| Year |
Citation |
Score |
| 2023 |
Ramirez S, Koerich S, Astudillo N, De Gregorio N, Al-Lahham R, Allison T, Rocha NP, Wang F, Soto C. Plasma Exchange Reduces Aβ Levels in Plasma and Decreases Amyloid Plaques in the Brain in a Mouse Model of Alzheimer's Disease. International Journal of Molecular Sciences. 24. PMID 38069410 DOI: 10.3390/ijms242317087 |
0.306 |
|
| 2023 |
Banerjee V, Wang F, Sarnataro D, Soto C. Editorial: Prion-Like transmission of pathogenic proteins in neurodegenerative diseases: structural and molecular bases. Frontiers in Molecular Biosciences. 10: 1294465. PMID 37808521 DOI: 10.3389/fmolb.2023.1294465 |
0.338 |
|
| 2023 |
Concha-Marambio L, Wang F, Armijo E, Gorski D, Ramirez F, Scowcroft A, Pritzkow S, Soto C. Development of a methodology for large-scale production of prions for biological and structural studies. Frontiers in Molecular Biosciences. 10: 1184029. PMID 37635939 DOI: 10.3389/fmolb.2023.1184029 |
0.331 |
|
| 2023 |
Becerra-Calixto A, Mukherjee A, Ramirez S, Sepulveda S, Sinha T, Al-Lahham R, De Gregorio N, Gherardelli C, Soto C. Lewy Body-like Pathology and Loss of Dopaminergic Neurons in Midbrain Organoids Derived from Familial Parkinson's Disease Patient. Cells. 12. PMID 36831291 DOI: 10.3390/cells12040625 |
0.525 |
|
| 2023 |
Cuanalo-Contreras K, Schulz J, Mukherjee A, Park KW, Armijo E, Soto C. Extensive accumulation of misfolded protein aggregates during natural aging and senescence. Frontiers in Aging Neuroscience. 14: 1090109. PMID 36778589 DOI: 10.3389/fnagi.2022.1090109 |
0.61 |
|
| 2022 |
Mukherjee A, Cuanalo-Contreras K, Sood A, Soto C. Development of a novel pharmacophore model to screen specific inhibitors for the serine-threonine protein phosphatase calcineurin. Biochemistry and Biophysics Reports. 31: 101311. PMID 36032402 DOI: 10.1016/j.bbrep.2022.101311 |
0.516 |
|
| 2022 |
Urayama A, Moreno-Gonzalez I, Morales-Scheihing D, Kharat V, Pritzkow S, Soto C. Preventive and therapeutic reduction of amyloid deposition and behavioral impairments in a model of Alzheimer's disease by whole blood exchange. Molecular Psychiatry. PMID 35835859 DOI: 10.1038/s41380-022-01679-4 |
0.33 |
|
| 2022 |
Mukherjee A, Al-Lahham R, Corkins ME, Samanta S, Schmeichel AM, Singer W, Low PA, Govindaraju T, Soto C. Identification of Multicolor Fluorescent Probes for Heterogeneous Aβ Deposits in Alzheimer's Disease. Frontiers in Aging Neuroscience. 13: 802614. PMID 35185519 DOI: 10.3389/fnagi.2021.802614 |
0.569 |
|
| 2022 |
Moreno-Gonzalez I, Edwards G, Morales R, Duran-Aniotz C, Escobedo G, Marquez M, Pumarola M, Soto C. Aged Cattle Brain Displays Alzheimer's Disease-Like Pathology and Promotes Brain Amyloidosis in a Transgenic Animal Model. Frontiers in Aging Neuroscience. 13: 815361. PMID 35173603 DOI: 10.3389/fnagi.2021.815361 |
0.361 |
|
| 2021 |
Ramirez S, Mukherjee A, Sepulveda SE, Gherardelli C, Becerra-Calixto A, Bravo-Vasquez N, Soto C. Protocol for controlled cortical impact in human cerebral organoids to model traumatic brain injury. Star Protocols. 2: 100987. PMID 34927096 DOI: 10.1016/j.xpro.2021.100987 |
0.498 |
|
| 2021 |
Ramirez S, Mukherjee A, Sepulveda S, Becerra-Calixto A, Bravo-Vasquez N, Gherardelli C, Chavez M, Soto C. Modeling Traumatic Brain Injury in Human Cerebral Organoids. Cells. 10. PMID 34685663 DOI: 10.3390/cells10102683 |
0.531 |
|
| 2021 |
Diao X, Wang F, Becerra-Calixto A, Soto C, Mukherjee A. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology. Cells. 10. PMID 34572052 DOI: 10.3390/cells10092402 |
0.52 |
|
| 2021 |
Morales R, Bravo-Alegria J, Moreno-Gonzalez I, Duran-Aniotz C, Gamez N, Edwards Iii G, Soto C. Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates. Molecular Psychiatry. PMID 34002023 DOI: 10.1038/s41380-021-01150-w |
0.302 |
|
| 2021 |
Duran-Aniotz C, Moreno-Gonzalez I, Gamez N, Perez-Urrutia N, Vegas-Gomez L, Soto C, Morales R. Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability. Acta Neuropathologica Communications. 9: 56. PMID 33785065 DOI: 10.1186/s40478-021-01155-0 |
0.326 |
|
| 2021 |
Mukherjee A, Becerra Calixto AD, Chavez M, Delgado JP, Soto C. Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases? Progress in Molecular Biology and Translational Science. 177: 49-63. PMID 33453942 DOI: 10.1016/bs.pmbts.2020.10.001 |
0.583 |
|
| 2020 |
Morales R, Duran-Aniotz C, Bravo-Alegria J, Estrada LD, Shahnawaz M, Hu PP, Kramm C, Morales-Scheihing D, Urayama A, Soto C. Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease. Acta Neuropathologica Communications. 8: 213. PMID 33287898 DOI: 10.1186/s40478-020-01087-1 |
0.336 |
|
| 2020 |
Tetz G, Pinho M, Pritzkow S, Mendez N, Soto C, Tetz V. Bacterial DNA promotes Tau aggregation. Scientific Reports. 10: 2369. PMID 32047247 DOI: 10.1038/S41598-020-59364-X |
0.401 |
|
| 2020 |
Shahnawaz M, Mukherjee A, Pritzkow S, Mendez N, Rabadia P, Liu X, Hu B, Schmeichel A, Singer W, Wu G, Tsai AL, Shirani H, Nilsson KPR, Low PA, Soto C. Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy. Nature. PMID 32025029 DOI: 10.1038/S41586-020-1984-7 |
0.625 |
|
| 2020 |
Concha-Marambio L, Chacon MA, Soto C. Preclinical Detection of Prions in Blood of Nonhuman Primates Infected with Variant Creutzfeldt-Jakob Disease. Emerging Infectious Diseases. 26: 34-43. PMID 31855141 DOI: 10.3201/Eid2601.181423 |
0.344 |
|
| 2019 |
Kramm C, Gomez-Gutierrez R, Soto C, Telling G, Nichols T, Morales R. In Vitro detection of Chronic Wasting Disease (CWD) prions in semen and reproductive tissues of white tailed deer bucks (Odocoileus virginianus). Plos One. 14: e0226560. PMID 31887141 DOI: 10.1371/Journal.Pone.0226560 |
0.329 |
|
| 2019 |
Escobar LE, Pritzkow S, Winter SN, Grear DA, Kirchgessner MS, Dominguez-Villegas E, Machado G, Townsend Peterson A, Soto C. The ecology of chronic wasting disease in wildlife. Biological Reviews of the Cambridge Philosophical Society. PMID 31750623 DOI: 10.1111/Brv.12568 |
0.364 |
|
| 2019 |
Edwards Iii G, Gamez N, Armijo E, Kramm C, Morales R, Taylor-Presse K, Schulz PE, Soto C, Moreno-Gonzalez I. Peripheral Delivery of Neural Precursor Cells Ameliorates Parkinson's Disease-Associated Pathology. Cells. 8. PMID 31671704 DOI: 10.3390/Cells8111359 |
0.318 |
|
| 2019 |
Oñate M, Catenaccio A, Salvadores N, Saquel C, Martinez A, Moreno-Gonzalez I, Gamez N, Soto P, Soto C, Hetz C, Court FA. The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease. Cell Death and Differentiation. PMID 31591470 DOI: 10.1038/S41418-019-0408-4 |
0.326 |
|
| 2019 |
Mays CE, Armijo E, Morales R, Kramm C, Flores A, Tiwari A, Bian J, Telling GC, Pandita TK, Hunt CR, Soto C. Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70). The Journal of Biological Chemistry. PMID 31320473 DOI: 10.1074/Jbc.Ra118.006186 |
0.418 |
|
| 2019 |
Edwards Iii GA, Zhao J, Dash PK, Soto C, Moreno-Gonzalez I. Traumatic brain injury induces tau aggregation and spreading. Journal of Neurotrauma. PMID 31317824 DOI: 10.1089/neu.2018.6348 |
0.387 |
|
| 2019 |
Kwon S, Moreno-Gonzalez I, Taylor-Presse K, Edwards Iii G, Gamez N, Calderon O, Zhu B, Velasquez FC, Soto C, Sevick-Muraca EM. Impaired Peripheral Lymphatic Function and Cerebrospinal Fluid Outflow in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31104026 DOI: 10.3233/Jad-190013 |
0.321 |
|
| 2019 |
Cali I, Lavrich J, Moda F, Kofskey D, Nemani SK, Appleby B, Tagliavini F, Soto C, Gambetti P, Notari S. PMCA-replicated PrP in urine of vCJD patients maintains infectivity and strain characteristics of brain PrP: Transmission study. Scientific Reports. 9: 5191. PMID 30914754 DOI: 10.1038/S41598-019-41694-0 |
0.449 |
|
| 2019 |
Lyon A, Mays CE, Borriello F, Telling GC, Soto C, Pritzkow S. Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics. Scientific Reports. 9: 4847. PMID 30890734 DOI: 10.1038/S41598-019-41055-X |
0.341 |
|
| 2019 |
Kang UJ, Boehme AK, Fairfoul G, Shahnawaz M, Ma TC, Hutten SJ, Green A, Soto C. Comparative study of cerebrospinal fluid α-synuclein seeding aggregation assays for diagnosis of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30840785 DOI: 10.1002/Mds.27646 |
0.377 |
|
| 2019 |
Concha-Marambio L, Shahnawaz M, Soto C. Detection of Misfolded α-Synuclein Aggregates in Cerebrospinal Fluid by the Protein Misfolding Cyclic Amplification Platform. Methods in Molecular Biology (Clifton, N.J.). 1948: 35-44. PMID 30771168 DOI: 10.1007/978-1-4939-9124-2_4 |
0.365 |
|
| 2019 |
Morales R, Gomez-Gutierrez R, Kramm C, Tycko R, Soto C. INDUCTION OF DIFFERENT BRAIN PATHOLOGY IN MICE TREATED WITH TWO MISFOLDED Aβ CONFORMERS Alzheimer's & Dementia. 15: P199-P200. DOI: 10.1016/J.Jalz.2019.06.4533 |
0.358 |
|
| 2019 |
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Jiang S, Kramár E, Nuñez-Diaz C, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Soto C, Gutierrez A, Moreno-Gonzalez I, et al. P3-069: HUMAN WILD TYPE Aβ KNOCK-IN MICE AS A BASIS TO STUDY SPORADIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P953-P953. DOI: 10.1016/J.Jalz.2019.06.3096 |
0.373 |
|
| 2019 |
Ruiz NG, Edwards GA, Kramm-Barria C, Fuentes EAA, Morales R, Soto C, Moreno-Gonzalez I. P3-050: Peripheral Inoculation Of Neural Precursors Improves Parkinson'S Disease Pathology Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3076 |
0.345 |
|
| 2018 |
Liu C, Chyr J, Zhao W, Xu Y, Ji Z, Tan H, Soto C, Zhou X. Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development. Frontiers in Genetics. 9: 410. PMID 30319691 DOI: 10.3389/Fgene.2018.00410 |
0.317 |
|
| 2018 |
Soto C, Pritzkow S. Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases. Nature Neuroscience. 21: 1332-1340. PMID 30250260 DOI: 10.1038/S41593-018-0235-9 |
0.514 |
|
| 2018 |
Gonzalez C, Armijo E, Bravo-Alegria J, Becerra-Calixto A, Mays CE, Soto C. Modeling amyloid beta and tau pathology in human cerebral organoids. Molecular Psychiatry. PMID 30171212 DOI: 10.1038/S41380-018-0229-8 |
0.419 |
|
| 2018 |
Dhouafli Z, Cuanalo-Contreras K, Hayouni EA, Mays CE, Soto C, Moreno-Gonzalez I. Inhibition of protein misfolding and aggregation by natural phenolic compounds. Cellular and Molecular Life Sciences : Cmls. PMID 30030591 DOI: 10.1007/S00018-018-2872-2 |
0.464 |
|
| 2018 |
Dhouafli Z, Leri M, Bucciantini M, Stefani M, Gadhoumi H, Mahjoub B, Ben Jannet H, Guillard J, Ksouri R, Saidani Tounsi M, Soto C, Hayouni EA. 1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-βaggregation and reduces amyloid cytotoxicity. Biofactors (Oxford, England). PMID 29582494 DOI: 10.1002/Biof.1422 |
0.395 |
|
| 2018 |
Pritzkow S, Morales R, Lyon A, Concha-Marambio L, Urayama A, Soto C. Efficient prion disease transmission through common environmental materials. The Journal of Biological Chemistry. PMID 29330304 DOI: 10.1074/Jbc.M117.810747 |
0.424 |
|
| 2018 |
Moreno-Gonzalez I, Edwards GA, Ruiz NG, Peter P, Morales R, Marquez M, Pumarola M, Soto C. P1-187: Aged Cattle Brain Displays Alzheimer'S-Like Pathology That Can Be Propagated In A Prion-Like Manner Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.191 |
0.352 |
|
| 2017 |
Kramm C, Pritzkow S, Lyon A, Nichols T, Morales R, Soto C. Detection of Prions in Blood of Cervids at the Asymptomatic Stage of Chronic Wasting Disease. Scientific Reports. 7: 17241. PMID 29222449 DOI: 10.1038/S41598-017-17090-X |
0.348 |
|
| 2017 |
Mukherjee A, Morales-Scheihing D, Salvadores N, Moreno-Gonzalez I, Gonzalez C, Taylor-Presse K, Mendez N, Shahnawaz M, Gaber AO, Sabek OM, Fraga DW, Soto C. Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism. The Journal of Experimental Medicine. PMID 28765400 DOI: 10.1084/Jem.20161134 |
0.635 |
|
| 2017 |
Diaz-Espinoza R, Morales R, Concha-Marambio L, Moreno-Gonzalez I, Moda F, Soto C. Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo. Molecular Psychiatry. 23: 777-788. PMID 28630454 DOI: 10.1038/Mp.2017.84 |
0.456 |
|
| 2017 |
Shahnawaz M, Park KW, Mukherjee A, Diaz-Espinoza R, Soto C. Prion-like characteristics of the bacterial protein Microcin E492. Scientific Reports. 7: 45720. PMID 28361921 DOI: 10.1038/Srep45720 |
0.638 |
|
| 2017 |
Duran-Aniotz C, Cornejo VH, Espinoza S, Ardiles ÁO, Medinas DB, Salazar C, Foley A, Gajardo I, Thielen P, Iwawaki T, Scheper W, Soto C, Palacios AG, Hoozemans JJ, Hetz C. IRE1 signaling exacerbates Alzheimer's disease pathogenesis. Acta Neuropathologica. PMID 28341998 DOI: 10.1007/S00401-017-1694-X |
0.397 |
|
| 2017 |
Park KW, Eun Kim G, Morales R, Moda F, Moreno-Gonzalez I, Concha-Marambio L, Lee AS, Hetz C, Soto C. The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo. Scientific Reports. 7: 44723. PMID 28333162 DOI: 10.1038/Srep44723 |
0.469 |
|
| 2017 |
Hoover CE, Davenport KA, Henderson DM, Denkers ND, Mathiason CK, Soto C, Zabel MD, Hoover EA. Pathways of Prion Spread during Early Chronic Wasting Disease in Deer. Journal of Virology. PMID 28250130 DOI: 10.1128/Jvi.00077-17 |
0.346 |
|
| 2017 |
Mukherjee A, Soto C. Prion-Like Protein Aggregates and Type 2 Diabetes. Cold Spring Harbor Perspectives in Medicine. PMID 28159831 DOI: 10.1101/Cshperspect.A024315 |
0.686 |
|
| 2017 |
Moreno-Gonzalez I, Edwards Iii G, Salvadores N, Shahnawaz M, Diaz-Espinoza R, Soto C. Molecular interaction between type 2 diabetes and Alzheimer's disease through cross-seeding of protein misfolding. Molecular Psychiatry. 22: 1327-1334. PMID 28044060 DOI: 10.1038/Mp.2016.230 |
0.48 |
|
| 2017 |
Moreno-Gonzalez I, Edwards GA, Marquez M, Pumarola M, Soto C. Amyloid Beta Aggregates Present In Aged Cattle Brain Accelerate Alzheimer’S Pathology Alzheimers & Dementia. 13: 310. DOI: 10.1016/J.Jalz.2017.06.244 |
0.376 |
|
| 2016 |
Armijo E, Gonzalez C, Shahnawaz M, Flores A, Davis B, Soto C. Increased susceptibility to aβ toxicity in neuronal cultures derived from familial Azheimer's disease (PSEN1-A246E) induced pluripotent stem cells. Neuroscience Letters. PMID 28034781 DOI: 10.1016/J.Neulet.2016.12.060 |
0.363 |
|
| 2016 |
Concha-Marambio L, Pritzkow S, Moda F, Tagliavini F, Ironside JW, Schulz PE, Soto C. Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease. Science Translational Medicine. 8: 370ra183. PMID 28003548 DOI: 10.1126/Scitranslmed.Aaf6188 |
0.372 |
|
| 2016 |
Shahnawaz M, Tokuda T, Waragai M, Mendez N, Ishii R, Trenkwalder C, Mollenhauer B, Soto C. Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid. Jama Neurology. PMID 27918765 DOI: 10.1001/Jamaneurol.2016.4547 |
0.421 |
|
| 2016 |
Cuanalo-Contreras K, Park KW, Mukherjee A, Millán-Pérez Peña L, Soto C. Delaying aging in Caenorhabditis elegans with protein aggregation inhibitors. Biochemical and Biophysical Research Communications. PMID 27810360 DOI: 10.1016/J.Bbrc.2016.10.143 |
0.615 |
|
| 2016 |
Urayama A, Concha-Marambio L, Khan U, Bravo-Alegria J, Kharat V, Soto C. Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo. Scientific Reports. 6: 32338. PMID 27573341 DOI: 10.1038/Srep32338 |
0.366 |
|
| 2016 |
Estrada LD, Chamorro D, Yañez MJ, Gonzalez M, Leal N, von Bernhardi R, Dulcey AE, Marugan J, Ferrer M, Soto C, Zanlungo S, Inestrosa NC, Alvarez AR. Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition. Journal of Alzheimer's Disease : Jad. PMID 27567806 DOI: 10.3233/Jad-151087 |
0.412 |
|
| 2016 |
Edwards G, Moreno-Gonzalez I, Soto C. Amyloid-beta and tau pathology following repetitive mild traumatic brain injury. Biochemical and Biophysical Research Communications. PMID 27492070 DOI: 10.1016/J.Bbrc.2016.07.123 |
0.478 |
|
| 2016 |
Mays CE, Soto C. The stress of prion disease. Brain Research. PMID 27060771 DOI: 10.1016/J.Brainres.2016.04.009 |
0.436 |
|
| 2016 |
Hu PP, Morales R, Duran-Aniotz C, Moreno-Gonzalez I, Khan U, Soto C. Role of prion replication in the strain-dependent brain regional distribution of prions. The Journal of Biological Chemistry. PMID 27056328 DOI: 10.1074/Jbc.M115.681791 |
0.343 |
|
| 2016 |
Morales R, Hu PP, Duran-Aniotz C, Moda F, Diaz-Espinoza R, Chen B, Bravo-Alegria J, Makarava N, Baskakov IV, Soto C. Strain-dependent profile of misfolded prion protein aggregates. Scientific Reports. 6: 20526. PMID 26877167 DOI: 10.1038/Srep20526 |
0.405 |
|
| 2015 |
Mukherjee A, Syeb K, Concannon J, Callegari K, Soto C, Glicksman MA. Development of a Fluorescent Quenching Based High Throughput Assay to Screen for Calcineurin Inhibitors. Plos One. 10: e0131297. PMID 26176772 DOI: 10.1371/Journal.Pone.0131297 |
0.628 |
|
| 2015 |
Torres M, Medinas DB, Matamala JM, Woehlbier U, Cornejo VH, Solda T, Andreu C, Rozas P, Matus S, Muñoz N, Vergara C, Cartier L, Soto C, Molinari M, Hetz C. The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein. The Journal of Biological Chemistry. 290: 23631-45. PMID 26170458 DOI: 10.1074/Jbc.M114.635565 |
0.44 |
|
| 2015 |
Mukherjee A, Morales-Scheihing D, Butler PC, Soto C. Type 2 diabetes as a protein misfolding disease. Trends in Molecular Medicine. 21: 439-49. PMID 25998900 DOI: 10.1016/J.Molmed.2015.04.005 |
0.671 |
|
| 2015 |
Pritzkow S, Morales R, Moda F, Khan U, Telling GC, Hoover E, Soto C. Grass plants bind, retain, uptake, and transport infectious prions. Cell Reports. 11: 1168-75. PMID 25981035 DOI: 10.1016/J.Celrep.2015.04.036 |
0.342 |
|
| 2015 |
Maheshwari A, Fischer M, Gambetti P, Parker A, Ram A, Soto C, Concha-Marambio L, Cohen Y, Belay ED, Maddox RA, Mead S, Goodman C, Kass JS, Schonberger LB, Hussein HM. Recent US Case of Variant Creutzfeldt-Jakob Disease-Global Implications. Emerging Infectious Diseases. 21: 750-9. PMID 25897712 DOI: 10.3201/Eid2105.142017 |
0.327 |
|
| 2015 |
Morales R, Bravo-Alegria J, Duran-Aniotz C, Soto C. Titration of biologically active amyloid-β seeds in a transgenic mouse model of Alzheimer's disease. Scientific Reports. 5: 9349. PMID 25879692 DOI: 10.1038/Srep09349 |
0.446 |
|
| 2015 |
Morales R, Callegari K, Soto C. Prion-like features of misfolded Aβ and tau aggregates. Virus Research. PMID 25575736 DOI: 10.1016/J.Virusres.2014.12.031 |
0.494 |
|
| 2014 |
Moda F, Gambetti P, Notari S, Concha-Marambio L, Catania M, Park KW, Maderna E, Suardi S, Haïk S, Brandel JP, Ironside J, Knight R, Tagliavini F, Soto C. Prions in the urine of patients with variant Creutzfeldt-Jakob disease. The New England Journal of Medicine. 371: 530-9. PMID 25099577 DOI: 10.1056/Nejmoa1404401 |
0.442 |
|
| 2014 |
Salvadores N, Shahnawaz M, Scarpini E, Tagliavini F, Soto C. Detection of misfolded Aβ oligomers for sensitive biochemical diagnosis of Alzheimer's disease. Cell Reports. 7: 261-8. PMID 24656814 DOI: 10.1016/J.Celrep.2014.02.031 |
0.387 |
|
| 2014 |
Duran-Aniotz C, Morales R, Moreno-Gonzalez I, Hu PP, Fedynyshyn J, Soto C. Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease. Plos One. 9: e89014. PMID 24533166 DOI: 10.1371/Journal.Pone.0089014 |
0.448 |
|
| 2014 |
Chen B, Soto C, Morales R. Peripherally administrated prions reach the brain at sub-infectious quantities in experimental hamsters. Febs Letters. 588: 795-800. PMID 24492001 DOI: 10.1016/J.Febslet.2014.01.038 |
0.384 |
|
| 2014 |
Concha-Marambio L, Diaz-Espinoza R, Soto C. The extent of protease resistance of misfolded prion protein is highly dependent on the salt concentration. The Journal of Biological Chemistry. 289: 3073-9. PMID 24338008 DOI: 10.1074/Jbc.M113.513267 |
0.39 |
|
| 2014 |
Soto C. The story of the rogue prions Nature Medicine. 20: 1089-1089. DOI: 10.1038/Nm.3718 |
0.357 |
|
| 2014 |
Morales R, Duran-Aniotz C, Bravo-Alegria J, Moreno-Gonzalez I, Soto C. PRION-LIKE PROPERTIES OF MISFOLDED AMYLOID-β AGGREGATES IN ANIMAL MODELS Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.338 |
0.376 |
|
| 2014 |
Chen B, Soto C, Morales R. Corrigendum to “Peripherally administrated prions reach the brain at sub‐infectious quantities in experimental hamsters” [FEBS Lett. 588 (2014) 795–800] Febs Letters. 588: 3308-3309. DOI: 10.1016/J.Febslet.2014.06.039 |
0.302 |
|
| 2013 |
Cuanalo-Contreras K, Mukherjee A, Soto C. Role of protein misfolding and proteostasis deficiency in protein misfolding diseases and aging. International Journal of Cell Biology. 2013: 638083. PMID 24348562 DOI: 10.1155/2013/638083 |
0.647 |
|
| 2013 |
Duran-Aniotz C, Morales R, Moreno-Gonzalez I, Hu PP, Soto C. Brains from non-Alzheimer's individuals containing amyloid deposits accelerate Aβ deposition in vivo. Acta Neuropathologica Communications. 1: 76. PMID 24252208 DOI: 10.1186/2051-5960-1-76 |
0.403 |
|
| 2013 |
Morales R, Pritzkow S, Hu PP, Duran-Aniotz C, Soto C. Lack of prion transmission by sexual or parental routes in experimentally infected hamsters. Prion. 7: 412-9. PMID 24121659 DOI: 10.4161/Pri.26747 |
0.3 |
|
| 2013 |
Morales R, Moreno-Gonzalez I, Soto C. Cross-seeding of misfolded proteins: implications for etiology and pathogenesis of protein misfolding diseases. Plos Pathogens. 9: e1003537. PMID 24068917 DOI: 10.1371/Journal.Ppat.1003537 |
0.497 |
|
| 2013 |
Moreno-Gonzalez I, Estrada LD, Sanchez-Mejias E, Soto C. Smoking exacerbates amyloid pathology in a mouse model of Alzheimer's disease. Nature Communications. 4: 1495. PMID 23422663 DOI: 10.1038/Ncomms2494 |
0.308 |
|
| 2013 |
Barria MA, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C. Correction: De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype Plos Pathogens. 9. DOI: 10.1371/Annotation/4B55946A-Edb5-4Feb-Aeb5-2Ee160394D17 |
0.541 |
|
| 2012 |
Morales R, Duran-Aniotz C, Diaz-Espinoza R, Camacho MV, Soto C. Protein misfolding cyclic amplification of infectious prions. Nature Protocols. 7: 1397-409. PMID 22743831 DOI: 10.1038/Nprot.2012.067 |
0.439 |
|
| 2012 |
Soto C. Transmissible proteins: expanding the prion heresy. Cell. 149: 968-77. PMID 22632966 DOI: 10.1016/J.Cell.2012.05.007 |
0.414 |
|
| 2012 |
Barria MA, Gonzalez-Romero D, Soto C. Cyclic amplification of prion protein misfolding. Methods in Molecular Biology (Clifton, N.J.). 849: 199-212. PMID 22528092 DOI: 10.1007/978-1-61779-551-0_14 |
0.372 |
|
| 2012 |
Diaz-Espinoza R, Soto C. High-resolution structure of infectious prion protein: the final frontier. Nature Structural & Molecular Biology. 19: 370-7. PMID 22472622 DOI: 10.1038/Nsmb.2266 |
0.422 |
|
| 2012 |
Soto C. In vivo spreading of tau pathology. Neuron. 73: 621-3. PMID 22365536 DOI: 10.1016/J.Neuron.2012.02.006 |
0.318 |
|
| 2012 |
Diaz-Espinoza R, Mukherjee A, Soto C. Kosmotropic anions promote conversion of recombinant prion protein into a PrPSc-like misfolded form. Plos One. 7: e31678. PMID 22347503 DOI: 10.1371/Journal.Pone.0031678 |
0.652 |
|
| 2012 |
Shahnawaz M, Soto C. Microcin amyloid fibrils A are reservoir of toxic oligomeric species. The Journal of Biological Chemistry. 287: 11665-76. PMID 22337880 DOI: 10.1074/Jbc.M111.282533 |
0.407 |
|
| 2012 |
Moreno-Gonzalez I, Soto C. Natural animal models of neurodegenerative protein misfolding diseases. Current Pharmaceutical Design. 18: 1148-58. PMID 22288404 DOI: 10.2174/138161212799315768 |
0.487 |
|
| 2012 |
Soto C. Animal models for neurodegenerative diseases associated to accumulation of misfolded protein aggregates. Current Pharmaceutical Design. 18: 1107. PMID 22288399 DOI: 10.2174/138161212799315803 |
0.479 |
|
| 2012 |
Morales R, Duran-Aniotz C, Castilla J, Estrada LD, Soto C. De novo induction of amyloid-β deposition in vivo. Molecular Psychiatry. 17: 1347-53. PMID 21968933 DOI: 10.1038/Mp.2011.120 |
0.428 |
|
| 2012 |
Morales R, Duran-Aniotz C, Castilla J, Estrada LD, Soto C. Erratum: De novo induction of amyloid-β deposition in vivo Molecular Psychiatry. 18: 266-266. DOI: 10.1038/Mp.2012.153 |
0.455 |
|
| 2011 |
Torres M, Encina G, Soto C, Hetz C. Abnormal calcium homeostasis and protein folding stress at the ER: A common factor in familial and infectious prion disorders. Communicative & Integrative Biology. 4: 258-61. PMID 21980554 DOI: 10.4161/Cib.4.3.15019 |
0.359 |
|
| 2011 |
Moreno-Gonzalez I, Soto C. Misfolded protein aggregates: mechanisms, structures and potential for disease transmission. Seminars in Cell & Developmental Biology. 22: 482-7. PMID 21571086 DOI: 10.1016/J.Semcdb.2011.04.002 |
0.521 |
|
| 2011 |
Urayama A, Morales R, Niehoff ML, Banks WA, Soto C. Initial fate of prions upon peripheral infection: half-life, distribution, clearance, and tissue uptake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2792-803. PMID 21555356 DOI: 10.1096/Fj.11-180729 |
0.4 |
|
| 2011 |
Mukherjee A, Soto C. Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress. Current Opinion in Cell Biology. 23: 223-30. PMID 21295458 DOI: 10.1016/J.Ceb.2010.12.006 |
0.644 |
|
| 2011 |
Barria MA, Telling GC, Gambetti P, Mastrianni JA, Soto C. Generation of a new form of human PrP(Sc) in vitro by interspecies transmission from cervid prions. The Journal of Biological Chemistry. 286: 7490-5. PMID 21209079 DOI: 10.1074/Jbc.M110.198465 |
0.431 |
|
| 2011 |
Soto C. Prion hypothesis: the end of the controversy? Trends in Biochemical Sciences. 36: 151-8. PMID 21130657 DOI: 10.1016/J.Tibs.2010.11.001 |
0.415 |
|
| 2011 |
Soto C, Satani N. The intricate mechanisms of neurodegeneration in prion diseases. Trends in Molecular Medicine. 17: 14-24. PMID 20889378 DOI: 10.1016/J.Molmed.2010.09.001 |
0.486 |
|
| 2011 |
Moreno-Gonzalez I, Estrada LD, Soto C. Smoking acelerates amyloid formation and associated neurodegenerative alterations in a transgenic mouse model of alzheimerâś disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2041 |
0.377 |
|
| 2011 |
Morales R, Duran-Aniotz C, Urayama A, Estrada LD, Morales-Scheihing D, Soto C. Induction of cerebral amyloidosis and memory impairments by blood transfusion in mice models of Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1148 |
0.325 |
|
| 2010 |
Torres M, Castillo K, Armisén R, Stutzin A, Soto C, Hetz C. Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress. Plos One. 5: e15658. PMID 21209925 DOI: 10.1371/Journal.Pone.0015658 |
0.354 |
|
| 2010 |
Mukherjee A, Morales-Scheihing D, Gonzalez-Romero D, Green K, Taglialatela G, Soto C. Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival. Plos Pathogens. 6: e1001138. PMID 20949081 DOI: 10.1371/Journal.Ppat.1001138 |
0.653 |
|
| 2010 |
Chen B, Morales R, Barria MA, Soto C. Estimating prion concentration in fluids and tissues by quantitative PMCA. Nature Methods. 7: 519-20. PMID 20512142 DOI: 10.1038/Nmeth.1465 |
0.397 |
|
| 2010 |
Angers RC, Kang HE, Napier D, Browning S, Seward T, Mathiason C, Balachandran A, McKenzie D, Castilla J, Soto C, Jewell J, Graham C, Hoover EA, Telling GC. Prion strain mutation determined by prion protein conformational compatibility and primary structure. Science (New York, N.Y.). 328: 1154-8. PMID 20466881 DOI: 10.1126/Science.1187107 |
0.357 |
|
| 2010 |
Diaz-Espinoza R, Soto C. Generation of prions in vitro and the protein-only hypothesis. Prion. 4: 53-9. PMID 20448454 DOI: 10.4161/Pri.4.2.11960 |
0.437 |
|
| 2010 |
Abid K, Morales R, Soto C. Cellular factors implicated in prion replication. Febs Letters. 584: 2409-14. PMID 20412808 DOI: 10.1016/J.Febslet.2010.04.040 |
0.375 |
|
| 2010 |
Morales R, Estrada LD, Diaz-Espinoza R, Morales-Scheihing D, Jara MC, Castilla J, Soto C. Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4528-35. PMID 20357103 DOI: 10.1523/Jneurosci.5924-09.2010 |
0.51 |
|
| 2009 |
Soto C, Martin Z. Therapeutic strategies against protein misfolding in neurodegenerative diseases. Expert Opinion On Drug Discovery. 4: 71-84. PMID 23480338 DOI: 10.1517/13543770802630455 |
0.489 |
|
| 2009 |
Morales R, Green KM, Soto C. Cross currents in protein misfolding disorders: interactions and therapy. Cns & Neurological Disorders Drug Targets. 8: 363-71. PMID 19702573 DOI: 10.2174/187152709789541998 |
0.428 |
|
| 2009 |
Chen D, Martin ZS, Soto C, Schein CH. Computational selection of inhibitors of Abeta aggregation and neuronal toxicity. Bioorganic & Medicinal Chemistry. 17: 5189-97. PMID 19540126 DOI: 10.1016/J.Bmc.2009.05.047 |
0.386 |
|
| 2009 |
Fernandez-Funez P, Casas-Tinto S, Zhang Y, Gómez-Velazquez M, Morales-Garza MA, Cepeda-Nieto AC, Castilla J, Soto C, Rincon-Limas DE. In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms. Plos Genetics. 5: e1000507. PMID 19503596 DOI: 10.1371/Journal.Pgen.1000507 |
0.469 |
|
| 2009 |
Barria MA, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C. De novo generation of infectious prions in vitro produces a new disease phenotype. Plos Pathogens. 5: e1000421. PMID 19436715 DOI: 10.1371/Journal.Ppat.1000421 |
0.668 |
|
| 2009 |
Banks WA, Robinson SM, Diaz-Espinoza R, Urayama A, Soto C. Transport of prion protein across the blood-brain barrier. Experimental Neurology. 218: 162-7. PMID 19422824 DOI: 10.1016/J.Expneurol.2009.04.025 |
0.349 |
|
| 2009 |
Piro JR, Harris BT, Nishina K, Soto C, Morales R, Rees JR, Supattapone S. Prion protein glycosylation is not required for strain-specific neurotropism. Journal of Virology. 83: 5321-8. PMID 19297485 DOI: 10.1128/Jvi.02502-08 |
0.383 |
|
| 2009 |
Soto C. Constraining the loop, releasing prion infectivity. Proceedings of the National Academy of Sciences of the United States of America. 106: 10-1. PMID 19118191 DOI: 10.1073/Pnas.0811625106 |
0.443 |
|
| 2009 |
Soto C, Morales R, Castilla J, Estrada L. O2-06-02: Transmission of Alzheimer's disease by seeding and cross-seeding Alzheimer's & Dementia. 5: P115-P115. DOI: 10.1016/J.Jalz.2009.05.362 |
0.305 |
|
| 2008 |
Morales R, Buytaert-Hoefen KA, Gonzalez-Romero D, Castilla J, Hansen ET, Hlavinka D, Goodrich RP, Soto C. Reduction of prion infectivity in packed red blood cells. Biochemical and Biophysical Research Communications. 377: 373-8. PMID 18851948 DOI: 10.1016/J.Bbrc.2008.09.141 |
0.327 |
|
| 2008 |
Soto C. Endoplasmic reticulum stress, PrP trafficking, and neurodegeneration. Developmental Cell. 15: 339-41. PMID 18804431 DOI: 10.1016/J.Devcel.2008.09.001 |
0.33 |
|
| 2008 |
Castilla J, Morales R, Saá P, Barria M, Gambetti P, Soto C. Cell-free propagation of prion strains. The Embo Journal. 27: 2557-66. PMID 18800058 DOI: 10.1038/Emboj.2008.181 |
0.388 |
|
| 2008 |
Castilla J, Gonzalez-Romero D, Saá P, Morales R, De Castro J, Soto C. Crossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions. Cell. 134: 757-68. PMID 18775309 DOI: 10.1016/J.Cell.2008.07.030 |
0.39 |
|
| 2008 |
Green KM, Castilla J, Seward TS, Napier DL, Jewell JE, Soto C, Telling GC. Accelerated high fidelity prion amplification within and across prion species barriers. Plos Pathogens. 4: e1000139. PMID 18769716 DOI: 10.1371/Journal.Ppat.1000139 |
0.391 |
|
| 2008 |
Gonzalez-Romero D, Barria MA, Leon P, Morales R, Soto C. Detection of infectious prions in urine. Febs Letters. 582: 3161-6. PMID 18706416 DOI: 10.1016/J.Febslet.2008.08.003 |
0.412 |
|
| 2008 |
Gambetti P, Dong Z, Yuan J, Xiao X, Zheng M, Alshekhlee A, Castellani R, Cohen M, Barria MA, Gonzalez-Romero D, Belay ED, Schonberger LB, Marder K, Harris C, Burke JR, ... ... Soto C, et al. A novel human disease with abnormal prion protein sensitive to protease. Annals of Neurology. 63: 697-708. PMID 18571782 DOI: 10.1002/Ana.21420 |
0.451 |
|
| 2008 |
Soto C, Estrada LD. Protein misfolding and neurodegeneration. Archives of Neurology. 65: 184-9. PMID 18268186 DOI: 10.1001/Archneurol.2007.56 |
0.512 |
|
| 2008 |
Hetz C, Lee AH, Gonzalez-Romero D, Thielen P, Castilla J, Soto C, Glimcher LH. Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 757-62. PMID 18178615 DOI: 10.1073/Pnas.0711094105 |
0.401 |
|
| 2007 |
Soto C. Reversibility of prion-induced neurodegeneration. The Lancet. Neurology. 6: 294-5. PMID 17362830 DOI: 10.1016/S1474-4422(07)70064-9 |
0.502 |
|
| 2007 |
Hetz C, Castilla J, Soto C. Perturbation of endoplasmic reticulum homeostasis facilitates prion replication. The Journal of Biological Chemistry. 282: 12725-33. PMID 17329244 DOI: 10.1074/Jbc.M611909200 |
0.409 |
|
| 2007 |
Estrada LD, Soto C. Disrupting beta-amyloid aggregation for Alzheimer disease treatment. Current Topics in Medicinal Chemistry. 7: 115-26. PMID 17266599 DOI: 10.2174/156802607779318262 |
0.458 |
|
| 2007 |
Morales R, Abid K, Soto C. The prion strain phenomenon: molecular basis and unprecedented features. Biochimica Et Biophysica Acta. 1772: 681-91. PMID 17254754 DOI: 10.1016/J.Bbadis.2006.12.006 |
0.324 |
|
| 2007 |
Richt JA, Kasinathan P, Hamir AN, Castilla J, Sathiyaseelan T, Vargas F, Sathiyaseelan J, Wu H, Matsushita H, Koster J, Kato S, Ishida I, Soto C, Robl JM, Kuroiwa Y. Production of cattle lacking prion protein. Nature Biotechnology. 25: 132-8. PMID 17195841 DOI: 10.1038/Nbt1271 |
0.447 |
|
| 2007 |
Morales R, Buytaert-Hoefen KA, Hansen ET, Hlavinka D, Goodrich R, Soto C. Reduction of Prion Infectivity in Packed Red Cells by Separation of Whole Blood and Washing of the Red Cell Fraction. Blood. 110: 2890-2890. DOI: 10.1182/Blood.V110.11.2890.2890 |
0.318 |
|
| 2006 |
Pastrana MA, Sajnani G, Onisko B, Castilla J, Morales R, Soto C, Requena JR. Isolation and characterization of a proteinase K-sensitive PrPSc fraction. Biochemistry. 45: 15710-7. PMID 17176093 DOI: 10.1021/Bi0615442 |
0.327 |
|
| 2006 |
Castilla J, Saá P, Morales R, Abid K, Maundrell K, Soto C. Protein misfolding cyclic amplification for diagnosis and prion propagation studies. Methods in Enzymology. 412: 3-21. PMID 17046648 DOI: 10.1016/S0076-6879(06)12001-7 |
0.457 |
|
| 2006 |
Saá P, Castilla J, Soto C. Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification. The Journal of Biological Chemistry. 281: 35245-52. PMID 16982620 DOI: 10.1074/Jbc.M603964200 |
0.445 |
|
| 2006 |
Estrada LD, Yowtak J, Soto C. Protein misfolding disorders and rational design of antimisfolding agents. Methods in Molecular Biology (Clifton, N.J.). 340: 277-93. PMID 16957342 DOI: 10.1385/1-59745-116-9:277 |
0.438 |
|
| 2006 |
Abid K, Soto C. The intriguing prion disorders. Cellular and Molecular Life Sciences : Cmls. 63: 2342-51. PMID 16927029 DOI: 10.1007/S00018-006-6140-5 |
0.451 |
|
| 2006 |
Estrada LD, Soto C. Inhibition of protein misfolding and aggregation by small rationally-designed peptides. Current Pharmaceutical Design. 12: 2557-67. PMID 16842178 DOI: 10.2174/138161206777698792 |
0.494 |
|
| 2006 |
Saá P, Castilla J, Soto C. Presymptomatic detection of prions in blood. Science (New York, N.Y.). 313: 92-4. PMID 16825570 DOI: 10.1126/Science.1129051 |
0.366 |
|
| 2006 |
Soto C, Estrada L, Castilla J. Amyloids, prions and the inherent infectious nature of misfolded protein aggregates. Trends in Biochemical Sciences. 31: 150-5. PMID 16473510 DOI: 10.1016/J.Tibs.2006.01.002 |
0.503 |
|
| 2006 |
Hetz CA, Soto C. Stressing out the ER: a role of the unfolded protein response in prion-related disorders. Current Molecular Medicine. 6: 37-43. PMID 16472111 DOI: 10.2174/156652406775574578 |
0.474 |
|
| 2006 |
Hetz CA, Soto C. Emerging roles of the unfolded protein response signaling in physiology and disease. Current Molecular Medicine. 6: 1. PMID 16472109 DOI: 10.2174/156652406775574532 |
0.385 |
|
| 2006 |
Soto C. Editorial [ Therapeutics for Protein Misfolding Diseases Executive Editor: Claudio Soto ] Current Pharmaceutical Design. 12: 2541-2542. DOI: 10.2174/138161206777698864 |
0.456 |
|
| 2005 |
Castilla J, Saá P, Soto C. Detection of prions in blood. Nature Medicine. 11: 982-5. PMID 16127436 DOI: 10.1038/Nm1286 |
0.351 |
|
| 2005 |
Saá P, Castilla J, Soto C. Cyclic amplification of protein misfolding and aggregation. Methods in Molecular Biology (Clifton, N.J.). 299: 53-65. PMID 15980595 DOI: 10.1385/1-59259-874-9:053 |
0.478 |
|
| 2005 |
Bieler S, Estrada L, Lagos R, Baeza M, Castilla J, Soto C. Amyloid formation modulates the biological activity of a bacterial protein. The Journal of Biological Chemistry. 280: 26880-5. PMID 15917245 DOI: 10.1074/Jbc.M502031200 |
0.497 |
|
| 2005 |
Castilla J, Saá P, Hetz C, Soto C. In vitro generation of infectious scrapie prions. Cell. 121: 195-206. PMID 15851027 DOI: 10.1016/J.Cell.2005.02.011 |
0.471 |
|
| 2005 |
Hetz C, Russelakis-Carneiro M, Wälchli S, Carboni S, Vial-Knecht E, Maundrell K, Castilla J, Soto C. The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2793-802. PMID 15772339 DOI: 10.1523/Jneurosci.4090-04.2005 |
0.442 |
|
| 2005 |
Soto C, Estrada L. Amyloid inhibitors and beta-sheet breakers. Sub-Cellular Biochemistry. 38: 351-64. PMID 15709488 DOI: 10.1007/0-387-23226-5_18 |
0.374 |
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| 2005 |
Soto C, Anderes L, Suardi S, Cardone F, Castilla J, Frossard MJ, Peano S, Saa P, Limido L, Carbonatto M, Ironside J, Torres JM, Pocchiari M, Tagliavini F. Pre-symptomatic detection of prions by cyclic amplification of protein misfolding. Febs Letters. 579: 638-42. PMID 15670821 DOI: 10.1016/J.Febslet.2004.12.035 |
0.415 |
|
| 2004 |
Russelakis-Carneiro M, Hetz C, Maundrell K, Soto C. Prion replication alters the distribution of synaptophysin and caveolin 1 in neuronal lipid rafts. The American Journal of Pathology. 165: 1839-48. PMID 15509552 DOI: 10.1016/S0002-9440(10)63439-6 |
0.393 |
|
| 2004 |
Soto C. Diagnosing prion diseases: needs, challenges and hopes. Nature Reviews. Microbiology. 2: 809-19. PMID 15378045 DOI: 10.1038/Nrmicro1003 |
0.427 |
|
| 2004 |
Castilla J, Hetz C, Soto C. Molecular mechanisms of neurotoxicity of pathological prion protein. Current Molecular Medicine. 4: 397-403. PMID 15354870 DOI: 10.2174/1566524043360654 |
0.417 |
|
| 2004 |
Soto C, Castilla J. The controversial protein-only hypothesis of prion propagation. Nature Medicine. 10: S63-7. PMID 15272271 DOI: 10.1038/Nm1069 |
0.462 |
|
| 2004 |
Banks WA, Niehoff ML, Adessi C, Soto C. Passage of murine scrapie prion protein across the mouse vascular blood-brain barrier. Biochemical and Biophysical Research Communications. 318: 125-30. PMID 15110762 DOI: 10.1016/J.Bbrc.2004.04.009 |
0.412 |
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| 2004 |
Chacón MA, BarrÃa MI, Soto C, Inestrosa NC. Beta-sheet breaker peptide prevents Abeta-induced spatial memory impairments with partial reduction of amyloid deposits. Molecular Psychiatry. 9: 953-61. PMID 15098004 DOI: 10.1038/Sj.Mp.4001516 |
0.349 |
|
| 2003 |
Hetz C, Russelakis-Carneiro M, Maundrell K, Castilla J, Soto C. Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. The Embo Journal. 22: 5435-45. PMID 14532116 DOI: 10.1093/Emboj/Cdg537 |
0.419 |
|
| 2003 |
Hetz C, Maundrell K, Soto C. Is loss of function of the prion protein the cause of prion disorders? Trends in Molecular Medicine. 9: 237-43. PMID 12829011 DOI: 10.1016/S1471-4914(03)00069-8 |
0.469 |
|
| 2003 |
Hetz C, Soto C. Protein misfolding and disease: the case of prion disorders. Cellular and Molecular Life Sciences : Cmls. 60: 133-43. PMID 12613663 DOI: 10.1007/S000180300009 |
0.486 |
|
| 2003 |
Adessi C, Frossard MJ, Boissard C, Fraga S, Bieler S, Ruckle T, Vilbois F, Robinson SM, Mutter M, Banks WA, Soto C. Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease. The Journal of Biological Chemistry. 278: 13905-11. PMID 12578830 DOI: 10.1074/Jbc.M211976200 |
0.381 |
|
| 2003 |
Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Reviews. Neuroscience. 4: 49-60. PMID 12511861 DOI: 10.1038/Nrn1007 |
0.488 |
|
| 2003 |
Hetz C, Benavent S, Bieler S, Soto C. Prion Protein Misfolding and Brain Degeneration Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 3: 137-147. DOI: 10.2174/1568013033483519 |
0.397 |
|
| 2002 |
Permanne B, Adessi C, Fraga S, Frossard MJ, Saborio GP, Soto C. Are beta-sheet breaker peptides dissolving the therapeutic problem of Alzheimer's disease? Journal of Neural Transmission. Supplementum. 293-301. PMID 12456072 DOI: 10.1007/978-3-7091-6139-5_27 |
0.309 |
|
| 2002 |
Soto C. Altering prion replication for therapy and diagnosis of transmissible spongiform encephalopathies. Biochemical Society Transactions. 30: 569-74. PMID 12196139 DOI: 10.1042/Bst0300569 |
0.441 |
|
| 2002 |
Russelakis-Carneiro M, Saborio GP, Anderes L, Soto C. Changes in the glycosylation pattern of prion protein in murine scrapie. Implications for the mechanism of neurodegeneration in prion diseases. The Journal of Biological Chemistry. 277: 36872-7. PMID 12130636 DOI: 10.1074/Jbc.M202229200 |
0.359 |
|
| 2002 |
Soto C, Saborio GP, Anderes L. Cyclic amplification of protein misfolding: application to prion-related disorders and beyond. Trends in Neurosciences. 25: 390-4. PMID 12127750 DOI: 10.1016/S0166-2236(02)02195-1 |
0.421 |
|
| 2002 |
Permanne B, Adessi C, Saborio GP, Fraga S, Frossard MJ, Van Dorpe J, Dewachter I, Banks WA, Van Leuven F, Soto C. Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 860-2. PMID 11967228 DOI: 10.1096/Fj.01-0841Fje |
0.401 |
|
| 2002 |
Adessi C, Soto C. Beta-sheet breaker strategy for the treatment of Alzheimer's disease Drug Development Research. 56: 184-193. DOI: 10.1002/Ddr.10074 |
0.439 |
|
| 2001 |
Petchanikow C, Saborio GP, Anderes L, Frossard MJ, Olmedo MI, Soto C. Biochemical and structural studies of the prion protein polymorphism. Febs Letters. 509: 451-6. PMID 11749972 DOI: 10.1016/S0014-5793(01)03147-7 |
0.429 |
|
| 2001 |
Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature. 411: 810-3. PMID 11459061 DOI: 10.1038/35081095 |
0.454 |
|
| 2001 |
Soto C. Protein misfolding and disease; protein refolding and therapy. Febs Letters. 498: 204-7. PMID 11412858 DOI: 10.1016/S0014-5793(01)02486-3 |
0.467 |
|
| 2001 |
Calero M, Pawlik M, Soto C, Castaño EM, Sigurdsson EM, Kumar A, Gallo G, Frangione B, Levy E. Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type. Journal of Neurochemistry. 77: 628-37. PMID 11299325 DOI: 10.1046/J.1471-4159.2001.00256.X |
0.316 |
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| 2001 |
Soto C, SaborÃo GP. Prions: disease propagation and disease therapy by conformational transmission. Trends in Molecular Medicine. 7: 109-14. PMID 11286781 DOI: 10.1016/S1471-4914(01)01931-1 |
0.465 |
|
| 2000 |
Soto C, Saborio GP, Permanne B. Inhibiting the conversion of soluble amyloid-beta peptide into abnormally folded amyloidogenic intermediates: relevance for Alzheimer's disease therapy. Acta Neurologica Scandinavica. Supplementum. 176: 90-5. PMID 11261811 DOI: 10.1034/j.1600-0404.2000.00313.x |
0.309 |
|
| 2000 |
Baumann MH, Kallijärvi J, Lankinen H, Soto C, Haltia M. Apolipoprotein E includes a binding site which is recognized by several amyloidogenic polypeptides. Biochemical Journal. 349: 77-84. PMID 10861213 DOI: 10.1042/0264-6021:3490077 |
0.374 |
|
| 2000 |
Yan SD, Zhu H, Zhu A, Golabek A, Du H, Roher A, Yu J, Soto C, Schmidt AM, Stern D, Kindy M. Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nature Medicine. 6: 643-51. PMID 10835680 DOI: 10.1038/76216 |
0.373 |
|
| 2000 |
Sigurdsson EM, Permanne B, Soto C, Wisniewski T, Frangione B. In vivo reversal of amyloid-beta lesions in rat brain. Journal of Neuropathology and Experimental Neurology. 59: 11-7. PMID 10744031 DOI: 10.1093/Jnen/59.1.11 |
0.366 |
|
| 2000 |
Soto C, Kascsak RJ, SaborÃo GP, Aucouturier P, Wisniewski T, Prelli F, Kascsak R, Mendez E, Harris DA, Ironside J, Tagliavini F, Carp RI, Frangione B. Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet. 355: 192-7. PMID 10675119 DOI: 10.1016/S0140-6736(99)11419-3 |
0.349 |
|
| 2000 |
Permanne BM, Saborio GP, Soto C. In vivo disrupting of amyloid deposition after injection of β-sheet breaker peptide into cerebral ventricle Neurobiology of Aging. 21: 87. DOI: 10.1016/S0197-4580(00)82617-2 |
0.305 |
|
| 1999 |
Soto C. Plaque busters: strategies to inhibit amyloid formation in Alzheimer's disease. Molecular Medicine Today. 5: 343-50. PMID 10431167 DOI: 10.1016/S1357-4310(99)01508-7 |
0.473 |
|
| 1999 |
Poduslo JF, Curran GL, Kumar A, Frangione B, Soto C. Beta-sheet breaker peptide inhibitor of Alzheimer's amyloidogenesis with increased blood-brain barrier permeability and resistance to proteolytic degradation in plasma. Journal of Neurobiology. 39: 371-82. PMID 10363910 DOI: 10.1002/(Sici)1097-4695(19990605)39:3<371::Aid-Neu4>3.0.Co;2-E |
0.37 |
|
| 1999 |
SaborÃo GP, Soto C, Kascsak RJ, Levy E, Kascsak R, Harris DA, Frangione B. Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone. Biochemical and Biophysical Research Communications. 258: 470-5. PMID 10329411 DOI: 10.1006/Bbrc.1999.0660 |
0.406 |
|
| 1999 |
Soto C. ??-Amyloid Disrupting Drugs Cns Drugs. 12: 347-356. DOI: 10.2165/00023210-199912050-00002 |
0.436 |
|
| 1998 |
Wisniewski T, Aucouturier P, Soto C, Frangione B. The prionoses and other conformational disorders. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 212-24. PMID 9818059 DOI: 10.3109/13506129809003848 |
0.491 |
|
| 1998 |
Soto C, Sigurdsson EM, Morelli L, Kumar RA, Castaño EM, Frangione B. Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nature Medicine. 4: 822-6. PMID 9662374 DOI: 10.1038/Nm0798-822 |
0.422 |
|
| 1998 |
Pappolla M, Bozner P, Soto C, Shao H, Robakis NK, Zagorski M, Frangione B, Ghiso J. Inhibition of Alzheimer beta-fibrillogenesis by melatonin. The Journal of Biological Chemistry. 273: 7185-8. PMID 9516407 DOI: 10.1074/Jbc.273.13.7185 |
0.407 |
|
| 1997 |
Permanne B, Perez C, Soto C, Frangione B, Wisniewski T. Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants. Biochemical and Biophysical Research Communications. 240: 715-20. PMID 9398632 DOI: 10.1006/Bbrc.1997.7727 |
0.419 |
|
| 1997 |
Yan SD, Fu J, Soto C, Chen X, Zhu H, Al-Mohanna F, Collison K, Zhu A, Stern E, Saido T, Tohyama M, Ogawa S, Roher A, Stern D. An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature. 389: 689-95. PMID 9338779 DOI: 10.1038/39522 |
0.406 |
|
| 1996 |
Castaño EM, Prelli F, Soto C, Beavis R, Matsubara E, Shoji M, Frangione B. The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis, Dutch type. Implications for the role of amyloid-beta 1-42 in Alzheimer's disease. The Journal of Biological Chemistry. 271: 32185-91. PMID 8943274 DOI: 10.1074/Jbc.271.50.32185 |
0.392 |
|
| 1996 |
Soto C, Kindy MS, Baumann M, Frangione B. Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochemical and Biophysical Research Communications. 226: 672-80. PMID 8831674 DOI: 10.1006/Bbrc.1996.1413 |
0.32 |
|
| 1996 |
Soto C, Golabek A, Wisniewski T, Castaño EM. Alzheimer's beta-amyloid peptide is conformationally modified by apolipoprotein E in vitro. Neuroreport. 7: 721-5. PMID 8733730 DOI: 10.1097/00001756-199602290-00010 |
0.317 |
|
| 1996 |
Matsubara E, Soto C, Governale S, Frangione B, Ghiso J. Apolipoprotein J and Alzheimer's amyloid beta solubility. The Biochemical Journal. 316: 671-9. PMID 8687416 DOI: 10.1042/Bj3160671 |
0.31 |
|
| 1996 |
Soto C, Castaño EM. The conformation of Alzheimer's beta peptide determines the rate of amyloid formation and its resistance to proteolysis. Biochemical Journal. 314: 701-707. PMID 8670088 DOI: 10.1042/Bj3140701 |
0.319 |
|
| 1996 |
Golabek AA, Soto C, Vogel T, Wisniewski T. The interaction between apolipoprotein E and Alzheimer's amyloid beta-peptide is dependent on beta-peptide conformation. The Journal of Biological Chemistry. 271: 10602-6. PMID 8631862 DOI: 10.1074/Jbc.271.18.10602 |
0.379 |
|
| 1995 |
Soto C, Castaño EM, Kumar RA, Beavis RC, Frangione B. Fibrillogenesis of synthetic amyloid-beta peptides is dependent on their initial secondary structure. Neuroscience Letters. 200: 105-8. PMID 8614555 DOI: 10.1016/0304-3940(95)12089-M |
0.369 |
|
| 1995 |
Soto C, Frangione B. Two conformational states of amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease. Neuroscience Letters. 186: 115-8. PMID 7777177 DOI: 10.1016/0304-3940(95)11299-C |
0.384 |
|
| 1995 |
Soto C, Castaño EM, Prelli F, Kumar RA, Baumann M. Apolipoprotein E increases the fibrillogenic potential of synthetic peptides derived from Alzheimer's, Gelsolin and AA amyloids Febs Letters. 371: 110-114. PMID 7672107 DOI: 10.1016/0014-5793(95)00863-5 |
0.391 |
|
| 1995 |
Castano EM, Prelli F, Wisniewski T, Golabek A, Kumar RA, Soto C, Frangione B. Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E. The Biochemical Journal. 306: 599-604. PMID 7534068 DOI: 10.1042/Bj3060599 |
0.417 |
|
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