William L. Dewey - Publications

Affiliations: 
Virginia Commonwealth University School of Medicine, Richmond, VA 
Area:
pharmacology, analgesics, opioids

266 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Obeng S, Jali A, Zheng Y, Wang H, Schwienteck K, Chen C, Stevens DL, Akbarali H, Dewey WL, Banks ML, Liu-Chen LY, Selley DE, Zhang Y. Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment. Acs Chemical Neuroscience. PMID 30758946 DOI: 10.1021/acschemneuro.9b00038  0.36
2019 Zheng Y, Obeng S, Wang H, Jali AM, Peddibhotla B, Williams D, Zou C, Stevens DL, Dewey WL, Akbarali HI, Selley DE, Zhang Y. Design, Synthesis, and Biological Evaluation of the Third Generation 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'- pyridyl)carboxamido]morphinan (NAP) Derivatives as Mu/Kappa Opioid Receptor Dual Selective Ligands. Journal of Medicinal Chemistry. PMID 30608693 DOI: 10.1021/acs.jmedchem.8b01158  0.36
2018 Poklis JL, Gonek MM, Wolf CE, Akbarali HI, Dewey WL. Analysis of carbenoxolone by ultra-performance liquid chromatography tandem mass spectrometry in mouse brain and blood after systemic administration. Biomedical Chromatography : Bmc. e4465. PMID 30548295 DOI: 10.1002/bmc.4465  0.48
2018 Obeng S, Wang H, Jali A, Stevens DL, Akbarali HI, Dewey WL, Selley DE, Zhang Y. Structure activity relationship studies of 6α- and 6β-indolylacetamidonaltrexamine derivatives as bitopic mu opioid receptor modulators and elaboration of the 'message-address concept' to comprehend their functional conversion. Acs Chemical Neuroscience. PMID 30156823 DOI: 10.1021/acschemneuro.8b00349  0.36
2018 Zheng Y, Obeng S, Wang H, Stevens DL, Komla E, Selley DE, Dewey WL, Akbarali HI, Zhang Y. Methylation Products of 6β-N-heterocyclic substituted naltrexamine derivatives as potential peripheral opioid receptor modulators. Acs Chemical Neuroscience. PMID 30001114 DOI: 10.1021/acschemneuro.8b00234  0.36
2017 Jacob JC, Poklis JL, Akbarali HI, Henderson G, Dewey WL. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442580 DOI: 10.1124/jpet.117.241083  0.48
2017 Xu GG, Zolotarskaya OY, Williams DA, Yuan Y, Selley DE, Dewey WL, Akbarali HI, Yang H, Zhang Y. Nanoconjugated NAP as a Potent and Periphery Selective Mu Opioid Receptor Modulator To Treat Opioid-Induced Constipation. Acs Medicinal Chemistry Letters. 8: 78-83. PMID 28105279 DOI: 10.1021/acsmedchemlett.6b00382  0.36
2016 Xu X, Zhang A, Halquist MS, Yuan X, Henderson SC, Dewey WL, Li PL, Li N, Zhang F. Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages. Journal of Cellular and Molecular Medicine. PMID 27629819 DOI: 10.1111/jcmm.12970  0.36
2016 Williams DA, Zheng Y, David BG, Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Selley DE, Dewey WL, Akbarali HI, Zhang Y. 6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand. Acs Chemical Neuroscience. PMID 27269866 DOI: 10.1021/acschemneuro.6b00075  0.36
2016 Xu X, Yuan X, Li N, Dewey WL, Li PL, Zhang F. Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(-/-) mice. Journal of Cellular and Molecular Medicine. PMID 26818887 DOI: 10.1111/jcmm.12788  0.36
2016 Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali HI, Banks ML, Wise LE, Cravatt BF, Lichtman AH. The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model. The Journal of Pharmacology and Experimental Therapeutics. PMID 26791602 DOI: 10.1124/jpet.115.229971  0.48
2015 Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE. 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) modulating the mu opioid receptor in a biased fashion. Acs Chemical Neuroscience. PMID 26716358 DOI: 10.1021/acschemneuro.5b00245  0.36
2015 Fitting S, Stevens DL, Khan FA, Scoggins KL, Enga RM, Beardsley PM, Knapp PE, Dewey WL, Hauser KF. Morphine tolerance and physical dependence are altered in conditional HIV-1 Tat transgenic mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26542403 DOI: 10.1124/jpet.115.226407  0.36
2015 Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Mosier PD, Kellogg GE, Dewey WL, Selley DE, Zhang Y. Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorganic & Medicinal Chemistry. 23: 1701-15. PMID 25783191 DOI: 10.1016/j.bmc.2015.02.055  0.96
2015 Fitting S, Ngwainmbi J, Kang M, Khan FA, Stevens DL, Dewey WL, Knapp PE, Hauser KF, Akbarali HI. Sensitization of enteric neurons to morphine by HIV-1 Tat protein. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 27: 468-80. PMID 25703354 DOI: 10.1111/nmo.12514  0.96
2014 Ngwainmbi J, De DD, Smith TH, El-Hage N, Fitting S, Kang M, Dewey WL, Hauser KF, Akbarali HI. Effects of HIV-1 Tat on enteric neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14243-51. PMID 25339738 DOI: 10.1523/JNEUROSCI.2283-14.2014  0.96
2014 Akbarali HI, Inkisar A, Dewey WL. Site and mechanism of morphine tolerance in the gastrointestinal tract. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 26: 1361-7. PMID 25257923 DOI: 10.1111/nmo.12443  0.96
2014 Smith TH, Ngwainmbi J, Hashimoto A, Dewey WL, Akbarali HI. Morphine dependence in single enteric neurons from the mouse colon requires deletion of β-arrestin2. Physiological Reports. 2. PMID 25194025 DOI: 10.14814/phy2.12140  0.96
2014 Maguma HT, Datta De D, Bhave S, Dewey WL, Akbarali HI. Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract. Plos One. 9: e103894. PMID 25083714 DOI: 10.1371/journal.pone.0103894  0.96
2013 Yuan Y, Zaidi SA, Elbegdorj O, Aschenbach LC, Li G, Stevens DL, Scoggins KL, Dewey WL, Selley DE, Zhang Y. Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivity. Journal of Medicinal Chemistry. 56: 9156-69. PMID 24144240 DOI: 10.1021/jm4012214  0.96
2013 Smith TH, Ngwainmbi J, Grider JR, Dewey WL, Akbarali HI. An in-vitro preparation of isolated enteric neurons and glia from the myenteric plexus of the adult mouse. Journal of Visualized Experiments : Jove. PMID 23962959 DOI: 10.3791/50688  0.96
2013 Llorente J, Withey S, Rivero G, Cunningham M, Cooke A, Saxena K, McPherson J, Oldfield S, Dewey WL, Bailey CP, Kelly E, Henderson G. Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons. Molecular Pharmacology. 84: 252-60. PMID 23716621 DOI: 10.1124/mol.113.085936  0.96
2013 Hull LC, Gabra BH, Bailey CP, Henderson G, Dewey WL. Reversal of morphine analgesic tolerance by ethanol in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 345: 512-9. PMID 23528610 DOI: 10.1124/jpet.112.202184  0.96
2013 Hawkins EG, Dewey WL, Anitha M, Srinivasan S, Grider JR, Akbarali HI. Electrophysiological characteristics of enteric neurons isolated from the immortomouse. Digestive Diseases and Sciences. 58: 1516-27. PMID 23371009 DOI: 10.1007/s10620-013-2557-5  0.96
2013 Smith TH, Grider JR, Dewey WL, Akbarali HI. Correction: Morphine decreases enteric neuron excitability via inhibition of sodium channels (PLoS ONE) Plos One. 8. DOI: 10.1371/annotation/c2d0d839-3fea-4dfd-ad78-4e4fb1271b20  0.96
2012 Yuan Y, Elbegdorj O, Chen J, Akubathini SK, Zhang F, Stevens DL, Beletskaya IO, Scoggins KL, Zhang Z, Gerk PM, Selley DE, Akbarali HI, Dewey WL, Zhang Y. Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents. Journal of Medicinal Chemistry. 55: 10118-29. PMID 23116124 DOI: 10.1021/jm301247n  0.96
2012 Smith TH, Grider JR, Dewey WL, Akbarali HI. Morphine decreases enteric neuron excitability via inhibition of sodium channels. Plos One. 7: e45251. PMID 23028881 DOI: 10.1371/journal.pone.0045251  0.96
2012 Ritter JK, Fang Y, Xia M, Li PL, Dewey WL. Contribution of acid sphingomyelinase in the periaqueductal gray region to morphine-induced analgesia in mice. Neuroreport. 23: 780-5. PMID 22825003 DOI: 10.1097/WNR.0b013e3283571757  0.96
2012 Ross GR, Lichtman A, Dewey WL, Akbarali HI. Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice. Pharmacology. 90: 55-65. PMID 22759743 DOI: 10.1159/000339076  0.96
2012 Ritter JK, Li C, Xia M, Poklis JL, Lichtman AH, Abdullah RA, Dewey WL, Li PL. Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. The Journal of Pharmacology and Experimental Therapeutics. 342: 770-9. PMID 22685343 DOI: 10.1124/jpet.112.196451  0.96
2012 Yuan Y, Stevens DL, Braithwaite A, Scoggins KL, Bilsky EJ, Akbarali HI, Dewey WL, Zhang Y. 6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 4731-4. PMID 22683223 DOI: 10.1016/j.bmcl.2012.05.075  0.96
2012 Fitting S, Scoggins KL, Xu R, Dever SM, Knapp PE, Dewey WL, Hauser KF. Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice. European Journal of Pharmacology. 689: 96-103. PMID 22659585 DOI: 10.1016/j.ejphar.2012.05.029  0.96
2012 Maguma HT, Dewey WL, Akbarali HI. Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout mice. European Journal of Pharmacology. 685: 133-40. PMID 22521552 DOI: 10.1016/j.ejphar.2012.04.001  0.96
2012 Ross GR, Gade AR, Dewey WL, Akbarali HI. Opioid-induced hypernociception is associated with hyperexcitability and altered tetrodotoxin-resistant Na+ channel function of dorsal root ganglia. American Journal of Physiology. Cell Physiology. 302: C1152-61. PMID 22189556 DOI: 10.1152/ajpcell.00171.2011  0.96
2012 Kang M, Maguma HT, Smith TH, Ross GR, Dewey WL, Akbarali HI. The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract. The Journal of Pharmacology and Experimental Therapeutics. 340: 567-76. PMID 22129596 DOI: 10.1124/jpet.111.186320  0.96
2011 Yuan Y, Li G, He H, Stevens DL, Kozak P, Scoggins KL, Mitra P, Gerk PM, Selley DE, Dewey WL, Zhang Y. Characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as novel leads to development of mu opioid receptor selective antagonists. Acs Chemical Neuroscience. 2: 346-51. PMID 22816021 DOI: 10.1021/cn2000348  0.96
2011 Hoot MR, Sim-Selley LJ, Selley DE, Scoggins KL, Dewey WL. Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus. Brain Research. 1406: 1-7. PMID 21762883 DOI: 10.1016/j.brainres.2011.06.023  0.96
2011 Dewey W. Naloxone Xpharm: the Comprehensive Pharmacology Reference. 1-6. DOI: 10.1016/B978-008055232-3.62239-1  0.96
2011 Dewey W. Buprenorphine Xpharm: the Comprehensive Pharmacology Reference. 1-8. DOI: 10.1016/B978-008055232-3.61353-4  0.96
2010 McPherson J, Rivero G, Baptist M, Llorente J, Al-Sabah S, Krasel C, Dewey WL, Bailey CP, Rosethorne EM, Charlton SJ, Henderson G, Kelly E. μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization. Molecular Pharmacology. 78: 756-66. PMID 20647394 DOI: 10.1124/mol.110.066613  0.96
2010 Hull LC, Rabender C, Gabra BH, Zhang F, Li PL, Dewey WL. Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 334: 1042-50. PMID 20551293 DOI: 10.1124/jpet.110.169243  0.96
2010 Hoot MR, Sim-Selley LJ, Poklis JL, Abdullah RA, Scoggins KL, Selley DE, Dewey WL. Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. Brain Research. 1339: 18-25. PMID 20380816 DOI: 10.1016/j.brainres.2010.03.105  0.96
2010 Hull LC, Llorente J, Gabra BH, Smith FL, Kelly E, Bailey C, Henderson G, Dewey WL. The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy. The Journal of Pharmacology and Experimental Therapeutics. 332: 1127-35. PMID 20008489 DOI: 10.1124/jpet.109.161455  0.96
2009 Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G. Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons. British Journal of Pharmacology. 158: 157-64. PMID 19309357 DOI: 10.1111/j.1476-5381.2009.00140.x  0.96
2009 Bailey CP, Llorente J, Gabra BH, Smith FL, Dewey WL, Kelly E, Henderson G. Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons. The European Journal of Neuroscience. 29: 307-18. PMID 19200236 DOI: 10.1111/j.1460-9568.2008.06573.x  0.96
2009 Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists. Journal of Medicinal Chemistry. 52: 1416-27. PMID 19199782 DOI: 10.1021/jm801272c  0.96
2009 Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Corrections to design, synthesis, and biological evaluation of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as μ opioid receptor selective antagonists (Journal of Medicinal Chemistry (2009) 52, (1416) DOI 10.1021/jm801272c) Journal of Medicinal Chemistry. 52: 8057. DOI: 10.1021/jm9016224  0.96
2008 Jia SJ, Jin S, Zhang F, Yi F, Dewey WL, Li PL. Formation and function of ceramide-enriched membrane platforms with CD38 during M1-receptor stimulation in bovine coronary arterial myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1743-52. PMID 18723763 DOI: 10.1152/ajpheart.00617.2008  0.96
2008 Ross GR, Gabra BH, Dewey WL, Akbarali HI. Morphine tolerance in the mouse ileum and colon. The Journal of Pharmacology and Experimental Therapeutics. 327: 561-72. PMID 18682567 DOI: 10.1124/jpet.108.143438  0.96
2008 Gabra BH, Bailey CP, Kelly E, Smith FL, Henderson G, Dewey WL. Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice. Brain Research. 1217: 70-7. PMID 18501877 DOI: 10.1016/j.brainres.2008.04.036  0.96
2008 Zhang F, Jin S, Yi F, Xia M, Dewey WL, Li PL. Local production of O2- by NAD(P)H oxidase in the sarcoplasmic reticulum of coronary arterial myocytes: cADPR-mediated Ca2+ regulation. Cellular Signalling. 20: 637-44. PMID 18207366 DOI: 10.1016/j.cellsig.2007.11.013  0.96
2008 Gabra BH, Smith FL, Navarro HA, Carroll FI, Dewey WL. mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo. Brain Research. 1187: 58-66. PMID 18022146 DOI: 10.1016/j.brainres.2007.10.007  0.96
2007 Gabra BH, Bailey CP, Kelly E, Sanders AV, Henderson G, Smith FL, Dewey WL. Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance. Brain Research. 1159: 86-93. PMID 17582387 DOI: 10.1016/j.brainres.2007.05.017  0.96
2007 Sim-Selley LJ, Scoggins KL, Cassidy MP, Smith LA, Dewey WL, Smith FL, Selley DE. Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance. British Journal of Pharmacology. 151: 1324-33. PMID 17572699 DOI: 10.1038/sj.bjp.0707328  0.96
2007 Carroll FI, Kotturi SV, Navarro HA, Mascarella SW, Gilmour BP, Smith FL, Gabra BH, Dewey WL. Synthesis and pharmacological evaluation of phenylethynyl[1,2,4]methyltriazines as analogues of 3-methyl-6-(phenylethynyl)pyridine. Journal of Medicinal Chemistry. 50: 3388-91. PMID 17569516 DOI: 10.1021/jm070078r  0.96
2007 Gabra BH, Kessler FK, Ritter JK, Dewey WL, Smith FL. Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia. The Journal of Pharmacology and Experimental Therapeutics. 322: 186-94. PMID 17405869 DOI: 10.1124/jpet.107.120071  0.96
2007 Smith FL, Gabra BH, Smith PA, Redwood MC, Dewey WL. Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice. Pain. 127: 129-39. PMID 16965856 DOI: 10.1016/j.pain.2006.08.009  0.96
2006 Smith FL, Javed RR, Smith PA, Dewey WL, Gabra BH. PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 54: 474-80. PMID 17056270 DOI: 10.1016/j.phrs.2006.09.007  0.96
2006 Bailey CP, Smith FL, Kelly E, Dewey WL, Henderson G. How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance? Trends in Pharmacological Sciences. 27: 558-65. PMID 17000011 DOI: 10.1016/j.tips.2006.09.006  0.96
2006 Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1230-9. PMID 16757541 DOI: 10.1124/jpet.106.104109  0.96
2006 Dalton GD, Dewey WL. Protein kinase inhibitor peptide (PKI): a family of endogenous neuropeptides that modulate neuronal cAMP-dependent protein kinase function. Neuropeptides. 40: 23-34. PMID 16442618 DOI: 10.1016/j.npep.2005.10.002  0.96
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Protein Kinase A activity is increased in mouse lumbar spinal cord but not brain following morphine antinociceptive tolerance for 15 days. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 52: 204-10. PMID 16026714 DOI: 10.1016/j.phrs.2005.03.004  0.96
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Chronic Delta9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering protein kinase A activity in mouse brain and spinal cord. Biochemical Pharmacology. 70: 152-60. PMID 15913565 DOI: 10.1016/j.bcp.2005.04.008  0.96
2005 Dalton GD, Smith FL, Smith PA, Dewey WL. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI). Neuropharmacology. 48: 648-57. PMID 15814100 DOI: 10.1016/j.neuropharm.2004.12.006  0.96
2005 Wiley JL, Smith FL, Razdan RK, Dewey WL. Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. European Journal of Pharmacology. 510: 59-68. PMID 15740725 DOI: 10.1016/j.ejphar.2005.01.006  0.96
2004 Javed RR, Dewey WL, Smith PA, Smith FL. PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice. European Journal of Pharmacology. 492: 149-57. PMID 15178359 DOI: 10.1016/j.ejphar.2004.03.061  0.96
2004 Smith FL, Smith PA, Dewey WL, Javed RR. Effects of mGlu1 and mGlu5 metabotropic glutamate antagonists to reverse morphine tolerance in mice. European Journal of Pharmacology. 492: 137-42. PMID 15178357 DOI: 10.1016/j.ejphar.2004.03.055  0.96
2003 Smith FL, Javed RR, Elzey MJ, Dewey WL. The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Research. 985: 78-88. PMID 12957370 DOI: 10.1016/S0006-8993(03)03170-6  0.96
2002 Smith FL, Javed R, Elzey MJ, Welch SP, Selley D, Sim-Selley L, Dewey WL. Prolonged reversal of morphine tolerance with no reversal of dependence by protein kinase C inhibitors. Brain Research. 958: 28-35. PMID 12468027 DOI: 10.1016/S0006-8993(02)03394-2  0.96
2000 Campbell VC, Dewey WL, Welch SP. Comparison of [(3)H]Glyburide binding with opiate analgesia, tolerance, and dependence in ICR and Swiss-Webster mice. The Journal of Pharmacology and Experimental Therapeutics. 295: 1112-9. PMID 11082447  0.96
1999 Smith FL, Lohmann AB, Dewey WL. Involvement of phospholipid signal transduction pathways in morphine tolerance in mice. British Journal of Pharmacology. 128: 220-6. PMID 10498855 DOI: 10.1038/sj.bjp.0702771  0.96
1999 Smith FL, Dombrowski DS, Dewey WL. Involvement of intracellular calcium in morphine tolerance in mice. Pharmacology, Biochemistry, and Behavior. 62: 381-8. PMID 9972707 DOI: 10.1016/S0091-3057(98)00168-3  0.96
1997 Welch SP, Smith FL, Dewey WL. Morphine tolerance-induced modulation of [3H]glyburide binding to mouse brain and spinal cord. Drug and Alcohol Dependence. 45: 47-53. PMID 9179506 DOI: 10.1016/S0376-8716(97)01343-4  0.96
1994 Pierce EF, Eastman NW, McGowan RW, Tripathi H, Dewey WL, Olson KG. Resistance exercise decreases beta-endorphin immunoreactivity. British Journal of Sports Medicine. 28: 164-6. PMID 8000813  0.96
1994 Smith FL, Brase DA, Dombrowski DS, Dewey WL. Endogenous opioids released by suspending mice by the tail selectively enhance spinal mu opioid analgesia. The Journal of Pharmacology and Experimental Therapeutics. 270: 1177-85. PMID 7932169  0.96
1994 McLaughlin CR, Dewey WL. A comparison of the antinociceptive effects of opioid agonists in neonatal and adult rats in phasic and tonic nociceptive tests. Pharmacology, Biochemistry, and Behavior. 49: 1017-23. PMID 7886070 DOI: 10.1016/0091-3057(94)90258-5  0.96
1993 McLaughlin CR, Hull JG, Edwards WH, Cramer CP, Dewey WL. Neonatal pain: a comprehensive survey of attitudes and practices. Journal of Pain and Symptom Management. 8: 7-16. PMID 8482895 DOI: 10.1016/0885-3924(93)90114-B  0.96
1993 White CW, Ward CR, Dombrowski DS, Dunlow LD, Brase DA, Dewey WL. Effect of intrathecal morphine on the fate of glucose. Comparison with effects of insulin and xanthan gum in mice. Biochemical Pharmacology. 45: 459-64. PMID 8435095 DOI: 10.1016/0006-2952(93)90083-9  0.96
1993 Smith FL, Welch SP, Dombrowski DS, Dewey WL. The role of endogenous opioids as mediators of the hypothermic effects of intrathecally administered calcium and calcitonin gene-related peptide in mice. The Journal of Pharmacology and Experimental Therapeutics. 266: 1407-15. PMID 8371146  0.96
1993 Saxen MA, Welch SP, Dewey WL. The mouse paw withdrawal assay: a method for determining the effect of calcitonin gene-related peptide on cutaneous heat nociceptive latency time. Life Sciences. 53: 397-405. PMID 8336518 DOI: 10.1016/0024-3205(93)90643-H  0.96
1993 Calabrese VP, Gruemer HD, Tripathi HL, Dewey W, Fortner CA, DeLorenzo RJ. Serum cortisol and cerebrospinal fluid beta-endorphins in status epilepticus. Their possible relation to prognosis. Archives of Neurology. 50: 689-93. PMID 8323469 DOI: 10.1001/archneur.1993.00540070009006  0.96
1993 Pierce EF, Eastman NW, Tripathi HL, Olson KG, Dewey WL. Beta-endorphin response to endurance exercise: relationship to exercise dependence. Perceptual and Motor Skills. 77: 767-70. PMID 8284151 DOI: 10.2466/pms.1993.77.3.767  0.96
1993 Natsuki R, Dewey WL. Changes in the levels of several endogenous opioid peptides in dog cerebrospinal fluid following morphine administration. ArukōRu KenkyÅ« to Yakubutsu Izon = Japanese Journal of Alcohol Studies & Drug Dependence. 28: 379-93. PMID 8267521  0.96
1993 Pierce EF, Eastman NW, Tripathi HT, Olson KG, Dewey WL. Plasma beta-endorphin immunoreactivity: response to resistance exercise. Journal of Sports Sciences. 11: 499-52. PMID 8114174 DOI: 10.1080/02640419308730019  0.96
1993 Smith FL, Dewey WL. Endogenous dynorphin modulates calcium-mediated antinociception in mice. Pharmacology, Biochemistry, and Behavior. 45: 383-91. PMID 8101006 DOI: 10.1016/0091-3057(93)90255-R  0.96
1993 Smith FL, Stevens DL, Dewey WL. Evidence that intracerebroventricular (I.C.V.) calcium stimulates spinal dynorphin release to inhibit morphine analgesia in mice Nida Research Monograph Series. 412.  0.96
1992 Myer EC, Tripathi HL, Brase DA, Dewey WL. Elevated CSF beta-endorphin immunoreactivity in Rett's syndrome: report of 158 cases and comparison with leukemic children. Neurology. 42: 357-60. PMID 1736165  0.96
1992 Welch SL, Smith F, Saxen M, Dewey WL. Effects of endogenous calcium regulating peptides on opiate actions. Nida Research Monograph. 119: 39-43. PMID 1435980  0.96
1992 Welch SP, Stevens DL, Dewey WL. A proposed mechanism of action for the antinociceptive effect of intrathecally administered calcium in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 260: 117-27. PMID 1346158  0.96
1992 Smith FL, Dewey WL. Evidence that endogenous opioids mediate the antinociceptive effects of intrathecally administered calcium in mice. The Journal of Pharmacology and Experimental Therapeutics. 262: 995-1003. PMID 1326632  0.96
1991 Tripathi HL, Eastman NW, Brase DA, Dewey WL. Effects of diving experience on submersion-induced increases in plasma levels of beta-endorphin in scuba divers. Neuropeptides. 18: 223-7. PMID 2052144 DOI: 10.1016/0143-4179(91)90151-8  0.96
1991 Tripathi HL, Eastman NW, Olson KG, Brase DA, Dewey WL. Effects of hyperbaric simulation of scuba diving pressure on plasma beta-endorphin. Pharmacology, Biochemistry, and Behavior. 38: 219-21. PMID 2017449 DOI: 10.1016/0091-3057(91)90615-9  0.96
1991 Brase DA, Ward CR, Bey PS, Dewey WL. Antagonism of the morphine-induced locomotor activation of mice by fructose: comparison with other opiates and sugars, and sugar effects on brain morphine. Life Sciences. 49: 727-34. PMID 1875782 DOI: 10.1016/0024-3205(91)90105-K  0.96
1991 Brase DA, Ward CR, Tripathi HL, Dewey WL. An insulin-independent mechanism of intrathecal morphine-induced hypoglycemia in mice: mediation through a central alpha-2 adrenergic pathway. The Journal of Pharmacology and Experimental Therapeutics. 257: 587-94. PMID 1674529  0.96
1991 Adams ML, Morris DL, Brase DA, Dewey WL. Stereoselective effect of morphine on antinociception and endogenous opioid peptide levels in plasma but not cerebrospinal fluid of dogs. Life Sciences. 48: 917-24. PMID 1671791 DOI: 10.1016/0024-3205(91)90039-E  0.96
1991 McLaughlin CR, Dewey WL, Fanselow MS. Short- and long-term factors in tolerance to morphine-induced antinociception: Single or multiple mechanisms? Psychobiology. 19: 217-222. DOI: 10.3758/BF03332071  0.96
1990 Brase DA, Singha AK, Estrada U, Lux F, Dewey WL. Hypoglycemia induced by intrathecal opioids in mice: stereospecificity, drug specificity and effect of fasting. The Journal of Pharmacology and Experimental Therapeutics. 253: 899-904. PMID 2359029  0.96
1990 Zimmerman RS, Hayes RL, Morris DL, Lyeth BG, Dewey WL, Young HF. Beta-endorphin in cerebrospinal fluid and serum after severe head injury. Neurosurgery. 26: 764-70. PMID 2352593  0.96
1990 Welch SP, Dewey WL. The activity of several peptide fragments of parathyroid hormone, alone and in combination with salmon calcitonin and morphine, in antinociceptive tests in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 252: 140-6. PMID 2299586  0.96
1990 Doyle SA, Burstein SH, Dewey WL, Welch SP. Further studies on the antinociceptive effects of delta 6-THC-7-oic acid. Agents and Actions. 31: 157-63. PMID 2178317 DOI: 10.1007/BF02003237  0.96
1990 Compton DR, Dewey WL, Martin BR. Cannabis dependence and tolerance production. Advances in Alcohol & Substance Abuse. 9: 129-47. PMID 2165734 DOI: 10.1300/J251v09n01_08  0.96
1990 Myer EC, Morris DL, Brase DA, Dewey WL, Zimmerman AW. Naltrexone therapy of apnea in children with elevated cerebrospinal fluid beta-endorphin. Annals of Neurology. 27: 75-80. PMID 2137320 DOI: 10.1002/ana.410270112  0.96
1990 Brase DA, Tripathi HL, Dewey WL. Intrathecal morphine and insulin cause hypoglycemia in mice by different mechanisms. Nida Research Monograph. 105: 549-50. PMID 1876115  0.96
1990 Welch SP, Stevens DL, Dewey WL. Differential effects of calcitonin gene-related peptide in tests utilizing thermal versus nociceptive stimuli. Nida Research Monograph. 105: 401. PMID 1876052  0.96
1989 Lux F, Han YH, Brase DA, Dewey WL. Studies on the mechanism of hypoglycemia induced by intrathecal morphine: dissociation from behavioral effects, effects of tolerance and depletion of liver glycogen. The Journal of Pharmacology and Experimental Therapeutics. 249: 688-93. PMID 2732944  0.96
1989 Tripathi HL, Dewey WL. Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice. Journal of Toxicology and Environmental Health. 26: 437-46. PMID 2709438 DOI: 10.1080/15287398909531267  0.96
1989 Welch SP, Olson KG, Stevens DL, Dewey WL. Modulation of synaptosomal free intracellular calcium in naive and morphine-tolerant mice: correlation of calcium modulation in vitro and in vivo to tolerance development. Nida Research Monograph. 95: 552-3. PMID 2561856  0.96
1989 Welch SP, Singha AK, Dewey WL. The antinociception produced by intrathecal morphine, calcium, A23187, U50,488H, [D-Ala2, N-Me-Phe4, Gly-ol]enkephalin and [D-Pen2, D-Pen5]enkephalin after intrathecal administration of calcitonin gene-related peptide in mice. The Journal of Pharmacology and Experimental Therapeutics. 251: 1-8. PMID 2552070  0.96
1989 Brase DA, Myer EC, Dewey WL. Possible hyperendorphinergic pathophysiology of the Rett syndrome. Life Sciences. 45: 359-66. PMID 2475733 DOI: 10.1016/0024-3205(89)90620-6  0.96
1989 Dewey WL. Welcome and current status of CPDD Nida Research Monograph Series. 1-5.  0.96
1989 Dewey WL. Testing for abuse liability of drugs in humans: Foreward Nida Research Monograph Series. xi.  0.96
1988 Lux F, Brase DA, Dewey WL. Antagonism of antinociception in mice by glucose and fructose: comparison of subcutaneous and intrathecal morphine. European Journal of Pharmacology. 146: 337-40. PMID 3371404 DOI: 10.1016/0014-2999(88)90312-3  0.96
1988 Lux F, Brase DA, Dewey WL. Differential effects of subcutaneous and intrathecal morphine administration on blood glucose in mice: comparison with intracerebroventricular administration. The Journal of Pharmacology and Experimental Therapeutics. 245: 187-94. PMID 3361441  0.96
1988 Welch SP, Cooper CW, Dewey WL. An investigation of the antinociceptive activity of calcitonin gene-related peptide alone and in combination with morphine: correlation to 45Ca++ uptake by synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 244: 28-33. PMID 3257266  0.96
1988 Lux F, Welch SP, Brase DA, Dewey WL. Interaction of morphine with intrathecally administered calcium and calcium antagonists: evidence for supraspinal endogenous opioid mediation of intrathecal calcium-induced antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 246: 500-7. PMID 3136242  0.96
1987 Tripathi HL, Vocci FJ, Brase DA, Dewey WL. Effects of cannabinoids on levels of acetylcholine and choline and on turnover rate of acetylcholine in various regions of the mouse brain. Alcohol and Drug Research. 7: 525-32. PMID 3620017  0.96
1987 Adams ML, Eastman NW, Tobin RP, Morris DL, Dewey WL. Increased plasma beta-endorphin immunoreactivity in scuba divers after submersion. Medicine and Science in Sports and Exercise. 19: 87-90. PMID 3574054  0.96
1987 Estrada U, Brase DA, Martin BR, Dewey WL. Cardiovascular effects of delta 9- and delta 9(11)-tetrahydrocannabinol and their interaction with epinephrine. Life Sciences. 41: 79-87. PMID 3037218 DOI: 10.1016/0024-3205(87)90559-5  0.96
1987 Myer EC, Morris DL, Adams ML, Brase DA, Dewey WL. Increased cerebrospinal fluid beta-endorphin immunoreactivity in infants with apnea and in siblings of victims of sudden infant death syndrome. The Journal of Pediatrics. 111: 660-6. PMID 2959762 DOI: 10.1016/S0022-3476(87)80239-1  0.96
1987 Young R, Glennon RA, Dewey WL. Effects of pyrazolopyridines and a triazolopyridazine on the pentobarbital discriminative stimulus. Psychopharmacology. 93: 494-7. PMID 2893416 DOI: 10.1007/BF00207241  0.96
1987 Brase DA, Han YH, Dewey WL. Effects of glucose and diabetes on binding of naloxone and dihydromorphine to opiate receptors in mouse brain. Diabetes. 36: 1173-7. PMID 2820820  0.96
1986 Welch SP, Cooper CW, Dewey WL. Antinociceptive activity of salmon calcitonin injected intraventricularly in mice: modulation of morphine antinociception. The Journal of Pharmacology and Experimental Therapeutics. 237: 54-8. PMID 3958973  0.96
1986 Aceto MD, Bagley RS, Dewey WL, Fu TC, Martin BR. The spinal cord as a major site for the antinociceptive action of nicotine in the rat. Neuropharmacology. 25: 1031-6. PMID 3774124 DOI: 10.1016/0028-3908(86)90198-X  0.96
1986 Aceto MD, Dewey WL, Portoghese PS, Takemori AE. Effects of beta-funaltrexamine (beta-FNA) on morphine dependence in rats and monkeys. European Journal of Pharmacology. 123: 387-93. PMID 3720824 DOI: 10.1016/0014-2999(86)90713-2  0.96
1986 Shook JE, Kachur JF, Brase DA, Dewey WL. Morphine dependence and diabetes. II. Alterations of normorphine potency in the guinea-pig ileum and mouse vas deferens and of ileal morphine dependence by changes in glucose concentration. The Journal of Pharmacology and Experimental Therapeutics. 237: 848-52. PMID 3712282  0.96
1986 Shook JE, Dewey WL. Morphine dependence and diabetes. I. The development of morphine dependence in streptozotocin-diabetic rats and spontaneously diabetic C57BL/KsJ mice. The Journal of Pharmacology and Experimental Therapeutics. 237: 841-7. PMID 3712281  0.96
1986 Dewey WL. Cannabinoid pharmacology. Pharmacological Reviews. 38: 151-78. PMID 3529128  0.96
1986 Adams ML, Brase DA, Welch SP, Dewey WL. The role of endogenous peptides in the action of opioid analgesics. Annals of Emergency Medicine. 15: 1030-5. PMID 3526991 DOI: 10.1016/S0196-0644(86)80124-X  0.96
1986 Welch SP, Dewey WL. A characterization of the antinociception produced by intracerebroventricular injection of 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate in mice. The Journal of Pharmacology and Experimental Therapeutics. 239: 320-6. PMID 3095536  0.96
1986 Young R, Glennon RA, Brase DA, Dewey WL. Potencies of diazepam metabolites in rats trained to discriminate diazepam. Life Sciences. 39: 17-20. PMID 3088348 DOI: 10.1016/0024-3205(86)90432-7  0.96
1986 Shook JE, Dewey WL, Burks TF. The central and peripheral effects of delta-9-tetrahydrocannabinol on gastrointestinal transit in mice. Nida Research Monograph. 67: 222-7. PMID 3018573  0.96
1985 Cobert BJ, Dewey WL, Stewart JK. Failure of branched-chain amino acids to affect synaptosomal uptake of norepinephrine and dopamine. Research Communications in Chemical Pathology and Pharmacology. 50: 455-8. PMID 4081328  0.96
1985 Kachur JF, Rosemond R, Welch S, Bowman ER, Martin BR, Brase DA, Dewey WL. Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits. Life Sciences. 37: 2549-55. PMID 4079662 DOI: 10.1016/0024-3205(85)90613-7  0.96
1985 Widman M, Tucker S, Brase DA, Dewey WL. Cholinergic agents: antinociception without morphine type dependence in rats. Life Sciences. 36: 2007-15. PMID 4039782 DOI: 10.1016/0024-3205(85)90450-3  0.96
1985 Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 28: 783-7. PMID 2989518  0.96
1985 Cobert BJ, Dewey WL, Stewart JK. Effects of branched-chain amino acids on beta-endorphin in the pituitary of the rat. Neuroscience Letters. 58: 339-42. PMID 2931626 DOI: 10.1016/0304-3940(85)90077-1  0.96
1985 Welch SP, Dewey WL. Characterization of the antinociception produced by intracerebroventricular TMB-8 (8-[N,N-diethylamino]octyl-3,4,5-trimethoxybenzoate) in mice Federation Proceedings. 44: No. 6659.  0.96
1985 Bowman ER, Tripathi HL, Dewey WL. Effects of DFP, soman and sarin on catecholamine and serotonin levels in selected brain regions of mice Federation Proceedings. 44: No. 580.  0.96
1985 Tripathi HL, Szakal AR, Dewey WL. Effects of diisopropylfluorophosphate (DFP) on behavior and cholinergic systems in mouse brain Federation Proceedings. 44: No. 581.  0.96
1985 Tagashira E, Dewey WL. Pharmacological effects of T's and blues on narcotic-induced antinociception and physical dependence on morphine Journal of Pharmacobio-Dynamics. 8: S152.  0.96
1984 Tagashira E, Kachur JF, Carter WH, Dewey WL. Potentiation of narcotic-induced antinociception by tripelennamine in morphine-tolerant and drug-naive mice. The Journal of Pharmacology and Experimental Therapeutics. 229: 214-7. PMID 6707938  0.96
1984 Shook JE, Kallman MJ, Dewey WL. The discriminative stimulus properties of the R2 isomer of viminol. Pharmacology, Biochemistry, and Behavior. 20: 59-62. PMID 6546450 DOI: 10.1016/0091-3057(84)90101-1  0.96
1984 Tagashira E, Kachur JF, Carter WH, Dewey WL. Pentazocine-tripelennamine ("T's and Blues") substitution studies in morphine-dependent rodents. The Journal of Pharmacology and Experimental Therapeutics. 231: 97-101. PMID 6541694 DOI: 10.1016/B978-008055232-3.62389-X  0.96
1984 Dewey WL. Various factors which affect the rate of development of tolerance and physical dependence to abused drugs. Nida Research Monograph. 54: 39-49. PMID 6442762  0.96
1984 Young R, Glennon RA, Dewey WL. Stereoselective stimulus effects of 3-methylflunitrazepam and pentobarbital. Life Sciences. 34: 1977-83. PMID 6328149 DOI: 10.1016/0024-3205(84)90129-2  0.96
1984 Robertson LR, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Synthesis and pharmacological activity of some 9-substituted delta 8-tetrahydrocannabinol analogues. Journal of Medicinal Chemistry. 27: 550-2. PMID 6323713  0.96
1984 Shook JE, Kallman MJ, Martin BR, Dewey WL. Characterization of the interaction of pentazocine and tripelennamine: drug discrimination and mu-receptor binding assay. Pharmacology, Biochemistry, and Behavior. 21: 877-81. PMID 6097919  0.96
1984 Martin BR, Kallman MJ, Kaempf GF, Harris LS, Dewey WL, Razdan RK. Pharmacological potency of R- and S-3'-hydroxy-delta 9-tetrahydrocannabinol: additional structural requirement for cannabinoid activity. Pharmacology, Biochemistry, and Behavior. 21: 61-5. PMID 6087379 DOI: 10.1016/0091-3057(84)90131-X  0.96
1984 Shook JE, Dewey WL. Effect of blood glucose on the development of morphine dependence Federation Proceedings. 43: no. 2671.  0.96
1984 Tagashira E, Kachur JF, Carter WH, Dewey WL. Potentiation of pentazocine-induced lethality by tripelennamine in drug native and morphine tolerant mice Federation Proceedings. 43: no. 2697.  0.96
1984 Kachur JF, Dewey WL. A possible role for a cholecystokinin-like substance in the manifestation of naloxone-induced contractions of the guinea pig ileum following chronic exposure to morphine Federation Proceedings. 43: No. 3806.  0.96
1984 Aceto MD, Dewey WL, Portoghese PC, Takemori AE. β-Funaltrexamine (β-FNA) and morphine dependence Federation Proceedings. 43: no. 2668.  0.96
1983 Welch SP, Vocci FJ, Dewey WL. Antinociceptive and lethal effects of intraventricularly administered barium and strontium: antagonism by atropine sulfate or naloxone hydrochlorine. Life Sciences. 33: 359-64. PMID 6877028  0.96
1983 Kiang JG, Dewey WL, Wei ET. Tolerance to morphine bradycardia in the rat. The Journal of Pharmacology and Experimental Therapeutics. 226: 187-91. PMID 6864538  0.96
1983 Snow AE, Dewey WL. A comparison of antinociception induced by foot shock and morphine. The Journal of Pharmacology and Experimental Therapeutics. 227: 42-50. PMID 6312021  0.96
1983 Tagashira E, Kachur JF, Dewey WL. Cross-physical dependence of combinations of pentazocine and tripelennamine with morphine Federation Proceedings. 42: No. 5133.  0.96
1983 Aceto MD, Dewey WL, Loh HH, Lee NM. Investigation of the opiate dependence liability of dynorphin fragments and α-neo-endorphin in morphine-dependent rhesus monkeys Federation Proceedings. 42: No. 2122.  0.96
1983 Poddar MK, Dewey WL. Kepone induced changes in the synaptosomal uptake and release of dopamine in corpus striatum and norepinephrine in hypothalamus Ircs Medical Science. 11: 632-633.  0.96
1982 Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species. Life Sciences. 31: 1741-3. PMID 7154834 DOI: 10.1016/0024-3205(82)90199-0  0.96
1982 Chau TT, Izazola-Conde C, Dewey WL. Evidence for the existence of peptide and nonpeptide morphine-like materials in mouse brain: effect of an analgesic intracerebroventricular dose of acetylcholine on their levels. The Journal of Pharmacology and Experimental Therapeutics. 222: 612-6. PMID 7108767  0.96
1982 Aceto MD, Dewey WL, Chang JK, Lee NM. Dynorphin-(1-13): effects in nontolerant and morphine-dependent rhesus monkeys. European Journal of Pharmacology. 83: 139-42. PMID 6889974 DOI: 10.1016/0014-2999(82)90299-0  0.96
1982 Handrick GR, Duffley RP, Lambert G, Murphy JG, Dalzell HC, Howes JF, Razdan RK, Martin BR, Harris LS, Dewey WL. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 25: 1447-50. PMID 6296389  0.96
1982 Dewey WL, Fu TC, Ohlsson A, Bowman E, Martin BR. Evidence for the release of endogenous opiates by morphine. Nida Research Monograph. 41: 60-6. PMID 6289120  0.96
1982 Ohlsson AE, Fu TC, Jones D, Martin BR, Dewey WL. Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice. The Journal of Pharmacology and Experimental Therapeutics. 221: 362-7. PMID 6281413  0.96
1982 Snow AE, Tucker SM, Dewey WL. The role of neurotransmitters in stress-induced antinociception (SIA). Pharmacology, Biochemistry, and Behavior. 16: 47-50. PMID 6120525 DOI: 10.1016/0091-3057(82)90011-9  0.96
1982 Shook JE, Kallman MJ, Dewey WL. Discriminative stimulus properties of the R2 isomer of viminol: Generalization to the morphine cue in rats Federation Proceedings. 41: 6028.  0.96
1982 Young R, Dewey WL. Differentiation of the behavioral response produced by barbiturates and benzodiazepines by the benzodiazepine antagonist RO 15-1788 Psychopharmacology. 76: No. 50.  0.96
1981 Fu TC, Dewey WL. A new technique for the in vivo bioassay of opiates and other drugs on mouse spinal cord. European Journal of Pharmacology. 74: 239-42. PMID 7327203 DOI: 10.1016/0014-2999(81)90536-7  0.96
1981 Pedigo NW, Dewey WL. Comparison of the antinociceptive activity of intraventricularly administered acetylcholine to narcotic antinociception. Neuroscience Letters. 26: 85-90. PMID 7290542 DOI: 10.1016/0304-3940(81)90430-4  0.96
1981 End DW, Carchman RA, Dewey WL. Interactions of narcotics with synaptosomal calcium transport. Biochemical Pharmacology. 30: 674-6. PMID 7271907 DOI: 10.1016/0006-2952(81)90147-7  0.96
1981 Simon GS, Dewey WL. Narcotics and diabetes. I. The effects of streptozotocin-induced diabetes on the antinociceptive potency of morphine. The Journal of Pharmacology and Experimental Therapeutics. 218: 318-23. PMID 7019415  0.96
1981 Dewey WL. Background on animal testing in the drug delivery systems program. Nida Research Monograph. 28: 69-76. PMID 6791014  0.96
1981 Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies of new compounds in the rhesus monkey (1980). Nida Research Monograph. 34: 297-326. PMID 6783944  0.96
1981 Johnson KM, Dewey WL, Bloom AS. Adrenalectomy reverses the effects of delta-9-THC on mouse brain 5-hydroxytryptamine turnover. Pharmacology. 23: 223-9. PMID 6275421  0.64
1981 Chau TT, Dewey WL. Effects of the intracerebroventricular injection of antinociceptive doses of acetylcholine on the stereospecific binding of 3H-dihydromorphine. Life Sciences. 29: 2149-56. PMID 6275221 DOI: 10.1016/0024-3205(81)90484-7  0.96
1981 Martin BR, Balster RL, Razdan RK, Harris LS, Dewey WL. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sciences. 29: 565-74. PMID 6268916 DOI: 10.1016/0024-3205(81)90434-3  0.96
1981 Lamb RG, Dewey WL. Effect of morphine exposure on mouse liver triglyceride formation. The Journal of Pharmacology and Experimental Therapeutics. 216: 496-9. PMID 6259321  0.96
1981 End DW, Carchman RA, Dewey WL. Neurochemical correlates of chlordecone neurotoxicity. Journal of Toxicology and Environmental Health. 8: 707-18. PMID 6175764 DOI: 10.1080/15287398109530107  0.96
1981 Simon GS, Borzelleca J, Dewey WL. Narcotics and diabetes. II. Streptozotocin-induced diabetes selectively alters the potency of certain narcotic analgesics. Mechanism of diabetes: morphine interaction. The Journal of Pharmacology and Experimental Therapeutics. 218: 324-9. PMID 6114167  0.96
1981 Fu TC, Welch S, Dewey WL. Comparison of antinociceptive potency of various peptides at the supraspinal and the lumbar spinal (L1) levels in the mouse Pharmacologist. 23: no. 491.  0.96
1981 Fu TC, Dewey WL. Comparative antinociceptive potency of endorphins infused into the mouse lumbar subarachnoid space Federation Proceedings. 40: 407.  0.96
1980 Fu TC, Halenda SP, Dewey WL. The effect of hypophysectomy on acupuncture analgesia in the mouse. Brain Research. 202: 33-9. PMID 7427744 DOI: 10.1016/S0006-8993(80)80032-1  0.96
1980 Poddar MK, Dewey WL. Effects of cannabinoids on catecholamine uptake and release in hypothalamic and striatal synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 214: 63-7. PMID 7391971  0.96
1980 Tripathi HL, Vocci FJ, Dewey WL. Effect of antinociceptive doses of oxotremorine on mouse brain acetylcholine turnover rate. Life Sciences. 27: 2055-62. PMID 7207008 DOI: 10.1016/0024-3205(80)90484-1  0.96
1980 Fraser HF, Gorodetzky CW, Kay DC, Yeh SY, Dewey WL. Possible influence of opioid normetabolites on the onset, magnitude and quality of the opioid abstinence syndrome Drug and Alcohol Dependence. 5: 255-272. PMID 6989579 DOI: 10.1016/0376-8716(80)90002-2  0.96
1980 Vocci FJ, Welch SP, Dewey WL. Differential effects of divalent cations, cation chelators and an ionophore (A23187) on morphine and dibutyryl guanosine 3': 5'-cyclic monophosphate antinociception. The Journal of Pharmacology and Experimental Therapeutics. 214: 463-6. PMID 6249907  0.96
1980 Alozie SO, Martin BR, Harris LS, Dewey WL. 3H-delta 9-Tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: penetration and regional distribution in rat brain. Pharmacology, Biochemistry, and Behavior. 12: 217-21. PMID 6246544 DOI: 10.1016/0091-3057(80)90359-7  0.96
1980 Fu TC, Dewey WL. Differential effects of the spinal subarachnoid infusion of morphine and an enzyme-resistant enkephalin in mice Pharmacologist. 22: 416.  0.96
1980 Snow AE, Dewey WL. Stress-induced antinociception (SIA): Antagonism by (+)- and (-)-naloxone and yohimbine and effects on opiate binding in brain regions Pharmacologist. 22: No.800.  0.96
1980 Snow AE, Tucker SM, Dewey WL. Effect of spinalectomy and d- and l-isomers of pentazocine and cyclazocine on stress-induced-antinociception Federation Proceedings. 39: 3049.  0.96
1979 Segreti A, Vocci FJ, Dewey WL. Antagonism of barium chloride lethality by atropine and naloxone analysis by a multivariate logistic model. Toxicology and Applied Pharmacology. 50: 25-30. PMID 494298 DOI: 10.1016/0041-008X(79)90488-5  0.96
1979 Fu TC, Dewey WL. Morphine antinociception: evidence for the release of endogenous substance(s). Life Sciences. 25: 53-60. PMID 481121 DOI: 10.1016/0024-3205(79)90489-2  0.96
1979 Wilson RS, May EL, Dewey WL. Some 9-hydroxycannabinoid-like compounds. Synthesis and evaluation of analgesic and behavioral properties. Journal of Medicinal Chemistry. 22: 886-8. PMID 448688  0.96
1979 Wilson RS, Martin BR, Dewey WL. Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols. Journal of Medicinal Chemistry. 22: 879-82. PMID 448686  0.96
1979 Vocci FJ, Karbowski MJ, Dewey WL. Apparent in vivo acetylcholine turnover rate in whole mouse brain: evidence for a two compartment model by two independent kinetic analyses. Journal of Neurochemistry. 32: 1417-22. PMID 438813  0.96
1979 Carchman RA, End DW, Dewey WL, Warner W. Marihuana and opiate interactions with hormonal induced systems in cell culture. Progress in Clinical and Biological Research. 27: 237-52. PMID 424432  0.96
1979 Aceto MD, Martin BR, Uwaydah IM, May EL, Harris LS, Izazola-Conde C, Dewey WL, Bradshaw TJ, Vincek WC. Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine. Journal of Medicinal Chemistry. 22: 174-7. PMID 423195  0.96
1979 Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies on new compounds in the rhesus monkey (1979). Nida Research Monograph. 27: 330-50. PMID 121356  0.96
1979 Rosecrans JA, Campbell OL, Dewey WL, Harris LS. Discriminative stimulus and neurochemical mechanism of cathinone: a preliminary study. Nida Research Monograph. 27: 328-9. PMID 121355  0.96
1979 End DW, Carchman RA, Ameen R, Dewey WL. Inhibition of rat brain mitochondrial calcium transport by chlordecone. Toxicology and Applied Pharmacology. 51: 189-96. PMID 93321 DOI: 10.1016/0041-008X(79)90021-8  0.96
1979 Simon GS, Dewey WL. Blood glucose levels and narcotic activity in mice Federation Proceedings. 38: No. 2707.  0.96
1979 Tripathi HL, Vocci FJ, Dewey WL. Effect of cannabinoids on cholinergic systems in various regions of the mouse brain Federation Proceedings. 38: No. 1915.  0.96
1979 Aceto MD, Dewey WL, Harris LS. Analgesic properties and dependence liability of clonidine Federation Proceedings. 38: No.3286.  0.96
1979 End DW, Carchman RA, Dewey WL. Disruption of rat brain synaptosomal membranes by the neurotoxic insecticide kepone Federation Proceedings. 38: No. 3238.  0.96
1978 Dewey WL, Poddar MK, Johnson KM. The effects of cannabinoids on rat brain synaptosomes. Advances in the Biosciences. 22: 343-9. PMID 756834  0.96
1978 Johnson KM, Dewey WL. The effect of delta9-tetrahydrocannabinol on the conversion of [3H]trypotphan to 5-[3H] hydroxytryptamine in the mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 207: 140-50. PMID 702335  0.96
1978 McConnell WR, Dewey WL, Harris LS, Borzelleca JF. A study of the effect of delta 9-tetrahydrocannabinol (delta 9-THC) on mammalian salivary flow. The Journal of Pharmacology and Experimental Therapeutics. 206: 567-73. PMID 702321  0.96
1978 Johnson KM, Dewey WL. Effects of delta9-THC on the synaptosomal uptake of 3H-tryptophan and 3H-choline. Pharmacology. 17: 83-7. PMID 684080 DOI: 10.1159/000136839  0.96
1978 Day AR, Carney JM, Rosecrans JA, Dewey WL, Freer RJ. Synthesis of two enzyme resistant enkephalin analogs possessing enhanced analgesic activity. Research Communications in Chemical Pathology and Pharmacology. 20: 59-68. PMID 663409  0.96
1978 Bloom AS, Johnson KM, Dewey WL. The effects of cannabinoids on body temperature and brain catecholamine synthesis. Research Communications in Chemical Pathology and Pharmacology. 20: 51-7. PMID 663408  0.96
1978 Patrick GA, Dewey WL, Huger FP, Daves ED, Harris LS. Disposition of morphine in chronically infused rats: relationship to antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 205: 556-62. PMID 660529  0.92
1978 Johnson KM, Dewey WL, Ritter KS, Beckner JS. Cannabinoid effects on plasma corticosterone and uptake of 3H-corticosterone by mouse brain. European Journal of Pharmacology. 47: 303-10. PMID 631183  0.88
1978 Widman M, Rosin D, Dewey WL. Effects of divalent cations, lanthanum, cation chelators and an ionophore on acetylcholine antinociception. The Journal of Pharmacology and Experimental Therapeutics. 205: 311-8. PMID 347052  0.96
1978 Vocci FJ, Petty SK, Dewey WL. Antinociceptive action of the butyryl derivatives of cyclic guanosine 3':5'-monophosphate. The Journal of Pharmacology and Experimental Therapeutics. 207: 892-8. PMID 215745  0.96
1978 Lujan M, Chau-Pham TT, Aceto MD, Dewey WL. The effect of sodium ion on antinociception and opiate binding in vivo. Life Sciences. 23: 1431-9. PMID 213670  0.76
1978 Bloom AS, Dewey WL. A comparison of some pharmacological actions of morphine and delta9-tetrahydrocannabinol in the mouse. Psychopharmacology. 57: 243-8. PMID 97703  0.44
1978 Martin BR, Montgomery J, Dewey WL, Harris LS. Alterations in the pharmacokinetics of 3H-delta9-tetrahydrocannabinol in mice by bacterial endotoxin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 282-7. PMID 26549  0.96
1977 Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Research Communications in Chemical Pathology and Pharmacology. 17: 457-70. PMID 897339  0.96
1977 Adams MD, Earnhardt JT, Martin BR, Harris LS, Dewey WL, Razdan RK. A cannabinoid with cardiovascular activity but no overt behavioral effects. Experientia. 33: 1204-5. PMID 891878  1
1977 Ford RD, Balster RL, Dewey WL, Beckner JS. delta 9-THC and 11-OH-delta 9-THC: behavioral effects and relationship to plasma and brain levels. Life Sciences. 20: 1993-2003. PMID 881943  0.88
1977 Bloom AS, Dewey WL, Harris LS, Brosius KK. 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. The Journal of Pharmacology and Experimental Therapeutics. 200: 263-70. PMID 839438  0.96
1977 Martin BR, Dewey WL, Aceto MD, Adams MD, Earnhardt JT, Carney JM. A potent antinociceptive cannabinoid which lacks opiate substitution properties in monkeys. Research Communications in Chemical Pathology and Pharmacology. 16: 187-90. PMID 402685  0.96
1977 Martin BR, Dewey WL, Chau-Pham T, Prnage AJ. Interactions of thyrotropin releasing hormone and morphine sulfate in rodents. Life Sciences. 20: 715-22. PMID 402526  1
1977 Bradley SG, Munson AE, Dewey WL, Harris LS. Enhanced susceptibility of mice to combinations of delta 9-tetrahydrocannabinol and live or killed gram-negative bacteria. Infection and Immunity. 17: 325-9. PMID 330405  0.96
1976 Dionne RA, Dewey WL, Joy E. A survey of the teaching of pain control at the predoctoral level. Anesthesia Progress. 23: 152-4. PMID 19598503  0.96
1976 Razdan RK, Howes JF, Uliss DB, Dalzell HC, Handrick GR, Dewey WL. (-)-8beta-hydroxymethyl-delta1-tetrahydrocannabinol: a novel physiologically active analog of delta1-tetrahydrocannabinol. Experientia. 32: 416-7. PMID 1269636  0.72
1976 Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol tissue and subcellular distribution in the central nervous system and tissue distribution in peripheral organs of tolerant and nontolerant dogs. The Journal of Pharmacology and Experimental Therapeutics. 196: 128-44. PMID 1246007  0.96
1976 Johnson KM, Dewey WL, Ho BT. In vitro alteration of the subcellular distribution of 3H-reserpine in the rat forebrain by delta 9-tetrahydrocannabinol. Research Communications in Chemical Pathology and Pharmacology. 15: 655-71. PMID 1005913  0.96
1976 Atkinson ER, Battista SP, Ary IE, Richardson DG, Harris LS, Dewey WL. Derivatives of apomorphine and of other N-substituted norapomorphines. Journal of Pharmaceutical Sciences. 65: 1682-5. PMID 994002  0.92
1976 Day AR, Luján M, Dewey WL, Harris LS, Radding JA, Freer RJ. Structure-activity relationships of enkephalins in the stimulated guinea pig ileum. Research Communications in Chemical Pathology and Pharmacology. 14: 597-603. PMID 959662  0.92
1976 Johnson KM, Ho BT, Dewey WL. Effects of delta9-tetrahydrocannabinol on neurotransmitter accumulation and release mechanisms in rat forebrain synaptosomes. Life Sciences. 19: 347-56. PMID 957874 DOI: 10.1016/0024-3205(76)90038-2  0.96
1976 Johnson KM, Dewey WL, Harris LS. Some structural requirements for inhibition of high-affinity synaptosomal serotonin uptake by cannabinoids. Molecular Pharmacology. 12: 345-52. PMID 934055  0.96
1976 Dewey WL, Johnson KM, Bloom AS. Interactions of active constituents of marihuana with other drugs in the neuron. Annals of the New York Academy of Sciences. 281: 190-7. PMID 798522  0.64
1976 Bloom AS, Dewey WL, Harris LS, Brosius KK. The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines. The Journal of Pharmacology and Experimental Therapeutics. 198: 33-41. PMID 6793  0.96
1976 Adams MD, Earnhardt JT, Dewey WL, Harris LS. Vasoconstrictor actions of delta8- and delta9-tetrahydrocannabinol in the rat. The Journal of Pharmacology and Experimental Therapeutics. 196: 649-56. PMID 4606  0.96
1975 Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacology, Biochemistry, and Behavior. 3: 849-53. PMID 1208625 DOI: 10.1016/S0090-3752(76)80023-3  0.96
1975 Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA. Antineoplastic activity of cannabinoids. Journal of the National Cancer Institute. 55: 597-602. PMID 1159836  0.92
1975 Spaulding TC, Dewey WL. Some effects of the behaviorally active drug, phenitrone, a purported hashish and LSD antagonist, on brain noradrenergic and serotonergic systems. Research Communications in Chemical Pathology and Pharmacology. 11: 503-6. PMID 1153889  0.96
1975 Patrick GA, Dewey WL, Spaulding TC, Harris LS. Relationship of brain morphine levels to analgesic activity in acutely treated mice and rats and in pellet implanted mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 876-83. PMID 1151736  0.96
1975 Pedigo NW, Dewey WL, Harris LS. Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 845-52. PMID 1151733  0.96
1975 Dewey WL, Cocolas G, Daves E, Harris LS. Stereospecificity of intraventricularly administered acetylmethylcholine antinociception. Life Sciences. 17: 9-10. PMID 1143014 DOI: 10.1016/0024-3205(75)90224-6  0.96
1975 Chipkin RE, Dewey WL, Harris LS, Lowenthal W. Effect of propranolol on antinociceptive and withdrawal characteristics of morphine. Pharmacology, Biochemistry, and Behavior. 3: 843-7. PMID 1800 DOI: 10.1016/0091-3057(75)90115-X  0.96
1974 Spaulding TC, Dewey WL. The effects of phenitrone, a reported hashish antagonist, on the overt behavior of cats. Research Communications in Chemical Pathology and Pharmacology. 7: 347-52. PMID 4818377  0.96
1973 Kosersky DS, Dewey WL, Harris LS. Antipyretic, analgesic and anti-inflammatory effects of delta 9-tetrahydrocannabinol in the rat. European Journal of Pharmacology. 24: 1-7. PMID 4756165 DOI: 10.1016/0014-2999(73)90107-6  0.96
1973 Chau TT, Dewey WL, Harris LS. Mechanism of the synergistic lethality between pentazocine and vasopressin in the rat. The Journal of Pharmacology and Experimental Therapeutics. 186: 288-96. PMID 4719781  0.96
1973 Turk RF, Dewey WL, Harris LS. Excretion of trans- 9 -tetrahydrocannabinol and its metabolites in intact and bile duct-cannulated rats. Journal of Pharmaceutical Sciences. 62: 737-40. PMID 4705677  0.96
1973 Dewey WL, Tucker LS, Prange A. Some behavioral and toxicological effects of amyl nitrite. Research Communications in Chemical Pathology and Pharmacology. 5: 889-92. PMID 4701280  0.96
1973 Williams BO, Eckel FM, Dewey WL. The need for an adverse drug reaction prediction and prevention program. American Journal of Hospital Pharmacy. 30: 124-7. PMID 4690466  0.96
1973 Dewey WL, McMillan DE, Harris LS, Turk RF. Distribution of radioactivity in brain of tolerant and nontolerant pigeons treated with 3 H- 9 -tetrahydrocannabinol. Biochemical Pharmacology. 22: 399-405. PMID 4687135  0.92
1973 McMillan DE, Dewey WL, Turk RF, Harris LS, McNeil JH. Blood levels of 3 H- 9 -tetrahydrocannabinol and its metabolites in tolerant and nontolerant pigeons. Biochemical Pharmacology. 22: 383-97. PMID 4687134  0.92
1972 Dewey WL, Harris LS, Kennedy JS. Some pharmacological and toxicological effects of 1-trans- 8 and 1-trans- 9 -tetrahydrocannabinol in laboratory rodents. Archives Internationales De Pharmacodynamie Et De ThéRapie. 196: 133-45. PMID 5059359  0.96
1972 Dewey WL, Jenkins J, O'Rourke T, Harris LS. The effects of chronic administration of trans- 9 -tetrahydrocannabinol on behavior and the cardiovascular system of dogs. Archives Internationales De Pharmacodynamie Et De ThéRapie. 198: 118-31. PMID 5053234  0.96
1972 Zitko BA, Howes JF, Razdan RK, Dalzell BC, Dalzell HC, Sheehan JC, Pars HG, Dewey WL, Harris LS. Water-soluble derivatives of 1 -tetrahydrocannabinol. Science (New York, N.Y.). 177: 442-4. PMID 5043146  0.96
1972 Spaulding TC, Ford RD, Dewey WL, McMillan DE, Harris LS. Some pharmacological effects of phenitrone and its interaction with 9 -THC. European Journal of Pharmacology. 19: 310-7. PMID 4640854 DOI: 10.1016/0014-2999(72)90096-9  0.96
1971 Cocolas GH, Robinson EC, Dewey WL, Spaulding TC. Preparation and activity of -substituted acetylcholine iodides. Journal of Pharmaceutical Sciences. 60: 1749-52. PMID 5133939  0.96
1970 Howes JF, Harris LS, Dewey WL. The effect of morphine, nalorphine, naloxone, pentazocine, cyclazocine and oxotremorine on the synthesis and release of acetylcholine by mouse cerebral cortex slices in vitro. Archives Internationales De Pharmacodynamie Et De ThéRapie. 184: 267-76. PMID 5453231  0.96
1970 Dewey WL, Harris LS, Howes JF, Kennedy JS, Granchelli FE, Pars HG, Razdan RK. Pharmacology of some marijuana constituents and 2 heterocyclic analogues. Nature. 226: 1265-7. PMID 5422606  0.92
1970 Cocolas GH, Robinson EC, Dewey WL. A comparison of some stereochemical requirements of the acetylcholinesterase and muscarinic receptor areas. Journal of Medicinal Chemistry. 13: 299-301. PMID 5418506  0.96
1970 Dewey WL, Harris LS, Howes JF, Nuite JA. The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests. The Journal of Pharmacology and Experimental Therapeutics. 175: 435-42. PMID 4394803  0.92
1970 Dewey WL, Peng TC, Harris LS. The effect of 1-trans-delta 9-tetrahydrocannabinol on the hypothalamo-hypophyseal-adrenal axis of rats. European Journal of Pharmacology. 12: 382-4. PMID 4322071 DOI: 10.1016/0014-2999(70)90094-4  0.96
1969 Howes JF, Harris LS, Dewey WL, Voyda CA. Brain acetylcholine levels and inhibition of the tail-flick reflex in mice. The Journal of Pharmacology and Experimental Therapeutics. 169: 23-8. PMID 5804609  0.96
1969 Dewey WL, Harris LS, Howes JF, Kennedy JS, Nuite JA, Hayhurst V. The effects of narcotic-antagonist analgesics on rat brain cholinesterases. Archives Internationales De Pharmacodynamie Et De ThéRapie. 182: 471-80. PMID 5371206  0.92
1969 Harris LS, Dewey WL, Howes JF, Kennedy JS, Pars H. Narcotic-antagonist analgesics: interactions with cholinergic systems. The Journal of Pharmacology and Experimental Therapeutics. 169: 17-22. PMID 4389919  0.92
1969 Dewey WL, Snyder JW, Harris LS, Howes JF. The effect of narcotics and narcotic antagonists on the tail-flick response in spinal mice. The Journal of Pharmacy and Pharmacology. 21: 548-50. PMID 4389723  0.96
1968 Dewey WL, Malone MH. Pharmacologic and toxicologic evaluation of 2-(N-tetradecyl-N-ethylamino)-2-methyl-1,3-propanediol hydrochloride, an inhibitor of intestinal absorption. Toxicology and Applied Pharmacology. 12: 115-31. PMID 5660805  0.96
1967 Harris LS, Pierson AK, Dembinski JR, Dewey WL. The pharmacology of (minus)-3-hydroxy-N-cyclopropylmethylmorphinan (cyclorphan). Archives Internationales De Pharmacodynamie Et De ThéRapie. 165: 112-26. PMID 4382141  0.92
Show low-probability matches.