Douglas H. Smith - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 

188 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Alisafaei F, Gong Z, Johnson VE, Dollé JP, Smith DH, Shenoy VB. Mechanisms of Local Stress Amplification in Axons near the Gray-White Matter Interface. Biophysical Journal. 119: 1290-1300. PMID 33027609 DOI: 10.1016/j.bpj.2020.08.024  0.52
2020 Mayer AR, Dodd AB, Ling JM, Stephenson DD, Rannou-Latella JG, Vermillion MS, Mehos CJ, Johnson VE, Gigliotti AP, Dodd RJ, Chaudry IH, Meier TB, Smith DH, Bragin DE, Lai C, et al. Survival Rates and Biomarkers in A Large Animal Model of Traumatic Brain Injury Combined with Two Different Levels of Blood Loss. Shock (Augusta, Ga.). PMID 32881755 DOI: 10.1097/SHK.0000000000001653  0.52
2020 Smith DH, Stewart W. 'Concussion' is not a true diagnosis. Nature Reviews. Neurology. PMID 32647140 DOI: 10.1038/s41582-020-0382-y  0.52
2020 Katiyar KS, Struzyna LA, Morand JP, Burrell JC, Clements B, Laimo FA, Browne KD, Kohn J, Ali Z, Ledebur HC, Smith DH, Cullen DK. Tissue Engineered Axon Tracts Serve as Living Scaffolds to Accelerate Axonal Regeneration and Functional Recovery Following Peripheral Nerve Injury in Rats. Frontiers in Bioengineering and Biotechnology. 8: 492. PMID 32523945 DOI: 10.3389/fbioe.2020.00492  0.96
2020 Arena JD, Smith DH, Lee EB, Gibbons GS, Irwin DJ, Robinson JL, Lee VM, Trojanowski JQ, Stewart W, Johnson VE. Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease. Brain : a Journal of Neurology. PMID 32390044 DOI: 10.1093/brain/awaa071  0.72
2020 Siman R, Cui H, Wewerka SS, Hamel L, Smith DH, Zwank MD. Serum SNTF, a Surrogate Marker of Axonal Injury, Is Prognostic for Lasting Brain Dysfunction in Mild TBI Treated in the Emergency Department. Frontiers in Neurology. 11: 249. PMID 32322237 DOI: 10.3389/fneur.2020.00249  0.52
2020 Smith DH, Stewart W. Genetic interplay with soccer ball heading. Nature Reviews. Neurology. PMID 32152459 DOI: 10.1038/s41582-020-0334-6  0.52
2019 Xu ZX, Albayar A, Dollé JP, Hansel G, Bianchini J, Sullivan PZ, Kacy Cullen D, Smith DH, Ozturk AK. Dorsal root ganglion axons facilitate and guide cortical neural outgrowth: In vitro modeling of spinal cord injury axonal regeneration. Restorative Neurology and Neuroscience. PMID 31594262 DOI: 10.3233/RNN-190933  0.88
2019 Verma R, Swanson RL, Parker D, Ould Ismail AA, Shinohara RT, Alappatt JA, Doshi J, Davatzikos C, Gallaway M, Duda D, Chen HI, Kim JJ, Gur RC, Wolf RL, Grady MS, ... ... Smith DH, et al. Neuroimaging Findings in US Government Personnel With Possible Exposure to Directional Phenomena in Havana, Cuba. Jama. 322: 336-347. PMID 31334794 DOI: 10.1001/jama.2019.9269  0.64
2019 Lee EB, Kinch K, Johnson VE, Trojanowski JQ, Smith DH, Stewart W. Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players. Acta Neuropathologica. PMID 31152201 DOI: 10.1007/s00401-019-02030-y  0.72
2019 Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, ... ... Smith DH, et al. Primum non nocere: a call for balance when reporting on CTE. The Lancet. Neurology. 18: 231-233. PMID 30784550 DOI: 10.1016/S1474-4422(19)30020-1  0.72
2019 Smith DH, Johnson VE, Trojanowski JQ, Stewart W. Chronic traumatic encephalopathy - confusion and controversies. Nature Reviews. Neurology. PMID 30664683 DOI: 10.1038/s41582-018-0114-8  0.72
2019 Chen HI, Jgamadze D, Lim J, Mensah-Brown K, Wolf JA, Mills JA, Smith D. Functional cortical axon tracts generated from human stem cell-derived neurons. Tissue Engineering. Part A. PMID 30648482 DOI: 10.1089/ten.TEA.2018.0270  0.88
2018 Ulyanova AV, Koch PF, Cottone C, Grovola MR, Adam CD, Browne KD, Weber MT, Russo RJ, Gagnon KG, Smith DH, Isaac Chen H, Johnson VE, Kacy Cullen D, Wolf JA. Electrophysiological Signature Reveals Laminar Structure of the Porcine Hippocampus. Eneuro. 5. PMID 30229132 DOI: 10.1523/ENEURO.0102-18.2018  0.88
2018 Smith DH, Stewart W. Traumatic brain injury: a platform for studies in Aβ processing: Commentary on: "Rapid Aβ oligomer and protofibril accumulation in traumatic brain injury". Brain Pathology (Zurich, Switzerland). 28: 463-465. PMID 30133864 DOI: 10.1111/bpa.12534  0.52
2018 Suto Y, Nagata K, Ahmed S, Jacovides C, Browne KD, Cognetti J, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL. CEREBRAL EDEMA AND NEUROLOGICAL RECOVERY AFTER TRAUMATIC BRAIN INJURY IS WORSENED IF ACCOMPANIED BY A CONCOMITANT LONG BONE FRACTURE. Journal of Neurotrauma. PMID 30084745 DOI: 10.1089/neu.2018.5812  0.52
2018 Kovacs GG, Xie SX, Robinson JL, Lee EB, Smith DH, Schuck T, Lee VM, Trojanowski JQ. Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain. Acta Neuropathologica Communications. 6: 50. PMID 29891013 DOI: 10.1186/s40478-018-0552-y  0.72
2018 Dollé JP, Rodgers JM, Browne KD, Troxler T, Gai F, Smith DH. Newfound effect of N-acetylaspartate in preventing and reversing aggregation of amyloid-beta in vitro. Neurobiology of Disease. PMID 29859874 DOI: 10.1016/j.nbd.2018.05.023  0.48
2018 Suto Y, Nagata K, Ahmed SM, Jacovides C, Browne KD, Cognetti J, Weber MT, Johnson VE, Leone R, Kaplan LJ, Smith DH, Pascual JL. A CONCOMITANT BONE FRACTURE DELAYS COGNITIVE RECOVERY FROM TRAUMATIC BRAIN INJURY. The Journal of Trauma and Acute Care Surgery. PMID 29787539 DOI: 10.1097/TA.0000000000001957  0.52
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, ... ... Smith DH, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/neu.2018.5778  0.92
2018 Johnson VE, Weber MT, Xiao R, Cullen DK, Meaney DF, Stewart W, Smith DH. Mechanical disruption of the blood-brain barrier following experimental concussion. Acta Neuropathologica. PMID 29460006 DOI: 10.1007/s00401-018-1824-0  0.96
2018 Nagata K, Suto Y, Cognetti J, Browne KD, Kumasaka K, Johnson VE, Kaplan L, Marks J, Smith DH, Pascual JL. Early Non-anticoagulant Desulfated Heparin After TBI: Reduced Brain Edema and Leukocyte Mobilization is Associated with Improved Watermaze Learning Ability Weeks After Injury. The Journal of Trauma and Acute Care Surgery. PMID 29373460 DOI: 10.1097/TA.0000000000001819  0.52
2017 Johnson VE, Stewart W, Arena JD, Smith DH. Traumatic Brain Injury as a Trigger of Neurodegeneration. Advances in Neurobiology. 15: 383-400. PMID 28674990 DOI: 10.1007/978-3-319-57193-5_15  0.52
2017 Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, et al. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). Journal of Neuropathology and Experimental Neurology. PMID 28591867 DOI: 10.1093/jnen/nlx041  0.72
2017 Nagata K, Browne KD, Suto Y, Kumasaka K, Cognetti J, Johnson VE, Marks J, Smith DH, Pascual JL. Early Heparin Administration After TBI: Prolonged Cognitive Recovery Associated With Reduced Cerebral Edema and Neutrophil Sequestration. The Journal of Trauma and Acute Care Surgery. PMID 28538627 DOI: 10.1097/TA.0000000000001590  0.52
2017 Wolf JA, Johnson BN, Johnson VE, Putt ME, Browne KD, Mietus CJ, Brown DP, Wofford KL, Smith DH, Grady MS, Cohen AS, Cullen DK. Concussion Induces Hippocampal Circuitry Disruption in Swine. Journal of Neurotrauma. PMID 28298170 DOI: 10.1089/neu.2016.4848  0.96
2017 Chen HI, Wolf J, Smith D. Multichannel activity propagation across an engineered axon network. Journal of Neural Engineering. PMID 28140365 DOI: 10.1088/1741-2552/aa5ccd  0.64
2016 Cullen DK, Harris JP, Browne KD, Wolf JA, Duda JE, Meaney DF, Margulies SS, Smith DH. A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration. Methods in Molecular Biology (Clifton, N.J.). 1462: 289-324. PMID 27604725 DOI: 10.1007/978-1-4939-3816-2_17  0.96
2016 Nagata K, Kumasaka K, Browne KD, Li S, St-Pierre J, Cognetti J, Marks J, Johnson VE, Smith DH, Pascual JL. Unfractionated heparin after TBI reduces in vivo cerebrovascular inflammation, brain edema and accelerates cognitive recovery. The Journal of Trauma and Acute Care Surgery. PMID 27533909 DOI: 10.1097/TA.0000000000001215  0.52
2016 Smith DH, Stewart W. Tackling concussion, beyond Hollywood. The Lancet. Neurology. 15: 662-3. PMID 27302233 DOI: 10.1016/S1474-4422(16)30037-0  0.52
2016 Stewart W, Smith DH. Time to be blunt about blast traumatic brain injury. The Lancet. Neurology. PMID 27291519 DOI: 10.1016/S1474-4422(16)30058-8  0.52
2016 Chen HI, Jgamadze D, Serruya MD, Cullen DK, Wolf JA, Smith DH. Neural Substrate Expansion for the Restoration of Brain Function. Frontiers in Systems Neuroscience. 10: 1. PMID 26834579 DOI: 10.3389/fnsys.2016.00001  0.96
2016 Hay J, Johnson VE, Smith DH, Stewart W. Chronic Traumatic Encephalopathy: The Neuropathological Legacy of Traumatic Brain Injury. Annual Review of Pathology. PMID 26772317 DOI: 10.1146/annurev-pathol-012615-044116  0.52
2015 Ali ZS, Johnson VE, Stewart W, Zager EL, Xiao R, Heuer GG, Weber MT, Mallela AN, Smith DH. Neuropathological Characteristics of Brachial Plexus Avulsion Injury With and Without Concomitant Spinal Cord Injury. Journal of Neuropathology and Experimental Neurology. PMID 26671984 DOI: 10.1093/jnen/nlv002  1
2015 Li S, Eisenstadt R, Kumasaka K, Johnson VE, Marks J, Nagata K, Browne KD, Smith DH, Pascual JL. Does enoxaparin interfere with HMGB1 signalling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery. The Journal of Trauma and Acute Care Surgery. PMID 26670109 DOI: 10.1097/TA.0000000000000935  0.52
2015 Ahmadzadeh H, Smith DH, Shenoy VB. Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury. Biophysical Journal. 109: 2328-2337. PMID 26636944 DOI: 10.1016/j.bpj.2015.09.010  0.64
2015 Johnson VE, Stewart W, Weber MT, Cullen DK, Siman R, Smith DH. SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury. Acta Neuropathologica. PMID 26589592 DOI: 10.1007/s00401-015-1506-0  0.64
2015 Hay JR, Johnson VE, Young AM, Smith DH, Stewart W. Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans. Journal of Neuropathology and Experimental Neurology. 74: 1147-1157. PMID 26574669 DOI: 10.1097/NEN.0000000000000261  0.64
2015 Struzyna LA, Wolf JA, Mietus CJ, Adewole DO, Chen HI, Smith D, Cullen DK. Rebuilding brain circuitry with living micro-tissue engineered neural networks. Tissue Engineering. Part A. PMID 26414439 DOI: 10.1089/ten.TEA.2014.0557  0.64
2015 Li S, Marks JA, Eisenstadt R, Kumasaka K, Samadi D, Johnson VE, Holena DN, Allen SR, Browne KD, Smith DH, Pascual JL. Enoxaparin ameliorates post-traumatic brain injury edema and neurologic recovery, reducing cerebral leukocyte endothelial interactions and vessel permeability in vivo. The Journal of Trauma and Acute Care Surgery. 79: 78-84. PMID 26091318 DOI: 10.1097/TA.0000000000000697  0.64
2015 Smith DH, Hicks M, Johnson VE, Bergstrom D, Cummings D, Noble-Haeusslein L, Hovda D, Whalen M, Ahlers S, LaPlaca M, Tortella F, Duhaime AC, Dixon CE. Preclinical Traumatic Brain Injury Common Data Elements: Towards a Common Language Across Laboratories. Journal of Neurotrauma. PMID 26058402 DOI: 10.1089/neu.2014.3861  1
2015 Johnson VE, Meaney DF, Cullen DK, Smith DH. Animal models of traumatic brain injury. Handbook of Clinical Neurology. 127: 115-28. PMID 25702213 DOI: 10.1016/B978-0-444-52892-6.00008-8  1
2015 Meaney DF, Smith DH. Cellular biomechanics of central nervous system injury. Handbook of Clinical Neurology. 127: 105-14. PMID 25702212 DOI: 10.1016/B978-0-444-52892-6.00007-6  0.64
2015 Siman R, Shahim P, Tegner Y, Blennow K, Zetterberg H, Smith DH. Serum SNTF Increases in Concussed Professional Ice Hockey Players and Relates to the Severity of Postconcussion Symptoms. Journal of Neurotrauma. PMID 25419578 DOI: 10.1089/neu.2014.3698  0.64
2014 Kumasaka K, Marks JA, Eisenstadt R, Murcy MA, Samadi D, Li S, Johnson V, Browne KD, Smith DH, Schwab CW, Pascual JL. In vivo leukocyte-mediated brain microcirculatory inflammation: a comparison of osmotherapies and progesterone in severe traumatic brain injury. American Journal of Surgery. 208: 961-8; discussion 96. PMID 25305798 DOI: 10.1016/j.amjsurg.2014.08.004  0.64
2014 Mok TS, Geater SL, Iannotti N, Thongprasert S, Spira A, Smith D, Lee V, Lim WT, Reyderman L, Wang B, Gopalakrishna P, Garzon F, Xu L, Reynolds C. Randomized phase II study of two intercalated combinations of eribulin mesylate and erlotinib in patients with previously treated advanced non-small-cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 25: 1578-84. PMID 24827127 DOI: 10.1093/annonc/mdu174  1
2014 Ahmadzadeh H, Smith DH, Shenoy VB. Viscoelasticity of tau proteins leads to strain rate-dependent breaking of microtubules during axonal stretch injury: predictions from a mathematical model. Biophysical Journal. 106: 1123-33. PMID 24606936 DOI: 10.1016/j.bpj.2014.01.024  0.64
2014 Chen HI, Attiah M, Baltuch G, Smith DH, Hamilton RH, Lucas TH. Harnessing plasticity for the treatment of neurosurgical disorders: an overview. World Neurosurgery. 82: 648-59. PMID 24518888 DOI: 10.1016/j.wneu.2014.02.003  0.64
2014 McCauley SR, Wilde EA, Barnes A, Hanten G, Hunter JV, Levin HS, Smith DH. Patterns of early emotional and neuropsychological sequelae after mild traumatic brain injury. Journal of Neurotrauma. 31: 914-25. PMID 24344952 DOI: 10.1089/neu.2012.2826  0.64
2013 Mather JP, Roberts PE, Pan Z, Chen F, Hooley J, Young P, Xu X, Smith DH, Easton A, Li P, Bonvini E, Koenig S, Moore PA. Isolation of cancer stem like cells from human adenosquamous carcinoma of the lung supports a monoclonal origin from a multipotential tissue stem cell. Plos One. 8: e79456. PMID 24324581 DOI: 10.1371/journal.pone.0079456  1
2013 Siman R, Giovannone N, Hanten G, Wilde EA, McCauley SR, Hunter JV, Li X, Levin HS, Smith DH. Evidence That the Blood Biomarker SNTF Predicts Brain Imaging Changes and Persistent Cognitive Dysfunction in Mild TBI Patients. Frontiers in Neurology. 4: 190. PMID 24302918 DOI: 10.3389/fneur.2013.00190  0.64
2013 Pascual JL, Murcy MA, Li S, Gong W, Eisenstadt R, Kumasaka K, Sims C, Smith DH, Browne K, Allen S, Baren J. Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier. American Journal of Surgery. 206: 840-5; discussion 84. PMID 24112683 DOI: 10.1016/j.amjsurg.2013.07.016  0.64
2013 Smith DH, Johnson VE, Stewart W. Chronic neuropathologies of single and repetitive TBI: substrates of dementia? Nature Reviews. Neurology. 9: 211-21. PMID 23458973 DOI: 10.1038/nrneurol.2013.29  0.64
2013 Zetterberg H, Smith DH, Blennow K. Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood. Nature Reviews. Neurology. 9: 201-10. PMID 23399646 DOI: 10.1038/nrneurol.2013.9  0.64
2013 Johnson VE, Stewart JE, Begbie FD, Trojanowski JQ, Smith DH, Stewart W. Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain : a Journal of Neurology. 136: 28-42. PMID 23365092 DOI: 10.1093/brain/aws322  0.64
2013 Cullen DK, Smith DH. Bionic connections. Scientific American. 308: 52-7. PMID 23342452 DOI: 10.1038/scientificamerican0113-52  0.96
2013 Smith DH, Hicks R, Povlishock JT. Therapy development for diffuse axonal injury. Journal of Neurotrauma. 30: 307-23. PMID 23252624 DOI: 10.1089/neu.2012.2825  0.64
2013 Hanten G, Li X, Ibarra A, Wilde EA, Barnes A, McCauley SR, McCarthy J, Hoxhaj S, Mendez D, Hunter JV, Levin HS, Smith DH. Updating memory after mild traumatic brain injury and orthopedic injuries. Journal of Neurotrauma. 30: 618-24. PMID 23227898 DOI: 10.1089/neu.2012.2392  0.64
2013 Tong J, Liu W, Wang X, Han X, Hyrien O, Samadani U, Smith DH, Huang JH. Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice. Journal of Neurotrauma. 30: 247-58. PMID 22967270 DOI: 10.1089/neu.2012.2493  0.64
2013 Johnson VE, Stewart W, Smith DH. Axonal pathology in traumatic brain injury. Experimental Neurology. 246: 35-43. PMID 22285252 DOI: 10.1016/j.expneurol.2012.01.013  1
2012 Marks JA, Li S, Gong W, Sanati P, Eisenstadt R, Sims C, Smith DH, Reilly PM, Pascual JL. Similar effects of hypertonic saline and mannitol on the inflammation of the blood-brain barrier microcirculation after brain injury in a mouse model. The Journal of Trauma and Acute Care Surgery. 73: 351-7; discussion 35. PMID 22846939 DOI: 10.1097/TA.0b013e3182592f76  1
2012 Ducheyne P, Mauck RL, Smith DH. Biomaterials in the repair of sports injuries. Nature Materials. 11: 652-4. PMID 22825010 DOI: 10.1038/nmat3392  1
2012 Cullen DK, Tang-Schomer MD, Struzyna LA, Patel AR, Johnson VE, Wolf JA, Smith DH. Microtissue engineered constructs with living axons for targeted nervous system reconstruction. Tissue Engineering. Part A. 18: 2280-9. PMID 22702955 DOI: 10.1089/ten.TEA.2011.0534  1
2012 Pan Z, Hooley J, Smith DH, Young P, Roberts PE, Mather JP. Establishment of human ovarian serous carcinomas cell lines in serum free media. Methods (San Diego, Calif.). 56: 432-9. PMID 22445873 DOI: 10.1016/j.ymeth.2012.03.003  1
2012 Armstead WM, Riley J, Yarovoi S, Cines DB, Smith DH, Higazi AA. tPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury. Journal of Neurotrauma. 29: 1794-802. PMID 22435890 DOI: 10.1089/neu.2012.2328  1
2012 von Reyn CR, Mott RE, Siman R, Smith DH, Meaney DF. Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury. Journal of Neurochemistry. 121: 793-805. PMID 22428606 DOI: 10.1111/j.1471-4159.2012.07735.x  1
2012 Liu W, Ren Y, Bossert A, Wang X, Dayawansa S, Tong J, He X, Smith DH, Gelbard HA, Huang JH. Allotransplanted neurons used to repair peripheral nerve injury do not elicit overt immunogenicity. Plos One. 7: e31675. PMID 22347502 DOI: 10.1371/journal.pone.0031675  1
2012 Pisapia JM, Xu X, Kelly J, Yeung J, Carrion G, Tong H, Meghan S, El-Falaky OM, Grady MS, Smith DH, Zaitsev S, Muzykantov VR, Stiefel MF, Stein SC. Microthrombosis after experimental subarachnoid hemorrhage: time course and effect of red blood cell-bound thrombin-activated pro-urokinase and clazosentan. Experimental Neurology. 233: 357-63. PMID 22079156 DOI: 10.1016/j.expneurol.2011.10.029  1
2012 Tang-Schomer MD, Johnson VE, Baas PW, Stewart W, Smith DH. Partial interruption of axonal transport due to microtubule breakage accounts for the formation of periodic varicosities after traumatic axonal injury. Experimental Neurology. 233: 364-72. PMID 22079153 DOI: 10.1016/j.expneurol.2011.10.030  1
2012 Johnson VE, Stewart W, Smith DH. Widespread Ï„ and amyloid-β pathology many years after a single traumatic brain injury in humans. Brain Pathology (Zurich, Switzerland). 22: 142-9. PMID 21714827 DOI: 10.1111/j.1750-3639.2011.00513.x  1
2011 Johnson VE, Stewart W, Trojanowski JQ, Smith DH. Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans. Acta Neuropathologica. 122: 715-26. PMID 22101322 DOI: 10.1007/s00401-011-0909-9  1
2011 Cullen DK, Browne KD, Xu Y, Adeeb S, Wolf JA, McCarron RM, Yang S, Chavko M, Smith DH. Blast-induced color change in photonic crystals corresponds with brain pathology. Journal of Neurotrauma. 28: 2307-18. PMID 22082449 DOI: 10.1089/neu.2011.1718  1
2011 Cullen DK, Wolf JA, Smith DH, Pfister BJ. Neural tissue engineering for neuroregeneration and biohybridized interface microsystems in vivo (Part 2). Critical Reviews in Biomedical Engineering. 39: 241-59. PMID 21967304  1
2011 Vidović D, Xie Y, Rinderspacher A, Deng SX, Landry DW, Chung C, Smith DH, Tautz L, Schürer SC. Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype. Journal of Computer-Aided Molecular Design. 25: 873-83. PMID 21904909 DOI: 10.1007/s10822-011-9469-2  0.4
2011 Gong W, Marks JA, Sanati P, Sims C, Sarani B, Smith DH, Pascual JL. Hypertonic saline resuscitation of hemorrhagic shock does not decrease in vivo neutrophil interactions with endothelium in the blood-brain microcirculation. The Journal of Trauma. 71: 275-81; discussion 2. PMID 21825927 DOI: 10.1097/TA.0b013e318226eb51  1
2011 Browne KD, Chen XH, Meaney DF, Smith DH. Mild traumatic brain injury and diffuse axonal injury in swine. Journal of Neurotrauma. 28: 1747-55. PMID 21740133 DOI: 10.1089/neu.2011.1913  1
2011 Han X, Tong J, Zhang J, Farahvar A, Wang E, Yang J, Samadani U, Smith DH, Huang JH. Imipramine treatment improves cognitive outcome associated with enhanced hippocampal neurogenesis after traumatic brain injury in mice. Journal of Neurotrauma. 28: 995-1007. PMID 21463148 DOI: 10.1089/neu.2010.1563  1
2011 Rogers JT, Mikkilineni S, Cantuti-Castelvetri I, Smith DH, Huang X, Bandyopadhyay S, Cahill CM, Maccecchini ML, Lahiri DK, Greig NH. The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 493-507. PMID 21221670 DOI: 10.1007/s00702-010-0513-5  0.32
2011 Vang T, Xie Y, Liu WH, Vidović D, Liu Y, Wu S, Smith DH, Rinderspacher A, Chung C, Gong G, Mustelin T, Landry DW, Rickert RC, Schürer SC, Deng SX, et al. Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids. Journal of Medicinal Chemistry. 54: 562-71. PMID 21190368 DOI: 10.1021/jm101004d  0.4
2011 Meaney DF, Smith DH. Biomechanics of concussion. Clinics in Sports Medicine. 30: 19-31, vii. PMID 21074079 DOI: 10.1016/j.csm.2010.08.009  1
2011 Cullen DK, Xu Y, Reneer DV, Browne KD, Geddes JW, Yang S, Smith DH. Color changing photonic crystals detect blast exposure. Neuroimage. 54: S37-44. PMID 21040795 DOI: 10.1016/j.neuroimage.2010.10.076  1
2010 Haacke EM, Duhaime AC, Gean AD, Riedy G, Wintermark M, Mukherjee P, Brody DL, DeGraba T, Duncan TD, Elovic E, Hurley R, Latour L, Smirniotopoulos JG, Smith DH. Common data elements in radiologic imaging of traumatic brain injury. Journal of Magnetic Resonance Imaging : Jmri. 32: 516-43. PMID 20815050 DOI: 10.1002/jmri.22259  1
2010 Smith DH, Winters-Digiacinto P, Mitiku M, O'Rourke S, Sinangil F, Wrin T, Montefiori DC, Berman PW. Comparative immunogenicity of HIV-1 clade C envelope proteins for prime/boost studies. Plos One. 5: e12076. PMID 20711452 DOI: 10.1371/journal.pone.0012076  1
2010 Monnerie H, Tang-Schomer MD, Iwata A, Smith DH, Kim HA, Le Roux PD. Dendritic alterations after dynamic axonal stretch injury in vitro. Experimental Neurology. 224: 415-23. PMID 20478308 DOI: 10.1016/j.expneurol.2010.05.001  1
2010 Armstead WM, Ganguly K, Kiessling JW, Riley J, Chen XH, Smith DH, Stein SC, Higazi AA, Cines DB, Bdeir K, Zaitsev S, Muzykantov VR. Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders. Journal of Neurochemistry. 113: 303-12. PMID 20405577 DOI: 10.1111/j.1471-4159.2010.06613.x  1
2010 Johnson VE, Stewart W, Smith DH. Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease? Nature Reviews. Neuroscience. 11: 361-70. PMID 20216546 DOI: 10.1038/nrn2808  1
2010 Tang-Schomer MD, Patel AR, Baas PW, Smith DH. Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1401-10. PMID 20019243 DOI: 10.1096/fj.09-142844  1
2009 Pfister BJ, Chickola L, Smith DH. Head motions while riding roller coasters: implications for brain injury. The American Journal of Forensic Medicine and Pathology. 30: 339-45. PMID 19901817 DOI: 10.1097/PAF.0b013e318187e0c9  1
2009 Xie Y, Rinderspacher A, Liu Y, Gong G, Smith DH, Wyler M, Brandén L, Deng SX. Small-molecule modulators of the NF-kappaB pathway newly identified by a translocation-based cellular assay. Current Topics in Medicinal Chemistry. 9: 1172-80. PMID 19807665  0.4
2009 von Reyn CR, Spaethling JM, Mesfin MN, Ma M, Neumar RW, Smith DH, Siman R, Meaney DF. Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10350-6. PMID 19692609 DOI: 10.1523/JNEUROSCI.2339-09.2009  1
2009 Smith DH. Stretch growth of integrated axon tracts: extremes and exploitations. Progress in Neurobiology. 89: 231-9. PMID 19664679 DOI: 10.1016/j.pneurobio.2009.07.006  1
2009 Yuen TJ, Browne KD, Iwata A, Smith DH. Sodium channelopathy induced by mild axonal trauma worsens outcome after a repeat injury. Journal of Neuroscience Research. 87: 3620-5. PMID 19565655 DOI: 10.1002/jnr.22161  1
2009 Benzinger TL, Brody D, Cardin S, Curley KC, Mintun MA, Mun SK, Wong KH, Wrathall JR. Blast-related brain injury: imaging for clinical and research applications: report of the 2008 st. Louis workshop. Journal of Neurotrauma. 26: 2127-44. PMID 19508154 DOI: 10.1089/neu.2009.0885  1
2009 Armstead WM, Ganguly K, Kiessling JW, Chen XH, Smith DH, Higazi AA, Cines DB, Bdeir K, Zaitsev S, Muzykantov VR. Red blood cells-coupled tPA prevents impairment of cerebral vasodilatory responses and tissue injury in pediatric cerebral hypoxia/ischemia through inhibition of ERK MAPK activation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1463-74. PMID 19436314 DOI: 10.1038/jcbfm.2009.61  1
2009 Chen YC, Smith DH, Meaney DF. In-vitro approaches for studying blast-induced traumatic brain injury. Journal of Neurotrauma. 26: 861-76. PMID 19397424 DOI: 10.1089/neu.2008.0645  1
2009 Stein SC, Ganguly K, Belfield CM, Xu X, Swanson EW, Chen XH, Browne KD, Johnson VE, Smith DH, LeBold DG, Cines DB, Muzykantov VR, Muzykhantov VR. Erythrocyte-bound tissue plasminogen activator is neuroprotective in experimental traumatic brain injury. Journal of Neurotrauma. 26: 1585-92. PMID 19331516 DOI: 10.1089/neu.2008-0720  1
2009 Johnson VE, Stewart W, Graham DI, Stewart JE, Praestgaard AH, Smith DH. A neprilysin polymorphism and amyloid-beta plaques after traumatic brain injury. Journal of Neurotrauma. 26: 1197-202. PMID 19326964 DOI: 10.1089/neu.2008-0843  1
2009 Xie Y, Liu Y, Gong G, Smith DH, Yan F, Rinderspacher A, Feng Y, Zhu Z, Li X, Deng SX, Branden L, Vidović D, Chung C, Schürer S, Morisseau C, et al. Discovery of potent non-urea inhibitors of soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters. 19: 2354-9. PMID 19303288 DOI: 10.1016/j.bmcl.2008.09.066  0.4
2009 Carlile GW, Smith DH, Wiedmann M. A non-apoptotic role for Fas/FasL in erythropoiesis. Febs Letters. 583: 848-54. PMID 19244619 DOI: 10.1016/j.febslet.2009.01.047  0.32
2009 Huang JH, Cullen DK, Browne KD, Groff R, Zhang J, Pfister BJ, Zager EL, Smith DH. Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration. Tissue Engineering. Part A. 15: 1677-85. PMID 19231968 DOI: 10.1089/ten.tea.2008.0294  1
2009 Gong G, Xie Y, Liu Y, Rinderspacher A, Deng SX, Feng Y, Zhu Z, Tang Y, Wyler M, Aulner N, Toebben U, Smith DH, Branden L, Chung C, Schürer S, et al. Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation. Bioorganic & Medicinal Chemistry Letters. 19: 1191-4. PMID 19136257 DOI: 10.1016/j.bmcl.2008.12.086  0.4
2009 Chen XH, Johnson VE, Uryu K, Trojanowski JQ, Smith DH. A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury. Brain Pathology (Zurich, Switzerland). 19: 214-23. PMID 18492093 DOI: 10.1111/j.1750-3639.2008.00176.x  1
2008 Kameswaran N, Cullen DK, Pfister BJ, Ranalli NJ, Huang JH, Zager EL, Smith DH. A novel neuroprosthetic interface with the peripheral nervous system using artificially engineered axonal tracts. Neurological Research. 30: 1063-7. PMID 19079981 DOI: 10.1179/174313208X362541  1
2008 Rogers JT, Bush AI, Cho HH, Smith DH, Thomson AM, Friedlich AL, Lahiri DK, Leedman PJ, Huang X, Cahill CM. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. Biochemical Society Transactions. 36: 1282-7. PMID 19021541 DOI: 10.1042/BST0361282  0.32
2008 Cullen DK, R Patel A, Doorish JF, Smith DH, Pfister BJ. Developing a tissue-engineered neural-electrical relay using encapsulated neuronal constructs on conducting polymer fibers. Journal of Neural Engineering. 5: 374-84. PMID 18827311 DOI: 10.1088/1741-2560/5/4/002  1
2008 Xie Y, Liu Y, Gong G, Rinderspacher A, Deng SX, Smith DH, Toebben U, Tzilianos E, Branden L, Vidović D, Chung C, Schürer S, Tautz L, Landry DW. Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase. Bioorganic & Medicinal Chemistry Letters. 18: 2840-4. PMID 18434147 DOI: 10.1016/j.bmcl.2008.03.079  0.32
2008 Zhang J, Groff RF, Chen XH, Browne KD, Huang J, Schwartz ED, Meaney DF, Johnson VE, Stein SC, Rojkjaer R, Smith DH. Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs. Experimental Neurology. 210: 645-55. PMID 18291370 DOI: 10.1016/j.expneurol.2007.12.019  1
2008 Huang JH, Zager EL, Zhang J, Groff RF, Pfister BJ, Cohen AS, Grady MS, Maloney-Wilensky E, Smith DH. Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation. Laboratory investigation. Journal of Neurosurgery. 108: 343-7. PMID 18240932 DOI: 10.3171/JNS/2008/108/2/0343  1
2008 Xie Y, Deng S, Thomas CJ, Liu Y, Zhang YQ, Rinderspacher A, Huang W, Gong G, Wyler M, Cayanis E, Aulner N, Többen U, Chung C, Pampou S, Southall N, ... ... Smith DH, et al. Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation. Bioorganic & Medicinal Chemistry Letters. 18: 329-35. PMID 18024113 DOI: 10.1016/j.bmcl.2007.10.100  0.32
2007 Uryu K, Chen XH, Martinez D, Browne KD, Johnson VE, Graham DI, Lee VM, Trojanowski JQ, Smith DH. Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Experimental Neurology. 208: 185-92. PMID 17826768 DOI: 10.1016/j.expneurol.2007.06.018  1
2007 Pfister BJ, Huang JH, Kameswaran N, Zager EL, Smith DH. Neural engineering to produce in vitro nerve constructs and neurointerface. Neurosurgery. 60: 137-41; discussion 1. PMID 17228262 DOI: 10.1227/01.NEU.0000249197.61280.1D  1
2007 Armstead WM, Chen XH, Smith DH. NOC/oFQ antagonist post injury treatment protects against cerebral circulatory collapse and histopathology after combined prolonged hypotension and brain injury Journal of Cerebral Blood Flow and Metabolism. 27: BO01-04.  1
2007 Zhang J, Xu BN, Zhou DB, Smith DH. Living tissue-engineered nerve transplant bridging sciatic nerve lesion: Quantitative evaluation of survival time and functional restoration Journal of Clinical Rehabilitative Tissue Engineering Research. 11: 3018-3021.  1
2006 Armstead WM, Nassar T, Akkawi S, Smith DH, Chen XH, Cines DB, Higazi AA. Neutralizing the neurotoxic effects of exogenous and endogenous tPA. Nature Neuroscience. 9: 1150-5. PMID 16936723 DOI: 10.1038/nn1757  1
2006 Stein SC, Browne KD, Chen XH, Smith DH, Graham DI. Thromboembolism and delayed cerebral ischemia after subarachnoid hemorrhage: an autopsy study. Neurosurgery. 59: 781-7; discussion 78. PMID 16915120 DOI: 10.1227/01.NEU.0000227519.27569.45  1
2006 Maxwell WL, MacKinnon MA, Smith DH, McIntosh TK, Graham DI. Thalamic nuclei after human blunt head injury. Journal of Neuropathology and Experimental Neurology. 65: 478-88. PMID 16772871 DOI: 10.1097/01.jnen.0000229241.28619.75  1
2006 Browne KD, Iwata A, Putt ME, Smith DH. Chronic ibuprofen administration worsens cognitive outcome following traumatic brain injury in rats. Experimental Neurology. 201: 301-7. PMID 16764859 DOI: 10.1016/j.expneurol.2006.04.008  1
2006 Pfister BJ, Bonislawski DP, Smith DH, Cohen AS. Stretch-grown axons retain the ability to transmit active electrical signals. Febs Letters. 580: 3525-31. PMID 16730003 DOI: 10.1016/j.febslet.2006.05.030  1
2006 Iwata A, Browne KD, Pfister BJ, Gruner JA, Smith DH. Long-term survival and outgrowth of mechanically engineered nervous tissue constructs implanted into spinal cord lesions. Tissue Engineering. 12: 101-10. PMID 16499447 DOI: 10.1089/ten.2006.12.101  1
2006 Pfister BJ, Iwata A, Taylor AG, Wolf JA, Meaney DF, Smith DH. Development of transplantable nervous tissue constructs comprised of stretch-grown axons. Journal of Neuroscience Methods. 153: 95-103. PMID 16337007 DOI: 10.1016/j.jneumeth.2005.10.012  1
2006 Jette N, Coderre E, Nikolaeva MA, Enright PD, Iwata A, Smith DH, Jiang Q, Stys PK. Spatiotemporal distribution of spectrin breakdown products induced by anoxia in adult rat optic nerve in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 777-86. PMID 16163297 DOI: 10.1038/sj.jcbfm.9600226  1
2005 Iwata A, Browne KD, Chen XH, Yuguchi T, Smith DH. Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats. Journal of Neuroscience Research. 82: 103-14. PMID 16118797 DOI: 10.1002/jnr.20607  1
2005 Stein SC, Graham DI, Chen XH, Dunn L, Smith DH. Apo E genotype not associated with intravascular coagulation in traumatic brain injury. Neuroscience Letters. 387: 28-31. PMID 16084020 DOI: 10.1016/j.neulet.2005.07.011  1
2004 Stein SC, Smith DH. Coagulopathy in traumatic brain injury. Neurocritical Care. 1: 479-88. PMID 16174954 DOI: 10.1385/NCC:1:4:479  1
2004 Lusardi TA, Rangan J, Sun D, Smith DH, Meaney DF. A device to study the initiation and propagation of calcium transients in cultured neurons after mechanical stretch. Annals of Biomedical Engineering. 32: 1546-58. PMID 15636114 DOI: 10.1114/B:ABME.0000049038.75368.75  1
2004 Vijayvergiya C, De Angelis D, Walther M, Kühn H, Duvoisin RM, Smith DH, Wiedmann M. High-level expression of rabbit 15-lipoxygenase induces collapse of the mitochondrial pH gradient in cell culture. Biochemistry. 43: 15296-302. PMID 15568822 DOI: 10.1021/bi048745v  0.32
2004 Maxwell WL, Pennington K, MacKinnon MA, Smith DH, McIntosh TK, Wilson JT, Graham DI. Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury. Brain : a Journal of Neurology. 127: 2470-8. PMID 15456707 DOI: 10.1093/brain/awh294  1
2004 Pfister BJ, Iwata A, Meaney DF, Smith DH. Extreme stretch growth of integrated axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7978-83. PMID 15356212 DOI: 10.1523/JNEUROSCI.1974-04.2004  1
2004 Browne KD, Leoni MJ, Iwata A, Chen XH, Smith DH. Acute treatment with MgSO4 attenuates long-term hippocampal tissue loss after brain trauma in the rat. Journal of Neuroscience Research. 77: 878-83. PMID 15334605 DOI: 10.1002/jnr.20215  1
2004 Chen XH, Siman R, Iwata A, Meaney DF, Trojanowski JQ, Smith DH. Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma. The American Journal of Pathology. 165: 357-71. PMID 15277212 DOI: 10.1016/S0002-9440(10)63303-2  1
2004 Ledergerber B, Lundgren JD, Walker AS, Sabin C, Justice A, Reiss P, Mussini C, Wit F, d'Arminio Monforte A, Weber R, Fusco G, Staszewski S, Law M, Hogg R, Lampe F, et al. Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes. Lancet. 364: 51-62. PMID 15234856 DOI: 10.1016/S0140-6736(04)16589-6  1
2004 Iwata A, Stys PK, Wolf JA, Chen XH, Taylor AG, Meaney DF, Smith DH. Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4605-13. PMID 15140932 DOI: 10.1523/JNEUROSCI.0515-03.2004  1
2004 Stein SC, Graham DI, Chen XH, Smith DH. Association between intravascular microthrombosis and cerebral ischemia in traumatic brain injury. Neurosurgery. 54: 687-91; discussion 6. PMID 15028145  1
2004 Lusardi TA, Wolf JA, Putt ME, Smith DH, Meaney DF. Effect of acute calcium influx after mechanical stretch injury in vitro on the viability of hippocampal neurons. Journal of Neurotrauma. 21: 61-72. PMID 14987466 DOI: 10.1089/089771504772695959  1
2004 Carlile GW, Smith DH, Wiedmann M. Caspase-3 has a nonapoptotic function in erythroid maturation. Blood. 103: 4310-6. PMID 14976035 DOI: 10.1182/blood-2003-09-3362  0.32
2003 Smith DH, Meaney DF, Shull WH. Diffuse axonal injury in head trauma. The Journal of Head Trauma Rehabilitation. 18: 307-16. PMID 16222127  1
2003 Smith DH, Uryu K, Saatman KE, Trojanowski JQ, McIntosh TK. Protein accumulation in traumatic brain injury. Neuromolecular Medicine. 4: 59-72. PMID 14528053 DOI: 10.1385/NMM:4:1-2:59  1
2003 Chen XH, Iwata A, Nonaka M, Browne KD, Smith DH. Neurogenesis and glial proliferation persist for at least one year in the subventricular zone following brain trauma in rats. Journal of Neurotrauma. 20: 623-31. PMID 12908924 DOI: 10.1089/089771503322144545  1
2003 Smith DH, Chen XH, Iwata A, Graham DI. Amyloid beta accumulation in axons after traumatic brain injury in humans. Journal of Neurosurgery. 98: 1072-7. PMID 12744368 DOI: 10.3171/jns.2003.98.5.1072  1
2003 Maxwell WL, Dhillon K, Harper L, Espin J, MacIntosh TK, Smith DH, Graham DI. There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injury. Journal of Neuropathology and Experimental Neurology. 62: 272-9. PMID 12638731  1
2003 Saatman KE, Abai B, Grosvenor A, Vorwerk CK, Smith DH, Meaney DF. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 34-42. PMID 12500089  1
2003 Lusardi TA, Smith DH, Wolf JA, Meaney DF. The separate roles of calcium and mechanical forces in mediating cell death in mechanically injured neurons. Biorheology. 40: 401-9. PMID 12454433  1
2002 Stein SC, Chen XH, Sinson GP, Smith DH. Intravascular coagulation: a major secondary insult in nonfatal traumatic brain injury. Journal of Neurosurgery. 97: 1373-7. PMID 12507136 DOI: 10.3171/jns.2002.97.6.1373  1
2002 Iwata A, Chen XH, McIntosh TK, Browne KD, Smith DH. Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. Journal of Neuropathology and Experimental Neurology. 61: 1056-68. PMID 12484568  1
2002 Smith DH, Meaney DF. Roller coasters, g forces, and brain trauma: on the wrong track? Journal of Neurotrauma. 19: 1117-20. PMID 12427321 DOI: 10.1089/08977150260337921  1
2001 Meaney DF, Margulies SS, Smith DH. Diffuse axonal injury. Journal of Neurosurgery. 95: 1108-10. PMID 11765833  1
2001 Smith DH, Wolf JA, Meaney DF. A new strategy to produce sustained growth of central nervous system axons: continuous mechanical tension. Tissue Engineering. 7: 131-9. PMID 11304449 DOI: 10.1089/107632701300062714  1
2001 Wolf JA, Stys PK, Lusardi T, Meaney D, Smith DH. Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1923-30. PMID 11245677  1
2001 Yoon M, Smith DH, Ward P, Medrano FJ, Aggarwal AK, Linden RM. Amino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro. Journal of Virology. 75: 3230-9. PMID 11238849 DOI: 10.1128/JVI.75.7.3230-3239.2001  0.32
2001 Smith DH, Wolf JA, Meaney DF. Tissue engineering of CNS axonal tracts using mechanically induced growth American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 413-414.  1
2001 Lusardi TA, Smith DH, Wolf JA, DeRidder MN, Meaney DF. Mechanical stretch of cultured neurons: Relationships between acute cytosolic calcium changes and cell death American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 615-616.  1
2000 Leoni MJ, Chen XH, Mueller AL, Cheney J, McIntosh TK, Smith DH. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Experimental Neurology. 166: 442-9. PMID 11085909 DOI: 10.1006/exnr.2000.7513  1
2000 Patel SD, Moskalenko M, Tian T, Smith D, McGuinness R, Chen L, Winslow GA, Kashmiri S, Schlom J, Stanners CP, Finer MH, McArthur JG. T-cell killing of heterogenous tumor or viral targets with bispecific chimeric immune receptors. Cancer Gene Therapy. 7: 1127-34. PMID 10975673 DOI: 10.1038/sj.cgt.7700213  1
2000 Smith DH, Nonaka M, Miller R, Leoni M, Chen XH, Alsop D, Meaney DF. Immediate coma following inertial brain injury dependent on axonal damage in the brainstem. Journal of Neurosurgery. 93: 315-22. PMID 10930019 DOI: 10.3171/jns.2000.93.2.0315  1
2000 Nakagawa Y, Reed L, Nakamura M, McIntosh TK, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Lee VM, Trojanowski JQ. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Experimental Neurology. 163: 244-52. PMID 10785464 DOI: 10.1006/exnr.2000.7375  1
2000 Tang YW, Von Graevenitz A, Waddington MG, Hopkins MK, Smith DH, Li H, Kolbert CP, Montgomery SO, Persing DH. Identification of coryneform bacterial isolates by ribosomal DNA sequence analysis Journal of Clinical Microbiology. 38: 1676-1678. PMID 10747168  1
2000 Tang YW, Waddington MG, Smith DH, Manahan JM, Kohner PC, Highsmith LM, Li H, Cockerill FR, Thompson RL, Montgomery SO, Persing DH. Comparison of protein A gene sequencing with pulsed-field gel electrophoresis and epidemiologic data for molecular typing of methicillin- resistant Staphylococcus aureus Journal of Clinical Microbiology. 38: 1347-1351. PMID 10747105  1
2000 Petropoulos CJ, Parkin NT, Limoli KL, Lie YS, Wrin T, Huang W, Tian H, Smith D, Winslow GA, Capon DJ, Whitcomb JM. A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1 Antimicrobial Agents and Chemotherapy. 44: 920-928. PMID 10722492 DOI: 10.1128/AAC.44.4.920-928.2000  1
2000 Smith DH, Meaney DF. Axonal damage in traumatic brain injury Neuroscientist. 6: 483-495.  1
1999 Nonaka M, Chen XH, Pierce JE, Leoni MJ, McIntosh TK, Wolf JA, Smith DH. Prolonged activation of NF-kappaB following traumatic brain injury in rats. Journal of Neurotrauma. 16: 1023-34. PMID 10595819  1
1999 Shopsin B, Gomez M, Montgomery SO, Smith DH, Waddington M, Dodge DE, Bost DA, Riehman M, Naidich S, Kreiswirth BN. Evaluation of protein A gene polymorphic region DNA sequencing for typing of Staphylococcus aureus strains. Journal of Clinical Microbiology. 37: 3556-63. PMID 10523551  1
1999 Smith DH, Chen XH, Nonaka M, Trojanowski JQ, Lee VM, Saatman KE, Leoni MJ, Xu BN, Wolf JA, Meaney DF. Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 982-92. PMID 10499440  1
1999 Nakagawa Y, Nakamura M, McIntosh TK, Rodriguez A, Berlin JA, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Schmidt ML, Lee VM, Trojanowski JQ. Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging. The Journal of Comparative Neurology. 411: 390-8. PMID 10413774 DOI: 10.1002/(SICI)1096-9861(19990830)411:3<390::AID-CNE3>3.0.CO;2-#  1
1999 Chen XH, Meaney DF, Xu BN, Nonaka M, McIntosh TK, Wolf JA, Saatman KE, Smith DH. Evolution of neurofilament subtype accumulation in axons following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 588-96. PMID 10374749  1
1999 Smith DH, Wolf JA, Lusardi TA, Lee VM, Meaney DF. High tolerance and delayed elastic response of cultured axons to dynamic stretch injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4263-9. PMID 10341230  1
1999 McGowan JC, McCormack TM, Grossman RI, Mendonça R, Chen XH, Berlin JA, Meaney DF, Xu BN, Cecil KM, McIntosh TK, Smith DH. Diffuse axonal pathology detected with magnetization transfer imaging following brain injury in the pig. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 41: 727-33. PMID 10332848 DOI: 10.1002/(SICI)1522-2594(199904)41:4<727::AID-MRM11>3.0.CO;2-6  1
1999 Shreiber DI, Bain AC, Ross DT, Smith DH, Gennarelli TA, McIntosh TK, Meaney DF. Experimental investigation of cerebral contusion: histopathological and immunohistochemical evaluation of dynamic cortical deformation. Journal of Neuropathology and Experimental Neurology. 58: 153-64. PMID 10029098  1
1999 Miller RT, Smith DH, Chen X, Xu BN, Leoni M, Nonaka M, Meaney DF. Comparing experimental data to traumatic brain injury finite element models Stapp Car Crash Conference Proceedings. 303-311.  1
1999 Meaney DF, Ewoterai I, Wolf JA, Lusardi TG, Smith DH. Mechanical recovery of cultured axons after dynamic stretch: correlation to cytoskeletal changes American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 44: 45-49.  1
1998 McIntosh TK, Saatman KE, Raghupathi R, Graham DI, Smith DH, Lee VM, Trojanowski JQ. The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathology and Applied Neurobiology. 24: 251-67. PMID 9775390 DOI: 10.1046/j.1365-2990.1998.00121.x  1
1998 Smith DH, Cecil KM, Meaney DF, Chen XH, McIntosh TK, Gennarelli TA, Lenkinski RE. Magnetic resonance spectroscopy of diffuse brain trauma in the pig. Journal of Neurotrauma. 15: 665-74. PMID 9753214  1
1998 Pierce JE, Smith DH, Trojanowski JQ, McIntosh TK. Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience. 87: 359-69. PMID 9740398 DOI: 10.1016/S0306-4522(98)00142-0  1
1998 Smith DH, Nakamura M, McIntosh TK, Wang J, Rodríguez A, Chen XH, Raghupathi R, Saatman KE, Clemens J, Schmidt ML, Lee VM, Trojanowski JQ. Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein. The American Journal of Pathology. 153: 1005-10. PMID 9736050 DOI: 10.1016/S0002-9440(10)65643-X  1
1998 Okiyama K, Smith DH, White WF, McIntosh TK. Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat. Brain Research. 792: 291-8. PMID 9593949 DOI: 10.1016/S0006-8993(98)00158-9  1
1998 Zhang C, Raghupathi R, Saatman KE, Smith DH, Stutzmann JM, Wahl F, McIntosh TK. Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat. Journal of Neuroscience Research. 52: 342-9. PMID 9590442 DOI: 10.1002/(SICI)1097-4547(19980501)52:3<342::AID-JNR10>3.0.CO;2-8  1
1998 Cecil KM, Hills EC, Sandel ME, Smith DH, McIntosh TK, Mannon LJ, Sinson GP, Bagley LJ, Grossman RI, Lenkinski RE. Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients. Journal of Neurosurgery. 88: 795-801. PMID 9576245 DOI: 10.3171/jns.1998.88.5.0795  1
1998 Cecil KM, Lenkinski RE, Meaney DF, McIntosh TK, Smith DH. High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. Journal of Neurochemistry. 70: 2038-44. PMID 9572290  1
1998 Murai H, Pierce JE, Raghupathi R, Smith DH, Saatman KE, Trojanowski JQ, Lee VM, Loring JF, Eckman C, Younkin S, McIntosh TK. Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury. The Journal of Comparative Neurology. 392: 428-38. PMID 9514508 DOI: 10.1002/(SICI)1096-9861(19980323)392:4<428::AID-CNE2>3.0.CO;2-2  1
1997 Smith DH, Chen XH, Pierce JE, Wolf JA, Trojanowski JQ, Graham DI, McIntosh TK. Progressive atrophy and neuron death for one year following brain trauma in the rat. Journal of Neurotrauma. 14: 715-27. PMID 9383090  1
1997 Saatman KE, Contreras PC, Smith DH, Raghupathi R, McDermott KL, Fernandez SC, Sanderson KL, Voddi M, McIntosh TK. Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury. Experimental Neurology. 147: 418-27. PMID 9344566 DOI: 10.1006/exnr.1997.6629  1
1997 Smith DH, Perri BR, Raghupathi R, Saatman KE, McIntosh TK. Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat. Neuroscience Letters. 231: 135-8. PMID 9300640 DOI: 10.1016/S0304-3940(97)00551-X  1
1997 Rubin Y, Cecil K, Wehrli S, McIntosh TK, Lenkinski RE, Smith DH. High-resolution 1H NMR spectroscopy following experimental brain trauma. Journal of Neurotrauma. 14: 441-9. PMID 9257662 DOI: 10.1089/neu.1997.14.441  1
1997 McIntosh TK, Garde E, Saatman KE, Smith DH. Central nervous system resuscitation. Emergency Medicine Clinics of North America. 15: 527-50. PMID 9255131 DOI: 10.1016/S0733-8627(05)70316-3  1
1997 Smith DH, Chen XH, Xu BN, McIntosh TK, Gennarelli TA, Meaney DF. Characterization of diffuse axonal pathology and selective hippocampal damage following inertial brain trauma in the pig. Journal of Neuropathology and Experimental Neurology. 56: 822-34. PMID 9210879  1
1997 Okiyama K, Smith DH, White WF, Richter K, McIntosh TK. Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat. Journal of Neurotrauma. 14: 211-22. PMID 9151770  1
1997 McDermott KL, Raghupathi R, Fernandez SC, Saatman KE, Protter AA, Finklestein SP, Sinson G, Smith DH, McIntosh TK. Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat. Journal of Neurotrauma. 14: 191-200. PMID 9151768  1
1997 Perri BR, Smith DH, Murai H, Sinson G, Saatman KE, Raghupathi R, Bartus RT, McIntosh TK. Metabolic quantification of lesion volume following experimental traumatic brain injury in the rat. Journal of Neurotrauma. 14: 15-22. PMID 9048307  1
1996 McIntosh TK, Smith DH, Voddi M, Perri BR, Stutzmann JM. Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. Journal of Neurotrauma. 13: 767-80. PMID 9002062  1
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