Tae-wan Kim, Phd - Publications

Columbia University, New York, NY 
Neurogenetics, Neural Degeneration and Repair, Disease

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kwon OH, Cho YY, Kim TW, Chung S. O-GlcNAcylation of Amyloid-β Protein Precursor by Insulin Signaling Reduces Amyloid-β Production. Journal of Alzheimer's Disease : Jad. PMID 31156159 DOI: 10.3233/Jad-190060  0.316
2019 Cho YY, Kwon OH, Park MK, Kim TW, Chung S. Elevated cellular cholesterol in Familial Alzheimer's presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein. Plos One. 14: e0210535. PMID 30682043 DOI: 10.1371/Journal.Pone.0210535  0.367
2016 Finan GM, Realubit R, Chung S, Lütjohann D, Wang N, Cirrito JR, Karan C, Kim TW. Bioactive Compound Screen for Pharmacological Enhancers of Apolipoprotein E in Primary Human Astrocytes. Cell Chemical Biology. PMID 27889409 DOI: 10.1016/J.Chembiol.2016.10.015  0.32
2016 Cho JH, Ryu JK, Song SY, Hwang JH, Lee DK, Woo SM, Joo YE, Jeong S, Lee SO, Park BK, Cheon YK, Han J, Kim TN, Lee JK, Moon SH, ... ... Kim TH, et al. Prognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors: A Retrospective Nationwide Multicenter Study in South Korea. Pancreas. PMID 26765964 DOI: 10.1097/MPA.0000000000000586  0.487
2016 McIntire L, Hwang J, Gong G, Rinderspacher A, Deng S, Landry D, Kim T. DT-01-01: Plasma Membrane Monoamine Transporter Modulates Bace1 Activity Alzheimer's & Dementia. 12: P1134-P1134. DOI: 10.1016/J.Jalz.2016.07.007  0.567
2015 Chun YS, Kwon OH, Oh HG, Kim TW, McIntire LB, Park MK, Chung S. Threonine 576 residue of amyloid-β precursor protein regulates its trafficking and processing. Biochemical and Biophysical Research Communications. PMID 26471307 DOI: 10.1016/J.Bbrc.2015.10.037  0.385
2015 Chun YS, Park Y, Oh HG, Kim TW, Yang HO, Park MK, Chung S. O-GlcNAcylation promotes non-amyloidogenic processing of amyloid-β protein precursor via inhibition of endocytosis from the plasma membrane. Journal of Alzheimer's Disease : Jad. 44: 261-75. PMID 25208619 DOI: 10.3233/Jad-140096  0.354
2014 McIntire LB, Lee KI, Chang-Ileto B, Di Paolo G, Kim TW. Screening assay for small-molecule inhibitors of synaptojanin 1, a synaptic phosphoinositide phosphatase. Journal of Biomolecular Screening. 19: 585-94. PMID 24186361 DOI: 10.1177/1087057113510177  0.358
2013 An K, Klyubin I, Kim Y, Jung JH, Mably AJ, O'Dowd ST, Lynch T, Kanmert D, Lemere CA, Finan GM, Park JW, Kim TW, Walsh DM, Rowan MJ, Kim JH. Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo. Molecular Brain. 6: 47. PMID 24284042 DOI: 10.1186/1756-6606-6-47  0.467
2013 McIntire LB, Landman N, Kang MS, Finan GM, Hwang JC, Moore AZ, Park LS, Lin CS, Kim TW. Phenotypic assays for β-amyloid in mouse embryonic stem cell-derived neurons. Chemistry & Biology. 20: 956-67. PMID 23890013 DOI: 10.1016/J.Chembiol.2013.06.005  0.725
2013 Kang MS, Baek SH, Chun YS, Moore AZ, Landman N, Berman D, Yang HO, Morishima-Kawashima M, Osawa S, Funamoto S, Ihara Y, Di Paolo G, Park JH, Chung S, Kim TW. Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3. The Journal of Biological Chemistry. 288: 20868-82. PMID 23723072 DOI: 10.1074/Jbc.M112.445734  0.754
2012 McIntire LB, Berman DE, Myaeng J, Staniszewski A, Arancio O, Di Paolo G, Kim TW. Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15271-6. PMID 23115165 DOI: 10.1523/Jneurosci.2034-12.2012  0.364
2011 Paolo GD, Kim T. Linking lipids to Alzheimer's disease: cholesterol and beyond Nature Reviews Neuroscience. 12: 284-296. PMID 21448224 DOI: 10.1038/Nrn3012  0.319
2011 Finan GM, Okada H, Kim TW. BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin. The Journal of Biological Chemistry. 286: 12602-16. PMID 21245145 DOI: 10.1074/Jbc.M110.170217  0.599
2010 Oliveira TG, Chan RB, Tian H, Laredo M, Shui G, Staniszewski A, Zhang H, Wang L, Kim TW, Duff KE, Wenk MR, Arancio O, Di Paolo G. Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16419-28. PMID 21147981 DOI: 10.1523/Jneurosci.3317-10.2010  0.374
2010 Okada H, Zhang W, Peterhoff C, Hwang JC, Nixon RA, Ryu SH, Kim TW. Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2783-94. PMID 20354142 DOI: 10.1096/Fj.09-146357  0.708
2008 Lee SS, Shin JH, Woo CW, Hwang JC, Park CS, Kim HJ, Kim EY, Kim TH, Song HY. A new model of tracheal stenosis in dogs using combined bronchoscopic electrocautery and ethanol injection. Journal of Vascular and Interventional Radiology : Jvir. 19: 764-9. PMID 18440467 DOI: 10.1016/j.jvir.2008.01.025  0.494
2008 Berman DE, Dall'Armi C, Voronov SV, McIntire LB, Zhang H, Moore AZ, Staniszewski A, Arancio O, Kim TW, Di Paolo G. Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism. Nature Neuroscience. 11: 547-54. PMID 18391946 DOI: 10.1038/Nn.2100  0.374
2006 Landman N, Jeong SY, Shin SY, Voronov SV, Serban G, Kang MS, Park MK, Di Paolo G, Chung S, Kim TW. Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism. Proceedings of the National Academy of Sciences of the United States of America. 103: 19524-9. PMID 17158800 DOI: 10.1073/Pnas.0604954103  0.749
2006 Hwang JC, Okada H, Pandya K, Wang J, Lichtenthaler S, Kim T. P2-043: Developing cell-based assays for detection and quantification of the β-site-cleaved secreted APP ectodomain (sAPPβ) Alzheimer's & Dementia. 2: S244-S245. DOI: 10.1016/J.Jalz.2006.05.880  0.661
2006 Kim T, Landman N. O3-03-04 Alzheimer's & Dementia. 2: S57. DOI: 10.1016/J.Jalz.2006.05.208  0.704
2006 Finan GM, Hwang JC, Okada H, Small SA, Kim T. P4-065: Sortilin modulates the trafficking and activity of BACE1 Alzheimer's & Dementia. 2: S532-S532. DOI: 10.1016/J.Jalz.2006.05.1803  0.666
2005 Small SA, Kent K, Pierce A, Leung C, Kang MS, Okada H, Honig L, Vonsattel JP, Kim TW. Model-guided microarray implicates the retromer complex in Alzheimer's disease. Annals of Neurology. 58: 909-19. PMID 16315276 DOI: 10.1002/Ana.20667  0.567
2004 Landman N, Kim TW. Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling. Cytokine & Growth Factor Reviews. 15: 337-51. PMID 15450250 DOI: 10.1016/J.Cytogfr.2004.04.001  0.751
2003 Jung KM, Tan S, Landman N, Petrova K, Murray S, Lewis R, Kim PK, Kim DS, Ryu SH, Chao MV, Kim TW. Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor. The Journal of Biological Chemistry. 278: 42161-9. PMID 12913006 DOI: 10.1074/Jbc.M306028200  0.757
2003 Sun Y, Yao J, Kim TW, Tall AR. Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion. The Journal of Biological Chemistry. 278: 27688-94. PMID 12754201 DOI: 10.1074/Jbc.M300760200  0.391
2001 Hwang JC, Song HY, Kang SG, Suh JH, Ko GY, Lee DH, Kim TH, Jeong YK, Lee JH. Covered retrievable tracheobronchial hinged stent: an experimental study in dogs. Journal of Vascular and Interventional Radiology : Jvir. 12: 1429-36. PMID 11742020  0.482
2000 Tesco G, Melikian A, Kim T, Kovacs DM, Tanzi RE. Effects of staurosporine-mediated cell death on aβproduction and caspase-mediated cleavage of amyloid precursor protein and presenilins Neurobiology of Aging. 21: 68. DOI: 10.1016/S0197-4580(00)82528-2  0.308
2000 Cheng I, Yoo AS, Pack-Chung E, Park S, Saunders AJ, Tanzi RE, Kim T. Inhibition of capacitative calcium entry pathway potentiates presenilin-associated ‘-secretase activities of the amyloid β-precursor protein and Notch Neurobiology of Aging. 21: 118. DOI: 10.1016/S0197-4580(00)82331-3  0.31
1999 Saunders AJ, Kim T, Tanzi RE. BACE Maps to Chromosome 11 and a BACE Homolog, BACE2, Reside in the Obligate Down Syndrome Region of Chromosome 21 Science. 286: 1255-1255. DOI: 10.1126/Science.286.5443.1255A  0.327
1997 Kim TW, Tanzi RE. Presenilins and Alzheimer's disease. Current Opinion in Neurobiology. 7: 683-8. PMID 9384549 DOI: 10.1016/S0959-4388(97)80089-X  0.345
1997 Kim TW, Pettingell WH, Jung YK, Kovacs DM, Tanzi RE. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science (New York, N.Y.). 277: 373-6. PMID 9219695 DOI: 10.1126/Science.277.5324.373  0.314
1997 Kim TW, Pettingell WH, Hallmark OG, Moir RD, Wasco W, Tanzi RE. Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells. The Journal of Biological Chemistry. 272: 11006-10. PMID 9110991 DOI: 10.1074/Jbc.272.17.11006  0.314
1996 Tanzi RE, Kovacs DM, Kim TW, Moir RD, Guenette SY, Wasco W. The gene defects responsible for familial Alzheimer's disease. Neurobiology of Disease. 3: 159-68. PMID 8980016 DOI: 10.1006/Nbdi.1996.0016  0.347
1996 Irizarry MC, Kim TW, McNamara M, Tanzi RE, George JM, Clayton DF, Hyman BT. Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system. Journal of Neuropathology and Experimental Neurology. 55: 889-95. PMID 8759778 DOI: 10.1097/00005072-199608000-00004  0.355
1994 Kanno H, Kitawaki J, Maeda K, Kim T, Noguchi T, Yamamoto T, Okada H. [Regulation of aromatase in human choriocarcinoma cells]. Nihon Sanka Fujinka Gakkai Zasshi. 46: 449-56. PMID 8182306  0.482
1993 Kitawaki J, Kim T, Kanno H, Noguchi T, Yamamoto T, Okada H. Growth suppression of MCF-7 human breast cancer cells by aromatase inhibitors: a new system for aromatase inhibitor screening. The Journal of Steroid Biochemistry and Molecular Biology. 44: 667-70. PMID 8476780  0.458
1993 Noguchi T, Kitawaki J, Tamura T, Kim T, Kanno H, Yamamoto T, Okada H. Relationship between aromatase activity and steroid receptor levels in ovarian tumors from postmenopausal women. The Journal of Steroid Biochemistry and Molecular Biology. 44: 657-60. PMID 8476778  0.465
1993 Noguchi T, Kitawaki J, Tamura T, Kanno H, Kim T, Maeda K, Yamamoto T, Okada H. [Relationship among aromatase activity, estrogen receptor and progesterone receptor in ovarian tumors from postmenopausal women]. Nihon Sanka Fujinka Gakkai Zasshi. 45: 1123-8. PMID 8245591  0.454
Show low-probability matches.