Stephen Dewhurst, PhD - Publications

Affiliations: 
Microbiology and Immunology  University of Rochester Medical Center, Rochester, NY, United States 
Area:
HIV-1, influenza A virus

160 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Simpson SR, Singh MV, Dewhurst S, Schifitto G, Maggirwar SB. Platelets function as an acute viral reservoir during HIV-1 infection by harboring virus and T-cell complex formation. Blood Advances. 4: 4512-4521. PMID 32946568 DOI: 10.1182/Bloodadvances.2020002420  0.643
2020 Piekna-Przybylska D, Bambara RA, Maggirwar SB, Dewhurst S. G-quadruplex ligands targeting telomeres do not inhibit HIV promoter activity and cooperate with latency reversing agents in killing latently infected cells. Cell Cycle (Georgetown, Tex.). 1-16. PMID 32807015 DOI: 10.1080/15384101.2020.1796268  0.649
2019 Rodriguez L, Blanco-Lobo P, Reilly EC, Maehigashi T, Nogales A, Smith A, Topham DJ, Dewhurst S, Kim B, Martínez-Sobrido L. Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines. Viruses. 11. PMID 31658679 DOI: 10.3390/V11100928  0.309
2018 Chamberlain J, Sortino K, Sethna P, Bae A, Lanier R, Bambara RA, Dewhurst S. Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via Both Non-Obligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus. Antimicrobial Agents and Chemotherapy. PMID 30397065 DOI: 10.1128/Aac.01925-18  0.324
2018 Mathew E, Zhu H, Connelly SM, Sullivan MA, Brewer MG, Piepenbrink MS, Kobie JJ, Dewhurst S, Dumont ME. Display of the HIV envelope protein at the yeast cell surface for immunogen development. Plos One. 13: e0205756. PMID 30335821 DOI: 10.1371/Journal.Pone.0205756  0.366
2017 Sheik DA, Dewhurst S, Yang J. Natural Seminal Amyloids as Targets for Development of Synthetic Inhibitors of HIV Transmission. Accounts of Chemical Research. PMID 28809479 DOI: 10.1021/Acs.Accounts.7B00154  0.386
2017 Hilimire TA, Chamberlain JM, Anokhina V, Bennett RP, Swart O, Myers JR, Ashton JM, Stewart RA, Featherston AL, Gates K, Helms ED, Smith HC, Dewhurst S, Miller BL. HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi Drug-Resistant HIV in Human Cells. Acs Chemical Biology. PMID 28448121 DOI: 10.1021/Acschembio.7B00052  0.379
2017 Mattiacio JL, Brewer M, Dewhurst S. Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform. Methods in Molecular Biology (Clifton, N.J.). 1581: 245-253. PMID 28374253 DOI: 10.1007/978-1-4939-6869-5_14  0.392
2017 Sheik DA, Chamberlain JM, Brooks LR, Clark ML, Kim YH, Leriche G, Kubiak CP, Dewhurst S, Yang J. Hydrophobic Nanoparticles Reduce the β-sheet content of SEVI Amyloid Fibrils and Inhibit SEVI-Enhanced HIV Infectivity. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28207276 DOI: 10.1021/Acs.Langmuir.6B04295  0.355
2017 Brewer MG, DiPiazza A, Acklin J, Feng C, Sant AJ, Dewhurst S. Nanoparticles decorated with viral antigens are more immunogenic at low surface density. Vaccine. PMID 28057386 DOI: 10.1016/J.Vaccine.2016.12.049  0.315
2016 Nishimura C, Polesskaya O, Dewhurst S, Silva JN. Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation. Journal of Visualized Experiments : Jove. PMID 26863270 DOI: 10.3791/53582  0.381
2016 Lu N, Silva JN, Gu Y, Wu H, Gelbard HA, Dewhurst S, Miao H. Capillary extraction by detecting polarity in circular profiles Iet Image Processing. 10: 339-348. DOI: 10.1049/Iet-Ipr.2015.0069  0.518
2015 Puccini JM, Marker DF, Fitzgerald T, Barbieri J, Kim CS, Miller-Rhodes P, Lu SM, Dewhurst S, Gelbard HA. Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5271-83. PMID 25834052 DOI: 10.1523/Jneurosci.0650-14.2015  0.637
2015 Sheik DA, Brooks L, Frantzen K, Dewhurst S, Yang J. Inhibition of the enhancement of infection of human immunodeficiency virus by semen-derived enhancer of virus infection using amyloid-targeting polymeric nanoparticles. Acs Nano. 9: 1829-36. PMID 25619867 DOI: 10.1021/Nn5067254  0.423
2014 Rhoo KH, Granger M, Sur J, Feng C, Gelbard HA, Dewhurst S, Polesskaya O. Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model. Plos One. 9: e108487. PMID 25264786 DOI: 10.1371/Journal.Pone.0108487  0.538
2014 Ying B, Tollefson AE, Spencer JF, Balakrishnan L, Dewhurst S, Capella C, Buller RM, Toth K, Wold WS. Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters. Antimicrobial Agents and Chemotherapy. 58: 7171-81. PMID 25224011 DOI: 10.1128/Aac.03860-14  0.345
2014 Nogales A, Baker SF, Ortiz-Riaño E, Dewhurst S, Topham DJ, Martínez-Sobrido L. Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine development. Journal of Virology. 88: 10525-40. PMID 24965472 DOI: 10.1128/Jvi.01565-14  0.331
2014 Lewis CA, Dewhurst S, McMahon JM, Bunce CA, Keefer MC, Alio AP. Theoretical model of critical issues in informed consent in HIV vaccine trials. Aids Care. 26: 1452-60. PMID 24865892 DOI: 10.1080/09540121.2014.920074  0.31
2014 Silva JN, Polesskaya O, Wei HS, Rasheed IY, Chamberlain JM, Nishimura C, Feng C, Dewhurst S. Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity. Microcirculation (New York, N.Y. : 1994). 21: 664-76. PMID 24813724 DOI: 10.1111/Micc.12145  0.371
2014 Polesskaya O, Wong C, Lebron L, Chamberlain JM, Gelbard HA, Goodfellow V, Kim M, Daiss JL, Dewhurst S. MLK3 regulates fMLP-stimulated neutrophil motility. Molecular Immunology. 58: 214-22. PMID 24389043 DOI: 10.1016/J.Molimm.2013.11.016  0.587
2014 Domm W, Brewer M, Baker SF, Feng C, Martínez-Sobrido L, Treanor J, Dewhurst S. Use of bacteriophage particles displaying influenza virus hemagglutinin for the detection of hemagglutination-inhibition antibodies. Journal of Virological Methods. 197: 47-50. PMID 24316333 DOI: 10.1016/J.Jviromet.2013.11.018  0.336
2013 Alcéna DC, Kobie JJ, Kaminski DA, Rosenberg AF, Mattiacio JL, Brewer M, Dewhurst S, Dykes C, Jin X, Keefer MC, Sanz I. 9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles. Plos One. 8: e85098. PMID 24386452 DOI: 10.1371/Journal.Pone.0085098  0.4
2013 Mapstone M, Hilton TN, Yang H, Guido JJ, Luque AE, Hall WJ, Dewhurst S, Shah K. Poor Aerobic Fitness May Contribute to Cognitive Decline in HIV-infected Older Adults. Aging and Disease. 4: 311-9. PMID 24307964 DOI: 10.14336/Ad.2013.0400311  0.331
2013 Goodfellow VS, Loweth CJ, Ravula SB, Wiemann T, Nguyen T, Xu Y, Todd DE, Sheppard D, Pollack S, Polesskaya O, Marker DF, Dewhurst S, Gelbard HA. Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. Journal of Medicinal Chemistry. 56: 8032-48. PMID 24044867 DOI: 10.1021/Jm401094T  0.592
2013 Easterhoff D, DiMaio JT, Liyanage W, Lo CW, Bae W, Doran TM, Smrcka A, Nilsson BL, Dewhurst S. Fluorescence detection of cationic amyloid fibrils in human semen. Bioorganic & Medicinal Chemistry Letters. 23: 5199-202. PMID 23910594 DOI: 10.1016/J.Bmcl.2013.06.097  0.727
2013 Marker DF, Tremblay MÈ, Puccini JM, Barbieri J, Gantz Marker MA, Loweth CJ, Muly EC, Lu SM, Goodfellow VS, Dewhurst S, Gelbard HA. The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9998-10010. PMID 23761895 DOI: 10.1523/Jneurosci.0598-13.2013  0.642
2013 Ma Q, Gelbard HA, Maggirwar SB, Dewhurst S, Gendelman HE, Peterson DR, DiFrancesco R, Hochreiter JS, Morse GD, Schifitto G. Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients. Journal of Neurovirology. 19: 254-60. PMID 23737347 DOI: 10.1007/S13365-013-0172-Z  0.733
2013 Lu N, Silva J, Gu Y, Gerber S, Wu H, Gelbard H, Dewhurst S, Miao H. Directional Histogram Ratio at Random Probes: A Local Thresholding Criterion for Capillary Images. Pattern Recognition. 46: 1933-1948. PMID 23525856 DOI: 10.1016/J.Patcog.2013.01.011  0.52
2013 Arany S, Benoit DS, Dewhurst S, Ovitt CE. Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1182-94. PMID 23511246 DOI: 10.1038/Mt.2013.42  0.308
2013 Easterhoff D, Ontiveros F, Brooks LR, Kim Y, Ross B, Silva JN, Olsen JS, Feng C, Hardy DJ, Dunman PM, Dewhurst S. Semen-derived enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against vaginal infection by a sexually transmitted bacterial pathogen. Antimicrobial Agents and Chemotherapy. 57: 2443-50. PMID 23507280 DOI: 10.1128/Aac.02464-12  0.741
2013 Sullivan MA, Brooks LR, Weidenborner P, Domm W, Mattiacio J, Xu Q, Tiberio M, Wentworth T, Kobie J, Bryk P, Zheng B, Murphy M, Sanz I, Dewhurst S. Anti-idiotypic monobodies derived from a fibronectin scaffold. Biochemistry. 52: 1802-13. PMID 23394681 DOI: 10.1021/Bi3016668  0.323
2013 Rojas AV, Easterhoff D, DiMaio JT, Dewhurst S, Grossfield A, Miao H, Nilsson BL. 147Characterizing the conformational space of two disordered peptides in different solutions Journal of Biomolecular Structure and Dynamics. 31: 95-95. DOI: 10.1080/07391102.2013.786389  0.722
2012 Silva J, Polesskaya O, Knight W, Zheng JT, Granger M, Lopez T, Ontiveros F, Feng C, Yan C, Kasischke KA, Dewhurst S. Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5. Journal of Neuroinflammation. 9: 253. PMID 23167821 DOI: 10.1186/1742-2094-9-253  0.336
2012 Capella C, Beltejar MJ, Brown C, Fong V, Daddacha W, Kim B, Dewhurst S. Selective modification of adenovirus replication can be achieved through rational mutagenesis of the adenovirus type 5 DNA polymerase. Journal of Virology. 86: 10484-93. PMID 22811532 DOI: 10.1128/Jvi.00739-12  0.769
2012 Kobie JJ, Alcena DC, Zheng B, Bryk P, Mattiacio JL, Brewer M, Labranche C, Young FM, Dewhurst S, Montefiori DC, Rosenberg AF, Feng C, Jin X, Keefer MC, Sanz I. 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity. Plos One. 7: e35356. PMID 22530008 DOI: 10.1371/Journal.Pone.0035356  0.383
2012 Olsen JS, DiMaio JT, Doran TM, Brown C, Nilsson BL, Dewhurst S. Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide. The Journal of Biological Chemistry. 287: 11842-9. PMID 22354963 DOI: 10.1074/Jbc.M111.314336  0.318
2012 Capule CC, Brown C, Olsen JS, Dewhurst S, Yang J. Oligovalent amyloid-binding agents reduce SEVI-mediated enhancement of HIV-1 infection. Journal of the American Chemical Society. 134: 905-8. PMID 22239120 DOI: 10.1021/Ja210931B  0.429
2011 Fong V, Osterbur M, Capella C, Kim YE, Hine C, Gorbunova V, Seluanov A, Dewhurst S. Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells. Plos One. 6: e28714. PMID 22174876 DOI: 10.1371/Journal.Pone.0028714  0.756
2011 Olsen JS, Easterhoff D, Dewhurst S. Advances in HIV microbicide development. Future Medicinal Chemistry. 3: 2101-16. PMID 22098355 DOI: 10.4155/Fmc.11.153  0.759
2011 Lu SM, Tremblay MÈ, King IL, Qi J, Reynolds HM, Marker DF, Varrone JJ, Majewska AK, Dewhurst S, Gelbard HA. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. Plos One. 6: e23915. PMID 21912650 DOI: 10.1371/Journal.Pone.0023915  0.626
2011 Domm W, Brooks L, Chung HL, Feng C, Bowers WJ, Watson G, McGrath JL, Dewhurst S. Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier. Vaccine. 29: 7080-9. PMID 21801777 DOI: 10.1016/J.Vaccine.2011.07.008  0.432
2011 Cao S, Wu C, Yang Y, Sniderhan LF, Maggirwar SB, Dewhurst S, Lu Y. Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS. Journal of Neuroinflammation. 8: 48. PMID 21569583 DOI: 10.1186/1742-2094-8-48  0.691
2011 Bussey KA, Desmet EA, Mattiacio JL, Hamilton A, Bradel-Tretheway B, Bussey HE, Kim B, Dewhurst S, Takimoto T. PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells. Journal of Virology. 85: 7020-8. PMID 21561908 DOI: 10.1128/Jvi.00522-11  0.321
2011 Easterhoff D, DiMaio JT, Doran TM, Dewhurst S, Nilsson BL. Enhancement of HIV-1 infectivity by simple, self-assembling modular peptides. Biophysical Journal. 100: 1325-34. PMID 21354406 DOI: 10.1016/J.Bpj.2011.01.037  0.757
2011 Mattiacio J, Walter S, Brewer M, Domm W, Friedman AE, Dewhurst S. Dense display of HIV-1 envelope spikes on the lambda phage scaffold does not result in the generation of improved antibody responses to HIV-1 Env. Vaccine. 29: 2637-47. PMID 21310193 DOI: 10.1016/J.Vaccine.2011.01.038  0.408
2010 Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD, Dewhurst S. Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure. Hearing Research. 270: 21-7. PMID 20971179 DOI: 10.1016/J.Heares.2010.10.008  0.698
2010 Gelbard HA, Dewhurst S, Maggirwar SB, Kiebala M, Polesskaya O, Gendelman HE. Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 392-8. PMID 20880503 DOI: 10.1016/J.Nurt.2010.08.001  0.743
2010 Olsen JS, Brown C, Capule CC, Rubinshtein M, Doran TM, Srivastava RK, Feng C, Nilsson BL, Yang J, Dewhurst S. Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection. The Journal of Biological Chemistry. 285: 35488-96. PMID 20833717 DOI: 10.1074/Jbc.M110.163659  0.421
2010 Gorantla S, Makarov E, Finke-Dwyer J, Gebhart CL, Domm W, Dewhurst S, Gendelman HE, Poluektova LY. CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 7082-91. PMID 20495069 DOI: 10.4049/Jimmunol.1000438  0.406
2010 Aggarwal S, Bradel-Tretheway B, Takimoto T, Dewhurst S, Kim B. Biochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complex. Plos One. 5: e10372. PMID 20454455 DOI: 10.1371/Journal.Pone.0010372  0.321
2010 Love TM, Thurston SW, Keefer MC, Dewhurst S, Lee HY. Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences. Journal of Virology. 84: 5802-14. PMID 20335256 DOI: 10.1128/Jvi.00117-10  0.35
2010 Desmet EA, Hollenbaugh JA, Sime PJ, Wright TW, Topham DJ, Sant AJ, Takimoto T, Dewhurst S, Maggirwar SB. Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells. Virology. 400: 224-32. PMID 20185156 DOI: 10.1016/J.Virol.2010.02.001  0.621
2010 Eggert D, Dash PK, Gorantla S, Dou H, Schifitto G, Maggirwar SB, Dewhurst S, Poluektova L, Gelbard HA, Gendelman HE. Neuroprotective activities of CEP-1347 in models of neuroAIDS. Journal of Immunology (Baltimore, Md. : 1950). 184: 746-56. PMID 19966207 DOI: 10.4049/Jimmunol.0902962  0.753
2009 Bimber BN, Chugh P, Giorgi EE, Kim B, Almudevar AL, Dewhurst S, O'Connor DH, Lee HY. Nef gene evolution from a single transmitted strain in acute SIV infection. Retrovirology. 6: 57. PMID 19505314 DOI: 10.1186/1742-4690-6-57  0.388
2009 Schifitto G, Zhong J, Gill D, Peterson DR, Gaugh MD, Zhu T, Tivarus M, Cruttenden K, Maggirwar SB, Gendelman HE, Dewhurst S, Gelbard HA. Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment. Journal of Neurovirology. 15: 176-86. PMID 19306230 DOI: 10.1080/13550280902758973  0.725
2009 Volcy K, Dewhurst S. Proteasome inhibitors enhance bacteriophage lambda (lambda) mediated gene transfer in mammalian cells. Virology. 384: 77-87. PMID 19064273 DOI: 10.1016/J.Virol.2008.11.019  0.794
2008 Norman JP, Perry SW, Reynolds HM, Kiebala M, De Mesy Bentley KL, Trejo M, Volsky DJ, Maggirwar SB, Dewhurst S, Masliah E, Gelbard HA. HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization. Plos One. 3: e3731. PMID 19009018 DOI: 10.1371/Journal.Pone.0003731  0.783
2008 Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy. Retrovirology. 5: 11. PMID 18237430 DOI: 10.1186/1742-4690-5-11  0.67
2008 Sapinoro R, Volcy K, Rodrigo WW, Schlesinger JJ, Dewhurst S. Fc receptor-mediated, antibody-dependent enhancement of bacteriophage lambda-mediated gene transfer in mammalian cells. Virology. 373: 274-86. PMID 18191979 DOI: 10.1016/J.Virol.2007.12.013  0.778
2007 Dewhurst S, Maggirwar SB, Schifitto G, Gendelman HE, Gelbard HA. Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 93-6. PMID 18040831 DOI: 10.1007/S11481-006-9051-1  0.743
2007 Sapinoro R, Maguire CA, Burgess A, Dewhurst S. Enhanced transduction of dendritic cells by FcgammaRI-targeted adenovirus vectors. The Journal of Gene Medicine. 9: 1033-45. PMID 17966114 DOI: 10.1002/Jgm.1112  0.795
2007 Duke CM, Maguire CA, Keefer MC, Federoff HJ, Bowers WJ, Dewhurst S. HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime. Vaccine. 25: 7410-21. PMID 17868958 DOI: 10.1016/J.Vaccine.2007.08.015  0.759
2007 Santos K, Sanfilippo CM, Narrow WC, Casey AE, Rodriguez-Colon SM, McDermott MP, Federoff HJ, Bowers WJ, Dewhurst S. Infectivity of herpes simplex virus type-1 (HSV-1) amplicon vectors in dendritic cells is determined by the helper virus strain used for packaging. Journal of Virological Methods. 145: 37-46. PMID 17606303 DOI: 10.1016/J.Jviromet.2007.05.013  0.327
2007 Lankes HA, Zanghi CN, Santos K, Capella C, Duke CM, Dewhurst S. In vivo gene delivery and expression by bacteriophage lambda vectors. Journal of Applied Microbiology. 102: 1337-49. PMID 17448169 DOI: 10.1111/J.1365-2672.2006.03182.X  0.793
2007 Zanghi CN, Sapinoro R, Bradel-Tretheway B, Dewhurst S. A tractable method for simultaneous modifications to the head and tail of bacteriophage lambda and its application to enhancing phage-mediated gene delivery. Nucleic Acids Research. 35: e59. PMID 17392341 DOI: 10.1093/Nar/Gkm146  0.793
2007 Sui Z, Sniderhan LF, Schifitto G, Phipps RP, Gelbard HA, Dewhurst S, Maggirwar SB. Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia. Journal of Immunology (Baltimore, Md. : 1950). 178: 3226-36. PMID 17312171 DOI: 10.4049/Jimmunol.178.5.3226  0.748
2007 Santos K, Simon DA, Conway E, Bowers WJ, Mitra S, Foster TH, Lugade A, Lord EM, Federoff HJ, Dewhurst S, Frelinger JG. Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. Human Gene Therapy. 18: 93-105. PMID 17298238 DOI: 10.1089/Hum.2006.082  0.42
2007 Malboeuf CM, Simon DA, Lee YE, Lankes HA, Dewhurst S, Frelinger JG, Rose RC. Human papillomavirus-like particles mediate functional delivery of plasmid DNA to antigen presenting cells in vivo. Vaccine. 25: 3270-6. PMID 17293010 DOI: 10.1016/J.Vaccine.2007.01.067  0.647
2007 Gorantla S, Sneller H, Walters L, Sharp JG, Pirruccello SJ, West JT, Wood C, Dewhurst S, Gendelman HE, Poluektova L. Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice. Journal of Virology. 81: 2700-12. PMID 17182671 DOI: 10.1128/Jvi.02010-06  0.405
2007 Chugh P, Fan S, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line. Journal of Molecular Biology. 366: 67-81. PMID 17157319 DOI: 10.1016/J.Jmb.2006.11.011  0.69
2007 Santos K, Duke CM, Rodriguez-Colon SM, Dakwar A, Fan S, Keefer MC, Federoff HJ, Frelinger JG, Bowers WJ, Dewhurst S. Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag. Vaccine. 25: 1634-46. PMID 17145123 DOI: 10.1016/J.Vaccine.2006.11.004  0.784
2006 Sui Z, Sniderhan LF, Fan S, Kazmierczak K, Reisinger E, Kovács AD, Potash MJ, Dewhurst S, Gelbard HA, Maggirwar SB. Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons. The European Journal of Neuroscience. 23: 2623-34. PMID 16817865 DOI: 10.1111/J.1460-9568.2006.04813.X  0.754
2006 Santos K, Duke CM, Dewhurst S. Amplicons as vaccine vectors. Current Gene Therapy. 6: 383-92. PMID 16787189 DOI: 10.2174/156652306777592009  0.749
2006 Sui Z, Fan S, Sniderhan L, Reisinger E, Litzburg A, Schifitto G, Gelbard HA, Dewhurst S, Maggirwar SB. Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation. Journal of Immunology (Baltimore, Md. : 1950). 177: 702-11. PMID 16785569 DOI: 10.4049/Jimmunol.177.1.702  0.747
2006 Hall CB, Caserta MT, Schnabel KC, McDermott MP, Lofthus GK, Carnahan JA, Gilbert LM, Dewhurst S. Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6. The Journal of Infectious Diseases. 193: 1063-9. PMID 16544246 DOI: 10.1086/503434  0.308
2006 Maguire CA, Sapinoro R, Girgis N, Rodriguez-Colon SM, Ramirez SH, Williams J, Dewhurst S. Recombinant adenovirus type 5 vectors that target DC-SIGN, ChemR23 and alpha(v)beta3 integrin efficiently transduce human dendritic cells and enhance presentation of vectored antigens. Vaccine. 24: 671-82. PMID 16154247 DOI: 10.1016/J.Vaccine.2005.08.038  0.784
2006 Zeng L, Planelles V, Sui Z, Gartner S, Maggirwar SB, Dewhurst S, Ye L, Nerurkar VR, Yanagihara R, Lu Y. HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1. The Journal of Gene Medicine. 8: 18-28. PMID 16142830 DOI: 10.1002/Jgm.825  0.699
2006 Dewhurst S, Bradel-Tretheway B. Molecular Testing for HHV-6 Infection Perspectives in Medical Virology. 12: 105-117. DOI: 10.1016/S0168-7069(06)12008-X  0.344
2005 Zanghi CN, Lankes HA, Bradel-Tretheway B, Wegman J, Dewhurst S. A simple method for displaying recalcitrant proteins on the surface of bacteriophage lambda. Nucleic Acids Research. 33: e160. PMID 16224099 DOI: 10.1093/Nar/Gni158  0.621
2005 Dou H, Ellison B, Bradley J, Kasiyanov A, Poluektova LY, Xiong H, Maggirwar S, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8375-85. PMID 16162919 DOI: 10.1523/Jneurosci.2164-05.2005  0.735
2005 Zhen Z, Bradel-Tretheway B, Sumagin S, Bidlack JM, Dewhurst S. The human herpesvirus 6 G protein-coupled receptor homolog U51 positively regulates virus replication and enhances cell-cell fusion in vitro. Journal of Virology. 79: 11914-24. PMID 16140767 DOI: 10.1128/Jvi.79.18.11914-11924.2005  0.659
2005 Perry SW, Norman JP, Litzburg A, Zhang D, Dewhurst S, Gelbard HA. HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 174: 4333-44. PMID 15778398 DOI: 10.4049/Jimmunol.174.7.4333  0.628
2005 Jin N, Kovács AD, Sui Z, Dewhurst S, Maggirwar SB. Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death. Neuropharmacology. 48: 576-83. PMID 15755485 DOI: 10.1016/J.Neuropharm.2004.11.010  0.609
2005 Fan S, Maguire CA, Ramirez SH, Bradel-Tretheway B, Sapinoro R, Sui Z, Chakraborty-Sett S, Dewhurst S. Valproic acid enhances gene expression from viral gene transfer vectors. Journal of Virological Methods. 125: 23-33. PMID 15737413 DOI: 10.1016/J.Jviromet.2004.11.023  0.79
2005 Gorantla S, Santos K, Meyer V, Dewhurst S, Bowers WJ, Federoff HJ, Gendelman HE, Poluektova L. Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge. Journal of Virology. 79: 2124-32. PMID 15681415 DOI: 10.1128/Jvi.79.4.2124-2132.2005  0.453
2005 Sapinoro RE, Burgess APH, Dewhurst S. 533. Enhanced Transduction of Dendritic Cells by FCgRI-Targeted Adenovirus Vectors|[gamma]| Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.073  0.804
2004 Renda MJ, Bradel-Tretheway B, Planelles V, Bambara RA, Dewhurst S. Inhibition of HIV type 1 replication using lentiviral-mediated delivery of mutant tRNA(Lys3)A58U. Aids Research and Human Retroviruses. 20: 1324-34. PMID 15650425 DOI: 10.1089/Aid.2004.20.1324  0.423
2004 Fan S, Ramirez SH, Garcia TM, Dewhurst S. Dishevelled promotes neurite outgrowth in neuronal differentiating neuroblastoma 2A cells, via a DIX-domain dependent pathway. Brain Research. Molecular Brain Research. 132: 38-50. PMID 15548427 DOI: 10.1016/J.Molbrainres.2004.09.003  0.644
2004 Hall CB, Caserta MT, Schnabel KC, Boettrich C, McDermott MP, Lofthus GK, Carnahan JA, Dewhurst S. Congenital infections with human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7). The Journal of Pediatrics. 145: 472-7. PMID 15480369 DOI: 10.1016/J.Jpeds.2004.06.017  0.317
2004 Diamond TL, Roshal M, Jamburuthugoda VK, Reynolds HM, Merriam AR, Lee KY, Balakrishnan M, Bambara RA, Planelles V, Dewhurst S, Kim B. Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase. The Journal of Biological Chemistry. 279: 51545-53. PMID 15452123 DOI: 10.1074/Jbc.M408573200  0.454
2004 Ramirez SH, Fan S, Maguire CA, Perry S, Hardiek K, Ramkumar V, Gelbard HA, Dewhurst S, Maggirwar SB. Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal. Journal of Neuroscience Research. 77: 258-69. PMID 15211592 DOI: 10.1002/Jnr.20150  0.775
2004 Zhen Z, Bradel-Tretheway BG, Dewhurst S, Bidlack JM. Transient overexpression of kappa and mu opioid receptors using recombinant adenovirus vectors. Journal of Neuroscience Methods. 136: 133-9. PMID 15183265 DOI: 10.1016/J.Jneumeth.2004.01.009  0.617
2004 Latchney LR, Fallon MA, Culp DJ, Gelbard HA, Dewhurst S. Immunohistochemical assessment of fractalkine, inflammatory cells, and human herpesvirus 7 in human salivary glands. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 671-81. PMID 15100244 DOI: 10.1177/002215540405200511  0.628
2003 Lu Y, Liu C, Zeng L, Lin Z, Dewhurst S, Gartner S, Planelles V. Efficient gene transfer into human monocyte-derived macrophages using defective lentiviral vectors Cellular and Molecular Biology (Noisy-Le-Grand, France). 49: 1151-1156. PMID 14682398  0.322
2003 Dou H, Birusingh K, Faraci J, Gorantla S, Poluektova LY, Maggirwar SB, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9162-70. PMID 14534250 DOI: 10.1523/Jneurosci.23-27-09162.2003  0.762
2003 Bradel-Tretheway BG, Zhen Z, Dewhurst S. Effects of codon-optimization on protein expression by the human herpesvirus 6 and 7 U51 open reading frame. Journal of Virological Methods. 111: 145-56. PMID 12880930 DOI: 10.1016/S0166-0934(03)00173-3  0.628
2003 Wang X, Messerle M, Sapinoro R, Santos K, Hocknell PK, Jin X, Dewhurst S. Murine cytomegalovirus abortively infects human dendritic cells, leading to expression and presentation of virally vectored genes. Journal of Virology. 77: 7182-92. PMID 12805417 DOI: 10.1128/Jvi.77.13.7182-7192.2003  0.8
2003 Richards JL, Abend JR, Miller ML, Chakraborty-Sett S, Dewhurst S, Whetter LE. A peptide containing a novel FPGN CD40-binding sequence enhances adenoviral infection of murine and human dendritic cells. European Journal of Biochemistry / Febs. 270: 2287-94. PMID 12752448 DOI: 10.1046/J.1432-1033.2003.03596.X  0.601
2003 Wang X, Wiley RD, Evans TG, Bowers WJ, Federoff HJ, Dewhurst S. Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming. Vaccine. 21: 2288-97. PMID 12744859 DOI: 10.1016/S0264-410X(03)00099-9  0.363
2003 Richards J, Miller M, Abend J, Koide A, Koide S, Dewhurst S. Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human alphavbeta3 integrin. Journal of Molecular Biology. 326: 1475-88. PMID 12595259 DOI: 10.1016/S0022-2836(03)00082-2  0.582
2002 Perry SW, Dewhurst S, Bellizzi MJ, Gelbard HA. Tumor necrosis factor-alpha in normal and diseased brain: Conflicting effects via intraneuronal receptor crosstalk? Journal of Neurovirology. 8: 611-24. PMID 12476354 DOI: 10.1080/13550280290101021  0.553
2002 Hocknell PK, Wiley RD, Wang X, Evans TG, Bowers WJ, Hanke T, Federoff HJ, Dewhurst S. Expression of human immunodeficiency virus type 1 gp120 from herpes simplex virus type 1-derived amplicons results in potent, specific, and durable cellular and humoral immune responses. Journal of Virology. 76: 5565-80. PMID 11991985 DOI: 10.1128/Jvi.76.11.5565-5580.2002  0.796
2001 Skrincosky D, Willis RA, Hocknell PK, Frelinger JG, Mirandola P, Wang X, Dewhurst S. Epitope mapping of human herpesvirus-7 gp65 using monoclonal antibodies. Archives of Virology. 146: 1705-22. PMID 11699957 DOI: 10.1007/S007050170058  0.774
2001 Ramirez SH, Sanchez JF, Dimitri CA, Gelbard HA, Dewhurst S, Maggirwar SB. Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. Journal of Neurochemistry. 78: 874-89. PMID 11520908 DOI: 10.1046/J.1471-4159.2001.00467.X  0.802
2001 Tong N, Sanchez JF, Maggirwar SB, Ramirez SH, Guo H, Dewhurst S, Gelbard HA. Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. The European Journal of Neuroscience. 13: 1913-22. PMID 11403684 DOI: 10.1046/J.0953-816X.2001.01572.X  0.789
2000 Bal HP, Chroboczek J, Schoehn G, Ruigrok RWH, Dewhurst S. Adenovirus type 7 penton: Purification of soluble pentamers from Escherichia coli and development of an integrin-dependent gene delivery system European Journal of Biochemistry. 267: 6074-6081. PMID 10998069 DOI: 10.1046/J.1432-1327.2000.01684.X  0.346
2000 Skrincosky D, Hocknell P, Whetter L, Secchiero P, Chandran B, Dewhurst S. Identification and analysis of a novel heparin-binding glycoprotein encoded by human herpesvirus 7 Journal of Virology. 74: 4530-4540. PMID 10775589 DOI: 10.1128/Jvi.74.10.4530-4540.2000  0.789
2000 Maggirwar SB, Ramirez S, Tong N, Gelbard HA, Dewhurst S. Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells. Journal of Neurochemistry. 74: 527-39. PMID 10646503 DOI: 10.1046/J.1471-4159.2000.740527.X  0.769
2000 Tong N, Perry SW, Zhang Q, James HJ, Guo H, Brooks A, Bal H, Kinnear SA, Fine S, Epstein LG, Dairaghi D, Schall TJ, Gendelman HE, Dewhurst S, Sharer LR, et al. Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 164: 1333-9. PMID 10640747 DOI: 10.4049/Jimmunol.164.3.1333  0.649
1999 Norton RA, Caserta MT, Hall CB, Schnabel K, Hocknell P, Dewhurst S. Detection of human herpesvirus 6 by reverse transcription-PCR Journal of Clinical Microbiology. 37: 3672-3675. PMID 10523572 DOI: 10.1128/Jcm.37.11.3672-3675.1999  0.778
1999 Hodge S, De Rosayro J, Glenn A, Ojukwu IC, Dewhurst S, McClure HM, Bischofberger N, Anderson DC, Klumpp SA, Novembre FJ. Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy, protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj Journal of Virology. 73: 8630-8639. PMID 10482616 DOI: 10.1128/Jvi.73.10.8630-8639.1999  0.375
1999 Maggirwar SB, Tong N, Ramirez S, Gelbard HA, Dewhurst S. HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity. Journal of Neurochemistry. 73: 578-86. PMID 10428053 DOI: 10.1046/J.1471-4159.1999.0730578.X  0.792
1999 Whetter LE, Ojukwu IC, Novembre FJ, Dewhurst S. Pathogenesis of simian immunodeficiency virus infection Journal of General Virology. 80: 1557-1568. PMID 10423122 DOI: 10.1099/0022-1317-80-7-1557  0.357
1999 Fine SM, Maggirwar SB, Elliott PR, Epstein LG, Gelbard HA, Dewhurst S. Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia. Journal of Neuroimmunology. 95: 55-64. PMID 10229115 DOI: 10.1016/S0165-5728(98)00267-7  0.726
1999 Norton RA, Caserta MT, Hall CB, Schnabel K, Hocknell P, Dewhurst S. Detection of Human Herpesvirus 6 by Reverse Transcription-PCR Journal of Clinical Microbiology. 37: 3672-3675. DOI: 10.1128/jcm.37.11.3672-3675.1999  0.779
1998 Hodge S, Novembre FJ, Whetter L, Gelbard HA, Dewhurst S. Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14. Virology. 252: 354-63. PMID 9878614 DOI: 10.1006/Viro.1998.9477  0.639
1998 Rotola A, Ravaioli T, Gonelli A, Dewhurst S, Cassai E, Di Luca D. U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture. Proceedings of the National Academy of Sciences of the United States of America. 95: 13911-6. PMID 9811900 DOI: 10.1073/Pnas.95.23.13911  0.391
1998 Deng SX, Panahian N, James H, Gelbard HA, Federoff HJ, Dewhurst S, Epstein LG. Luciferase: a sensitive and quantitative probe for blood-brain barrier disruption. Journal of Neuroscience Methods. 83: 159-64. PMID 9765129 DOI: 10.1016/S0165-0270(98)00077-6  0.553
1998 Hodge S, Novembre FJ, Dewhurst S. Endogenous tumor necrosis factor-α contributes to lymphoproliferation induced by simian immunodeficiency virus variant, SIVsmmPBj14 Immunology Letters. 63: 49-51. PMID 9719438 DOI: 10.1016/S0165-2478(98)00050-9  0.367
1998 New DR, Maggirwar SB, Epstein LG, Dewhurst S, Gelbard HA. HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism. The Journal of Biological Chemistry. 273: 17852-8. PMID 9651389 DOI: 10.1074/Jbc.273.28.17852  0.75
1998 Whetter L, Novembre FJ, Saucier M, Gummuluru S, Dewhurst S. Costimulatory pathways in lymphocyte proliferation induced by the simian immunodeficiency virus SIVsmmPBj14 Journal of Virology. 72: 6155-6158. PMID 9621081 DOI: 10.1128/Jvi.72.7.6155-6158.1998  0.381
1998 Saucier M, Hodge S, Dewhurst S, Gibson T, Gibson JP, McClure HM, Novembre FJ. The tyrosine-17 residue of Nef in SIVsmmPBj14 is required for acute pathogenesis and contributes to replication in macrophages Virology. 244: 261-272. PMID 9601497 DOI: 10.1006/Viro.1998.9133  0.359
1998 Bulboaca GH, Deng H, Dewhurst S, Calos MP. Telomeric sequences from human herpesvirus 6 do not mediate nuclear retention of episomal DNA in human cells Archives of Virology. 143: 563-570. PMID 9572556 DOI: 10.1007/S007050050312  0.318
1998 Deng H, Dewhurst S. Functional Identification and Analysis of cis-Acting Sequences Which Mediate Genome Cleavage and Packaging in Human Herpesvirus 6 Journal of Virology. 72: 320-329. PMID 9420230 DOI: 10.1128/Jvi.72.1.320-329.1998  0.31
1998 Maggirwar SB, Sarmiere PD, Dewhurst S, Freeman RS. Nerve Growth Factor-Dependent Activation of NF-κB Contributes to Survival of Sympathetic Neurons The Journal of Neuroscience. 18: 10356-10365. DOI: 10.1523/Jneurosci.18-24-10356.1998  0.607
1997 Dewhurst S, Skrincosky D, Loon Nv. Human herpesvirus 7. Expert Reviews in Molecular Medicine. 1: 1-10. PMID 14585127 DOI: 10.1017/S1462399497000112  0.343
1997 Krajewski S, James HJ, Ross J, Blumberg BM, Epstein LG, Gendelman HE, Gummuluru S, Dewhurst S, Sharer LR, Reed JC, Gelbard HA. Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis. Neuropathology and Applied Neurobiology. 23: 242-53. PMID 9223134 DOI: 10.1111/J.1365-2990.1997.Tb01208.X  0.651
1997 Loon NV, Dykes C, Deng H, Dominguez G, Nicholas J, Dewhurst S. Identification and Analysis of a Lytic-Phase Origin of DNA Replication in Human Herpesvirus 7 Journal of Virology. 71: 3279-3284. PMID 9060695 DOI: 10.1128/Jvi.71.4.3279-3284.1997  0.333
1996 Gummuluru S, Novembre FJ, Lewis M, Gelbard HA, Dewhurst S. Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14. Virology. 225: 21-32. PMID 8918530 DOI: 10.1006/Viro.1996.0571  0.636
1996 Dewhurst S, Sander DM, Sgro JY. Resources for HIV/AIDS on the Internet. Molecular Medicine Today. 2: 52-7. PMID 8796856 DOI: 10.1016/1357-4310(96)88735-1  0.34
1996 Dewhurst S, Gelbard HA, Fine SM. Neuropathogenesis of AIDS. Molecular Medicine Today. 2: 16-23. PMID 8796847 DOI: 10.1016/1357-4310(96)88754-5  0.637
1996 Fine SM, Angel RA, Perry SW, Epstein LG, Rothstein JD, Dewhurst S, Gelbard HA. Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. The Journal of Biological Chemistry. 271: 15303-6. PMID 8663435 DOI: 10.1074/Jbc.271.26.15303  0.644
1996 Gummuluru S, Novembre FJ, Seshi B, Dewhurst S. Sivsmmpbj14 induces expression of a mucosal integrin on macaque lymphocytes Virology. 215: 97-100. PMID 8553590 DOI: 10.1006/Viro.1996.0010  0.381
1995 Saito Y, Sharer LR, Dewhurst S, Blumberg BM, Hall CB, Epstein LG. Cellular localization of human herpesvirus-6 in the brains of children with AIDS encephalopathy. Journal of Neurovirology. 1: 30-9. PMID 9222340 DOI: 10.3109/13550289509111008  0.368
1995 Dollard SC, James HJ, Sharer LR, Epstein LG, Gelbard HA, Dewhurst S. Activation of nuclear factor kappa B in brains from children with HIV-1 encephalitis. Neuropathology and Applied Neurobiology. 21: 518-28. PMID 8745241 DOI: 10.1111/J.1365-2990.1995.Tb01098.X  0.641
1995 Talley AK, Dewhurst S, Perry SW, Dollard SC, Gummuluru S, Fine SM, New D, Epstein LG, Gendelman HE, Gelbard HA. Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Molecular and Cellular Biology. 15: 2359-66. PMID 7739519 DOI: 10.1128/Mcb.15.5.2359  0.584
1995 Frenkel LM, Wagner LE, Atwood SM, Cummins TJ, Dewhurst S. Specific, sensitive, and rapid assay for human immunodeficiency virus type 1 pol mutations associated with resistance to zidovudine and didanosine. Journal of Clinical Microbiology. 33: 342-7. PMID 7714190 DOI: 10.1128/Jcm.33.2.342-347.1995  0.346
1995 Frenkel LM, Wagner LE, Demeter LM, Dewhurst S, Coombs RW, Murante BL, Reichman RC. Effects of zidovudine use during pregnancy on resistance and vertical transmission of human immunodeficiency virus type 1. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 20: 1321-6. PMID 7620018 DOI: 10.1093/Clinids/20.5.1321  0.358
1995 Sharer LR, Gelbard HA, Dollard SC, Epstein LG, Dewhurst S. NFKB ACTIVITY AND HIV-1 ENCEPHALITIS IN CHILDREN Journal of Neuropathology and Experimental Neurology. 54: 437. DOI: 10.1097/00005072-199505000-00120  0.595
1994 Hall CB, Long CE, Schnabel KC, Caserta MT, McIntyre KM, Costanzo MA, Knott A, Dewhurst S, Insel RA, Epstein LG. Human herpesvirus-6 infection in children. A prospective study of complications and reactivation. The New England Journal of Medicine. 331: 432-8. PMID 8035839 DOI: 10.1056/Nejm199408183310703  0.3
1994 Dollard SC, Gummuluru S, Tsang S, Fultz PN, Dewhurst S. Enhanced responsiveness to nuclear factor κB contributes to the unique phenotype of simian immunodeficiency virus variant SIV(smmPBj14) Journal of Virology. 68: 7800-7809. PMID 7966569 DOI: 10.1128/Jvi.68.12.7800-7809.1994  0.401
1993 Dewhurst S, McIntyre K, Schnabel K, Hall CB. Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants. Journal of Clinical Microbiology. 31: 416-418. PMID 8381815 DOI: 10.1128/Jcm.31.2.416-418.1993  0.303
1992 Dewhurst S, Embretson JE, Fultz PN, Mullins JI. Molecular clones from a non-acutely pathogenic derivative of SIV(smmPBj14): Characterization and comparison to acutely pathogenic clones Aids Research and Human Retroviruses. 8: 1179-1187. PMID 1503826 DOI: 10.1089/Aid.1992.8.1179  0.358
1992 Dewhurst S, Chandran B, Mcintyre K, Schnabel K, Hall CB. Phenotypic and genetic polymorphisms among human herpesvirus-6 isolates from North American infants Virology. 190: 490-493. PMID 1326815 DOI: 10.1016/0042-6822(92)91240-U  0.323
1990 Dewhurst S, Embretson JE, Anderson DC, Mullins JI, Fultz PN. Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14 Nature. 345: 636-640. PMID 1971917 DOI: 10.1038/345636A0  0.353
1988 Dewhurst S, Sakai K, Zhang XH, Wasiak A, Volsky DJ. Establishment of human glial cell lines chronically infected with the human immunodeficiency virus. Virology. 162: 151-9. PMID 3336939 DOI: 10.1016/0042-6822(88)90404-7  0.651
1988 Sakai K, Dewhurst S, Ma XY, Volsky DJ. Differences in cytopathogenicity and host cell range among infectious molecular clones of human immunodeficiency virus type 1 simultaneously isolated from an individual. Journal of Virology. 62: 4078-85. PMID 3172338 DOI: 10.1128/Jvi.62.11.4078-4085.1988  0.635
1987 Dewhurst S, Bresser J, Stevenson M, Sakai K, Evinger-Hodges MJ, Volsky DJ. Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV). Febs Letters. 213: 138-43. PMID 3549356 DOI: 10.1016/0014-5793(87)81479-5  0.643
1987 Smith DM, Dewhurst S, Shepherd S, Volsky DJ, Goldsmith JC. False-positive enzyme-linked immunosorbent assay reactions for antibody to human immunodeficiency virus in a population of midwestern patients with congenital bleeding disorders. Transfusion. 27: 112. PMID 3544370 DOI: 10.1046/J.1537-2995.1987.27187121453.X  0.545
1987 Dewhurst S, Stevenson M, Volsky DJ. Expression of the T4 molecule (AIDS virus receptor) by human brain-derived cells. Febs Letters. 213: 133-7. PMID 3493919 DOI: 10.1016/0014-5793(87)81478-3  0.62
1987 Dewhurst S, Stevenson M, McComb RD, Volsky DJ. Expression of glial fibrillary acidic protein in human glioma cell lines as detected by molecular hybridization. Acta Neuropathologica. 73: 383-6. PMID 3303810 DOI: 10.1007/Bf00688264  0.542
1987 Dewhurst S, Sakai K, Bresser J, Stevenson M, Evinger-Hodges MJ, Volsky DJ. Persistent productive infection of human glial cells by human immunodeficiency virus (HIV) and by infectious molecular clones of HIV. Journal of Virology. 61: 3774-82. PMID 2446007 DOI: 10.1128/Jvi.61.12.3774-3782.1987  0.644
1986 Goldsmith JC, Dewhurst S, Hedenskog M, Casareale D, Volsky DJ. High prevalence and high titers of LAV/HTLV-III antibodies in healthy hemophiliacs in the midwestern United States. The American Journal of Medicine. 81: 579-83. PMID 3532787 DOI: 10.1016/0002-9343(86)90540-1  0.514
1986 Volsky DJ, Wu YT, Stevenson M, Dewhurst S, Sinangil F, Merino F, Rodriguez L, Godoy G. Antibodies to HTLV-III/LAV in Venezuelan patients with acute malarial infections. The New England Journal of Medicine. 314: 647-8. PMID 3511375 DOI: 10.1056/Nejm198603063141013  0.564
1986 Hedenskog M, Dewhurst S, Ludvigsen C, Sinangil F, Rodriguez L, Wu YT, Volsky DJ. Testing for antibodies to AIDS-associated retrovirus (HTLV-III/LAV) by indirect fixed cell immunofluorescence: specificity, sensitivity, and applications. Journal of Medical Virology. 19: 325-34. PMID 3018138 DOI: 10.1002/Jmv.1890190405  0.554
1986 Volsky DJ, Rodriguez L, Dewhurst S, Sinangil F, Sakai K, Merino F, Esparza B, De Salvo L. Antibodies to acquired immune deficiency syndrome (AIDS)-associated virus (HTLV-III/LAV) in Venezuelan populations. Aids Research. 2: 79-92. PMID 3013223 DOI: 10.1089/Aid.1.1986.2.79  0.569
1986 Dewhurst S, Volsky DJ. A simple method for the production of specific antiserum to the second nuclear antigen (EBNA-2) of Epstein-Barr virus (EBV). Journal of Immunological Methods. 87: 283-7. PMID 3005420 DOI: 10.1016/0022-1759(86)90543-0  0.536
1986 Volsky DJ, Sakai K, Stevenson M, Dewhurst S. Retroviral etiology of the acquired immune deficiency syndrome (AIDS). Aids Research. 2: S35-48. PMID 2881556  0.561
1985 Rodriquez L, Dewhurst S, Sinangil F, Merino F, Godoy G, Volsky DJ. Antibodies to HTLV-III/LAV among aboriginal Amazonian Indians in Venezuela. Lancet. 2: 1098-100. PMID 2865571  0.48
1984 Casareale D, Dewhurst S, Sonnabend J, Sinangil F, Purtilo DT, Volsky DJ. Prevalence of AIDS-associated retrovirus and antibodies among male homosexuals at risk for AIDS in Greenwich Village. Aids Research. 1: 407-21. PMID 6085926 DOI: 10.1089/Aid.1.1983.1.407  0.537
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