| Year |
Citation |
Score |
| 2024 |
Pundavela J, Dinglasan SA, Touvron M, Hummel SA, Hu L, Rizvi TA, Choi K, Hildeman DA, Ratner N. Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance. Science Advances. 10: eado6342. PMID 39413183 DOI: 10.1126/sciadv.ado6342 |
0.366 |
|
| 2024 |
Patritti-Cram J, Rahrmann EP, Rizvi TA, Scheffer KC, Phoenix TN, Largaespada DA, Ratner N. NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14. Iscience. 27: 110294. PMID 39100928 DOI: 10.1016/j.isci.2024.110294 |
0.403 |
|
| 2024 |
Williams KB, Larsson AT, Keller BJ, Chaney KE, Williams RL, Bhunia MM, Draper GM, Jubenville TA, Rathe SK, Moertel CL, Ratner N, Largaespada DA. Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors. Biorxiv : the Preprint Server For Biology. PMID 38585724 DOI: 10.1101/2024.03.25.585959 |
0.393 |
|
| 2024 |
Perrino MR, Ahmari N, Hall A, Jackson M, Na Y, Pundavela J, Szabo S, Woodruff TM, Dombi E, Kim MO, Köhl J, Wu J, Ratner N. C5aR plus MEK inhibition durably targets the tumor milieu and reveals tumor cell phagocytosis. Life Science Alliance. 7. PMID 38458648 DOI: 10.26508/lsa.202302229 |
0.403 |
|
| 2024 |
Raut NG, Maile LA, Oswalt LM, Mitxelena I, Adlakha A, Sprague KL, Rupert AR, Bokros L, Hofmann MC, Patritti-Cram J, Rizvi TA, Queme LF, Choi K, Ratner N, Jankowski MP. Schwann cells modulate nociception in neurofibromatosis 1. Jci Insight. 9. PMID 38258905 DOI: 10.1172/jci.insight.171275 |
0.343 |
|
| 2023 |
Pillay-Smiley N, Fletcher JS, de Blank P, Ratner N. Shedding New Light: Novel Therapies for Common Disorders in Children with Neurofibromatosis Type I. Pediatric Clinics of North America. 70: 937-950. PMID 37704352 DOI: 10.1016/j.pcl.2023.05.007 |
0.322 |
|
| 2023 |
González-Muñoz T, Di Giannatale A, Garcia-Silva S, Santos V, Sanchez-Redondo S, Savini C, Graña-Castro O, Blanco-Aparicio C, Fischer S, De Wever O, Creus-Bachiller E, Ortega-Bertran S, Pisapia DJ, Rodríguez-Peralto JL, Fernández-Rodríguez J, ... ... Ratner N, et al. Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37432984 DOI: 10.1158/1078-0432.CCR-22-2462 |
0.348 |
|
| 2023 |
Jackson M, Ahmari N, Wu J, Rizvi TA, Fugate E, Kim MO, Dombi E, Arnhof H, Boehmelt G, Düchs MJ, Long CJ, Maier U, Trapani F, Hofmann MH, Ratner N. . The Journal of Pharmacology and Experimental Therapeutics. PMID 36849412 DOI: 10.1124/jpet.122.001431 |
0.432 |
|
| 2023 |
Magallón-Lorenz M, Terribas E, Ortega-Bertran S, Creus-Bachiller E, Fernández M, Requena G, Rosas I, Mazuelas H, Uriarte-Arrazola I, Negro A, Lausová T, Castellanos E, Blanco I, DeVries G, Kawashima H, ... ... Ratner N, et al. Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis. Iscience. 26: 106096. PMID 36818284 DOI: 10.1016/j.isci.2023.106096 |
0.409 |
|
| 2023 |
Na Y, Hall A, Yu Y, Hu L, Choi K, Burgard JA, Szabo S, Huang G, Ratner N, Wu J. Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis. Oncogene. PMID 36759572 DOI: 10.1038/s41388-023-02620-x |
0.4 |
|
| 2022 |
Kershner LJ, Choi K, Wu J, Zhang X, Perrino M, Salomonis N, Shern JF, Ratner N. Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment. Jci Insight. 7. PMID 36134665 DOI: 10.1172/jci.insight.154513 |
0.411 |
|
| 2022 |
Patritti Cram J, Wu J, Coover RA, Rizvi TA, Chaney KE, Ravindran R, Cancelas JA, Spinner RJ, Ratner N. P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis. Elife. 11. PMID 35311647 DOI: 10.7554/eLife.73511 |
0.419 |
|
| 2021 |
Thomson CS, Pundavela J, Perrino MR, Coover RA, Choi K, Chaney KE, Rizvi TA, Largaespada DA, Ratner N. WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth. Oncogene. PMID 34079083 DOI: 10.1038/s41388-021-01773-x |
0.462 |
|
| 2021 |
Vélez-Reyes GL, Koes N, Ryu JH, Kaufmann G, Berner M, Weg MT, Wolf NK, Rathe SK, Ratner N, Moriarity BS, Largaespada DA. Transposon Mutagenesis-Guided CRISPR/Cas9 Screening Strongly Implicates Dysregulation of Hippo/YAP Signaling in Malignant Peripheral Nerve Sheath Tumor Development. Cancers. 13. PMID 33808166 DOI: 10.3390/cancers13071584 |
0.486 |
|
| 2021 |
Patritti-Cram J, Coover RA, Jankowski MP, Ratner N. Purinergic signaling in peripheral nervous system glial cells. Glia. PMID 33507559 DOI: 10.1002/glia.23969 |
0.367 |
|
| 2020 |
Watson AL, Keller BJ, Williams KA, Damle NN, Finnerty SJ, Anderson LK, Greeley AD, Keng VW, Rahrmann EP, Halfond AL, Powell NM, Collins MH, Rizvi T, Moertel CL, Ratner N, et al. Correction: Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity. Oncotarget. 11: 3618-3620. PMID 33062197 DOI: 10.18632/oncotarget.27349 |
0.325 |
|
| 2020 |
Asleh J, Shofty B, Cohen N, Kavushansky A, López-Juárez A, Constantini S, Ratner N, Kahn I. Brain-wide structural and functional disruption in mice with oligodendrocyte-specific deletion is rescued by inhibition of nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. PMID 32839340 DOI: 10.1073/Pnas.2008391117 |
0.604 |
|
| 2020 |
Chaney KE, Perrino MR, Kershner LJ, Patel AV, Wu J, Choi K, Rizvi TA, Dombi E, Szabo S, Largaespada DA, Ratner N. Cdkn2a loss in a model of neurofibroma demonstrates stepwise tumor progression to atypical neurofibroma and MPNST. Cancer Research. PMID 32816910 DOI: 10.1158/0008-5472.Can-19-1429 |
0.532 |
|
| 2020 |
Fletcher JS, Pundavela J, Ratner N. After loss in Schwann cells, inflammation drives neurofibroma formation. Neuro-Oncology Advances. 2: i23-i32. PMID 32642730 DOI: 10.1093/noajnl/vdz045 |
0.415 |
|
| 2020 |
Ma Y, Gross AM, Dombi E, Pemov A, Choi K, Chaney K, Rhodes SD, Angus SP, Sciaky N, Clapp DW, Ratner N, Widemann BC, Rios JJ, Elefteriou F. A molecular basis for neurofibroma-associated skeletal manifestations in NF1. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32601387 DOI: 10.1038/S41436-020-0885-3 |
0.4 |
|
| 2020 |
Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia Telletxea N, Medrano D, Fernández-Ramos D, Lozano JJ, Okawa S, Lavín JL, Martin-Martin N, Sutherland JD, ... ... Ratner N, et al. HuR/ELAVL1 drives malignant peripheral nerve sheath tumour growth and metastasis. The Journal of Clinical Investigation. PMID 32315290 DOI: 10.1172/Jci130379 |
0.483 |
|
| 2020 |
Heinrich A, Potter SJ, Guo L, Ratner N, DeFalco T. Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. Cell Reports. 31: 107513. PMID 32294451 DOI: 10.1016/j.celrep.2020.03.077 |
0.328 |
|
| 2020 |
Guo J, Chaney KE, Choi K, Witek G, Patel AV, Xie H, Lin D, Whig K, Xiong Y, Schultz DC, Ratner N, Field J. Polo-like kinase 1 as a therapeutic target for malignant peripheral nerve sheath tumors (MPNST) and schwannomas. American Journal of Cancer Research. 10: 856-869. PMID 32266095 |
0.409 |
|
| 2020 |
Fletcher JS, Wu J, Jessen WJ, Pundavela J, Dombi E, Kim M, Rizvi TA, Chetal K, Salomonis N, Ratner N. Abstract B32: Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-B32 |
0.487 |
|
| 2019 |
Isfort I, Elges S, Cyra M, Berthold R, Renner M, Mechtersheimer G, Åman P, Larsson O, Ratner N, Hafner S, Simmet T, Schliemann C, Rossig C, Dirksen U, Grünewald I, et al. Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone. Scientific Reports. 9: 19704. PMID 31873172 DOI: 10.1038/s41598-019-56247-8 |
0.473 |
|
| 2019 |
Gripp KW, Schill L, Schoyer L, Stronach B, Bennett AM, Blaser S, Brown A, Burdine R, Burkitt-Wright E, Castel P, Darilek S, Dias A, Dyer T, Ellis M, Erickson G, ... ... Ratner N, et al. The sixth international RASopathies symposium: Precision medicine-From promise to practice. American Journal of Medical Genetics. Part A. PMID 31825160 DOI: 10.1002/Ajmg.A.61434 |
0.332 |
|
| 2019 |
Yu Y, Choi K, Wu J, Andreassen PR, Dexheimer PJ, Keddache M, Brems H, Spinner RJ, Cancelas JA, Martin LJ, Wallace MR, Legius E, Vogel KS, Ratner N. NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation. Acta Neuropathologica. PMID 31664505 DOI: 10.1007/s00401-019-02086-w |
0.462 |
|
| 2019 |
Rice FL, Houk G, Wymer JP, Gosline SJC, Guinney J, Wu J, Ratner N, Jankowski MP, La Rosa S, Dockum M, Storey JR, Carroll SL, Albrecht PJ, Riccardi VM. The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin. Plos One. 14: e0216527. PMID 31107888 DOI: 10.1371/Journal.Pone.0216527 |
0.338 |
|
| 2019 |
Yang J, Ylipää A, Sun Y, Zheng H, Chen K, Nykter M, Trent J, Ratner N, Lev DC, Zhang W. Editor's Note: Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 25: 3195. PMID 31092619 DOI: 10.1158/1078-0432.CCR-19-1144 |
0.308 |
|
| 2019 |
Hall A, Choi K, Liu W, Rose J, Zhao C, Yu Y, Na Y, Cai Y, Coover RA, Lin Y, Dombi E, Kim M, Levanon D, Groner Y, Boscolo E, ... ... Ratner N, et al. RUNX represses to drive neurofibromagenesis. Science Advances. 5: eaau8389. PMID 31032403 DOI: 10.1126/Sciadv.Aau8389 |
0.521 |
|
| 2019 |
Hennigan RF, Fletcher JS, Guard S, Ratner N. Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins. Science Signaling. 12. PMID 31015291 DOI: 10.1126/scisignal.aau8749 |
0.369 |
|
| 2019 |
Ramkissoon A, Chaney KE, Milewski D, Williams KB, Williams RL, Choi K, Miller AA, Kalin TV, Pressey JG, Szabo S, Azam M, Largaespada DA, Ratner N. Targeted inhibition of the dual specificity phosphatases DUSP1 and DUSP6 suppress MPNST growth via JNK. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30936125 DOI: 10.1158/1078-0432.Ccr-18-3224 |
0.575 |
|
| 2019 |
Rauen KA, Alsaegh A, Ben-Shachar S, Berman Y, Blakeley J, Cordeiro I, Elgersma Y, Evans DG, Fisher MJ, Frayling IM, George J, Huson SM, Kerr B, Khire U, Korf B, ... ... Ratner N, et al. First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics. American Journal of Medical Genetics. Part A. PMID 30908877 DOI: 10.1002/Ajmg.A.61125 |
0.351 |
|
| 2019 |
Fletcher JS, Wu J, Jessen WJ, Pundavela J, Miller JA, Dombi E, Kim MO, Rizvi TA, Chetal K, Salomonis N, Ratner N. Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice. Jci Insight. 4. PMID 30728335 DOI: 10.1172/Jci.Insight.98601 |
0.507 |
|
| 2019 |
Osum S, Stemmer-Rachamimov A, Widemann B, Dombi E, Vitte J, Dahiya S, Rizvi T, Ratner N, Messiaen L, Gutmann D, Giovannini M, Moertel C, Largaespada D, Watson A. TMOD-23. PRECLINICAL DRUG EVALUATION IN A GENETICALLY ENGINEERED MINIPIG MODEL OF NEUROFIBROMATOSIS TYPE 1 Neuro-Oncology. 21: vi267-vi267. DOI: 10.1093/Neuonc/Noz175.1122 |
0.446 |
|
| 2018 |
Fletcher JS, Springer MG, Choi K, Jousma E, Rizvi TA, Dombi E, Kim MO, Wu J, Ratner N. STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma. Oncogene. PMID 30542122 DOI: 10.1038/S41388-018-0600-X |
0.541 |
|
| 2018 |
Coover RA, Healy TE, Guo L, Chaney KE, Hennigan RF, Thomson CS, Aschbacher-Smith LE, Jankowski MP, Ratner N. Tonic ATP-mediated growth suppression in peripheral nerve glia requires arrestin-PP2 and is evaded in NF1. Acta Neuropathologica Communications. 6: 127. PMID 30470263 DOI: 10.1186/S40478-018-0635-9 |
0.49 |
|
| 2018 |
Agresta L, Salloum R, Hummel TR, Ratner N, Mangano FT, Fuller C, McMasters RL, Pater L, Jones BV, Szabo S, Pressey JG. Malignant peripheral nerve sheath tumor: Transformation in a patient with neurofibromatosis type 2. Pediatric Blood & Cancer. e27520. PMID 30408304 DOI: 10.1002/pbc.27520 |
0.471 |
|
| 2018 |
Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, et al. Defective transcription elongation in a subset of cancers confers immunotherapy resistance. Nature Communications. 9: 4410. PMID 30353012 DOI: 10.1038/S41467-018-06810-0 |
0.405 |
|
| 2018 |
Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, ... ... Ratner N, et al. Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. American Journal of Medical Genetics. Part A. e40632. PMID 30302932 DOI: 10.1002/Ajmg.A.40632 |
0.401 |
|
| 2018 |
Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, et al. Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Communications Biology. 1: 158. PMID 30302402 DOI: 10.1038/s42003-018-0163-y |
0.317 |
|
| 2018 |
Chhipa RR, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, Chen X, Waclaw R, Chow LM, Khuchua Z, Kofron M, Weirauch MT, Kendler A, McPherson C, Ratner N, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nature Cell Biology. PMID 29915361 DOI: 10.1038/S41556-018-0126-Z |
0.339 |
|
| 2018 |
Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, ... ... Ratner N, et al. 2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. American Journal of Medical Genetics. Part A. 176: 1258-1269. PMID 29681099 DOI: 10.1002/Ajmg.A.38675 |
0.478 |
|
| 2018 |
Allaway RJ, Wood MD, Downey SL, Bouley SJ, Traphagen NA, Wells JD, Batra J, Melancon SN, Ringelberg C, Seibel W, Ratner N, Sanchez Y. Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells. Oncotarget. 9: 15860-15875. PMID 29662612 DOI: 10.18632/Oncotarget.19335 |
0.54 |
|
| 2018 |
Wu LMN, Deng Y, Wang J, Zhao C, Wang J, Rao R, Xu L, Zhou W, Choi K, Rizvi TA, Remke M, Rubin JB, Johnson RL, Carroll TJ, Stemmer-Rachamimov AO, ... ... Ratner N, et al. Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Cancer Cell. 33: 292-308.e7. PMID 29438698 DOI: 10.1016/J.Ccell.2018.01.005 |
0.556 |
|
| 2018 |
Ratner N. Abstract IA15: Using gene expression analyses to identify MPNST therapeutics Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Ia15 |
0.499 |
|
| 2018 |
Weiss B, Plotkin S, Widemann B, Tonsgard J, Blakeley J, Allen J, Schorry E, Korf B, Rosser T, Goldman S, Vinks A, Cutter G, Dombi E, Ratner N, Packer R, et al. NFM-06. NF106: PHASE 2 TRIAL OF THE MEK INHIBITOR PD-0325901 IN ADOLESCENTS AND ADULTS WITH NF1-RELATED PLEXIFORM NEUROFIBROMAS: AN NF CLINICAL TRIALS CONSORTIUM STUDY Neuro-Oncology. 20: i143-i143. DOI: 10.1093/Neuonc/Noy059.514 |
0.309 |
|
| 2017 |
Haworth KB, Arnold MA, Pierson CR, Choi K, Yeager ND, Ratner N, Roberts RD, Finlay JL, Cripe TP. Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy. Oncotarget. 8: 82037-82048. PMID 29137242 DOI: 10.18632/Oncotarget.18301 |
0.475 |
|
| 2017 |
Reilly KM, Kim A, Blakely J, Ferner RE, Gutmann DH, Legius E, Miettinen MM, Randall RL, Ratner N, Jumbé NL, Bakker A, Viskochil D, Widemann BC, Stewart DR. Neurofibromatosis Type 1-Associated MPNST State of the Science: Outlining a Research Agenda for the Future. Journal of the National Cancer Institute. 109. PMID 29117388 DOI: 10.1093/Jnci/Djx124 |
0.348 |
|
| 2017 |
Maertens O, McCurrach ME, Braun BS, De Raedt T, Epstein I, Huang TQ, Lauchle JO, Lee H, Wu J, Cripe TP, Clapp DW, Ratner N, Shannon K, Cichowski K. A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies. Cancer Research. PMID 28993414 DOI: 10.1158/0008-5472.Can-17-1789 |
0.324 |
|
| 2017 |
Titus HE, López-Juárez A, Silbak SH, Rizvi TA, Bogard M, Ratner N. Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling. Glia. PMID 28856719 DOI: 10.1002/glia.23209 |
0.38 |
|
| 2017 |
Haworth KB, Arnold MA, Pierson CR, Choi K, Yeager ND, Ratner N, Roberts RD, Finlay JL, Cripe TP. Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: Implications for immunotherapy. Oncotarget. PMID 28611304 DOI: 10.18632/oncotarget.18301 |
0.373 |
|
| 2017 |
López-Juárez A, Titus HE, Silbak SH, Pressler JW, Rizvi TA, Bogard M, Bennett MR, Ciraolo G, Williams MT, Vorhees CV, Ratner N. Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior. Cell Reports. 19: 545-557. PMID 28423318 DOI: 10.1016/J.Celrep.2017.03.073 |
0.452 |
|
| 2017 |
Choi K, Komurov K, Fletcher JS, Jousma E, Cancelas JA, Wu J, Ratner N. An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system. Scientific Reports. 7: 43315. PMID 28256556 DOI: 10.1038/srep43315 |
0.486 |
|
| 2017 |
Currier MA, Sprague L, Rizvi TA, Nartker B, Chen CY, Wang PY, Hutzen BJ, Franczek MR, Patel AV, Chaney KE, Streby KA, Ecsedy JA, Conner J, Ratner N, Cripe TP. Aurora A kinase inhibition enhances oncolytic herpes virotherapy through cytotoxic synergy and innate cellular immune modulation. Oncotarget. PMID 28147331 DOI: 10.18632/oncotarget.14885 |
0.395 |
|
| 2017 |
Choi K, Komurov K, Fletcher JS, Jousma E, Cancelas JA, Wu J, Ratner N. Abstract A04: An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A04 |
0.499 |
|
| 2016 |
Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, Whitcomb P, Martin S, Aschbacher-Smith LE, Rizvi TA, Wu J, Ershler R, Wolters P, Therrien J, Glod J, ... ... Ratner N, et al. Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas. The New England Journal of Medicine. 375: 2550-2560. PMID 28029918 DOI: 10.1056/NEJMoa1605943 |
0.345 |
|
| 2016 |
Wu J, Liu W, Williams JP, Ratner N. EGFR-Stat3 signalling in nerve glial cells modifies neurofibroma initiation. Oncogene. PMID 27748759 DOI: 10.1038/onc.2016.386 |
0.48 |
|
| 2016 |
Kendall JJ, Chaney KE, Patel AV, Rizvi TA, Largaespada DA, Ratner N. CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin. Oncotarget. PMID 27448963 DOI: 10.18632/Oncotarget.10668 |
0.472 |
|
| 2016 |
Patel AV, Chaney KE, Choi K, Largaespada DA, Kumar AR, Ratner N. An shRNA screen identifies MEIS1 as a driver of malignant peripheral nerve sheath tumors. Ebiomedicine. PMID 27333032 DOI: 10.1016/J.Ebiom.2016.06.007 |
0.566 |
|
| 2016 |
Ratner N, Brodeur GM, Dale RC, Schor NF. The "Neuro" of Neuroblastoma: Neuroblastoma as a Neurodevelopmental Disorder. Annals of Neurology. PMID 27043043 DOI: 10.1002/Ana.24659 |
0.304 |
|
| 2016 |
Wu J, Keng V, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, ... ... Ratner N, et al. Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation. Cell Reports. PMID 26904939 DOI: 10.1016/J.Celrep.2016.01.074 |
0.791 |
|
| 2016 |
Currier M, Rizvi T, Nartker B, Chen D, Chen C, Wang P, Sprague L, Franczek M, Patel A, Chaney K, Streby K, Ecsedy J, Conner J, Ratner N, Cripe T. Abstract B35: Enhanced antitumor efficacy by combining oncolytic herpes simplex virus and Aurora A kinase inhibition in models of neuroblastoma and malignant peripheral nerve sheath tumor Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B35 |
0.394 |
|
| 2016 |
Haworth KB, Arnold MA, Pierson CR, Choi K, Yeager ND, Ratner N, Finlay JL, Cripe TP. IMST-19. IMMUNE PROFILING OF NF1-ASSOCIATED TUMORS REVEALS DISTINCT DIFFERENCES AMONG HISTOLOGIC SUBTYPES AND POTENTIAL FOR PATIENT-SPECIFIC SELECTION OF IMMUNOTHERAPY Neuro-Oncology. 18: vi90-vi90. DOI: 10.1093/Neuonc/Now212.375 |
0.392 |
|
| 2016 |
Sprague L, Currier M, Rizvi T, Nartker B, Chen C, Wang P, Hutzen B, Franczek M, Ecsedy J, Conner J, Ratner N, Cripe T. 666. Oncolytic Herpes Virotherapy Induces a Paracrine Death Signal Causing Synergistic Antitumor Efficacy with Aurora A Kinase Inhibition Molecular Therapy. 24: S263-S264. DOI: 10.1016/S1525-0016(16)33474-8 |
0.457 |
|
| 2015 |
Eiymo Mwa Mpollo MS, Brandt EB, Shanmukhappa SK, Arumugam PI, Tiwari S, Loberg A, Pillis D, Rizvi T, Lindsey M, Jonck B, Carmeliet P, Kalra VK, Le Cras TD, Ratner N, Wills-Karp M, et al. Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. The Journal of Clinical Investigation. PMID 26690703 DOI: 10.1172/Jci77250 |
0.31 |
|
| 2015 |
Patel AV, Johansson G, Colbert MC, Dasgupta B, Ratner N. Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors. Neuro-Oncology. PMID 26116612 DOI: 10.1093/neuonc/nov076 |
0.437 |
|
| 2015 |
Jousma E, Rizvi TA, Wu J, Janhofer D, Dombi E, Dunn RS, Kim MO, Masters AR, Jones DR, Cripe TP, Ratner N. Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1. Pediatric Blood & Cancer. PMID 25907661 DOI: 10.1002/pbc.25546 |
0.479 |
|
| 2015 |
Ratner N, Miller SJ. A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor. Nature Reviews. Cancer. 15: 290-301. PMID 25877329 DOI: 10.1038/nrc3911 |
0.444 |
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| 2015 |
Rauen KA, Huson SM, Burkitt-Wright E, Evans DG, Farschtschi S, Ferner RE, Gutmann DH, Hanemann CO, Kerr B, Legius E, Parada LF, Patton M, Peltonen J, Ratner N, Riccardi VM, et al. Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues. American Journal of Medical Genetics. Part A. 167: 1-10. PMID 25393061 DOI: 10.1002/Ajmg.A.36793 |
0.38 |
|
| 2015 |
Eiymo Mwa Mpollo M, Brandt E, Shanmukhappa SK, Arumugam P, Tiwari S, Loberg A, Rizvi T, Lindsey M, Jonckx B, Carmeliet P, Kalra V, Lecras T, Ratner N, wills-Karp M, Khurana hershey G, et al. Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness Blood. 126: 977-977. DOI: 10.1182/Blood.V126.23.977.977 |
0.316 |
|
| 2015 |
Currier M, Rizvi T, Nartker B, Chen D, Wang P, Patel A, Chaney K, Streby K, Kaur B, Grandi P, Glorioso J, Antonio Chiocca E, Ecsedy J, Conner J, Ratner N, et al. 432. Aurora A Kinase Inhibition Enhances Oncolytic Herpes Simplex Virotherapy in Models of Neuroblastoma Molecular Therapy. 23: S171. DOI: 10.1016/S1525-0016(16)34041-2 |
0.317 |
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| 2014 |
Lee MP, Ratner N, Yutzey KE. Genome-wide Twist1 occupancy in endocardial cushion cells, embryonic limb buds, and peripheral nerve sheath tumor cells. Bmc Genomics. 15: 821. PMID 25262113 DOI: 10.1186/1471-2164-15-821 |
0.422 |
|
| 2014 |
Pooya S, Liu X, Kumar VB, Anderson J, Imai F, Zhang W, Ciraolo G, Ratner N, Setchell KD, Yoshida Y, Yutaka Y, Jankowski MP, Dasgupta B. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nature Communications. 5: 4993. PMID 25256100 DOI: 10.1038/Ncomms5993 |
0.32 |
|
| 2014 |
Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis. The American Journal of Pathology. 184: 2082-98. PMID 24832557 DOI: 10.1016/J.Ajpath.2014.04.006 |
0.517 |
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| 2014 |
Watson AL, Anderson LK, Greeley AD, Keng VW, Rahrmann EP, Halfond AL, Powell NM, Collins MH, Rizvi T, Moertel CL, Ratner N, Largaespada DA. Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity. Oncotarget. 5: 1502-14. PMID 24681606 DOI: 10.18632/Oncotarget.1609 |
0.489 |
|
| 2014 |
Ehrman LA, Nardini D, Ehrman S, Rizvi TA, Gulick J, Krenz M, Dasgupta B, Robbins J, Ratner N, Nakafuku M, Waclaw RR. The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3767-78. PMID 24599474 DOI: 10.1523/Jneurosci.3515-13.2014 |
0.38 |
|
| 2014 |
Brundage ME, Tandon P, Eaves DW, Williams JP, Miller SJ, Hennigan RH, Jegga A, Cripe TP, Ratner N. MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1. Oncogene. 33: 5626-36. PMID 24509877 DOI: 10.1038/Onc.2013.506 |
0.803 |
|
| 2014 |
Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, ... ... Ratner N, et al. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. American Journal of Medical Genetics. Part A. 164: 563-78. PMID 24443315 DOI: 10.1002/Ajmg.A.36312 |
0.468 |
|
| 2014 |
Wu J, Patmore DM, Jousma E, Eaves DW, Breving K, Patel AV, Schwartz EB, Fuchs JR, Cripe TP, Stemmer-Rachamimov AO, Ratner N. EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors. Oncogene. 33: 173-80. PMID 23318430 DOI: 10.1038/Onc.2012.579 |
0.818 |
|
| 2014 |
Ratner N. Abstract IA10: Signaling through individual Ras proteins in the absence of the Nf1-RASGAP Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-Ia10 |
0.554 |
|
| 2014 |
Wu J, Jousma E, Rizvi T, Dunn RS, Jones DR, Cripe TP, Kim M, Marcus L, Dombi E, Baldwin A, Long LM, Andrea G, Whitcomb P, Peron SM, Widemann B, ... ... Ratner N, et al. Abstract A2: Using plexiform neurofibroma preclinical therapeutics to help guide clinical trials Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-A2 |
0.373 |
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| 2014 |
Wu J, Ratner N. Abstract 1404: An EGFR-Stat3-IL6 pathway contributes to NF1 tumor initiation and maintenance Cancer Research. 74: 1404-1404. DOI: 10.1158/1538-7445.Am2014-1404 |
0.527 |
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| 2014 |
Ratner N, Keng V, Patmore DM, Kendall JK, Jousma E, Choi K, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim M, Dombi E, Levy DE, Cancelas JA, Stemmer-Rachamimov A, et al. PM-18 * EGFR-STAT3 ACTIVATES -CATENIN SIGNALING TO DRIVE NEUROFIBROMA INITIATION IN NF1, AND PLAYS A ROLE IN TUMOR MAINTENANCE Neuro-Oncology. 16: v172-v173. DOI: 10.1093/Neuonc/Nou268.18 |
0.828 |
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| 2014 |
Titus-Mitchell H, Rizvi TA, Mayes DA, Miller SJ, Ratner N. Ras signaling and NO in oligodendrocytes modulate permeability of the blood–brain barrier Nitric Oxide. 42: 105. DOI: 10.1016/J.NIOX.2014.09.022 |
0.335 |
|
| 2013 |
Guo L, Lee AA, Rizvi TA, Ratner N, Kirschner LS. The protein kinase A regulatory subunit R1A (Prkar1a) plays critical roles in peripheral nerve development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17967-75. PMID 24227708 DOI: 10.1523/JNEUROSCI.0766-13.2013 |
0.458 |
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| 2013 |
Mayes DA, Rizvi TA, Titus-Mitchell H, Oberst R, Ciraolo GM, Vorhees CV, Robinson AP, Miller SD, Cancelas JA, Stemmer-Rachamimov AO, Ratner N. Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature. Cell Reports. 4: 1197-212. PMID 24035394 DOI: 10.1016/J.Celrep.2013.08.011 |
0.41 |
|
| 2013 |
Guo L, Moon C, Zheng Y, Ratner N. Cdc42 regulates Schwann cell radial sorting and myelin sheath folding through NF2/merlin-dependent and independent signaling. Glia. 61: 1906-21. PMID 24014231 DOI: 10.1002/glia.22567 |
0.488 |
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| 2013 |
Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nature Genetics. 45: 756-66. PMID 23685747 DOI: 10.1038/Ng.2641 |
0.496 |
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| 2013 |
Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, ... ... Ratner N, et al. Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance. Cancer Discovery. 3: 674-89. PMID 23535903 DOI: 10.1158/2159-8290.Cd-13-0081 |
0.527 |
|
| 2013 |
Largaespada D, Ratner N. Interweaving the strands: β-catenin, an HIV co-receptor, and Schwann cell tumors. Cancer Cell. 23: 269-71. PMID 23518344 DOI: 10.1016/J.Ccr.2013.03.001 |
0.439 |
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| 2013 |
Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, et al. Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria. American Journal of Medical Genetics. Part A. 161: 405-16. PMID 23401320 DOI: 10.1002/Ajmg.A.35760 |
0.412 |
|
| 2013 |
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, ... ... Ratner N, et al. MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. The Journal of Clinical Investigation. 123: 340-7. PMID 23221341 DOI: 10.1172/Jci60578 |
0.794 |
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| 2013 |
Prada CE, Jousma E, Rizvi TA, Wu J, Dunn RS, Mayes DA, Cancelas JA, Dombi E, Kim MO, West BL, Bollag G, Ratner N. Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition. Acta Neuropathologica. 125: 159-68. PMID 23099891 DOI: 10.1007/S00401-012-1056-7 |
0.491 |
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| 2013 |
Hennigan RF, Moon CA, Parysek LM, Monk KR, Morfini G, Berth S, Brady S, Ratner N. The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway. Oncogene. 32: 1135-43. PMID 22525268 DOI: 10.1038/Onc.2012.135 |
0.698 |
|
| 2013 |
Roy S, Konstantinidis DG, Rizvi T, Chang K, Sundaram N, Wourms M, Anastacia L, Song L, Burke K, Inagami T, Ratner N, Witte D, Kalfa TA, Cancelas JA, Shanmukhappa SK, et al. Increased Oxidative Stress In Sickle Cell Disease Activates The Renin-Angiotensin-TGF-β Pathway To Mediate Sickle Nephropathy Blood. 122: 2211-2211. DOI: 10.1182/Blood.V122.21.2211.2211 |
0.354 |
|
| 2013 |
Yang M, Loberg A, Rizvi T, Wourms M, Song L, Burke K, Ratner N, Carmeliet P, LeCras T, Wills-Karp M, Malik P. Airway Hyper-Responsiveness Associated With Sickle Cell Disease Is Mediated By Placenta Growth Factor Blood. 122: 185-185. DOI: 10.1182/Blood.V122.21.185.185 |
0.318 |
|
| 2013 |
Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Abstract 354: Conditional inactivation of Pten and overexpression of EGFR in Schwann cells results in early high-grade peripheral nerve sheath tumor development. Cancer Research. 73: 354-354. DOI: 10.1158/1538-7445.Am2013-354 |
0.53 |
|
| 2012 |
Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST. Sarcoma. 2012: 620834. PMID 23319880 DOI: 10.1155/2012/620834 |
0.525 |
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| 2012 |
Guo L, Moon C, Niehaus K, Zheng Y, Ratner N. Rac1 controls Schwann cell myelination through cAMP and NF2/merlin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17251-61. PMID 23197717 DOI: 10.1523/JNEUROSCI.2461-12.2012 |
0.411 |
|
| 2012 |
Gutmann DH, Parada LF, Silva AJ, Ratner N. Neurofibromatosis type 1: modeling CNS dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14087-93. PMID 23055477 DOI: 10.1523/Jneurosci.3242-12.2012 |
0.435 |
|
| 2012 |
Patmore DM, Welch S, Fulkerson PC, Wu J, Choi K, Eaves D, Kordich JJ, Collins MH, Cripe TP, Ratner N. In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1. Cancer Research. 72: 5317-27. PMID 22918885 DOI: 10.1158/0008-5472.Can-12-1972 |
0.837 |
|
| 2012 |
Acosta MT, Bearden CE, Castellanos FX, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, et al. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American Journal of Medical Genetics. Part A. 158: 2225-32. PMID 22821737 DOI: 10.1002/Ajmg.A.35535 |
0.311 |
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| 2012 |
Patel AV, Eaves D, Jessen WJ, Rizvi TA, Ecsedy JA, Qian MG, Aronow BJ, Perentesis JP, Serra E, Cripe TP, Miller SJ, Ratner N. Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5020-30. PMID 22811580 DOI: 10.1158/1078-0432.Ccr-12-1072 |
0.558 |
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| 2012 |
Keng VW, Rahrmann EP, Watson AL, Tschida BR, Moertel CL, Jessen WJ, Rizvi TA, Collins MH, Ratner N, Largaespada DA. PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors. Cancer Research. 72: 3405-13. PMID 22700876 DOI: 10.1158/0008-5472.Can-11-4092 |
0.586 |
|
| 2012 |
Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, ... ... Ratner N, et al. Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathologica. 123: 369-80. PMID 22083253 DOI: 10.1007/S00401-011-0905-0 |
0.442 |
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| 2012 |
Wu J, Dombi E, Jousma E, Scott Dunn R, Lindquist D, Schnell BM, Kim MO, Kim A, Widemann BC, Cripe TP, Ratner N. Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging. Pediatric Blood & Cancer. 58: 173-80. PMID 21319287 DOI: 10.1002/pbc.23015 |
0.449 |
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| 2012 |
Patel A, Ratner N. Abstract 877: Identification of novel genes critical to survival of MPNST cells via medium throughput screening using lentiviral shRNA Cancer Research. 72: 877-877. DOI: 10.1158/1538-7445.Am2012-877 |
0.477 |
|
| 2012 |
Wu J, Keng V, Patmore DM, Jousma E, Eaves DW, Johansson G, Schwartz EB, Fuchs JR, Dunn S, Lindquist D, Dombi E, Widemann BC, Stemmer-Rachamimov Ao, Cancelas JA, Cripe TP, ... ... Ratner N, et al. Abstract 2937: An EGFR-STAT3 pathway promotes NF1 peripheral nerve tumorigenesis and transformation Cancer Research. 72: 2937-2937. DOI: 10.1158/1538-7445.Am2012-2937 |
0.831 |
|
| 2012 |
Patmore DM, Welch S, Fulkerson P, Wu J, Choi K, Eaves D, Kordich J, Collins MH, Cripe TP, Ratner N. Abstract 1433: TC21/R-Ras2 is a critical mediator of the Nf1 oncogenic switch Cancer Research. 72: 1433-1433. DOI: 10.1158/1538-7445.Am2012-1433 |
0.83 |
|
| 2012 |
Meany H, Widemann BC, Ratner N. Malignant peripheral nerve sheath tumors: Prognostic and diagnostic markers and therapeutic targets Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 445-467. DOI: 10.1007/978-3-642-32864-0_29 |
0.303 |
|
| 2011 |
Yang J, Ylipää A, Sun Y, Zheng H, Chen K, Nykter M, Trent J, Ratner N, Lev DC, Zhang W. Genomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7563-73. PMID 22042973 DOI: 10.1158/1078-0432.Ccr-11-1707 |
0.495 |
|
| 2011 |
Wood M, Rawe M, Johansson G, Pang S, Soderquist RS, Patel AV, Nelson S, Seibel W, Ratner N, Sanchez Y. Discovery of a small molecule targeting IRA2 deletion in budding yeast and neurofibromin loss in malignant peripheral nerve sheath tumor cells. Molecular Cancer Therapeutics. 10: 1740-50. PMID 21697395 DOI: 10.1158/1535-7163.Mct-11-0309 |
0.543 |
|
| 2011 |
Shang X, Cancelas JA, Li L, Guo F, Liu W, Johnson JF, Ficker A, Daria D, Geiger H, Ratner N, Zheng Y. R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization. The Journal of Biological Chemistry. 286: 24068-78. PMID 21572048 DOI: 10.1074/jbc.M111.226951 |
0.385 |
|
| 2011 |
Mayes DA, Rizvi TA, Cancelas JA, Kolasinski NT, Ciraolo GM, Stemmer-Rachamimov AO, Ratner N. Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation. Cancer Research. 71: 4675-85. PMID 21551249 DOI: 10.1158/0008-5472.Can-10-4558 |
0.569 |
|
| 2010 |
Ryan MA, Nattamai KJ, Xing E, Schleimer D, Daria D, Sengupta A, Köhler A, Liu W, Gunzer M, Jansen M, Ratner N, Le Cras TD, Waterstrat A, Van Zant G, Cancelas JA, et al. Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization. Nature Medicine. 16: 1141-6. PMID 20871610 DOI: 10.1038/nm.2217 |
0.342 |
|
| 2010 |
Hummel TR, Jessen WJ, Miller SJ, Kluwe L, Mautner VF, Wallace MR, Lázaro C, Page GP, Worley PF, Aronow BJ, Schorry EK, Ratner N. Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5048-57. PMID 20739432 DOI: 10.1158/1078-0432.Ccr-10-0613 |
0.49 |
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| 2010 |
Bosco EE, Nakai Y, Hennigan RF, Ratner N, Zheng Y. NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation. Oncogene. 29: 2540-9. PMID 20154721 DOI: 10.1038/onc.2010.20 |
0.545 |
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| 2010 |
Kissil JL, Blakeley JO, Ferner RE, Huson SM, Kalamarides M, Mautner VF, McCormick F, Morrison H, Packer R, Ramesh V, Ratner N, Rauen KA, Stevenson DA, Hunter-Schaedle K, North K. What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: new frontiers. American Journal of Medical Genetics. Part A. 152: 269-83. PMID 20082461 DOI: 10.1002/Ajmg.A.33189 |
0.333 |
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| 2010 |
Miller SJ, Lan ZD, Hardiman A, Wu J, Kordich JJ, Patmore DM, Hegde RS, Cripe TP, Cancelas JA, Collins MH, Ratner N. Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis. Oncogene. 29: 368-79. PMID 19901965 DOI: 10.1038/Onc.2009.360 |
0.834 |
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| 2010 |
Largaespada DA, Rahrmann EP, Keng VW, Clark HB, Dupuy AJ, Tessarollo L, Jenkins NA, Copeland NG, Ratner N. Abstract 2199: A murine insertional mutagenesis screen to identify oncogenes and tumor suppressor genes involved in Schwann cell tumorigenesis Cancer Research. 70: 2199-2199. DOI: 10.1158/1538-7445.Am10-2199 |
0.537 |
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| 2009 |
Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, ... ... Ratner N, et al. Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. Embo Molecular Medicine. 1: 236-48. PMID 20049725 DOI: 10.1002/Emmm.200900027 |
0.487 |
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| 2009 |
Mahller YY, Williams JP, Baird WH, Mitton B, Grossheim J, Saeki Y, Cancelas JA, Ratner N, Cripe TP. Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus. Plos One. 4: e4235. PMID 19156211 DOI: 10.1371/journal.pone.0004235 |
0.441 |
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| 2008 |
Williams JP, Wu J, Johansson G, Rizvi TA, Miller SC, Geiger H, Malik P, Li W, Mukouyama YS, Cancelas JA, Ratner N. Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential. Cell Stem Cell. 3: 658-69. PMID 19041782 DOI: 10.1016/J.Stem.2008.10.003 |
0.517 |
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| 2008 |
Carroll SL, Ratner N. How does the Schwann cell lineage form tumors in NF1? Glia. 56: 1590-605. PMID 18803326 DOI: 10.1002/glia.20776 |
0.574 |
|
| 2008 |
Johansson G, Mahller YY, Collins MH, Kim MO, Nobukuni T, Perentesis J, Cripe TP, Lane HA, Kozma SC, Thomas G, Ratner N. Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Molecular Cancer Therapeutics. 7: 1237-45. PMID 18483311 DOI: 10.1158/1535-7163.Mct-07-2335 |
0.505 |
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| 2008 |
Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell. 13: 105-16. PMID 18242511 DOI: 10.1016/J.Ccr.2007.12.027 |
0.559 |
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| 2008 |
Ratner N, Miller SJ, Ling B, Huang YN, Bennett MR, Mckinnon R, Rizvi TA. CNS glial progenitors and schwann cells in neurofibromatosis Type 1 Journal of Neurochemistry. 81: 2-2. DOI: 10.1046/J.1471-4159.81.S1.48_2.X |
0.557 |
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| 2007 |
Monk KR, Wu J, Williams JP, Finney BA, Fitzgerald ME, Filippi MD, Ratner N. Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve. Neuron Glia Biology. 3: 233-44. PMID 18634614 DOI: 10.1017/S1740925X08000021 |
0.663 |
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| 2007 |
Mahller YY, Vaikunth SS, Currier MA, Miller SJ, Ripberger MC, Hsu YH, Mehrian-Shai R, Collins MH, Crombleholme TM, Ratner N, Cripe TP. Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 279-86. PMID 17235305 DOI: 10.1038/sj.mt.6300038 |
0.514 |
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| 2007 |
Shang X, Li L, Concelas J, Guo F, Daria D, Geiger H, Ratner N, Zheng Y. R-Ras Regulates Hematopoietic Stem/Progenitor Cell Adhesion, Migration, and Mobilization through Rac GTPase-Mediated Signals. Blood. 110: 221-221. DOI: 10.1182/BLOOD.V110.11.221.221 |
0.406 |
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| 2007 |
Ryan MA, Schleimer D, Nattamai K, Daria D, Le Cras T, Ratner N, Geiger H. Positional Cloning: Regulation of Hematopoietic Stem and Progenitor Cell Mobilization through EGF Receptor Signaling. Blood. 110: 1252-1252. DOI: 10.1182/BLOOD.V110.11.1252.1252 |
0.317 |
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| 2006 |
Albritton KH, Rankin C, Coffin CM, Ratner N, Budd GT, Schuetze SM, Randall RL, Declue JE, Borden EC. Phase II study of erlotinib in metastatic or unresectable malignant peripheral nerve sheath tumors (MPNST). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 9518. PMID 27952832 DOI: 10.1200/jco.2006.24.18_suppl.9518 |
0.332 |
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| 2006 |
Ratner N, Williams JP, Kordich JJ, Kim HA. Schwann cell preparation from single mouse embryos: analyses of neurofibromin function in Schwann cells. Methods in Enzymology. 407: 22-33. PMID 16757311 DOI: 10.1016/S0076-6879(05)07003-5 |
0.474 |
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| 2006 |
Wu J, Crimmins JT, Monk KR, Williams JP, Fitzgerald ME, Tedesco S, Ratner N. Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibroma. The American Journal of Pathology. 168: 1686-96. PMID 16651634 DOI: 10.2353/Ajpath.2006.050859 |
0.695 |
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| 2006 |
Nakai Y, Zheng Y, MacCollin M, Ratner N. Temporal control of Rac in Schwann cell-axon interaction is disrupted in NF2-mutant schwannoma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3390-5. PMID 16571745 DOI: 10.1523/JNEUROSCI.4865-05.2006 |
0.461 |
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| 2006 |
Miller SJ, Rangwala F, Williams J, Ackerman P, Kong S, Jegga AG, Kaiser S, Aronow BJ, Frahm S, Kluwe L, Mautner V, Upadhyaya M, Muir D, Wallace M, Hagen J, ... ... Ratner N, et al. Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Research. 66: 2584-91. PMID 16510576 DOI: 10.1158/0008-5472.Can-05-3330 |
0.785 |
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| 2006 |
Mahller YY, Rangwala F, Ratner N, Cripe TP. Malignant peripheral nerve sheath tumors with high and low Ras-GTP are permissive for oncolytic herpes simplex virus mutants. Pediatric Blood & Cancer. 46: 745-54. PMID 16124003 DOI: 10.1002/Pbc.20565 |
0.78 |
|
| 2006 |
Mahller YY, Currier MA, Collins MH, Ratner N, Cripe TP. 658. Oncolytic Herpes Virus Mutants Are Efficacious Against Malignant Peripheral Nerve Sheath Tumor Xenografts Molecular Therapy. 13: S253-S254. DOI: 10.1016/J.YMTHE.2006.08.734 |
0.482 |
|
| 2006 |
Williams J, Wu J, Colbert M, Cancelas J, Ratner N. [P80]: An amplified EGF‐dependent peripheral nervous system progenitor in neurofibromatosis type 1 International Journal of Developmental Neuroscience. 24: 530-530. DOI: 10.1016/j.ijdevneu.2006.09.142 |
0.308 |
|
| 2006 |
Ratner N, Williams J, Wu J, Kordich J, Miller S, Colbert M, Cancelas J. [S39]: EGFR signalling identifies an embryonic peripheral nerve progenitor cell amplified by mutation in the
Nf1
gene International Journal of Developmental Neuroscience. 24: 488-489. DOI: 10.1016/j.ijdevneu.2006.09.046 |
0.457 |
|
| 2006 |
Ratner N, Miller SJ. Model systems for neurofibroma and malignant peripheral nerve sheath tumor Drug Discovery Today: Disease Models. 3: 175-182. DOI: 10.1016/j.ddmod.2006.06.001 |
0.477 |
|
| 2005 |
Aguirre A, Rizvi TA, Ratner N, Gallo V. Overexpression of the epidermal growth factor receptor confers migratory properties to nonmigratory postnatal neural progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11092-106. PMID 16319309 DOI: 10.1523/JNEUROSCI.2981-05.2005 |
0.373 |
|
| 2005 |
Ling BC, Wu J, Miller SJ, Monk KR, Shamekh R, Rizvi TA, Decourten-Myers G, Vogel KS, DeClue JE, Ratner N. Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis. Cancer Cell. 7: 65-75. PMID 15652750 DOI: 10.1016/J.Ccr.2004.10.016 |
0.722 |
|
| 2004 |
Tang Y, Lu A, Ran R, Aronow BJ, Schorry EK, Hopkin RJ, Gilbert DL, Glauser TA, Hershey AD, Richtand NW, Privitera M, Dalvi A, Sahay A, Szaflarski JP, Ficker DM, ... Ratner N, et al. Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1. Brain Research. Molecular Brain Research. 132: 155-67. PMID 15582155 DOI: 10.1016/j.molbrainres.2003.10.014 |
0.371 |
|
| 2004 |
Corfas G, Velardez MO, Ko CP, Ratner N, Peles E. Mechanisms and roles of axon-Schwann cell interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9250-60. PMID 15496660 DOI: 10.1523/Jneurosci.3649-04.2004 |
0.333 |
|
| 2004 |
Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, ... ... Ratner N, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.Can-03-4079 |
0.452 |
|
| 2004 |
Stickney JT, Bacon WC, Rojas M, Ratner N, Ip W. Activation of the tumor suppressor merlin modulates its interaction with lipid rafts. Cancer Research. 64: 2717-24. PMID 15087385 DOI: 10.1158/0008-5472.Can-03-3798 |
0.428 |
|
| 2004 |
Huang Y, Rangwala F, Fulkerson PC, Ling B, Reed E, Cox AD, Kamholz J, Ratner N. Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells. Oncogene. 23: 368-78. PMID 14724565 DOI: 10.1038/Sj.Onc.1207075 |
0.754 |
|
| 2003 |
Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. The Journal of Clinical Investigation. 112: 1851-61. PMID 14679180 DOI: 10.1172/Jci19195 |
0.73 |
|
| 2003 |
Bennett MR, Rizvi TA, Karyala S, McKinnon RD, Ratner N. Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7207-17. PMID 12904481 DOI: 10.1523/Jneurosci.23-18-07207.2003 |
0.47 |
|
| 2003 |
Miller SJ, Li H, Rizvi TA, Huang Y, Johansson G, Bowersock J, Sidani A, Vitullo J, Vogel K, Parysek LM, DeClue JE, Ratner N. Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesis. Molecular and Cellular Biology. 23: 2213-24. PMID 12612091 DOI: 10.1128/MCB.23.6.2213-2224.2003 |
0.556 |
|
| 2003 |
Manent J, Oguievetskaia K, Bayer J, Ratner N, Giovannini M. Magnetic cell sorting for enriching Schwann cells from adult mouse peripheral nerves. Journal of Neuroscience Methods. 123: 167-73. PMID 12606065 DOI: 10.1016/S0165-0270(02)00349-7 |
0.435 |
|
| 2002 |
Rizvi TA, Huang Y, Sidani A, Atit R, Largaespada DA, Boissy RE, Ratner N. A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9831-40. PMID 12427839 DOI: 10.1523/Jneurosci.22-22-09831.2002 |
0.474 |
|
| 2002 |
Xu Y, Chiamvimonvat N, Vázquez AE, Akunuru S, Ratner N, Yamoah EN. Gene-targeted deletion of neurofibromin enhances the expression of a transient outward K+ current in Schwann cells: a protein kinase A-mediated mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9194-202. PMID 12417644 DOI: 10.1523/Jneurosci.22-21-09194.2002 |
0.478 |
|
| 2002 |
Bashour AM, Meng JJ, Ip W, MacCollin M, Ratner N. The neurofibromatosis type 2 gene product, merlin, reverses the F-actin cytoskeletal defects in primary human Schwannoma cells. Molecular and Cellular Biology. 22: 1150-7. PMID 11809806 DOI: 10.1128/Mcb.22.4.1150-1157.2002 |
0.523 |
|
| 2001 |
Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI. The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling. Developmental Cell. 1: 63-72. PMID 11703924 DOI: 10.1016/S1534-5807(01)00009-0 |
0.557 |
|
| 2001 |
Steigerwald K, Santoro IM, Kordich JJ, Gismondi V, Trzepacz C, Badiali M, Giangaspero F, Balko MG, Graham JS, Ratner N, Lowy AM, Varesco L, Groden J. A distinct splice form of APC is highly expressed in neurones but not commonly mutated in neuroepithelial tumours. Journal of Medical Genetics. 38: 257-62. PMID 11370631 DOI: 10.1136/Jmg.38.4.257 |
0.357 |
|
| 2001 |
Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A. The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. Oncogene. 20: 97-105. PMID 11244508 DOI: 10.1038/sj.onc.1204026 |
0.563 |
|
| 2001 |
Kim HA, Ratner N, Roberts TM, Stiles CD. Schwann cell proliferative responses to cAMP and Nf1 are mediated by cyclin D1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1110-6. PMID 11160381 DOI: 10.1523/Jneurosci.21-04-01110.2001 |
0.459 |
|
| 2001 |
Ratner N, Miller S, DeClue J. Gene expression analysis of NF1 mutant Schwann cells Nature Genetics. 27: 81-81. DOI: 10.1038/87262 |
0.43 |
|
| 2000 |
Meng JJ, Lowrie DJ, Sun H, Dorsey E, Pelton PD, Bashour AM, Groden J, Ratner N, Ip W. Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin. Journal of Neuroscience Research. 62: 491-502. PMID 11070492 DOI: 10.1002/1097-4547(20001115)62:4<491::Aid-Jnr3>3.0.Co;2-D |
0.387 |
|
| 2000 |
Sherman LS, Rizvi TA, Karyala S, Ratner N. CD44 enhances neuregulin signaling by Schwann cells. The Journal of Cell Biology. 150: 1071-84. PMID 10973996 DOI: 10.1083/Jcb.150.5.1071 |
0.352 |
|
| 2000 |
Sherman LS, Atit R, Rosenbaum T, Cox AD, Ratner N. Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. The Journal of Biological Chemistry. 275: 30740-5. PMID 10900196 DOI: 10.1074/Jbc.M001702200 |
0.477 |
|
| 2000 |
Atit RP, Mitchell K, Nguyen L, Warshawsky D, Ratner N. The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice. The Journal of Investigative Dermatology. 114: 1093-100. PMID 10844550 DOI: 10.1046/j.1523-1747.2000.00994.x |
0.473 |
|
| 2000 |
DeClue JE, Heffelfinger S, Benvenuto G, Ling B, Li S, Rui W, Vass WC, Viskochil D, Ratner N. Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models. The Journal of Clinical Investigation. 105: 1233-41. PMID 10791998 DOI: 10.1172/JCI7610 |
0.529 |
|
| 1999 |
Rosenbaum T, Kim HA, Boissy YL, Ling BO, Ratner N. Neurofibromin, the Neurofibromatosis Type 1 Ras-GAP, Is Required for Appropriate P0 Expression and Myelination. Annals of the New York Academy of Sciences. 883: 203-214. PMID 29086925 DOI: 10.1111/J.1749-6632.1999.Tb08583.X |
0.503 |
|
| 1999 |
Sherman L, Sleeman JP, Hennigan RF, Herrlich P, Ratner N. Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro. Oncogene. 18: 6692-9. PMID 10597275 DOI: 10.1038/Sj.Onc.1203055 |
0.475 |
|
| 1999 |
Rosenbaum T, Kim HA, Boissy YL, Ling B, Ratner N. Neurofibromin, the neurofibromatosis type 1 Ras-GAP, is required for appropriate P0 expression and myelination. Annals of the New York Academy of Sciences. 883: 203-14. PMID 10586246 |
0.407 |
|
| 1999 |
Atit RP, Crowe MJ, Greenhalgh DG, Wenstrup RJ, Ratner N. The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts. The Journal of Investigative Dermatology. 112: 835-42. PMID 10383727 DOI: 10.1046/j.1523-1747.1999.00609.x |
0.474 |
|
| 1999 |
Rizvi TA, Akunuru S, de Courten-Myers G, Switzer RC, Nordlund ML, Ratner N. Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor. Brain Research. 816: 111-23. PMID 9878702 DOI: 10.1016/S0006-8993(98)01133-0 |
0.378 |
|
| 1998 |
Pelton PD, Sherman LS, Rizvi TA, Marchionni MA, Wood P, Friedman RA, Ratner N. Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells. Oncogene. 17: 2195-209. PMID 9811451 DOI: 10.1038/Sj.Onc.1202141 |
0.513 |
|
| 1998 |
Ratner N, Bloom GS, Brady ST. A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7717-26. PMID 9742142 DOI: 10.1523/Jneurosci.18-19-07717.1998 |
0.317 |
|
| 1997 |
Rosenbaum C, Karyala S, Marchionni MA, Kim HA, Krasnoselsky AL, Happel B, Isaacs I, Brackenbury R, Ratner N. Schwann cells express NDF and SMDF/n-ARIA mRNAs, secrete neuregulin, and show constitutive activation of erbB3 receptors: evidence for a neuregulin autocrine loop. Experimental Neurology. 148: 604-15. PMID 9417836 DOI: 10.1006/Exnr.1997.6696 |
0.432 |
|
| 1997 |
Kim HA, DeClue JE, Ratner N. cAMP-dependent protein kinase A is required for Schwann cell growth: interactions between the cAMP and neuregulin/tyrosine kinase pathways. Journal of Neuroscience Research. 49: 236-47. PMID 9272646 DOI: 10.1002/(Sici)1097-4547(19970715)49:2<236::Aid-Jnr12>3.0.Co;2-Z |
0.373 |
|
| 1997 |
Kim HA, Ling B, Ratner N. Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase. Molecular and Cellular Biology. 17: 862-72. PMID 9001241 DOI: 10.1128/Mcb.17.2.862 |
0.533 |
|
| 1997 |
Rosenbaum T, Patrie KM, Ratner N. Neurofibromatosis type 1: Genetic and cellular mechanisms of peripheral nerve tumor formation Neuroscientist. 3: 712-720. DOI: 10.1177/107385849700300614 |
0.564 |
|
| 1995 |
Wrabetz L, Feltri ML, Kim H, Daston M, Kamholz J, Scherer SS, Ratner N. Regulation of neurofibromin expression in rat sciatic nerve and cultured Schwann cells. Glia. 15: 22-32. PMID 8847098 DOI: 10.1002/Glia.440150104 |
0.497 |
|
| 1995 |
Rosenbaum T, Boissy YL, Kombrinck K, Brannan CI, Jenkins NA, Copeland NG, Ratner N. Neurofibromin-deficient fibroblasts fail to form perineurium in vitro. Development (Cambridge, England). 121: 3583-92. PMID 8582272 |
0.34 |
|
| 1995 |
Kim HA, Rosenbaum T, Marchionni MA, Ratner N, DeClue JE. Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes. Oncogene. 11: 325-35. PMID 7624147 |
0.447 |
|
| 1995 |
Nordlund ML, Rizvi TA, Brannan CI, Ratner N. Neurofibromin expression and astrogliosis in neurofibromatosis (type 1) brains. Journal of Neuropathology and Experimental Neurology. 54: 588-600. PMID 7602332 DOI: 10.1097/00005072-199507000-00013 |
0.383 |
|
| 1994 |
Malhotra R, Ratner N. Localization of neurofibromin to keratinocytes and melanocytes in developing rat and human skin. The Journal of Investigative Dermatology. 102: 812-8. PMID 8176268 DOI: 10.1111/1523-1747.Ep12379925 |
0.313 |
|
| 1994 |
Krasnoselsky A, Massay MJ, DeFrances MC, Michalopoulos G, Zarnegar R, Ratner N. Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7284-90. PMID 7996175 DOI: 10.1523/Jneurosci.14-12-07284.1994 |
0.495 |
|
| 1994 |
Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes & Development. 8: 1019-29. PMID 7926784 DOI: 10.1101/Gad.8.9.1019 |
0.47 |
|
| 1993 |
Nordlund M, Gu X, Shipley MT, Ratner N. Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 1588-600. PMID 8463837 DOI: 10.1523/Jneurosci.13-04-01588.1993 |
0.392 |
|
| 1993 |
Bhattacharyya A, Brackenbury R, Ratner N. Neuron-Schwann cell signals are conserved across species: purification and characterization of embryonic chicken Schwann cells. Journal of Neuroscience Research. 35: 1-13. PMID 7685394 DOI: 10.1002/Jnr.490350102 |
0.375 |
|
| 1992 |
DeClue JE, Papageorge AG, Fletcher JA, Diehl SR, Ratner N, Vass WC, Lowy DR. Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell. 69: 265-73. PMID 1568246 DOI: 10.1016/0092-8674(92)90407-4 |
0.514 |
|
| 1992 |
Daston MM, Scrable H, Nordlund M, Sturbaum AK, Nissen LM, Ratner N. The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes. Neuron. 8: 415-28. PMID 1550670 DOI: 10.1016/0896-6273(92)90270-N |
0.447 |
|
| 1992 |
Nordlund M, Hong D, Fei X, Ratner N. Schwann cells and cells in the oligodendrocyte lineage proliferate in response to a 50,000 dalton membrane-associated mitogen present in developing brain. Glia. 5: 182-92. PMID 1534065 DOI: 10.1002/glia.440050304 |
0.378 |
|
| 1992 |
Daston MM, Ratner N. Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 195: 216-26. PMID 1301085 DOI: 10.1002/aja.1001950307 |
0.372 |
|
| 1992 |
Norgren RB, Ratner N, Brackenbury R. Development of olfactory nerve glia defined by a monoclonal antibody specific for Schwann cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 194: 231-8. PMID 1281697 DOI: 10.1002/aja.1001940308 |
0.338 |
|
| 1991 |
Daston MM, Ratner N. Expression of P30, a protein with adhesive properties, in Schwann cells and neurons of the developing and regenerating peripheral nerve. The Journal of Cell Biology. 112: 1229-39. PMID 1999471 DOI: 10.1083/Jcb.112.6.1229 |
0.386 |
|
| 1991 |
Bhattacharyya A, Frank E, Ratner N, Brackenbury R. P0 is an early marker of the Schwann cell lineage in chickens. Neuron. 7: 831-44. PMID 1720625 DOI: 10.1016/0896-6273(91)90285-8 |
0.33 |
|
| 1990 |
Ratner N, Lieberman MA, Riccardi VM, Hong DM. Mitogen accumulation in von Recklinghausen neurofibromatosis. Annals of Neurology. 27: 298-303. PMID 2109571 DOI: 10.1002/ana.410270312 |
0.494 |
|
| 1990 |
Sheela S, Riccardi VM, Ratner N. Angiogenic and invasive properties of neurofibroma Schwann cells. The Journal of Cell Biology. 111: 645-53. PMID 1696266 DOI: 10.1083/Jcb.111.2.645 |
0.515 |
|
| 1988 |
Ratner N, Hong DM, Lieberman MA, Bunge RP, Glaser L. The neuronal cell-surface molecule mitogenic for Schwann cells is a heparin-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 85: 6992-6. PMID 3413130 DOI: 10.1073/Pnas.85.18.6992 |
0.359 |
|
| 1986 |
Ratner N, Elbein A, Bunge MB, Porter S, Bunge RP, Glaser L. Specific asparagine-linked oligosaccharides are not required for certain neuron-neuron and neuron-Schwann cell interactions. The Journal of Cell Biology. 103: 159-70. PMID 3522602 DOI: 10.1083/jcb.103.1.159 |
0.324 |
|
| 1986 |
Ratner N, Bunge RP, Glaser L. Schwann cell proliferation in vitro. An overview. Annals of the New York Academy of Sciences. 486: 170-81. PMID 3471154 DOI: 10.1111/j.1749-6632.1986.tb48072.x |
0.4 |
|
| 1985 |
Ratner N, Bunge RP, Glaser L. A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation. The Journal of Cell Biology. 101: 744-54. PMID 3161898 DOI: 10.1083/Jcb.101.3.744 |
0.335 |
|
| 1984 |
Ratner N, Glaser L, Bunge RP. PC12 cells as a source of neurite-derived cell surface mitogen, which stimulates Schwann cell division. The Journal of Cell Biology. 98: 1150-5. PMID 6321518 DOI: 10.1083/Jcb.98.3.1150 |
0.368 |
|
| 1983 |
Ratner N, Mahler HR. Structural organization of filamentous proteins in postsynaptic density. Biochemistry. 22: 2446-53. PMID 6860641 DOI: 10.1021/Bi00279A022 |
0.419 |
|
| 1983 |
Ratner N, Mahler H. Isolation of postsynaptic densities retaining their membrane attachment. Neuroscience. 9: 631-44. PMID 6413886 DOI: 10.1016/0306-4522(83)90179-3 |
0.424 |
|
| 1982 |
Mahler HR, Kleine LP, Ratner N, Sorensen RG. Identification and topography of synaptic phosphoproteins. Progress in Brain Research. 56: 27-48. PMID 7163503 DOI: 10.1016/S0079-6123(08)63767-X |
0.441 |
|
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