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David N. Louis, MD - Publications

Affiliations: 
Pathology Harvard Medical School and Masssachusetts General Hospital, Boston, MA, United States 
Area:
molecular genetic basis of human brain tumors
Website:
http://pathology.hms.harvard.edu/mgh.htm

332 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Louis DN, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/j.cell.2019.06.024  0.76
2019 Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, et al. Data Sets for the Reporting of Tumors of the Central Nervous System. Archives of Pathology & Laboratory Medicine. PMID 31219344 DOI: 10.5858/arpa.2018-0565-OA  0.32
2019 Louis DN, Ellison DW, Brat DJ, Aldape K, Capper D, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, von Deimling A, Wesseling P. cIMPACT-NOW: A practical summary of diagnostic points from Round 1 updates. Brain Pathology (Zurich, Switzerland). PMID 31038238 DOI: 10.1111/bpa.12732  0.52
2019 Tanaka S, Batchelor TT, Iafrate AJ, Dias-Santagata D, Borger DR, Ellisen LW, Yang D, Louis DN, Cahill DP, Chi AS. PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma. Acta Neuropathologica Communications. 7: 66. PMID 31036078 DOI: 10.1186/s40478-019-0720-8  0.76
2018 Herrmann MD, Clunie DA, Fedorov A, Doyle SW, Pieper S, Klepeis V, Le LP, Mutter GL, Milstone DS, Schultz TJ, Kikinis R, Kotecha GK, Hwang DH, Andriole KP, Iafrate AJ, ... ... Louis DN, et al. Implementing the DICOM Standard for Digital Pathology. Journal of Pathology Informatics. 9: 37. PMID 30533276 DOI: 10.4103/jpi.jpi_42_18  0.92
2018 Bale TA, Jordan JT, Rapalino O, Ramamurthy N, Jessop N, DeWitt JC, Nardi V, Martinez-Lage Alvarez M, Frosch M, Batchelor TT, Louis DN, Iafrate AJ, Cahill DP, Lennerz JK. Financially Effective Test-Algorithm to Identify an Aggressive, EGFR-amplified Variant of IDH-Wildtype, Lower-Grade Diffuse Glioma. Neuro-Oncology. PMID 30496526 DOI: 10.1093/neuonc/noy201  0.76
2018 Brat DJ, Aldape K, Colman H, Holland EC, Louis DN, Jenkins RB, Kleinschmidt-DeMasters BK, Perry A, Reifenberger G, Stupp R, von Deimling A, Weller M. cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV". Acta Neuropathologica. PMID 30259105 DOI: 10.1007/s00401-018-1913-0  0.8
2018 Shirahata M, Ono T, Stichel D, Schrimpf D, Reuss DE, Sahm F, Koelsche C, Wefers A, Reinhardt A, Huang K, Sievers P, Shimizu H, Nanjo H, Kobayashi Y, Miyake Y, ... ... Louis DN, et al. Novel, improved grading system(s) for IDH-mutant astrocytic gliomas. Acta Neuropathologica. PMID 29687258 DOI: 10.1007/s00401-018-1849-4  0.52
2018 Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, ... ... Louis DN, et al. Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.). 360: 331-335. PMID 29674595 DOI: 10.1126/science.aao4750  0.76
2018 von Deimling A, Ono T, Shirahata M, Louis DN. Grading of Diffuse Astrocytic Gliomas: A Review of Studies Before and After the Advent of IDH Testing. Seminars in Neurology. 38: 19-23. PMID 29548048 DOI: 10.1055/s-0038-1636430  0.52
2018 Louis DN, Giannini C, Capper D, Paulus W, Figarella-Branger D, Lopes MB, Batchelor TT, Cairncross JG, van den Bent M, Wick W, Wesseling P. cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant. Acta Neuropathologica. PMID 29497819 DOI: 10.1007/s00401-018-1826-y  0.76
2018 Louis DN, Wesseling P, Paulus W, Giannini C, Batchelor TT, Cairncross JG, Capper D, Figarella-Branger D, Lopes MB, Wick W, van den Bent M. cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC). Acta Neuropathologica. PMID 29372318 DOI: 10.1007/s00401-018-1808-0  0.76
2017 DeWitt JC, Jordan JT, Frosch MP, Samore WR, Iafrate AJ, Louis DN, Lennerz JK. Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations. Neuro-Oncology. PMID 29016871 DOI: 10.1093/neuonc/nox120  0.4
2017 DeWitt JC, Mock A, Louis DN. The 2016 WHO classification of central nervous system tumors: what neurologists need to know. Current Opinion in Neurology. PMID 28901970 DOI: 10.1097/WCO.0000000000000490  0.32
2017 Louis DN, von Deimling A. Grading of diffuse astrocytic gliomas: Broders, Kernohan, Zülch, the WHO… and Shakespeare. Acta Neuropathologica. PMID 28801693 DOI: 10.1007/s00401-017-1765-z  0.52
2017 Thomas AA, Abrey LE, Terziev R, Raizer J, Martinez NL, Forsyth P, Paleologos N, Matasar M, Sauter CS, Moskowitz C, Nimer SD, DeAngelis LM, Kaley T, Grimm S, Louis DN, et al. Multicenter Phase II Study of Temozolomide and Myeloablative Chemotherapy with Autologous Stem Cell Transplant for Newly Diagnosed Anaplastic Oligodendroglioma. Neuro-Oncology. PMID 28472509 DOI: 10.1093/neuonc/nox086  0.68
2017 Bruner JM, Louis DN, McLendon R, Rosenblum MK, Archambault WT, Most S, Tihan T. The Utility of Expert Diagnosis in Surgical Neuropathology: Analysis of Consultations Reviewed at 5 National Comprehensive Cancer Network Institutions. Journal of Neuropathology and Experimental Neurology. 76: 189-194. PMID 28395084 DOI: 10.1093/jnen/nlw122  0.32
2017 Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, ... ... Louis DN, et al. Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science (New York, N.Y.). 355. PMID 28360267 DOI: 10.1126/science.aai8478  0.4
2016 Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, ... ... Louis DN, et al. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro-Oncology. PMID 28170043 DOI: 10.1093/neuonc/now235  0.76
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Gregory Cairncross J, Pfister SM, Rutkowski S, et al. cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathology (Zurich, Switzerland). PMID 27997995 DOI: 10.1111/bpa.12457  0.76
2016 Chi AS, Cahill DP, Larvie M, Louis DN. Case 38-2016. The New England Journal of Medicine. 375: 2381-2389. PMID 27974037 DOI: 10.1056/NEJMcpc1610101  0.36
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Cairncross JG, Pfister SM, Rutkowski S, et al. Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. Acta Neuropathologica. PMID 27909809 DOI: 10.1007/s00401-016-1646-x  0.76
2016 Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, ... ... Louis DN, et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. PMID 27806376 DOI: 10.1038/nature20123  0.4
2016 Aldape K, Nejad R, Louis DN, Zadeh G. Integrating molecular markers into the World Health Organization classification of CNS tumors: a survey of the neuro-oncology community. Neuro-Oncology. PMID 27688263 DOI: 10.1093/neuonc/now181  0.36
2016 Lennerz JK, McLaughlin HM, Baron JM, Rasmussen D, Shin MS, Berners-Lee N, Batten JM, Swoboda KJ, Gala MK, Winter HS, Schmahmann JD, Sweetser DA, Boswell M, Pacula M, Stenzinger A, ... ... Louis DN, et al. Health Care Infrastructure for Financially Sustainable Clinical Genomics. The Journal of Molecular Diagnostics : Jmd. PMID 27471182 DOI: 10.1016/j.jmoldx.2016.04.003  0.92
2016 Ostrom QT, Gittleman H, Kruchko C, Louis DN, Brat DJ, Gilbert MR, Petkov VI, Barnholtz-Sloan JS. Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying). Journal of Neuro-Oncology. PMID 27418206 DOI: 10.1007/s11060-016-2217-7  1
2016 Venteicher AS, Tirosh I, Hebert C, Escalante L, Martuza RL, Nahed BV, Curry WT, Cahill DP, Bernstein B, Louis DN, Regev A, Suva M. 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. Neurosurgery. 63: 158. PMID 27399421 DOI: 10.1227/01.neu.0000489712.44702.0d  0.36
2016 Ho AL, Koch MJ, Tanaka S, Eichler AF, Batchelor TT, Tanboon J, Louis DN, Cahill DP, Chi AS, Curry WT. Impact of histopathological transformation and overall survival in patients with progressive anaplastic glioma. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 27279154 DOI: 10.1016/j.jocn.2016.02.019  1
2016 Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathologica. 131: 803-20. PMID 27157931 DOI: 10.1007/s00401-016-1545-1  0.52
2016 Brastianos PK, Shankar GM, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M, Jones PS, Dunn IF, Nahed BV, Romero JM, Louis DN, Getz G, et al. Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy. Journal of the National Cancer Institute. 108. PMID 26498373 DOI: 10.1093/jnci/djv310  1
2015 Cahill DP, Louis DN, Cairncross JG. Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1. Cns Oncology. PMID 26545048 DOI: 10.2217/cns.15.32  0.68
2015 Cahill DP, Sloan AE, Nahed BV, Aldape KD, Louis DN, Ryken TC, Kalkanis SN, Olson JJ. The role of neuropathology in the management of patients with diffuse low grade glioma : A systematic review and evidence-based clinical practice guideline. Journal of Neuro-Oncology. PMID 26530263 DOI: 10.1007/s11060-015-1909-8  1
2015 Shankar GM, Lelic N, Gill CM, Thorner AR, Van Hummelen P, Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D, Brody RI, Duhaime AC, Taylor MD, ... ... Louis DN, et al. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology. Acta Neuropathologica. PMID 26487540 DOI: 10.1007/s00401-015-1492-2  1
2015 Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, ... ... Louis DN, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.CD-15-0369  0.76
2015 Shankar GM, Francis JM, Rinne ML, Ramkissoon SH, Huang FW, Venteicher AS, Akama-Garren EH, Kang YJ, Lelic N, Kim JC, Brown LE, Charbonneau SK, Golby AJ, Sekhar Pedamallu C, Hoang MP, ... ... Louis DN, et al. Rapid Intraoperative Molecular Characterization of Glioma. Jama Oncology. PMID 26181761 DOI: 10.1001/jamaoncol.2015.0917  0.52
2015 Louis DN, Feldman M, Carter AB, Dighe AS, Pfeifer JD, Bry L, Almeida JS, Saltz J, Braun J, Tomaszewski JE, Gilbertson JR, Sinard JH, Gerber GK, Galli SJ, Golden JA, et al. Computational Pathology. Archives of Pathology & Laboratory Medicine. PMID 26098131 DOI: 10.5858/arpa.2015-0093-SA  1
2014 Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, ... ... Louis DN, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathologica Communications. 2: 167. PMID 25589003 DOI: 10.1186/s40478-014-0167-x  1
2014 Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA. Computational pathology: an emerging definition. Archives of Pathology & Laboratory Medicine. 138: 1133-8. PMID 25171694 DOI: 10.5858/arpa.2014-0034-ED  0.92
2014 Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV, Kapur R, Shah K, Iafrate AJ, Curry WT, Loeffler JS, ... ... Louis DN, et al. Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discovery. 4: 1299-309. PMID 25139148 DOI: 10.1158/2159-8290.CD-14-0471  0.76
2014 Panageas KS, Reiner AS, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Urgoiti GB, Wen PY, Ligon KL, et al. Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors. Neuro-Oncology. 16: 1541-6. PMID 24997140 DOI: 10.1093/neuonc/nou083  1
2014 Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, et al. International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathology (Zurich, Switzerland). 24: 429-35. PMID 24990071 DOI: 10.1111/bpa.12171  0.52
2014 Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (New York, N.Y.). 344: 1396-401. PMID 24925914 DOI: 10.1126/science.1254257  1
2014 Mordes DA, Lynch K, Campbell S, Dias-Santagata D, Nose V, Louis DN, Hoang MP. VE1 antibody immunoreactivity in normal anterior pituitary and adrenal cortex without detectable BRAF V600E mutations. American Journal of Clinical Pathology. 141: 811-5. PMID 24838325 DOI: 10.1309/AJCP37TLZLTUAOJL  1
2014 Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, ... ... Louis DN, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 157: 580-94. PMID 24726434 DOI: 10.1016/j.cell.2014.02.030  1
2014 Cho TA, Chi AS, Schaefer PW, Louis DN. Case records of the Massachusetts General Hospital. Case 8-2014. A 29-year-old man with headache, vomiting, and diplopia. The New England Journal of Medicine. 370: 1049-59. PMID 24620869 DOI: 10.1056/NEJMcpc1214216  1
2014 Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, ... ... Louis DN, et al. Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nature Genetics. 46: 161-5. PMID 24413733 DOI: 10.1038/ng.2868  1
2013 Suvà ML, Louis DN. Next-generation molecular genetics of brain tumours. Current Opinion in Neurology. 26: 681-7. PMID 24184972 DOI: 10.1097/WCO.0000000000000027  1
2013 Routhier CA, Mochel MC, Lynch K, Dias-Santagata D, Louis DN, Hoang MP. Comparison of 2 monoclonal antibodies for immunohistochemical detection of BRAF V600E mutation in malignant melanoma, pulmonary carcinoma, gastrointestinal carcinoma, thyroid carcinoma, and gliomas. Human Pathology. 44: 2563-70. PMID 24071017 DOI: 10.1016/j.humpath.2013.06.018  1
2013 Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE. An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma. Cell Reports. 3: 1567-79. PMID 23707066 DOI: 10.1016/j.celrep.2013.04.021  1
2013 Riemenschneider MJ, Louis DN, Weller M, Hau P. Refined brain tumor diagnostics and stratified therapies: the requirement for a multidisciplinary approach. Acta Neuropathologica. 126: 21-37. PMID 23689616 DOI: 10.1007/s00401-013-1127-4  1
2013 Ozkumur E, Shah AM, Ciciliano JC, Emmink BL, Miyamoto DT, Brachtel E, Yu M, Chen PI, Morgan B, Trautwein J, Kimura A, Sengupta S, Stott SL, Karabacak NM, Barber TA, ... ... Louis DN, et al. Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Science Translational Medicine. 5: 179ra47. PMID 23552373 DOI: 10.1126/scitranslmed.3005616  1
2013 Chi AS, Batchelor TT, Yang D, Dias-Santagata D, Borger DR, Ellisen LW, Iafrate AJ, Louis DN. BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: e233-6. PMID 23547069 DOI: 10.1200/JCO.2012.46.0220  1
2013 Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nature Genetics. 45: 285-9. PMID 23334667 DOI: 10.1038/ng.2526  1
2013 Tanaka S, Louis DN, Curry WT, Batchelor TT, Dietrich J. Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end? Nature Reviews. Clinical Oncology. 10: 14-26. PMID 23183634 DOI: 10.1038/nrclinonc.2012.204  1
2013 Tanaka S, Chi AS, Wen PY, Louis DN, Iafrate AJ, Batchelor TT. Update on glioma treatments in the United States Japanese Journal of Neurosurgery. 22: 590-596.  1
2012 Louis DN. The next step in brain tumor classification: "Let us now praise famous men"… or molecules? Acta Neuropathologica. 124: 761-2. PMID 23151844 DOI: 10.1007/s00401-012-1067-4  1
2012 Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed Whole Slide Image viewing system. Studies in Health Technology and Informatics. 179: 239-49. PMID 22925804 DOI: 10.3233/978-1-61499-086-4-239  1
2012 Chi AS, Batchelor TT, Dias-Santagata D, Borger D, Stiles CD, Wang DL, Curry WT, Wen PY, Ligon KL, Ellisen L, Louis DN, Iafrate AJ. Prospective, high-throughput molecular profiling of human gliomas. Journal of Neuro-Oncology. 110: 89-98. PMID 22821383 DOI: 10.1007/s11060-012-0938-9  1
2012 Panageas KS, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Roldán Urgoiti GB, Wen PY, Ligon KL, Schiff D, et al. Initial treatment patterns over time for anaplastic oligodendroglial tumors. Neuro-Oncology. 14: 761-7. PMID 22661585 DOI: 10.1093/neuonc/nos065  1
2012 Batchelor TT, Sorensen AG, Louis DN. Case records of the Massachusetts General Hospital. Case 17-2012. A 54-year-old man with visual-field loss and a mass in the brain. The New England Journal of Medicine. 366: 2112-20. PMID 22646634 DOI: 10.1056/NEJMcpc1111574  1
2012 Rheinbay E, Louis DN, Bernstein BE, Suvà ML. A tell-tail sign of chromatin: histone mutations drive pediatric glioblastoma. Cancer Cell. 21: 329-31. PMID 22439930 DOI: 10.1016/j.ccr.2012.03.001  1
2012 Kanai R, Rabkin SD, Yip S, Sgubin D, Zaupa CM, Hirose Y, Louis DN, Wakimoto H, Martuza RL. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. Journal of the National Cancer Institute. 104: 42-55. PMID 22173583 DOI: 10.1093/jnci/djr509  1
2012 Chi AS, Batchelor TT, Kwak EL, Clark JW, Wang DL, Wilner KD, Louis DN, Iafrate AJ. Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: e30-3. PMID 22162573 DOI: 10.1200/JCO.2011.38.4586  1
2012 Yip S, Butterfield YS, Morozova O, Chittaranjan S, Blough MD, An J, Birol I, Chesnelong C, Chiu R, Chuah E, Corbett R, Docking R, Firme M, Hirst M, Jackman S, ... ... Louis DN, et al. Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. The Journal of Pathology. 226: 7-16. PMID 22072542 DOI: 10.1002/path.2995  1
2012 Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-Oncology. 14: 132-44. PMID 22067563 DOI: 10.1093/neuonc/nor195  1
2012 Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed whole slide image viewing system. Analytical Cellular Pathology (Amsterdam). 35: 65-73. PMID 22063731 DOI: 10.3233/ACP-2011-0042  1
2012 Jansen M, Mohapatra G, Betensky RA, Keohane C, Louis DN. Gain of chromosome arm 1q in atypical meningioma correlates with shorter progression-free survival. Neuropathology and Applied Neurobiology. 38: 213-9. PMID 21988727 DOI: 10.1111/j.1365-2990.2011.01222.x  1
2012 Lassman AB, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Gregory Cairncross J, Urgoiti GBR, Wen PY, Ligon KL, Schiff D, et al. Response to Weltman and Fleury Malheiros, re Lassman et al. Neuro-Oncology. 14: 677-678. DOI: 10.1093/neuonc/nos136  1
2011 Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, Akhavanfard S, Cahill DP, Aldape KD, Betensky RA, Louis DN, Iafrate AJ. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell. 20: 810-7. PMID 22137795 DOI: 10.1016/j.ccr.2011.11.005  1
2011 Louis DN, Virgin HW, Asa SL. "Next-generation" pathology and laboratory medicine. Archives of Pathology & Laboratory Medicine. 135: 1531-2. PMID 22129178 DOI: 10.5858/arpa.2011-0414-ED  1
2011 Young RH, Louis DN. The Warrens and other pioneering clinician pathologists of the Massachusetts General Hospital during its early years: an appreciation on the 200th anniversary of the hospital founding. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 1285-94. PMID 21926958 DOI: 10.1038/modpathol.2011.132  1
2011 Lassman AB, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Roldán GB, Wen PY, Ligon KL, Schiff D, et al. International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors. Neuro-Oncology. 13: 649-59. PMID 21636710 DOI: 10.1093/neuonc/nor040  1
2011 Dias-Santagata D, Lam Q, Vernovsky K, Vena N, Lennerz JK, Borger DR, Batchelor TT, Ligon KL, Iafrate AJ, Ligon AH, Louis DN, Santagata S. BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. Plos One. 6: e17948. PMID 21479234 DOI: 10.1371/journal.pone.0017948  1
2011 Camelo-Piragua S, Jansen M, Ganguly A, Kim JC, Cosper AK, Dias-Santagata D, Nutt CL, Iafrate AJ, Louis DN. A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53. Journal of Neuropathology and Experimental Neurology. 70: 110-5. PMID 21343879 DOI: 10.1097/NEN.0b013e31820565f9  1
2011 Horbinski C, Kofler J, Yeaney G, Camelo-Piragua S, Venneti S, Louis DN, Perry A, Murdoch G, Nikiforova M. Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas. Brain Pathology (Zurich, Switzerland). 21: 564-74. PMID 21314850 DOI: 10.1111/j.1750-3639.2011.00480.x  1
2011 Schindler G, Capper D, Meyer J, Janzarik W, Omran H, Herold-Mende C, Schmieder K, Wesseling P, Mawrin C, Hasselblatt M, Louis DN, Korshunov A, Pfister S, Hartmann C, Paulus W, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathologica. 121: 397-405. PMID 21274720 DOI: 10.1007/s00401-011-0802-6  1
2011 Mohapatra G, Engler DA, Starbuck KD, Kim JC, Bernay DC, Scangas GA, Rousseau A, Batchelor TT, Betensky RA, Louis DN. Genome-wide comparison of paired fresh frozen and formalin-fixed paraffin-embedded gliomas by custom BAC and oligonucleotide array comparative genomic hybridization: facilitating analysis of archival gliomas. Acta Neuropathologica. 121: 529-43. PMID 21080181 DOI: 10.1007/s00401-010-0773-z  1
2010 McDaniel S, Minnier J, Betensky RA, Mohapatra G, Shen Y, Gusella JF, Louis DN, Cai T. Assessing Population Level Genetic Instability via Moving Average. Statistics in Biosciences. 2: 120-136. PMID 22866169 DOI: 10.1007/s12561-010-9028-8  1
2010 Jansen M, Yip S, Louis DN. Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers. The Lancet. Neurology. 9: 717-26. PMID 20610347 DOI: 10.1016/S1474-4422(10)70105-8  1
2010 Batchelor TT, Duda DG, di Tomaso E, Ancukiewicz M, Plotkin SR, Gerstner E, Eichler AF, Drappatz J, Hochberg FH, Benner T, Louis DN, Cohen KS, Chea H, Exarhopoulos A, Loeffler JS, et al. Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2817-23. PMID 20458050 DOI: 10.1200/JCO.2009.26.3988  1
2010 Dias-Santagata D, Akhavanfard S, David SS, Vernovsky K, Kuhlmann G, Boisvert SL, Stubbs H, McDermott U, Settleman J, Kwak EL, Clark JW, Isakoff SJ, Sequist LV, Engelman JA, Lynch TJ, ... ... Louis DN, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. Embo Molecular Medicine. 2: 146-58. PMID 20432502 DOI: 10.1002/emmm.201000070  1
2010 van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K. Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 29: 3185-95. PMID 20305695 DOI: 10.1038/onc.2010.75  1
2010 Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, ... ... Louis DN, et al. A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Research. 70: 2158-64. PMID 20215515 DOI: 10.1158/0008-5472.CAN-09-3458  1
2010 Zhang X, Gejman R, Mahta A, Zhong Y, Rice KA, Zhou Y, Cheunsuchon P, Louis DN, Klibanski A. Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. Cancer Research. 70: 2350-8. PMID 20179190 DOI: 10.1158/0008-5472.CAN-09-3885  1
2010 Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, Popoff S, Nutt CL, Louis DN, Cairncross JG, Gilbert MR, Phillips HS, Mehta MP, Chakravarti A, Pelloski CE, et al. A multigene predictor of outcome in glioblastoma. Neuro-Oncology. 12: 49-57. PMID 20150367 DOI: 10.1093/neuonc/nop007  1
2010 Camelo-Piragua S, Jansen M, Ganguly A, Kim JC, Louis DN, Nutt CL. Mutant IDH1-specific immunohistochemistry distinguishes diffuse astrocytoma from astrocytosis. Acta Neuropathologica. 119: 509-11. PMID 20044756 DOI: 10.1007/s00401-009-0632-y  1
2009 Stamoulis C, Betensky RA, Mohapatra G, Louis DN. Application of signal processing techniques for estimating regions of copy number variations in human meningioma DNA. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 6973-6. PMID 19964720 DOI: 10.1109/IEMBS.2009.5333851  1
2009 Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, et al. Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Archives of Pathology & Laboratory Medicine. 133: 1949-53. PMID 19961250 DOI: 10.1043/1543-2165-133.12.1949  1
2009 Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG, Loeffler JS, Louis DN, Mohapatra G. Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome. Journal of Neuropathology and Experimental Neurology. 68: 1155-65. PMID 19918127 DOI: 10.1097/NEN.0b013e3181ba3952  1
2009 Gerstner ER, Yip S, Wang DL, Louis DN, Iafrate AJ, Batchelor TT. Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma. Neurology. 73: 1509-10. PMID 19884580 DOI: 10.1212/WNL.0b013e3181bf9907  1
2009 Snuderl M, Eichler AF, Ligon KL, Vu QU, Silver M, Betensky RA, Ligon AH, Wen PY, Louis DN, Iafrate AJ. Polysomy for chromosomes 1 and 19 predicts earlier recurrence in anaplastic oligodendrogliomas with concurrent 1p/19q loss. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6430-7. PMID 19808867 DOI: 10.1158/1078-0432.CCR-09-0867  1
2009 Yip S, Miao J, Cahill DP, Iafrate AJ, Aldape K, Nutt CL, Louis DN. MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4622-9. PMID 19584161 DOI: 10.1158/1078-0432.CCR-08-3012  1
2009 Aghi MK, Batchelor TT, Louis DN, Barker FG, Curry WT. Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q. Journal of Neuro-Oncology. 93: 115-20. PMID 19430887 DOI: 10.1007/s11060-009-9826-3  1
2009 DeSantis SM, Houseman EA, Coull BA, Louis DN, Mohapatra G, Betensky RA. A latent class model with hidden Markov dependence for array CGH data. Biometrics. 65: 1296-305. PMID 19397578 DOI: 10.1111/j.1541-0420.2009.01226.x  1
2009 Gabeau-Lacet D, Aghi M, Betensky RA, Barker FG, Loeffler JS, Louis DN. Bone involvement predicts poor outcome in atypical meningioma. Journal of Neurosurgery. 111: 464-71. PMID 19267533 DOI: 10.3171/2009.2.JNS08877  1
2009 Koga T, Morita A, Maruyama K, Tanaka M, Ino Y, Shibahara J, Louis DN, Reifenberger G, Itami J, Hara R, Saito N, Todo T. Long-term control of disseminated pleomorphic xanthoastrocytoma with anaplastic features by means of stereotactic irradiation. Neuro-Oncology. 11: 446-51. PMID 19164434 DOI: 10.1215/15228517-2008-112  1
2009 Du J, Bernasconi P, Clauser KR, Mani DR, Finn SP, Beroukhim R, Burns M, Julian B, Peng XP, Hieronymus H, Maglathlin RL, Lewis TA, Liau LM, Nghiemphu P, Mellinghoff IK, ... Louis DN, et al. Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy. Nature Biotechnology. 27: 77-83. PMID 19098899 DOI: 10.1038/nbt.1513  1
2008 Cahill DP, Codd PJ, Batchelor TT, Curry WT, Louis DN. MSH6 inactivation and emergent temozolomide resistance in human glioblastomas. Clinical Neurosurgery. 55: 165-71. PMID 19248684  1
2008 Stegh AH, Chin L, Louis DN, DePinho RA. What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator. Cell Cycle (Georgetown, Tex.). 7: 2833-9. PMID 18769159  1
2008 Stegh AH, Kesari S, Mahoney JE, Jenq HT, Forloney KL, Protopopov A, Louis DN, Chin L, DePinho RA. Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 10703-8. PMID 18669646 DOI: 10.1073/pnas.0712034105  1
2008 Iafrate AJ, Louis DN. "MGMT for pt mgmt": is methylguanine-DNA methyltransferase testing ready for patient management? The Journal of Molecular Diagnostics : Jmd. 10: 308-10. PMID 18556768 DOI: 10.2353/jmoldx.2008.080043  1
2008 de la Iglesia N, Konopka G, Lim KL, Nutt CL, Bromberg JF, Frank DA, Mischel PS, Louis DN, Bonni A. Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5870-8. PMID 18524891 DOI: 10.1523/JNEUROSCI.5385-07.2008  1
2008 Mohile NA, Forsyth P, Stewart D, Raizer JJ, Paleologos N, Kewalramani T, Louis DN, Cairncross JG, Abrey LE. A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis. Journal of Neuro-Oncology. 89: 187-93. PMID 18458821 DOI: 10.1007/s11060-008-9603-8  1
2008 Lawlor MW, Nielsen GP, Louis DN. Malignant solitary fibrous tumour of the meninges with marked amianthoid fibre deposition. Neuropathology and Applied Neurobiology. 34: 569-72. PMID 18298634 DOI: 10.1111/j.1365-2990.2008.00943.x  1
2008 Yip S, Iafrate AJ, Louis DN. Molecular diagnostic testing in malignant gliomas: a practical update on predictive markers. Journal of Neuropathology and Experimental Neurology. 67: 1-15. PMID 18091559 DOI: 10.1097/nen.0b013e31815f65fb  1
2007 Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes & Development. 21: 2683-710. PMID 17974913 DOI: 10.1101/gad.1596707  1
2007 Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathologica. 114: 97-109. PMID 17618441 DOI: 10.1007/s00401-007-0243-4  1
2007 Betensky RA, Louis DN, Cairncross JG. Tests of association under misclassification: application to histological sampling in oncology. Statistics in Medicine. 26: 4808-16. PMID 17476651 DOI: 10.1002/sim.2895  1
2007 Abrey LE, Louis DN, Paleologos N, Lassman AB, Raizer JJ, Mason W, Finlay J, MacDonald DR, DeAngelis LM, Cairncross JG. Survey of treatment recommendations for anaplastic oligodendroglioma. Neuro-Oncology. 9: 314-8. PMID 17435180 DOI: 10.1215/15228517-2007-002  1
2007 Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, Reavie LB, Batchelor TT, Futreal PA, Stratton MR, Curry WT, Iafrate AJ, Louis DN. Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2038-45. PMID 17404084 DOI: 10.1158/1078-0432.CCR-06-2149  1
2007 Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, ... ... Louis DN, et al. Patterns of somatic mutation in human cancer genomes. Nature. 446: 153-8. PMID 17344846 DOI: 10.1038/nature05610  1
2007 Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron. 53: 503-17. PMID 17296553 DOI: 10.1016/j.neuron.2007.01.009  1
2007 Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell. 11: 83-95. PMID 17222792 DOI: 10.1016/j.ccr.2006.11.021  1
2007 Stegh AH, Kim H, Bachoo RM, Forloney KL, Zhang J, Schulze H, Park K, Hannon GJ, Yuan J, Louis DN, DePinho RA, Chin L. Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes & Development. 21: 98-111. PMID 17210792 DOI: 10.1101/gad.1480007  1
2007 Mueller W, Nutt CL, Ehrich M, Riemenschneider MJ, von Deimling A, van den Boom D, Louis DN. Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. Oncogene. 26: 583-93. PMID 16909125 DOI: 10.1038/sj.onc.1209805  1
2006 Louis DN. Molecular pathology of malignant gliomas. Annual Review of Pathology. 1: 97-117. PMID 18039109 DOI: 10.1146/annurev.pathol.1.110304.100043  1
2006 Mizoguchi M, Betensky RA, Batchelor TT, Bernay DC, Louis DN, Nutt CL. Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival. Journal of Neuropathology and Experimental Neurology. 65: 1181-8. PMID 17146292 DOI: 10.1097/01.jnen.0000248549.14962.b2  1
2006 Rousseau A, Nutt CL, Betensky RA, Iafrate AJ, Han M, Ligon KL, Rowitch DH, Louis DN. Expression of oligodendroglial and astrocytic lineage markers in diffuse gliomas: use of YKL-40, ApoE, ASCL1, and NKX2-2. Journal of Neuropathology and Experimental Neurology. 65: 1149-56. PMID 17146289 DOI: 10.1097/01.jnen.0000248543.90304.2b  1
2006 Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, Richardson A, Khatry D, Feng B, Sinha R, Louis DN, Quackenbush J, Black PM, Chin L, DePinho RA. Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Research. 66: 11502-13. PMID 17114236 DOI: 10.1158/0008-5472.CAN-06-2072  1
2006 Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 12873-8. PMID 16908838 DOI: 10.1073/pnas.0605496103  1
2006 Iliopoulos O, Chan-Smutko G, Gonzalez RG, Louis DN, Stone JR. Case records of the Massachusetts General Hospital. Case 23-2006. A 36-year-old man with numbness in the left [corrected] hand and hypertension. The New England Journal of Medicine. 355: 394-402. PMID 16870919 DOI: 10.1056/NEJMcpc069014  1
2006 Sequist LV, Joshi VA, Jänne PA, Bell DW, Fidias P, Lindeman NI, Louis DN, Lee JC, Mark EJ, Longtine J, Verlander P, Kucherlapati R, Meyerson M, Haber DA, Johnson BE, et al. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4403s-4408s. PMID 16857818 DOI: 10.1158/1078-0432.CCR-06-0099  1
2006 Riemenschneider MJ, Betensky RA, Pasedag SM, Louis DN. AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling. Cancer Research. 66: 5618-23. PMID 16740698 DOI: 10.1158/0008-5472.CAN-06-0364  1
2006 Mohapatra G, Betensky RA, Miller ER, Carey B, Gaumont LD, Engler DA, Louis DN. Glioma test array for use with formalin-fixed, paraffin-embedded tissue: array comparative genomic hybridization correlates with loss of heterozygosity and fluorescence in situ hybridization. The Journal of Molecular Diagnostics : Jmd. 8: 268-76. PMID 16645215 DOI: 10.2353/jmoldx.2006.050109  1
2006 Hunter C, Smith R, Cahill DP, Stephens P, Stevens C, Teague J, Greenman C, Edkins S, Bignell G, Davies H, O'Meara S, Parker A, Avis T, Barthorpe S, Brackenbury L, ... ... Louis DN, et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. Cancer Research. 66: 3987-91. PMID 16618716 DOI: 10.1158/0008-5472.CAN-06-0127  1
2006 Engler DA, Mohapatra G, Louis DN, Betensky RA. A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations. Biostatistics (Oxford, England). 7: 399-421. PMID 16401686 DOI: 10.1093/biostatistics/kxj015  1
2005 Aghi M, Gaviani P, Henson JW, Batchelor TT, Louis DN, Barker FG. Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8600-5. PMID 16361543 DOI: 10.1158/1078-0432.CCR-05-0713  1
2005 Barnet CS, Louis DN, Kohane DS. Tissue injury from tricyclic antidepressants used as local anesthetics. Anesthesia and Analgesia. 101: 1838-43. PMID 16301270 DOI: 10.1213/01.ANE.0000184129.50312.C1  1
2005 Dong S, Nutt CL, Betensky RA, Stemmer-Rachamimov AO, Denko NC, Ligon KL, Rowitch DH, Louis DN. Histology-based expression profiling yields novel prognostic markers in human glioblastoma. Journal of Neuropathology and Experimental Neurology. 64: 948-55. PMID 16254489  1
2005 Riemenschneider MJ, Mueller W, Betensky RA, Mohapatra G, Louis DN. In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation. The American Journal of Pathology. 167: 1379-87. PMID 16251422 DOI: 10.1016/S0002-9440(10)61225-4  1
2005 Henson JW, Hobbs W, Chakravarti A, Louis DN. Alterations in p53, p21, and MIB-1 labeling index in primary human astrocytomas following radiation therapy. Journal of Neuro-Oncology. 74: 151-4. PMID 16193385 DOI: 10.1007/s11060-004-6911-5  1
2005 McDonald JM, See SJ, Tremont IW, Colman H, Gilbert MR, Groves M, Burger PC, Louis DN, Giannini C, Fuller G, Passe S, Blair H, Jenkins RB, Yang H, Ledoux A, et al. The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors. Cancer. 104: 1468-77. PMID 16088966 DOI: 10.1002/cncr.21338  1
2005 Ma D, Nutt CL, Shanehsaz P, Peng X, Louis DN, Kaetzel DM. Autocrine platelet-derived growth factor-dependent gene expression in glioblastoma cells is mediated largely by activation of the transcription factor sterol regulatory element binding protein and is associated with altered genotype and patient survival in human brain tumors. Cancer Research. 65: 5523-34. PMID 15994924 DOI: 10.1158/0008-5472.CAN-04-2582  1
2005 Shih HA, Betensky RA, Dorfman MV, Louis DN, Loeffler JS, Batchelor TT. Genetic analyses for predictors of radiation response in glioblastoma. International Journal of Radiation Oncology, Biology, Physics. 63: 704-10. PMID 15978739 DOI: 10.1016/j.ijrobp.2005.03.059  1
2005 Dahiya S, Sarkar C, Hedley-Whyte ET, Sharma MC, Zervas NT, Sridhar E, Louis DN. Spindle cell oncocytoma of the adenohypophysis: report of two cases. Acta Neuropathologica. 110: 97-9. PMID 15973544 DOI: 10.1007/s00401-005-1009-5  0.8
2005 Mueller W, Mizoguchi M, Silen E, D'Amore K, Nutt CL, Louis DN. Mutations of the PIK3CA gene are rare in human glioblastoma. Acta Neuropathologica. 109: 654-5. PMID 15924252 DOI: 10.1007/s00401-005-1001-0  1
2005 Betensky RA, Nutt CL, Batchelor TT, Louis DN. Statistical considerations for immunohistochemistry panel development after gene expression profiling of human cancers. The Journal of Molecular Diagnostics : Jmd. 7: 276-82. PMID 15858152 DOI: 10.1016/S1525-1578(10)60555-7  1
2005 Riemenschneider MJ, Bell DW, Haber DA, Louis DN. Pulmonary adenocarcinomas with mutant epidermal growth factor receptors. The New England Journal of Medicine. 352: 1724-5. PMID 15843680 DOI: 10.1056/NEJM200504213521622  1
2005 Nutt CL, Betensky RA, Brower MA, Batchelor TT, Louis DN, Stemmer-Rachamimov AO. YKL-40 is a differential diagnostic marker for histologic subtypes of high-grade gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2258-64. PMID 15788675 DOI: 10.1158/1078-0432.CCR-04-1601  1
2005 Kreiger PA, Okada Y, Simon S, Rorke LB, Louis DN, Golden JA. Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas. Acta Neuropathologica. 109: 387-92. PMID 15739101 DOI: 10.1007/s00401-004-0976-2  1
2005 Voloschin AD, Louis DN, Cosgrove GR, Batchelor TT. Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study. Neuro-Oncology. 7: 97-100. PMID 15701287 DOI: 10.1215/S1152851704000560  1
2004 Mizoguchi M, Nutt CL, Mohapatra G, Louis DN. Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas. Brain Pathology (Zurich, Switzerland). 14: 372-7. PMID 15605984  1
2004 Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion. The New England Journal of Medicine. 351: 1875-82. PMID 15509821 DOI: 10.1056/NEJMcpc049025  1
2004 Plummer NW, Gallione CJ, Srinivasan S, Zawistowski JS, Louis DN, Marchuk DA. Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. The American Journal of Pathology. 165: 1509-18. PMID 15509522 DOI: 10.1016/S0002-9440(10)63409-8  1
2004 Chiocca EA, Abbed KM, Tatter S, Louis DN, Hochberg FH, Barker F, Kracher J, Grossman SA, Fisher JD, Carson K, Rosenblum M, Mikkelsen T, Olson J, Markert J, Rosenfeld S, et al. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 958-66. PMID 15509513 DOI: 10.1016/j.ymthe.2004.07.021  1
2004 Sloan KE, Eustace BK, Stewart JK, Zehetmeier C, Torella C, Simeone M, Roy JE, Unger C, Louis DN, Ilag LL, Jay DG. CD155/PVR plays a key role in cell motility during tumor cell invasion and migration. Bmc Cancer. 4: 73. PMID 15471548 DOI: 10.1186/1471-2407-4-73  1
2004 Stephens P, Hunter C, Bignell G, Edkins S, Davies H, Teague J, Stevens C, O'Meara S, Smith R, Parker A, Barthorpe A, Blow M, Brackenbury L, Butler A, Clarke O, ... ... Louis DN, et al. Lung cancer: intragenic ERBB2 kinase mutations in tumours. Nature. 431: 525-6. PMID 15457249 DOI: 10.1038/431525b  0.32
2004 Mrak RE, Yasargil MG, Mohapatra G, Earel J, Louis DN. Atypical extraventricular neurocytoma with oligodendroglioma-like spread and an unusual pattern of chromosome 1p and 19q loss. Human Pathology. 35: 1156-9. PMID 15343519 DOI: 10.1016/j.humpath.2004.05.005  1
2004 Borowsky AD, Munn RJ, Galvez JJ, Cardiff RD, Ward JM, Morse HC, Kogan SC, Aldape KD, Louis DN, Bosenberg MW. Mouse models of human cancers (part 3). Comparative Medicine. 54: 258-70. PMID 15253271  1
2004 Megyesi JF, Kachur E, Lee DH, Zlatescu MC, Betensky RA, Forsyth PA, Okada Y, Sasaki H, Mizoguchi M, Louis DN, Cairncross JG. Imaging correlates of molecular signatures in oligodendrogliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4303-6. PMID 15240515 DOI: 10.1158/1078-0432.CCR-04-0209  1
2004 Chang SM, Seiferheld W, Curran W, Share R, Atkins J, Choucair A, Kresl J, Thoron L, Cairncross G, Gilbert M, Bahary JP, Dolinskas C, Louis DN, Bushunow P, Buckner J, et al. Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors. International Journal of Radiation Oncology, Biology, Physics. 59: 1122-6. PMID 15234047 DOI: 10.1016/j.ijrobp.2004.01.002  1
2004 Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. Journal of Neuropathology and Experimental Neurology. 63: 499-509. PMID 15198128  1
2004 Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.CAN-03-4079  1
2004 Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine. 350: 2129-39. PMID 15118073 DOI: 10.1056/NEJMoa040938  1
2004 Kiehl TR, Kalkanis SN, Louis DN. Pigmented central neurocytoma. Acta Neuropathologica. 107: 571-4. PMID 14991386 DOI: 10.1007/s00401-004-0835-1  1
2004 Yang C, Ionescu-Tiba V, Burns K, Gadd M, Zukerberg L, Louis DN, Sgroi D, Schmidt EV. The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer. The American Journal of Pathology. 164: 1031-8. PMID 14982856 DOI: 10.1016/S0002-9440(10)63190-2  1
2004 Batchelor TT, Betensky RA, Esposito JM, Pham LD, Dorfman MV, Piscatelli N, Jhung S, Rhee D, Louis DN. Age-dependent prognostic effects of genetic alterations in glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 228-33. PMID 14734474 DOI: 10.1158/1078-0432.CCR-0841-3  1
2004 Mizoguchi M, Nutt CL, Louis DN. Mutation analysis of CBL-C and SPRED3 on 19q in human glioblastoma. Neurogenetics. 5: 81-2. PMID 14618415 DOI: 10.1007/s10048-003-0164-x  1
2003 Gutmann DH, James CD, Poyhonen M, Louis DN, Ferner R, Guha A, Hariharan S, Viskochil D, Perry A. Molecular analysis of astrocytomas presenting after age 10 in individuals with NF1. Neurology. 61: 1397-400. PMID 14638962  1
2003 Betensky RA, Louis DN, Cairncross JG. Analysis of a molecular genetic neuro-oncology study with partially biased selection. Biostatistics (Oxford, England). 4: 167-78. PMID 12925514 DOI: 10.1093/biostatistics/4.2.167  1
2003 Deisboeck TS, Wakimoto H, Nestler U, Louis DN, Sehgal PK, Simon M, Chiocca EA, Hochberg FH. Development of a novel non-human primate model for preclinical gene vector safety studies. Determining the effects of intracerebral HSV-1 inoculation in the common marmoset: a comparative study. Gene Therapy. 10: 1225-33. PMID 12858187 DOI: 10.1038/sj.gt.3302003  1
2003 Kohane DS, Smith SE, Louis DN, Colombo G, Ghoroghchian P, Hunfeld NG, Berde CB, Langer R. Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres. Pain. 104: 415-21. PMID 12855352 DOI: 10.1016/S0304-3959(03)00049-6  1
2003 MacCollin M, Willett C, Heinrich B, Jacoby LB, Acierno JS, Perry A, Louis DN. Familial schwannomatosis: exclusion of the NF2 locus as the germline event. Neurology. 60: 1968-74. PMID 12821741  1
2003 Hampl JA, Camp SM, Mydlarz WK, Hampl M, Ichikawa T, Chiocca EA, Louis DN, Sena-Esteves M, Breakefield XO. Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors. Human Gene Therapy. 14: 611-26. PMID 12804144 DOI: 10.1089/104303403321618137  1
2003 Nutt CL, Mani DR, Betensky RA, Tamayo P, Cairncross JG, Ladd C, Pohl U, Hartmann C, McLaughlin ME, Batchelor TT, Black PM, von Deimling A, Pomeroy SL, Golub TR, Louis DN. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Research. 63: 1602-7. PMID 12670911  1
2003 Braaten KM, Betensky RA, de Leval L, Okada Y, Hochberg FH, Louis DN, Harris NL, Batchelor TT. BCL-6 expression predicts improved survival in patients with primary central nervous system lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1063-9. PMID 12631608  1
2003 Reifenberger G, Louis DN. Oligodendroglioma: toward molecular definitions in diagnostic neuro-oncology. Journal of Neuropathology and Experimental Neurology. 62: 111-26. PMID 12578221  1
2003 Okada Y, Hurwitz EE, Esposito JM, Brower MA, Nutt CL, Louis DN. Selection pressures of TP53 mutation and microenvironmental location influence epidermal growth factor receptor gene amplification in human glioblastomas. Cancer Research. 63: 413-6. PMID 12543796  1
2003 Heinrich B, Hartmann C, Stemmer-Rachamimov AO, Louis DN, MacCollin M. Multiple meningiomas: Investigating the molecular basis of sporadic and familial forms. International Journal of Cancer. Journal International Du Cancer. 103: 483-8. PMID 12478663 DOI: 10.1002/ijc.10840  1
2002 Lam P, Hui KM, Wang Y, Allen PD, Louis DN, Yuan CJ, Breakefield XO. Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors. Human Gene Therapy. 13: 2147-59. PMID 12542846 DOI: 10.1089/104303402320987842  1
2002 Rabinov JD, Lee PL, Barker FG, Louis DN, Harsh GR, Cosgrove GR, Chiocca EA, Thornton AF, Loeffler JS, Henson JW, Gonzalez RG. In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience. Radiology. 225: 871-9. PMID 12461273 DOI: 10.1148/radiol.2253010997  1
2002 Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, et al. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 21: 7453-63. PMID 12386807 DOI: 10.1038/sj.onc.1205936  1
2002 Hartmann C, Johnk L, Kitange G, Wu Y, Ashworth LK, Jenkins RB, Louis DN. Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19. Cancer Research. 62: 4100-8. PMID 12124348  1
2002 Mueller W, Hartmann C, Hoffmann A, Lanksch W, Kiwit J, Tonn J, Veelken J, Schramm J, Weller M, Wiestler OD, Louis DN, von Deimling A. Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets. The American Journal of Pathology. 161: 313-9. PMID 12107116 DOI: 10.1016/S0002-9440(10)64183-1  1
2002 Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T. Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell. 1: 157-68. PMID 12086874 DOI: 10.1016/S1535-6108(02)00029-6  1
2002 Louis DN, Pomeroy SL, Cairncross JG. Focus on central nervous system neoplasia. Cancer Cell. 1: 125-8. PMID 12086870 DOI: 10.1016/S1535-6108(02)00040-5  1
2002 Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 1: 269-77. PMID 12086863 DOI: 10.1016/S1535-6108(02)00046-6  1
2002 Okada Y, Nishikawa R, Matsutani M, Louis DN. Hypomethylated X chromosome gain and rare isochromosome 12p in diverse intracranial germ cell tumors. Journal of Neuropathology and Experimental Neurology. 61: 531-8. PMID 12071636  1
2002 Betensky RA, Louis DN, Cairncross JG. Influence of unrecognized molecular heterogeneity on randomized clinical trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 2495-9. PMID 12011127 DOI: 10.1200/JCO.2002.06.140  1
2002 Hartmann C, Johnk L, Sasaki H, Jenkins RB, Louis DN. Novel PLA2G4C polymorphism as a molecular diagnostic assay for 19q loss in human gliomas. Brain Pathology (Zurich, Switzerland). 12: 178-82. PMID 11958371  1
2002 Schmidt MC, Antweiler S, Urban N, Mueller W, Kuklik A, Meyer-Puttlitz B, Wiestler OD, Louis DN, Fimmers R, von Deimling A. Impact of genotype and morphology on the prognosis of glioblastoma. Journal of Neuropathology and Experimental Neurology. 61: 321-8. PMID 11939587  1
2002 Sasaki H, Betensky RA, Cairncross JG, Louis DN. DMBT1 polymorphisms: relationship to malignant glioma tumorigenesis. Cancer Research. 62: 1790-6. PMID 11912156  1
2002 Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK. The WHO classification of tumors of the nervous system. Journal of Neuropathology and Experimental Neurology. 61: 215-25; discussion 2. PMID 11895036  1
2002 Li Y, Betensky RA, Louis DN, Cairncross JG. The use of frailty hazard models for unrecognized heterogeneity that interacts with treatment: considerations of efficiency and power. Biometrics. 58: 232-6. PMID 11890320  1
2002 Sasaki H, Zlatescu MC, Betensky RA, Johnk LB, Cutone AN, Cairncross JG, Louis DN. Histopathological-molecular genetic correlations in referral pathologist-diagnosed low-grade "oligodendroglioma". Journal of Neuropathology and Experimental Neurology. 61: 58-63. PMID 11829344  1
2002 Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, ... ... Louis DN, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 415: 436-42. PMID 11807556 DOI: 10.1038/415436a  1
2002 Smith ER, Ott M, Wain J, Louis DN, Chiocca EA. Massive growth of a meningioma into the brachial plexus and thoracic cavity after intraspinal and supraclavicular resection. Case report and review of the literature. Journal of Neurosurgery. 96: 107-11. PMID 11795697  1
2002 Kohane DS, Lipp M, Kinney RC, Anthony DC, Louis DN, Lotan N, Langer R. Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium. Journal of Biomedical Materials Research. 59: 450-9. PMID 11774302 DOI: 10.1002/jbm.1261  1
2001 Wong AJ, Padarathsingh M, Louis DN, Rempel S, Ladisch S, Gladson C. New approaches to the molecular biology, classification, and therapy of nervous system tumors: a workshop of the National Institutes of Health Pathology B study section. The American Journal of Pathology. 159: 1971-4. PMID 11696458  1
2001 Primavera J, Nikas DC, Zamani AA, Shafman T, Alexander E, De Girolami U, Louis DN. Clear cell pleomorphic xanthoastrocytoma: case report. Acta Neuropathologica. 102: 404-8. PMID 11603818  1
2001 Zlatescu MC, TehraniYazdi A, Sasaki H, Megyesi JF, Betensky RA, Louis DN, Cairncross JG. Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms. Cancer Research. 61: 6713-5. PMID 11559541  1
2001 Louis DN, Holland EC, Cairncross JG. Glioma classification: a molecular reappraisal. The American Journal of Pathology. 159: 779-86. PMID 11549567 DOI: 10.1016/S0002-9440(10)61750-6  1
2001 Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM. Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 10851-6. PMID 11526205 DOI: 10.1073/pnas.181340798  1
2001 Lu X, Magrane G, Yin C, Louis DN, Gray J, Van Dyke T. Selective inactivation of p53 facilitates mouse epithelial tumor progression without chromosomal instability. Molecular and Cellular Biology. 21: 6017-30. PMID 11486039 DOI: 10.1128/MCB.21.17.6017-6030.2001  1
2001 Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes & Development. 15: 1913-25. PMID 11485986 DOI: 10.1101/gad.903001  1
2001 Blakley P, Louis DN, Short MP, MacCollin M. A clinical study of patients with multiple isolated neurofibromas. Journal of Medical Genetics. 38: 485-8. PMID 11476067  1
2001 Niida Y, Stemmer-Rachamimov AO, Logrip M, Tapon D, Perez R, Kwiatkowski DJ, Sims K, MacCollin M, Louis DN, Ramesh V. Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions. American Journal of Human Genetics. 69: 493-503. PMID 11468687 DOI: 10.1086/321972  1
2001 Sasaki H, Zlatescu MC, Betensky RA, Ino Y, Cairncross JG, Louis DN. PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosis. The American Journal of Pathology. 159: 359-67. PMID 11438483 DOI: 10.1016/S0002-9440(10)61702-6  1
2001 Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA. Malignant glioma: genetics and biology of a grave matter. Genes & Development. 15: 1311-33. PMID 11390353 DOI: 10.1101/gad.891601  1
2001 Ino Y, Betensky RA, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Ramsay DA, Cairncross JG, Louis DN. Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 839-45. PMID 11309331  1
2001 Murthy V, Stemmer-Rachamimov AO, Haddad LA, Roy JE, Cutone AN, Beauchamp RL, Smith N, Louis DN, Ramesh V. Developmental expression of the tuberous sclerosis proteins tuberin and hamartin. Acta Neuropathologica. 101: 202-10. PMID 11307618  1
2001 Campen R, Mankin H, Louis DN, Hirano M, Maccollin M. Familial occurrence of adiposis dolorosa. Journal of the American Academy of Dermatology. 44: 132-6. PMID 11148491 DOI: 10.1067/mjd.2001.110872  1
2001 Stemmer-Rachamimov AO, Wiederhold T, Nielsen GP, James M, Pinney-Michalowski D, Roy JE, Cohen WA, Ramesh V, Louis DN. NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas. The American Journal of Pathology. 158: 57-62. PMID 11141479 DOI: 10.1016/S0002-9440(10)63944-2  1
2000 Park CC, Hartmann C, Folkerth R, Loeffler JS, Wen PY, Fine HA, Black PM, Shafman T, Louis DN. Systemic metastasis in glioblastoma may represent the emergence of neoplastic subclones. Journal of Neuropathology and Experimental Neurology. 59: 1044-50. PMID 11138924  1
2000 Tortosa A, Ino Y, Odell N, Swilley S, Sasaki H, Louis DN, Henson JW. Molecular genetics of radiographically defined de novo glioblastoma multiforme. Neuropathology and Applied Neurobiology. 26: 544-52. PMID 11123721 DOI: 10.1046/j.0305-1846.2000.00290.x  1
2000 Ino Y, Wahrer DC, Bell DW, Haber DA, Louis DN. Mutation analysis of the hCHK2 gene in primary human malignant gliomas. Neurogenetics. 3: 45-6. PMID 11085597  1
2000 Bauman GS, Ino Y, Ueki K, Zlatescu MC, Fisher BJ, Macdonald DR, Stitt L, Louis DN, Cairncross JG. Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas. International Journal of Radiation Oncology, Biology, Physics. 48: 825-30. PMID 11020580 DOI: 10.1016/S0360-3016(00)00703-3  1
2000 Chan AW, Tarbell NJ, Black PM, Louis DN, Frosch MP, Ancukiewicz M, Chapman P, Loeffler JS. Adult medulloblastoma: prognostic factors and patterns of relapse. Neurosurgery. 47: 623-31; discussion 6. PMID 10981749  1
2000 Misdraji J, Ino Y, Louis DN, Rosenberg AE, Chiocca EA, Harris NL. Primary lymphoma of peripheral nerve: report of four cases. The American Journal of Surgical Pathology. 24: 1257-65. PMID 10976700 DOI: 10.1097/00000478-200009000-00009  1
2000 Smith JS, Tachibana I, Lee HK, Qian J, Pohl U, Mohrenweiser HW, Borell TJ, Hosek SM, Soderberg CL, von Deimling A, Perry A, Scheithauer BW, Louis DN, Jenkins RB. Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers. Genes, Chromosomes & Cancer. 29: 16-25. PMID 10918389 DOI: 10.1002/1098-2264(2000)9999:9999<::AID-GCC1007>3.0.CO;2-I  1
2000 von Deimling A, Fimmers R, Schmidt MC, Bender B, Fassbender F, Nagel J, Jahnke R, Kaskel P, Duerr EM, Koopmann J, Maintz D, Steinbeck S, Wick W, Platten M, Müller DJ, et al. Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors. Journal of Neuropathology and Experimental Neurology. 59: 544-58. PMID 10850867  1
2000 Cavenee WK. High-grade gliomas with chromosome 1p loss. Journal of Neurosurgery. 92: 1080-1. PMID 10839286  1
2000 Ino Y, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Jhung S, Ramsay DA, von Deimling A, Louis DN, Cairncross JG. Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss. Journal of Neurosurgery. 92: 983-90. PMID 10839259 DOI: 10.3171/jns.2000.92.6.0983  1
2000 Møller MB, Kania PW, Ino Y, Gerdes AM, Nielsen O, Louis DN, Skjødt K, Pedersen NT. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A. Leukemia. 14: 898-904. PMID 10803523  1
2000 Harsh GR, Deisboeck TS, Louis DN, Hilton J, Colvin M, Silver JS, Qureshi NH, Kracher J, Finkelstein D, Chiocca EA, Hochberg FH. Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study. Journal of Neurosurgery. 92: 804-11. PMID 10794295 DOI: 10.3171/jns.2000.92.5.0804  1
2000 Ikeda K, Wakimoto H, Ichikawa T, Jhung S, Hochberg FH, Louis DN, Chiocca EA. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant. Journal of Virology. 74: 4765-75. PMID 10775615 DOI: 10.1128/JVI.74.10.4765-4775.2000  1
2000 Qureshi NH, Bankiewicz KS, Louis DN, Hochberg FH, Chiocca EA, Harsh GR. Multicolumn infusion of gene therapy cells into human brain tumors: technical report. Neurosurgery. 46: 663-8; discussion 66. PMID 10719863  1
2000 Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB. A transcript map of the chromosome 19q-arm glioma tumor suppressor region. Genomics. 64: 44-50. PMID 10708517 DOI: 10.1006/geno.1999.6101  1
2000 Pohl U, Smith JS, Tachibana I, Ueki K, Lee HK, Ramaswamy S, Wu Q, Mohrenweiser HW, Jenkins RB, Louis DN. EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins. Genomics. 63: 255-62. PMID 10673336 DOI: 10.1006/geno.1999.6087  1
2000 Henson JW, Thornton AF, Louis DN. Spinal cord astrocytoma: response to PCV chemotherapy. Neurology. 54: 518-20. PMID 10668731  1
2000 Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Molecular and Cellular Biology. 20: 1436-47. PMID 10648628 DOI: 10.1128/MCB.20.4.1436-1447.2000  1
1999 Nielsen GP, Stemmer-Rachamimov AO, Ino Y, Moller MB, Rosenberg AE, Louis DN. Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. The American Journal of Pathology. 155: 1879-84. PMID 10595918 DOI: 10.1016/S0002-9440(10)65507-1  1
1999 Sahoo T, Johnson EW, Thomas JW, Kuehl PM, Jones TL, Dokken CG, Touchman JW, Gallione CJ, Lee-Lin SQ, Kosofsky B, Kurth JH, Louis DN, Mettler G, Morrison L, Gil-Nagel A, et al. Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1). Human Molecular Genetics. 8: 2325-33. PMID 10545614 DOI: 10.1093/hmg/8.12.2325  1
1999 Peters N, Smith JS, Tachibana I, Lee HK, Pohl U, Portier BP, Louis DN, Jenkins RB. The human glia maturation factor-gamma gene: genomic structure and mutation analysis in gliomas with chromosome 19q loss. Neurogenetics. 2: 163-6. PMID 10541589 DOI: 10.1007/s100480050077  1
1999 Pohl U, Cairncross JG, Louis DN. Homozygous deletions of the CDKN2C/p18INK4C gene on the short arm of chromosome 1 in anaplastic oligodendrogliomas. Brain Pathology (Zurich, Switzerland). 9: 639-43. PMID 10517502  1
1999 Castells A, Ino Y, Louis DN, Ramesh V, Gusella JF, Rustgi AK. Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer. Gastroenterology. 117: 831-7. PMID 10500065 DOI: 10.1016/S0016-5085(99)70341-0  1
1999 Nielsen GP, Stemmer-Rachamimov AO, Shaw J, Roy JE, Koh J, Louis DN. Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 1137-43. PMID 10496532  1
1999 Henson JW, Louis DN. Edward Peirson Richardson Jr (1918-1998) and the discovery of PML. Journal of Neurovirology. 5: 325-6. PMID 10463854  1
1999 Ino Y, Silver JS, Blazejewski L, Nishikawa R, Matsutani M, von Deimling A, Louis DN. Common regions of deletion on chromosome 22q12.3-q13.1 and 22q13.2 in human astrocytomas appear related to malignancy grade. Journal of Neuropathology and Experimental Neurology. 58: 881-5. PMID 10446812  1
1999 Ikeda K, Ichikawa T, Wakimoto H, Silver JS, Deisboeck TS, Finkelstein D, Harsh GR, Louis DN, Bartus RT, Hochberg FH, Chiocca EA. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nature Medicine. 5: 881-7. PMID 10426310 DOI: 10.1038/11320  1
1999 Taylor MD, Perry J, Zlatescu MC, Stemmer-Rachamimov AO, Ang LC, Ino Y, Schwartz M, Becker LE, Louis DN, Cairncross JG. The hPMS2 exon 5 mutation and malignant glioma. Case report. Journal of Neurosurgery. 90: 946-50. PMID 10223463 DOI: 10.3171/jns.1999.90.5.0946  1
1999 Perry JR, Louis DN, Cairncross JG. Current treatment of oligodendrogliomas. Archives of Neurology. 56: 434-6. PMID 10199331  1
1999 Møller MB, Ino Y, Gerdes AM, Skjødt K, Louis DN, Pedersen NT. Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma. Leukemia. 13: 453-9. PMID 10086736  1
1999 Vonsattel JPG, Louis DN, De Girolami U. Hommage to Edward Peirson Richardson, Jr. | Hommage a Edward Peirson Richardson, Jr. 1918-1998 Revue Neurologique. 155: 1088-1089.  1
1998 Stemmer-Rachamimov AO, Nielsen GP, Rosenberg AE, Louis DN, Jones D, Ramesh V, Gusella JF, Jacoby LB. The NF2 gene and merlin protein in human osteosarcomas. Neurogenetics. 2: 73-4. PMID 9933303 DOI: 10.1007/s100480050054  1
1998 Stemmer-Rachamimov AO, Ino Y, Lim ZY, Jacoby LB, MacCollin M, Gusella JF, Ramesh V, Louis DN. Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2. Journal of Neuropathology and Experimental Neurology. 57: 1164-7. PMID 9862639  1
1998 Brecher K, Hochberg FH, Louis DN, de la Monte S, Riskind P. Case report of unusual leukoencephalopathy preceding primary CNS lymphoma. Journal of Neurology, Neurosurgery, and Psychiatry. 65: 917-20. PMID 9854972  1
1998 Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR, Silver JS, Stark PC, Macdonald DR, Ino Y, Ramsay DA, Louis DN. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. Journal of the National Cancer Institute. 90: 1473-9. PMID 9776413  1
1998 Herrlinger U, Kramm CM, Aboody-Guterman KS, Silver JS, Ikeda K, Johnston KM, Pechan PA, Barth RF, Finkelstein D, Chiocca EA, Louis DN, Breakefield XO. Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector. Gene Therapy. 5: 809-19. PMID 9747461 DOI: 10.1038/sj.gt.3300643  1
1998 Nielsen GP, Burns KL, Rosenberg AE, Louis DN. CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations. The American Journal of Pathology. 153: 159-63. PMID 9665476 DOI: 10.1016/S0002-9440(10)65556-3  1
1998 Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG, Iliopoulos O. The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Molecular Cell. 1: 959-68. PMID 9651579  1
1998 Duerr EM, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, Louis DN, Schramm J, Wiestler OD, Parsons R, Eng C, von Deimling A. PTEN mutations in gliomas and glioneuronal tumors. Oncogene. 16: 2259-64. PMID 9619835 DOI: 10.1038/sj.onc.1201756  0.52
1998 Burns KL, Ueki K, Jhung SL, Koh J, Louis DN. Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas. Journal of Neuropathology and Experimental Neurology. 57: 122-30. PMID 9600204  1
1998 Cobbers JM, Wolter M, Reifenberger J, Ring GU, Jessen F, An HX, Niederacher D, Schmidt EE, Ichimura K, Floeth F, Kirsch L, Borchard F, Louis DN, Collins VP, Reifenberger G. Frequent inactivation of CDKN2A and rare mutation of TP53 in PCNSL. Brain Pathology (Zurich, Switzerland). 8: 263-76. PMID 9546285  1
1998 Husain N, Chiocca EA, Rainov N, Louis DN, Zervas NT. Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines. Acta Neuropathologica. 95: 287-90. PMID 9542594  0.32
1998 Bakshi R, Glass J, Louis DN, Hochberg FH. Magnetic resonance imaging features of solitary inflammatory brain masses. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 8: 8-14. PMID 9442584  1
1997 Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN. ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3. Neurogenetics. 1: 31-6. PMID 10735272  1
1997 Herrlinger U, Kramm CM, Johnston KM, Louis DN, Finkelstein D, Reznikoff G, Dranoff G, Breakefield XO, Yu JS. Vaccination for experimental gliomas using GM-CSF-transduced glioma cells. Cancer Gene Therapy. 4: 345-52. PMID 9408604  1
1997 Stemmer-Rachamimov AO, Xu L, Gonzalez-Agosti C, Burwick JA, Pinney D, Beauchamp R, Jacoby LB, Gusella JF, Ramesh V, Louis DN. Universal absence of merlin, but not other ERM family members, in schwannomas. The American Journal of Pathology. 151: 1649-54. PMID 9403715  1
1997 Mason W, Louis DN, Cairncross JG. Chemosensitive gliomas in adults: which ones and why? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 15: 3423-6. PMID 9396392  0.68
1997 Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN. Chromosomal localization to 19q13.3, partial genomic structure and 5' cDNA sequence of the human symplekin gene. Somatic Cell and Molecular Genetics. 23: 229-31. PMID 9330635  1
1997 Maintz D, Fiedler K, Koopmann J, Rollbrocker B, Nechev S, Lenartz D, Stangl AP, Louis DN, Schramm J, Wiestler OD, von Deimling A. Molecular genetic evidence for subtypes of oligoastrocytomas. Journal of Neuropathology and Experimental Neurology. 56: 1098-104. PMID 9329453  0.52
1997 Meyer-Puttlitz B, Hayashi Y, Waha A, Rollbrocker B, Boström J, Wiestler OD, Louis DN, Reifenberger G, von Deimling A. Molecular genetic analysis of giant cell glioblastomas. The American Journal of Pathology. 151: 853-7. PMID 9284834  0.52
1997 Hsu DW, Louis DN, Efird JT, Hedley-Whyte ET. Use of MIB-1 (Ki-67) immunoreactivity in differentiating grade II and grade III gliomas. Journal of Neuropathology and Experimental Neurology. 56: 857-65. PMID 9258255  1
1997 Stemmer-Rachamimov AO, Louis DN. Histopathologic and immunohistochemical prognostic factors in malignant gliomas. Current Opinion in Oncology. 9: 230-4. PMID 9229144  1
1997 Ono Y, Tamiya T, Ichikawa T, Matsumoto K, Furuta T, Ohmoto T, Akiyama K, Seki S, Ueki K, Louis DN. Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression. Acta Neuropathologica. 94: 21-7. PMID 9224526 DOI: 10.1007/s004010050667  1
1997 Hayashi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A. Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathology (Zurich, Switzerland). 7: 871-5. PMID 9217972  1
1997 Platten M, Meyer-Puttlitz B, Blümcke I, Waha A, Wolf HK, Nöthen MM, Louis DN, Sampson JR, von Deimling A. A novel splice site associated polymorphism in the tuberous sclerosis 2 (TSC2) gene may predispose to the development of sporadic gangliogliomas. Journal of Neuropathology and Experimental Neurology. 56: 806-10. PMID 9210877  1
1997 Stemmer-Rachamimov AO, Gonzalez-Agosti C, Xu L, Burwick JA, Beauchamp R, Pinney D, Louis DN, Ramesh V. Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system. Journal of Neuropathology and Experimental Neurology. 56: 735-42. PMID 9184664  1
1997 Louis DN. A molecular genetic model of astrocytoma histopathology. Brain Pathology (Zurich, Switzerland). 7: 755-64. PMID 9161727  1
1997 Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. Journal of Neuropathology and Experimental Neurology. 56: 485-9. PMID 9143261  1
1997 Listernick R, Louis DN, Packer RJ, Gutmann DH. Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force. Annals of Neurology. 41: 143-9. PMID 9029062 DOI: 10.1002/ana.410410204  1
1996 Rosenberg JE, Lisle DK, Burwick JA, Ueki K, von Deimling A, Mohrenweiser HW, Louis DN. Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene. 13: 2483-5. PMID 8957092  1
1996 Ono Y, Tamiya T, Ichikawa T, Kunishio K, Matsumoto K, Furuta T, Ohmoto T, Ueki K, Louis DN. Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices. Journal of Neuropathology and Experimental Neurology. 55: 1026-31. PMID 8857999  1
1996 Paulus W, Lisle DK, Tonn JC, Wolf HK, Roggendorf W, Reeves SA, Louis DN. Molecular genetic alterations in pleomorphic xanthoastrocytoma. Acta Neuropathologica. 91: 293-7. PMID 8834542 DOI: 10.1007/s004010050428  1
1996 Ono Y, Ueki K, Joseph JT, Louis DN. Homozygous deletions of the CDKN2/p16 gene in dural hemangiopericytomas. Acta Neuropathologica. 91: 221-5. PMID 8834533 DOI: 10.1007/s004010050419  1
1996 Kim L, Hochberg FH, Thornton AF, Harsh GR, Patel H, Finkelstein D, Louis DN. Procarbazine, lomustine, and vincristine (PCV) chemotherapy for grade III and grade IV oligoastrocytomas. Journal of Neurosurgery. 85: 602-7. PMID 8814163 DOI: 10.3171/jns.1996.85.4.0602  0.4
1996 Rollbrocker B, Waha A, Louis DN, Wiestler OD, von Deimling A. Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme. Acta Neuropathologica. 92: 70-4. PMID 8811128  0.52
1996 Rainov NG, Kramm CM, Aboody-Guterman K, Chase M, Ueki K, Louis DN, Harsh GR, Chiocca A, Breakefield XO. Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm. Cancer Gene Therapy. 3: 99-106. PMID 8729908  1
1996 Platten M, Giordano MJ, Dirven CM, Gutmann DH, Louis DN. Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas. The American Journal of Pathology. 149: 621-7. PMID 8702000  1
1996 Reeves SA, Ueki K, Sinha B, Difiglia M, Louis DN. Regional expression and subcellular localization of the tyrosine-specific phosphatase SH-PTP2 in the adult human nervous system. Neuroscience. 71: 1037-42. PMID 8684607 DOI: 10.1016/0306-4522(95)00491-2  1
1996 Chou D, Miyashita T, Mohrenweiser HW, Ueki K, Kastury K, Druck T, von Deimling A, Huebner K, Reed JC, Louis DN. The BAX gene maps to the glioma candidate region at 19q13.3, but is not altered in human gliomas. Cancer Genetics and Cytogenetics. 88: 136-40. PMID 8640722 DOI: 10.1016/0165-4608(95)00341-X  1
1996 Cramer SC, Glaspy JA, Efird JT, Louis DN. Chronic lymphocytic leukemia and the central nervous system: a clinical and pathological study. Neurology. 46: 19-25. PMID 8559372  0.52
1996 Hermanson M, Funa K, Koopmann J, Maintz D, Waha A, Westermark B, Heldin CH, Wiestler OD, Louis DN, von Deimling A, Nistér M. Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas. Cancer Research. 56: 164-71. PMID 8548759  0.52
1996 Ueki K, Ono Y, Henson JW, Efird JT, von Deimling A, Louis DN. CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Research. 56: 150-3. PMID 8548755  1
1995 Johnson EW, Iyer LM, Rich SS, Orr HT, Gil-Nagel A, Kurth JH, Zabramski JM, Marchuk DA, Weissenbach J, Clericuzio CL, Davis LE, Hart BL, Gusella JF, Kosofsky BE, Louis DN, et al. Refined localization of the cerebral cavernous malformation gene (CCM1) to a 4-cM interval of chromosome 7q contained in a well-defined YAC contig. Genome Research. 5: 368-80. PMID 8750196  1
1995 Yong WH, Ueki K, Chou D, Reeves SA, von Deimling A, Gusella JF, Mohrenweiser HW, Buckler AJ, Louis DN. Cloning of a highly conserved human protein serine-threonine phosphatase gene from the glioma candidate region on chromosome 19q13.3. Genomics. 29: 533-6. PMID 8666404 DOI: 10.1006/geno.1995.9972  1
1995 von Deimling A, Louis DN, Wiestler OD. Molecular pathways in the formation of gliomas. Glia. 15: 328-38. PMID 8586467 DOI: 10.1002/glia.440150312  0.52
1995 Marchuk DA, Gallione CJ, Morrison LA, Clericuzio CL, Hart BL, Kosofsky BE, Louis DN, Gusella JF, Davis LE, Prenger VL. A locus for cerebral cavernous malformations maps to chromosome 7q in two families. Genomics. 28: 311-4. PMID 8530042 DOI: 10.1006/geno.1995.1147  1
1995 Alderson LM, Castleberg RL, Harsh GR, Louis DN, Henson JW. Human gliomas with wild-type p53 express bcl-2. Cancer Research. 55: 999-1001. PMID 7867012  0.52
1995 Kraus JA, Koopmann J, Kaskel P, Maintz D, Brandner S, Schramm J, Louis DN, Wiestler OD, von Deimling A. Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. Journal of Neuropathology and Experimental Neurology. 54: 91-5. PMID 7815084  1
1995 Raffel C, Ueki K, Harsh GR, Louis DN. The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor. Neurosurgery. 36: 971-4; discussion 97. PMID 7791990  1
1995 Weissmann DJ, Ferry JA, Harris NL, Louis DN, Delmonico F, Spiro I. Posttransplantation lymphoproliferative disorders in solid organ recipients are predominantly aggressive tumors of host origin. American Journal of Clinical Pathology. 103: 748-55. PMID 7785662  0.4
1995 von Deimling A, Kraus JA, Stangl AP, Wellenreuther R, Lenartz D, Schramm J, Louis DN, Ramesh V, Gusella JF, Wiestler OD. Evidence for subarachnoid spread in the development of multiple meningiomas. Brain Pathology (Zurich, Switzerland). 5: 11-4. PMID 7767486  1
1995 Wellenreuther R, Kraus JA, Lenartz D, Menon AG, Schramm J, Louis DN, Ramesh V, Gusella JF, Wiestler OD, von Deimling A. Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma. The American Journal of Pathology. 146: 827-32. PMID 7717450  1
1995 Reeves SA, Rubio MP, Louis DN. General method for PCR amplification and direct sequencing of mRNA differential display products. Biotechniques. 18: 18-20. PMID 7702844  1
1995 Louis DN, Ramesh V, Gusella JF. Neuropathology and molecular genetics of neurofibromatosis 2 and related tumors. Brain Pathology (Zurich, Switzerland). 5: 163-72. PMID 7670657  0.32
1995 Louis DN, von Deimling A. Hereditary tumor syndromes of the nervous system: overview and rare syndromes. Brain Pathology (Zurich, Switzerland). 5: 145-51. PMID 7670655  0.52
1995 Yong WH, Chou D, Ueki K, Harsh GR, von Deimling A, Gusella JF, Mohrenweiser HW, Louis DN. Chromosome 19q deletions in human gliomas overlap telomeric to D19S219 and may target a 425 kb region centromeric to D19S112. Journal of Neuropathology and Experimental Neurology. 54: 622-6. PMID 7666049  1
1995 Yong WH, Raffel C, von Deimling A, Louis DN. The APC gene in Turcot's syndrome. The New England Journal of Medicine. 333: 524. PMID 7662026 DOI: 10.1056/NEJM199508243330817  1
1995 Koopmann J, Maintz D, Schild S, Schramm J, Louis DN, Wiestler OD, von Deimling A. Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours. British Journal of Cancer. 72: 1230-3. PMID 7577473  0.52
1995 Joseph JT, Lisle DK, Jacoby LB, Paulus W, Barone R, Cohen ML, Roggendorf WH, Bruner JM, Gusella JF, Louis DN. NF2 gene analysis distinguishes hemangiopericytoma from meningioma. The American Journal of Pathology. 147: 1450-5. PMID 7485407  1
1995 Louis DN, Gusella JF. A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends in Genetics : Tig. 11: 412-5. PMID 7482768 DOI: 10.1016/S0168-9525(00)89125-8  1
1994 Louis DN. The p53 gene and protein in human brain tumors. Journal of Neuropathology and Experimental Neurology. 53: 11-21. PMID 8301315  1
1994 Rubio MP, Correa KM, Ramesh V, MacCollin MM, Jacoby LB, von Deimling A, Gusella JF, Louis DN. Analysis of the neurofibromatosis 2 gene in human ependymomas and astrocytomas. Cancer Research. 54: 45-7. PMID 8261460  0.52
1994 von Deimling A, Nagel J, Bender B, Lenartz D, Schramm J, Louis DN, Wiestler OD. Deletion mapping of chromosome 19 in human gliomas. International Journal of Cancer. Journal International Du Cancer. 57: 676-80. PMID 8194874  0.52
1994 Aronen HJ, Gazit IE, Louis DN, Buchbinder BR, Pardo FS, Weisskoff RM, Harsh GR, Cosgrove GR, Halpern EF, Hochberg FH. Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology. 191: 41-51. PMID 8134596 DOI: 10.1148/radiology.191.1.8134596  1
1994 Rubio MP, Correa KM, Ueki K, Mohrenweiser HW, Gusella JF, von Deimling A, Louis DN. The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC. Cancer Research. 54: 4760-3. PMID 8062276  1
1994 Miller DC, Hochberg FH, Harris NL, Gruber ML, Louis DN, Cohen H. Pathology with clinical correlations of primary central nervous system non-Hodgkin's lymphoma. The Massachusetts General Hospital experience 1958-1989. Cancer. 74: 1383-97. PMID 8055462  0.4
1994 von Deimling A, Louis DN, Schramm J, Wiestler OD. Astrocytic gliomas: characterization on a molecular genetic basis. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 135: 33-42. PMID 8047695  0.52
1994 Golden JA, Louis DN. Images in clinical medicine. Acute bacterial meningitis. The New England Journal of Medicine. 331: 364. PMID 8028617 DOI: 10.1056/NEJM199408113310605  1
1994 Jacoby LB, MacCollin M, Louis DN, Mohney T, Rubio MP, Pulaski K, Trofatter JA, Kley N, Seizinger B, Ramesh V. Exon scanning for mutation of the NF2 gene in schwannomas. Human Molecular Genetics. 3: 413-9. PMID 8012353  0.44
1994 Henson JW, Schnitker BL, Correa KM, von Deimling A, Fassbender F, Xu HJ, Benedict WF, Yandell DW, Louis DN. The retinoblastoma gene is involved in malignant progression of astrocytomas. Annals of Neurology. 36: 714-21. PMID 7979217 DOI: 10.1002/ana.410360505  0.52
1994 Louis DN, Seizinger BR. Genetic basis of neurological tumours. BaillièRe's Clinical Neurology. 3: 335-52. PMID 7952851  1
1994 Ueki K, Richardson EP, Henson JW, Louis DN. In situ polymerase chain reaction demonstration of JC virus in progressive multifocal leukoencephalopathy, including an index case. Annals of Neurology. 36: 670-3. PMID 7944303 DOI: 10.1002/ana.410360421  1
1994 Tatter SB, Ogilvy CS, Golden JA, Ojemann RG, Louis DN. Third ventricular xanthogranulomas clinically and radiologically mimicking colloid cysts. Report of two cases. Journal of Neurosurgery. 81: 605-9. PMID 7931596 DOI: 10.3171/jns.1994.81.4.0605  0.92
1994 Xu L, Sgroi D, Sterner CJ, Beauchamp RL, Pinney DM, Keel S, Ueki K, Rutter JL, Buckler AJ, Louis DN. Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas. Cancer Research. 54: 5262-4. PMID 7923151  1
1994 MacCollin M, Ramesh V, Jacoby LB, Louis DN, Rubio MP, Pulaski K, Trofatter JA, Short MP, Bove C, Eldridge R. Mutational analysis of patients with neurofibromatosis 2. American Journal of Human Genetics. 55: 314-20. PMID 7913580  1
1994 Ueki K, Rubio MP, Ramesh V, Correa KM, Rutter JL, von Deimling A, Buckler AJ, Gusella JF, Louis DN. MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p. Human Molecular Genetics. 3: 1841-5. PMID 7849711  1
1993 Louis DN, von Deimling A, Chung RY, Rubio MP, Whaley JM, Eibl RH, Ohgaki H, Wiestler OD, Thor AD, Seizinger BR. Comparative study of p53 gene and protein alterations in human astrocytic tumors. Journal of Neuropathology and Experimental Neurology. 52: 31-8. PMID 8381161  0.52
1993 Rubio MP, von Deimling A, Yandell DW, Wiestler OD, Gusella JF, Louis DN. Accumulation of wild type p53 protein in human astrocytomas. Cancer Research. 53: 3465-7. PMID 8339248  0.52
1993 Burnstine MA, Levin LA, Louis DN, Hedley-Whyte ET, Kupsky WJ, Doepner D, Albert DM. Nucleolar organizer regions in optic gliomas. Brain : a Journal of Neurology. 116: 1465-76. PMID 8293281  1
1993 von Deimling A, von Ammon K, Schoenfeld D, Wiestler OD, Seizinger BR, Louis DN. Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathology (Zurich, Switzerland). 3: 19-26. PMID 8269081  0.52
1993 von Deimling A, Louis DN, Menon AG, von Ammon K, Petersen I, Ellison D, Wiestler OD, Seizinger BR. Deletions on the long arm of chromosome 17 in pilocytic astrocytoma. Acta Neuropathologica. 86: 81-5. PMID 8103960  0.52
1993 Louis DN, Rubio MP, Correa KM, Gusella JF, von Deimling A. Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens. Journal of Neuropathology and Experimental Neurology. 52: 507-15. PMID 8103086  0.52
1993 Centeno BA, Louis DN, Kupsky WJ, Preffer FI, Sobel RA. The AgNOR technique, PCNA immunohistochemistry, and DNA ploidy in the evaluation of choroid plexus biopsy specimens. American Journal of Clinical Pathology. 100: 690-6. PMID 7902669  1
1993 von Deimling A, Bender B, Louis DN, Wiestler OD. A rapid and non-radioactive PCR based assay for the detection of allelic loss in human gliomas. Neuropathology and Applied Neurobiology. 19: 524-9. PMID 7510049  0.52
1992 Louis DN, Arriagada PV, Hyman BT, Hedley-Whyte ET. Olfactory dysgenesis or hypoplasia: a variant in the arhinencephaly spectrum? Neurology. 42: 179-82. PMID 1734299  1
1992 Glass J, Hochberg FH, Gruber ML, Louis DN, Smith D, Rattner B. The treatment of oligodendrogliomas and mixed oligodendroglioma-astrocytomas with PCV chemotherapy. Journal of Neurosurgery. 76: 741-5. PMID 1564535 DOI: 10.3171/jns.1992.76.5.0741  0.4
1992 Louis DN, Meehan SM, Ferrante RJ, Hedley-Whyte ET. Use of the silver nucleolar organizer region (AgNOR) technique in the differential diagnosis of central nervous system neoplasia. Journal of Neuropathology and Experimental Neurology. 51: 150-7. PMID 1538239  1
1992 Louis DN, von Deimling A, Dickersin GR, Dooling EC, Seizinger BR. Desmoplastic cerebral astrocytomas of infancy: a histopathologic, immunohistochemical, ultrastructural, and molecular genetic study. Human Pathology. 23: 1402-9. PMID 1468778  0.52
1992 Louis DN, von Deimling A, Seizinger BR. A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens. The American Journal of Pathology. 141: 777-82. PMID 1415476  0.52
1992 von Deimling A, von Deimling F, Louis DN, Trofatter J, Gusella JF, Seizinger BR. A RsaI polymorphism in the ERCC2 locus. Human Molecular Genetics. 1: 355. PMID 1363878  0.52
1992 von Deimling A, Louis DN, von Ammon K, Petersen I, Wiestler OD, Seizinger BR. Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas. Cancer Research. 52: 4277-9. PMID 1353411  0.52
1992 von Deimling A, Eibl RH, Ohgaki H, Louis DN, von Ammon K, Petersen I, Kleihues P, Chung RY, Wiestler OD, Seizinger BR. p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Research. 52: 2987-90. PMID 1349850  0.52
1992 von Deimling A, Louis DN, von Ammon K, Petersen I, Hoell T, Chung RY, Martuza RL, Schoenfeld DA, YaÅŸargil MG, Wiestler OD. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. Journal of Neurosurgery. 77: 295-301. PMID 1320666 DOI: 10.3171/jns.1992.77.2.0295  1
1991 Louis DN, Edgerton S, Thor AD, Hedley-Whyte ET. Proliferating cell nuclear antigen and Ki-67 immunohistochemistry in brain tumors: a comparative study. Acta Neuropathologica. 81: 675-9. PMID 1679278 DOI: 10.1007/BF00296379  1
1991 Arriagada PV, Louis DN, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles and olfactory dysgenesis. Lancet. 337: 559. PMID 1671925 DOI: 10.1016/0140-6736(91)91351-T  1
1990 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma: a follow-up study of sarcomatous dedifferentiation. Acta Neuropathologica. 80: 573-4. PMID 2251917 DOI: 10.1007/BF00294623  1
1990 Louis DN, Swearingen B, Linggood RM, Dickersin GR, Kretschmar C, Bhan AK, Hedley-Whyte ET. Central nervous system neurocytoma and neuroblastoma in adults--report of eight cases. Journal of Neuro-Oncology. 9: 231-8. PMID 2086738 DOI: 10.1007/BF02341154  1
1989 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma. Acta Neuropathologica. 78: 332-5. PMID 2763807 DOI: 10.1007/BF00687765  1
1989 Louis DN, Richardson EP, Dickersin GR, Petrucci DA, Rosenberg AE, Ojemann RG. Primary intracranial leiomyosarcoma. Case report. Journal of Neurosurgery. 71: 279-82. PMID 2746352 DOI: 10.3171/jns.1989.71.2.0279  0.52
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