Noboru Hiroi - Publications

Albert Einstein College of Medicine of Yeshiva University, NY, United States 
nicotine dependence, autism, mental retardation, schizophrenia

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hiramoto T, Sumiyoshi A, Yamauchi T, Tanigaki K, Shi Q, Kang G, Ryoke R, Nonaka H, Enomoto S, Izumi T, Bhat MA, Kawashima R, Hiroi N. Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice. Molecular Psychiatry. PMID 34737458 DOI: 10.1038/s41380-021-01318-4  0.524
2021 Nakamura M, Ye K, E Silva MB, Yamauchi T, Hoeppner DJ, Fayyazuddin A, Kang G, Yuda EA, Nagashima M, Enomoto S, Hiramoto T, Sharp R, Kaneko I, Tajinda K, Adachi M, ... ... Hiroi N, et al. Computational identification of variables in neonatal vocalizations predictive for postpubertal social behaviors in a mouse model of 16p11.2 deletion. Molecular Psychiatry. PMID 33859357 DOI: 10.1038/s41380-021-01089-y  0.574
2020 Kato R, Machida A, Nomoto K, Kang G, Hiramoto T, Tanigaki K, Mogi K, Hiroi N, Kikusui T. Maternal approach behaviors toward neonatal calls are impaired by mother's experiences of raising pups with a risk gene variant for autism. Developmental Psychobiology. PMID 32573780 DOI: 10.1002/Dev.22006  0.532
2019 Zinkstok JR, Boot E, Bassett AS, Hiroi N, Butcher NJ, Vingerhoets C, Vorstman JAS, van Amelsvoort TAMJ. Neurobiological perspective of 22q11.2 deletion syndrome. The Lancet. Psychiatry. PMID 31395526 DOI: 10.1016/S2215-0366(19)30076-8  0.338
2019 Hiroi N, Yamauchi T. Modeling and predicting developmental trajectories of neuropsychiatric dimensions associated with copy number variations. The International Journal of Neuropsychopharmacology. PMID 31135887 DOI: 10.1093/Ijnp/Pyz026  0.375
2018 Hiroi N. Critical Reappraisal of Mechanistic Links of Copy Number Variants to Dimensional Constructs of Neuropsychiatric Disorders in Mouse Models. Psychiatry and Clinical Neurosciences. PMID 29369447 DOI: 10.1111/Pcn.12641  0.352
2017 Boku S, Izumi T, Abe S, Takahashi T, Nishi A, Nomaru H, Naka Y, Kang G, Nagashima M, Hishimoto A, Enomoto S, Duran-Torres G, Tanigaki K, Zhang J, Ye K, ... ... Hiroi N, et al. Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis. Molecular Psychiatry. PMID 28827761 DOI: 10.1038/Mp.2017.158  0.348
2017 Solís O, García-Montes JR, Garcia-Sanz P, Herranz AS, Asensio MJ, Kang G, Hiroi N, Moratalla R. Human COMT over-expression confers a heightened susceptibility to dyskinesia in mice. Neurobiology of Disease. PMID 28315782 DOI: 10.1016/J.Nbd.2017.03.006  0.727
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Hiroi N, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/J.Biopsych.2016.05.004  0.706
2016 Hiroi N, Nishi A. Dimensional Deconstruction and Reconstruction of CNV-Associated Neuropsychiatric Disorders Handbook of Behavioral Neuroscience. 23: 285-302. DOI: 10.1016/B978-0-12-800981-9.00017-1  0.325
2015 Takahashi T, Okabe S, Broin PÓ, Nishi A, Ye K, Beckert MV, Izumi T, Machida A, Kang G, Abe S, Pena JL, Golden A, Kikusui T, Hiroi N. Structure and function of neonatal social communication in a genetic mouse model of autism. Molecular Psychiatry. PMID 26666205 DOI: 10.1038/Mp.2015.190  0.312
2014 Hiroi N. Small cracks in the dam: rare genetic variants provide opportunities to delve into mechanisms of neuropsychiatric disorders. Biological Psychiatry. 76: 91-2. PMID 24948383 DOI: 10.1016/J.Biopsych.2014.05.002  0.329
2013 Hiroi N, Takahashi T, Hishimoto A, Izumi T, Boku S, Hiramoto T. Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders. Molecular Psychiatry. 18: 1153-65. PMID 23917946 DOI: 10.1038/Mp.2013.92  0.552
2012 Hiroi N, Hiramoto T, Harper KM, Suzuki G, Boku S. Mouse Models of 22q11.2-Associated Autism Spectrum Disorder. Autism-Open Access. 001. PMID 25089229 DOI: 10.4172/2165-7890.S1-001  0.768
2012 Harper KM, Hiramoto T, Tanigaki K, Kang G, Suzuki G, Trimble W, Hiroi N. Alterations of social interaction through genetic and environmental manipulation of the 22q11.2 gene Sept5 in the mouse brain. Human Molecular Genetics. 21: 3489-99. PMID 22589251 DOI: 10.1093/Hmg/Dds180  0.785
2012 Yoshida A, Yamamoto N, Kinoshita M, Hiroi N, Hiramoto T, Kang G, Trimble WS, Tanigaki K, Nakagawa T, Ito J. Localization of septin proteins in the mouse cochlea. Hearing Research. 289: 40-51. PMID 22575789 DOI: 10.1016/J.Heares.2012.04.015  0.526
2012 Lapidus KA, Nwokafor C, Scott D, Baroni TE, Tenenbaum SA, Hiroi N, Singer RH, Czaplinski K. Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 35-42. PMID 22240322 DOI: 10.1101/Lm.024471.111  0.557
2011 Hiramoto T, Kang G, Suzuki G, Satoh Y, Kucherlapati R, Watanabe Y, Hiroi N. Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model. Human Molecular Genetics. 20: 4775-85. PMID 21908517 DOI: 10.1093/Hmg/Ddr404  0.749
2011 Scott D, Hiroi N. Deconstructing craving: dissociable cortical control of cue reactivity in nicotine addiction. Biological Psychiatry. 69: 1052-9. PMID 21429478 DOI: 10.1016/J.Biopsych.2011.01.023  0.476
2010 Scott D, Hiroi N. Emergence of dormant conditioned incentive approach by conditioned withdrawal in nicotine addiction. Biological Psychiatry. 68: 726-32. PMID 20598291 DOI: 10.1016/J.Biopsych.2010.05.017  0.502
2010 Agatsuma S, Dang MT, Li Y, Hiroi N. N-methyl-D-aspartic acid receptors on striatal neurons are essential for cocaine cue reactivity in mice. Biological Psychiatry. 67: 778-80. PMID 20149346 DOI: 10.1016/J.Biopsych.2009.12.023  0.702
2009 Suzuki G, Harper KM, Hiramoto T, Funke B, Lee M, Kang G, Buell M, Geyer MA, Kucherlapati R, Morrow B, Männistö PT, Agatsuma S, Hiroi N. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Human Molecular Genetics. 18: 3914-25. PMID 19617637 DOI: 10.1093/Hmg/Ddp334  0.78
2009 Suzuki G, Harper KM, Hiramoto T, Sawamura T, Lee M, Kang G, Tanigaki K, Buell M, Geyer MA, Trimble WS, Agatsuma S, Hiroi N. Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice. Human Molecular Genetics. 18: 1652-60. PMID 19240081 DOI: 10.1093/Hmg/Ddp086  0.783
2009 Hiroi N, Scott D. Constitutional mechanisms of vulnerability and resilience to nicotine dependence. Molecular Psychiatry. 14: 653-67. PMID 19238150 DOI: 10.1038/Mp.2009.16  0.319
2009 Hiramoto T, Suzuki G, Kang G, Funke B, Watanabe Y, Kucherlapati R, Morrow B, Hiroi N. Tbx1 heterozygosity impairs working memory in mice Neuroscience Research. 65: S121-S122. DOI: 10.1016/J.Neures.2009.09.576  0.68
2007 Zhu H, Lee M, Agatsuma S, Hiroi N. Pleiotropic impact of constitutive fosB inactivation on nicotine-induced behavioral alterations and stress-related traits in mice. Human Molecular Genetics. 16: 820-36. PMID 17468183 DOI: 10.1093/Hmg/Ddm027  0.81
2006 Agatsuma S, Lee M, Zhu H, Chen K, Shih JC, Seif I, Hiroi N. Monoamine oxidase A knockout mice exhibit impaired nicotine preference but normal responses to novel stimuli. Human Molecular Genetics. 15: 2721-31. PMID 16893910 DOI: 10.1093/Hmg/Ddl206  0.79
2005 Hiroi N, Zhu H, Lee M, Funke B, Arai M, Itokawa M, Kucherlapati R, Morrow B, Sawamura T, Agatsuma S. A 200-kb region of human chromosome 22q11.2 confers antipsychotic-responsive behavioral abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 19132-7. PMID 16365290 DOI: 10.1073/Pnas.0509635102  0.789
2005 Agatsuma S, Hiroi N. [Chromosome 22q11 and schizophrenia]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 25: 79-84. PMID 16220657  0.663
2005 Zhu H, Lee M, Guan F, Agatsuma S, Scott D, Fabrizio K, Fienberg AA, Hiroi N. DARPP-32 phosphorylation opposes the behavioral effects of nicotine. Biological Psychiatry. 58: 981-9. PMID 16084497 DOI: 10.1016/J.Biopsych.2005.05.026  0.784
2005 Hiroi N, Agatsuma S. Genetic susceptibility to substance dependence. Molecular Psychiatry. 10: 336-44. PMID 15583701 DOI: 10.1038/Sj.Mp.4001622  0.688
2004 Agatsuma S, Hiroi N. [Genetic basis of drug dependence and comorbid behavioral traits]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 24: 137-45. PMID 15291243  0.7
2004 Lee M, Chen K, Shih JC, Hiroi N. MAO-B knockout mice exhibit deficient habituation of locomotor activity but normal nicotine intake. Genes, Brain, and Behavior. 3: 216-27. PMID 15248867 DOI: 10.1111/J.1601-1848.2004.00074.X  0.521
2004 Grande C, Zhu H, Martin AB, Lee M, Ortiz O, Hiroi N, Moratalla R. Chronic treatment with atypical neuroleptics induces striosomal FosB/DeltaFosB expression in rats. Biological Psychiatry. 55: 457-63. PMID 15023572 DOI: 10.1016/J.Biopsych.2003.08.008  0.763
2002 Hiroi N, Martín AB, Grande C, Alberti I, Rivera A, Moratalla R. Molecular dissection of dopamine receptor signaling. Journal of Chemical Neuroanatomy. 23: 237-42. PMID 12048106 DOI: 10.1016/S0891-0618(02)00010-8  0.717
2001 Haile CN, Hiroi N, Nestler EJ, Kosten TA. Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. Synapse (New York, N.Y.). 41: 179-90. PMID 11391778 DOI: 10.1002/Syn.1073  0.489
1999 Atkins JB, Chlan-Fourney J, Nye HE, Hiroi N, Carlezon WA, Nestler EJ. Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs. Synapse (New York, N.Y.). 33: 118-28. PMID 10400890 DOI: 10.1002/(Sici)1098-2396(199908)33:2<118::Aid-Syn2>3.0.Co;2-L  0.647
1999 Hiroi N, Fienberg AA, Haile CN, Alburges M, Hanson GR, Greengard P, Nestler EJ. Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice. The European Journal of Neuroscience. 11: 1114-8. PMID 10103106 DOI: 10.1046/J.1460-9568.1999.00570.X  0.679
1998 Carlezon WA, Thome J, Olson VG, Lane-Ladd SB, Brodkin ES, Hiroi N, Duman RS, Neve RL, Nestler EJ. Regulation of cocaine reward by CREB. Science (New York, N.Y.). 282: 2272-5. PMID 9856954 DOI: 10.1126/Science.282.5397.2272  0.775
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6952-62. PMID 9712664 DOI: 10.1523/Jneurosci.18-17-06952.1998  0.629
1998 Fienberg AA, Hiroi N, Mermelstein PG, Song W, Snyder GL, Nishi A, Cheramy A, O'Callaghan JP, Miller DB, Cole DG, Corbett R, Haile CN, Cooper DC, Onn SP, Grace AA, et al. DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science (New York, N.Y.). 281: 838-42. PMID 9694658 DOI: 10.1126/Science.281.5378.838  0.655
1998 Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler EJ, Hen R. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 393: 175-8. PMID 9603521 DOI: 10.1038/30259  0.527
1998 White NM, Hiroi N. Preferential localization of self-stimulation sites in striosomes/patches in the rat striatum. Proceedings of the National Academy of Sciences of the United States of America. 95: 6486-91. PMID 9600993 DOI: 10.1073/Pnas.95.11.6486  0.565
1998 Hiroi N, Nestler EJ. Nuclear memory: gene transcription and behavior. Advances in Pharmacology (San Diego, Calif.). 42: 1037-41. PMID 9328075 DOI: 10.1016/S1054-3589(08)60924-2  0.468
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential Role of thefosB Gene in Molecular, Cellular, and Behavioral Actions of Chronic Electroconvulsive Seizures The Journal of Neuroscience. 18: 6952-6962. DOI: 10.1523/JNEUROSCI.18-17-06952.1998  0.533
1997 Hiroi N, Brown JR, Haile CN, Ye H, Greenberg ME, Nestler EJ. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proceedings of the National Academy of Sciences of the United States of America. 94: 10397-402. PMID 9294222 DOI: 10.1073/Pnas.94.19.10397  0.639
1996 Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 8019-26. PMID 8987828 DOI: 10.1523/Jneurosci.16-24-08019.1996  0.502
1996 Hiroi N, Graybiel AM. Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatum. The Journal of Comparative Neurology. 374: 70-83. PMID 8891947 DOI: 10.1002/(Sici)1096-9861(19961007)374:1<70::Aid-Cne5>3.0.Co;2-K  0.546
1996 Berhow MT, Hiroi N, Nestler EJ. Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4707-15. PMID 8764658 DOI: 10.1523/Jneurosci.16-15-04707.1996  0.488
1995 Chen J, Nye HE, Kelz MB, Hiroi N, Nakabeppu Y, Hope BT, Nestler EJ. Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. Molecular Pharmacology. 48: 880-9. PMID 7476919  0.626
1994 Xu M, Moratalla R, Gold LH, Hiroi N, Koob GF, Graybiel AM, Tonegawa S. Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell. 79: 729-42. PMID 7954836 DOI: 10.1016/0092-8674(94)90557-6  0.789
1993 Hiroi N, White NM. The ventral pallidum area is involved in the acquisition but not expression of the amphetamine conditioned place preference. Neuroscience Letters. 156: 9-12. PMID 8414197 DOI: 10.1016/0304-3940(93)90426-L  0.586
1993 White NM, Hiroi N. Amphetamine conditioned cue preference and the neurobiology of drug-seeking Seminars in Neuroscience. 5: 329-336. DOI: 10.1016/S1044-5765(05)80040-5  0.619
1992 White NM, Hiroi N. Pipradrol conditioned place preference is blocked by SCH23390. Pharmacology, Biochemistry, and Behavior. 43: 377-80. PMID 1359572 DOI: 10.1016/0091-3057(92)90165-C  0.596
1991 Hiroi N, White NM. The lateral nucleus of the amygdala mediates expression of the amphetamine-produced conditioned place preference. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2107-16. PMID 2066777 DOI: 10.1523/Jneurosci.11-07-02107.1991  0.329
1991 Hiroi N, White NM. The amphetamine conditioned place preference: differential involvement of dopamine receptor subtypes and two dopaminergic terminal areas. Brain Research. 552: 141-52. PMID 1833032 DOI: 10.1016/0006-8993(91)90672-I  0.612
1991 White NM, Packard MG, Hiroi N. Place conditioning with dopamine D1 and D2 agonists injected peripherally or into nucleus accumbens. Psychopharmacology. 103: 271-6. PMID 1674160 DOI: 10.1007/Bf02244216  0.712
1990 Hiroi N, White NM. The reserpine-sensitive dopamine pool mediates (+)-amphetamine-conditioned reward in the place preference paradigm. Brain Research. 510: 33-42. PMID 2322845 DOI: 10.1016/0006-8993(90)90724-P  0.603
1989 Hiroi N, White NM. Conditioned stereotypy: behavioral specification of the UCS and pharmacological investigation of the neural change. Pharmacology, Biochemistry, and Behavior. 32: 249-58. PMID 2543991 DOI: 10.1016/0091-3057(89)90241-4  0.623
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