reports. 8: 8855. PMID 29891871 DOI: 10.1038/S41598-018-26949-6 |
0.535 |
|
| 2018 |
Giacomini C, Koo CY, Yankova N, Tavares IA, Wray S, Noble W, Hanger DP, Morris JDH. A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies. Acta Neuropathologica Communications. 6: 37. PMID 29730992 DOI: 10.1186/S40478-018-0539-8 |
0.73 |
|
| 2018 |
Lorenzi M, Altmann A, Gutman B, Wray S, Arber C, Hibar DP, Jahanshad N, Schott JM, Alexander DC, Thompson PM, Ourselin S. Susceptibility of brain atrophy toin Alzheimer's disease, evidence from functional prioritization in imaging genetics. Proceedings of the National Academy of Sciences of the United States of America. PMID 29511103 DOI: 10.1073/Pnas.1706100115 |
0.381 |
|
| 2018 |
Ritchie L, Tate R, Chamberlain LH, Robertson G, Zagnoni M, Sposito T, Wray S, Wright JA, Bryant CE, Gay NJ, Bushell TJ. Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons. Neuropharmacology. PMID 29505789 DOI: 10.1016/J.Neuropharm.2018.02.025 |
0.321 |
|
| 2017 |
Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, ... ... Wray S, et al. G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. Embo Molecular Medicine. PMID 29113975 DOI: 10.15252/Emmm.201707850 |
0.304 |
|
| 2017 |
Arber C, Angelova PR, Wiethoff S, Tsuchiya Y, Mazzacuva F, Preza E, Bhatia KP, Mills K, Gout I, Abramov AY, Hardy J, Duce JA, Houlden H, Wray S. iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease. Plos One. 12: e0184104. PMID 28863176 DOI: 10.1371/Journal.Pone.0184104 |
0.485 |
|
| 2017 |
Haenseler W, Zambon F, Lee H, Vowles J, Rinaldi F, Duggal G, Houlden H, Gwinn K, Wray S, Luk KC, Wade-Martins R, James WS, Cowley SA. Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages. Scientific Reports. 7: 9003. PMID 28827786 DOI: 10.1038/S41598-017-09362-3 |
0.407 |
|
| 2017 |
Arber C, Lovejoy C, Wray S. Stem cell models of Alzheimer's disease: progress and challenges. Alzheimer's Research & Therapy. 9: 42. PMID 28610595 DOI: 10.1186/S13195-017-0268-4 |
0.442 |
|
| 2017 |
Wray S. Modeling tau pathology in human stem cell derived neurons. Brain Pathology (Zurich, Switzerland). 27: 525-529. PMID 28585382 DOI: 10.1111/bpa.12521 |
0.421 |
|
| 2017 |
Hall CE, Yao Z, Choi M, Tyzack GE, Serio A, Luisier R, Harley J, Preza E, Arber C, Crisp SJ, Watson PMD, Kullmann DM, Abramov AY, Wray S, Burley R, et al. Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Reports. 19: 1739-1749. PMID 28564594 DOI: 10.1016/J.Celrep.2017.05.024 |
0.342 |
|
| 2017 |
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, ... ... Wray S, et al. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28539470 DOI: 10.1126/Scitranslmed.Aaf3962 |
0.339 |
|
| 2017 |
Ludtmann MH, Arber C, Bartolome F, de Vicente M, Preza E, Carro E, Houlden H, Gandhi S, Wray S, Abramov AY. Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons. The Journal of Biological Chemistry. PMID 28360103 DOI: 10.1074/Jbc.M116.762898 |
0.368 |
|
| 2017 |
Esteras N, Rohrer JD, Hardy J, Wray S, Abramov AY. Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration. Redox Biology. 12: 410-422. PMID 28319892 DOI: 10.1016/J.Redox.2017.03.008 |
0.514 |
|
| 2017 |
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, Radaelli E, Tesseur I, Wray S, Ebneth A, et al. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Neuron. PMID 28238547 DOI: 10.1016/J.Neuron.2017.02.001 |
0.574 |
|
| 2017 |
Toombs J, Foiani MS, Paterson RW, Heslegrave A, Wray S, Schott JM, Fox NC, Lunn MP, Blennow K, Zetterberg H. Effect of Spinal Manometers on Cerebrospinal Fluid Amyloid-β Concentration. Journal of Alzheimer's Disease : Jad. PMID 28059797 DOI: 10.3233/Jad-161126 |
0.313 |
|
| 2017 |
Toombs J, Arber C, Ryan NS, Heslegrave AJ, Hardy J, Strooper BD, Fox NC, Wray S, Zetterberg H. DISTINCT Aβ PRODUCTION IN STEM CELL-DERIVED CORTICAL NEURONS FROM PATIENTS WITH FAD MUTATION Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.247 |
0.499 |
|
| 2017 |
Arber C, James Lovejoy CE, Ryan NS, Toombs J, Willumsen N, Fox NC, Hardy J, Wray S. PROBING DEVELOPMENTAL CONSEQUENCES OF PSEN1 MUTATIONS IN IPSC DIFFERENTIATION IN 2D AND 3D Alzheimer's & Dementia. 13: P242. DOI: 10.1016/J.Jalz.2017.06.092 |
0.381 |
|
| 2017 |
James Lovejoy CE, Arber C, Willumsen N, Ryan NS, Lashley T, Fox NC, Hardy J, Wray S. [P1-220]: 3D CEREBRAL ORGANOIDS AS IN VITRO MODELS FOR ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P327-P327. DOI: 10.1016/J.Jalz.2017.06.040 |
0.469 |
|
| 2016 |
Bergström P, Agholme L, Nazir FH, Satir TM, Toombs J, Wellington H, Strandberg J, Bontell TO, Kvartsberg H, Holmström M, Boreström C, Simonsson S, Kunath T, Lindahl A, Blennow K, ... ... Wray S, et al. Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation. Scientific Reports. 6: 29200. PMID 27383650 DOI: 10.1038/Srep29200 |
0.413 |
|
| 2016 |
Wu JW, Hussaini SA, Bastille IM, Rodriguez GA, Mrejeru A, Rilett K, Sanders DW, Cook C, Fu H, Boonen RA, Herman M, Nahmani E, Emrani S, Figueroa YH, Diamond MI, ... ... Wray S, et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nature Neuroscience. PMID 27322420 DOI: 10.1038/Nn.4328 |
0.629 |
|
| 2016 |
Preza E, Hardy J, Warner T, Wray S. Induced pluripotent stem cell models of frontotemporal dementia. Neuropathology and Applied Neurobiology. PMID 27291591 DOI: 10.1111/Nan.12334 |
0.498 |
|
| 2016 |
Šimić G, Leko MB, Wray S, Harrington C, Delalle I, Jovanov-Milošević N, Bažadona D, Buée L, Silva R, Giovanni GD, Wischik C, Hof PR. Monoaminergic Neuropathology in Alzheimer's disease. Progress in Neurobiology. PMID 27084356 DOI: 10.1016/J.Pneurobio.2016.04.001 |
0.404 |
|
| 2016 |
Šimić G, Babić Leko M, Wray S, Harrington C, Delalle I, Jovanov-Milošević N, Bažadona D, Buée L, de Silva R, Di Giovanni G, Wischik C, Hof PR. Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies. Biomolecules. 6. PMID 26751493 DOI: 10.3390/biom6010006 |
0.363 |
|
| 2015 |
Wray S, Fox NC. Stem cell therapy for Alzheimer's disease: hope or hype? The Lancet. Neurology. PMID 26704440 DOI: 10.1016/S1474-4422(15)00382-8 |
0.35 |
|
| 2015 |
Sposito T, Preza E, Mahoney CJ, Setó-Salvia N, Ryan NS, Morris HR, Arber C, Devine MJ, Houlden H, Warner TT, Bushell TJ, Zagnoni M, Kunath T, Livesey FJ, Fox NC, ... ... Wray S, et al. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT. Human Molecular Genetics. PMID 26136155 DOI: 10.1093/Hmg/Ddv246 |
0.583 |
|
| 2015 |
Wiethoff S, Arber C, Li A, Wray S, Houlden H, Patani R. Using human induced pluripotent stem cells (hiPSC) to model cerebellar disease: Hope and hype. Journal of Neurogenetics. 1-25. PMID 25985846 DOI: 10.3109/01677063.2015.1053478 |
0.369 |
|
| 2015 |
Arber CE, Li A, Houlden H, Wray S. Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories. Neuropathology and Applied Neurobiology. PMID 25870938 DOI: 10.1111/Nan.12242 |
0.334 |
|
| 2015 |
Rohrer JD, Isaacs AM, Mizielinska S, Mead S, Lashley T, Wray S, Sidle K, Fratta P, Orrell RW, Hardy J, Holton J, Revesz T, Rossor MN, Warren JD. C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis. The Lancet. Neurology. 14: 291-301. PMID 25638642 DOI: 10.1016/S1474-4422(14)70233-9 |
0.463 |
|
| 2015 |
Fratta P, Polke JM, Newcombe J, Mizielinska S, Lashley T, Poulter M, Beck J, Preza E, Devoy A, Sidle K, Howard R, Malaspina A, Orrell RW, Clarke J, Lu CH, ... ... Wray S, et al. Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion. Neurobiology of Aging. 36: 546.e1-7. PMID 25179228 DOI: 10.1016/J.Neurobiolaging.2014.07.037 |
0.331 |
|
| 2015 |
Esteras Gallego N, Wray S, Preza E, Abramov AY. Higher Mitochondrial Membrane Potential Induces ROS Production in the Familiar Form of Frontotemporal Dementia with MAPT Mutations Biophysical Journal. 108: 611a. DOI: 10.1016/J.Bpj.2014.11.3324 |
0.363 |
|
| 2014 |
Atherton J, Kurbatskaya K, Bondulich M, Croft CL, Garwood CJ, Chhabra R, Wray S, Jeromin A, Hanger DP, Noble W. Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease. Aging Cell. 13: 49-59. PMID 23919677 DOI: 10.1111/Acel.12148 |
0.716 |
|
| 2013 |
Burchell VS, Nelson DE, Sanchez-Martinez A, Delgado-Camprubi M, Ivatt RM, Pogson JH, Randle SJ, Wray S, Lewis PA, Houlden H, Abramov AY, Hardy J, Wood NW, Whitworth AJ, Laman H, et al. The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nature Neuroscience. 16: 1257-65. PMID 23933751 DOI: 10.1038/Nn.3489 |
0.482 |
|
| 2013 |
Bartolome F, Wu HC, Burchell VS, Preza E, Wray S, Mahoney CJ, Fox NC, Calvo A, Canosa A, Moglia C, Mandrioli J, Chiò A, Orrell RW, Houlden H, Hardy J, et al. Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels. Neuron. 78: 57-64. PMID 23498975 DOI: 10.1016/J.Neuron.2013.02.028 |
0.447 |
|
| 2013 |
Wray S, Preza E, Rollinson S, Ryten M, Isaacs A, Houlden H, Rossor M, Chio A, Morris H, Pickering-Brown S, Hardy J, Livesey R, Kunath T. O1-01-06: Human stem cell models of frontotemporal dementia caused by a non-coding hexanucleotide repeat expansion in C9ORF72 Alzheimer's & Dementia. 9: P127-P127. DOI: 10.1016/J.Jalz.2013.04.054 |
0.424 |
|
| 2012 |
Wray S, Self M, Lewis PA, Taanman JW, Ryan NS, Mahoney CJ, Liang Y, Devine MJ, Sheerin UM, Houlden H, Morris HR, Healy D, et al. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. Plos One. 7: e43099. PMID 22952635 DOI: 10.1371/Journal.Pone.0043099 |
0.476 |
|
| 2012 |
Fawcett KA, Murphy SM, Polke JM, Wray S, Burchell VS, Manji H, Quinlivan RM, Zdebik AA, Reilly MM, Houlden H. Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 1204-9. PMID 22851605 DOI: 10.1136/Jnnp-2012-303055 |
0.301 |
|
| 2012 |
Trabzuni D, Wray S, Vandrovcova J, Ramasamy A, Walker R, Smith C, Luk C, Gibbs JR, Dillman A, Hernandez DG, Arepalli S, Singleton AB, Cookson MR, Pittman AM, de Silva R, et al. MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies. Human Molecular Genetics. 21: 4094-103. PMID 22723018 DOI: 10.1093/Hmg/Dds238 |
0.65 |
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| 2012 |
Crehan H, Holton P, Wray S, Pocock J, Guerreiro R, Hardy J. Complement receptor 1 (CR1) and Alzheimer's disease. Immunobiology. 217: 244-50. PMID 21840620 DOI: 10.1016/J.Imbio.2011.07.017 |
0.63 |
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| 2011 |
Ahmed Z, Doherty KM, Silveira-Moriyama L, Bandopadhyay R, Lashley T, Mamais A, Hondhamuni G, Wray S, Newcombe J, O'Sullivan SS, Wroe S, de Silva R, Holton JL, Lees AJ, Revesz T. Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies. Acta Neuropathologica. 122: 415-28. PMID 21773886 DOI: 10.1007/S00401-011-0857-4 |
0.386 |
|
| 2011 |
Hardy J, Guerreiro R, Wray S, Ferrari R, Momeni P. The genetics of Alzheimer's disease and other tauopathies Journal of Alzheimer's Disease. 23: S33-S39. DOI: 10.3233/Jad-2011-001433 |
0.534 |
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| 2010 |
Wray S, Lewis PA. A tangled web - tau and sporadic Parkinson's disease. Frontiers in Psychiatry. 1: 150. PMID 21423457 DOI: 10.3389/Fpsyt.2010.00150 |
0.342 |
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| 2010 |
Hanger DP, Wray S. Tau cleavage and tau aggregation in neurodegenerative disease. Biochemical Society Transactions. 38: 1016-20. PMID 20658996 DOI: 10.1042/Bst0381016 |
0.664 |
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| 2010 |
Wray S, Devine M, Kunath T, Duff K, Morris HR, Houlden H, Rossor MN, Hardy J, Lewis PA. P1-111: Progress towards a neuronal cell model of the tauopathies Alzheimer's & Dementia. 6: S206-S207. DOI: 10.1016/J.Jalz.2010.05.660 |
0.589 |
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| 2009 |
Wray S, Noble W. Linking amyloid and tau pathology in Alzheimer's disease: the role of membrane cholesterol in Abeta-mediated tau toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9665-7. PMID 19657019 DOI: 10.1523/Jneurosci.2234-09.2009 |
0.618 |
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| 2008 |
Reynolds CH, Garwood CJ, Wray S, Price C, Kellie S, Perera T, Zvelebil M, Yang A, Sheppard PW, Varndell IM, Hanger DP, Anderton BH. Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases. The Journal of Biological Chemistry. 283: 18177-86. PMID 18467332 DOI: 10.1074/Jbc.M709715200 |
0.631 |
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| 2008 |
Wray S, Saxton M, Anderton BH, Hanger DP. Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats. Journal of Neurochemistry. 105: 2343-52. PMID 18315566 DOI: 10.1111/J.1471-4159.2008.05321.X |
0.649 |
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| 2008 |
Wray S, Anderton BH, Hanger DP. P2-132: Potential toxicity of tau cleavage products in progressive supranuclear palsy Alzheimer's & Dementia. 4: T409-T409. DOI: 10.1016/J.Jalz.2008.05.1205 |
0.595 |
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| 2007 |
Hanger DP, Byers HL, Wray S, Leung KY, Saxton MJ, Seereeram A, Reynolds CH, Ward MA, Anderton BH. Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. The Journal of Biological Chemistry. 282: 23645-54. PMID 17562708 DOI: 10.1074/Jbc.M703269200 |
0.616 |
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| 2006 |
Toombs J, Arber C, James Lovejoy CE, Paterson RW, Ryan NS, Willumsen N, Gkanatsiou E, Portelius E, Blennow K, Heslegrave A, Schott JM, Hardy J, Lashley T, Fox NC, Zetterberg H, ... Wray S, et al. P1-188: MODELLING AMYLOID BETA PROFILES IN IPSC-DERIVED CORTICAL NEURONS OF MULTIPLE FAMILIAL ALZHEIMER'S DISEASE GENOTYPES, INCLUDING A CASE STUDY OF SAME DONOR CULTURE MEDIA, CSF AND BRAIN TISSUE Alzheimer's & Dementia. 14: P350-P351. DOI: 10.1016/J.Jalz.2018.06.192 |
0.518 |
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| 2006 |
Wray S, Revesz T, Holton JL, Anderton BH, Hanger DP. P3-309: Enrichment of insoluble tau from progressive supranuclear palsy brain tissue Alzheimer's & Dementia. 2: S466-S466. DOI: 10.1016/J.Jalz.2006.05.1579 |
0.6 |
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