| Year |
Citation |
Score |
| 2016 |
Greeley SA, Zielinski MC, Poudel A, Ye H, Berry S, Taxy JB, Carmody D, Steiner DF, Philipson LH, Wood JR, Hara M. Case Report: Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-related Diabetes. The Journal of Clinical Endocrinology and Metabolism. jc20162826. PMID 27802092 DOI: 10.1210/Jc.2016-2826 |
0.382 |
|
| 2014 |
Menting JG, Yang Y, Chan SJ, Phillips NB, Smith BJ, Whittaker J, Wickramasinghe NP, Whittaker LJ, Pandyarajan V, Wan ZL, Yadav SP, Carroll JM, Strokes N, Roberts CT, Ismail-Beigi F, ... ... Steiner DF, et al. Protective hinge in insulin opens to enable its receptor engagement. Proceedings of the National Academy of Sciences of the United States of America. 111: E3395-404. PMID 25092300 DOI: 10.1073/Pnas.1412897111 |
0.377 |
|
| 2013 |
Kanatsuna N, Taneera J, Vaziri-Sani F, Wierup N, Larsson HE, Delli A, Skärstrand H, Balhuizen A, Bennet H, Steiner DF, Törn C, Fex M, Lernmark Å. Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets. The Journal of Biological Chemistry. 288: 29013-23. PMID 23935095 DOI: 10.1074/Jbc.M113.478222 |
0.49 |
|
| 2013 |
Menting JG, Whittaker J, Margetts MB, Whittaker LJ, Kong GK, Smith BJ, Watson CJ, Záková L, KletvÃková E, JiráÄek J, Chan SJ, Steiner DF, Dodson GG, Brzozowski AM, Weiss MA, et al. How insulin engages its primary binding site on the insulin receptor. Nature. 493: 241-5. PMID 23302862 DOI: 10.1038/Nature11781 |
0.465 |
|
| 2012 |
Cyr NE, Stuart RC, Zhu X, Steiner DF, Nillni EA. Biosynthesis of proTRH-derived peptides in prohormone convertase 1 and 2 knockout mice. Peptides. 35: 42-8. PMID 22421509 DOI: 10.1016/J.Peptides.2012.02.024 |
0.369 |
|
| 2011 |
Steiner DF. On the discovery of precursor processing. Methods in Molecular Biology (Clifton, N.J.). 768: 3-11. PMID 21805235 DOI: 10.1007/978-1-61779-204-5_1 |
0.549 |
|
| 2011 |
Steiner DF. Adventures with insulin in the islets of Langerhans. The Journal of Biological Chemistry. 286: 17399-421. PMID 21454641 DOI: 10.1074/Jbc.X111.244764 |
0.491 |
|
| 2011 |
Støy J, Steiner DF, Park S, Ye H, Philipson LH, Bell GI. Erratum to: Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene Reviews in Endocrine and Metabolic Disorders. 13: 79-81. DOI: 10.1007/S11154-011-9158-4 |
0.327 |
|
| 2011 |
Steiner DF, Chan SJ, Rubenstein AH. Biosynthesis of Insulin Comprehensive Physiology. 49-78. DOI: 10.1002/Cphy.Cp070203 |
0.494 |
|
| 2010 |
Vlacich G, Nawijn MC, Webb GC, Steiner DF. Pim3 negatively regulates glucose-stimulated insulin secretion. Islets. 2: 308-17. PMID 21099329 DOI: 10.4161/Isl.2.5.13058 |
0.408 |
|
| 2010 |
Støy J, Steiner DF, Park SY, Ye H, Philipson LH, Bell GI. Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. Reviews in Endocrine & Metabolic Disorders. 11: 205-15. PMID 20938745 DOI: 10.1007/S11154-010-9151-3 |
0.322 |
|
| 2010 |
Kilimnik G, Kim A, Steiner DF, Friedman TC, Hara M. Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration. Islets. 2: 149-55. PMID 20657753 DOI: 10.4161/Isl.2.3.11396 |
0.384 |
|
| 2010 |
Wardman JH, Zhang X, Gagnon S, Castro LM, Zhu X, Steiner DF, Day R, Fricker LD. Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics. Journal of Neurochemistry. 114: 215-25. PMID 20412386 DOI: 10.1111/J.1471-4159.2010.06760.X |
0.369 |
|
| 2010 |
Smith BJ, Huang K, Kong G, Chan SJ, Nakagawa S, Menting JG, Hu SQ, Whittaker J, Steiner DF, Katsoyannis PG, Ward CW, Weiss MA, Lawrence MC. Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists. Proceedings of the National Academy of Sciences of the United States of America. 107: 6771-6. PMID 20348418 DOI: 10.1073/Pnas.1001813107 |
0.474 |
|
| 2010 |
Park SY, Ye H, Steiner DF, Bell GI. Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted. Biochemical and Biophysical Research Communications. 391: 1449-54. PMID 20034470 DOI: 10.1016/J.Bbrc.2009.12.090 |
0.385 |
|
| 2010 |
Zhang X, Pan H, Peng B, Steiner DF, Pintar JE, Fricker LD. Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis. Journal of Neurochemistry. 112: 1168-79. PMID 19968759 DOI: 10.1111/J.1471-4159.2009.06530.X |
0.373 |
|
| 2010 |
Steiner DF, Oyer PE. The biosynthesis of insulin and a probable precursor of insulin by a human islet cell adenoma. Proceedings of the National Academy of Sciences of the United States of America. 57: 473-80. PMID 16591494 DOI: 10.1073/Pnas.57.2.473 |
0.481 |
|
| 2009 |
Steiner DF, Park SY, Støy J, Philipson LH, Bell GI. A brief perspective on insulin production. Diabetes, Obesity & Metabolism. 11: 189-96. PMID 19817801 DOI: 10.1111/J.1463-1326.2009.01106.X |
0.513 |
|
| 2009 |
Kharouta M, Miller K, Kim A, Wojcik P, Kilimnik G, Dey A, Steiner DF, Hara M. No mantle formation in rodent islets -- the prototype of islet revisited. Diabetes Research and Clinical Practice. 85: 252-7. PMID 19595468 DOI: 10.1016/J.Diabres.2009.06.021 |
0.37 |
|
| 2009 |
Bass J, Kristensen C, Andersen AS, Wiberg FC, Schäffer L, Kjeldsen T, Steiner DF. P-12: Expression, characterization and purification of soluble insulin receptor-immunoglobulin chimeras that retain high-affinity insulin binding Experimental and Clinical Endocrinology & Diabetes. 104: 77-78. DOI: 10.1055/S-0029-1211555 |
0.437 |
|
| 2008 |
Rehfeld JF, Zhu X, Norrbom C, Bundgaard JR, Johnsen AH, Nielsen JE, Vikesaa J, Stein J, Dey A, Steiner DF, Friis-Hansen L. Prohormone convertases 1/3 and 2 together orchestrate the site-specific cleavages of progastrin to release gastrin-34 and gastrin-17. The Biochemical Journal. 415: 35-43. PMID 18554181 DOI: 10.1042/Bj20080881 |
0.345 |
|
| 2008 |
Molven A, Ringdal M, Nordbø AM, Raeder H, Støy J, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, Undlien DE, Joner G, Søvik O, Bell GI, et al. Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes. 57: 1131-5. PMID 18192540 DOI: 10.2337/Db07-1467 |
0.339 |
|
| 2008 |
Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Støy J, Steiner DF, Philipson LH, Bell GI, et al. Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes. 57: 1034-42. PMID 18162506 DOI: 10.2337/Db07-1405 |
0.308 |
|
| 2008 |
Rehfeld JF, Bundgaard JR, Hannibal J, Zhu X, Norrbom C, Steiner DF, Friis-Hansen L. The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6. Endocrinology. 149: 1600-8. PMID 18096669 DOI: 10.1210/En.2007-0278 |
0.36 |
|
| 2008 |
Steiner DF. The biosynthesis of insulin Pancreatic Beta Cell in Health and Disease. 31-49. DOI: 10.1007/978-4-431-75452-7_3 |
0.358 |
|
| 2007 |
Huang K, Chan SJ, Hua QX, Chu YC, Wang RY, Klaproth B, Jia W, Whittaker J, De Meyts P, Nakagawa SH, Steiner DF, Katsoyannis PG, Weiss MA. The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice. The Journal of Biological Chemistry. 282: 35337-49. PMID 17884811 DOI: 10.1074/Jbc.M705996200 |
0.364 |
|
| 2007 |
Støy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SA, Patch AM, Ellard S, Steiner DF, et al. Insulin gene mutations as a cause of permanent neonatal diabetes. Proceedings of the National Academy of Sciences of the United States of America. 104: 15040-4. PMID 17855560 DOI: 10.1073/Pnas.0707291104 |
0.381 |
|
| 2007 |
Kedees MH, Guz Y, Vuguin PM, Vargas C, Cui L, Steiner DF, Charron MJ, Teitelman G. Nestin expression in pancreatic endocrine and exocrine cells of mice lacking glucagon signaling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 1126-33. PMID 17366624 DOI: 10.1002/Dvdy.21112 |
0.353 |
|
| 2007 |
Chan SJ, Nakagawa S, Steiner DF. Complementation analysis demonstrates that insulin cross-links both alpha subunits in a truncated insulin receptor dimer. The Journal of Biological Chemistry. 282: 13754-8. PMID 17339314 DOI: 10.1074/Jbc.M700724200 |
0.452 |
|
| 2007 |
Huang K, Chan S, Hua Q, Chu Y, Wang R, Klaproth B, Jia W, Whittaker J, Meyts PD, Nakagawa S, Steiner D, Katsoyannis P, Weiss M. ThrA3-DKP-insulin Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15450 |
0.458 |
|
| 2006 |
Zhu X, Cao Y, Voogd K, Voodg K, Steiner DF. On the processing of proghrelin to ghrelin. The Journal of Biological Chemistry. 281: 38867-70. PMID 17050541 DOI: 10.1074/Jbc.M607955200 |
0.381 |
|
| 2006 |
Pan H, Che FY, Peng B, Steiner DF, Pintar JE, Fricker LD. The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study. Journal of Neurochemistry. 98: 1763-77. PMID 16903874 DOI: 10.1111/J.1471-4159.2006.04067.X |
0.376 |
|
| 2006 |
Marzban L, Rhodes CJ, Steiner DF, Haataja L, Halban PA, Verchere CB. Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death. Diabetes. 55: 2192-201. PMID 16873681 DOI: 10.2337/Db05-1566 |
0.342 |
|
| 2006 |
Wang J, Cao Y, Chen Y, Chen Y, Gardner P, Steiner DF. Pancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survival. Proceedings of the National Academy of Sciences of the United States of America. 103: 10636-41. PMID 16815968 DOI: 10.1073/Pnas.0604194103 |
0.321 |
|
| 2006 |
Stein J, Shah R, Steiner DF, Dey A. RNAi-mediated silencing of prohormone convertase (PC) 5/6 expression leads to impairment in processing of cocaine- and amphetamine-regulated transcript (CART) precursor. The Biochemical Journal. 400: 209-15. PMID 16800814 DOI: 10.1042/Bj20060506 |
0.324 |
|
| 2006 |
Stein J, Steiner DF, Dey A. Processing of cocaine- and amphetamine-regulated transcript (CART) precursor proteins by prohormone convertases (PCs) and its implications. Peptides. 27: 1919-25. PMID 16784796 DOI: 10.1016/J.Peptides.2005.10.028 |
0.349 |
|
| 2006 |
Schlueter PJ, Royer T, Farah MH, Laser B, Chan SJ, Steiner DF, Duan C. Gene duplication and functional divergence of the zebrafish insulin-like growth factor 1 receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1230-2. PMID 16705083 DOI: 10.1096/Fj.05-3882Fje |
0.357 |
|
| 2006 |
Ugleholdt R, Poulsen ML, Holst PJ, Irminger JC, Orskov C, Pedersen J, Rosenkilde MM, Zhu X, Steiner DF, Holst JJ. Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor. The Journal of Biological Chemistry. 281: 11050-7. PMID 16476726 DOI: 10.1074/Jbc.M601203200 |
0.353 |
|
| 2006 |
Creemers JW, Pritchard LE, Gyte A, Le Rouzic P, Meulemans S, Wardlaw SL, Zhu X, Steiner DF, Davies N, Armstrong D, Lawrence CB, Luckman SM, Schmitz CA, Davies RA, Brennand JC, et al. Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3. Endocrinology. 147: 1621-31. PMID 16384863 DOI: 10.1210/En.2005-1373 |
0.353 |
|
| 2006 |
Steiner DF, Boitard C, Cerasi E, Efendic S, Henquin JC, Ferrannini E. Toward a systems biology of insulin secretion and type 2 diabetes Diabetes. 55: S1-S4. DOI: 10.2337/Db06-S000 |
0.474 |
|
| 2005 |
Boitard C, Efendic S, Ferrannini E, Henquin JC, Steiner DF, Cerasi E. A tale of two cousins: type 1 and type 2 diabetes. Diabetes. 54: S1-3. PMID 16306326 DOI: 10.2337/Diabetes.54.Suppl_2.S1 |
0.3 |
|
| 2005 |
Hardiman A, Friedman TC, Grunwald WC, Furuta M, Zhu Z, Steiner DF, Cool DR. Endocrinomic profile of neurointermediate lobe pituitary prohormone processing in PC1/3- and PC2-Null mice using SELDI-TOF mass spectrometry. Journal of Molecular Endocrinology. 34: 739-51. PMID 15956344 DOI: 10.1677/Jme.1.01812 |
0.344 |
|
| 2005 |
Pan H, Nanno D, Che FY, Zhu X, Salton SR, Steiner DF, Fricker LD, Devi LA. Neuropeptide processing profile in mice lacking prohormone convertase-1. Biochemistry. 44: 4939-48. PMID 15779921 DOI: 10.1021/Bi047852M |
0.369 |
|
| 2005 |
Dey A, Lipkind GM, Rouillé Y, Norrbom C, Stein J, Zhang C, Carroll R, Steiner DF. Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon. Endocrinology. 146: 713-27. PMID 15528303 DOI: 10.1210/En.2004-1118 |
0.311 |
|
| 2004 |
Henquin JC, Boitard C, Cerasi E, Ferrannini E, Steiner DF, Efendic S. Impact of treatment on islet function in type 2 diabetes. Diabetes. 53: S1-5. PMID 15561896 DOI: 10.2337/Diabetes.53.Suppl_3.S1 |
0.382 |
|
| 2004 |
Steiner DF. The proinsulin C-peptide--a multirole model. Experimental Diabesity Research. 5: 7-14. PMID 15198367 DOI: 10.1080/15438600490424389 |
0.521 |
|
| 2004 |
Ma L, Bindokas VP, Kuznetsov A, Rhodes C, Hays L, Edwardson JM, Ueda K, Steiner DF, Philipson LH. Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proceedings of the National Academy of Sciences of the United States of America. 101: 9266-71. PMID 15197259 DOI: 10.1073/Pnas.0403201101 |
0.37 |
|
| 2004 |
Webb GC, Dey A, Wang J, Stein J, Milewski M, Steiner DF. Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets. The Journal of Biological Chemistry. 279: 31068-75. PMID 15143067 DOI: 10.1074/Jbc.M404110200 |
0.342 |
|
| 2004 |
Boitard C, Cerasi E, Efendic S, Henquin JC, Steiner DF, Ferrannini E. Novel factors in the regulation of beta-cell function. Diabetes. 53: S1-3. PMID 14749258 DOI: 10.2337/Diabetes.53.2007.S1 |
0.384 |
|
| 2004 |
Marzban L, Trigo-Gonzalez G, Zhu X, Rhodes CJ, Halban PA, Steiner DF, Verchere CB. Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide. Diabetes. 53: 141-8. PMID 14693708 DOI: 10.2337/Diabetes.53.1.141 |
0.365 |
|
| 2004 |
Dey A, Norrbom C, Zhu X, Stein J, Zhang C, Ueda K, Steiner DF. Furin and prohormone convertase 1/3 are major convertases in the processing of mouse pro-growth hormone-releasing hormone. Endocrinology. 145: 1961-71. PMID 14684599 DOI: 10.1210/En.2003-1472 |
0.327 |
|
| 2004 |
Ugleholdt R, Zhu X, Deacon CF, Ørskov C, Steiner DF, Holst JJ. Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1. Endocrinology. 145: 1349-55. PMID 14630721 DOI: 10.1210/En.2003-0801 |
0.369 |
|
| 2003 |
Wang J, Webb G, Cao Y, Steiner DF. Contrasting patterns of expression of transcription factors in pancreatic alpha and beta cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 12660-5. PMID 14557546 DOI: 10.1073/Pnas.1735286100 |
0.327 |
|
| 2003 |
Vincent M, Guz Y, Rozenberg M, Webb G, Furuta M, Steiner D, Teitelman G. Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased α-cell proliferation, and islet neogenesis Endocrinology. 144: 4061-4069. PMID 12933680 DOI: 10.1210/En.2003-0088 |
0.373 |
|
| 2003 |
Wang J, Cao Y, Steiner DF. Regulation of proglucagon transcription by activated transcription factor (ATF) 3 and a novel isoform, ATF3b, through the cAMP-response element/ATF site of the proglucagon gene promoter. The Journal of Biological Chemistry. 278: 32899-904. PMID 12815047 DOI: 10.1074/Jbc.M305456200 |
0.363 |
|
| 2003 |
Lilla V, Webb G, Rickenbach K, Maturana A, Steiner DF, Halban PA, Irminger JC. Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. Endocrinology. 144: 1368-79. PMID 12639920 DOI: 10.1210/En.2002-220916 |
0.415 |
|
| 2002 |
Efendic S, Boitard C, Cerasi E, Ferrannini E, Henquin JC, Steiner DF. Regulation of insulin production: In search of therapeutic targets Diabetes. 51: S285-S287. PMID 12475764 DOI: 10.2337/Diabetes.51.2007.S285 |
0.41 |
|
| 2002 |
Westermark GT, Falkmer S, Steiner DF, Chan SJ, Engström U, Westermark P. Islet amyloid polypeptide is expressed in the pancreatic islet parenchyma of the teleostean fish, Myoxocephalus (cottus) scorpius. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 133: 119-25. PMID 12223219 DOI: 10.1016/S1096-4959(02)00113-6 |
0.455 |
|
| 2002 |
Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, Zhang C, Laurent V, Lindberg I, Ugleholdt R, Holst JJ, Steiner DF. Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proceedings of the National Academy of Sciences of the United States of America. 99: 10293-8. PMID 12145326 DOI: 10.1073/Pnas.162352599 |
0.406 |
|
| 2002 |
Zhu X, Orci L, Carroll R, Norrbom C, Ravazzola M, Steiner DF. Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. Proceedings of the National Academy of Sciences of the United States of America. 99: 10299-304. PMID 12136131 DOI: 10.1073/Pnas.162352799 |
0.475 |
|
| 2002 |
Laurent V, Kimble A, Peng B, Zhu P, Pintar JE, Steiner DF, Lindberg I. Mortality in 7B2 null mice can be rescued by adrenalectomy: involvement of dopamine in ACTH hypersecretion. Proceedings of the National Academy of Sciences of the United States of America. 99: 3087-92. PMID 11854475 DOI: 10.1073/Pnas.261715099 |
0.308 |
|
| 2002 |
Henquin JC, Boitard C, Efendic S, Ferrannini E, Steiner DF, Cerasi E. Insulin secretion: movement at all levels. Diabetes. 51: S1-2. PMID 11815449 DOI: 10.2337/Diabetes.51.2007.S1 |
0.445 |
|
| 2002 |
Webb GC, Akbar MS, Zhao C, Swift HH, Steiner DF. Glucagon replacement via micro-osmotic pump corrects hypoglycemia and alpha-cell hyperplasia in prohormone convertase 2 knockout mice. Diabetes. 51: 398-405. PMID 11812747 DOI: 10.2337/Diabetes.51.2.398 |
0.378 |
|
| 2001 |
Furuta M, Zhou A, Webb G, Carroll R, Ravazzola M, Orci L, Steiner DF. Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice. The Journal of Biological Chemistry. 276: 27197-202. PMID 11356850 DOI: 10.1074/Jbc.M103362200 |
0.409 |
|
| 2001 |
Webb GC, Akbar MS, Zhao C, Steiner DF. Expression profiling of pancreatic beta-cells: glucose regulation of secretory and metabolic pathway genes. Diabetes. 50: S135-6. PMID 11272173 DOI: 10.2337/Diabetes.50.2007.S135 |
0.322 |
|
| 2001 |
Wang J, Xu J, Finnerty J, Furuta M, Steiner DF, Verchere CB. The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site. Diabetes. 50: 534-9. PMID 11246872 DOI: 10.2337/Diabetes.50.3.534 |
0.38 |
|
| 2000 |
Westermark GT, Gebre-Medhin S, Steiner DF, Westermark P. Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP. Molecular Medicine (Cambridge, Mass.). 6: 998-1007. PMID 11474116 DOI: 10.1007/Bf03402051 |
0.31 |
|
| 2000 |
Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, Thinakaran G, Lynn DG, Meredith SC, Sisodia SS. Familial British dementia: expression and metabolism of BRI. Annals of the New York Academy of Sciences. 920: 93-9. PMID 11193182 DOI: 10.1111/J.1749-6632.2000.Tb06909.X |
0.371 |
|
| 2000 |
Nakagawa SH, Tager HS, Steiner DF. Mutational analysis of invariant valine B12 in insulin: implications for receptor binding. Biochemistry. 39: 15826-35. PMID 11123908 DOI: 10.1021/Bi001802+ |
0.657 |
|
| 2000 |
Westermark GT, Steiner DF, Gebre-Medhin S, Engström U, Westermark P. Pro islet amyloid polypeptide (ProIAPP) immunoreactivity in the islets of Langerhans. Upsala Journal of Medical Sciences. 105: 97-106. PMID 11095107 DOI: 10.1517/03009734000000057 |
0.35 |
|
| 2000 |
Bass J, Turck C, Rouard M, Steiner DF. Furin-mediated processing in the early secretory pathway: sequential cleavage and degradation of misfolded insulin receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 11905-9. PMID 11050224 DOI: 10.1073/Pnas.97.22.11905 |
0.406 |
|
| 2000 |
Webb GC, Akbar MS, Zhao C, Steiner DF. Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 5773-8. PMID 10811900 DOI: 10.1073/Pnas.100126597 |
0.388 |
|
| 2000 |
Oliva AA, Chan SJ, Steiner DF. Evolution of the prohormone convertases: identification of a homologue of PC6 in the protochordate amphioxus. Biochimica Et Biophysica Acta. 1477: 338-48. PMID 10708868 DOI: 10.1016/S0167-4838(99)00283-6 |
0.31 |
|
| 2000 |
Jin Chan S, Steiner DF. Insulin Through the Ages: Phylogeny of a Growth Promoting and Metabolic Regulatory Hormone American Zoologist. 40: 213-222. DOI: 10.1668/0003-1569(2000)040[0213:Ittapo]2.0.Co;2 |
0.485 |
|
| 1999 |
Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, Lynn DG, Thinakaran G, Meredith SC, Sisodia SS. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nature Neuroscience. 2: 984-8. PMID 10526337 DOI: 10.1038/14783 |
0.36 |
|
| 1999 |
Furukawa H, Carroll RJ, Swift HH, Steiner DF. Long-term elevation of free fatty acids leads to delayed processing of proinsulin and prohormone convertases 2 and 3 in the pancreatic beta-cell line MIN6. Diabetes. 48: 1395-401. PMID 10389844 DOI: 10.2337/Diabetes.48.7.1395 |
0.403 |
|
| 1999 |
Rouard M, Bass J, Grigorescu F, Garrett TP, Ward CW, Lipkind G, Jaffiole C, Steiner DF, Bell GI. Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain. The Journal of Biological Chemistry. 274: 18487-91. PMID 10373457 DOI: 10.1074/Jbc.274.26.18487 |
0.374 |
|
| 1999 |
Westphal CH, Muller L, Zhou A, Zhu X, Bonner-Weir S, Schambelan M, Steiner DF, Lindberg I, Leder P. The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease. Cell. 96: 689-700. PMID 10089884 DOI: 10.1016/S0092-8674(00)80579-6 |
0.349 |
|
| 1999 |
Viale A, Ortola C, Hervieu G, Furuta M, Barbero P, Steiner DF, Seidah NG, Nahon JL. Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals. The Journal of Biological Chemistry. 274: 6536-45. PMID 10037747 DOI: 10.1074/Jbc.274.10.6536 |
0.343 |
|
| 1999 |
Lipkind G, Steiner DF. Predicted structural alterations in proinsulin during its interactions with prohormone convertases. Biochemistry. 38: 890-6. PMID 9893983 DOI: 10.1021/Bi981556Q |
0.409 |
|
| 1998 |
Johanning K, Juliano MA, Juliano L, Lazure C, Lamango NS, Steiner DF, Lindberg I. Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates. The Journal of Biological Chemistry. 273: 22672-80. PMID 9712897 DOI: 10.1074/Jbc.273.35.22672 |
0.343 |
|
| 1998 |
Steiner DF. The proprotein convertases. Current Opinion in Chemical Biology. 2: 31-9. PMID 9667917 DOI: 10.1016/S1367-5931(98)80033-1 |
0.35 |
|
| 1998 |
Duguay SJ, Jin Y, Stein J, Duguay AN, Gardner P, Steiner DF. Post-translational processing of the insulin-like growth factor-2 precursor. Analysis of O-glycosylation and endoproteolysis. The Journal of Biological Chemistry. 273: 18443-51. PMID 9660813 DOI: 10.1074/Jbc.273.29.18443 |
0.464 |
|
| 1998 |
Bass J, Chiu G, Argon Y, Steiner DF. Folding of insulin receptor monomers is facilitated by the molecular chaperones calnexin and calreticulin and impaired by rapid dimerization. The Journal of Cell Biology. 141: 637-46. PMID 9566965 DOI: 10.1083/Jcb.141.3.637 |
0.394 |
|
| 1998 |
Milewski WM, Duguay SJ, Chan SJ, Steiner DF. Conservation of PDX-1 structure, function, and expression in zebrafish. Endocrinology. 139: 1440-9. PMID 9492081 DOI: 10.1210/Endo.139.3.5768 |
0.438 |
|
| 1998 |
Furuta M, Carroll R, Martin S, Swift HH, Ravazzola M, Orci L, Steiner DF. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2. The Journal of Biological Chemistry. 273: 3431-7. PMID 9452465 DOI: 10.1074/Jbc.273.6.3431 |
0.479 |
|
| 1997 |
Chan SJ, Plisetskaya EM, Urbinati E, Jin Y, Steiner DF. Expression of multiple insulin and insulin-like growth factor receptor genes in salmon gill cartilage. Proceedings of the National Academy of Sciences of the United States of America. 94: 12446-51. PMID 9356469 DOI: 10.1073/Pnas.94.23.12446 |
0.454 |
|
| 1997 |
Varlamov O, Fricker LD, Furukawa H, Steiner DF, Langley SH, Leiter EH. β-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing Endocrinology. 138: 4883-4892. PMID 9348219 DOI: 10.1210/Endo.138.11.5506 |
0.36 |
|
| 1997 |
Steiner DF, Rubenstein AH. Proinsulin C-peptide-biological activity? Science. 277: 531-532. PMID 9254422 DOI: 10.1126/Science.277.5325.531 |
0.432 |
|
| 1997 |
Furuta M, Yano H, Zhou A, Rouillé Y, Holst JJ, Carroll R, Ravazzola M, Orci L, Furuta H, Steiner DF. Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2 Proceedings of the National Academy of Sciences of the United States of America. 94: 6646-6651. PMID 9192619 DOI: 10.1073/Pnas.94.13.6646 |
0.388 |
|
| 1997 |
Kaiser N, Bailyes EM, Schneider BS, Cerasi E, Steiner DF, Hutton JC, Gross DJ. Characterization of the unusual insulin of Psammomys obesus, a rodent with nutrition-induced NIDDM-like syndrome. Diabetes. 46: 953-7. PMID 9166665 DOI: 10.2337/Diab.46.6.953 |
0.499 |
|
| 1997 |
Kristensen C, Kjeldsen T, Wiberg FC, Schäffer L, Hach M, Havelund S, Bass J, Steiner DF, Andersen AS. Alanine scanning mutagenesis of insulin Journal of Biological Chemistry. 272: 12978-12983. PMID 9148904 DOI: 10.1074/Jbc.272.20.12978 |
0.354 |
|
| 1997 |
Pittman I, Nakagawa SH, Tager HS, Steiner DF. Maintenance of the B-chain beta-turn in [GlyB24] insulin mutants: a steady-state fluorescence anisotropy study. Biochemistry. 36: 3430-7. PMID 9131992 DOI: 10.1021/Bi9624144 |
0.64 |
|
| 1997 |
Duguay SJ, Milewski WM, Young BD, Nakayama K, Steiner DF. Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases Journal of Biological Chemistry. 272: 6663-6670. PMID 9045697 DOI: 10.1074/Jbc.272.10.6663 |
0.384 |
|
| 1997 |
Upton Z, Francis GL, Chan SJ, Steiner DF, Wallace JC, Ballard FJ. Evolution of insulin-like growth factor (IGF) function: Production and characterization of recombinant hagfish IGF General and Comparative Endocrinology. 105: 79-90. PMID 9000470 DOI: 10.1006/Gcen.1996.6802 |
0.411 |
|
| 1996 |
Duguay SJ, Lai-Zhang J, Steiner DF, Funkenstein B, Chan SJ. Developmental and tissue-regulated expression of IGF-I and IGF-II mRNAs in sparus aurata Journal of Molecular Endocrinology. 16: 123-132. PMID 9156515 DOI: 10.1677/Jme.0.0160123 |
0.326 |
|
| 1996 |
Pashmforoush M, Chan SJ, Steiner DF. Structure and expression of the insulin-like peptide receptor from amphioxus Molecular Endocrinology. 10: 857-866. PMID 8813726 DOI: 10.1210/Mend.10.7.8813726 |
0.468 |
|
| 1996 |
Steiner DF, Rouillé Y, Gong Q, Martin S, Carroll R, Chan SJ. The role of prohormone convertases in insulin biosynthesis : Evidence for inherited defects in their action in man and experimental animals Diabetes and Metabolism. 22: 94-104. PMID 8792089 |
0.429 |
|
| 1996 |
Bass J, Kurose T, Pashmforoush M, Steiner DF. Fusion of insulin receptor ectodomains to immunoglobulin constant domains reproduces high-affinity insulin binding in vitro Journal of Biological Chemistry. 271: 19367-19375. PMID 8702623 DOI: 10.1074/Jbc.271.32.19367 |
0.407 |
|
| 1996 |
Zhu X, Rouille Y, Lamango NS, Steiner DF, Lindberg I. Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: A potential mechanism for its inactivation Proceedings of the National Academy of Sciences of the United States of America. 93: 4919-4924. PMID 8643504 DOI: 10.1073/Pnas.93.10.4919 |
0.35 |
|
| 1996 |
Westermark P, Li ZC, Westermark GT, Leckström A, Steiner DF. Effects of beta cell granule components on human islet amyloid polypeptide fibril formation. Febs Letters. 379: 203-6. PMID 8603689 DOI: 10.1016/0014-5793(95)01512-4 |
0.376 |
|
| 1995 |
Rouillé Y, Duguay SJ, Lund K, Furuta M, Gong Q, Lipkind G, Oliva AA, Chan SJ, Steiner DF. Proteolytic Processing Mechanisms in the Biosynthesis of Neuroendocrine Peptides: The Subtilisin-like Proprotein Convertases Frontiers in Neuroendocrinology. 16: 322-361. PMID 8557169 DOI: 10.1006/Frne.1995.1012 |
0.349 |
|
| 1995 |
Westermark G, Arora MB, Fox N, Carroll R, Chan SJ, Westermark P, Steiner DF. Amyloid formation in response to beta cell stress occurs in vitro, but not in vivo, in islets of transgenic mice expressing human islet amyloid polypeptide. Molecular Medicine (Cambridge, Mass.). 1: 542-53. PMID 8529120 DOI: 10.1007/Bf03401591 |
0.309 |
|
| 1995 |
Lipkind G, Gong Q, Steiner DF. Molecular modeling of the substrate specificity of prohormone convertases SPC2 and SPC3 Journal of Biological Chemistry. 270: 13277-13284. PMID 7768927 DOI: 10.1074/Jbc.270.22.13277 |
0.339 |
|
| 1995 |
Oliva AA, Steiner DF, Shu Jin Chan. Proprotein convertases in amphioxus: Predicted structure and expression of proteases SPC2 and SPC3 Proceedings of the National Academy of Sciences of the United States of America. 92: 3591-3595. PMID 7724604 DOI: 10.1073/Pnas.92.8.3591 |
0.404 |
|
| 1995 |
Naggert JK, Fricker LD, Varlamov O, Nishina PM, Rouille Y, Steiner DF, Carroll RJ, Paigen BJ, Leiter EH. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity Nature Genetics. 10: 135-142. PMID 7663508 DOI: 10.1038/Ng0695-135 |
0.304 |
|
| 1995 |
German M, Ashcroft S, Docherty K, Edlund H, Edlund T, Goodison S, Imura H, Kennedy G, Madsen O, Melloul D, Moss L, Olson K, Permutt MA, Philippe J, Robertson RP, ... ... Steiner D, et al. The insulin gene promoter: A simplified nomenclature Diabetes. 44: 1002-1004. PMID 7621988 DOI: 10.2337/diab.44.8.1002 |
0.315 |
|
| 1995 |
Duguay SJ, Lai-Zhang J, Steiner DF. Mutational analysis of the insulin-like growth factor I prohormone processing site Journal of Biological Chemistry. 270: 17566-17574. PMID 7615562 DOI: 10.1074/Jbc.270.29.17566 |
0.396 |
|
| 1995 |
Vincent MT, Carroll RJ, Hammer RE, Chan SJ, Guz Y, Steiner DF, Teitelman G. A transgene coding for a human insulin analog has a mitogenic effect on murine embryonic β cells Proceedings of the National Academy of Sciences of the United States of America. 92: 6239-6243. PMID 7603977 DOI: 10.1073/Pnas.92.14.6239 |
0.444 |
|
| 1995 |
Rouille Y, Martin S, Steiner DF. Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide Journal of Biological Chemistry. 270: 26488-26496. PMID 7592866 DOI: 10.1074/Jbc.270.44.26488 |
0.395 |
|
| 1995 |
Dai G, Smeekens SP, Steiner DF, McMurtry JP, Kwok SC. Characterization of multiple prohormone convertase PC1/3 transcripts in porcine ovary. Biochimica Et Biophysica Acta. 1264: 1-6. PMID 7578241 DOI: 10.1016/0167-4781(95)00111-S |
0.32 |
|
| 1995 |
Duguay SJ, Chan SJ, Mommsen TP, Steiner DF. Divergence of insulin-like growth factors I and II in the elasmobranch, Squalus acanthias. Febs Letters. 371: 69-72. PMID 7545136 DOI: 10.1016/0014-5793(95)00879-E |
0.376 |
|
| 1994 |
Rouillé Y, Westermark G, Martin SK, Steiner DF. Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 3242-6. PMID 8159732 DOI: 10.1073/Pnas.91.8.3242 |
0.342 |
|
| 1994 |
Zigman JM, Westermark GT, LaMendola J, Steiner DF. Expression of cone transducin, Gz alpha, and other G-protein alpha-subunit messenger ribonucleic acids in pancreatic islets. Endocrinology. 135: 31-7. PMID 8013366 DOI: 10.1210/Endo.135.1.8013366 |
0.525 |
|
| 1994 |
Kurose T, Pashmforoush M, Yoshimasa Y, Carroll R, Schwartz GP, Burke GT, Katsoyannis PG, Steiner DF. Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the α-subunit of the insulin receptor. Identification of a new insulin-binding domain in the insulin receptor Journal of Biological Chemistry. 269: 29190-29197. PMID 7961885 |
0.377 |
|
| 1994 |
Fan L, Westermark G, Chan SJ, Steiner DF. Altered gene structure and tissue expression of islet amyloid polypeptide in the chicken Molecular Endocrinology. 8: 713-721. PMID 7935487 DOI: 10.1210/Mend.8.6.7935487 |
0.401 |
|
| 1994 |
Hanabusa T, Ohagi S, LaMendola J, Chan SJ, Steiner DF. Nucleotide sequence and analysis of the mouse SPC3 promoter region Febs Letters. 356: 339-341. PMID 7805868 DOI: 10.1016/0014-5793(94)01285-7 |
0.34 |
|
| 1994 |
Martin SK, Carroll R, Benig M, Steiner DF. Regulation by glucose of the biosynthesis of PC2, PC3 and proinsulin in (ob/ob) mouse islets of Langerhans. Febs Letters. 356: 279-82. PMID 7805854 DOI: 10.1016/0014-5793(94)01284-9 |
0.39 |
|
| 1994 |
Pashmforoush M, Yoshimasa Y, Steiner DF. Exon 11 enhances insulin binding affinity and tyrosine kinase activity of the human insulin proreceptor Journal of Biological Chemistry. 269: 32639-32648. PMID 7798270 |
0.38 |
|
| 1994 |
Chu YC, Thompson Burke G, Gammeltoft S, Chan SJ, Steiner DF, Katsoyannis PG. High-potency hybrid compounds related to insulin and amphioxus insulin-like peptide Biochemistry. 33: 13087-13092. DOI: 10.1021/Bi00248A018 |
0.455 |
|
| 1994 |
Chan SJ, Steiner DF. 7 Structure and Expression of Insulinlike Growth Factor Genes in Fish Fish Physiology. 13: 213-224. DOI: 10.1016/S1546-5098(08)60068-0 |
0.48 |
|
| 1993 |
Fox N, Schrementi J, Nishi M, Ohagi S, Chan SJ, Heisserman JA, Westermark GT, Leckström A, Westermark P, Steiner DF. Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM). Febs Letters. 323: 40-4. PMID 8495745 DOI: 10.1016/0014-5793(93)81444-5 |
0.417 |
|
| 1993 |
Gong Q, Shu Jin Chan, Bajkowski AS, Steiner DF, Frankfater A. Characterization of the cathepsin B gene and multiple mRNAs in human tissues: Evidence for alternative splicing of cathepsin B pre-mRNA Dna and Cell Biology. 12: 299-309. PMID 8494608 DOI: 10.1089/Dna.1993.12.299 |
0.317 |
|
| 1993 |
Fan L, Gardner P, Shu Jin Chan, Steiner DF. Cloning and analysis of the gene encoding hummingbird proinsulin General and Comparative Endocrinology. 91: 25-30. PMID 8405887 DOI: 10.1006/Gcen.1993.1100 |
0.42 |
|
| 1993 |
Madsen OD, Karlsen C, Nielsen E, Lund K, Kofod H, Welinder B, Rehfeld JF, Larsson LI, Steiner DF, Holst JJ, Michelsen BK. The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable α- and β-cell tumor phenotypes Endocrinology. 133: 2022-2030. PMID 8404649 DOI: 10.1210/Endo.133.5.8404649 |
0.35 |
|
| 1993 |
Kavsan VM, Koval AP, Grebenjuk VA, Chan SJ, Steiner DF, Roberts CT, LeRoith D. Structure of the chum salmon insulin-like growth factor I gene Dna and Cell Biology. 12: 729-737. PMID 8397830 DOI: 10.1089/Dna.1993.12.729 |
0.44 |
|
| 1993 |
Zigman JM, Westermark GT, LaMendola J, Boel E, Steiner DF. Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system. Endocrinology. 133: 2508-14. PMID 8243272 DOI: 10.1210/Endo.133.6.8243272 |
0.575 |
|
| 1993 |
Herold KC, Nagamatsu S, Buse JB, Kulsakdinun P, Steiner DF. Inhibition of glucose-stimulated insulin release from βTC3 cells and rodent islets by an analog of FK506 Transplantation. 55: 186-192. PMID 7678356 DOI: 10.1097/00007890-199301000-00035 |
0.462 |
|
| 1992 |
Nagamatsu S, Steiner DF. Altered glucose regulation of insulin biosynthesis in insulinoma cells: Mouse βTC3 cells secrete insulin-related peptides predominantly via a constitutive pathway Endocrinology. 130: 748-754. PMID 1733723 DOI: 10.1210/en.130.2.748 |
0.362 |
|
| 1992 |
Bailyes EM, Shennan IJ, Seal AJ, Smeekens SP, Steiner DF, Hutton JC, Docherty K. A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase Biochemical Journal. 285: 391-394. PMID 1637332 DOI: 10.1042/Bj2850391 |
0.356 |
|
| 1992 |
Ohagi S, LaMendola J, LeBeau MM, Espinosa R, Takeda J, Smeekens SP, Chan SJ, Steiner DF. Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues Proceedings of the National Academy of Sciences of the United States of America. 89: 4977-4981. PMID 1594602 DOI: 10.1073/Pnas.89.11.4977 |
0.347 |
|
| 1992 |
Nagamatsu S, Nishi M, Steiner DF. Effects of islet amyloid polypeptide (IAPP) on insulin biosynthesis or secretion in rat islets and mouse βTC3 cells. Biosynthesis of IAPP in mouse βTC3 cells Diabetes Research and Clinical Practice. 15: 49-55. PMID 1541235 DOI: 10.1016/0168-8227(92)90067-2 |
0.455 |
|
| 1992 |
Shu Jin Chan, Oliva AA, LaMendola J, Grens A, Bode H, Steiner DF. Conservation of the prohormone convertase gene family in metazoa: Analysis of cDNAs encoding a PC3-like protein from hydra Proceedings of the National Academy of Sciences of the United States of America. 89: 6678-6682. PMID 1495957 DOI: 10.1073/Pnas.89.15.6678 |
0.339 |
|
| 1992 |
Steiner DF, James DE. Cellular and molecular biology of the Beta cell Diabetologia. 35: S41-S48. PMID 1478377 DOI: 10.1007/Bf00586278 |
0.461 |
|
| 1992 |
Nishi M, Sanke T, Ohagi S, Ekawa K, Wakasaki H, Nanjo K, Bell GI, Steiner dF. Molecular biology of islet amyloid polypeptide Diabetes Research and Clinical Practice. 15: 37-44. PMID 1371737 DOI: 10.1016/0168-8227(92)90065-Y |
0.404 |
|
| 1992 |
Smeekens SP, Chan SJ, Steiner DF. The biosynthesis and processing of neuroendocrine peptides: Identification of proprotein convertases involved in intravesicular processing Progress in Brain Research. 92: 235-246. PMID 1302878 DOI: 10.1016/S0079-6123(08)61179-6 |
0.413 |
|
| 1992 |
Chan SJ, Nagamatsu S, Cao QP, Steiner DF. Structure and evolution of insulin and insulin-like growth factors in chordates Progress in Brain Research. 92: 15-24. PMID 1302874 DOI: 10.1016/S0079-6123(08)61161-9 |
0.496 |
|
| 1991 |
Shennan KIJ, Smeekens SP, Steiner DF, Docherty K. Characterization of PC2, a mammalian Kex2 homologue, following expression of the cDNA in microinjected Xenopus oocytes Febs Letters. 284: 277-280. PMID 2060650 DOI: 10.1016/0014-5793(91)80703-6 |
0.358 |
|
| 1991 |
Steiner DF, Ohagi S, Nagamatsu S, Bell GI, Nishi M. Is islet amyloid polypeptide a significant factor in pathogenesis or pathophysiology of diabetes? Diabetes. 40: 305-309. PMID 1999269 DOI: 10.2337/Diab.40.3.305 |
0.351 |
|
| 1991 |
Smeekens SP, Avruch AS, LaMendola J, Chan SJ, Steiner DF. Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans Proceedings of the National Academy of Sciences of the United States of America. 88: 340-344. PMID 1988934 DOI: 10.1073/Pnas.88.2.340 |
0.386 |
|
| 1991 |
Philipson LH, Hice RE, Schaefer K, Lamendola J, Bell GI, Nelson DJ, Steiner DF. Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel Proceedings of the National Academy of Sciences of the United States of America. 88: 53-57. PMID 1986382 DOI: 10.1073/Pnas.88.1.53 |
0.316 |
|
| 1991 |
Nagamatsu S, Nishi M, Steiner DF. Biosynthesis of islet amyloid polypeptide: Elevated expression in mouse βTC3 cells Journal of Biological Chemistry. 266: 13737-13741. PMID 1856207 |
0.319 |
|
| 1991 |
Madsen OD, Nielsen JH, Michelsen B, Westermark P, Betsholtz C, Nishi M, Steiner DF. Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cells. Molecular Endocrinology (Baltimore, Md.). 5: 143-8. PMID 1850107 DOI: 10.1210/Mend-5-1-143 |
0.487 |
|
| 1991 |
Ohagi S, Nishi M, Bell GI, Ensinck JW, Steiner DF. Sequences of islet amyloid polypeptide precursors of an old world monkey, the pig-tailed macaque (Macaca nemestrina), and the dog (Canis familiaris) Diabetologia. 34: 555-558. PMID 1718805 DOI: 10.1007/Bf00400272 |
0.393 |
|
| 1990 |
Cao QP, Duguay SJ, Plisetskaya E, Steiner DF, Chan SJ. Nucleotide sequence and growth hormone-regulated expression of salmon insulin-like growth factor I mRNA. Molecular Endocrinology (Baltimore, Md.). 3: 2005-10. PMID 2628735 DOI: 10.1210/Mend-3-12-2005 |
0.389 |
|
| 1990 |
Nishi M, Sanke T, Seino S, Eddy RL, Fan YS, Byers MG, Shows TB, Bell GI, Steiner DF. Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history. Molecular Endocrinology (Baltimore, Md.). 3: 1775-81. PMID 2608057 DOI: 10.1210/Mend-3-11-1775 |
0.367 |
|
| 1990 |
Nishi M, Steiner DF. Cloning of complementary DNAs encoding islet amyloid polypeptide, insulin, and glucagon precursors from a new world rodent, the degu, Octodon degus Molecular Endocrinology. 4: 1192-1198. PMID 2293024 DOI: 10.1210/Mend-4-8-1192 |
0.479 |
|
| 1990 |
Nishi M, Bell GI, Steiner DF. Islet amyloid polypeptide (amylin): no evidence of an abnormal precursor sequence in 25 Type 2 (non-insulin-dependent) diabetic patients Diabetologia. 33: 628-630. PMID 2258001 DOI: 10.1007/Bf00400208 |
0.376 |
|
| 1990 |
Nishi M, Bell GI, Steiner DF. Sequence of a cDNA encoding Syrian hamster islet amyloid polypeptide precursor Nucleic Acids Research. 18: 6726. PMID 2251153 DOI: 10.1093/Nar/18.22.6726 |
0.323 |
|
| 1990 |
Yoshimasa Y, Paul JI, Whittaker J, Steiner DF. Effects of amino acid replacements within the tetrabasic cleavage site on the processing of the human insulin receptor precursor expressed in Chinese hamster ovary cells Journal of Biological Chemistry. 265: 17230-17237. PMID 2211623 |
0.343 |
|
| 1990 |
Steiner DF, Tager HS, Chan SJ, Nanjo K, Sanke T, Rubenstein AH. Lessons learned from molecular biology of insulin-gene mutations. Diabetes Care. 13: 600-9. PMID 2192846 DOI: 10.2337/Diacare.13.6.600 |
0.685 |
|
| 1990 |
Nagamatsu S, Carroll RJ, Grodsky GM, Steiner DF. Lack of islet amyloid polypeptide regulation of insulin biosynthesis or secretion in normal rat islets Diabetes. 39: 871-874. PMID 2191889 DOI: 10.2337/Diab.39.7.871 |
0.463 |
|
| 1990 |
Ohagi S, Nishi M, Steiner DF. Sequence of a cDNA encoding human LRP (leukocyte common antigen-related peptide) Nucleic Acids Research. 18: 7159. PMID 2175890 DOI: 10.1093/Nar/18.23.7159 |
0.344 |
|
| 1990 |
Nishi M, Ohagi S, Steiner DF. Novel putative protein tyrosine phosphatases identified by the polymerase chain reaction Febs Letters. 271: 178-180. PMID 2171999 DOI: 10.1016/0014-5793(90)80400-D |
0.312 |
|
| 1990 |
Shu Jin Chan, Cao QP, Steiner DF. Evolution of the insulin superfamily: Cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus Proceedings of the National Academy of Sciences of the United States of America. 87: 9319-9323. PMID 1701257 DOI: 10.1073/Pnas.87.23.9319 |
0.509 |
|
| 1990 |
Madsen OD, Christina Andersen L, Michelsen B, Lernmark Å, Steiner DF. Tissue-specific expression of transfected human insulin genes in pluripotent clonal rat insulinoma lines induced during passage in vivo Journal of Autoimmunity. 3: 76-77. DOI: 10.1016/0896-8411(90)90072-Z |
0.395 |
|
| 1989 |
Nishi M, Chan SJ, Nagamatsu S, Bell GI, Steiner DF. Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone. Proceedings of the National Academy of Sciences of the United States of America. 86: 5738-42. PMID 2668946 DOI: 10.1073/Pnas.86.15.5738 |
0.41 |
|
| 1989 |
STEINER DF, CHAN SJ, SMEEKENS SP, BELL GI, EMDIN S, FALKMER S. Evolution of Peptide Hormones of the Islets of Langerhans and of Mechanisms of Proteolytic Processing The Biological Bulletin. 177: 172-175. DOI: 10.2307/1541927 |
0.335 |
|
| 1988 |
Miyano M, Nanjo K, Chan SJ, Sanke T, Kondo M, Steiner DF. Use of in vitro DNA amplification to screen family members for an insulin gene mutation. Diabetes. 37: 862-6. PMID 3290004 DOI: 10.2337/Diab.37.7.862 |
0.445 |
|
| 1988 |
Yoshimasa Y, Seino S, Whittaker J, Kakehi T, Kosaki A, Kuzuya H, Imura H, Bell GI, Steiner DF. Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing. Science (New York, N.Y.). 240: 784-7. PMID 3283938 DOI: 10.1126/Science.3283938 |
0.489 |
|
| 1988 |
Carroll RJ, Hammer RE, Chan SJ, Swift HH, Rubenstein AH, Steiner DF. A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway. Proceedings of the National Academy of Sciences of the United States of America. 85: 8943-7. PMID 3057496 DOI: 10.1073/Pnas.85.23.8943 |
0.371 |
|
| 1988 |
Steiner DF, Chan SJ. An overview of insulin evolution. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 20: 443-4. PMID 3049292 DOI: 10.1055/s-2007-1010855 |
0.346 |
|
| 1988 |
Madsen OD, Andersen LC, Michelsen B, Owerbach D, Larsson LI, Lernmark A, Steiner DF. Tissue-specific expression of transfected human insulin genes in pluripotent clonal rat insulinoma lines induced during passage in vivo. Proceedings of the National Academy of Sciences of the United States of America. 85: 6652-6. PMID 2842785 DOI: 10.1073/Pnas.85.18.6652 |
0.5 |
|
| 1988 |
Welsh M, Welsh N, Nilsson T, Arkhammar P, Pepinsky RB, Steiner DF, Berggren PO. Stimulation of pancreatic islet beta-cell replication by oncogenes. Proceedings of the National Academy of Sciences of the United States of America. 85: 116-20. PMID 2829167 DOI: 10.1073/Pnas.85.1.116 |
0.356 |
|
| 1988 |
Seino S, Blackstone CD, Chan SJ, Whittaker J, Bell GI, Steiner DF. Appalachian spring: variations on ancient gastro-entero-pancreatic themes in New World mammals. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 20: 430-5. PMID 2459041 DOI: 10.1055/S-2007-1010853 |
0.453 |
|
| 1987 |
Nanjo K, Miyano M, Kondo M, Sanke T, Nishimura S, Miyamura K, Inouye K, Given BD, Chan SJ, Polonsky KS, Tager HS, Steiner DF, Rubenstein AH. Insulin Wakayama: familial mutant insulin syndrome in Japan Diabetologia. 30: 87-92. PMID 3552828 DOI: 10.1007/Bf00274577 |
0.696 |
|
| 1987 |
Chan SJ, Seino S, Gruppuso PA, Schwartz R, Steiner DF. A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia Proceedings of the National Academy of Sciences of the United States of America. 84: 2194-2197. PMID 3470784 DOI: 10.1073/Pnas.84.8.2194 |
0.412 |
|
| 1987 |
Welsh N, Welsh M, Steiner DF, Hellerstrom C. Mechanisms of leucine- and theophylline-stimulated insulin biosynthesis in isolated rat pancreatic islets Biochemical Journal. 246: 245-248. PMID 3314866 DOI: 10.1042/bj2460245 |
0.343 |
|
| 1987 |
Sample CE, Steiner DF. Tissue-specific binding of a nuclear factor to the insulin gene promoter Febs Letters. 222: 332-336. PMID 3308516 DOI: 10.1016/0014-5793(87)80396-4 |
0.449 |
|
| 1987 |
Steiner DF, Michael J, Houghten R, Mathieu M, Gardner PR, Ravazzola M, Orci L. Use of a synthetic peptide antigen to generate antisera reactive with a proteolytic processing site in native human proinsulin: demonstration of cleavage within clathrin-coated (pro)secretory vesicles. Proceedings of the National Academy of Sciences of the United States of America. 84: 6184-8. PMID 3306670 DOI: 10.1073/Pnas.84.17.6184 |
0.428 |
|
| 1987 |
Whittaker J, Okamoto AK, Thys R, Bell GI, Steiner DF, Hofmann CA. High-level expression of human insulin receptor cDNA in mouse NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 5237-41. PMID 3299382 DOI: 10.1073/Pnas.84.15.5237 |
0.435 |
|
| 1987 |
Seino S, Steiner DF, Bell GI. Sequence of a New World primate insulin having low biological potency and immunoreactivity. Proceedings of the National Academy of Sciences of the United States of America. 84: 7423-7. PMID 3118367 DOI: 10.1073/Pnas.84.21.7423 |
0.481 |
|
| 1987 |
Madsen OD, Larsson LI, Rehfeld JF, Schwartz TW, Lernmark A, Labrecque AD, Steiner DF. Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones. The Journal of Cell Biology. 103: 2025-34. PMID 2877997 DOI: 10.1083/Jcb.103.5.2025 |
0.377 |
|
| 1986 |
Seino S, Welsh M, Bell GI, Chan SJ, Steiner DF. Mutations in the guinea pig preproglucagon gene are restricted to a specific portion of the prohormone sequence. Febs Letters. 203: 25-30. PMID 3755107 DOI: 10.1016/0014-5793(86)81429-6 |
0.369 |
|
| 1986 |
Steiner DF, Chan SJ, Welsh JM, Nielsen D, Michael J, Tager HS, Rubenstein AH. Models of peptide biosynthesis: the molecular and cellular basis of insulin production. Clinical and Investigative Medicine. Mã©Decine Clinique Et Experimentale. 9: 328-36. PMID 3542328 |
0.642 |
|
| 1986 |
Chan SJ, San Segundo B, McCormick MB, Steiner DF. Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs. Proceedings of the National Academy of Sciences of the United States of America. 83: 7721-5. PMID 3463996 DOI: 10.1073/Pnas.83.20.7721 |
0.327 |
|
| 1986 |
Welsh M, Scherberg N, Gilmore R, Steiner DF. Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose. The Biochemical Journal. 235: 459-67. PMID 3017307 DOI: 10.1042/Bj2350459 |
0.449 |
|
| 1985 |
Steiner DF, Chan SJ, Welsh JM, Kwok SC. Structure and evolution of the insulin gene. Annual Review of Genetics. 19: 463-84. PMID 3909947 DOI: 10.1146/Annurev.Ge.19.120185.002335 |
0.433 |
|
| 1985 |
San Segundo B, Chan SJ, Steiner DF. Identification of cDNA clones encoding a precursor of rat liver cathepsin B. Proceedings of the National Academy of Sciences of the United States of America. 82: 2320-4. PMID 2986112 DOI: 10.1073/Pnas.82.8.2320 |
0.326 |
|
| 1984 |
Chan SJ, Episkopou V, Zeitlin S, Karathanasis SK, MacKrell A, Steiner DF, Efstratiadis A. Guinea pig preproinsulin gene: an evolutionary compromise? Proceedings of the National Academy of Sciences of the United States of America. 81: 5046-50. PMID 6591179 DOI: 10.1073/Pnas.81.16.5046 |
0.311 |
|
| 1984 |
Naithani VK, Steffens GJ, Tager HS, Buse G, Rubenstein AH, Steiner DF. Isolation and amino-acid sequence determination of monkey insulin and proinsulin. Hoppe-Seyler's Zeitschrift Fã¼R Physiologische Chemie. 365: 571-5. PMID 6381277 DOI: 10.1515/Bchm2.1984.365.1.571 |
0.679 |
|
| 1984 |
Steiner DF, Docherty K, Carroll R. Golgi/granule processing of peptide hormone and neuropeptide precursors: a minireview. Journal of Cellular Biochemistry. 24: 121-30. PMID 6373800 DOI: 10.1002/Jcb.240240204 |
0.411 |
|
| 1984 |
Madsen OD, Frank BH, Steiner DF. Human proinsulin-specific antigenic determinants identified by monoclonal antibodies. Diabetes. 33: 1012-6. PMID 6207064 DOI: 10.2337/Diab.33.10.1012 |
0.413 |
|
| 1983 |
Marsh JW, Nahum A, Steiner DF. Reductive methylation of insulin. Production of a biologically active tritiated insulin. International Journal of Peptide and Protein Research. 22: 39-49. PMID 6411646 DOI: 10.1111/J.1399-3011.1983.Tb02066.X |
0.444 |
|
| 1983 |
Docherty K, Carroll R, Steiner DF. Identification of a 31,500 molecular weight islet cell protease as cathepsin B. Proceedings of the National Academy of Sciences of the United States of America. 80: 3245-9. PMID 6344078 DOI: 10.1073/Pnas.80.11.3245 |
0.378 |
|
| 1983 |
Shoelson S, Haneda M, Blix P, Nanjo A, Sanke T, Inouye K, Steiner D, Rubenstein A, Tager H. Three mutant insulins in man Nature. 302: 540-543. PMID 6339950 DOI: 10.1038/302540A0 |
0.755 |
|
| 1983 |
Kwok SC, Steiner DF, Rubenstein AH, Tager HS. Identification of a point mutation in the human insulin gene giving rise to a structurally abnormal insulin (insulin Chicago). Diabetes. 32: 872-5. PMID 6313457 DOI: 10.2337/Diab.32.9.872 |
0.684 |
|
| 1983 |
Haneda M, Chan SJ, Kwok SC, Rubenstein AH, Steiner DF. Studies on mutant human insulin genes: identification and sequence analysis of a gene encoding [SerB24]insulin. Proceedings of the National Academy of Sciences of the United States of America. 80: 6366-70. PMID 6312455 DOI: 10.1073/Pnas.80.20.6366 |
0.451 |
|
| 1983 |
Nielsen DA, Chou J, MacKrell AJ, Casadaban MJ, Steiner DF. Expression of a preproinsulin-beta-galactosidase gene fusion in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 80: 5198-202. PMID 6310564 DOI: 10.1073/Pnas.80.17.5198 |
0.561 |
|
| 1983 |
Madsen OD, Cohen RM, Fitch FW, Rubenstein AH, Steiner DF. The production and characterization of monoclonal antibodies specific for human proinsulin using a sensitive microdot assay procedure. Endocrinology. 113: 2135-44. PMID 6196183 DOI: 10.1210/Endo-113-6-2135 |
0.348 |
|
| 1983 |
Docherty K, Hutton J, Steiner D. Enzymes involved in the conversion of proinsulin to insulin Regulatory Peptides. 7: 283. DOI: 10.1016/0167-0115(83)90047-2 |
0.432 |
|
| 1982 |
Chan SJ, Weiss J, Konrad M, White T, Bahl C, Yu SD, Marks D, Steiner DF. Biosynthesis and periplasmic segregation of human proinsulin in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 78: 5401-5. PMID 7029534 DOI: 10.1073/pnas.78.9.5401 |
0.368 |
|
| 1982 |
Docherty K, Carroll RJ, Steiner DF. Conversion of proinsulin to insulin: involvement of a 31,500 molecular weight thiol protease Proceedings of the National Academy of Sciences of the United States of America. 79: 4613-4617. PMID 6750605 DOI: 10.1073/Pnas.79.15.4613 |
0.346 |
|
| 1982 |
Nielsen DA, Lernmark A, Berelowitz M, Bloom GD, Steiner DF. Sorting of pancreatic islet cell subpopulations by light scattering using a fluorescence-activated cell sorter. Diabetes. 31: 299-306. PMID 6130019 DOI: 10.2337/Diab.31.4.299 |
0.564 |
|
| 1981 |
Tager HS, Steiner DF, Patzelt C. Biosynthesis of insulin and glucagon. Methods in Cell Biology. 23: 73-88. PMID 7035811 DOI: 10.1016/S0091-679X(08)61492-2 |
0.716 |
|
| 1981 |
Baekkeskov S, Kanatsuna T, Klareskog L, Nielsen DA, Peterson PA, Rubenstein AH, Steiner DF, Lernmark A. Expression of major histocompatibility antigens on pancreatic islet cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 6456-60. PMID 7031653 DOI: 10.1073/Pnas.78.10.6456 |
0.589 |
|
| 1981 |
Hofmann C, Ji TH, Miller B, Steiner DF. Photoaffinity labeling of the insulin receptor in H4 hepatoma cells: lack of cellular receptor processing. Journal of Supramolecular Structure and Cellular Biochemistry. 15: 1-13. PMID 7019574 DOI: 10.1002/Jsscb.1981.380150102 |
0.452 |
|
| 1981 |
Kanatsuna T, Lernmark A, Rubenstein AH, Steiner DF. Block in insulin release from column-perifused pancreatic β-cells induced by islet cell surface antibodies and complement Diabetes. 30: 231-234. PMID 7009272 DOI: 10.2337/Diab.30.3.231 |
0.401 |
|
| 1981 |
Chan SJ, Kwok SC, Steiner DF. The biosynthesis of insulin: some genetic and evolutionary aspects. Diabetes Care. 4: 4-10. PMID 7009112 DOI: 10.2337/Diacare.4.1.4 |
0.41 |
|
| 1981 |
Emdin SO, Steiner DF. A specific antiserum against insulin from the Atlantic hagfish, Myxine glutinosa: characterization of the antiserum, its use in a homologous radioimmunoassay, and immunofluorescent microscopy. General and Comparative Endocrinology. 42: 251-8. PMID 7002712 DOI: 10.1016/0016-6480(80)90195-1 |
0.468 |
|
| 1981 |
Hofmann C, Marsh JW, Miller B, Steiner DF. Cultured hepatoma cells as a model system for studying insulin processing and biologic responsiveness. Diabetes. 29: 865-74. PMID 7000584 DOI: 10.2337/Diab.29.11.865 |
0.48 |
|
| 1981 |
Kwok SC, Chan SJ, Rubenstein AH, Poucher R, Steiner DF. Loss of a restriction endonuclease cleavage site in the gene of a structurally abnormal human insulin. Biochemical and Biophysical Research Communications. 98: 844-9. PMID 6261753 DOI: 10.1016/0006-291X(81)91188-8 |
0.474 |
|
| 1980 |
Lernmark A, Kanatsuna T, Patzelt C, Diakoumis K, Carroll R, Rubenstein AH, Steiner DF. Antibodies directed against the pancreatic islet cell plasma membrane detection and specificity Diabetologia. 19: 445-451. PMID 7004963 DOI: 10.1007/Bf00281824 |
0.358 |
|
| 1980 |
Steiner DF, Quinn PS, Chan SJ, Marsh J, Tager HS. Processing mechanisms in the biosynthesis of proteins. Annals of the New York Academy of Sciences. 343: 1-16. PMID 6994549 DOI: 10.1111/J.1749-6632.1980.Tb47238.X |
0.621 |
|
| 1980 |
Patzelt C, Tager HS, Carroll RJ, Steiner DF. Identification of prosomatostatin in pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America. 77: 2410-4. PMID 6771754 DOI: 10.1073/Pnas.77.5.2410 |
0.667 |
|
| 1980 |
Pilkis SJ, El-Maghrabi MR, Coven B, Claus TH, Tager HS, Steiner DF, Keim PS, Heinrikson RL. Phosphorylation of rat hepatic fructose-1,6-bisphosphatase and pyruvate kinase. The Journal of Biological Chemistry. 255: 2770-5. PMID 6244292 |
0.542 |
|
| 1980 |
Patzelt C, Neilsen D, Carroll R, Quinn P, Lernmark A, Tager HS, Steiner DF. Studies on the biosynthesis of the other peptide hormones of the rat islets of Langerhans. Biochemical Society Transactions. 8: 411-3. PMID 6108881 DOI: 10.1042/Bst0080411 |
0.625 |
|
| 1980 |
Steiner DF, Patzelt C, Chan SJ, Quinn PS, Tager HS, Nielsen D, Lernmark A, Noyes BE, Agarwal KL, Gabbay KH, Rubenstein AH. Formation of biologically active peptides. Proceedings of the Royal Society of London. Series B, Biological Sciences. 210: 45-59. PMID 6107930 DOI: 10.1098/Rspb.1980.0117 |
0.751 |
|
| 1980 |
Tager HS, Patzelt C, Assoian RK, Chan SJ, Duguid JR, Steiner DF. Biosynthesis of islet cell hormones. Annals of the New York Academy of Sciences. 343: 133-47. PMID 6104939 DOI: 10.1111/J.1749-6632.1980.Tb47247.X |
0.607 |
|
| 1979 |
Terris S, Hofmann C, Steiner DF. Mode of uptake and degradation of 125I-labelled insulin by isolated hepatocytes and H4 hepatoma cells. Canadian Journal of Biochemistry. 57: 459-68. PMID 476501 DOI: 10.1139/O79-059 |
0.458 |
|
| 1979 |
Chan SJ, Noyes BE, Agarwal KL, Steiner DF. Construction and selection of recombinant plasmids containing full-length complementary DNAs corresponding to rat insulins I and II. Proceedings of the National Academy of Sciences of the United States of America. 76: 5036-40. PMID 388427 DOI: 10.1073/Pnas.76.10.5036 |
0.404 |
|
| 1979 |
Patzelt C, Tager HS, Carroll RJ, Steiner DF. Identification and processing of proglucagon in pancreatic islets. Nature. 282: 260-6. PMID 388230 DOI: 10.1038/282260A0 |
0.64 |
|
| 1979 |
Lernmark A, Kanatsuna T, Rubenstein AH, Steiner DF. Detection and possible functional influence of antibodies directed againt the pancreatic islet cell surface Advances in Experimental Medicine and Biology. 119: 157-163. PMID 91312 DOI: 10.1007/978-1-4615-9110-8_23 |
0.387 |
|
| 1978 |
Kuzuya H, Chance RE, Steiner DF, Rubenstein AH. On the preparation and characterization of standard materials for natural human proinsulin and C-peptide Diabetes. 27: 161-169. PMID 631438 DOI: 10.2337/Diab.27.1.S161 |
0.381 |
|
| 1978 |
Wood SP, Tickle IJ, Blundell TL, Wollmer A, Steiner DF. Insulin polymorphism: some physical and biological properties of rat insulins. Archives of Biochemistry and Biophysics. 186: 175-83. PMID 564664 DOI: 10.1016/0003-9861(78)90477-0 |
0.332 |
|
| 1978 |
Lernmark A, Freedman ZR, Hofmann C, Rubenstein AH, Steiner DF, Jackson RL, Winter RJ, Traisman HS. Islet-cell-surface antibodies in juvenile diabetes mellitus New England Journal of Medicine. 299: 375-380. PMID 353557 DOI: 10.1056/Nejm197808242990802 |
0.349 |
|
| 1978 |
Steiner DF. On the role of the proinsulin C-peptide. Diabetes. 145-8. PMID 344111 DOI: 10.2337/Diab.27.1.S145 |
0.421 |
|
| 1978 |
Steiner DF, Chan SJ, Terris S, Hofmann C. Insulin as a cellular growth regulator. Ciba Foundation Symposium. 217-28. PMID 248001 DOI: 10.1002/9780470720363.ch11 |
0.383 |
|
| 1978 |
Patzelt C, Labrecque AD, Duguid JR, Carroll RJ, Keim PS, Heinrikson RL, Steiner DF. Detection and kinetic behavior of preproinsulin in pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America. 75: 1260-4. PMID 206890 DOI: 10.1073/Pnas.75.3.1260 |
0.422 |
|
| 1978 |
Horwitz DL, Rubenstein AH, Steiner DF. Proinsulin and C-peptide in diabetes Medical Clinics of North America. 62: 723-733. PMID 98676 DOI: 10.1016/S0025-7125(16)31768-0 |
0.397 |
|
| 1978 |
Kuzuya H, Blix PM, Horwitz DL, Rubenstein AH, Steiner DF, Faber OK, Binder C. Heterogeneity of circulating human C-peptide Diabetes. 27: 184-191. PMID 75814 DOI: 10.2337/Diab.27.1.S184 |
0.345 |
|
| 1978 |
Lernmark A, Nielsen DA, Steiner DF. Cation-dependent phosphatase activites in a rat pancreatic islet plasma membrane fraction prepared by one-step gradient centrifugation. Journal of Supramolecular Structure. 9: 327-36. PMID 34753 DOI: 10.1002/Jss.400090304 |
0.528 |
|
| 1977 |
Kuzuya H, Blix PM, Horwitz DL, Steiner DF, Rubenstein AH. Determination of free and total insulin and C-peptide in insulin-treated diabetics. Diabetes. 26: 22-9. PMID 830562 DOI: 10.2337/Diab.26.1.22 |
0.496 |
|
| 1977 |
Kuzuya H, Blix PM, Horwitz DL, Rubenstein AH, Steiner DF, Binder C, Faber OK. Heterogeneity of circulating C-peptide. The Journal of Clinical Endocrinology and Metabolism. 44: 952-62. PMID 558224 DOI: 10.1210/Jcem-44-5-952 |
0.345 |
|
| 1977 |
Rubenstein AH, Steiner DF, Horwitz DL, Mako ME, Block MB, Starr JI, Kuzuya H, Melani F. Clinical significance of circulating proinsulin and C-peptide. Recent Progress in Hormone Research. 33: 435-75. PMID 198859 DOI: 10.1016/B978-0-12-571133-3.50017-9 |
0.527 |
|
| 1977 |
Chan SJ, Steiner DF. Preproinsulin, a new precursor in insulin biosynthesis Trends in Biochemical Sciences. 2: 254-256. DOI: 10.1016/0968-0004(77)90217-1 |
0.474 |
|
| 1976 |
Steiner DF. Editorial: Errors in insulin biosynthesis. The New England Journal of Medicine. 294: 952-3. PMID 1256488 DOI: 10.1056/Nejm197604222941713 |
0.454 |
|
| 1976 |
Lernmark A, Chan SJ, Choy R, Nathans A, Carroll R, Tager HS, Rubenstein AH, Swift HH, Steiner DF. Biosynthesis of insulin and glucagon: a view of the current state of the art. Ciba Foundation Symposium. 41: 7-30. PMID 780079 |
0.687 |
|
| 1976 |
Shu Jin Chan, Keim P, Steiner DF. Cell free synthesis of rat preproinsulins: Characterization and partial amino acid sequence determination Proceedings of the National Academy of Sciences of the United States of America. 73: 1964-1968. PMID 778852 DOI: 10.1073/Pnas.73.6.1964 |
0.346 |
|
| 1976 |
Terris S, Steiner DF. Retention and degradation of 125I-insulin by perfused livers from diabetic rats. The Journal of Clinical Investigation. 57: 885-96. PMID 133120 DOI: 10.1172/Jci108365 |
0.475 |
|
| 1975 |
Kemmler W, Steiner DF. Fractionation of islet tissue in processing proinsulin to insulin. Methods in Enzymology. 31: 374-8. PMID 4371659 DOI: 10.1016/0076-6879(74)31041-5 |
0.438 |
|
| 1975 |
Yanaihara N, Sakura N, Yanaihara C, Hashimoto T, Rubenstein AH, Steiner DF. Syntheses and immunological evaluation of bovine proinsulin C-peptide analogues. Nature. 258: 365-366. PMID 1238906 DOI: 10.1038/258365A0 |
0.419 |
|
| 1975 |
Tager HS, Rubenstein AH, Steiner DF. Methods for the assessment of peptide precursors. Studies insulin biosynthesis. Methods in Enzymology. 37: 326-45. PMID 1092957 DOI: 10.1016/S0076-6879(75)37030-4 |
0.686 |
|
| 1975 |
Tager HS, Rubenstein AH, Steiner DF. [28] Methods for the assessment of peptide precursors. Studies on insulin biosynthesis Methods in Enzymology. 37: 326-345. DOI: 10.1016/S0076-6879(75)37030-4 |
0.648 |
|
| 1974 |
Steiner DF, Kemmler W, Tager HS, Rubenstein AH. Molecular events taking place during intracellular transport of exportable proteins. The conversion of peptide hormone precursors. Advances in Cytopharmacology. 2: 195-205. PMID 4613155 |
0.568 |
|
| 1974 |
Peterson JD, Coulter CL, Steiner DF, Emdin SO, Falkmer S. Structural and crystallographic observations on hagfish insulin Nature. 251: 239-240. PMID 4418746 DOI: 10.1038/251239A0 |
0.471 |
|
| 1974 |
Steiner DF, Kemmler W, Tager HS, Peterson JD. Proteolytic processing in the biosynthesis of insulin and other proteins. Federation Proceedings. 33: 2105-15. PMID 4370934 |
0.641 |
|
| 1974 |
Tager HS, Steiner DF. Peptide hormones. Annual Review of Biochemistry. 43: 509-38. PMID 4368999 DOI: 10.1146/annurev.bi.43.070174.002453 |
0.571 |
|
| 1974 |
Yanaihara N, Hashimoto T, Yanaihara C, Sakagami M, Steiner DF, Rubenstein AH. Synthesis of human connecting peptide derivatives and their immunological properties. Biochemical and Biophysical Research Communications. 59: 1124-1130. PMID 4213414 DOI: 10.1016/S0006-291X(74)80095-1 |
0.34 |
|
| 1973 |
Block MB, Rosenfield RL, Mako ME, Steiner DF, Rubenstein AH. Sequential changes in beta-cell function in insulin-treated diabetic patients assessed by C-peptide immunoreactivity. The New England Journal of Medicine. 288: 1144-8. PMID 4633551 DOI: 10.1056/Nejm197305312882202 |
0.463 |
|
| 1973 |
Tager HS, Emdin SO, Clark JL, Steiner DF. Studies on the conversion of proinsulin to insulin. II. Evidence for a chymotrypsin-like cleavage in the connecting peptide region of insulin precursors in the rat. The Journal of Biological Chemistry. 248: 3476-82. PMID 4573980 |
0.665 |
|
| 1973 |
Steiner DF. Cocrystallization of Proinsulin and Insulin Nature. 243: 528-530. PMID 4550045 DOI: 10.1038/243528A0 |
0.441 |
|
| 1973 |
Tager HS, Steiner DF. Isolation of a glucagon-containing peptide: primary structure of a possible fragment of proglucagon. Proceedings of the National Academy of Sciences of the United States of America. 70: 2321-5. PMID 4525166 DOI: 10.1073/Pnas.70.8.2321 |
0.626 |
|
| 1973 |
FALKMER S, EMDIN S, HAVU N, LUNDGREN G, MARQUES M, ÖSTBERG Y, STEINER DF, THOMAS NW. Insulin in Invertebrates and Cyclostomes American Zoologist. 13: 625-638. DOI: 10.1093/icb/13.3.625 |
0.353 |
|
| 1973 |
Steiner DF, Peterson JD, Tager H, Emdin S, Ostberg Y, Falkmer S. Comparative aspects of proinsulin and insulin structure and biosynthesis Integrative and Comparative Biology. 13: 591-604. DOI: 10.1093/Icb/13.3.591 |
0.692 |
|
| 1972 |
Rubenstein AH, Pottenger LA, Mako M, Getz GS, Steiner DF. The metabolism of proinsulin and insulin by the liver. The Journal of Clinical Investigation. 51: 912-21. PMID 5014618 DOI: 10.1172/Jci106886 |
0.466 |
|
| 1972 |
Tager HS, Steiner DF. Primary structures of the proinsulin connecting peptides of the rat and the horse. The Journal of Biological Chemistry. 247: 7936-40. PMID 4640931 |
0.555 |
|
| 1972 |
Kemmler W, Peterson JD, Rubenstein AH, Steiner DF. On the biosynthesis, intracellular transport and mechanism of conversion of proinsulin to insulin and C-peptide Diabetes. 21: 572-581. PMID 4626567 DOI: 10.2337/Diab.21.2.S572 |
0.515 |
|
| 1972 |
Block MB, Mako ME, Steiner DF, Rubenstein AH. Diabetic ketoacidosis: evidence for C-peptide and proinsulin secretion following recovery. The Journal of Clinical Endocrinology and Metabolism. 35: 402-6. PMID 4626271 DOI: 10.1210/Jcem-35-3-402 |
0.46 |
|
| 1972 |
Rubenstein AH, Block MB, Starr J, Melani F, Steiner DF. Proinsulin and C-peptide in blood. Diabetes. 21: 661-72. PMID 4341001 DOI: 10.2337/Diab.21.2.S661 |
0.502 |
|
| 1972 |
Sando H, Borg J, Steiner DF. Studies on the secretion of newly synthesized proinsulin and insulin from isolated rat islets of Langerhans. The Journal of Clinical Investigation. 51: 1476-85. PMID 4336941 DOI: 10.1172/JCI106944 |
0.341 |
|
| 1972 |
Block MB, Mako ME, Steiner DF, Rubenstein AH. Circulating C-peptide immunoreactivity. Studies in normals and diabetic patients. Diabetes. 21: 1013-26. PMID 4116300 DOI: 10.2337/Diab.21.10.1013 |
0.456 |
|
| 1971 |
Kemmler W, Steiner DF. Conversion of proinsulin to insulin in a subcellular fraction from rat islets. Biochemical and Biophysical Research Communications. 41: 1223-30. PMID 4921757 DOI: 10.1016/0006-291X(70)90217-2 |
0.421 |
|
| 1970 |
Melani F, Rubenstein AH, Steiner DF. Human serum proinsulin. The Journal of Clinical Investigation. 49: 497-507. PMID 5461203 DOI: 10.1172/Jci106259 |
0.447 |
|
| 1970 |
Melani F, Rubenstein AH, Oyer PE, Steiner DF. Identification of proinsulin and C-peptide in human serum by a specific immunoassay. Proceedings of the National Academy of Sciences of the United States of America. 67: 148-55. PMID 4318774 DOI: 10.1073/Pnas.67.1.148 |
0.452 |
|
| 1970 |
Melani F, Ryan WG, Rubenstein AH, Steiner DF. Proinsulin secretion by a pancreatic beta-cell adenoma. Proinsulin and C-peptide secretion. The New England Journal of Medicine. 283: 713-9. PMID 4318337 DOI: 10.1056/Nejm197010012831401 |
0.482 |
|
| 1970 |
Steiner DF, Clark JL, Nolan C, Rubenstein AH, Margoliash E, Aten B, Oyer PE. Proinsulin and the biosynthesis of insulin. Recent Progress in Hormone Research. 25: 207-82. PMID 4311938 DOI: 10.1016/b978-0-12-571125-8.50008-9 |
0.359 |
|
| 1970 |
Rubenstein AH, Steiner DF. Proinsulin: The Single Chain Precursor of Insulin Medical Clinics of North America. 54: 191-199. DOI: 10.1016/S0025-7125(16)32687-6 |
0.445 |
|
| 1969 |
Rubenstein AH, Steiner DF, Cho S, Lawrence AM, Kirsteins L. Immunological properties of bovine proinsulin and related fractions Diabetes. 18: 598-605. PMID 5821058 DOI: 10.2337/Diab.18.9.598 |
0.501 |
|
| 1969 |
Clark JL, Cho S, Rubenstein AH, Steiner DF. Isolation of a proinsulin connecting peptide fragment (C-peptide) from bovine and human pancreas. Biochemical and Biophysical Research Communications. 35: 456-61. PMID 5788502 DOI: 10.1016/0006-291X(69)90367-2 |
0.353 |
|
| 1969 |
Steiner DF, Hallund O, Rubenstein A, Cho S, Bayliss C. Isolation and properties of proinsulin, intermediate forms, and other minor components from crystalline bovine insulin. Diabetes. 17: 725-36. PMID 5726253 DOI: 10.2337/Diab.17.12.725 |
0.511 |
|
| 1969 |
Clark JL, Steiner DF. Insulin biosynthesis in the rat: demonstration of two proinsulins Proceedings of the National Academy of Sciences of the United States of America. 62: 278-285. PMID 4890253 DOI: 10.1073/Pnas.62.1.278 |
0.515 |
|
| 1969 |
Steiner DF. Proinsulin and the biosynthesis of insulin. The New England Journal of Medicine. 280: 1106-13. PMID 4305118 DOI: 10.1056/Nejm196905152802008 |
0.426 |
|
| 1969 |
Rubenstein AH, Clark JL, Melani F, Steiner DF. Secretion of proinsulin C-Peptide by pancreatic β cells and its circulation in blood Nature. 224: 697-699. DOI: 10.1038/224697A0 |
0.494 |
|
| 1968 |
Steiner DF. Evidence for a precursor in the biosynthesis of insulin. Transactions of the New York Academy of Sciences. 30: 60-8. PMID 4299035 DOI: 10.1111/J.2164-0947.1967.Tb02452.X |
0.469 |
|
| 1967 |
Steiner DF, King J. Insulin-stimulated ribonucleic acid synthesis and RNA polymerase activity in alloxan-diabetic rat liver. Biochimica Et Biophysica Acta. 119: 510-6. PMID 5963025 DOI: 10.1016/0005-2787(66)90127-4 |
0.412 |
|
| 1967 |
Steiner DF. Insulin and the regulation of hepatic biosynthetic activity. Vitamins and Hormones. 24: 1-61. PMID 5340862 DOI: 10.1016/S0083-6729(08)60202-2 |
0.378 |
|
| 1967 |
Steiner DF, Cunningham D, Spigelman L, Aten B. Insulin biosynthesis: evidence for a precursor. Science (New York, N.Y.). 157: 697-700. PMID 4291105 DOI: 10.1126/Science.157.3789.697 |
0.498 |
|
| 1956 |
Steiner DF, Anker HS. ON THE SYNTHESIS OF ANTIBODY PROTEIN IN VITRO. Proceedings of the National Academy of Sciences of the United States of America. 42: 580-6. PMID 16589910 DOI: 10.1073/Pnas.42.9.580 |
0.65 |
|
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