☰

Robert H. Singer - Publications

Affiliations: 
Albert Einstein College of Medicine, New York, New York, United States 
Area:
Cell Biology
Website:
http://www.singerlab.org
Tree Info Grants Similar researchers Related pubs Distance to... Nearest Nobel PubMed Report error

329 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Holland KL, Plutkis SE, Daugird TA, Sau A, Grimm JB, English BP, Zheng Q, Dave S, Rahman F, Xie L, Dong P, Tkachuk AN, Brown TA, Singer RH, Liu Z, et al. A series of spontaneously blinking dyes for super-resolution microscopy. Biorxiv : the Preprint Server For Biology. PMID 38766149 DOI: 10.1101/2024.02.23.581625  0.678
2024 Glauninger H, Bard JAM, Wong Hickernell CJ, Airoldi EM, Li W, Singer RH, Paul S, Fei J, Sosnick TR, Wallace EWJ, Drummond DA. Transcriptome-wide mRNA condensation precedes stress granule formation and excludes stress-induced transcripts. Biorxiv : the Preprint Server For Biology. PMID 38659805 DOI: 10.1101/2024.04.15.589678  0.648
2024 Maekiniemi A, Singer RH. RNA and Protein Detection by Single-Molecule Fluorescent in Situ Hybridization (smFISH) Combined with Immunofluorescence in the Budding Yeast S. cerevisiae. Methods in Molecular Biology (Clifton, N.J.). 2784: 45-58. PMID 38502477 DOI: 10.1007/978-1-0716-3766-1_3  0.414
2023 Kharod SC, Hwang D, Choi H, Yoon KJ, Castillo PE, Singer RH, Yoon YJ. Phosphorylation alters FMRP granules and determines their transport or protein synthesis abilities. Biorxiv : the Preprint Server For Biology. PMID 37781583 DOI: 10.1101/2023.03.15.532613  0.806
2023 Choi H, Liao YC, Yoon YJ, Grimm J, Lavis LD, Singer RH, Lippincott-Schwartz J. Lysosomal release of amino acids at ER three-way junctions regulates transmembrane and secretory protein mRNA translation. Biorxiv : the Preprint Server For Biology. PMID 37577585 DOI: 10.1101/2023.08.01.551382  0.385
2023 Roeder RG, Deibler SK, Jacobson A, Lillie JW, Rosbash M, Singer RH, Wajapeyee N. Michael R. Green (1954-2023). Molecular Cell. 83: 2152-2154. PMID 37419086 DOI: 10.1016/j.molcel.2023.06.027  0.349
2023 Roeder RG, Deibler SK, Jacobson A, Lillie JW, Rosbash M, Singer RH, Wajapeyee N. Michael R. Green (1954-2023). Cell. 186: 2722-2724. PMID 37352831 DOI: 10.1016/j.cell.2023.05.034  0.349
2023 Dasgupta S, Dayagi DY, Haimovich G, Wyler E, Olender T, Singer RH, Landthaler M, Gerst JE. Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture. Elife. 12. PMID 37249209 DOI: 10.7554/eLife.83584  0.332
2023 Birnbaum R, Biswas J, Singer RH, Sharp DJ. mRNA Localization and Local Translation of the Microtubule Severing Enzyme, Fidgetin-Like 2, in Polarization, Migration and Outgrowth. Biorxiv : the Preprint Server For Biology. PMID 37131812 DOI: 10.1101/2023.04.17.537087  0.39
2023 Das S, Lituma PJ, Castillo PE, Singer RH. Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation. Neuron. PMID 37100055 DOI: 10.1016/j.neuron.2023.04.005  0.518
2022 Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson SH, Murad R, Beall A, Colayco S, De-Jesus P, Chanda S, English BP, Singer RH, Jackson M, Topisirovic I, Ronai ZA. Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex. Frontiers in Pharmacology. 13: 1029093. PMID 36532738 DOI: 10.3389/fphar.2022.1029093  0.71
2022 Li W, Maekiniemi A, Sato H, Osman C, Singer RH. An improved imaging system that corrects MS2-induced RNA destabilization. Nature Methods. PMID 36357695 DOI: 10.1038/s41592-022-01658-1  0.666
2022 Gandin V, English BP, Freeman M, Leroux LP, Preibisch S, Walpita D, Jaramillo M, Singer RH. Cap-dependent translation initiation monitored in living cells. Nature Communications. 13: 6558. PMID 36323665 DOI: 10.1038/s41467-022-34052-8  0.764
2022 Lituma PJ, Singer RH, Das S, Castillo PE. Real-time imaging of transcription ex vivo reveals input-specific immediate early gene dynamics. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123373119. PMID 36095210 DOI: 10.1073/pnas.2123373119  0.458
2022 Núñez L, Buxbaum AR, Katz ZB, Lopez-Jones M, Nwokafor C, Czaplinski K, Pan F, Rosenberg J, Monday HR, Singer RH. Tagged actin mRNA dysregulation in IGF2BP1[Formula: see text] mice. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208465119. PMID 36067310 DOI: 10.1073/pnas.2208465119  0.848
2022 Monday HR, Kharod SC, Yoon YJ, Singer RH, Castillo PE. Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals. Neuron. PMID 35728596 DOI: 10.1016/j.neuron.2022.05.024  0.793
2022 Hwang JY, Monday HR, Yan J, Gompers A, Buxbaum AR, Sawicka KJ, Singer RH, Castillo PE, Zukin RS. CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X. Cell Reports. 39: 110853. PMID 35675768 DOI: 10.1016/j.celrep.2022.110853  0.804
2022 Li W, Singer RH. Detecting the Non-conventional mRNA Splicing and Translational Activation of HAC1 in Budding Yeast. Methods in Molecular Biology (Clifton, N.J.). 2378: 113-120. PMID 34985697 DOI: 10.1007/978-1-0716-1732-8_8  0.702
2021 Sato H, Singer RH. Cellular variability of nonsense-mediated mRNA decay. Nature Communications. 12: 7203. PMID 34893608 DOI: 10.1038/s41467-021-27423-0  0.417
2021 Xu W, Biswas J, Singer RH, Rosbash M. Targeted RNA editing: novel tools to study post-transcriptional regulation. Molecular Cell. PMID 34739873 DOI: 10.1016/j.molcel.2021.10.010  0.538
2021 Desai RV, Chen X, Martin B, Chaturvedi S, Hwang DW, Li W, Yu C, Ding S, Thomson M, Singer RH, Coleman RA, Hansen MMK, Weinberger LS. A DNA-repair pathway can affect transcriptional noise to promote cell fate transitions. Science (New York, N.Y.). PMID 34301855 DOI: 10.1126/science.abc6506  0.59
2021 Biswas J, Rosbash M, Singer RH, Rahman R. Protocol for using TRIBE to study RNA-protein interactions and nuclear organization in mammalian cells. Star Protocols. 2: 100634. PMID 34258595 DOI: 10.1016/j.xpro.2021.100634  0.646
2021 Biswas J, Li W, Singer RH, Coleman RA. Imaging Organization of RNA Processing within the Nucleus. Cold Spring Harbor Perspectives in Biology. PMID 34127450 DOI: 10.1101/cshperspect.a039453  0.642
2021 Das S, Vera M, Gandin V, Singer RH, Tutucci E. Author Correction: Intracellular mRNA transport and localized translation. Nature Reviews. Molecular Cell Biology. PMID 33911234 DOI: 10.1038/s41580-021-00374-6  0.775
2021 Das S, Vera M, Gandin V, Singer RH, Tutucci E. Intracellular mRNA transport and localized translation. Nature Reviews. Molecular Cell Biology. PMID 33837370 DOI: 10.1038/s41580-021-00356-8  0.825
2020 Tsuboi T, Viana MP, Xu F, Yu J, Chanchani R, Arceo XG, Tutucci E, Choi J, Chen YS, Singer RH, Rafelski SM, Zid BM. Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis. Elife. 9. PMID 32762840 DOI: 10.7554/Elife.57814  0.787
2020 Pichon X, Robert MC, Bertrand E, Singer RH, Tutucci E. New Generations of MS2 Variants and MCP Fusions to Detect Single mRNAs in Living Eukaryotic Cells. Methods in Molecular Biology (Clifton, N.J.). 2166: 121-144. PMID 32710406 DOI: 10.1007/978-1-0716-0712-1_7  0.813
2020 Tutucci E, Singer RH. Simultaneous Detection of mRNA and Protein in S. cerevisiae by Single-Molecule FISH and Immunofluorescence. Methods in Molecular Biology (Clifton, N.J.). 2166: 51-69. PMID 32710403 DOI: 10.1007/978-1-0716-0712-1_4  0.811
2020 Biswas J, Rahman R, Gupta V, Rosbash M, Singer RH. MS2-TRIBE Evaluates Both Protein-RNA Interactions and Nuclear Organization of Transcription by RNA Editing. Iscience. 23: 101318. PMID 32674054 DOI: 10.1016/J.Isci.2020.101318  0.747
2020 Wheat JC, Sella Y, Willcockson M, Skoultchi AI, Bergman A, Singer RH, Steidl U. Single-molecule imaging of transcription dynamics in somatic stem cells. Nature. PMID 32581360 DOI: 10.1038/S41586-020-2432-4  0.406
2020 Maekiniemi A, Singer RH, Tutucci E. Single molecule mRNA fluorescent hybridization combined with immunofluorescence in Dataset and quantification. Data in Brief. 30: 105511. PMID 32368581 DOI: 10.1016/J.Dib.2020.105511  0.81
2020 Sato H, Das S, Singer RH, Vera M. Imaging of DNA and RNA in Living Eukaryotic Cells to Reveal Spatiotemporal Dynamics of Gene Expression. Annual Review of Biochemistry. PMID 32176523 DOI: 10.1146/Annurev-Biochem-011520-104955  0.441
2020 Biswas J, Nunez L, Das S, Yoon YJ, Eliscovich C, Singer RH. Zipcode Binding Protein 1 (ZBP1; IGF2BP1): A Model for Sequence-Specific RNA Regulation. Cold Spring Harbor Symposia On Quantitative Biology. PMID 32086331 DOI: 10.1101/Sqb.2019.84.039396  0.715
2020 Tsuboi T, Viana MP, Xu F, Yu J, Chanchani R, Arceo XG, Tutucci E, Choi J, Chen YS, Singer RH, Rafelski SM, Zid BM. Author response: Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis Elife. DOI: 10.7554/Elife.57814.Sa2  0.76
2020 Moon HC, Das S, Singer RH, Yoon Park H. Real-Time Imaging of Transcription and Transport of Single Arc mRNA in Live Neurons Biophysical Journal. 118: 545a. DOI: 10.1016/J.Bpj.2019.11.2982  0.43
2019 Klein ME, Younts TJ, Cobo CF, Buxbaum AR, Aow J, Erdjument-Bromage H, Richard S, Malinow R, Neubert TA, Singer RH, Castillo PE, Jordan BA. Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons. Cell Reports. 29: 1789-1799.e6. PMID 31722197 DOI: 10.1016/J.Celrep.2019.10.030  0.814
2019 Biswas J, Patel VL, Bhaskar V, Chao JA, Singer RH, Eliscovich C. The structural basis for RNA selectivity by the IMP family of RNA-binding proteins. Nature Communications. 10: 4440. PMID 31570709 DOI: 10.1038/S41467-019-12193-7  0.693
2019 Liu LY, Long X, Yang CP, Miyares RL, Sugino K, Singer RH, Lee T. Mamo decodes hierarchical temporal gradients into terminal neuronal fate. Elife. 8. PMID 31545163 DOI: 10.7554/Elife.48056  0.377
2019 Vera M, Tutucci E, Singer RH. Imaging Single mRNA Molecules in Mammalian Cells Using an Optimized MS2-MCP System. Methods in Molecular Biology (Clifton, N.J.). 2038: 3-20. PMID 31407274 DOI: 10.1007/978-1-4939-9674-2_1  0.789
2019 Sato H, Wu B, Delahaye F, Singer RH, Greally JM. Retargeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains. The Journal of Cell Biology. PMID 31110057 DOI: 10.1083/Jcb.201811109  0.31
2019 Das S, Singer RH, Yoon YJ. The travels of mRNAs in neurons: do they know where they are going? Current Opinion in Neurobiology. 57: 110-116. PMID 30784978 DOI: 10.1016/J.Conb.2019.01.016  0.504
2019 Limi S, Zhao Y, Guo P, Lopez-Jones M, Zheng D, Singer RH, Skoultchi AI, Cvekl A. Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers. Investigative Ophthalmology & Visual Science. 60: 234-244. PMID 30646012 DOI: 10.1167/Iovs.18-25921  0.436
2018 Meissner GW, Nern A, Singer RH, Wong AM, Malkesman O, Long X. Mapping Neurotransmitter Identity in the Whole-Mount Brain Using Multiplex High-Throughput Fluorescence Hybridization. Genetics. PMID 30563859 DOI: 10.1534/Genetics.118.301749  0.356
2018 Tutucci E, Vera M, Singer RH. Single-mRNA detection in living S. cerevisiae using a re-engineered MS2 system. Nature Protocols. PMID 30218101 DOI: 10.1038/S41596-018-0037-2  0.802
2018 Biswas J, Liu Y, Singer RH, Wu B. Fluorescence Imaging Methods to Investigate Translation in Single Cells. Cold Spring Harbor Perspectives in Biology. PMID 30082468 DOI: 10.1101/Cshperspect.A032722  0.73
2018 Nwokafor C, Singer RH, Lim H. Imaging Cell-Type-Specific Dynamics of mRNAs in Living Mouse Brain. Methods (San Diego, Calif.). PMID 30067943 DOI: 10.1016/j.ymeth.2018.07.009  0.521
2018 Limi S, Senecal A, Coleman RA, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A. Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. The Journal of Biological Chemistry. PMID 29959226 DOI: 10.1074/Jbc.Ra118.001927  0.41
2018 Das S, Moon HC, Singer RH, Park HY. A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons. Science Advances. 4: eaar3448. PMID 29938222 DOI: 10.1126/Sciadv.Aar3448  0.586
2018 Zhou Y, Meng X, Chen S, Li W, Li D, Singer R, Gu W. IMP1 regulates UCA1-mediated cell invasion through facilitating UCA1 decay and decreasing the sponge effect of UCA1 for miR-122-5p. Breast Cancer Research : Bcr. 20: 32. PMID 29669595 DOI: 10.1186/s13058-018-0959-1  0.385
2018 Carvajal LA, Neriah DB, Senecal A, Benard L, Thiruthuvanathan V, Yatsenko T, Narayanagari SR, Wheat JC, Todorova TI, Mitchell K, Kenworthy C, Guerlavais V, Annis DA, Bartholdy B, Will B, ... ... Singer RH, et al. Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia. Science Translational Medicine. 10. PMID 29643228 DOI: 10.1126/Scitranslmed.Aao3003  0.308
2018 Tutucci E, Livingston NM, Singer RH, Wu B. Imaging mRNA In Vivo, from Birth to Death. Annual Review of Biophysics. PMID 29345990 DOI: 10.1146/Annurev-Biophys-070317-033037  0.822
2018 Kenworthy CA, Wong V, Dziuba P, Lavis LD, Liu W, Singer RH, Coleman RA. Single Molecule Imaging of Chromatin Remodeling in Live Cells Biophysical Journal. 114: 536a. DOI: 10.1016/J.Bpj.2017.11.2929  0.327
2017 Tutucci E, Vera M, Biswas J, Garcia J, Parker R, Singer RH. An improved MS2 system for accurate reporting of the mRNA life cycle. Nature Methods. PMID 29131164 DOI: 10.1038/Nmeth.4502  0.84
2017 Tsai A, Muthusamy AK, Alves MR, Lavis LD, Singer RH, Stern DL, Crocker J. Nuclear microenvironments modulate transcription from low-affinity enhancers. Elife. 6. PMID 29095143 DOI: 10.7554/Elife.28975  0.353
2017 Haimovich G, Ecker CM, Dunagin MC, Eggan E, Raj A, Gerst JE, Singer RH. Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078295 DOI: 10.1073/Pnas.1706365114  0.472
2017 Wang G, Zeng Y, Chen S, Li D, Li W, Zhou Y, Singer RH, Gu W. Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells. Scientific Reports. 7: 13575. PMID 29051606 DOI: 10.1038/s41598-017-14148-8  0.346
2017 Long X, Colonell J, Wong AM, Singer RH, Lionnet T. Quantitative mRNA imaging throughout the entire Drosophila brain. Nature Methods. PMID 28581495 DOI: 10.1038/Nmeth.4309  0.442
2017 Zhang Q, Meng X, Li D, Chen S, Luo J, Zhu L, Singer RH, Gu W. Binding of DEAD-box helicase Dhh1 to the 5'UTR of ASH1 mRNA represses localized translation of ASH1 in yeast cells. The Journal of Biological Chemistry. PMID 28450395 DOI: 10.1074/jbc.M117.776492  0.54
2017 Eliscovich C, Singer RH. RNP transport in cell biology: the long and winding road. Current Opinion in Cell Biology. 45: 38-46. PMID 28258033 DOI: 10.1016/j.ceb.2017.02.008  0.511
2017 Eliscovich C, Shenoy SM, Singer RH. Imaging mRNA and protein interactions within neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223507 DOI: 10.1073/pnas.1621440114  0.454
2017 lionnet t, Long X, Colonell J, Wong A, Singer R. Quantitative mRNA Imaging in Whole Mount Drosophila Brains Protocol Exchange. DOI: 10.1038/Protex.2017.051  0.373
2017 Zheng Q, Grimm JB, Muthusamy AK, Singer RH, Lavis LD. Bright and Photostable Fluorophores for Advanced Fluorescence Microscopy Biophysical Journal. 112: 21a. DOI: 10.1016/J.Bpj.2016.11.147  0.316
2017 Senecal A, Kenworthy C, Lavis L, Liu W, Singer RH, Coleman RA. Imaging Transcription Dynamics in Single Cancer Cells Biophysical Journal. 112: 211a. DOI: 10.1016/J.Bpj.2016.11.1166  0.396
2016 Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS. Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena(INV)-initiated invadopodium formation. Scientific Reports. 6: 37874. PMID 27901093 DOI: 10.1038/Srep37874  0.607
2016 Vera M, Biswas J, Senecal A, Singer RH, Park HY. Single-Cell and Single-Molecule Analysis of Gene Expression Regulation. Annual Review of Genetics. 50: 267-291. PMID 27893965 DOI: 10.1146/Annurev-Genet-120215-034854  0.739
2016 Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH. Glutamate-induced RNA localization and translation in neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791158 DOI: 10.1073/Pnas.1614267113  0.834
2016 Nwokafor CU, Sellers RS, Singer RH. IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model. Oncotarget. PMID 27655671 DOI: 10.18632/oncotarget.12083  0.364
2016 Brickner DG, Sood V, Tutucci E, Coukos R, Viets K, Singer R, Brickner JH. Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms. Molecular Biology of the Cell. PMID 27489341 DOI: 10.1091/Mbc.E16-03-0174  0.743
2016 Wu B, Eliscovich C, Yoon YJ, Singer RH. Translation dynamics of single mRNAs in live cells and neurons. Science (New York, N.Y.). 352: 1430-5. PMID 27313041 DOI: 10.1126/Science.Aaf1084  0.541
2016 Singer RH, Stoutenberg M, Gellman MD, Archer E, Davis SM, Gotman N, Marquez DX, Buelna C, Deng Y, Hosgood HD, Zambrana RE. Occupational Physical Activity and Body Mass Index: Results from the Hispanic Community Health Study / Study of Latinos. Plos One. 11: e0152339. PMID 27031996 DOI: 10.1371/Journal.Pone.0152339  0.398
2016 Wang G, Huang Z, Liu X, Huang W, Chen S, Zhou Y, Li D, Singer RH, Gu W. IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs. Oncotarget. PMID 26910917 DOI: 10.18632/oncotarget.7464  0.376
2016 Coleman RA, Liu Z, Darzacq X, Tjian R, Singer RH, Lionnet T. Imaging Transcription: Past, Present, and Future. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26763984 DOI: 10.1101/Sqb.2015.80.027201  0.668
2016 Katz ZB, English BP, Lionnet T, Yoon YJ, Monnier N, Ovryn B, Bathe M, Singer RH. Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes. Elife. 5. PMID 26760529 DOI: 10.7554/Elife.10415  0.854
2016 Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi S, Wang Y, Singer R, Hodgson L, Oktay M, Condeelis J. Abstract LB-006: Macrophage-dependent activation of Notch1 signaling regulates breast tumor cell intravasation Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-006  0.608
2016 Wu B, Eliscovich C, Yoon YJ, Singer RH. Translation dynamics of single mRNAs in live cells and neurons Science. 1-11. DOI: 10.1126/science.aaf1084  0.452
2016 Wu B, Miskolci V, Hodgson L, Singer RH. Synonymous Modification Enables High Fidelity Expression of Biosensors and Probes with Repetitive Protein and Nucleotide Sequences Biophysical Journal. 110: 335a. DOI: 10.1016/J.Bpj.2015.11.1802  0.408
2016 English BP, Singer RH. Simultaneous High-Speed Tracking of Multiple Single-Molecules Reveals Functional Interactions in Living Cells Biophysical Journal. 110: 15a. DOI: 10.1016/J.Bpj.2015.11.139  0.73
2015 English BP, Singer RH. A three-camera imaging microscope for high-speed single-molecule tracking and super-resolution imaging in living cells. Proceedings of Spie--the International Society For Optical Engineering. 9550: 955008. PMID 26819489 DOI: 10.1117/12.2190246  0.713
2015 LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. The Journal of Biological Chemistry. PMID 26475863 DOI: 10.1074/Jbc.M115.689604  0.303
2015 Deng W, Shi X, Tjian R, Lionnet T, Singer RH. CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 11870-5. PMID 26324940 DOI: 10.1073/Pnas.1515692112  0.336
2015 Monnier N, Barry Z, Park HY, Su KC, Katz Z, English BP, Dey A, Pan K, Cheeseman IM, Singer RH, Bathe M. Inferring transient particle transport dynamics in live cells. Nature Methods. 12: 838-40. PMID 26192083 DOI: 10.1038/Nmeth.3483  0.8
2015 Wu B, Buxbaum AR, Katz ZB, Yoon YJ, Singer RH. Quantifying Protein-mRNA Interactions in Single Live Cells. Cell. 162: 211-20. PMID 26140598 DOI: 10.1016/J.Cell.2015.05.054  0.851
2015 Buxbaum AR, Yoon YJ, Singer RH, Park HY. Single-molecule insights into mRNA dynamics in neurons. Trends in Cell Biology. 25: 468-75. PMID 26052005 DOI: 10.1016/J.Tcb.2015.05.005  0.832
2015 Hocine S, Vera M, Zenklusen D, Singer RH. Promoter-Autonomous Functioning in a Controlled Environment using Single Molecule FISH. Scientific Reports. 5: 9934. PMID 26017315 DOI: 10.1038/Srep09934  0.811
2015 Smith CS, Preibisch S, Joseph A, Abrahamsson S, Rieger B, Myers E, Singer RH, Grunwald D. Nuclear accessibility of β-actin mRNA is measured by 3D single-molecule real-time tracking. The Journal of Cell Biology. 209: 609-19. PMID 26008747 DOI: 10.1083/Jcb.201411032  0.462
2015 Wu B, Miskolci V, Sato H, Tutucci E, Kenworthy CA, Donnelly SK, Yoon YJ, Cox D, Singer RH, Hodgson L. Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences. Genes & Development. 29: 876-86. PMID 25877922 DOI: 10.1101/Gad.259358.115  0.781
2015 Kalo A, Kanter I, Shraga A, Sheinberger J, Tzemach H, Kinor N, Singer RH, Lionnet T, Shav-Tal Y. Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity. Cell Reports. 11: 419-32. PMID 25865891 DOI: 10.1016/j.celrep.2015.03.039  0.366
2015 Halstead JM, Lionnet T, Wilbertz JH, Wippich F, Ephrussi A, Singer RH, Chao JA. Translation. An RNA biosensor for imaging the first round of translation from single cells to living animals. Science (New York, N.Y.). 347: 1367-671. PMID 25792328 DOI: 10.1126/Science.Aaa3380  0.554
2015 Singer RH. Reminiscences on my life with RNA: a self-indulgent perspective. Rna (New York, N.Y.). 21: 508-9. PMID 25780116 DOI: 10.1261/rna.050922.115  0.547
2015 Campbell PD, Chao JA, Singer RH, Marlow FL. Dynamic visualization of transcription and RNA subcellular localization in zebrafish. Development (Cambridge, England). 142: 1368-74. PMID 25758462 DOI: 10.1242/Dev.118968  0.453
2015 Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH, Lionnet T, Lavis LD. A general method to improve fluorophores for live-cell and single-molecule microscopy. Nature Methods. 12: 244-50, 3 p followin. PMID 25599551 DOI: 10.1038/Nmeth.3256  0.702
2015 Song T, Zheng Y, Wang Y, Katz Z, Liu X, Chen S, Singer RH, Gu W. Specific interaction of KIF11 with ZBP1 regulates the transport of β-actin mRNA and cell motility. Journal of Cell Science. 128: 1001-10. PMID 25588836 DOI: 10.1242/Jcs.161679  0.772
2015 Buxbaum AR, Haimovich G, Singer RH. In the right place at the right time: visualizing and understanding mRNA localization. Nature Reviews. Molecular Cell Biology. 16: 95-109. PMID 25549890 DOI: 10.1038/Nrm3918  0.834
2015 Katz ZB, English BP, Lionnet T, Yoon YJ, Monnier N, Ovryn B, Bathe M, Singer RH. Author response: Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes Elife. DOI: 10.7554/Elife.10415.028  0.82
2015 Buxbaum AR, Haimovich G, Singer RH. Erratum: In the right place at the right time: visualizing and understanding mRNA localization Nature Reviews Molecular Cell Biology. 16: 513-513. DOI: 10.1038/Nrm4027  0.773
2015 Monnier N, Barry Z, Park HY, Su KC, Katz Z, English BP, Dey A, Pan K, Cheeseman IM, Singer RH, Bathe M. Inferring transient particle transport dynamics in live cells Nature Methods. DOI: 10.1038/nmeth.3483  0.8
2015 Barry Z, Monnier N, Park HY, Su K, Katz Z, English BP, Dey A, Pan K, Cheeseman IM, Singer RH, Bathe M. Bayesian Classification of Mrna and Kinetochore Transport Dynamics Biophysical Journal. 108: 164a-165a. DOI: 10.1016/J.Bpj.2014.11.907  0.814
2014 Piatkevich KD, English BP, Malashkevich VN, Xiao H, Almo SC, Singer RH, Verkhusha VV. Photoswitchable red fluorescent protein with a large Stokes shift. Chemistry & Biology. 21: 1402-14. PMID 25242289 DOI: 10.1016/J.Chembiol.2014.08.010  0.695
2014 Vera M, Pani B, Griffiths LA, Muchardt C, Abbott CM, Singer RH, Nudler E. The translation elongation factor eEF1A1 couples transcription to translation during heat shock response. Elife. 3: e03164. PMID 25233275 DOI: 10.7554/Elife.03164  0.453
2014 Vera M, Singer RH. Gene regulation: the HSP70 gene jumps when shocked. Current Biology : Cb. 24: R396-8. PMID 24845669 DOI: 10.1016/j.cub.2014.03.070  0.319
2014 Park HY, Lim H, Yoon YJ, Follenzi A, Nwokafor C, Lopez-Jones M, Meng X, Singer RH. Visualization of dynamics of single endogenous mRNA labeled in live mouse. Science (New York, N.Y.). 343: 422-4. PMID 24458643 DOI: 10.1126/Science.1239200  0.646
2014 Buxbaum AR, Wu B, Singer RH. Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (New York, N.Y.). 343: 419-22. PMID 24458642 DOI: 10.1126/Science.1242939  0.822
2014 Wu B, Chen J, Singer RH. Background free imaging of single mRNAs in live cells using split fluorescent proteins. Scientific Reports. 4: 3615. PMID 24402470 DOI: 10.1038/srep03615  0.49
2014 Fallini C, Rouanet JP, Donlin-Asp PG, Guo P, Zhang H, Singer RH, Rossoll W, Bassell GJ. Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons. Developmental Neurobiology. 74: 319-32. PMID 23897586 DOI: 10.1002/Dneu.22111  0.804
2014 Wu B, Yoon YJ, Singer RH. Visualization of Stimulation Dependent Localization of Single Endogenous mRNAs to Dendritic Spines Biophysical Journal. 106: 400a. DOI: 10.1016/J.Bpj.2013.11.2254  0.451
2013 Larson DR, Fritzsch C, Sun L, Meng X, Lawrence DS, Singer RH. Direct observation of frequency modulated transcription in single cells using light activation. Elife. 2: e00750. PMID 24069527 DOI: 10.7554/Elife.00750  0.325
2013 Coulon A, Chow CC, Singer RH, Larson DR. Eukaryotic transcriptional dynamics: from single molecules to cell populations. Nature Reviews. Genetics. 14: 572-84. PMID 23835438 DOI: 10.1038/Nrg3484  0.414
2013 Eliscovich C, Buxbaum AR, Katz ZB, Singer RH. mRNA on the move: the road to its biological destiny. The Journal of Biological Chemistry. 288: 20361-8. PMID 23720759 DOI: 10.1074/Jbc.R113.452094  0.852
2013 Newhart A, Rafalska-Metcalf IU, Yang T, Joo LM, Powers SL, Kossenkov AV, Lopez-Jones M, Singer RH, Showe LC, Skordalakes E, Janicki SM. Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site. The Journal of Biological Chemistry. 288: 19882-99. PMID 23689370 DOI: 10.1074/Jbc.M113.473181  0.343
2013 Chou YY, Heaton NS, Gao Q, Palese P, Singer RH, Singer R, Lionnet T. Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis. Plos Pathogens. 9: e1003358. PMID 23671419 DOI: 10.1371/Journal.Ppat.1003358  0.373
2013 Trcek T, Sato H, Singer RH, Maquat LE. Temporal and spatial characterization of nonsense-mediated mRNA decay. Genes & Development. 27: 541-51. PMID 23431032 DOI: 10.1101/Gad.209635.112  0.814
2013 Haimovich G, Choder M, Singer RH, Trcek T. The fate of the messenger is pre-determined: a new model for regulation of gene expression. Biochimica Et Biophysica Acta. 1829: 643-53. PMID 23337853 DOI: 10.1016/j.bbagrm.2013.01.004  0.807
2013 Hocine S, Raymond P, Zenklusen D, Chao JA, Singer RH. Single-molecule analysis of gene expression using two-color RNA labeling in live yeast. Nature Methods. 10: 119-21. PMID 23263691 DOI: 10.1038/Nmeth.2305  0.838
2013 Larson DR, Fritzsch C, Sun L, Meng X, Lawrence DS, Singer RH. Author response: Direct observation of frequency modulated transcription in single cells using light activation Elife. DOI: 10.7554/Elife.00750.024  0.311
2013 Singer R. Abstract SY29-03: Following single mRNAs from birth to death in living cells and tissues. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy29-03  0.543
2013 Coulon A, Ferguson ML, Palangat M, de Turris V, Singer RH, Chow CC, Larson DR. Direct Measurement of Initiation, Elongation, Splicing and Termination Kinetics in Living Human Cells Biophysical Journal. 104: 372a. DOI: 10.1016/J.Bpj.2012.11.2066  0.481
2012 Singer S, Zhao R, Barsotti AM, Ouwehand A, Fazollahi M, Coutavas E, Breuhahn K, Neumann O, Longerich T, Pusterla T, Powers MA, Giles KM, Leedman PJ, Hess J, Grunwald D, ... ... Singer RH, et al. Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Molecular Cell. 48: 799-810. PMID 23102701 DOI: 10.1016/J.Molcel.2012.09.020  0.368
2012 Chao JA, Yoon YJ, Singer RH. Imaging translation in single cells using fluorescent microscopy. Cold Spring Harbor Perspectives in Biology. 4. PMID 22960595 DOI: 10.1101/Cshperspect.A012310  0.504
2012 Katz ZB, Wells AL, Park HY, Wu B, Shenoy SM, Singer RH. β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration. Genes & Development. 26: 1885-90. PMID 22948660 DOI: 10.1101/Gad.190413.112  0.816
2012 Park HY, Trcek T, Wells AL, Chao JA, Singer RH. An unbiased analysis method to quantify mRNA localization reveals its correlation with cell motility. Cell Reports. 1: 179-84. PMID 22832165 DOI: 10.1016/J.Celrep.2011.12.009  0.834
2012 Wu B, Chao JA, Singer RH. Fluorescence fluctuation spectroscopy enables quantitative imaging of single mRNAs in living cells. Biophysical Journal. 102: 2936-44. PMID 22735544 DOI: 10.1016/J.Bpj.2012.05.017  0.518
2012 Lionnet T, Singer RH. Transcription goes digital. Embo Reports. 13: 313-21. PMID 22410830 DOI: 10.1038/embor.2012.31  0.414
2012 Trcek T, Chao JA, Larson DR, Park HY, Zenklusen D, Shenoy SM, Singer RH. Single-mRNA counting using fluorescent in situ hybridization in budding yeast. Nature Protocols. 7: 408-19. PMID 22301778 DOI: 10.1038/Nprot.2011.451  0.821
2012 Stöhr N, Köhn M, Lederer M, Glass M, Reinke C, Singer RH, Hüttelmaier S. IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling. Genes & Development. 26: 176-89. PMID 22279049 DOI: 10.1101/gad.177642.111  0.478
2012 Gu W, Katz Z, Wu B, Park HY, Li D, Lin S, Wells AL, Singer RH. Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1. Journal of Cell Science. 125: 81-91. PMID 22266909 DOI: 10.1242/Jcs.086132  0.793
2012 Lapidus KA, Nwokafor C, Scott D, Baroni TE, Tenenbaum SA, Hiroi N, Singer RH, Czaplinski K. Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 35-42. PMID 22240322 DOI: 10.1101/Lm.024471.111  0.747
2012 Patel VL, Mitra S, Harris R, Buxbaum AR, Lionnet T, Brenowitz M, Girvin M, Levy M, Almo SC, Singer RH, Chao JA. Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes & Development. 26: 43-53. PMID 22215810 DOI: 10.1101/Gad.177428.111  0.804
2012 Grünwald D, Singer RH. Multiscale dynamics in nucleocytoplasmic transport. Current Opinion in Cell Biology. 24: 100-6. PMID 22196930 DOI: 10.1016/J.Ceb.2011.11.011  0.314
2012 Patel V, Chao J, Singer R, Guha C. IMP1 Consensus Recognition Elements Identify Transcripts Affecting Tumor Cell Survival After Ionizing Radiation International Journal of Radiation Oncology*Biology*Physics. 84: S672-S673. DOI: 10.1016/J.Ijrobp.2012.07.1797  0.365
2012 Wu B, Katz Z, Yoon Y, Singer RH. ZBP1 and Ribosome Association with β Actin mRNA Measured by Fluorescence Fluctuation Spectroscopy Biophysical Journal. 102: 74a. DOI: 10.1016/J.Bpj.2011.11.431  0.79
2012 Singer RH, Lionnet T, Yoon Park H, Wu B, Trcek T, Hocine S, Larson D. Following Single mRNAs from Birth to Death in Living Cells Biophysical Journal. 102: 609a-610a. DOI: 10.1016/J.Bpj.2011.11.3323  0.782
2012 Yoon Park H, Yoon Y, Nwokafor C, Lopez-Jones M, Meng X, Follenzi A, Lim H, Singer RH. A Transgenic Mouse Model for Imaging Single RNA Dynamics In Vivo Biophysical Journal. 102: 600a. DOI: 10.1016/J.Bpj.2011.11.3267  0.499
2011 Trcek T, Larson DR, Moldón A, Query CC, Singer RH. Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell. 147: 1484-97. PMID 22196726 DOI: 10.1016/J.Cell.2011.11.051  0.826
2011 Hocine S, Singer RH. A date with telomerase: pick you up at S phase. Molecular Cell. 44: 685-6. PMID 22152472 DOI: 10.1016/J.Molcel.2011.11.013  0.721
2011 de Turris V, Nicholson P, Orozco RZ, Singer RH, Mühlemann O. Cotranscriptional effect of a premature termination codon revealed by live-cell imaging. Rna (New York, N.Y.). 17: 2094-107. PMID 22028363 DOI: 10.1261/rna.02918111  0.491
2011 Grünwald D, Singer RH, Rout M. Nuclear export dynamics of RNA-protein complexes. Nature. 475: 333-41. PMID 21776079 DOI: 10.1038/Nature10318  0.403
2011 Noordermeer D, de Wit E, Klous P, van de Werken H, Simonis M, Lopez-Jones M, Eussen B, de Klein A, Singer RH, de Laat W. Variegated gene expression caused by cell-specific long-range DNA interactions. Nature Cell Biology. 13: 944-51. PMID 21706023 DOI: 10.1038/Ncb2278  0.318
2011 Larson DR, Zenklusen D, Wu B, Chao JA, Singer RH. Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (New York, N.Y.). 332: 475-8. PMID 21512033 DOI: 10.1126/Science.1202142  0.731
2011 Fallini C, Zhang H, Su Y, Silani V, Singer RH, Rossoll W, Bassell GJ. The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3914-25. PMID 21389246 DOI: 10.1523/Jneurosci.3631-10.2011  0.627
2011 Wu B, Piatkevich KD, Lionnet T, Singer RH, Verkhusha VV. Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics. Current Opinion in Cell Biology. 23: 310-7. PMID 21242078 DOI: 10.1016/j.ceb.2010.12.004  0.443
2011 Lionnet T, Czaplinski K, Darzacq X, Shav-Tal Y, Wells AL, Chao JA, Park HY, de Turris V, Lopez-Jones M, Singer RH. A transgenic mouse for in vivo detection of endogenous labeled mRNA. Nature Methods. 8: 165-70. PMID 21240280 DOI: 10.1038/Nmeth.1551  0.776
2011 Gandhi SJ, Zenklusen D, Lionnet T, Singer RH. Transcription of functionally related constitutive genes is not coordinated. Nature Structural & Molecular Biology. 18: 27-34. PMID 21131977 DOI: 10.1038/Nsmb.1934  0.808
2011 Powrie EA, Zenklusen D, Singer RH. A nucleoporin, Nup60p, affects the nuclear and cytoplasmic localization of ASH1 mRNA in S. cerevisiae. Rna (New York, N.Y.). 17: 134-44. PMID 21036941 DOI: 10.1261/Rna.1210411  0.835
2011 Silverman SJ, Petti AA, Slavov N, Parsons L, Briehof R, Thiberge SY, Zenklusen D, Gandhi SJ, Larson DR, Singer RH, Botstein D. Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, (6946-6951) 10.1073/pnas.1002422107) Proceedings of the National Academy of Sciences of the United States of America. 108: 12185. DOI: 10.1073/Pnas.1109536108  0.735
2011 Larson DR, Fritzsch C, Sun L, Meng X, Condeelis J, Lawrence D, Singer R. Measurement and Modulation of Nuclear Receptor-Mediated Transcription in Single Cells Using Light Biophysical Journal. 100: 64a. DOI: 10.1016/J.Bpj.2010.12.548  0.407
2010 Lionnet T, Wu B, Grünwald D, Singer RH, Larson DR. Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 75: 113-26. PMID 21502409 DOI: 10.1101/Sqb.2010.75.057  0.378
2010 Hocine S, Singer RH, Grünwald D. RNA processing and export. Cold Spring Harbor Perspectives in Biology. 2: a000752. PMID 20961978 DOI: 10.1101/Cshperspect.A000752  0.783
2010 Zenklusen D, Singer RH. Analyzing mRNA expression using single mRNA resolution fluorescent in situ hybridization. Methods in Enzymology. 470: 641-59. PMID 20946829 DOI: 10.1016/S0076-6879(10)70026-4  0.778
2010 Grünwald D, Singer RH. In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport. Nature. 467: 604-7. PMID 20844488 DOI: 10.1038/Nature09438  0.455
2010 Trcek T, Singer RH. The cytoplasmic fate of an mRNP is determined cotranscriptionally: exception or rule? Genes & Development. 24: 1827-31. PMID 20810644 DOI: 10.1101/gad.1972810  0.814
2010 Lionnet T, Singer RH. Transcription, one allele at a time. Genome Biology. 11: 129. PMID 20796323 DOI: 10.1186/gb-2010-11-8-129  0.404
2010 Park HY, Buxbaum AR, Singer RH. Single mRNA tracking in live cells. Methods in Enzymology. 472: 387-406. PMID 20580973 DOI: 10.1016/S0076-6879(10)72003-6  0.851
2010 Wang D, Pezo RC, Corner G, Sison C, Lesser ML, Shenoy SM, Mariadason JM, Singer RH, Augenlicht LH. Altered dynamics of intestinal cell maturation in Apc1638N/+ mice. Cancer Research. 70: 5348-57. PMID 20570902 DOI: 10.1158/0008-5472.Can-09-4593  0.733
2010 Ben-Ari Y, Brody Y, Kinor N, Mor A, Tsukamoto T, Spector DL, Singer RH, Shav-Tal Y. The life of an mRNA in space and time. Journal of Cell Science. 123: 1761-74. PMID 20427315 DOI: 10.1242/Jcs.062638  0.537
2010 Silverman SJ, Petti AA, Slavov N, Parsons L, Briehof R, Thiberge SY, Zenklusen D, Gandhi SJ, Larson DR, Singer RH, Botstein D. Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate. Proceedings of the National Academy of Sciences of the United States of America. 107: 6946-51. PMID 20335538 DOI: 10.1073/Pnas.1002422107  0.778
2010 Chao JA, Patskovsky Y, Patel V, Levy M, Almo SC, Singer RH. ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes & Development. 24: 148-58. PMID 20080952 DOI: 10.1101/Gad.1862910  0.444
2010 Wu B, Singer RH. Protein-mRNA Interactions Observed in Living Cells By Dual-Color Fluorescence Fluctuation Spectroscopy Biophysical Journal. 98: 12a. DOI: 10.1016/J.BPJ.2009.12.071  0.502
2009 Oeffinger M, Zenklusen D, Ferguson A, Wei KE, El Hage A, Tollervey D, Chait BT, Singer RH, Rout MP. Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA. Molecular Cell. 36: 768-81. PMID 20005841 DOI: 10.1016/J.Molcel.2009.11.011  0.697
2009 Larson DR, Singer RH, Zenklusen D. A single molecule view of gene expression. Trends in Cell Biology. 19: 630-7. PMID 19819144 DOI: 10.1016/J.Tcb.2009.08.008  0.724
2009 Gu W, Pan F, Singer RH. Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells. Journal of Cell Science. 122: 1895-905. PMID 19461076 DOI: 10.1242/jcs.045278  0.54
2009 Darzacq X, Yao J, Larson DR, Causse SZ, Bosanac L, de Turris V, Ruda VM, Lionnet T, Zenklusen D, Guglielmi B, Tjian R, Singer RH. Imaging transcription in living cells. Annual Review of Biophysics. 38: 173-96. PMID 19416065 DOI: 10.1146/Annurev.Biophys.050708.133728  0.78
2009 Maier S, Daroqui MC, Scherer S, Roepcke S, Velcich A, Shenoy SM, Singer RH, Augenlicht LH. Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locus in colonic carcinoma cells. Journal of Cellular Physiology. 218: 638-42. PMID 19034928 DOI: 10.1002/jcp.21642  0.318
2009 Singer RH, Shav-Tal Y, Darzacq X, de Turris V, Chao J, Gruenwald D, Lionnet T, Shenoy S. Using fluorescent proteins to analyze gene expression in real-time Biophysical Journal. 96: 205a. DOI: 10.1016/J.Bpj.2008.12.1832  0.744
2008 Grünwald D, Singer RH, Czaplinski K. Cell biology of mRNA decay. Methods in Enzymology. 448: 553-77. PMID 19111194 DOI: 10.1016/S0076-6879(08)02627-X  0.514
2008 Zenklusen D, Larson DR, Singer RH. Single-RNA counting reveals alternative modes of gene expression in yeast. Nature Structural & Molecular Biology. 15: 1263-71. PMID 19011635 DOI: 10.1038/Nsmb.1514  0.741
2008 Singer RH. Highways for mRNA transport. Cell. 134: 722-3. PMID 18775304 DOI: 10.1016/j.cell.2008.08.020  0.434
2008 Aizer A, Brody Y, Ler LW, Sonenberg N, Singer RH, Shav-Tal Y. The dynamics of mammalian P body transport, assembly, and disassembly in vivo. Molecular Biology of the Cell. 19: 4154-66. PMID 18653466 DOI: 10.1091/Mbc.E08-05-0513  0.373
2008 Pezo RC, Gandhi SJ, Shirley LA, Pestell RG, Augenlicht LH, Singer RH. Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors. Cancer Research. 68: 4977-82. PMID 18593893 DOI: 10.1158/0008-5472.Can-07-6770  0.803
2008 Dictenberg JB, Swanger SA, Antar LN, Singer RH, Bassell GJ. A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Developmental Cell. 14: 926-39. PMID 18539120 DOI: 10.1016/j.devcel.2008.04.003  0.81
2008 Darzacq X, Singer RH. The dynamic range of transcription. Molecular Cell. 30: 545-6. PMID 18538652 DOI: 10.1016/j.molcel.2008.05.009  0.626
2008 Vainer G, Vainer-Mosse E, Pikarsky A, Shenoy SM, Oberman F, Yeffet A, Singer RH, Pikarsky E, Yisraeli JK. A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation. The Journal of Pathology. 215: 445-56. PMID 18535985 DOI: 10.1002/path.2376  0.431
2008 Gu W, Wells AL, Pan F, Singer RH. Feedback regulation between zipcode binding protein 1 and beta-catenin mRNAs in breast cancer cells. Molecular and Cellular Biology. 28: 4963-74. PMID 18490442 DOI: 10.1128/MCB.00266-08  0.536
2008 Deng Y, Singer RH, Gu W. Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes & Development. 22: 1037-50. PMID 18413716 DOI: 10.1101/Gad.1611308  0.658
2008 Rodriguez AJ, Czaplinski K, Condeelis JS, Singer RH. Mechanisms and cellular roles of local protein synthesis in mammalian cells. Current Opinion in Cell Biology. 20: 144-9. PMID 18378131 DOI: 10.1016/J.Ceb.2008.02.004  0.502
2008 Chang W, Zaarour RF, Reck-Peterson S, Rinn J, Singer RH, Snyder M, Novick P, Mooseker MS. Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body. Rna (New York, N.Y.). 14: 491-502. PMID 18218704 DOI: 10.1261/Rna.665008  0.408
2008 Chao JA, Patskovsky Y, Almo SC, Singer RH. Structural basis for the coevolution of a viral RNA-protein complex. Nature Structural & Molecular Biology. 15: 103-5. PMID 18066080 DOI: 10.1038/Nsmb1327  0.38
2008 Pezo RC, Singer RH. Nuclear microenvironment in cancer diagnosis and treatment. Journal of Cellular Biochemistry. 104: 1953-63. PMID 17477352 DOI: 10.1002/Jcb.21353  0.725
2007 Wells AL, Condeelis JS, Singer RH, Zenklusen D. Imaging real-time gene expression in living systems with single-transcript resolution: construct design and imaging system setup. Csh Protocols. 2007: pdb.top28. PMID 21356986 DOI: 10.1101/Pdb.Top28  0.725
2007 Wells AL, Condeelis JS, Singer RH, Zenklusen D. Imaging Real-Time Gene Expression in Living Systems with Single-Transcript Resolution: Single mRNA Particle Tracking with ImageJ-Based Analysis. Csh Protocols. 2007: pdb.prot4872. PMID 21356980 DOI: 10.1101/Pdb.Prot4872  0.714
2007 Wells AL, Condeelis JS, Singer RH, Zenklusen D. Imaging real-time gene expression in living systems with single-transcript resolution: image analysis of single mRNA transcripts. Csh Protocols. 2007: pdb.prot4871. PMID 21356979 DOI: 10.1101/Pdb.Prot4871  0.729
2007 Zenklusen D, Wells AL, Condeelis JS, Singer RH. Imaging real-time gene expression in living yeast. Csh Protocols. 2007: pdb.prot4870. PMID 21356978 DOI: 10.1101/Pdb.Prot4870  0.724
2007 Wells AL, Condeelis JS, Singer RH, Zenklusen D. Imaging real-time gene expression in Mammalian cells with single-transcript resolution. Csh Protocols. 2007: pdb.prot4869. PMID 21356977 DOI: 10.1101/Pdb.Prot4869  0.758
2007 Garcia M, Darzacq X, Devaux F, Singer RH, Jacq C. Yeast mitochondrial transcriptomics. Methods in Molecular Biology (Clifton, N.J.). 372: 505-28. PMID 18314748 DOI: 10.1007/978-1-59745-365-3_35  0.703
2007 Pan F, Hüttelmaier S, Singer RH, Gu W. ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Molecular and Cellular Biology. 27: 8340-51. PMID 17893325 DOI: 10.1128/MCB.00972-07  0.591
2007 Lapidus K, Wyckoff J, Mouneimne G, Lorenz M, Soon L, Condeelis JS, Singer RH. ZBP1 enhances cell polarity and reduces chemotaxis. Journal of Cell Science. 120: 3173-8. PMID 17878234 DOI: 10.1242/Jcs.000638  0.733
2007 Levsky JM, Shenoy SM, Chubb JR, Hall CB, Capodieci P, Singer RH. The spatial order of transcription in mammalian cells. Journal of Cellular Biochemistry. 102: 609-17. PMID 17849428 DOI: 10.1002/Jcb.21495  0.69
2007 Darzacq X, Shav-Tal Y, de Turris V, Brody Y, Shenoy SM, Phair RD, Singer RH. In vivo dynamics of RNA polymerase II transcription. Nature Structural & Molecular Biology. 14: 796-806. PMID 17676063 DOI: 10.1038/Nsmb1280  0.709
2007 Loudig O, Milova E, Brandwein-Gensler M, Massimi A, Belbin TJ, Childs G, Singer RH, Rohan T, Prystowsky MB. Molecular restoration of archived transcriptional profiles by complementary-template reverse-transcription (CT-RT). Nucleic Acids Research. 35: e94. PMID 17636051 DOI: 10.1093/Nar/Gkm510  0.394
2007 Zhang H, Xing L, Singer RH, Bassell GJ. QNQKE targeting motif for the SMN-Gemin multiprotein complexin neurons. Journal of Neuroscience Research. 85: 2657-67. PMID 17455327 DOI: 10.1002/Jnr.21308  0.641
2007 Rodriguez AJ, Condeelis J, Singer RH, Dictenberg JB. Imaging mRNA movement from transcription sites to translation sites. Seminars in Cell & Developmental Biology. 18: 202-8. PMID 17376719 DOI: 10.1016/J.Semcdb.2007.02.002  0.514
2007 Dong S, Li C, Zenklusen D, Singer RH, Jacobson A, He F. YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. Molecular Cell. 25: 559-73. PMID 17317628 DOI: 10.1016/J.Molcel.2007.01.012  0.771
2007 Garcia M, Darzacq X, Delaveau T, Jourdren L, Singer RH, Jacq C. Mitochondria-associated yeast mRNAs and the biogenesis of molecular complexes. Molecular Biology of the Cell. 18: 362-8. PMID 17108321 DOI: 10.1091/Mbc.E06-09-0827  0.645
2007 Gavis ER, Singer RH, Hüttelmaier S. 24 Localized Translation through Messenger RNA Localization Cold Spring Harbor Monograph Archive. 48: 689-717. DOI: 10.1101/087969767.48.689  0.532
2007 Darzacq X, Singer RH, Shav-Tal Y. Dissecting cellular activity from single genes to single mRNAs Chemical Analysis. 172: 29-39. DOI: 10.1002/9780470119501.ch2  0.676
2006 Pederson T, Singer RH. Nucleus and gene regulation. Current Opinion in Cell Biology. 18: 229-30. PMID 27486632 DOI: 10.1016/J.Ceb.2006.04.004  0.307
2006 Kittur N, Darzacq X, Roy S, Singer RH, Meier UT. Dynamic association and localization of human H/ACA RNP proteins. Rna (New York, N.Y.). 12: 2057-62. PMID 17135485 DOI: 10.1261/rna.249306  0.657
2006 Stöhr N, Lederer M, Reinke C, Meyer S, Hatzfeld M, Singer RH, Hüttelmaier S. ZBP1 regulates mRNA stability during cellular stress. The Journal of Cell Biology. 175: 527-34. PMID 17101699 DOI: 10.1083/jcb.200608071  0.496
2006 Czaplinski K, Singer RH. Pathways for mRNA localization in the cytoplasm. Trends in Biochemical Sciences. 31: 687-93. PMID 17084632 DOI: 10.1016/J.Tibs.2006.10.007  0.508
2006 Rodriguez AJ, Shenoy SM, Singer RH, Condeelis J. Visualization of mRNA translation in living cells. The Journal of Cell Biology. 175: 67-76. PMID 17030983 DOI: 10.1083/Jcb.200512137  0.503
2006 Rideau AP, Gooding C, Simpson PJ, Monie TP, Lorenz M, Hüttelmaier S, Singer RH, Matthews S, Curry S, Smith CW. A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain. Nature Structural & Molecular Biology. 13: 839-48. PMID 16936729 DOI: 10.1038/nsmb1137  0.312
2006 Zhang H, Xing L, Rossoll W, Wichterle H, Singer RH, Bassell GJ. Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8622-32. PMID 16914688 DOI: 10.1523/Jneurosci.3967-05.2006  0.633
2006 Shav-Tal Y, Darzacq X, Singer RH. Gene expression within a dynamic nuclear landscape. The Embo Journal. 25: 3469-79. PMID 16900099 DOI: 10.1038/sj.emboj.7601226  0.65
2006 Chubb JR, Trcek T, Shenoy SM, Singer RH. Transcriptional pulsing of a developmental gene. Current Biology : Cb. 16: 1018-25. PMID 16713960 DOI: 10.1016/j.cub.2006.03.092  0.779
2006 Darzacq X, Kittur N, Roy S, Shav-Tal Y, Singer RH, Meier UT. Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. The Journal of Cell Biology. 173: 207-18. PMID 16618814 DOI: 10.1083/jcb.200601105  0.659
2006 Chang L, Shav-Tal Y, Trcek T, Singer RH, Goldman RD. Assembling an intermediate filament network by dynamic cotranslation. The Journal of Cell Biology. 172: 747-58. PMID 16505169 DOI: 10.1083/Jcb.200511033  0.805
2006 Levsky JM, Braut SA, Singer RH. Single cell gene expression profiling: Multiplexed expression fluorescence in situ hybridization: Application to the analysis of cultured cells Cell Biology, Four-Volume Set. 4: 121-126. DOI: 10.1016/B978-012164730-8/50201-X  0.625
2005 Hüttelmaier S, Zenklusen D, Lederer M, Dictenberg J, Lorenz M, Meng X, Bassell GJ, Condeelis J, Singer RH. Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature. 438: 512-5. PMID 16306994 DOI: 10.1038/Nature04115  0.805
2005 Singer RH, Lawrence DS, Ovryn B, Condeelis J. Imaging of gene expression in living cells and tissues. Journal of Biomedical Optics. 10: 051406. PMID 16292943 DOI: 10.1117/1.2103032  0.416
2005 Capodieci P, Donovan M, Buchinsky H, Jeffers Y, Cordon-Cardo C, Gerald W, Edelson J, Shenoy SM, Singer RH. Gene expression profiling in single cells within tissue. Nature Methods. 2: 663-5. PMID 16118636 DOI: 10.1038/nmeth786  0.404
2005 Mingle LA, Okuhama NN, Shi J, Singer RH, Condeelis J, Liu G. Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. Journal of Cell Science. 118: 2425-33. PMID 15923655 DOI: 10.1242/Jcs.02371  0.47
2005 Darzacq X, Singer RH, Shav-Tal Y. Dynamics of transcription and mRNA export. Current Opinion in Cell Biology. 17: 332-9. PMID 15901505 DOI: 10.1016/j.ceb.2005.04.004  0.684
2005 Faul C, Hüttelmaier S, Oh J, Hachet V, Singer RH, Mundel P. Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. The Journal of Cell Biology. 169: 415-24. PMID 15883195 DOI: 10.1083/jcb.200411169  0.361
2005 Shav-Tal Y, Blechman J, Darzacq X, Montagna C, Dye BT, Patton JG, Singer RH, Zipori D. Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition. Molecular Biology of the Cell. 16: 2395-413. PMID 15758027 DOI: 10.1091/Mbc.E04-11-0992  0.673
2005 Condeelis J, Singer RH. How and why does beta-actin mRNA target? Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 97: 97-110. PMID 15601261 DOI: 10.1042/Bc20040063  0.446
2004 Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E, Singer RH, Segall JE, Condeelis JS. Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Research. 64: 8585-94. PMID 15574765 DOI: 10.1158/0008-5472.Can-04-1136  0.721
2004 Niessing D, Hüttelmaier S, Zenklusen D, Singer RH, Burley SK. She2p is a novel RNA binding protein with a basic helical hairpin motif. Cell. 119: 491-502. PMID 15537539 DOI: 10.1016/J.Cell.2004.10.018  0.744
2004 Shav-Tal Y, Singer RH, Darzacq X. Imaging gene expression in single living cells. Nature Reviews. Molecular Cell Biology. 5: 855-61. PMID 15459666 DOI: 10.1038/nrm1494  0.645
2004 Shav-Tal Y, Darzacq X, Shenoy SM, Fusco D, Janicki SM, Spector DL, Singer RH. Dynamics of single mRNPs in nuclei of living cells. Science (New York, N.Y.). 304: 1797-800. PMID 15205532 DOI: 10.1126/Science.1099754  0.81
2004 Gu W, Deng Y, Zenklusen D, Singer RH. A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes & Development. 18: 1452-65. PMID 15198983 DOI: 10.1101/Gad.1189004  0.815
2004 Fusco D, Bertrand E, Singer RH. Imaging of single mRNAs in the cytoplasm of living cells. Progress in Molecular and Subcellular Biology. 35: 135-50. PMID 15113083 DOI: 10.1007/978-3-540-74266-1_7  0.745
2004 Lorenz M, Yamaguchi H, Wang Y, Singer RH, Condeelis J. Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells. Current Biology : Cb. 14: 697-703. PMID 15084285 DOI: 10.1016/J.Cub.2004.04.008  0.3
2004 Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL. From silencing to gene expression: real-time analysis in single cells. Cell. 116: 683-98. PMID 15006351 DOI: 10.1016/S0092-8674(04)00171-0  0.388
2004 Lorenz M, DesMarais V, Macaluso F, Singer RH, Condeelis J. Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation. Cell Motility and the Cytoskeleton. 57: 207-17. PMID 14752805 DOI: 10.1002/Cm.10171  0.357
2003 Darzacq X, Powrie E, Gu W, Singer RH, Zenklusen D. RNA asymmetric distribution and daughter/mother differentiation in yeast. Current Opinion in Microbiology. 6: 614-20. PMID 14662358 DOI: 10.1016/J.Mib.2003.10.005  0.838
2003 Gromak N, Rideau A, Southby J, Scadden AD, Gooding C, Hüttelmaier S, Singer RH, Smith CW. The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. The Embo Journal. 22: 6356-64. PMID 14633994 DOI: 10.1093/emboj/cdg609  0.366
2003 Eom T, Antar LN, Singer RH, Bassell GJ. Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10433-44. PMID 14614102 DOI: 10.1523/Jneurosci.23-32-10433.2003  0.645
2003 Singer RH. RNA localization: visualization in real-time. Current Biology : Cb. 13: R673-5. PMID 12956970 DOI: 10.1016/S0960-9822(03)00605-5  0.363
2003 Matthiesen SH, Shenoy SM, Kim K, Singer RH, Satir BH. Role of the parafusin orthologue, PRP1, in microneme exocytosis and cell invasion in Toxoplasma gondii. Cellular Microbiology. 5: 613-24. PMID 12925131 DOI: 10.1046/j.1462-5822.2003.00305.x  0.314
2003 Zhang HL, Pan F, Hong D, Shenoy SM, Singer RH, Bassell GJ. Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6627-37. PMID 12878704 DOI: 10.1523/Jneurosci.23-16-06627.2003  0.67
2003 Levsky JM, Singer RH. Fluorescence in situ hybridization: past, present and future. Journal of Cell Science. 116: 2833-8. PMID 12808017 DOI: 10.1242/Jcs.00633  0.635
2003 Colón-Ramos DA, Salisbury JL, Sanders MA, Shenoy SM, Singer RH, García-Blanco MA. Asymmetric distribution of nuclear pore complexes and the cytoplasmic localization of beta2-tubulin mRNA in Chlamydomonas reinhardtii. Developmental Cell. 4: 941-52. PMID 12791277 DOI: 10.1016/S1534-5807(03)00163-1  0.402
2003 Tiruchinapalli DM, Oleynikov Y, Kelic S, Shenoy SM, Hartley A, Stanton PK, Singer RH, Bassell GJ. Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3251-61. PMID 12716932 DOI: 10.1523/Jneurosci.23-08-03251.2003  0.679
2003 Femino AM, Fogarty K, Lifshitz LM, Carrington W, Singer RH. Visualization of single molecules of mRNA in situ. Methods in Enzymology. 361: 245-304. PMID 12624916 DOI: 10.1016/S0076-6879(03)61015-3  0.383
2003 Oleynikov Y, Singer RH. Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization. Current Biology : Cb. 13: 199-207. PMID 12573215 DOI: 10.1016/S0960-9822(03)00044-7  0.525
2003 Fusco D, Accornero N, Lavoie B, Shenoy SM, Blanchard JM, Singer RH, Bertrand E. Single mRNA molecules demonstrate probabilistic movement in living mammalian cells. Current Biology : Cb. 13: 161-7. PMID 12546792 DOI: 10.1016/S0960-9822(02)01436-7  0.762
2003 Farina KL, Huttelmaier S, Musunuru K, Darnell R, Singer RH. Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. The Journal of Cell Biology. 160: 77-87. PMID 12507992 DOI: 10.1083/Jcb.200206003  0.8
2003 Levsky JM, Singer RH. Gene expression and the myth of the average cell. Trends in Cell Biology. 13: 4-6. PMID 12480334 DOI: 10.1016/S0962-8924(02)00002-8  0.653
2002 Chartrand P, Meng XH, Huttelmaier S, Donato D, Singer RH. Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA. Molecular Cell. 10: 1319-30. PMID 12504008 DOI: 10.1016/S1097-2765(02)00694-9  0.467
2002 Farina KL, Singer RH. The nuclear connection in RNA transport and localization. Trends in Cell Biology. 12: 466-72. PMID 12441250 DOI: 10.1016/S0962-8924(02)02357-7  0.798
2002 Wilson AJ, Velcich A, Arango D, Kurland AR, Shenoy SM, Pezo RC, Levsky JM, Singer RH, Augenlicht LH. Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. Cancer Research. 62: 6006-10. PMID 12414619  0.792
2002 Srisawat C, Houser-Scott F, Bertrand E, Xiao S, Singer RH, Engelke DR. An active precursor in assembly of yeast nuclear ribonuclease P. Rna (New York, N.Y.). 8: 1348-60. PMID 12403471 DOI: 10.1017/S1355838202027048  0.338
2002 Levsky JM, Shenoy SM, Pezo RC, Singer RH. Single-cell gene expression profiling. Science (New York, N.Y.). 297: 836-40. PMID 12161654 DOI: 10.1126/Science.1072241  0.797
2002 Liu G, Grant WM, Persky D, Latham VM, Singer RH, Condeelis J. Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions. Molecular Biology of the Cell. 13: 579-92. PMID 11854414 DOI: 10.1091/Mbc.01-03-0140  0.431
2002 Gu W, Pan F, Zhang H, Bassell GJ, Singer RH. A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. The Journal of Cell Biology. 156: 41-51. PMID 11781334 DOI: 10.1083/jcb.200105133  0.711
2001 Matthiesen SH, Shenoy SM, Kim K, Singer RH, Satir BH. A parafusin-related Toxoplasma protein in Ca2+-regulated secretory organelles. European Journal of Cell Biology. 80: 775-83. PMID 11831391 DOI: 10.1078/0171-9335-00214  0.327
2001 Hüttelmaier S, Illenberger S, Grosheva I, Rüdiger M, Singer RH, Jockusch BM. Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins. The Journal of Cell Biology. 155: 775-86. PMID 11724819 DOI: 10.1083/jcb.200105044  0.412
2001 Chartrand P, Singer RH, Long RM. RNP localization and transport in yeast. Annual Review of Cell and Developmental Biology. 17: 297-310. PMID 11687491 DOI: 10.1146/annurev.cellbio.17.1.297  0.494
2001 Zhang HL, Eom T, Oleynikov Y, Shenoy SM, Liebelt DA, Dictenberg JB, Singer RH, Bassell GJ. Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility. Neuron. 31: 261-75. PMID 11502257 DOI: 10.1016/S0896-6273(01)00357-9  0.637
2001 Latham VM, Yu EH, Tullio AN, Adelstein RS, Singer RH. A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts. Current Biology : Cb. 11: 1010-6. PMID 11470405 DOI: 10.1016/S0960-9822(01)00291-3  0.45
2001 Shestakova EA, Singer RH, Condeelis J. The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility. Proceedings of the National Academy of Sciences of the United States of America. 98: 7045-50. PMID 11416185 DOI: 10.1073/Pnas.121146098  0.436
2001 Gwizdek C, Bertrand E, Dargemont C, Lefebvre JC, Blanchard JM, Singer RH, Doglio A. Terminal minihelix, a novel RNA motif that directs polymerase III transcripts to the cell cytoplasm. Terminal minihelix and RNA export. The Journal of Biological Chemistry. 276: 25910-8. PMID 11342536 DOI: 10.1074/jbc.M100493200  0.4
2001 Long RM, Gu W, Meng X, Gonsalvez G, Singer RH, Chartrand P. An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast. The Journal of Cell Biology. 153: 307-18. PMID 11309412 DOI: 10.1083/jcb.153.2.307  0.527
2001 Bassell GJ, Singer RH. Neuronal RNA localization and the cytoskeleton. Results and Problems in Cell Differentiation. 34: 41-56. PMID 11288678 DOI: 10.1007/978-3-540-40025-7_3  0.636
2001 Fan Y, Braut SA, Lin Q, Singer RH, Skoultchi AI. Determination of transgenic loci by expression FISH. Genomics. 71: 66-9. PMID 11161798 DOI: 10.1006/Geno.2000.6403  0.355
2000 Vilardell J, Chartrand P, Singer RH, Warner JR. The odyssey of a regulated transcript. Rna (New York, N.Y.). 6: 1773-80. PMID 11142377 DOI: 10.1017/S135583820000145X  0.402
2000 Long RM, Gu W, Lorimer E, Singer RH, Chartrand P. She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA. The Embo Journal. 19: 6592-601. PMID 11101531 DOI: 10.1093/emboj/19.23.6592  0.461
2000 Kendall A, Hull MW, Bertrand E, Good PD, Singer RH, Engelke DR. A CBF5 mutation that disrupts nucleolar localization of early tRNA biosynthesis in yeast also suppresses tRNA gene-mediated transcriptional silencing. Proceedings of the National Academy of Sciences of the United States of America. 97: 13108-13. PMID 11069303 DOI: 10.1073/Pnas.240454997  0.37
2000 Chartrand P, Bertrand E, Singer RH, Long RM. Sensitive and high-resolution detection of RNA in situ. Methods in Enzymology. 318: 493-506. PMID 10890008 DOI: 10.1016/S0076-6879(00)18072-3  0.324
2000 Pereira MC, Singer RH, de Meirelles MN. Trypanosoma cruzi infection affects actin mRNA regulation in heart muscle cells. The Journal of Eukaryotic Microbiology. 47: 271-9. PMID 10847344 DOI: 10.1111/J.1550-7408.2000.Tb00047.X  0.435
2000 Pereira MC, Singer RH, de Meirelles MN. Ultrastructural distribution of poly (A)+ RNA during Trypanosoma cruzi-cardiomyocyte interaction in vitro: a quantitative analysis of the total mRNA content by in situ hybridization. The Journal of Eukaryotic Microbiology. 47: 264-70. PMID 10847343 DOI: 10.1111/J.1550-7408.2000.Tb00046.X  0.427
1999 Meirelles MN, Pereira MC, Singer RH, Soeiro MN, Garzoni LR, Silva DT, Barbosa HS, Araujo-Jorge TC, Masuda MO, Capella MA, Lopes AG, Vermelho AB. Trypanosoma cruzi-cardiomyocytes: new contributions regarding a better understanding of this interaction. Memã³Rias Do Instituto Oswaldo Cruz. 94: 149-52. PMID 10677703 DOI: 10.1590/S0074-02761999000700017  0.31
1999 Zhang HL, Singer RH, Bassell GJ. Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones. The Journal of Cell Biology. 147: 59-70. PMID 10508855 DOI: 10.1083/jcb.147.1.59  0.647
1999 Politz JC, Singer RH. In situ reverse transcription for detection of hybridization between oligonucleotides and their intracellular targets. Methods (San Diego, Calif.). 18: 281-5. PMID 10454986 DOI: 10.1006/meth.1999.0785  0.452
1999 Samarsky DA, Ferbeyre G, Bertrand E, Singer RH, Cedergren R, Fournier MJ. A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency. Proceedings of the National Academy of Sciences of the United States of America. 96: 6609-14. PMID 10359759 DOI: 10.1073/Pnas.96.12.6609  0.373
1999 Greenberg RA, Chin L, Femino A, Lee KH, Gottlieb GJ, Singer RH, Greider CW, DePinho RA. Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell. 97: 515-25. PMID 10338215 DOI: 10.1016/S0092-8674(00)80761-8  0.302
1999 Chartrand P, Meng XH, Singer RH, Long RM. Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo. Current Biology : Cb. 9: 333-6. PMID 10209102 DOI: 10.1016/S0960-9822(99)80144-4  0.357
1999 Politz JC, Tuft RA, Pederson T, Singer RH. Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells. Current Biology : Cb. 9: 285-91. PMID 10209094 DOI: 10.1016/S0960-9822(99)80136-5  0.451
1999 Shestakova EA, Wyckoff J, Jones J, Singer RH, Condeelis J. Correlation of beta-actin messenger RNA localization with metastatic potential in rat adenocarcinoma cell lines. Cancer Research. 59: 1202-5. PMID 10096548  0.307
1999 Bassell GJ, Oleynikov Y, Singer RH. The travels of mRNAs through all cells large and small. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 447-54. PMID 10064611 DOI: 10.1096/Fasebj.13.3.447  0.719
1998 Barcellini-Couget S, Fenard D, Bertrand E, Singer RH, Lefebvre JC, Doglio A. 3'-End modification of the adenoviral VA1 gene affects its expression in human cells: consequences for the design of chimeric VA1 RNA ribozymes. Antisense & Nucleic Acid Drug Development. 8: 379-90. PMID 9826265 DOI: 10.1089/Oli.1.1998.8.379  0.423
1998 Bertrand E, Chartrand P, Schaefer M, Shenoy SM, Singer RH, Long RM. Localization of ASH1 mRNA particles in living yeast. Molecular Cell. 2: 437-45. PMID 9809065 DOI: 10.1016/S1097-2765(00)80143-4  0.445
1998 Oleynikov Y, Singer RH. RNA localization: different zipcodes, same postman? Trends in Cell Biology. 8: 381-3. PMID 9789325 DOI: 10.1016/S0962-8924(98)01348-8  0.485
1998 Bertrand E, Houser-Scott F, Kendall A, Singer RH, Engelke DR. Nucleolar localization of early tRNA processing. Genes & Development. 12: 2463-8. PMID 9716399 DOI: 10.1101/Gad.12.16.2463  0.377
1998 Samarsky DA, Fournier MJ, Singer RH, Bertrand E. The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization. The Embo Journal. 17: 3747-57. PMID 9649444 DOI: 10.1093/Emboj/17.13.3747  0.332
1998 Chicurel ME, Singer RH, Meyer CJ, Ingber DE. Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions. Nature. 392: 730-3. PMID 9565036 DOI: 10.1038/33719  0.488
1998 Femino AM, Fay FS, Fogarty K, Singer RH. Visualization of single RNA transcripts in situ. Science (New York, N.Y.). 280: 585-90. PMID 9554849 DOI: 10.1126/science.280.5363.585  0.457
1998 Bassell GJ, Zhang H, Byrd AL, Femino AM, Singer RH, Taneja KL, Lifshitz LM, Herman IM, Kosik KS. Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 251-65. PMID 9412505  0.692
1998 Bassell GJ, Zhang H, Byrd AL, Femino AM, Singer RH, Taneja KL, Lifshitz LM, Herman IM, Kosik KS. Sorting of β-Actin mRNA and Protein to Neurites and Growth Cones in Culture The Journal of Neuroscience. 18: 251-265. DOI: 10.1523/JNEUROSCI.18-01-00251.1998  0.643
1997 Singer RH, Green MR. Compartmentalization of eukaryotic gene expression: causes and effects. Cell. 91: 291-4. PMID 9363936 DOI: 10.1016/S0092-8674(00)80411-0  0.315
1997 Long RM, Singer RH, Meng X, Gonzalez I, Nasmyth K, Jansen RP. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science (New York, N.Y.). 277: 383-7. PMID 9219698 DOI: 10.1126/Science.277.5324.383  0.541
1997 Davis BM, McCurrach ME, Taneja KL, Singer RH, Housman DE. Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts. Proceedings of the National Academy of Sciences of the United States of America. 94: 7388-93. PMID 9207101 DOI: 10.1073/pnas.94.14.7388  0.399
1997 Ross AF, Oleynikov Y, Kislauskis EH, Taneja KL, Singer RH. Characterization of a beta-actin mRNA zipcode-binding protein. Molecular and Cellular Biology. 17: 2158-65. PMID 9121465 DOI: 10.1128/Mcb.17.4.2158  0.441
1997 Kislauskis EH, Zhu X, Singer RH. beta-Actin messenger RNA localization and protein synthesis augment cell motility. The Journal of Cell Biology. 136: 1263-70. PMID 9087442 DOI: 10.1083/Jcb.136.6.1263  0.445
1997 Fay FS, Taneja KL, Shenoy S, Lifshitz L, Singer RH. Quantitative digital analysis of diffuse and concentrated nuclear distributions of nascent transcripts, SC35 and poly(A). Experimental Cell Research. 231: 27-37. PMID 9056409 DOI: 10.1006/excr.1996.3460  0.374
1997 Bassell G, Singer RH. mRNA and cytoskeletal filaments. Current Opinion in Cell Biology. 9: 109-15. PMID 9013679 DOI: 10.1016/S0955-0674(97)80159-7  0.699
1995 Long RM, Elliott DJ, Stutz F, Rosbash M, Singer RH. Spatial consequences of defective processing of specific yeast mRNAs revealed by fluorescent in situ hybridization. Rna (New York, N.Y.). 1: 1071-8. PMID 8595562  0.591
1995 Politz JC, Taneja KL, Singer RH. Characterization of hybridization between synthetic oligodeoxynucleotides and RNA in living cells. Nucleic Acids Research. 23: 4946-53. PMID 8559650 DOI: 10.1093/Nar/23.24.4946  0.477
1995 Taneja KL, McCurrach M, Schalling M, Housman D, Singer RH. Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues. The Journal of Cell Biology. 128: 995-1002. PMID 7896884 DOI: 10.1083/jcb.128.6.995  0.46
1994 Bassell GJ, Singer RH, Kosik KS. Association of poly(A) mRNA with microtubules in cultured neurons. Neuron. 12: 571-82. PMID 8155320 DOI: 10.1016/0896-6273(94)90213-5  0.733
1994 Somasundaran M, Zapp ML, Beattie LK, Pang L, Byron KS, Bassell GJ, Sullivan JL, Singer RH. Localization of HIV RNA in mitochondria of infected cells: potential role in cytopathogenicity. The Journal of Cell Biology. 126: 1353-60. PMID 8089170 DOI: 10.1083/Jcb.126.6.1353  0.621
1994 Latham VM, Kislauskis EH, Singer RH, Ross AF. Beta-actin mRNA localization is regulated by signal transduction mechanisms. The Journal of Cell Biology. 126: 1211-9. PMID 8063858 DOI: 10.1083/Jcb.126.5.1211  0.419
1994 Zhang G, Taneja KL, Singer RH, Green MR. Localization of pre-mRNA splicing in mammalian nuclei. Nature. 372: 809-12. PMID 7997273 DOI: 10.1038/372809A0  0.492
1994 Kislauskis EH, Zhu X, Singer RH. Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype. The Journal of Cell Biology. 127: 441-51. PMID 7929587 DOI: 10.1083/Jcb.127.2.441  0.435
1994 Bassell GJ, Powers CM, Taneja KL, Singer RH. Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts. The Journal of Cell Biology. 126: 863-76. PMID 7914201 DOI: 10.1083/jcb.126.4.863  0.709
1994 Bassell GJ, Taneja KL, Kislauskis EH, Sundell CL, Powers CM, Ross A, Singer RH. Actin filaments and the spatial positioning of mRNAS. Advances in Experimental Medicine and Biology. 358: 183-9. PMID 7801804 DOI: 10.1007/978-1-4615-2578-3_17  0.68
1993 Singer RH. RNA zipcodes for cytoplasmic addresses. Current Biology : Cb. 3: 719-21. PMID 15335871 DOI: 10.1016/0960-9822(93)90079-4  0.356
1993 Kislauskis EH, Li Z, Singer RH, Taneja KL. Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments. The Journal of Cell Biology. 123: 165-72. PMID 8408195 DOI: 10.1083/jcb.123.1.165  0.47
1993 Pockwinse SM, Lawrence JB, Singer RH, Stein JL, Lian JB, Stein GS. Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis. Bone. 14: 347-52. PMID 8363877 DOI: 10.1016/8756-3282(93)90163-5  0.342
1993 Rosbash M, Singer RH. RNA travel: tracks from DNA to cytoplasm. Cell. 75: 399-401. PMID 7693353 DOI: 10.1016/0092-8674(93)90373-X  0.522
1993 Singer RH. Spatial organization of mRNA within cells Journal of Cellular Biochemistry. 52: 125-126. DOI: 10.1002/JCB.240520202  0.408
1992 Singer RH. The cytoskeleton and mRNA localization. Current Opinion in Cell Biology. 4: 15-9. PMID 1558749 DOI: 10.1016/0955-0674(92)90053-F  0.494
1992 Kislauskis EH, Singer RH. Determinants of mRNA localization. Current Opinion in Cell Biology. 4: 975-8. PMID 1485968 DOI: 10.1016/0955-0674(92)90128-Y  0.512
1992 Taneja KL, Lifshitz LM, Fay FS, Singer RH. Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy. The Journal of Cell Biology. 119: 1245-60. PMID 1360014 DOI: 10.1083/Jcb.119.5.1245  0.411
1991 Pomeroy ME, Lawrence JB, Singer RH, Billings-Gagliardi S. Distribution of myosin heavy chain mRNA in embryonic muscle tissue visualized by ultrastructural in situ hybridization. Developmental Biology. 143: 58-67. PMID 1985024 DOI: 10.1016/0012-1606(91)90054-7  0.438
1991 Sundell CL, Singer RH. Requirement of microfilaments in sorting of actin messenger RNA. Science (New York, N.Y.). 253: 1275-7. PMID 1891715 DOI: 10.1126/Science.1891715  0.51
1991 Lawrence JB, Singer RH. Spatial organization of nucleic acid sequences within cells. Seminars in Cell Biology. 2: 83-101. PMID 1720683  0.331
1991 McNeil JA, Johnson CV, Carter KC, Singer RH, Lawrence JB. Localizing DNA and RNA within nuclei and chromosomes by fluorescence in situ hybridization. Genetic Analysis, Techniques and Applications. 8: 41-58. PMID 1712212 DOI: 10.1016/1050-3862(91)90049-W  0.363
1991 Johnson CV, Singer RH, Lawrence JB. Chapter 3 Fluorescent Detection of Nuclear RNA and DNA: Implications for Genome Organization Methods in Cell Biology. 35: 73-99. DOI: 10.1016/S0091-679X(08)60569-5  0.365
1990 Lawrence JB, Marselle LM, Byron KS, Johnson CV, Sullivan JL, Singer RH. Subcellular localization of low-abundance human immunodeficiency virus nucleic acid sequences visualized by fluorescence in situ hybridization. Proceedings of the National Academy of Sciences of the United States of America. 87: 5420-4. PMID 2371279 DOI: 10.1073/Pnas.87.14.5420  0.342
1990 Sundell CL, Singer RH. Actin mRNA localizes in the absence of protein synthesis. The Journal of Cell Biology. 111: 2397-403. PMID 2277064 DOI: 10.1083/Jcb.111.6.2397  0.505
1990 Taneja KL, Singer RH. Detection and localization of actin mRNA isoforms in chicken muscle cells by in situ hybridization using biotinated oligonucleotide probes. Journal of Cellular Biochemistry. 44: 241-52. PMID 2095368 DOI: 10.1002/jcb.240440406  0.464
1989 Singer RH, Lawrence JB, Silva F, Langevin GL, Pomeroy M, Billings-Gagliardi S. Strategies for ultrastructural visualization of biotinated probes hybridized to messenger RNA in situ. Current Topics in Microbiology and Immunology. 143: 55-69. PMID 2766803 DOI: 10.1007/978-3-642-74425-9_5  0.501
1989 Singer RH, Langevin GL, Lawrence JB. Ultrastructural visualization of cytoskeletal mRNAs and their associated proteins using double-label in situ hybridization. The Journal of Cell Biology. 108: 2343-53. PMID 2738094 DOI: 10.1083/Jcb.108.6.2343  0.484
1989 Lawrence JB, Taneja K, Singer RH. Temporal resolution and sequential expression of muscle-specific genes revealed by in situ hybridization. Developmental Biology. 133: 235-46. PMID 2651181 DOI: 10.1016/0012-1606(89)90314-X  0.495
1989 Lawrence JB, Singer RH, Marselle LM. Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization. Cell. 57: 493-502. PMID 2541917 DOI: 10.1016/0092-8674(89)90924-0  0.442
1988 Lawrence JB, Singer RH, Villnave CA, Stein JL, Stein GS. Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization. Proceedings of the National Academy of Sciences of the United States of America. 85: 463-7. PMID 3422437 DOI: 10.1073/Pnas.85.2.463  0.461
1987 Taneja K, Singer RH. Use of oligodeoxynucleotide probes for quantitative in situ hybridization to actin mRNA. Analytical Biochemistry. 166: 389-98. PMID 3434780 DOI: 10.1016/0003-2697(87)90589-6  0.405
1986 Lawrence JB, Singer RH. Intracellular localization of messenger RNAs for cytoskeletal proteins. Cell. 45: 407-15. PMID 3698103 DOI: 10.1016/0092-8674(86)90326-0  0.518
1985 Lawrence JB, Singer RH. Quantitative analysis of in situ hybridization methods for the detection of actin gene expression. Nucleic Acids Research. 13: 1777-99. PMID 3889842 DOI: 10.1093/Nar/13.5.1777  0.455
1984 Singer RH, Pudney JA. Filament-directed intercellular contacts during differentiation of cultured chick myoblasts. Tissue & Cell. 16: 17-29. PMID 6538352 DOI: 10.1016/0040-8166(84)90015-6  0.32
1982 Singer RH, Ward DC. Actin gene expression visualized in chicken muscle tissue culture by using in situ hybridization with a biotinated nucleotide analog. Proceedings of the National Academy of Sciences of the United States of America. 79: 7331-5. PMID 6961411 DOI: 10.1073/PNAS.79.23.7331  0.421
1981 Kabat-Zinn J, Singer RH. Sea urchin tube feet: unique structures that allow a cytological and molecular approach to the study of actin and its gene expression. The Journal of Cell Biology. 89: 109-14. PMID 6894447 DOI: 10.1083/Jcb.89.1.109  0.411
1979 Pudney J, Singer RH. Electron microscopic visualization of the filamentous reticulum in whole cultured presumptive chick myoblasts. The American Journal of Anatomy. 156: 321-36. PMID 575268 DOI: 10.1002/aja.1001560304  0.31
1978 Kessler-Icekson G, Singer RH, Yaffe D. The capacity of polyadenylated RNA from myogenic cells treated with actinomycin D to direct protein synthesis in a cell-free system. European Journal of Biochemistry / Febs. 88: 403-10. PMID 689026 DOI: 10.1111/J.1432-1033.1978.Tb12462.X  0.443
1978 Singer RH, Kessler-Icekson G. Stability of polyadenylated RNA in differentiating myogenic cells. European Journal of Biochemistry / Febs. 88: 395-402. PMID 689025 DOI: 10.1111/J.1432-1033.1978.Tb12461.X  0.381
1975 Spradling A, Singer RH, Lengyel J, Penman S. Methods with insect cells in suspension culture. I. Aedes albopictus. Methods in Cell Biology. 10: 185-94. PMID 1191393 DOI: 10.1016/S0091-679X(08)60737-2  0.528
1973 Singer RH, Penman S. Messenger RNA in HeLa cells: kinetics of formation and decay. Journal of Molecular Biology. 78: 321-34. PMID 4747634 DOI: 10.1016/0022-2836(73)90119-8  0.66
1973 Penman S, Goldstein E, Reichman M, Singer R. The relation of protein synthesis regulation and RNA metabolism. Acta Endocrinologica. Supplementum. 180: 168-91. PMID 4130167 DOI: 10.1530/Acta.0.074S168  0.577
1972 Singer RH, Penman S. Stability of HeLa cell mRNA in actinomycin. Nature. 240: 100-2. PMID 4118029 DOI: 10.1038/240100A0  0.677
Show low-probability matches.