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David N. Louis, MD - Publications

Affiliations: 
Pathology Harvard Medical School and Masssachusetts General Hospital, Boston, MA, United States 
Area:
molecular genetic basis of human brain tumors
Website:
http://pathology.hms.harvard.edu/mgh.htm

345 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Spitzer A, Gritsch S, Nomura M, Jucht A, Fortin J, Raviram R, Weisman HR, Gonzalez Castro LN, Druck N, Chanoch-Myers R, Lee JJY, Mylvaganam R, Lee Servis R, Fung JM, Lee CK, ... ... Louis DN, et al. Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma. Cancer Cell. PMID 38579724 DOI: 10.1016/j.ccell.2024.03.008  0.434
2023 Lang-Orsini M, Champion SN, Duhaime AC, Rapalino O, Hedley-Whyte ET, Louis DN, Nazarian RM. Atretic Cephalocele and Encephalocele: A single institution clinicopathological study. Journal of Cutaneous Pathology. PMID 36700349 DOI: 10.1111/cup.14399  0.599
2021 Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, ... ... Louis DN, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. PMID 33592174 DOI: 10.1016/j.cell.2021.01.022  0.579
2021 Champion SN, Duhaime AC, Hedley-Whyte ET, Louis DN, Nazarian RM. Atretic cephalocele: report of an infrequent dermatopathologic finding. Journal of Cutaneous Pathology. PMID 33470459 DOI: 10.1111/cup.13824  0.582
2020 Ellison DW, Aldape KD, Capper D, Fouladi M, Gilbert MR, Gilbertson RJ, Hawkins C, Merchant T, Pajtler K, Venneti S, Louis DN. cIMPACT-NOW Update 7: advancing the molecular classification of ependymal tumors. Brain Pathology (Zurich, Switzerland). PMID 32502305 DOI: 10.1111/Bpa.12866  0.405
2020 Louis DN, Wesseling P, Aldape K, Brat DJ, Capper D, Cree IA, Eberhart C, Figarella-Branger D, Fouladi M, Fuller GN, Giannini C, Haberler C, Hawkins C, Komori T, Kros JM, et al. cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathology (Zurich, Switzerland). PMID 32307792 DOI: 10.1111/Bpa.12832  0.383
2020 Brat DJ, Aldape K, Colman H, Figrarella-Branger D, Fuller GN, Giannini C, Holland EC, Jenkins RB, Kleinschmidt-DeMasters B, Komori T, Kros JM, Louis DN, McLean C, Perry A, Reifenberger G, et al. cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas. Acta Neuropathologica. PMID 31996992 DOI: 10.1007/S00401-020-02127-9  0.485
2019 Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Louis DN, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/J.Cell.2019.06.024  0.771
2019 Louis DN. A half century of change in diagnostic neuropathology: from the giants of yore to current brain tumor classification. Human Pathology. PMID 31302204 DOI: 10.1016/J.Humpath.2019.06.006  0.317
2019 Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, et al. Data Sets for the Reporting of Tumors of the Central Nervous System. Archives of Pathology & Laboratory Medicine. PMID 31219344 DOI: 10.5858/Arpa.2018-0565-Oa  0.493
2019 Louis DN, Ellison DW, Brat DJ, Aldape K, Capper D, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, von Deimling A, Wesseling P. cIMPACT-NOW: A practical summary of diagnostic points from Round 1 updates. Brain Pathology (Zurich, Switzerland). PMID 31038238 DOI: 10.1111/Bpa.12732  0.371
2019 Tanaka S, Batchelor TT, Iafrate AJ, Dias-Santagata D, Borger DR, Ellisen LW, Yang D, Louis DN, Cahill DP, Chi AS. PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma. Acta Neuropathologica Communications. 7: 66. PMID 31036078 DOI: 10.1186/S40478-019-0720-8  0.549
2019 Ellison DW, Hawkins C, Jones DTW, Onar-Thomas A, Pfister SM, Reifenberger G, Louis DN. cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF mutation. Acta Neuropathologica. PMID 30848347 DOI: 10.1007/S00401-019-01987-0  0.3
2019 Kubler K, Karlic R, Haradhvala NJ, Ha K, Kim J, Kuzman M, Jiao W, Gakkhar S, Mouw KW, Braunstein LZ, Elemento O, Biankin AV, Rooman I, Miller M, Nogiec CD, ... ... Louis DN, et al. Abstract 2727: The premalignant state captured in the landscape of somatic mutations can reveal the cancer cell-of-origin Cancer Research. 79: 2727-2727. DOI: 10.1158/1538-7445.Am2019-2727  0.32
2018 Fritchie K, Jensch K, Moskalev EA, Caron A, Jenkins S, Link M, Brown PD, Rodriguez FJ, Guajardo A, Brat D, Velázquez Vega JE, Perry A, Wu A, Raleigh DR, Santagata S, ... Louis DN, et al. The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. Acta Neuropathologica. PMID 30584643 DOI: 10.1007/S00401-018-1952-6  0.408
2018 Herrmann MD, Clunie DA, Fedorov A, Doyle SW, Pieper S, Klepeis V, Le LP, Mutter GL, Milstone DS, Schultz TJ, Kikinis R, Kotecha GK, Hwang DH, Andriole KP, Iafrate AJ, ... ... Louis DN, et al. Implementing the DICOM Standard for Digital Pathology. Journal of Pathology Informatics. 9: 37. PMID 30533276 DOI: 10.4103/Jpi.Jpi_42_18  0.555
2018 Bale TA, Jordan JT, Rapalino O, Ramamurthy N, Jessop N, DeWitt JC, Nardi V, Martinez-Lage Alvarez M, Frosch M, Batchelor TT, Louis DN, Iafrate AJ, Cahill DP, Lennerz JK. Financially Effective Test-Algorithm to Identify an Aggressive, EGFR-amplified Variant of IDH-Wildtype, Lower-Grade Diffuse Glioma. Neuro-Oncology. PMID 30496526 DOI: 10.1093/Neuonc/Noy201  0.576
2018 Brat DJ, Aldape K, Colman H, Holland EC, Louis DN, Jenkins RB, Kleinschmidt-DeMasters BK, Perry A, Reifenberger G, Stupp R, von Deimling A, Weller M. cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV". Acta Neuropathologica. PMID 30259105 DOI: 10.1007/S00401-018-1913-0  0.553
2018 Shirahata M, Ono T, Stichel D, Schrimpf D, Reuss DE, Sahm F, Koelsche C, Wefers A, Reinhardt A, Huang K, Sievers P, Shimizu H, Nanjo H, Kobayashi Y, Miyake Y, ... ... Louis DN, et al. Novel, improved grading system(s) for IDH-mutant astrocytic gliomas. Acta Neuropathologica. PMID 29687258 DOI: 10.1007/S00401-018-1849-4  0.584
2018 Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, ... ... Louis DN, et al. Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.). 360: 331-335. PMID 29674595 DOI: 10.1126/Science.Aao4750  0.539
2018 Louis DN. A feast of reviews about brain and pituitary tumor pathology. Brain Tumor Pathology. PMID 29666968 DOI: 10.1007/S10014-018-0315-2  0.354
2018 von Deimling A, Ono T, Shirahata M, Louis DN. Grading of Diffuse Astrocytic Gliomas: A Review of Studies Before and After the Advent of IDH Testing. Seminars in Neurology. 38: 19-23. PMID 29548048 DOI: 10.1055/S-0038-1636430  0.388
2018 Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, ... Louis DN, et al. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nature Communications. 9: 810. PMID 29476136 DOI: 10.1038/S41467-018-02826-8  0.759
2018 Fritchie K, Jensch K, Jenkins S, Link M, D Brown P, Rodriguez F, Guajardo A, Brat D, Velazquez Vega J, Perry A, Wu A, Raleigh D, Santagata S, Louis D, Brastianos P, et al. RARE-08. GRADING CONSIDERATIONS FOR MENINGEAL SOLITARY FIBROUS TUMOR/HEMANGIOPERICYTOMA Neuro-Oncology. 20: vi237-vi238. DOI: 10.1093/Neuonc/Noy148.985  0.4
2018 Louis D, Brat D, Ellison D. PATH-32. BRAIN TUMOR CLASSIFICATION UPDATES FROM cIMPACT-NOW, THE CONSORTIUM TO INFORM MOLECULAR AND PRACTICAL APPROACHES TO CNS TUMOR CLASSIFICATION Neuro-Oncology. 20: vi165-vi165. DOI: 10.1093/Neuonc/Noy148.688  0.374
2017 DeWitt JC, Jordan JT, Frosch MP, Samore WR, Iafrate AJ, Louis DN, Lennerz JK. Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations. Neuro-Oncology. PMID 29016871 DOI: 10.1093/Neuonc/Nox120  0.55
2017 DeWitt JC, Mock A, Louis DN. The 2016 WHO classification of central nervous system tumors: what neurologists need to know. Current Opinion in Neurology. PMID 28901970 DOI: 10.1097/Wco.0000000000000490  0.393
2017 Bruner JM, Louis DN, McLendon R, Rosenblum MK, Archambault WT, Most S, Tihan T. The Utility of Expert Diagnosis in Surgical Neuropathology: Analysis of Consultations Reviewed at 5 National Comprehensive Cancer Network Institutions. Journal of Neuropathology and Experimental Neurology. 76: 189-194. PMID 28395084 DOI: 10.1093/Jnen/Nlw122  0.346
2017 Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, ... ... Louis DN, et al. Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science (New York, N.Y.). 355. PMID 28360267 DOI: 10.1126/Science.Aai8478  0.652
2016 Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, ... ... Louis DN, et al. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro-Oncology. PMID 28170043 DOI: 10.1093/Neuonc/Now235  0.568
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Gregory Cairncross J, Pfister SM, Rutkowski S, et al. cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathology (Zurich, Switzerland). PMID 27997995 DOI: 10.1111/Bpa.12457  0.376
2016 Chi AS, Cahill DP, Larvie M, Louis DN. Case 38-2016. The New England Journal of Medicine. 375: 2381-2389. PMID 27974037 DOI: 10.1056/Nejmcpc1610101  0.45
2016 Louis DN, Aldape K, Brat DJ, Capper D, Ellison DW, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor TT, Cairncross JG, Pfister SM, Rutkowski S, et al. Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. Acta Neuropathologica. PMID 27909809 DOI: 10.1007/S00401-016-1646-X  0.38
2016 Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, ... ... Louis DN, et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. PMID 27806376 DOI: 10.1038/Nature20123  0.597
2016 Aldape K, Nejad R, Louis DN, Zadeh G. Integrating molecular markers into the World Health Organization classification of CNS tumors: a survey of the neuro-oncology community. Neuro-Oncology. PMID 27688263 DOI: 10.1093/Neuonc/Now181  0.349
2016 Lennerz JK, McLaughlin HM, Baron JM, Rasmussen D, Shin MS, Berners-Lee N, Batten JM, Swoboda KJ, Gala MK, Winter HS, Schmahmann JD, Sweetser DA, Boswell M, Pacula M, Stenzinger A, ... ... Louis DN, et al. Health Care Infrastructure for Financially Sustainable Clinical Genomics. The Journal of Molecular Diagnostics : Jmd. PMID 27471182 DOI: 10.1016/J.Jmoldx.2016.04.003  0.587
2016 Ostrom QT, Gittleman H, Kruchko C, Louis DN, Brat DJ, Gilbert MR, Petkov VI, Barnholtz-Sloan JS. Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying). Journal of Neuro-Oncology. PMID 27418206 DOI: 10.1007/S11060-016-2217-7  0.371
2016 Venteicher AS, Tirosh I, Hebert C, Escalante L, Martuza RL, Nahed BV, Curry WT, Cahill DP, Bernstein B, Louis DN, Regev A, Suva M. 142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis. Neurosurgery. 63: 158. PMID 27399421 DOI: 10.1227/01.Neu.0000489712.44702.0D  0.574
2016 Ho AL, Koch MJ, Tanaka S, Eichler AF, Batchelor TT, Tanboon J, Louis DN, Cahill DP, Chi AS, Curry WT. Impact of histopathological transformation and overall survival in patients with progressive anaplastic glioma. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 27279154 DOI: 10.1016/J.Jocn.2016.02.019  0.51
2016 Calle S, Louis D, Westmark R, Westmark K. Angioleiomyoma of the falx. Journal of Radiology Case Reports. 10: 8-15. PMID 27200167 DOI: 10.3941/Jrcr.V10I4.2713  0.319
2016 Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathologica. 131: 803-20. PMID 27157931 DOI: 10.1007/S00401-016-1545-1  0.435
2016 Brastianos PK, Shankar GM, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M, Jones PS, Dunn IF, Nahed BV, Romero JM, Louis DN, Getz G, et al. Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy. Journal of the National Cancer Institute. 108. PMID 26498373 DOI: 10.1093/Jnci/Djv310  0.508
2016 Filbin M, Tirosh I, Neftel C, Hovestadt V, Venteicher A, Hebert C, Shaw M, Escalante L, Pelton K, Goumnerova L, Czech T, Slavc I, Monje M, Bandopadhayay P, Nahed B, ... ... Louis D, et al. GENT-16. REDEFINING THE CELLULAR ARCHITECTURE OF ADULT AND PEDIATRIC GLIOBLASTOMAS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES Neuro-Oncology. 18: vi77-vi77. DOI: 10.1093/Neuonc/Now212.322  0.431
2015 Tanboon J, Williams EA, Louis DN. The Diagnostic Use of Immunohistochemical Surrogates for Signature Molecular Genetic Alterations in Gliomas. Journal of Neuropathology and Experimental Neurology. PMID 26671986 DOI: 10.1093/Jnen/Nlv009  0.364
2015 Cahill DP, Louis DN, Cairncross JG. Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1. Cns Oncology. PMID 26545048 DOI: 10.2217/Cns.15.32  0.601
2015 Cahill DP, Sloan AE, Nahed BV, Aldape KD, Louis DN, Ryken TC, Kalkanis SN, Olson JJ. The role of neuropathology in the management of patients with diffuse low grade glioma : A systematic review and evidence-based clinical practice guideline. Journal of Neuro-Oncology. PMID 26530263 DOI: 10.1007/S11060-015-1909-8  0.462
2015 Shankar GM, Lelic N, Gill CM, Thorner AR, Van Hummelen P, Wisoff JH, Loeffler JS, Brastianos PK, Shin JH, Borges LF, Butler WE, Zagzag D, Brody RI, Duhaime AC, Taylor MD, ... ... Louis DN, et al. BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology. Acta Neuropathologica. PMID 26487540 DOI: 10.1007/S00401-015-1492-2  0.537
2015 Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, ... ... Louis DN, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.Cd-15-0369  0.727
2015 Shankar GM, Francis JM, Rinne ML, Ramkissoon SH, Huang FW, Venteicher AS, Akama-Garren EH, Kang YJ, Lelic N, Kim JC, Brown LE, Charbonneau SK, Golby AJ, Sekhar Pedamallu C, Hoang MP, ... ... Louis DN, et al. Rapid Intraoperative Molecular Characterization of Glioma. Jama Oncology. PMID 26181761 DOI: 10.1001/Jamaoncol.2015.0917  0.72
2015 Louis DN, Feldman M, Carter AB, Dighe AS, Pfeifer JD, Bry L, Almeida JS, Saltz J, Braun J, Tomaszewski JE, Gilbertson JR, Sinard JH, Gerber GK, Galli SJ, Golden JA, et al. Computational Pathology. Archives of Pathology & Laboratory Medicine. PMID 26098131 DOI: 10.5858/Arpa.2015-0093-Sa  0.57
2015 Nigim F, Cavanaugh J, Patel AP, Curry WT, Esaki S, Kasper EM, Chi AS, Louis DN, Martuza RL, Rabkin SD, Wakimoto H. Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment. Journal of Neuropathology and Experimental Neurology. 74: 710-22. PMID 26083570 DOI: 10.1097/Nen.0000000000000210  0.327
2015 Lym RL, Ostrom QT, Kruchko C, Couce M, Brat DJ, Louis DN, Barnholtz-Sloan JS. Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011. Journal of Neuro-Oncology. 123: 43-51. PMID 25864099 DOI: 10.1007/S11060-015-1775-4  0.403
2015 Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Allen EV, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Cahill D, Curry WT, Dunn IF, Paek SH, Hummelen PV, ... ... Louis DN, et al. Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations Brain. 75: 4727-4727. DOI: 10.1158/1538-7445.Am2015-4727  0.725
2015 Venteicher A, Tirosh I, Hebert C, Escalante L, Nahed B, Cahill D, Curry W, Martuza R, Bernstein B, Louis D, Regev A, Suva M. STEM-22LARGE-SCALE SINGLE-CELL RNA-seq REVEALS A DEVELOPMENTAL CELLULAR HIERARCHY IN HUMAN OLIGODENDROGLIOMA Neuro-Oncology. 17: v212.4-v213. DOI: 10.1093/Neuonc/Nov234.22  0.551
2015 Brastianos P, Carter S, Santagata S, Cahill D, Taylor-Weiner A, Jones R, Ligon K, Tabernero J, Seoane J, Martinez Saez E, Johnson B, Choueiri T, Stemmer-Rachamimov A, Lin N, Beroukhim R, ... ... Louis D, et al. 2905 Genomic characterization of brain metastases and paired primary tumors reveals branched evolution and potential therapeutic targets European Journal of Cancer. 51: S586. DOI: 10.1016/S0959-8049(16)31622-7  0.66
2014 Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, ... ... Louis DN, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathologica Communications. 2: 167. PMID 25589003 DOI: 10.1186/S40478-014-0167-X  0.756
2014 Hainfellner J, Louis DN, Perry A, Wesseling P. Letter in response to David N. Louis et al, International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading, Brain Pathology, doi: 10.1111/bpa.12171. Brain Pathology (Zurich, Switzerland). 24: 671-2. PMID 25345897 DOI: 10.1111/Bpa.12187  0.306
2014 Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA. Computational pathology: an emerging definition. Archives of Pathology & Laboratory Medicine. 138: 1133-8. PMID 25171694 DOI: 10.5858/Arpa.2014-0034-Ed  0.555
2014 Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV, Kapur R, Shah K, Iafrate AJ, Curry WT, Loeffler JS, ... ... Louis DN, et al. Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discovery. 4: 1299-309. PMID 25139148 DOI: 10.1158/2159-8290.Cd-14-0471  0.399
2014 Panageas KS, Reiner AS, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Urgoiti GB, Wen PY, Ligon KL, et al. Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors. Neuro-Oncology. 16: 1541-6. PMID 24997140 DOI: 10.1093/Neuonc/Nou083  0.367
2014 Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, et al. International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathology (Zurich, Switzerland). 24: 429-35. PMID 24990071 DOI: 10.1111/Bpa.12171  0.387
2014 Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (New York, N.Y.). 344: 1396-401. PMID 24925914 DOI: 10.1126/Science.1254257  0.511
2014 Mordes DA, Lynch K, Campbell S, Dias-Santagata D, Nose V, Louis DN, Hoang MP. VE1 antibody immunoreactivity in normal anterior pituitary and adrenal cortex without detectable BRAF V600E mutations. American Journal of Clinical Pathology. 141: 811-5. PMID 24838325 DOI: 10.1309/Ajcp37Tlzltuaojl  0.315
2014 Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, ... ... Louis DN, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 157: 580-94. PMID 24726434 DOI: 10.1016/J.Cell.2014.02.030  0.528
2014 Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, ... ... Louis DN, et al. Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nature Genetics. 46: 161-5. PMID 24413733 DOI: 10.1038/Ng.2868  0.416
2014 Nahed BV, Sullivan JP, Madden MW, Oliveira SM, Chi AS, Springer S, Wakimoto H, Bhere D, Shah A, Spuhler P, Batchelor T, Louis DN, Toner M, Maheswaran S, Haber DA. American Brain Tumor Association Young Investigator Award 198 Circulating Tumor Cells in Patients With Glioblastoma Neurosurgery. 61: 226. DOI: 10.1227/01.Neu.0000452472.28571.08  0.394
2014 Taylor-Weiner AN, Brastianos PK, Manley PE, Jones RT, Dias-Sangata D, Thorner A, Rodriguez F, Bernardo L, Schubert L, Stewart C, Keiran M, Hahn WC, Resnick A, Louis D, Sangata S, et al. Abstract 935: Exome sequencing reveals BRAF mutations in papillary craniopharyngiomas Cancer Research. 74: 935-935. DOI: 10.1158/1538-7445.Am2014-935  0.388
2014 Sullivan JP, Nahed BV, Chi AS, Madden MN, Oliveira SM, Springer S, Wakimoto H, Bhere D, Shah K, Spuhler P, Shah AM, Louis DN, Toner M, Maheswaran S, Haber DA. Abstract 4004: Molecular characterization of circulating glioblastoma cells identifies a mesenchymal-like tumor cell subpopulation Cancer Research. 74: 4004-4004. DOI: 10.1158/1538-7445.Am2014-4004  0.434
2014 Brastianos P, Taylor-Weiner A, Manley P, Jones R, Dias-Santagata D, Thorner A, Rodriguez F, Bernardo L, Schubert L, Stewart C, Kieran M, Louis D, Getz G, Santagata S. GE-05 * EXOME SEQUENCING REVEALS BRAF MUTATIONS IN PAPILLARY CRANIOPHARYNGIOMAS Neuro-Oncology. 16: v97-v97. DOI: 10.1093/Neuonc/Nou256.5  0.404
2014 Brastianos P, Carter S, Santagata S, Taylor-Weiner A, Jones R, Van Allen E, Horowitz P, Ligon K, Cahill D, Dunn I, Van Hummelen P, Lin N, Curry W, Stemmer-Rachamimov A, Beroukhim R, ... ... Louis D, et al. BM-07 * GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS Neuro-Oncology. 16: v33-v33. DOI: 10.1093/Neuonc/Nou240.7  0.746
2013 Suvà ML, Louis DN. Next-generation molecular genetics of brain tumours. Current Opinion in Neurology. 26: 681-7. PMID 24184972 DOI: 10.1097/Wco.0000000000000027  0.358
2013 Song Y, Zhang Q, Kutlu B, Difilippantonio S, Bash R, Gilbert D, Yin C, O'Sullivan TN, Yang C, Kozlov S, Bullitt E, McCarthy KD, Kafri T, Louis DN, Miller CR, et al. Evolutionary etiology of high-grade astrocytomas. Proceedings of the National Academy of Sciences of the United States of America. 110: 17933-8. PMID 24114272 DOI: 10.1073/Pnas.1317026110  0.376
2013 Routhier CA, Mochel MC, Lynch K, Dias-Santagata D, Louis DN, Hoang MP. Comparison of 2 monoclonal antibodies for immunohistochemical detection of BRAF V600E mutation in malignant melanoma, pulmonary carcinoma, gastrointestinal carcinoma, thyroid carcinoma, and gliomas. Human Pathology. 44: 2563-70. PMID 24071017 DOI: 10.1016/J.Humpath.2013.06.018  0.342
2013 Riemenschneider MJ, Louis DN, Weller M, Hau P. Refined brain tumor diagnostics and stratified therapies: the requirement for a multidisciplinary approach. Acta Neuropathologica. 126: 21-37. PMID 23689616 DOI: 10.1007/S00401-013-1127-4  0.362
2013 Ozkumur E, Shah AM, Ciciliano JC, Emmink BL, Miyamoto DT, Brachtel E, Yu M, Chen PI, Morgan B, Trautwein J, Kimura A, Sengupta S, Stott SL, Karabacak NM, Barber TA, ... ... Louis DN, et al. Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Science Translational Medicine. 5: 179ra47. PMID 23552373 DOI: 10.1126/Scitranslmed.3005616  0.367
2013 Chi AS, Batchelor TT, Yang D, Dias-Santagata D, Borger DR, Ellisen LW, Iafrate AJ, Louis DN. BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: e233-6. PMID 23547069 DOI: 10.1200/Jco.2012.46.0220  0.31
2013 Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nature Genetics. 45: 285-9. PMID 23334667 DOI: 10.1038/Ng.2526  0.732
2013 Tanaka S, Louis DN, Curry WT, Batchelor TT, Dietrich J. Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end? Nature Reviews. Clinical Oncology. 10: 14-26. PMID 23183634 DOI: 10.1038/Nrclinonc.2012.204  0.31
2013 Tanaka S, Batchelor T, Iafrate AJ, Dias-Santagata D, Borger DR, Ellisen LW, Yang D, Louis DN, Cahill DP, Chi AS. Association of PIK3CA-activating mutations with more disseminated disease at presentation and earlier recurrence in glioblastoma. Journal of Clinical Oncology. 31: 2029-2029. DOI: 10.1200/Jco.2013.31.15_Suppl.2029  0.393
2013 Brastianos P, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon K, Hummelen PV, Ducar M, Raza A, Sunkavalli A, MacConaill L, Stemmer-Rachamimov A, Louis DN, Hahn WC, et al. Abstract 803: Genomic sequencing of meningiomas reveals oncogenic SMO and AKT1 mutations. Cancer Research. 73: 803-803. DOI: 10.1158/1538-7445.Am2013-803  0.727
2013 Ambady P, Holdhoff M, Ferrigno C, Grossman S, Anderson MD, Liu D, Conrad C, Penas-Prado M, Gilbert MR, Yung AWK, Groot Jd, Aoki T, Nishikawa R, Sugiyama K, Nonoguchi N, ... ... Louis D, et al. Neuro/Medical Oncology Neuro-Oncology. 15: 120-120. DOI: 10.1093/Neuonc/Not182  0.389
2012 Louis DN. The next step in brain tumor classification: "Let us now praise famous men"… or molecules? Acta Neuropathologica. 124: 761-2. PMID 23151844 DOI: 10.1007/S00401-012-1067-4  0.44
2012 Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed Whole Slide Image viewing system. Studies in Health Technology and Informatics. 179: 239-49. PMID 22925804 DOI: 10.3233/978-1-61499-086-4-239  0.37
2012 Chi AS, Batchelor TT, Dias-Santagata D, Borger D, Stiles CD, Wang DL, Curry WT, Wen PY, Ligon KL, Ellisen L, Louis DN, Iafrate AJ. Prospective, high-throughput molecular profiling of human gliomas. Journal of Neuro-Oncology. 110: 89-98. PMID 22821383 DOI: 10.1007/S11060-012-0938-9  0.396
2012 Panageas KS, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Cairncross JG, Roldán Urgoiti GB, Wen PY, Ligon KL, Schiff D, et al. Initial treatment patterns over time for anaplastic oligodendroglial tumors. Neuro-Oncology. 14: 761-7. PMID 22661585 DOI: 10.1093/Neuonc/Nos065  0.358
2012 Rheinbay E, Louis DN, Bernstein BE, Suvà ML. A tell-tail sign of chromatin: histone mutations drive pediatric glioblastoma. Cancer Cell. 21: 329-31. PMID 22439930 DOI: 10.1016/J.Ccr.2012.03.001  0.325
2012 Kanai R, Rabkin SD, Yip S, Sgubin D, Zaupa CM, Hirose Y, Louis DN, Wakimoto H, Martuza RL. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. Journal of the National Cancer Institute. 104: 42-55. PMID 22173583 DOI: 10.1093/Jnci/Djr509  0.468
2012 Yip S, Butterfield YS, Morozova O, Chittaranjan S, Blough MD, An J, Birol I, Chesnelong C, Chiu R, Chuah E, Corbett R, Docking R, Firme M, Hirst M, Jackman S, ... ... Louis DN, et al. Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. The Journal of Pathology. 226: 7-16. PMID 22072542 DOI: 10.1002/Path.2995  0.539
2012 Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-Oncology. 14: 132-44. PMID 22067563 DOI: 10.1093/Neuonc/Nor195  0.769
2012 Yagi Y, Yoshioka S, Kyusojin H, Onozato M, Mizutani Y, Osato K, Yada H, Mark EJ, Frosch MP, Louis DN. An ultra-high speed whole slide image viewing system. Analytical Cellular Pathology (Amsterdam). 35: 65-73. PMID 22063731 DOI: 10.3233/Acp-2011-0042  0.444
2012 Jansen M, Mohapatra G, Betensky RA, Keohane C, Louis DN. Gain of chromosome arm 1q in atypical meningioma correlates with shorter progression-free survival. Neuropathology and Applied Neurobiology. 38: 213-9. PMID 21988727 DOI: 10.1111/J.1365-2990.2011.01222.X  0.525
2012 Lassman AB, Iwamoto FM, Cloughesy TF, Aldape KD, Rivera AL, Eichler AF, Louis DN, Paleologos NA, Fisher BJ, Ashby LS, Gregory Cairncross J, Urgoiti GBR, Wen PY, Ligon KL, Schiff D, et al. Response to Weltman and Fleury Malheiros, re Lassman et al. Neuro-Oncology. 14: 677-678. DOI: 10.1093/Neuonc/Nos136  0.341
2011 Chi AS, Kwak EL, Clark JW, Wang DL, Louis DN, Iafrate AJ, Batchelor T. Clinical improvement and rapid radiographic regression induced by a MET inhibitor in a patient with MET-amplified glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2072. PMID 28019895 DOI: 10.1200/Jco.2011.29.15_Suppl.2072  0.358
2011 Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, Akhavanfard S, Cahill DP, Aldape KD, Betensky RA, Louis DN, Iafrate AJ. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell. 20: 810-7. PMID 22137795 DOI: 10.1016/J.Ccr.2011.11.005  0.686
2011 Dias-Santagata D, Lam Q, Vernovsky K, Vena N, Lennerz JK, Borger DR, Batchelor TT, Ligon KL, Iafrate AJ, Ligon AH, Louis DN, Santagata S. BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. Plos One. 6: e17948. PMID 21479234 DOI: 10.1371/Journal.Pone.0017948  0.424
2011 Camelo-Piragua S, Jansen M, Ganguly A, Kim JC, Cosper AK, Dias-Santagata D, Nutt CL, Iafrate AJ, Louis DN. A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53. Journal of Neuropathology and Experimental Neurology. 70: 110-5. PMID 21343879 DOI: 10.1097/Nen.0B013E31820565F9  0.718
2011 Horbinski C, Kofler J, Yeaney G, Camelo-Piragua S, Venneti S, Louis DN, Perry A, Murdoch G, Nikiforova M. Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas. Brain Pathology (Zurich, Switzerland). 21: 564-74. PMID 21314850 DOI: 10.1111/J.1750-3639.2011.00480.X  0.41
2011 Schindler G, Capper D, Meyer J, Janzarik W, Omran H, Herold-Mende C, Schmieder K, Wesseling P, Mawrin C, Hasselblatt M, Louis DN, Korshunov A, Pfister S, Hartmann C, Paulus W, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathologica. 121: 397-405. PMID 21274720 DOI: 10.1007/S00401-011-0802-6  0.577
2011 Mohapatra G, Engler DA, Starbuck KD, Kim JC, Bernay DC, Scangas GA, Rousseau A, Batchelor TT, Betensky RA, Louis DN. Genome-wide comparison of paired fresh frozen and formalin-fixed paraffin-embedded gliomas by custom BAC and oligonucleotide array comparative genomic hybridization: facilitating analysis of archival gliomas. Acta Neuropathologica. 121: 529-43. PMID 21080181 DOI: 10.1007/S00401-010-0773-Z  0.486
2011 Prithviraj GK, Sommers SR, Jump RL, Halmos B, Chambless LB, Parker SL, Hassam-Malani L, McGirt MJ, Thompson RC, Chambless LB, Parker SL, Hassam-Malani L, McGirt MJ, Thompson RC, Hunter K, ... ... Louis DN, ... ... Louis DN, et al. MEDICAL AND NEURO-ONCOLOGY Neuro-Oncology. 13: iii41-iii68. DOI: 10.1093/Neuonc/Nor152  0.603
2010 McDaniel S, Minnier J, Betensky RA, Mohapatra G, Shen Y, Gusella JF, Louis DN, Cai T. Assessing Population Level Genetic Instability via Moving Average. Statistics in Biosciences. 2: 120-136. PMID 22866169 DOI: 10.1007/S12561-010-9028-8  0.342
2010 Jansen M, Yip S, Louis DN. Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers. The Lancet. Neurology. 9: 717-26. PMID 20610347 DOI: 10.1016/S1474-4422(10)70105-8  0.605
2010 Dias-Santagata D, Akhavanfard S, David SS, Vernovsky K, Kuhlmann G, Boisvert SL, Stubbs H, McDermott U, Settleman J, Kwak EL, Clark JW, Isakoff SJ, Sequist LV, Engelman JA, Lynch TJ, ... ... Louis DN, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. Embo Molecular Medicine. 2: 146-58. PMID 20432502 DOI: 10.1002/Emmm.201000070  0.316
2010 van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K. Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 29: 3185-95. PMID 20305695 DOI: 10.1038/Onc.2010.75  0.534
2010 Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, ... ... Louis DN, et al. A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Research. 70: 2158-64. PMID 20215515 DOI: 10.1158/0008-5472.Can-09-3458  0.347
2010 Zhang X, Gejman R, Mahta A, Zhong Y, Rice KA, Zhou Y, Cheunsuchon P, Louis DN, Klibanski A. Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. Cancer Research. 70: 2350-8. PMID 20179190 DOI: 10.1158/0008-5472.Can-09-3885  0.791
2010 Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, Popoff S, Nutt CL, Louis DN, Cairncross JG, Gilbert MR, Phillips HS, Mehta MP, Chakravarti A, Pelloski CE, et al. A multigene predictor of outcome in glioblastoma. Neuro-Oncology. 12: 49-57. PMID 20150367 DOI: 10.1093/Neuonc/Nop007  0.652
2010 Camelo-Piragua S, Jansen M, Ganguly A, Kim JC, Louis DN, Nutt CL. Mutant IDH1-specific immunohistochemistry distinguishes diffuse astrocytoma from astrocytosis. Acta Neuropathologica. 119: 509-11. PMID 20044756 DOI: 10.1007/S00401-009-0632-Y  0.755
2010 Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Cohen EEW, Louis DN, Settleman J, Haber DA. Abstract 5757: A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers Cancer Research. 70: 5757-5757. DOI: 10.1158/1538-7445.Am10-5757  0.333
2010 Du J, Bernasconi P, He F, Julian B, Mani DR, Margolin A, Ross K, Clauser K, Finn SP, Beroukhim R, Burns M, Peng X, Hieronymus H, Maglathlin R, Lewis TA, ... ... Louis DN, et al. Abstract 5559: Proteomic identification of activated, essential tyrosine kinases in human cancers Cancer Research. 70: 5559-5559. DOI: 10.1158/1538-7445.Am10-5559  0.304
2009 Kaley TJ, Raizer JJ, Paleologos N, Kewalramani T, Grimm S, Louis DN, Cairncross JG, Abrey LE. Phase II trial of temozolomide (TMZ) followed by myeloablative chemotherapy with autologous peripheral blood progenitor cell rescue (APBPCR) for newly diagnosed anaplastic oligodendroglioma: An Oligodendroglioma Study Group trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2055. PMID 27964668 DOI: 10.1200/Jco.2009.27.15_Suppl.2055  0.307
2009 Quant EC, Silver M, Yip S, Ryg P, Provencher K, McCormack K, Louis DN, Betensky R, Nutt C, Batchelor TT. Case-control study of long-term survivors of glioblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e13021. PMID 27962816 DOI: 10.1200/Jco.2009.27.15_Suppl.E13021  0.665
2009 Gerstner ER, Yip S, Wang DL, Louis DN, Iafrate AJ, Batchelor TT. MGMT methylation status may predict survival in elderly patients with newly diagnosed glioblastoma (GBM). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e13023. PMID 27962794 DOI: 10.1200/Jco.2009.27.15_Suppl.E13023  0.462
2009 Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, et al. Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Archives of Pathology & Laboratory Medicine. 133: 1949-53. PMID 19961250 DOI: 10.1043/1543-2165-133.12.1949  0.461
2009 Gabeau-Lacet D, Engler D, Gupta S, Scangas GA, Betensky RA, Barker FG, Loeffler JS, Louis DN, Mohapatra G. Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome. Journal of Neuropathology and Experimental Neurology. 68: 1155-65. PMID 19918127 DOI: 10.1097/Nen.0B013E3181Ba3952  0.792
2009 Gerstner ER, Yip S, Wang DL, Louis DN, Iafrate AJ, Batchelor TT. Mgmt methylation is a prognostic biomarker in elderly patients with newly diagnosed glioblastoma. Neurology. 73: 1509-10. PMID 19884580 DOI: 10.1212/Wnl.0B013E3181Bf9907  0.476
2009 Snuderl M, Eichler AF, Ligon KL, Vu QU, Silver M, Betensky RA, Ligon AH, Wen PY, Louis DN, Iafrate AJ. Polysomy for chromosomes 1 and 19 predicts earlier recurrence in anaplastic oligodendrogliomas with concurrent 1p/19q loss. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6430-7. PMID 19808867 DOI: 10.1158/1078-0432.Ccr-09-0867  0.58
2009 Yip S, Miao J, Cahill DP, Iafrate AJ, Aldape K, Nutt CL, Louis DN. MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4622-9. PMID 19584161 DOI: 10.1158/1078-0432.Ccr-08-3012  0.745
2009 Aghi MK, Batchelor TT, Louis DN, Barker FG, Curry WT. Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q. Journal of Neuro-Oncology. 93: 115-20. PMID 19430887 DOI: 10.1007/S11060-009-9826-3  0.403
2009 DeSantis SM, Houseman EA, Coull BA, Louis DN, Mohapatra G, Betensky RA. A latent class model with hidden Markov dependence for array CGH data. Biometrics. 65: 1296-305. PMID 19397578 DOI: 10.1111/J.1541-0420.2009.01226.X  0.38
2009 Gabeau-Lacet D, Aghi M, Betensky RA, Barker FG, Loeffler JS, Louis DN. Bone involvement predicts poor outcome in atypical meningioma. Journal of Neurosurgery. 111: 464-71. PMID 19267533 DOI: 10.1016/J.Ijrobp.2008.06.1533  0.772
2009 Koga T, Morita A, Maruyama K, Tanaka M, Ino Y, Shibahara J, Louis DN, Reifenberger G, Itami J, Hara R, Saito N, Todo T. Long-term control of disseminated pleomorphic xanthoastrocytoma with anaplastic features by means of stereotactic irradiation. Neuro-Oncology. 11: 446-51. PMID 19164434 DOI: 10.1215/15228517-2008-112  0.54
2008 Cahill DP, Codd PJ, Batchelor TT, Curry WT, Louis DN. MSH6 inactivation and emergent temozolomide resistance in human glioblastomas. Clinical Neurosurgery. 55: 165-71. PMID 19248684  0.343
2008 Stegh AH, Chin L, Louis DN, DePinho RA. What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator. Cell Cycle (Georgetown, Tex.). 7: 2833-9. PMID 18769159 DOI: 10.4161/Cc.7.18.6759  0.311
2008 de la Iglesia N, Konopka G, Lim KL, Nutt CL, Bromberg JF, Frank DA, Mischel PS, Louis DN, Bonni A. Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5870-8. PMID 18524891 DOI: 10.1523/Jneurosci.5385-07.2008  0.658
2008 Mohile NA, Forsyth P, Stewart D, Raizer JJ, Paleologos N, Kewalramani T, Louis DN, Cairncross JG, Abrey LE. A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis. Journal of Neuro-Oncology. 89: 187-93. PMID 18458821 DOI: 10.1007/S11060-008-9603-8  0.327
2008 Lawlor MW, Nielsen GP, Louis DN. Malignant solitary fibrous tumour of the meninges with marked amianthoid fibre deposition. Neuropathology and Applied Neurobiology. 34: 569-72. PMID 18298634 DOI: 10.1111/J.1365-2990.2008.00943.X  0.503
2008 Yip S, Iafrate AJ, Louis DN. Molecular diagnostic testing in malignant gliomas: a practical update on predictive markers. Journal of Neuropathology and Experimental Neurology. 67: 1-15. PMID 18091559 DOI: 10.1097/Nen.0B013E31815F65Fb  0.505
2007 Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes & Development. 21: 2683-710. PMID 17974913 DOI: 10.1101/Gad.1596707  0.367
2007 Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathologica. 114: 97-109. PMID 17618441 DOI: 10.1007/S00401-007-0243-4  0.306
2007 Abrey LE, Louis DN, Paleologos N, Lassman AB, Raizer JJ, Mason W, Finlay J, MacDonald DR, DeAngelis LM, Cairncross JG. Survey of treatment recommendations for anaplastic oligodendroglioma. Neuro-Oncology. 9: 314-8. PMID 17435180 DOI: 10.1215/15228517-2007-002  0.32
2007 Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, Reavie LB, Batchelor TT, Futreal PA, Stratton MR, Curry WT, Iafrate AJ, Louis DN. Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2038-45. PMID 17404084 DOI: 10.1158/1078-0432.Ccr-06-2149  0.579
2007 Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, ... ... Louis DN, et al. Patterns of somatic mutation in human cancer genomes. Nature. 446: 153-8. PMID 17344846 DOI: 10.1038/Nature05610  0.478
2007 Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron. 53: 503-17. PMID 17296553 DOI: 10.1016/J.Neuron.2007.01.009  0.324
2007 Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell. 11: 83-95. PMID 17222792 DOI: 10.1016/J.Ccr.2006.11.021  0.539
2007 Stegh AH, Kim H, Bachoo RM, Forloney KL, Zhang J, Schulze H, Park K, Hannon GJ, Yuan J, Louis DN, DePinho RA, Chin L. Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes & Development. 21: 98-111. PMID 17210792 DOI: 10.1101/Gad.1480007  0.316
2007 Mueller W, Nutt CL, Ehrich M, Riemenschneider MJ, von Deimling A, van den Boom D, Louis DN. Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. Oncogene. 26: 583-93. PMID 16909125 DOI: 10.1038/Sj.Onc.1209805  0.739
2007 Batchelor T, Sorensen AG, Ancukiewicz M, Duda DG, Louis DN, Plotkin SR, Ivy P, Wen PY, Loeffler JS, Jain R. A phase II trial of AZD2171 (cediranib), an oral pan-VEGF receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma Journal of Clinical Oncology. 25: 2001-2001. DOI: 10.1200/Jco.2007.25.18_Suppl.2001  0.321
2006 Louis DN. Molecular pathology of malignant gliomas. Annual Review of Pathology. 1: 97-117. PMID 18039109 DOI: 10.1146/Annurev.Pathol.1.110304.100043  0.433
2006 Mizoguchi M, Betensky RA, Batchelor TT, Bernay DC, Louis DN, Nutt CL. Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival. Journal of Neuropathology and Experimental Neurology. 65: 1181-8. PMID 17146292 DOI: 10.1097/01.Jnen.0000248549.14962.B2  0.724
2006 Rousseau A, Nutt CL, Betensky RA, Iafrate AJ, Han M, Ligon KL, Rowitch DH, Louis DN. Expression of oligodendroglial and astrocytic lineage markers in diffuse gliomas: use of YKL-40, ApoE, ASCL1, and NKX2-2. Journal of Neuropathology and Experimental Neurology. 65: 1149-56. PMID 17146289 DOI: 10.1097/01.Jnen.0000248543.90304.2B  0.724
2006 Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, Richardson A, Khatry D, Feng B, Sinha R, Louis DN, Quackenbush J, Black PM, Chin L, DePinho RA. Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Research. 66: 11502-13. PMID 17114236 DOI: 10.1158/0008-5472.Can-06-2072  0.347
2006 Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 12873-8. PMID 16908838 DOI: 10.1073/Pnas.0605496103  0.306
2006 Sequist LV, Joshi VA, Jänne PA, Bell DW, Fidias P, Lindeman NI, Louis DN, Lee JC, Mark EJ, Longtine J, Verlander P, Kucherlapati R, Meyerson M, Haber DA, Johnson BE, et al. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4403s-4408s. PMID 16857818 DOI: 10.1158/1078-0432.Ccr-06-0099  0.309
2006 Riemenschneider MJ, Betensky RA, Pasedag SM, Louis DN. AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling. Cancer Research. 66: 5618-23. PMID 16740698 DOI: 10.1158/0008-5472.Can-06-0364  0.316
2006 Mohapatra G, Betensky RA, Miller ER, Carey B, Gaumont LD, Engler DA, Louis DN. Glioma test array for use with formalin-fixed, paraffin-embedded tissue: array comparative genomic hybridization correlates with loss of heterozygosity and fluorescence in situ hybridization. The Journal of Molecular Diagnostics : Jmd. 8: 268-76. PMID 16645215 DOI: 10.2353/Jmoldx.2006.050109  0.399
2006 Hunter C, Smith R, Cahill DP, Stephens P, Stevens C, Teague J, Greenman C, Edkins S, Bignell G, Davies H, O'Meara S, Parker A, Avis T, Barthorpe S, Brackenbury L, ... ... Louis DN, et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. Cancer Research. 66: 3987-91. PMID 16618716 DOI: 10.1158/0008-5472.Can-06-0127  0.639
2006 Engler DA, Mohapatra G, Louis DN, Betensky RA. A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations. Biostatistics (Oxford, England). 7: 399-421. PMID 16401686 DOI: 10.1093/Biostatistics/Kxj015  0.323
2005 Aghi M, Gaviani P, Henson JW, Batchelor TT, Louis DN, Barker FG. Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8600-5. PMID 16361543 DOI: 10.1158/1078-0432.Ccr-05-0713  0.311
2005 Dong S, Nutt CL, Betensky RA, Stemmer-Rachamimov AO, Denko NC, Ligon KL, Rowitch DH, Louis DN. Histology-based expression profiling yields novel prognostic markers in human glioblastoma. Journal of Neuropathology and Experimental Neurology. 64: 948-55. PMID 16254489 DOI: 10.1097/01.Jnen.0000186940.14779.90  0.784
2005 Riemenschneider MJ, Mueller W, Betensky RA, Mohapatra G, Louis DN. In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation. The American Journal of Pathology. 167: 1379-87. PMID 16251422 DOI: 10.1016/S0002-9440(10)61225-4  0.528
2005 Henson JW, Hobbs W, Chakravarti A, Louis DN. Alterations in p53, p21, and MIB-1 labeling index in primary human astrocytomas following radiation therapy. Journal of Neuro-Oncology. 74: 151-4. PMID 16193385 DOI: 10.1007/S11060-004-6911-5  0.401
2005 McDonald JM, See SJ, Tremont IW, Colman H, Gilbert MR, Groves M, Burger PC, Louis DN, Giannini C, Fuller G, Passe S, Blair H, Jenkins RB, Yang H, Ledoux A, et al. The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors. Cancer. 104: 1468-77. PMID 16088966 DOI: 10.1002/Cncr.21338  0.324
2005 Ma D, Nutt CL, Shanehsaz P, Peng X, Louis DN, Kaetzel DM. Autocrine platelet-derived growth factor-dependent gene expression in glioblastoma cells is mediated largely by activation of the transcription factor sterol regulatory element binding protein and is associated with altered genotype and patient survival in human brain tumors. Cancer Research. 65: 5523-34. PMID 15994924 DOI: 10.1158/0008-5472.Can-04-2582  0.669
2005 Shih HA, Betensky RA, Dorfman MV, Louis DN, Loeffler JS, Batchelor TT. Genetic analyses for predictors of radiation response in glioblastoma. International Journal of Radiation Oncology, Biology, Physics. 63: 704-10. PMID 15978739 DOI: 10.1016/J.Ijrobp.2005.03.059  0.406
2005 Dahiya S, Sarkar C, Hedley-Whyte ET, Sharma MC, Zervas NT, Sridhar E, Louis DN. Spindle cell oncocytoma of the adenohypophysis: report of two cases. Acta Neuropathologica. 110: 97-9. PMID 15973544 DOI: 10.1007/S00401-005-1009-5  0.699
2005 Mueller W, Mizoguchi M, Silen E, D'Amore K, Nutt CL, Louis DN. Mutations of the PIK3CA gene are rare in human glioblastoma. Acta Neuropathologica. 109: 654-5. PMID 15924252 DOI: 10.1007/S00401-005-1001-0  0.768
2005 Betensky RA, Nutt CL, Batchelor TT, Louis DN. Statistical considerations for immunohistochemistry panel development after gene expression profiling of human cancers. The Journal of Molecular Diagnostics : Jmd. 7: 276-82. PMID 15858152 DOI: 10.1016/S1525-1578(10)60555-7  0.653
2005 Nutt CL, Betensky RA, Brower MA, Batchelor TT, Louis DN, Stemmer-Rachamimov AO. YKL-40 is a differential diagnostic marker for histologic subtypes of high-grade gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2258-64. PMID 15788675 DOI: 10.1158/1078-0432.Ccr-04-1601  0.8
2005 Kreiger PA, Okada Y, Simon S, Rorke LB, Louis DN, Golden JA. Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas. Acta Neuropathologica. 109: 387-92. PMID 15739101 DOI: 10.1007/S00401-004-0976-2  0.8
2005 Voloschin AD, Louis DN, Cosgrove GR, Batchelor TT. Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study. Neuro-Oncology. 7: 97-100. PMID 15701287 DOI: 10.1215/S1152851704000560  0.436
2004 Mizoguchi M, Nutt CL, Mohapatra G, Louis DN. Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas. Brain Pathology (Zurich, Switzerland). 14: 372-7. PMID 15605984 DOI: 10.1111/J.1750-3639.2004.Tb00080.X  0.718
2004 Plummer NW, Gallione CJ, Srinivasan S, Zawistowski JS, Louis DN, Marchuk DA. Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. The American Journal of Pathology. 165: 1509-18. PMID 15509522 DOI: 10.1016/S0002-9440(10)63409-8  0.352
2004 Chiocca EA, Abbed KM, Tatter S, Louis DN, Hochberg FH, Barker F, Kracher J, Grossman SA, Fisher JD, Carson K, Rosenblum M, Mikkelsen T, Olson J, Markert J, Rosenfeld S, et al. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 958-66. PMID 15509513 DOI: 10.1016/J.Ymthe.2004.07.021  0.621
2004 Sloan KE, Eustace BK, Stewart JK, Zehetmeier C, Torella C, Simeone M, Roy JE, Unger C, Louis DN, Ilag LL, Jay DG. CD155/PVR plays a key role in cell motility during tumor cell invasion and migration. Bmc Cancer. 4: 73. PMID 15471548 DOI: 10.1186/1471-2407-4-73  0.3
2004 Mrak RE, Yasargil MG, Mohapatra G, Earel J, Louis DN. Atypical extraventricular neurocytoma with oligodendroglioma-like spread and an unusual pattern of chromosome 1p and 19q loss. Human Pathology. 35: 1156-9. PMID 15343519 DOI: 10.1016/J.Humpath.2004.05.005  0.42
2004 Megyesi JF, Kachur E, Lee DH, Zlatescu MC, Betensky RA, Forsyth PA, Okada Y, Sasaki H, Mizoguchi M, Louis DN, Cairncross JG. Imaging correlates of molecular signatures in oligodendrogliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4303-6. PMID 15240515 DOI: 10.1158/1078-0432.Ccr-04-0209  0.782
2004 Chang SM, Seiferheld W, Curran W, Share R, Atkins J, Choucair A, Kresl J, Thoron L, Cairncross G, Gilbert M, Bahary JP, Dolinskas C, Louis DN, Bushunow P, Buckner J, et al. Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors. International Journal of Radiation Oncology, Biology, Physics. 59: 1122-6. PMID 15234047 DOI: 10.1016/J.Ijrobp.2004.01.002  0.304
2004 Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. Journal of Neuropathology and Experimental Neurology. 63: 499-509. PMID 15198128 DOI: 10.1093/Jnen/63.5.499  0.685
2004 Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.Can-03-4079  0.687
2004 Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine. 350: 2129-39. PMID 15118073 DOI: 10.1056/Nejmoa040938  0.321
2004 Kiehl TR, Kalkanis SN, Louis DN. Pigmented central neurocytoma. Acta Neuropathologica. 107: 571-4. PMID 14991386 DOI: 10.1007/S00401-004-0835-1  0.757
2004 Yang C, Ionescu-Tiba V, Burns K, Gadd M, Zukerberg L, Louis DN, Sgroi D, Schmidt EV. The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer. The American Journal of Pathology. 164: 1031-8. PMID 14982856 DOI: 10.1016/S0002-9440(10)63190-2  0.317
2004 Batchelor TT, Betensky RA, Esposito JM, Pham LD, Dorfman MV, Piscatelli N, Jhung S, Rhee D, Louis DN. Age-dependent prognostic effects of genetic alterations in glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 228-33. PMID 14734474 DOI: 10.1158/1078-0432.Ccr-0841-3  0.366
2004 Mizoguchi M, Nutt CL, Louis DN. Mutation analysis of CBL-C and SPRED3 on 19q in human glioblastoma. Neurogenetics. 5: 81-2. PMID 14618415 DOI: 10.1007/S10048-003-0164-X  0.712
2003 Gutmann DH, James CD, Poyhonen M, Louis DN, Ferner R, Guha A, Hariharan S, Viskochil D, Perry A. Molecular analysis of astrocytomas presenting after age 10 in individuals with NF1. Neurology. 61: 1397-400. PMID 14638962 DOI: 10.1212/Wnl.61.10.1397  0.367
2003 Betensky RA, Louis DN, Cairncross JG. Analysis of a molecular genetic neuro-oncology study with partially biased selection. Biostatistics (Oxford, England). 4: 167-78. PMID 12925514 DOI: 10.1093/Biostatistics/4.2.167  0.367
2003 MacCollin M, Willett C, Heinrich B, Jacoby LB, Acierno JS, Perry A, Louis DN. Familial schwannomatosis: exclusion of the NF2 locus as the germline event. Neurology. 60: 1968-74. PMID 12821741 DOI: 10.1212/01.Wnl.0000070184.08740.E0  0.397
2003 Hampl JA, Camp SM, Mydlarz WK, Hampl M, Ichikawa T, Chiocca EA, Louis DN, Sena-Esteves M, Breakefield XO. Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors. Human Gene Therapy. 14: 611-26. PMID 12804144 DOI: 10.1089/104303403321618137  0.377
2003 Nutt CL, Mani DR, Betensky RA, Tamayo P, Cairncross JG, Ladd C, Pohl U, Hartmann C, McLaughlin ME, Batchelor TT, Black PM, von Deimling A, Pomeroy SL, Golub TR, Louis DN. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Research. 63: 1602-7. PMID 12670911  0.748
2003 Braaten KM, Betensky RA, de Leval L, Okada Y, Hochberg FH, Louis DN, Harris NL, Batchelor TT. BCL-6 expression predicts improved survival in patients with primary central nervous system lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1063-9. PMID 12631608  0.701
2003 Reifenberger G, Louis DN. Oligodendroglioma: toward molecular definitions in diagnostic neuro-oncology. Journal of Neuropathology and Experimental Neurology. 62: 111-26. PMID 12578221 DOI: 10.1093/Jnen/62.2.111  0.475
2003 Okada Y, Hurwitz EE, Esposito JM, Brower MA, Nutt CL, Louis DN. Selection pressures of TP53 mutation and microenvironmental location influence epidermal growth factor receptor gene amplification in human glioblastomas. Cancer Research. 63: 413-6. PMID 12543796  0.773
2003 Heinrich B, Hartmann C, Stemmer-Rachamimov AO, Louis DN, MacCollin M. Multiple meningiomas: Investigating the molecular basis of sporadic and familial forms. International Journal of Cancer. Journal International Du Cancer. 103: 483-8. PMID 12478663 DOI: 10.1002/Ijc.10840  0.769
2002 Lam P, Hui KM, Wang Y, Allen PD, Louis DN, Yuan CJ, Breakefield XO. Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors. Human Gene Therapy. 13: 2147-59. PMID 12542846 DOI: 10.1089/104303402320987842  0.339
2002 Rabinov JD, Lee PL, Barker FG, Louis DN, Harsh GR, Cosgrove GR, Chiocca EA, Thornton AF, Loeffler JS, Henson JW, Gonzalez RG. In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience. Radiology. 225: 871-9. PMID 12461273 DOI: 10.1148/Radiol.2253010997  0.36
2002 Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, et al. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 21: 7453-63. PMID 12386807 DOI: 10.1038/Sj.Onc.1205936  0.414
2002 Hartmann C, Johnk L, Kitange G, Wu Y, Ashworth LK, Jenkins RB, Louis DN. Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19. Cancer Research. 62: 4100-8. PMID 12124348  0.487
2002 Mueller W, Hartmann C, Hoffmann A, Lanksch W, Kiwit J, Tonn J, Veelken J, Schramm J, Weller M, Wiestler OD, Louis DN, von Deimling A. Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets. The American Journal of Pathology. 161: 313-9. PMID 12107116 DOI: 10.1016/S0002-9440(10)64183-1  0.68
2002 Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T. Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell. 1: 157-68. PMID 12086874 DOI: 10.1016/S1535-6108(02)00029-6  0.332
2002 Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 1: 269-77. PMID 12086863 DOI: 10.1016/S1535-6108(02)00046-6  0.372
2002 Okada Y, Nishikawa R, Matsutani M, Louis DN. Hypomethylated X chromosome gain and rare isochromosome 12p in diverse intracranial germ cell tumors. Journal of Neuropathology and Experimental Neurology. 61: 531-8. PMID 12071636 DOI: 10.1093/Jnen/61.6.531  0.741
2002 Hartmann C, Johnk L, Sasaki H, Jenkins RB, Louis DN. Novel PLA2G4C polymorphism as a molecular diagnostic assay for 19q loss in human gliomas. Brain Pathology (Zurich, Switzerland). 12: 178-82. PMID 11958371 DOI: 10.1111/J.1750-3639.2002.Tb00432.X  0.698
2002 Schmidt MC, Antweiler S, Urban N, Mueller W, Kuklik A, Meyer-Puttlitz B, Wiestler OD, Louis DN, Fimmers R, von Deimling A. Impact of genotype and morphology on the prognosis of glioblastoma. Journal of Neuropathology and Experimental Neurology. 61: 321-8. PMID 11939587 DOI: 10.1093/Jnen/61.4.321  0.596
2002 Sasaki H, Betensky RA, Cairncross JG, Louis DN. DMBT1 polymorphisms: relationship to malignant glioma tumorigenesis. Cancer Research. 62: 1790-6. PMID 11912156  0.604
2002 Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK. The WHO classification of tumors of the nervous system. Journal of Neuropathology and Experimental Neurology. 61: 215-25; discussion 2. PMID 11895036 DOI: 10.1093/Jnen/61.3.215  0.433
2002 Sasaki H, Zlatescu MC, Betensky RA, Johnk LB, Cutone AN, Cairncross JG, Louis DN. Histopathological-molecular genetic correlations in referral pathologist-diagnosed low-grade "oligodendroglioma". Journal of Neuropathology and Experimental Neurology. 61: 58-63. PMID 11829344 DOI: 10.1093/Jnen/61.1.58  0.664
2002 Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, ... ... Louis DN, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 415: 436-42. PMID 11807556 DOI: 10.1038/415436A  0.345
2002 Smith ER, Ott M, Wain J, Louis DN, Chiocca EA. Massive growth of a meningioma into the brachial plexus and thoracic cavity after intraspinal and supraclavicular resection. Case report and review of the literature. Journal of Neurosurgery. 96: 107-11. PMID 11795697 DOI: 10.3171/Spi.2002.96.1.0107  0.314
2001 Wong AJ, Padarathsingh M, Louis DN, Rempel S, Ladisch S, Gladson C. New approaches to the molecular biology, classification, and therapy of nervous system tumors: a workshop of the National Institutes of Health Pathology B study section. The American Journal of Pathology. 159: 1971-4. PMID 11696458 DOI: 10.1016/S0002-9440(10)63044-1  0.419
2001 Primavera J, Nikas DC, Zamani AA, Shafman T, Alexander E, De Girolami U, Louis DN. Clear cell pleomorphic xanthoastrocytoma: case report. Acta Neuropathologica. 102: 404-8. PMID 11603818 DOI: 10.1007/S004010100380  0.672
2001 Zlatescu MC, TehraniYazdi A, Sasaki H, Megyesi JF, Betensky RA, Louis DN, Cairncross JG. Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms. Cancer Research. 61: 6713-5. PMID 11559541  0.327
2001 Louis DN, Holland EC, Cairncross JG. Glioma classification: a molecular reappraisal. The American Journal of Pathology. 159: 779-86. PMID 11549567 DOI: 10.1016/S0002-9440(10)61750-6  0.42
2001 Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM. Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 10851-6. PMID 11526205 DOI: 10.1073/Pnas.181340798  0.4
2001 Lu X, Magrane G, Yin C, Louis DN, Gray J, Van Dyke T. Selective inactivation of p53 facilitates mouse epithelial tumor progression without chromosomal instability. Molecular and Cellular Biology. 21: 6017-30. PMID 11486039 DOI: 10.1128/Mcb.21.17.6017-6030.2001  0.434
2001 Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes & Development. 15: 1913-25. PMID 11485986 DOI: 10.1101/Gad.903001  0.698
2001 Blakley P, Louis DN, Short MP, MacCollin M. A clinical study of patients with multiple isolated neurofibromas. Journal of Medical Genetics. 38: 485-8. PMID 11476067 DOI: 10.1136/Jmg.38.7.485  0.603
2001 Niida Y, Stemmer-Rachamimov AO, Logrip M, Tapon D, Perez R, Kwiatkowski DJ, Sims K, MacCollin M, Louis DN, Ramesh V. Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions. American Journal of Human Genetics. 69: 493-503. PMID 11468687 DOI: 10.1086/321972  0.707
2001 Sasaki H, Zlatescu MC, Betensky RA, Ino Y, Cairncross JG, Louis DN. PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosis. The American Journal of Pathology. 159: 359-67. PMID 11438483 DOI: 10.1016/S0002-9440(10)61702-6  0.733
2001 Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA. Malignant glioma: genetics and biology of a grave matter. Genes & Development. 15: 1311-33. PMID 11390353 DOI: 10.1101/Gad.891601  0.407
2001 Ino Y, Betensky RA, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Ramsay DA, Cairncross JG, Louis DN. Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 839-45. PMID 11309331  0.759
2001 Murthy V, Stemmer-Rachamimov AO, Haddad LA, Roy JE, Cutone AN, Beauchamp RL, Smith N, Louis DN, Ramesh V. Developmental expression of the tuberous sclerosis proteins tuberin and hamartin. Acta Neuropathologica. 101: 202-10. PMID 11307618 DOI: 10.1007/S004010000269  0.65
2001 Campen R, Mankin H, Louis DN, Hirano M, Maccollin M. Familial occurrence of adiposis dolorosa. Journal of the American Academy of Dermatology. 44: 132-6. PMID 11148491 DOI: 10.1067/Mjd.2001.110872  0.367
2001 Stemmer-Rachamimov AO, Wiederhold T, Nielsen GP, James M, Pinney-Michalowski D, Roy JE, Cohen WA, Ramesh V, Louis DN. NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas. The American Journal of Pathology. 158: 57-62. PMID 11141479 DOI: 10.1016/S0002-9440(10)63944-2  0.632
2000 Park CC, Hartmann C, Folkerth R, Loeffler JS, Wen PY, Fine HA, Black PM, Shafman T, Louis DN. Systemic metastasis in glioblastoma may represent the emergence of neoplastic subclones. Journal of Neuropathology and Experimental Neurology. 59: 1044-50. PMID 11138924 DOI: 10.1093/Jnen/59.12.1044  0.601
2000 Tortosa A, Ino Y, Odell N, Swilley S, Sasaki H, Louis DN, Henson JW. Molecular genetics of radiographically defined de novo glioblastoma multiforme. Neuropathology and Applied Neurobiology. 26: 544-52. PMID 11123721 DOI: 10.1046/J.0305-1846.2000.00290.X  0.703
2000 Ino Y, Wahrer DC, Bell DW, Haber DA, Louis DN. Mutation analysis of the hCHK2 gene in primary human malignant gliomas. Neurogenetics. 3: 45-6. PMID 11085597 DOI: 10.1007/PL00022979  0.486
2000 Bauman GS, Ino Y, Ueki K, Zlatescu MC, Fisher BJ, Macdonald DR, Stitt L, Louis DN, Cairncross JG. Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas. International Journal of Radiation Oncology, Biology, Physics. 48: 825-30. PMID 11020580 DOI: 10.1016/S0360-3016(00)00703-3  0.66
2000 Chan AW, Tarbell NJ, Black PM, Louis DN, Frosch MP, Ancukiewicz M, Chapman P, Loeffler JS. Adult medulloblastoma: prognostic factors and patterns of relapse. Neurosurgery. 47: 623-31; discussion 6. PMID 10981749 DOI: 10.1097/00006123-200009000-00018  0.508
2000 Misdraji J, Ino Y, Louis DN, Rosenberg AE, Chiocca EA, Harris NL. Primary lymphoma of peripheral nerve: report of four cases. The American Journal of Surgical Pathology. 24: 1257-65. PMID 10976700 DOI: 10.1097/00000478-200009000-00009  0.545
2000 Smith JS, Tachibana I, Lee HK, Qian J, Pohl U, Mohrenweiser HW, Borell TJ, Hosek SM, Soderberg CL, von Deimling A, Perry A, Scheithauer BW, Louis DN, Jenkins RB. Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers. Genes, Chromosomes & Cancer. 29: 16-25. PMID 10918389 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1007>3.3.Co;2-9  0.571
2000 Smith JS, Tachibana I, Lee HK, Qian J, Pohl U, Mohrenweiser HW, Borell TJ, Hosek SM, Soderberg CL, Deimling Av, Perry A, Scheithauer BW, Louis DN, Jenkins RB. Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers: Mapping of the Glioma 19q Tumor Suppressor Gene Genes, Chromosomes and Cancer. 29: 16-25. PMID 10918389 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1007>3.0.Co;2-I  0.582
2000 Ino Y, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Jhung S, Ramsay DA, von Deimling A, Louis DN, Cairncross JG. Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss. Journal of Neurosurgery. 92: 983-90. PMID 10839259 DOI: 10.3171/Jns.2000.92.6.0983  0.813
2000 Møller MB, Kania PW, Ino Y, Gerdes AM, Nielsen O, Louis DN, Skjødt K, Pedersen NT. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A. Leukemia. 14: 898-904. PMID 10803523 DOI: 10.1038/Sj.Leu.2401761  0.538
2000 Harsh GR, Deisboeck TS, Louis DN, Hilton J, Colvin M, Silver JS, Qureshi NH, Kracher J, Finkelstein D, Chiocca EA, Hochberg FH. Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study. Journal of Neurosurgery. 92: 804-11. PMID 10794295 DOI: 10.3171/Jns.2000.92.5.0804  0.441
2000 Ikeda K, Wakimoto H, Ichikawa T, Jhung S, Hochberg FH, Louis DN, Chiocca EA. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant. Journal of Virology. 74: 4765-75. PMID 10775615 DOI: 10.1128/Jvi.74.10.4765-4775.2000  0.351
2000 Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB. A transcript map of the chromosome 19q-arm glioma tumor suppressor region. Genomics. 64: 44-50. PMID 10708517 DOI: 10.1006/Geno.1999.6101  0.663
2000 Pohl U, Smith JS, Tachibana I, Ueki K, Lee HK, Ramaswamy S, Wu Q, Mohrenweiser HW, Jenkins RB, Louis DN. EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins. Genomics. 63: 255-62. PMID 10673336 DOI: 10.1006/Geno.1999.6087  0.664
2000 Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Molecular and Cellular Biology. 20: 1436-47. PMID 10648628 DOI: 10.1128/Mcb.20.4.1436-1447.2000  0.498
1999 Nielsen GP, Stemmer-Rachamimov AO, Ino Y, Moller MB, Rosenberg AE, Louis DN. Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. The American Journal of Pathology. 155: 1879-84. PMID 10595918 DOI: 10.1016/S0002-9440(10)65507-1  0.741
1999 Sahoo T, Johnson EW, Thomas JW, Kuehl PM, Jones TL, Dokken CG, Touchman JW, Gallione CJ, Lee-Lin SQ, Kosofsky B, Kurth JH, Louis DN, Mettler G, Morrison L, Gil-Nagel A, et al. Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1). Human Molecular Genetics. 8: 2325-33. PMID 10545614 DOI: 10.1093/Hmg/8.12.2325  0.355
1999 Peters N, Smith JS, Tachibana I, Lee HK, Pohl U, Portier BP, Louis DN, Jenkins RB. The human glia maturation factor-gamma gene: genomic structure and mutation analysis in gliomas with chromosome 19q loss. Neurogenetics. 2: 163-6. PMID 10541589 DOI: 10.1007/S100480050077  0.673
1999 Pohl U, Cairncross JG, Louis DN. Homozygous deletions of the CDKN2C/p18INK4C gene on the short arm of chromosome 1 in anaplastic oligodendrogliomas. Brain Pathology (Zurich, Switzerland). 9: 639-43. PMID 10517502  0.56
1999 Castells A, Ino Y, Louis DN, Ramesh V, Gusella JF, Rustgi AK. Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer. Gastroenterology. 117: 831-7. PMID 10500065 DOI: 10.1016/S0016-5085(99)70341-0  0.574
1999 Nielsen GP, Stemmer-Rachamimov AO, Shaw J, Roy JE, Koh J, Louis DN. Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 1137-43. PMID 10496532  0.654
1999 Ino Y, Silver JS, Blazejewski L, Nishikawa R, Matsutani M, von Deimling A, Louis DN. Common regions of deletion on chromosome 22q12.3-q13.1 and 22q13.2 in human astrocytomas appear related to malignancy grade. Journal of Neuropathology and Experimental Neurology. 58: 881-5. PMID 10446812 DOI: 10.1097/00005072-199908000-00010  0.554
1999 Ikeda K, Ichikawa T, Wakimoto H, Silver JS, Deisboeck TS, Finkelstein D, Harsh GR, Louis DN, Bartus RT, Hochberg FH, Chiocca EA. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nature Medicine. 5: 881-7. PMID 10426310 DOI: 10.1038/11320  0.358
1999 Taylor MD, Perry J, Zlatescu MC, Stemmer-Rachamimov AO, Ang LC, Ino Y, Schwartz M, Becker LE, Louis DN, Cairncross JG. The hPMS2 exon 5 mutation and malignant glioma. Case report. Journal of Neurosurgery. 90: 946-50. PMID 10223463 DOI: 10.3171/jns.1999.90.5.0946  0.766
1999 Perry JR, Louis DN, Cairncross JG. Current treatment of oligodendrogliomas. Archives of Neurology. 56: 434-6. PMID 10199331 DOI: 10.1001/Archneur.56.4.434  0.356
1999 Møller MB, Ino Y, Gerdes AM, Skjødt K, Louis DN, Pedersen NT. Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma. Leukemia. 13: 453-9. PMID 10086736  0.458
1999 Rabinov J, Lee PL, Cheng LL, Barker FG, Louis DN, Gonzalez RG. MR Spectroscopy at 3 Tesla Differentiates Tumor Recurrence from Radiation Change in Patients with Astrocytomas Neurosurgery. 45: 728-728. DOI: 10.1097/00006123-199909000-00181  0.345
1999 Louis DN, Zlatescu MC, Ino Y, Gregory J. LONG SURVIVALS AND THERAPEUTIC RESPONSES IN HIGH-GRADE GLIOMAS WITH CHROMOSOME 1p LOSS THAT ARE NOT CLASSIC ANAPLASTIC OLIGODENDROGLIOMAS Journal of Neuropathology and Experimental Neurology. 58: 512. DOI: 10.1097/00005072-199905000-00025  0.531
1999 DE GIROLAMI UL, LOUIS DN, SCHOENE WC, VONSATTEL JG, HEDLEY-WHYTE ET. Edward Peirson Richardson, Jr. 1918–1998 Journal of Neuropathology and Experimental Neurology. 58: 506-508. DOI: 10.1097/00005072-199905000-00011  0.601
1999 Vonsattel JPG, Louis DN, De Girolami U. Hommage to Edward Peirson Richardson, Jr. | Hommage a Edward Peirson Richardson, Jr. 1918-1998 Revue Neurologique. 155: 1088-1089.  0.526
1998 Stemmer-Rachamimov AO, Nielsen GP, Rosenberg AE, Louis DN, Jones D, Ramesh V, Gusella JF, Jacoby LB. The NF2 gene and merlin protein in human osteosarcomas. Neurogenetics. 2: 73-4. PMID 9933303 DOI: 10.1007/S100480050054  0.647
1998 Stemmer-Rachamimov AO, Ino Y, Lim ZY, Jacoby LB, MacCollin M, Gusella JF, Ramesh V, Louis DN. Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2. Journal of Neuropathology and Experimental Neurology. 57: 1164-7. PMID 9862639 DOI: 10.1097/00005072-199812000-00008  0.74
1998 Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR, Silver JS, Stark PC, Macdonald DR, Ino Y, Ramsay DA, Louis DN. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. Journal of the National Cancer Institute. 90: 1473-9. PMID 9776413 DOI: 10.1093/Jnci/90.19.1473  0.672
1998 Herrlinger U, Kramm CM, Aboody-Guterman KS, Silver JS, Ikeda K, Johnston KM, Pechan PA, Barth RF, Finkelstein D, Chiocca EA, Louis DN, Breakefield XO. Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector. Gene Therapy. 5: 809-19. PMID 9747461 DOI: 10.1038/Sj.Gt.3300643  0.327
1998 Nielsen GP, Burns KL, Rosenberg AE, Louis DN. CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations. The American Journal of Pathology. 153: 159-63. PMID 9665476 DOI: 10.1016/S0002-9440(10)65556-3  0.445
1998 Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG, Iliopoulos O. The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Molecular Cell. 1: 959-68. PMID 9651579 DOI: 10.1016/S1097-2765(00)80096-9  0.653
1998 Duerr EM, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, Louis DN, Schramm J, Wiestler OD, Parsons R, Eng C, von Deimling A. PTEN mutations in gliomas and glioneuronal tumors. Oncogene. 16: 2259-64. PMID 9619835 DOI: 10.1038/Sj.Onc.1201756  0.616
1998 Burns KL, Ueki K, Jhung SL, Koh J, Louis DN. Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas. Journal of Neuropathology and Experimental Neurology. 57: 122-30. PMID 9600204 DOI: 10.1097/00005072-199802000-00003  0.572
1998 Cobbers JM, Wolter M, Reifenberger J, Ring GU, Jessen F, An HX, Niederacher D, Schmidt EE, Ichimura K, Floeth F, Kirsch L, Borchard F, Louis DN, Collins VP, Reifenberger G. Frequent inactivation of CDKN2A and rare mutation of TP53 in PCNSL. Brain Pathology (Zurich, Switzerland). 8: 263-76. PMID 9546285 DOI: 10.1111/J.1750-3639.1998.Tb00152.X  0.462
1998 Husain N, Chiocca EA, Rainov N, Louis DN, Zervas NT. Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines. Acta Neuropathologica. 95: 287-90. PMID 9542594 DOI: 10.1007/S004010050799  0.392
1998 Stemmer-Rachamimov AO, Nielsen GP, Louis DN. EXPRESSION OF THE p16 PROTEIN IN THE HUMAN NERVOUS SYSTEM AND OTHER TISSUES Journal of Neuropathology and Experimental Neurology. 57: 499. DOI: 10.1097/00005072-199805000-00138  0.645
1998 Louis DN, Cairncross JG. SPECIFIC CHROMOSOMAL LOSSES PREDICT CHEMOTHERAPEUTIC RESPONSE AND SURVIVAL IN PATIENTS WITH ANAPLASTIC OLIGODENDROGLIOMAS Journal of Neuropathology and Experimental Neurology. 57: 472. DOI: 10.1097/00005072-199805000-00027  0.303
1997 Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN. ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3. Neurogenetics. 1: 31-6. PMID 10735272 DOI: 10.1007/S100480050005  0.548
1997 Chung DC, Smith AP, Louis DN, Graeme-Cook F, Warshaw AL, Arnold A. Analysis of the retinoblastoma tumour suppressor gene in pancreatic endocrine tumours. Clinical Endocrinology. 47: 523-8. PMID 9425391 DOI: 10.1046/J.1365-2265.1997.2861110.X  0.361
1997 Stemmer-Rachamimov AO, Xu L, Gonzalez-Agosti C, Burwick JA, Pinney D, Beauchamp R, Jacoby LB, Gusella JF, Ramesh V, Louis DN. Universal absence of merlin, but not other ERM family members, in schwannomas. The American Journal of Pathology. 151: 1649-54. PMID 9403715  0.695
1997 Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN. Chromosomal localization to 19q13.3, partial genomic structure and 5' cDNA sequence of the human symplekin gene. Somatic Cell and Molecular Genetics. 23: 229-31. PMID 9330635 DOI: 10.1007/Bf02721375  0.501
1997 Jones RM, MacDonald ME, Branda J, Altherr MR, Louis DN, Schmidt EV. Assignment of the human gene encoding eukaryotic initiation factor 4E (EIF4E) to the region q21-25 on chromosome 4. Somatic Cell and Molecular Genetics. 23: 221-3. PMID 9330633 DOI: 10.1007/Bf02721373  0.316
1997 Maintz D, Fiedler K, Koopmann J, Rollbrocker B, Nechev S, Lenartz D, Stangl AP, Louis DN, Schramm J, Wiestler OD, von Deimling A. Molecular genetic evidence for subtypes of oligoastrocytomas. Journal of Neuropathology and Experimental Neurology. 56: 1098-104. PMID 9329453 DOI: 10.1097/00005072-199710000-00003  0.421
1997 Meyer-Puttlitz B, Hayashi Y, Waha A, Rollbrocker B, Boström J, Wiestler OD, Louis DN, Reifenberger G, von Deimling A. Molecular genetic analysis of giant cell glioblastomas. The American Journal of Pathology. 151: 853-7. PMID 9284834  0.324
1997 Hsu DW, Louis DN, Efird JT, Hedley-Whyte ET. Use of MIB-1 (Ki-67) immunoreactivity in differentiating grade II and grade III gliomas. Journal of Neuropathology and Experimental Neurology. 56: 857-65. PMID 9258255  0.641
1997 Stemmer-Rachamimov AO, Louis DN. Histopathologic and immunohistochemical prognostic factors in malignant gliomas. Current Opinion in Oncology. 9: 230-4. PMID 9229144 DOI: 10.1097/00001622-199709030-00003  0.679
1997 Ono Y, Tamiya T, Ichikawa T, Matsumoto K, Furuta T, Ohmoto T, Akiyama K, Seki S, Ueki K, Louis DN. Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression. Acta Neuropathologica. 94: 21-7. PMID 9224526 DOI: 10.1007/S004010050667  0.532
1997 Chung DC, Smith AP, Louis DN, Graeme-Cook F, Warshaw AL, Arnold A. A novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications. The Journal of Clinical Investigation. 100: 404-10. PMID 9218518 DOI: 10.1172/Jci119547  0.465
1997 Hayashi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A. Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathology (Zurich, Switzerland). 7: 871-5. PMID 9217972 DOI: 10.1111/J.1750-3639.1997.Tb00890.X  0.549
1997 Platten M, Meyer-Puttlitz B, Blümcke I, Waha A, Wolf HK, Nöthen MM, Louis DN, Sampson JR, von Deimling A. A novel splice site associated polymorphism in the tuberous sclerosis 2 (TSC2) gene may predispose to the development of sporadic gangliogliomas. Journal of Neuropathology and Experimental Neurology. 56: 806-10. PMID 9210877 DOI: 10.1097/00005072-199756070-00007  0.566
1997 Stemmer-Rachamimov AO, Gonzalez-Agosti C, Xu L, Burwick JA, Beauchamp R, Pinney D, Louis DN, Ramesh V. Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system. Journal of Neuropathology and Experimental Neurology. 56: 735-42. PMID 9184664 DOI: 10.1097/00005072-199756060-00011  0.668
1997 Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. Journal of Neuropathology and Experimental Neurology. 56: 485-9. PMID 9143261 DOI: 10.1097/00005072-199705000-00004  0.744
1997 Burns KL, Ueki K, Louis DN. MOLECULAR GENETIC AND IMMUNOHISTOCHEMICAL ANALYSIS OF THE p16-cdk4-pRb PATHWAY IN GLIOBLASTOMAS Journal of Neuropathology and Experimental Neurology. 56: 581. DOI: 10.1097/00005072-199705000-00053  0.493
1996 Rosenberg JE, Lisle DK, Burwick JA, Ueki K, von Deimling A, Mohrenweiser HW, Louis DN. Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene. 13: 2483-5. PMID 8957092  0.517
1996 Ono Y, Tamiya T, Ichikawa T, Kunishio K, Matsumoto K, Furuta T, Ohmoto T, Ueki K, Louis DN. Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices. Journal of Neuropathology and Experimental Neurology. 55: 1026-31. PMID 8857999 DOI: 10.1097/00005072-199655100-00002  0.58
1996 Paulus W, Lisle DK, Tonn JC, Wolf HK, Roggendorf W, Reeves SA, Louis DN. Molecular genetic alterations in pleomorphic xanthoastrocytoma. Acta Neuropathologica. 91: 293-7. PMID 8834542 DOI: 10.1007/S004010050428  0.435
1996 Ono Y, Ueki K, Joseph JT, Louis DN. Homozygous deletions of the CDKN2/p16 gene in dural hemangiopericytomas. Acta Neuropathologica. 91: 221-5. PMID 8834533 DOI: 10.1007/S004010050419  0.782
1996 Kim L, Hochberg FH, Thornton AF, Harsh GR, Patel H, Finkelstein D, Louis DN. Procarbazine, lomustine, and vincristine (PCV) chemotherapy for grade III and grade IV oligoastrocytomas. Journal of Neurosurgery. 85: 602-7. PMID 8814163 DOI: 10.3171/Jns.1996.85.4.0602  0.313
1996 Rollbrocker B, Waha A, Louis DN, Wiestler OD, von Deimling A. Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme. Acta Neuropathologica. 92: 70-4. PMID 8811128 DOI: 10.1007/S004010050491  0.408
1996 Rainov NG, Kramm CM, Aboody-Guterman K, Chase M, Ueki K, Louis DN, Harsh GR, Chiocca A, Breakefield XO. Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm. Cancer Gene Therapy. 3: 99-106. PMID 8729908  0.497
1996 Platten M, Giordano MJ, Dirven CM, Gutmann DH, Louis DN. Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas. The American Journal of Pathology. 149: 621-7. PMID 8702000  0.5
1996 Reeves SA, Ueki K, Sinha B, Difiglia M, Louis DN. Regional expression and subcellular localization of the tyrosine-specific phosphatase SH-PTP2 in the adult human nervous system. Neuroscience. 71: 1037-42. PMID 8684607 DOI: 10.1016/0306-4522(95)00491-2  0.452
1996 Chou D, Miyashita T, Mohrenweiser HW, Ueki K, Kastury K, Druck T, von Deimling A, Huebner K, Reed JC, Louis DN. The BAX gene maps to the glioma candidate region at 19q13.3, but is not altered in human gliomas. Cancer Genetics and Cytogenetics. 88: 136-40. PMID 8640722 DOI: 10.1016/0165-4608(95)00341-X  0.571
1996 Ueki K, Ono Y, Henson JW, Efird JT, von Deimling A, Louis DN. CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Research. 56: 150-3. PMID 8548755  0.518
1996 Louis DN, Rosenberg JE, Ueki K, Lisle DK, Burwick JA. THE CHROMOSOME 19Q OLIOMA TUMOR SUPPRESSOR GENE Journal of Neuropathology and Experimental Neurology. 55: 606. DOI: 10.1097/00005072-199605000-00018  0.559
1995 Yong WH, Ueki K, Chou D, Reeves SA, von Deimling A, Gusella JF, Mohrenweiser HW, Buckler AJ, Louis DN. Cloning of a highly conserved human protein serine-threonine phosphatase gene from the glioma candidate region on chromosome 19q13.3. Genomics. 29: 533-6. PMID 8666404 DOI: 10.1006/Geno.1995.9972  0.683
1995 von Deimling A, Louis DN, Wiestler OD. Molecular pathways in the formation of gliomas. Glia. 15: 328-38. PMID 8586467 DOI: 10.1002/Glia.440150312  0.479
1995 Marchuk DA, Gallione CJ, Morrison LA, Clericuzio CL, Hart BL, Kosofsky BE, Louis DN, Gusella JF, Davis LE, Prenger VL. A locus for cerebral cavernous malformations maps to chromosome 7q in two families. Genomics. 28: 311-4. PMID 8530042 DOI: 10.1006/Geno.1995.1147  0.302
1995 Tatter SB, Borges LF, Louis DN. Correction: central neurocytomas of the cervical spinal cord. Journal of Neurosurgery. 82: 706. PMID 7897547  0.542
1995 Kraus JA, Koopmann J, Kaskel P, Maintz D, Brandner S, Schramm J, Louis DN, Wiestler OD, von Deimling A. Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. Journal of Neuropathology and Experimental Neurology. 54: 91-5. PMID 7815084 DOI: 10.1097/00005072-199501000-00011  0.438
1995 Raffel C, Ueki K, Harsh GR, Louis DN. The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor. Neurosurgery. 36: 971-4; discussion 97. PMID 7791990 DOI: 10.1227/00006123-199505000-00013  0.6
1995 Weissmann DJ, Ferry JA, Harris NL, Louis DN, Delmonico F, Spiro I. Posttransplantation lymphoproliferative disorders in solid organ recipients are predominantly aggressive tumors of host origin. American Journal of Clinical Pathology. 103: 748-55. PMID 7785662 DOI: 10.1093/Ajcp/103.6.748  0.328
1995 von Deimling A, Kraus JA, Stangl AP, Wellenreuther R, Lenartz D, Schramm J, Louis DN, Ramesh V, Gusella JF, Wiestler OD. Evidence for subarachnoid spread in the development of multiple meningiomas. Brain Pathology (Zurich, Switzerland). 5: 11-4. PMID 7767486 DOI: 10.1111/J.1750-3639.1995.Tb00571.X  0.451
1995 Louis DN, Ramesh V, Gusella JF. Neuropathology and molecular genetics of neurofibromatosis 2 and related tumors. Brain Pathology (Zurich, Switzerland). 5: 163-72. PMID 7670657 DOI: 10.1111/J.1750-3639.1995.Tb00590.X  0.41
1995 Louis DN, von Deimling A. Hereditary tumor syndromes of the nervous system: overview and rare syndromes. Brain Pathology (Zurich, Switzerland). 5: 145-51. PMID 7670655 DOI: 10.1111/J.1750-3639.1995.Tb00588.X  0.368
1995 Yong WH, Chou D, Ueki K, Harsh GR, von Deimling A, Gusella JF, Mohrenweiser HW, Louis DN. Chromosome 19q deletions in human gliomas overlap telomeric to D19S219 and may target a 425 kb region centromeric to D19S112. Journal of Neuropathology and Experimental Neurology. 54: 622-6. PMID 7666049 DOI: 10.1097/00005072-199509000-00002  0.685
1995 Yong WH, Raffel C, von Deimling A, Louis DN. The APC gene in Turcot's syndrome. The New England Journal of Medicine. 333: 524. PMID 7662026 DOI: 10.1056/Nejm199508243330817  0.499
1995 Koopmann J, Maintz D, Schild S, Schramm J, Louis DN, Wiestler OD, von Deimling A. Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours. British Journal of Cancer. 72: 1230-3. PMID 7577473 DOI: 10.1038/Bjc.1995.491  0.368
1995 Joseph JT, Lisle DK, Jacoby LB, Paulus W, Barone R, Cohen ML, Roggendorf WH, Bruner JM, Gusella JF, Louis DN. NF2 gene analysis distinguishes hemangiopericytoma from meningioma. The American Journal of Pathology. 147: 1450-5. PMID 7485407  0.745
1995 Louis DN, Gusella JF. A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends in Genetics : Tig. 11: 412-5. PMID 7482768 DOI: 10.1016/S0168-9525(00)89125-8  0.349
1995 Joseph JT, Lisle DK, Louis DN. NF2 GENE ANALYSIS IN HEMANGIOPERICYTOMAS AND MENINGIOMAS Journal of Neuropathology and Experimental Neurology. 54: 467. DOI: 10.1097/00005072-199505000-00241  0.706
1995 Yong WH, Chou D, Ueki K, von Deimling A, Louis DN. THE CHROMOSOME 19q GLIOMA TUMOR SUPPRESSOR GENE Journal of Neuropathology and Experimental Neurology. 54: 439. DOI: 10.1097/00005072-199505000-00130  0.608
1995 Lachance DH, Schaefer PW, Hedley-Whyte ET, Stakes JW, Louis DN. A 43-year-old man with multifocal neurologic problems and confusion New England Journal of Medicine. 333: 992-999. DOI: 10.1056/Nejm199510123331509  0.608
1994 Louis DN. The p53 gene and protein in human brain tumors. Journal of Neuropathology and Experimental Neurology. 53: 11-21. PMID 8301315 DOI: 10.1097/00005072-199401000-00002  0.423
1994 Rubio MP, Correa KM, Ramesh V, MacCollin MM, Jacoby LB, von Deimling A, Gusella JF, Louis DN. Analysis of the neurofibromatosis 2 gene in human ependymomas and astrocytomas. Cancer Research. 54: 45-7. PMID 8261460  0.311
1994 Cryns VL, Rubio MP, Thor AD, Louis DN, Arnold A. p53 abnormalities in human parathyroid carcinoma. The Journal of Clinical Endocrinology and Metabolism. 78: 1320-4. PMID 8200932 DOI: 10.1210/Jcem.78.6.8200932  0.421
1994 von Deimling A, Nagel J, Bender B, Lenartz D, Schramm J, Louis DN, Wiestler OD. Deletion mapping of chromosome 19 in human gliomas. International Journal of Cancer. Journal International Du Cancer. 57: 676-80. PMID 8194874 DOI: 10.1002/Ijc.2910570511  0.4
1994 Rubio MP, Correa KM, Ueki K, Mohrenweiser HW, Gusella JF, von Deimling A, Louis DN. The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC. Cancer Research. 54: 4760-3. PMID 8062276  0.505
1994 Miller DC, Hochberg FH, Harris NL, Gruber ML, Louis DN, Cohen H. Pathology with clinical correlations of primary central nervous system non-Hodgkin's lymphoma. The Massachusetts General Hospital experience 1958-1989. Cancer. 74: 1383-97. PMID 8055462 DOI: 10.1002/1097-0142(19940815)74:4<1383::Aid-Cncr2820740432>3.0.Co;2-1  0.524
1994 Golden JA, Louis DN. Images in clinical medicine. Acute bacterial meningitis. The New England Journal of Medicine. 331: 364. PMID 8028617 DOI: 10.1056/NEJM199408113310605  0.512
1994 Tatter SB, Borges LF, Louis DN. Central neurocytomas of the cervical spinal cord. Report of two cases. Journal of Neurosurgery. 81: 288-93. PMID 8027814 DOI: 10.3171/Jns.1994.81.2.0288  0.641
1994 Jacoby LB, MacCollin M, Louis DN, Mohney T, Rubio MP, Pulaski K, Trofatter JA, Kley N, Seizinger B, Ramesh V. Exon scanning for mutation of the NF2 gene in schwannomas. Human Molecular Genetics. 3: 413-9. PMID 8012353 DOI: 10.1093/Hmg/3.3.413  0.323
1994 Henson JW, Schnitker BL, Correa KM, von Deimling A, Fassbender F, Xu HJ, Benedict WF, Yandell DW, Louis DN. The retinoblastoma gene is involved in malignant progression of astrocytomas. Annals of Neurology. 36: 714-21. PMID 7979217 DOI: 10.1002/Ana.410360505  0.476
1994 Ueki K, Richardson EP, Henson JW, Louis DN. In situ polymerase chain reaction demonstration of JC virus in progressive multifocal leukoencephalopathy, including an index case. Annals of Neurology. 36: 670-3. PMID 7944303 DOI: 10.1002/Ana.410360421  0.464
1994 Tatter SB, Ogilvy CS, Golden JA, Ojemann RG, Louis DN. Third ventricular xanthogranulomas clinically and radiologically mimicking colloid cysts. Report of two cases. Journal of Neurosurgery. 81: 605-9. PMID 7931596 DOI: 10.3171/Jns.1994.81.4.0605  0.724
1994 Xu L, Sgroi D, Sterner CJ, Beauchamp RL, Pinney DM, Keel S, Ueki K, Rutter JL, Buckler AJ, Louis DN. Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas. Cancer Research. 54: 5262-4. PMID 7923151  0.495
1994 MacCollin M, Ramesh V, Jacoby LB, Louis DN, Rubio MP, Pulaski K, Trofatter JA, Short MP, Bove C, Eldridge R. Mutational analysis of patients with neurofibromatosis 2. American Journal of Human Genetics. 55: 314-20. PMID 7913580  0.603
1994 Ueki K, Rubio MP, Ramesh V, Correa KM, Rutter JL, von Deimling A, Buckler AJ, Gusella JF, Louis DN. MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p. Human Molecular Genetics. 3: 1841-5. PMID 7849711 DOI: 10.1093/Hmg/3.10.1841  0.587
1994 Louis DN, Hedley-Whyte ET. Workshop 5: The Genetic Basis of Human Brain Tumors: An Update Brain Pathology. 4: 317-319. DOI: 10.1111/J.1750-3639.1994.Tb00914.X  0.358
1993 Louis DN, von Deimling A, Chung RY, Rubio MP, Whaley JM, Eibl RH, Ohgaki H, Wiestler OD, Thor AD, Seizinger BR. Comparative study of p53 gene and protein alterations in human astrocytic tumors. Journal of Neuropathology and Experimental Neurology. 52: 31-8. PMID 8381161 DOI: 10.1097/00005072-199301000-00005  0.424
1993 Burnstine MA, Levin LA, Louis DN, Hedley-Whyte ET, Kupsky WJ, Doepner D, Albert DM. Nucleolar organizer regions in optic gliomas. Brain : a Journal of Neurology. 116: 1465-76. PMID 8293281 DOI: 10.1093/Brain/116.6.1465  0.639
1993 von Deimling A, von Ammon K, Schoenfeld D, Wiestler OD, Seizinger BR, Louis DN. Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathology (Zurich, Switzerland). 3: 19-26. PMID 8269081 DOI: 10.1111/J.1750-3639.1993.Tb00721.X  0.39
1993 von Deimling A, Louis DN, Menon AG, von Ammon K, Petersen I, Ellison D, Wiestler OD, Seizinger BR. Deletions on the long arm of chromosome 17 in pilocytic astrocytoma. Acta Neuropathologica. 86: 81-5. PMID 8103960 DOI: 10.1007/Bf00454903  0.444
1993 Louis DN, Rubio MP, Correa KM, Gusella JF, von Deimling A. Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens. Journal of Neuropathology and Experimental Neurology. 52: 507-15. PMID 8103086 DOI: 10.1097/00005072-199309000-00009  0.456
1993 Centeno BA, Louis DN, Kupsky WJ, Preffer FI, Sobel RA. The AgNOR technique, PCNA immunohistochemistry, and DNA ploidy in the evaluation of choroid plexus biopsy specimens. American Journal of Clinical Pathology. 100: 690-6. PMID 7902669 DOI: 10.1093/Ajcp/100.6.690  0.514
1993 von Deimling A, Bender B, Louis DN, Wiestler OD. A rapid and non-radioactive PCR based assay for the detection of allelic loss in human gliomas. Neuropathology and Applied Neurobiology. 19: 524-9. PMID 7510049 DOI: 10.1111/J.1365-2990.1993.Tb00481.X  0.323
1993 Rubio M, Louis DN. ACCUMULATION OF WILD-TYPE P53 PROTEIN IN ASTROCYTOMAS IS NOT MEDIATED BY MDM2 GENE AMPLIFICATION Journal of Neuropathology and Experimental Neurology. 52: 323. DOI: 10.1097/00005072-199305000-00252  0.43
1993 Louis DN. Molecular genetics of nervous system tumors Trends in Genetics. 9: 326. DOI: 10.1016/0168-9525(93)90252-D  0.376
1992 Louis DN, Arriagada PV, Hyman BT, Hedley-Whyte ET. Olfactory dysgenesis or hypoplasia: a variant in the arhinencephaly spectrum? Neurology. 42: 179-82. PMID 1734299 DOI: 10.1212/Wnl.42.1.179  0.665
1992 Glass J, Hochberg FH, Gruber ML, Louis DN, Smith D, Rattner B. The treatment of oligodendrogliomas and mixed oligodendroglioma-astrocytomas with PCV chemotherapy. Journal of Neurosurgery. 76: 741-5. PMID 1564535 DOI: 10.3171/Jns.1992.76.5.0741  0.339
1992 Louis DN, Meehan SM, Ferrante RJ, Hedley-Whyte ET. Use of the silver nucleolar organizer region (AgNOR) technique in the differential diagnosis of central nervous system neoplasia. Journal of Neuropathology and Experimental Neurology. 51: 150-7. PMID 1538239  0.645
1992 Louis DN, von Deimling A, Dickersin GR, Dooling EC, Seizinger BR. Desmoplastic cerebral astrocytomas of infancy: a histopathologic, immunohistochemical, ultrastructural, and molecular genetic study. Human Pathology. 23: 1402-9. PMID 1468778 DOI: 10.1016/0046-8177(92)90061-7  0.453
1992 von Deimling A, Louis DN, von Ammon K, Petersen I, Wiestler OD, Seizinger BR. Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas. Cancer Research. 52: 4277-9. PMID 1353411  0.331
1992 von Deimling A, Louis DN, von Ammon K, Petersen I, Hoell T, Chung RY, Martuza RL, Schoenfeld DA, YaÅŸargil MG, Wiestler OD. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. Journal of Neurosurgery. 77: 295-301. PMID 1320666 DOI: 10.3171/Jns.1992.77.2.0295  0.39
1991 Louis DN, Hamilton AJ, Sobel RA, Ojemann RG. Pseudopsammomatous meningioma with elevated serum carcinoembryonic antigen: a true secretory meningioma. Case report. Journal of Neurosurgery. 74: 129-32. PMID 1984492 DOI: 10.3171/Jns.1991.74.1.0129  0.562
1991 Black PM, Louis DN. Case 23-1991 The New England Journal of Medicine. 324: 1651-1659. PMID 1851540 DOI: 10.1056/Nejm199106063242308  0.311
1991 Chung R, Whaley J, Kley N, Anderson K, Louis D, Menon A, Hettlich C, Freiman R, Hedley-Whyte ET, Martuza R. TP53 gene mutations and 17p deletions in human astrocytomas. Genes, Chromosomes & Cancer. 3: 323-31. PMID 1686725 DOI: 10.1002/Gcc.2870030502  0.742
1991 Louis DN, Edgerton S, Thor AD, Hedley-Whyte ET. Proliferating cell nuclear antigen and Ki-67 immunohistochemistry in brain tumors: a comparative study. Acta Neuropathologica. 81: 675-9. PMID 1679278 DOI: 10.1007/Bf00296379  0.694
1991 Arriagada PV, Louis DN, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles and olfactory dysgenesis. Lancet. 337: 559. PMID 1671925 DOI: 10.1016/0140-6736(91)91351-T  0.645
1990 Miralbell R, Louis DN, O'Keeffe D, Rosenberg AE, Suit HD. Metastatic ependymoma of the sacrum. Cancer. 65: 2353-2355. PMID 2346920 DOI: 10.1002/1097-0142(19900515)65:10<2353::Aid-Cncr2820651032>3.0.Co;2-D  0.352
1990 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma: a follow-up study of sarcomatous dedifferentiation. Acta Neuropathologica. 80: 573-4. PMID 2251917 DOI: 10.1007/Bf00294623  0.632
1990 Louis DN, Hochberg FH. Cerebral primitive neuroectodermal tumor in an adult, with spinal cord metastasis after 18-year dormancy. Journal of Neuro-Oncology. 9: 77-80. PMID 2170592 DOI: 10.1007/Bf00167072  0.336
1990 Louis DN, Swearingen B, Linggood RM, Dickersin GR, Kretschmar C, Bhan AK, Hedley-Whyte ET. Central nervous system neurocytoma and neuroblastoma in adults--report of eight cases. Journal of Neuro-Oncology. 9: 231-8. PMID 2086738 DOI: 10.1007/Bf02341154  0.697
1990 Louis DN, Edgerton S, Thor AD, Hediev-Whyte ET. PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN HUMAN NERVOUS SYSTEM TUMORS Journal of Neuropathology and Experimental Neurology. 49: 272. DOI: 10.1097/00005072-199005000-00040  0.364
1989 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma. Acta Neuropathologica. 78: 332-5. PMID 2763807 DOI: 10.1007/Bf00687765  0.697
1989 Louis DN, Richardson EP, Dickersin GR, Petrucci DA, Rosenberg AE, Ojemann RG. Primary intracranial leiomyosarcoma. Case report. Journal of Neurosurgery. 71: 279-82. PMID 2746352 DOI: 10.3171/Jns.1989.71.2.0279  0.329
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