Sanjay B. Maggirwar, MBA., Ph.D. - Publications

Microbiology and Immunology University of Rochester Medical Center, Rochester, NY, United States 
HIV-1, NFkB, Platelet biology, cell signaling, CD40

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Year Citation  Score
2020 Murray KD, Singh MV, Zhuang Y, Uddin MN, Qiu X, Weber MT, Tivarus ME, Wang HZ, Sahin B, Zhong J, Maggirwar SB, Schifitto G. Pathomechanisms of HIV-Associated Cerebral Small Vessel Disease: A Comprehensive Clinical and Neuroimaging Protocol and Analysis Pipeline. Frontiers in Neurology. 11: 595463. PMID 33384655 DOI: 10.3389/fneur.2020.595463  0.52
2020 Simpson SR, Singh MV, Dewhurst S, Schifitto G, Maggirwar SB. Platelets function as an acute viral reservoir during HIV-1 infection by harboring virus and T-cell complex formation. Blood Advances. 4: 4512-4521. PMID 32946568 DOI: 10.1182/bloodadvances.2020002420  0.88
2020 Piekna-Przybylska D, Bambara RA, Maggirwar SB, Dewhurst S. G-quadruplex ligands targeting telomeres do not inhibit HIV promoter activity and cooperate with latency reversing agents in killing latently infected cells. Cell Cycle (Georgetown, Tex.). 1-16. PMID 32807015 DOI: 10.1080/15384101.2020.1796268  0.88
2018 Singh MV, Kotla S, Le NT, Ko KA, Heo KS, Wang Y, Fujii Y, Vu HT, McBeath E, Thomas TN, Gi YJ, Tao Y, Medina JL, Taunton J, Carson N, ... ... Maggirwar S, et al. Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV Individuals: Implications for Atherogenesis. Circulation. PMID 30586719 DOI: 10.1161/CIRCULATIONAHA.118.036232  0.52
2018 Falsetta ML, Foster DC, Woeller CF, Pollock SJ, Bonham AD, Piekna-Przybylska D, Maggirwar SB, Haidaris CG, Phipps RP. Toll-Like Receptor Signaling Contributes to Proinflammatory Mediator Production in Localized Provoked Vulvodynia. Journal of Lower Genital Tract Disease. 22: 52-57. PMID 29271858 DOI: 10.1097/LGT.0000000000000364  0.48
2017 Singh VB, Singh MV, Piekna-Przybylska D, Gorantla S, Poluektova LY, Maggirwar SB. Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection. Scientific Reports. 7: 9578. PMID 28852071 DOI: 10.1038/s41598-017-10241-0  0.36
2016 Piepenbrink MS, Samuel M, Zheng B, Carter B, Fucile C, Bunce C, Kiebala M, Khan AA, Thakar J, Maggirwar SB, Morse D, Rosenberg AF, Haughey NJ, Valenti W, Keefer MC, et al. Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users. Plos One. 11: e0158641. PMID 27379802 DOI: 10.1371/journal.pone.0158641  0.88
2016 Jackson JW, Singh MV, Singh VB, Jones LD, Davidson GA, Ture S, Morrell CN, Schifitto G, Maggirwar SB. Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis. Plos One. 11: e0157115. PMID 27270236 DOI: 10.1371/journal.pone.0157115  0.88
2016 Singh VB, Singh MV, Gorantla S, Poluektova LY, Maggirwar SB. Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice. Scientific Reports. 6: 26876. PMID 27241024 DOI: 10.1038/srep26876  0.36
2016 De Jesús Andino F, Jones L, Maggirwar SB, Robert J. Frog Virus 3 dissemination in the brain of tadpoles, but not in adult Xenopus, involves blood brain barrier dysfunction. Scientific Reports. 6: 22508. PMID 26931458 DOI: 10.1038/srep22508  0.88
2015 Kiebala M, Singh MV, Piepenbrink MS, Qiu X, Kobie JJ, Maggirwar SB. Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. Plos One. 10: e0130061. PMID 26076359 DOI: 10.1371/journal.pone.0130061  0.88
2015 Lannan KL, Sahler J, Kim N, Spinelli SL, Maggirwar SB, Garraud O, Cognasse F, Blumberg N, Phipps RP. Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles. Frontiers in Immunology. 6: 48. PMID 25762994 DOI: 10.3389/fimmu.2015.00048  0.88
2015 Singh VB, Wooten AK, Jackson JW, Maggirwar SB, Kiebala M. Investigating the role of ankyrin-rich membrane spanning protein in human immunodeficiency virus type-1 Tat-induced microglia activation. Journal of Neurovirology. 21: 186-98. PMID 25636783 DOI: 10.1007/s13365-015-0318-2  0.88
2015 Kiebala M, Skalska J, Casulo C, Brookes PS, Peterson DR, Hilchey SP, Dai Y, Grant S, Maggirwar SB, Bernstein SH. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach. Experimental Hematology. 43: 89-99. PMID 25448488 DOI: 10.1016/j.exphem.2014.10.004  0.88
2014 Singh MV, Davidson DC, Jackson JW, Singh VB, Silva J, Ramirez SH, Maggirwar SB. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). 192: 4674-84. PMID 24729609 DOI: 10.4049/jimmunol.1302318  0.88
2013 Davidson DC, Jackson JW, Maggirwar SB. Targeting platelet-derived soluble CD40 ligand: a new treatment strategy for HIV-associated neuroinflammation? Journal of Neuroinflammation. 10: 144. PMID 24289660 DOI: 10.1186/1742-2094-10-144  0.88
2013 Ma Q, Gelbard HA, Maggirwar SB, Dewhurst S, Gendelman HE, Peterson DR, DiFrancesco R, Hochreiter JS, Morse GD, Schifitto G. Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients. Journal of Neurovirology. 19: 254-60. PMID 23737347 DOI: 10.1007/s13365-013-0172-z  0.88
2013 McMillan DH, Woeller CF, Thatcher TH, Spinelli SL, Maggirwar SB, Sime PJ, Phipps RP. Attenuation of inflammatory mediator production by the NF-κB member RelB is mediated by microRNA-146a in lung fibroblasts. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L774-81. PMID 23564509 DOI: 10.1152/ajplung.00352.2012  0.88
2013 Davidson DC, Schifitto G, Maggirwar SB. Valproic acid inhibits the release of soluble CD40L induced by non-nucleoside reverse transcriptase inhibitors in human immunodeficiency virus infected individuals. Plos One. 8: e59950. PMID 23555843 DOI: 10.1371/journal.pone.0059950  0.88
2012 Davidson DC, Hirschman MP, Sun A, Singh MV, Kasischke K, Maggirwar SB. Excess soluble CD40L contributes to blood brain barrier permeability in vivo: implications for HIV-associated neurocognitive disorders. Plos One. 7: e51793. PMID 23251626 DOI: 10.1371/journal.pone.0051793  0.88
2012 Singh MV, Davidson DC, Kiebala M, Maggirwar SB. Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1. Journal of Virological Methods. 181: 170-6. PMID 22387340 DOI: 10.1016/j.jviromet.2012.02.005  0.88
2011 Xu X, Steere RR, Fedorchuk CA, Pang J, Lee JY, Lim JH, Xu H, Pan ZK, Maggirwar SB, Li JD. Activation of epidermal growth factor receptor is required for NTHi-induced NF-κB-dependent inflammation. Plos One. 6: e28216. PMID 22132240 DOI: 10.1371/journal.pone.0028216  0.88
2011 Morrell CN, Maggirwar SB. Recently recognized platelet agonists. Current Opinion in Hematology. 18: 309-14. PMID 21730836 DOI: 10.1097/MOH.0b013e3283497dfb  0.88
2011 McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP. Lung-targeted overexpression of the NF-κB member RelB inhibits cigarette smoke-induced inflammation. The American Journal of Pathology. 179: 125-33. PMID 21703398 DOI: 10.1016/j.ajpath.2011.03.030  0.88
2011 Cao S, Wu C, Yang Y, Sniderhan LF, Maggirwar SB, Dewhurst S, Lu Y. Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS. Journal of Neuroinflammation. 8: 48. PMID 21569583 DOI: 10.1186/1742-2094-8-48  0.88
2011 Kiebala M, Maggirwar SB. Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency virus-1 Tat-mediated activation of microglial cells. Plos One. 6: e18633. PMID 21494611 DOI: 10.1371/journal.pone.0018633  0.88
2011 Kulkarni AA, Thatcher TH, Olsen KC, Maggirwar SB, Phipps RP, Sime PJ. PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis. Plos One. 6: e15909. PMID 21253589 DOI: 10.1371/journal.pone.0015909  0.88
2011 Davidson DC, Hirschman MP, Spinelli SL, Morrell CN, Schifitto G, Phipps RP, Maggirwar SB. Antiplatelet activity of valproic acid contributes to decreased soluble CD40 ligand production in HIV type 1-infected individuals. Journal of Immunology (Baltimore, Md. : 1950). 186: 584-91. PMID 21115729 DOI: 10.4049/jimmunol.1001911  0.88
2010 Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD, Dewhurst S. Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure. Hearing Research. 270: 21-7. PMID 20971179 DOI: 10.1016/j.heares.2010.10.008  0.88
2010 Perry SW, Barbieri J, Tong N, Polesskaya O, Pudasaini S, Stout A, Lu R, Kiebala M, Maggirwar SB, Gelbard HA. Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14153-64. PMID 20962236 DOI: 10.1523/JNEUROSCI.1042-10.2010  0.88
2010 Spinelli SL, Maggirwar SB, Blumberg N, Phipps RP. Nuclear emancipation: a platelet tour de force. Science Signaling. 3: pe37. PMID 20959522 DOI: 10.1126/scisignal.3144pe37  0.88
2010 Gelbard HA, Dewhurst S, Maggirwar SB, Kiebala M, Polesskaya O, Gendelman HE. Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 392-8. PMID 20880503 DOI: 10.1016/j.nurt.2010.08.001  0.88
2010 Kiebala M, Polesskaya O, Yao Z, Perry SW, Maggirwar SB. Nuclear factor-kappa B family member RelB inhibits human immunodeficiency virus-1 Tat-induced tumor necrosis factor-alpha production. Plos One. 5: e11875. PMID 20686703 DOI: 10.1371/journal.pone.0011875  0.68
2010 Ramirez SH, Fan S, Dykstra H, Reichenbach N, Del Valle L, Potula R, Phipps RP, Maggirwar SB, Persidsky Y. Dyad of CD40/CD40 ligand fosters neuroinflammation at the blood-brain barrier and is regulated via JNK signaling: implications for HIV-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9454-64. PMID 20631174 DOI: 10.1523/JNEUROSCI.5796-09.2010  0.88
2010 Desmet EA, Hollenbaugh JA, Sime PJ, Wright TW, Topham DJ, Sant AJ, Takimoto T, Dewhurst S, Maggirwar SB. Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells. Virology. 400: 224-32. PMID 20185156 DOI: 10.1016/j.virol.2010.02.001  0.88
2010 Spinelli SL, Casey AE, Pollock SJ, Gertz JM, McMillan DH, Narasipura SD, Mody NA, King MR, Maggirwar SB, Francis CW, Taubman MB, Blumberg N, Phipps RP. Platelets and megakaryocytes contain functional nuclear factor-kappaB. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 591-8. PMID 20042710 DOI: 10.1161/ATVBAHA.109.197343  0.88
2010 Eggert D, Dash PK, Gorantla S, Dou H, Schifitto G, Maggirwar SB, Dewhurst S, Poluektova L, Gelbard HA, Gendelman HE. Neuroprotective activities of CEP-1347 in models of neuroAIDS. Journal of Immunology (Baltimore, Md. : 1950). 184: 746-56. PMID 19966207 DOI: 10.4049/jimmunol.0902962  0.88
2009 Skalska J, Brookes PS, Nadtochiy SM, Hilchey SP, Jordan CT, Guzman ML, Maggirwar SB, Briehl MM, Bernstein SH. Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide. Plos One. 4: e8115. PMID 19956548 DOI: 10.1371/journal.pone.0008115  0.88
2009 Sniderhan LF, Garcia-Bates TM, Burgart M, Bernstein SH, Phipps RP, Maggirwar SB. Neurotrophin signaling through tropomyosin receptor kinases contributes to survival and proliferation of non-Hodgkin lymphoma. Experimental Hematology. 37: 1295-309. PMID 19716854 DOI: 10.1016/j.exphem.2009.08.005  0.88
2009 Schifitto G, Zhong J, Gill D, Peterson DR, Gaugh MD, Zhu T, Tivarus M, Cruttenden K, Maggirwar SB, Gendelman HE, Dewhurst S, Gelbard HA. Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment. Journal of Neurovirology. 15: 176-86. PMID 19306230 DOI: 10.1080/13550280902758973  0.88
2009 Garcia-Bates TM, Peslak SA, Baglole CJ, Maggirwar SB, Bernstein SH, Phipps RP. Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and survival. Cancer Immunology, Immunotherapy : Cii. 58: 1071-83. PMID 19018532 DOI: 10.1007/s00262-008-0625-z  0.88
2008 Norman JP, Perry SW, Reynolds HM, Kiebala M, De Mesy Bentley KL, Trejo M, Volsky DJ, Maggirwar SB, Dewhurst S, Masliah E, Gelbard HA. HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization. Plos One. 3: e3731. PMID 19009018 DOI: 10.1371/journal.pone.0003731  0.88
2008 Baglole CJ, Maggirwar SB, Gasiewicz TA, Thatcher TH, Phipps RP, Sime PJ. The aryl hydrocarbon receptor attenuates tobacco smoke-induced cyclooxygenase-2 and prostaglandin production in lung fibroblasts through regulation of the NF-kappaB family member RelB. The Journal of Biological Chemistry. 283: 28944-57. PMID 18697742 DOI: 10.1074/jbc.M800685200  0.88
2008 Sniderhan LF, Stout A, Lu Y, Chao MV, Maggirwar SB. Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling. Molecular and Cellular Neurosciences. 38: 404-16. PMID 18501627 DOI: 10.1016/j.mcn.2008.04.001  0.88
2008 Yang SR, Valvo S, Yao H, Kode A, Rajendrasozhan S, Edirisinghe I, Caito S, Adenuga D, Henry R, Fromm G, Maggirwar S, Li JD, Bulger M, Rahman I. IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung. American Journal of Respiratory Cell and Molecular Biology. 38: 689-98. PMID 18239189 DOI: 10.1165/rcmb.2007-0379OC  0.88
2008 Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy. Retrovirology. 5: 11. PMID 18237430 DOI: 10.1186/1742-4690-5-11  0.88
2007 Dewhurst S, Maggirwar SB, Schifitto G, Gendelman HE, Gelbard HA. Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 93-6. PMID 18040831 DOI: 10.1007/s11481-006-9051-1  0.88
2007 Pingle SC, Jajoo S, Mukherjea D, Sniderhan LF, Jhaveri KA, Marcuzzi A, Rybak LP, Maggirwar SB, Ramkumar V. Activation of the adenosine A1 receptor inhibits HIV-1 tat-induced apoptosis by reducing nuclear factor-kappaB activation and inducible nitric-oxide synthase. Molecular Pharmacology. 72: 856-67. PMID 17609415 DOI: 10.1124/mol.106.031427  0.88
2007 Goyos A, Guselnikov S, Chida AS, Sniderhan LF, Maggirwar SB, Nedelkovska H, Robert J. Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses. European Journal of Immunology. 37: 1494-501. PMID 17492621 DOI: 10.1002/eji.200636570  0.88
2007 Thatcher TH, Maggirwar SB, Baglole CJ, Lakatos HF, Gasiewicz TA, Phipps RP, Sime PJ. Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB. The American Journal of Pathology. 170: 855-64. PMID 17322371 DOI: 10.2353/ajpath.2007.060391  0.88
2007 Sui Z, Sniderhan LF, Schifitto G, Phipps RP, Gelbard HA, Dewhurst S, Maggirwar SB. Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia. Journal of Immunology (Baltimore, Md. : 1950). 178: 3226-36. PMID 17312171  0.88
2007 Wang J, Gigliotti F, Bhagwat SP, Maggirwar SB, Wright TW. Pneumocystis stimulates MCP-1 production by alveolar epithelial cells through a JNK-dependent mechanism. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1495-505. PMID 17307812 DOI: 10.1152/ajplung.00452.2006  0.88
2007 Chugh P, Fan S, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line. Journal of Molecular Biology. 366: 67-81. PMID 17157319 DOI: 10.1016/j.jmb.2006.11.011  0.88
2006 Cheng T, Petraglia AL, Li Z, Thiyagarajan M, Zhong Z, Wu Z, Liu D, Maggirwar SB, Deane R, Fernández JA, LaRue B, Griffin JH, Chopp M, Zlokovic BV. Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage. Nature Medicine. 12: 1278-85. PMID 17072311 DOI: 10.1038/nm1498  0.88
2006 Ray DM, Morse KM, Hilchey SP, Garcia TM, Felgar RE, Maggirwar SB, Phipps RP, Bernstein SH. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway. Experimental Hematology. 34: 1202-11. PMID 16939813 DOI: 10.1016/j.exphem.2006.04.026  0.88
2006 Sui Z, Sniderhan LF, Fan S, Kazmierczak K, Reisinger E, Kovács AD, Potash MJ, Dewhurst S, Gelbard HA, Maggirwar SB. Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons. The European Journal of Neuroscience. 23: 2623-34. PMID 16817865 DOI: 10.1111/j.1460-9568.2006.04813.x  0.88
2006 Sui Z, Fan S, Sniderhan L, Reisinger E, Litzburg A, Schifitto G, Gelbard HA, Dewhurst S, Maggirwar SB. Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation. Journal of Immunology (Baltimore, Md. : 1950). 177: 702-11. PMID 16785569  0.88
2006 Sui Z, Kovács AD, Maggirwar SB. Recruitment of active glycogen synthase kinase-3 into neuronal lipid rafts. Biochemical and Biophysical Research Communications. 345: 1643-8. PMID 16735023 DOI: 10.1016/j.bbrc.2006.05.087  0.88
2006 Yang SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggirwar SB, Kilty I, Rahman I. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L46-57. PMID 16473865 DOI: 10.1152/ajplung.00241.2005  0.88
2006 Zeng L, Planelles V, Sui Z, Gartner S, Maggirwar SB, Dewhurst S, Ye L, Nerurkar VR, Yanagihara R, Lu Y. HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1. The Journal of Gene Medicine. 8: 18-28. PMID 16142830 DOI: 10.1002/jgm.825  0.88
2005 Dou H, Ellison B, Bradley J, Kasiyanov A, Poluektova LY, Xiong H, Maggirwar S, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8375-85. PMID 16162919 DOI: 10.1523/JNEUROSCI.2164-05.2005  0.88
2005 Wang J, Gigliotti F, Maggirwar S, Johnston C, Finkelstein JN, Wright TW. Pneumocystis carinii activates the NF-κB signaling pathway in alveolar epithelial cells Infection and Immunity. 73: 2766-2777. PMID 15845480 DOI: 10.1128/IAI.73.5.2766-2777.2005  0.88
2005 Jin N, Kovács AD, Sui Z, Dewhurst S, Maggirwar SB. Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death. Neuropharmacology. 48: 576-83. PMID 15755485 DOI: 10.1016/j.neuropharm.2004.11.010  0.88
2004 Kovács AD, Chakraborty-Sett S, Ramirez SH, Sniderhan LF, Williamson AL, Maggirwar SB. Mechanism of NF-kappaB inactivation induced by survival signal withdrawal in cerebellar granule neurons. The European Journal of Neuroscience. 20: 345-52. PMID 15233744 DOI: 10.1111/j.1460-9568.2004.03493.x  0.88
2004 Ramirez SH, Fan S, Maguire CA, Perry S, Hardiek K, Ramkumar V, Gelbard HA, Dewhurst S, Maggirwar SB. Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal. Journal of Neuroscience Research. 77: 258-69. PMID 15211592 DOI: 10.1002/jnr.20150  0.88
2003 Dou H, Birusingh K, Faraci J, Gorantla S, Poluektova LY, Maggirwar SB, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9162-70. PMID 14534250  0.88
2003 Sanchez JF, Sniderhan LF, Williamson AL, Fan S, Chakraborty-Sett S, Maggirwar SB. Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling. Molecular and Cellular Biology. 23: 4649-62. PMID 12808104 DOI: 10.1128/MCB.23.13.4649-4662.2003  0.88
2003 Pingle SC, Sanchez JF, Hallam DM, Williamson AL, Maggirwar SB, Ramkumar V. Hypertonicity inhibits lipopolysaccharide-induced nitric oxide synthase expression in smooth muscle cells by inhibiting nuclear factor kappaB. Molecular Pharmacology. 63: 1238-47. PMID 12761333 DOI: 10.1124/mol.63.6.1238  0.88
2001 Ramirez SH, Sanchez JF, Dimitri CA, Gelbard HA, Dewhurst S, Maggirwar SB. Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. Journal of Neurochemistry. 78: 874-89. PMID 11520908 DOI: 10.1046/j.1471-4159.2001.00467.x  0.88
2001 Tong N, Sanchez JF, Maggirwar SB, Ramirez SH, Guo H, Dewhurst S, Gelbard HA. Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. The European Journal of Neuroscience. 13: 1913-22. PMID 11403684 DOI: 10.1046/j.0953-816X.2001.01572.x  0.88
2000 Maggirwar SB, Ramirez S, Tong N, Gelbard HA, Dewhurst S. Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells. Journal of Neurochemistry. 74: 527-39. PMID 10646503 DOI: 10.1046/j.1471-4159.2000.740527.x  0.88
1999 Maggirwar SB, Tong N, Ramirez S, Gelbard HA, Dewhurst S. HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity. Journal of Neurochemistry. 73: 578-86. PMID 10428053 DOI: 10.1046/j.1471-4159.1999.0730578.x  0.88
1999 Fine SM, Maggirwar SB, Elliott PR, Epstein LG, Gelbard HA, Dewhurst S. Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia. Journal of Neuroimmunology. 95: 55-64. PMID 10229115 DOI: 10.1016/S0165-5728(98)00267-7  0.88
1999 Sun SC, Maggirwar SB, Harhaj EW, Uhlik M. Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells. Oncogene. 18: 1401-9. PMID 10050877 DOI: 10.1038/sj.onc.1202430  0.88
1998 Maggirwar SB, Sarmiere PD, Dewhurst S, Freeman RS. Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10356-65. PMID 9852573  0.88
1998 New DR, Maggirwar SB, Epstein LG, Dewhurst S, Gelbard HA. HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism. The Journal of Biological Chemistry. 273: 17852-8. PMID 9651389 DOI: 10.1074/jbc.273.28.17852  0.88
1997 Maggirwar SB, Harhaj EW, Sun SC. Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors. Molecular and Cellular Biology. 17: 2605-14. PMID 9111330  0.88
1997 Ford MS, Maggirwar SB, Rybak LP, Whitworth C, Ramkumar V. Expression and function of adenosine receptors in the chinchilla cochlea. Hearing Research. 105: 130-40. PMID 9083810 DOI: 10.1016/S0378-5955(96)00204-3  0.88
1997 Good L, Maggirwar SB, Harhaj EW, Sun SC. Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells. The Journal of Biological Chemistry. 272: 1425-8. PMID 8999806 DOI: 10.1074/jbc.272.3.1425  0.88
1997 Harhaj EW, Maggirwar SB, Sun SC. Regulation of the interleukin-2 CD28 responsive element by NF-ATp and NF-κB/Rel Faseb Journal. 11: A1201.  0.88
1996 Harhaj EW, Maggirwar SB, Good L, Sun SC. CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers. Molecular and Cellular Biology. 16: 6736-43. PMID 8943328  0.88
1996 Mandal M, Maggirwar SB, Sharma N, Kaufmann SH, Sun SC, Kumar R. Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly(ADP-ribose) polymerase and restores the NF-kappaB signaling pathway. The Journal of Biological Chemistry. 271: 30354-9. PMID 8939996 DOI: 10.1074/jbc.271.48.30354  0.88
1996 Good L, Maggirwar SB, Sun SC. Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element. The Embo Journal. 15: 3744-50. PMID 8670878  0.88
1996 Good LF, Maggirwar SB, Kealiher A, Uhlik M, Sun SC. Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors. Biochemical and Biophysical Research Communications. 223: 123-8. PMID 8660357 DOI: 10.1006/bbrc.1996.0856  0.88
1996 Harhaj EW, Maggirwar SB, Sun SC. Inhibition of p105 processing by NF-kappaB proteins in transiently transfected cells. Oncogene. 12: 2385-92. PMID 8649779  0.88
1995 Maggirwar SB, Harhaj E, Sun SC. Activation of NF-kappa B/Rel by Tax involves degradation of I kappa B alpha and is blocked by a proteasome inhibitor. Oncogene. 11: 993-8. PMID 7675460  0.88
1995 Sun SC, Maggirwar SB, Harhaj E. Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites. The Journal of Biological Chemistry. 270: 18347-51. PMID 7629157 DOI: 10.1074/jbc.270.31.18347  0.88
1995 Ramkumar V, Nie Z, Rybak LP, Maggirwar SB. Adenosine, antioxidant enzymes and cytoprotection. Trends in Pharmacological Sciences. 16: 283-5. PMID 7482990 DOI: 10.1016/S0165-6147(00)89051-3  0.88
1994 Maggirwar SB, Dhanraj DN, Somani SM, Ramkumar V. Adenosine acts as an endogenous activator of the cellular antioxidant defense system. Biochemical and Biophysical Research Communications. 201: 508-15. PMID 8002980 DOI: 10.1006/bbrc.1994.1731  0.88
1992 Ramesh G, Deshpande MS, Maggirwar SB, Hegde MV, Rale VB. α-Glucosidase synthesis in batch and continuous culture ofSaccharomyces cerevisiae. World Journal of Microbiology & Biotechnology. 8: 42-4. PMID 24425332 DOI: 10.1007/BF01200682  0.88
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