| Year |
Citation |
Score |
| 2023 |
Sourty M, Nasseef MT, Champagnol-Di Liberti C, Mondino M, Noblet V, Parise EM, Markovic T, Browne CJ, Darcq E, Nestler EJ, Kieffer BL. Manipulating ΔFOSB in D1-type Medium Spiny Neurons of the nucleus accumbens reshapes whole brain functional connectivity. Biological Psychiatry. PMID 37517704 DOI: 10.1016/j.biopsych.2023.07.013 |
0.314 |
|
| 2023 |
Gyles TM, Nestler EJ, Parise EM. Advancing preclinical chronic stress models to promote therapeutic discovery for human stress disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37349475 DOI: 10.1038/s41386-023-01625-0 |
0.682 |
|
| 2023 |
Browne CJ, Futamura R, Minier-Toribio A, Hicks EM, Ramakrishnan A, Martínez-Rivera FJ, Estill M, Godino A, Parise EM, Torres-Berrío A, Cunningham AM, Hamilton PJ, Walker DM, Huckins LM, Hurd YL, ... ... Nestler EJ, et al. Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice. Science Advances. 9: eadg8558. PMID 37294757 DOI: 10.1126/sciadv.adg8558 |
0.818 |
|
| 2023 |
Pryce KD, Serafini RA, Ramakrishnan A, Nicolais A, Giosan IM, Polizu C, Torres-Berrío A, Vuppala S, Kronman H, Ruiz A, Gaspari S, Peña CJ, Sakloth F, Mitsi V, van Duzer J, ... ... Nestler EJ, et al. Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury. Nature Neuroscience. PMID 37291337 DOI: 10.1038/s41593-023-01350-3 |
0.809 |
|
| 2023 |
Torres-Berrío A, Estill M, Ramakrishnan A, Kronman H, Patel V, Minier-Toribio A, Issler O, Browne CJ, Parise EM, van der Zee Y, Walker D, Martínez-Rivera FJ, Lardner CK, Cuttoli RD, Russo SJ, ... ... Nestler EJ, et al. Monomethylation of Lysine 27 at Histone 3 Confers Lifelong Susceptibility to Stress. Biorxiv : the Preprint Server For Biology. PMID 37214877 DOI: 10.1101/2023.05.08.539829 |
0.82 |
|
| 2023 |
Mansouri S, Pessoni AM, Rivera AM, Tamminga CA, Parise E, Turecki G, Nestler EJ, Chen TH, Labonté B. Transcriptional dissection of symptomatic profiles across the brain of men and women with depression. Biorxiv : the Preprint Server For Biology. PMID 37131585 DOI: 10.1101/2023.04.21.537733 |
0.804 |
|
| 2023 |
Yeh SY, Estill M, Lardner CK, Browne CJ, Minier-Toribio A, Futamura R, Beach K, McManus CA, Xu SJ, Zhang S, Heller EA, Shen L, Nestler EJ. Cell Type-Specific Whole-Genome Landscape of ΔFOSB Binding in the Nucleus Accumbens After Chronic Cocaine Exposure. Biological Psychiatry. PMID 36906500 DOI: 10.1016/j.biopsych.2022.12.021 |
0.836 |
|
| 2023 |
Godino A, Salery M, Durand-de Cuttoli R, Estill MS, Holt LM, Futamura R, Browne CJ, Mews P, Hamilton PJ, Neve RL, Shen L, Russo SJ, Nestler EJ. Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards. Neuron. PMID 36889314 DOI: 10.1016/j.neuron.2023.02.013 |
0.836 |
|
| 2023 |
Russo S, Cathomas F, Lin HY, Chan K, Li L, Cuttoli RD, Parise L, Aubry A, Muhareb S, Desland F, Shimo Y, Ramakrishnan A, Estill M, Ferrer-Perez C, Parise E, ... ... Nestler E, et al. Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research Square. PMID 36778505 DOI: 10.21203/rs.3.rs-1647827/v1 |
0.801 |
|
| 2023 |
Mews P, Cunningham AM, Scarpa J, Ramakrishnan A, Hicks EM, Bolnick S, Garamszegi S, Shen L, Mash DC, Nestler EJ. Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science Advances. 9: eadd8946. PMID 36763659 DOI: 10.1126/sciadv.add8946 |
0.315 |
|
| 2023 |
Browne CJ, Futamura R, Minier-Toribio A, Hicks EM, Ramakrishnan A, Martínez-Rivera F, Estill M, Godino A, Parise EM, Torres-Berrío A, Cunningham AM, Hamilton PJ, Walker DM, Huckins LM, Hurd YL, ... ... Nestler EJ, et al. Transcriptional signatures of heroin intake and seeking throughout the brain reward circuit. Biorxiv : the Preprint Server For Biology. PMID 36711574 DOI: 10.1101/2023.01.11.523688 |
0.83 |
|
| 2022 |
Sweis BM, Nestler EJ. Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery. Plos Biology. 20: e3001904. PMID 36480527 DOI: 10.1371/journal.pbio.3001904 |
0.784 |
|
| 2022 |
Issler O, van der Zee YY, Ramakrishnan A, Xia S, Zinsmaier AK, Tan C, Li W, Browne CJ, Walker DM, Salery M, Torres-Berrío A, Futamura R, Duffy JE, Labonte B, Girgenti MJ, ... ... Nestler EJ, et al. The long noncoding RNA FEDORA is a cell type- and sex-specific regulator of depression. Science Advances. 8: eabn9494. PMID 36449610 DOI: 10.1126/sciadv.abn9494 |
0.81 |
|
| 2022 |
Durand-de Cuttoli R, Martínez-Rivera FJ, Li L, Minier-Toribio A, Holt LM, Cathomas F, Yasmin F, Elhassa SO, Shaikh JF, Ahmed S, Russo SJ, Nestler EJ, Sweis BM. Distinct forms of regret linked to resilience versus susceptibility to stress are regulated by region-specific CREB function in mice. Science Advances. 8: eadd5579. PMID 36260683 DOI: 10.1126/sciadv.add5579 |
0.81 |
|
| 2022 |
Nahvi R, Tanelian A, Nwokafor C, Godino A, Parise E, Estill M, Nestler EJ, Sabban EL. Transcriptome Profiles Associated with Resilience and Susceptibility to Single Prolonged Stress in the Locus Coeruleus and Nucleus Accumbens in Male Sprague-Dawley Rats. Behavioural Brain Research. 114162. PMID 36257560 DOI: 10.1016/j.bbr.2022.114162 |
0.703 |
|
| 2022 |
Teague CD, Picone JA, Wright WJ, Browne CJ, Silva GM, Futamura R, Minier-Toribio A, Estill ME, Ramakrishnan A, Martinez-Rivera FJ, Godino A, Parise EM, Schmidt KH, Pulido NV, Lorsch ZS, ... ... Nestler EJ, et al. CREB Binding at the Zfp189 Promoter Within Medium Spiny Neuron Subtypes Differentially Regulates Behavioral and Physiological Adaptations Over the Course of Cocaine Use. Biological Psychiatry. PMID 36253194 DOI: 10.1016/j.biopsych.2022.07.022 |
0.838 |
|
| 2022 |
Tan B, Nöbauer T, Browne CJ, Nestler EJ, Vaziri A, Friedman JM. Dynamic processing of hunger and thirst by common mesolimbic neural ensembles. Proceedings of the National Academy of Sciences of the United States of America. 119: e2211688119. PMID 36252036 DOI: 10.1073/pnas.2211688119 |
0.714 |
|
| 2022 |
Walker DM, Zhou X, Cunningham AM, Ramakrishnan A, Cates HM, Lardner CK, Peña CJ, Bagot RC, Issler O, Van der Zee Y, Lipschultz AP, Godino A, Browne CJ, Hodes GE, Parise EM, ... ... Nestler EJ, et al. Crystallin Mu in Medial Amygdala Mediates the Effect of Social Experience on Cocaine Seeking in Males but Not in Females. Biological Psychiatry. PMID 36182529 DOI: 10.1016/j.biopsych.2022.06.026 |
0.8 |
|
| 2022 |
Williams AV, Peña CJ, Ramos-Maciel S, Laman-Maharg A, Ordoñez-Sanchez E, Britton M, Durbin-Johnson B, Settles M, Hao R, Yokoyama S, Xu C, Luo PX, Dwyer T, Bhela S, Black AM, ... ... Nestler EJ, et al. Comparative Transcriptional Analyses in the Nucleus Accumbens Identifies RGS2 as a Key Mediator of Depression-Related Behavior. Biological Psychiatry. PMID 36075764 DOI: 10.1016/j.biopsych.2022.06.030 |
0.801 |
|
| 2022 |
Kumar A, Aglyamova G, Yim YY, Bailey AO, Lynch HM, Powell RT, Nguyen ND, Rosenthal Z, Zhao WN, Li Y, Chen J, Fan S, Lee H, Russell WK, Stephan C, ... ... Nestler EJ, et al. Chemically targeting the redox switch in AP1 transcription factor ΔFOSB. Nucleic Acids Research. PMID 36039764 DOI: 10.1093/nar/gkac710 |
0.574 |
|
| 2022 |
van der Zee YY, Eijssen LMT, Mews P, Ramakrishnan A, Alvarez K, Lardner CK, Cates HM, Walker DM, Torres-Berrío A, Browne CJ, Cunningham A, Cathomas F, Kronman H, Parise EM, de Nijs L, ... ... Nestler EJ, et al. Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression. Molecular Psychiatry. PMID 35902629 DOI: 10.1038/s41380-022-01712-6 |
0.794 |
|
| 2022 |
Mizrachi Zer-Aviv T, Islami L, Hamilton PJ, Parise EM, Nestler EJ, Sbarski B, Akirav I. Enhancing Endocannabinoid Signaling via β-Catenin in the Nucleus Accumbens Attenuates PTSD- and Depression-like Behavior of Male Rats. Biomedicines. 10. PMID 35892688 DOI: 10.3390/biomedicines10081789 |
0.757 |
|
| 2022 |
Morel C, Montgomery SE, Li L, Durand-de Cuttoli R, Teichman EM, Juarez B, Tzavaras N, Ku SM, Flanigan ME, Cai M, Walsh JJ, Russo SJ, Nestler EJ, Calipari ES, Friedman AK, et al. Midbrain projection to the basolateral amygdala encodes anxiety-like but not depression-like behaviors. Nature Communications. 13: 1532. PMID 35318315 DOI: 10.1038/s41467-022-29155-1 |
0.81 |
|
| 2022 |
Cathomas F, Holt LM, Parise EM, Liu J, Murrough JW, Casaccia P, Nestler EJ, Russo SJ. Beyond the neuron: Role of non-neuronal cells in stress disorders. Neuron. PMID 35182484 DOI: 10.1016/j.neuron.2022.01.033 |
0.792 |
|
| 2022 |
Cathomas F, Bevilacqua L, Ramakrishnan A, Kronman H, Costi S, Schneider M, Chan KL, Li L, Nestler EJ, Shen L, Charney DS, Russo SJ, Murrough JW. Whole blood transcriptional signatures associated with rapid antidepressant response to ketamine in patients with treatment resistant depression. Translational Psychiatry. 12: 12. PMID 35013133 DOI: 10.1038/s41398-021-01712-0 |
0.722 |
|
| 2022 |
Walker DM, Cunningham AM, Nestler EJ. Reply to: Multiple Comparisons and Inappropriate Statistical Testing Lead to Spurious Sex Differences in Gene Expression. Biological Psychiatry. 91: e3-e5. PMID 34674832 DOI: 10.1016/j.biopsych.2021.08.006 |
0.602 |
|
| 2021 |
Vaillancourt K, Chen GG, Fiori L, Maussion G, Yerko V, Théroux JF, Ernst C, Labonté B, Calipari E, Nestler EJ, Nagy C, Mechawar N, Mash DC, Turecki G. Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum. Iscience. 24: 103169. PMID 34693223 DOI: 10.1016/j.isci.2021.103169 |
0.818 |
|
| 2021 |
Lardner CK, van der Zee Y, Estill MS, Kronman HG, Salery M, Cunningham AM, Godino A, Parise EM, Kim JH, Neve RL, Shen L, Hamilton PJ, Nestler EJ. Gene-Targeted, CREB-Mediated Induction of ΔFosB Controls Distinct Downstream Transcriptional Patterns Within D1 and D2 Medium Spiny Neurons. Biological Psychiatry. PMID 34425966 DOI: 10.1016/j.biopsych.2021.06.017 |
0.792 |
|
| 2021 |
Parise EM, Parise LF, Sial OK, Cardona-Acosta AM, Gyles TM, Juarez B, Chaudhury D, Han MH, Nestler EJ, Bolaños-Guzmán CA. The Resilient Phenotype Induced by Prophylactic Ketamine Exposure During Adolescence Is Mediated by the Ventral Tegmental Area-Nucleus Accumbens Pathway. Biological Psychiatry. PMID 34247781 DOI: 10.1016/j.biopsych.2021.05.002 |
0.809 |
|
| 2021 |
Kazim SF, Sharma A, Saroja SR, Seo JH, Larson CS, Ramakrishnan A, Wang M, Blitzer RD, Shen L, Peña CJ, Crary JF, Shimoda LA, Zhang B, Nestler EJ, Pereira AC. Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures. Biological Psychiatry. PMID 34130857 DOI: 10.1016/j.biopsych.2021.02.973 |
0.604 |
|
| 2021 |
Kemény LV, Robinson KC, Hermann AL, Walker DM, Regan S, Yew YW, Lai YC, Theodosakis N, Rivera PD, Ding W, Yang L, Beyer T, Loh YE, Lo JA, van der Sande AAJ, ... ... Nestler EJ, et al. Vitamin D deficiency exacerbates UV/endorphin and opioid addiction. Science Advances. 7. PMID 34117054 DOI: 10.1126/sciadv.abe4577 |
0.721 |
|
| 2021 |
Cunningham AM, Walker DM, Ramakrishnan A, Doyle MA, Bagot RC, Cates HM, Peña CJ, Issler O, Lardner C, Browne C, Russo SJ, Shen L, Nestler EJ. Sperm transcriptional state associated with paternal transmission of stress phenotypes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34099514 DOI: 10.1523/JNEUROSCI.3192-20.2021 |
0.811 |
|
| 2021 |
Teague CD, Nestler EJ. Key transcription factors mediating cocaine-induced plasticity in the nucleus accumbens. Molecular Psychiatry. PMID 34079067 DOI: 10.1038/s41380-021-01163-5 |
0.363 |
|
| 2021 |
van der Zee YY, Lardner CK, Parise EM, Mews P, Ramakrishnan A, Patel V, Teague CD, Salery M, Walker DM, Browne CJ, Labonté B, Parise LF, Kronman H, Penã CJ, Torres-Berrío A, ... ... Nestler EJ, et al. Sex-Specific Role for SLIT1 in Regulating Stress Susceptibility. Biological Psychiatry. PMID 33896623 DOI: 10.1016/j.biopsych.2021.01.019 |
0.792 |
|
| 2021 |
Walker DM, Zhou X, Cunningham AM, Lipschultz AP, Ramakrishnan A, Cates HM, Bagot RC, Shen L, Zhang B, Nestler EJ. Sex-Specific Transcriptional Changes in Response to Adolescent Social Stress in the Brain's Reward Circuitry. Biological Psychiatry. PMID 33892914 DOI: 10.1016/j.biopsych.2021.02.964 |
0.803 |
|
| 2021 |
Wang J, Holt LM, Huang HH, Sesack SR, Nestler EJ, Dong Y. Astrocytes in cocaine addiction and beyond. Molecular Psychiatry. PMID 33837268 DOI: 10.1038/s41380-021-01080-7 |
0.307 |
|
| 2021 |
Kronman H, Torres-Berrío A, Sidoli S, Issler O, Godino A, Ramakrishnan A, Mews P, Lardner CK, Parise EM, Walker DM, van der Zee YY, Browne CJ, Boyce BF, Neve R, Garcia BA, ... ... Nestler EJ, et al. Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nature Neuroscience. PMID 33833436 DOI: 10.1038/s41593-021-00848-y |
0.792 |
|
| 2021 |
Estill M, Ribeiro E, Francoeur NJ, Smith ML, Sebra R, Yeh SY, Cunningham AM, Nestler EJ, Shen L. Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. Scientific Reports. 11: 6729. PMID 33762610 DOI: 10.1038/s41598-021-86068-7 |
0.673 |
|
| 2021 |
Kronman H, Torres-Berrío A, Sidoli S, Issler O, Godino A, Ramakrishnan A, Mews P, Lardner CK, Parise EM, Walker DM, van der Zee YY, Browne CJ, Boyce BF, Neve R, Garcia BA, ... ... Nestler EJ, et al. Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nature Neuroscience. PMID 33723435 DOI: 10.1038/s41593-021-00814-8 |
0.832 |
|
| 2021 |
McCullough KM, Missig G, Robble MA, Foilb AR, Wells AM, Hartmann J, Anderson KJ, Neve RL, Nestler EJ, Ressler KJ, Carlezon WA. Nucleus Accumbens Medium Spiny Neuron Subtypes Differentially Regulate Stress-Associated Alterations in Sleep Architecture. Biological Psychiatry. PMID 33715826 DOI: 10.1016/j.biopsych.2020.12.030 |
0.742 |
|
| 2020 |
Torres-Berrío A, Morgunova A, Giroux M, Cuesta S, Nestler EJ, Flores C. miR-218 in Adolescence Predicts and Mediates Vulnerability to Stress. Biological Psychiatry. PMID 33384174 DOI: 10.1016/j.biopsych.2020.10.015 |
0.744 |
|
| 2020 |
Lorsch ZS, Ambesi-Impiombato A, Zenowich R, Morganstern I, Leahy E, Bansal M, Nestler EJ, Hanania T. Computational Analysis of Multidimensional Behavioral Alterations After Chronic Social Defeat Stress. Biological Psychiatry. PMID 33309017 DOI: 10.1016/j.biopsych.2020.10.010 |
0.738 |
|
| 2020 |
Hamilton PJ, Chen EY, Tolstikov V, Peña CJ, Picone JA, Shah P, Panagopoulos K, Strat AN, Walker DM, Lorsch ZS, Robinson HL, Mervosh NL, Kiraly DD, Sarangarajan R, Narain NR, ... ... Nestler EJ, et al. Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum. Scientific Reports. 10: 18134. PMID 33093530 DOI: 10.1038/s41598-020-75114-5 |
0.819 |
|
| 2020 |
Wang J, Li KL, Shukla A, Beroun A, Ishikawa M, Huang X, Wang Y, Wang YQ, Yang Y, Bastola ND, Huang HH, Kramer LE, Chao T, Huang YH, Sesack SR, ... Nestler EJ, et al. Cocaine Triggers Astrocyte-Mediated Synaptogenesis. Biological Psychiatry. PMID 33069367 DOI: 10.1016/J.Biopsych.2020.08.012 |
0.386 |
|
| 2020 |
Vaillancourt K, Yang J, Chen GG, Yerko V, Théroux JF, Aouabed Z, Lopez A, Thibeault KC, Calipari ES, Labonté B, Mechawar N, Ernst C, Nagy C, Forné T, Nestler EJ, et al. Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. Molecular Psychiatry. PMID 33046833 DOI: 10.1038/s41380-020-00909-x |
0.814 |
|
| 2020 |
Vaid A, Somani S, Russak AJ, De Freitas JK, Chaudhry FF, Paranjpe I, Johnson KW, Lee SJ, Miotto R, Richter F, Zhao S, Beckmann ND, Naik N, Kia A, Timsina P, ... ... Nestler EJ, et al. Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients: A Cohort Study. Journal of Medical Internet Research. PMID 33027032 DOI: 10.2196/24018 |
0.303 |
|
| 2020 |
Nestler EJ, Waxman SG. Resilience to Stress and Resilience to Pain: Lessons from Molecular Neurobiology and Genetics. Trends in Molecular Medicine. 26: 924-935. PMID 32976800 DOI: 10.1016/j.molmed.2020.03.007 |
0.32 |
|
| 2020 |
Zhao JY, Liang L, Gu X, Li Z, Wu S, Sun L, Atianjoh FE, Feng J, Mo K, Jia S, Lutz BM, Bekker A, Nestler EJ, Tao YX. Author Correction: DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons. Nature Communications. 11: 4696. PMID 32929092 DOI: 10.1038/S41467-020-18562-X |
0.515 |
|
| 2020 |
Xu H, Brown AN, Waddell NJ, Liu X, Kaplan GJ, Chitaman JM, Stockman V, Hedinger RL, Adams R, Abreu K, Shen L, Neve R, Wang Z, Nestler EJ, Feng J. Role of Long Noncoding RNA Gas5 in Cocaine Action. Biological Psychiatry. PMID 32711952 DOI: 10.1016/J.Biopsych.2020.05.004 |
0.792 |
|
| 2020 |
Yim YY, Teague CD, Nestler EJ. In vivo locus-specific editing of the neuroepigenome. Nature Reviews. Neuroscience. PMID 32704051 DOI: 10.1038/s41583-020-0334-y |
0.35 |
|
| 2020 |
Dash S, Balasubramaniam M, Martínez-Rivera FJ, Godino A, Peck EG, Patnaik S, Suar M, Calipari ES, Nestler EJ, Villalta F, Dash C, Pandhare J. Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells. Scientific Reports. 10: 11197. PMID 32641757 DOI: 10.1038/S41598-020-68144-6 |
0.624 |
|
| 2020 |
Lee JH, Ribeiro EA, Kim J, Ko B, Kronman H, Jeong YH, Kim JK, Janak PH, Nestler EJ, Koo JW, Kim JH. Dopaminergic Regulation of Nucleus Accumbens Cholinergic Interneurons Demarcates Susceptibility to Cocaine Addiction. Biological Psychiatry. PMID 32622465 DOI: 10.1016/J.Biopsych.2020.05.003 |
0.824 |
|
| 2020 |
Torres-Berrío A, Hernandez G, Nestler EJ, Flores C. The Netrin-1/DCC Guidance Cue Pathway as a Molecular Target in Depression: Translational Evidence. Biological Psychiatry. PMID 32593422 DOI: 10.1016/j.biopsych.2020.04.025 |
0.771 |
|
| 2020 |
Yin Z, Venkannagari H, Lynch H, Aglyamova G, Bhandari M, Machius M, Nestler EJ, Robison AJ, Rudenko G. Self-assembly of the bZIP transcription factor ΔFosB. Current Research in Structural Biology. 2: 1-13. PMID 32542236 DOI: 10.1016/j.crstbi.2019.12.001 |
0.613 |
|
| 2020 |
Issler O, van der Zee YY, Ramakrishnan A, Wang J, Tan C, Loh YE, Purushothaman I, Walker DM, Lorsch ZS, Hamilton PJ, Peña CJ, Flaherty E, Hartley BJ, Torres-Berrío A, Parise EM, ... ... Nestler EJ, et al. Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression. Neuron. PMID 32304628 DOI: 10.1016/J.Neuron.2020.03.023 |
0.811 |
|
| 2020 |
Flanigan ME, Aleyasin H, Li L, Burnett CJ, Chan KL, LeClair KB, Lucas EK, Matikainen-Ankney B, Durand-de Cuttoli R, Takahashi A, Menard C, Pfau ML, Golden SA, Bouchard S, Calipari ES, ... Nestler EJ, et al. Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice. Nature Neuroscience. PMID 32284606 DOI: 10.1038/S41593-020-0617-7 |
0.805 |
|
| 2020 |
Scarpa JR, Fatma M, Loh YE, Traore SR, Stefan T, Chen TH, Nestler EJ, Labonté B. Shared Transcriptional Signatures in Major Depressive Disorder and Mouse Chronic Stress Models. Biological Psychiatry. PMID 32169281 DOI: 10.1016/J.Biopsych.2019.12.029 |
0.691 |
|
| 2020 |
Pignatelli M, Tejeda HA, Barker DJ, Bontempi L, Wu J, Lopez A, Palma Ribeiro S, Lucantonio F, Parise EM, Torres-Berrio A, Alvarez-Bagnarol Y, Marino RAM, Cai ZL, Xue M, Morales M, ... ... Nestler EJ, et al. Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice. Molecular Psychiatry. PMID 32161361 DOI: 10.1038/S41380-020-0686-8 |
0.809 |
|
| 2020 |
Krystal JH, Nestler EJ, Picciotto MR. Ronald S. Duman, Ph.D. (1954-2020). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32076104 DOI: 10.1038/S41386-020-0642-Y |
0.635 |
|
| 2020 |
Labonté B, Abdallah K, Maussion G, Yerko V, Yang J, Bittar T, Quessy F, Golden SA, Navarro L, Checknita D, Gigek C, Lopez JP, Neve RL, Russo SJ, Tremblay RE, ... ... Nestler EJ, et al. Regulation of impulsive and aggressive behaviours by a novel lncRNA. Molecular Psychiatry. PMID 31907380 DOI: 10.1038/S41380-019-0637-4 |
0.802 |
|
| 2020 |
Pryce KD, Kronman H, Ramakrishnan A, Torres-Berrio A, Polizu CD, Pena C, Shen LD, Nestler E, Zachariou V. Oxycodone‐induced Gene adaptations in the brain reward center in a murine Model of Neuropathic pain The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04088 |
0.786 |
|
| 2020 |
Nestler EJ, Krystal JH. Ronald S. Duman (1954–2020) Neuron. 105: 769-770. DOI: 10.1016/J.Neuron.2020.02.018 |
0.362 |
|
| 2020 |
Yin Z, Venkannagari H, Lynch H, Aglyamova G, Bhandari M, Machius M, Nestler EJ, Robison AJ, Rudenko G. Self-assembly of the bZIP transcription factor ΔFosB Current Research in Structural Biology. 2: 1-13. DOI: 10.1016/j.crstbi.2019.12.001 |
0.719 |
|
| 2019 |
Torres-Berrío A, Issler O, Parise EM, Nestler EJ. Unraveling the epigenetic landscape of depression: focus on early life stress
. Dialogues in Clinical Neuroscience. 21: 341-357. PMID 31949402 DOI: 10.31887/DCNS.2019.21.4/enestler |
0.807 |
|
| 2019 |
Wright WJ, Graziane NM, Neumann PA, Hamilton PJ, Cates HM, Fuerst L, Spenceley A, MacKinnon-Booth N, Iyer K, Huang YH, Shaham Y, Schlüter OM, Nestler EJ, Dong Y. Silent synapses dictate cocaine memory destabilization and reconsolidation. Nature Neuroscience. PMID 31792465 DOI: 10.1038/S41593-019-0537-6 |
0.777 |
|
| 2019 |
Peña CJ, Smith M, Ramakrishnan A, Cates HM, Bagot RC, Kronman HG, Patel B, Chang AB, Purushothaman I, Dudley J, Morishita H, Shen L, Nestler EJ. Early life stress alters transcriptomic patterning across reward circuitry in male and female mice. Nature Communications. 10: 5098. PMID 31704941 DOI: 10.1038/S41467-019-13085-6 |
0.819 |
|
| 2019 |
Cunningham AM, Walker DM, Nestler EJ. Paternal Transgenerational Epigenetic Mechanisms Mediating Stress Phenotypes of Offspring. The European Journal of Neuroscience. PMID 31549423 DOI: 10.1111/Ejn.14582 |
0.69 |
|
| 2019 |
Browne CJ, Godino A, Salery M, Nestler EJ. Epigenetic Mechanisms of Opioid Addiction. Biological Psychiatry. PMID 31477236 DOI: 10.1016/j.biopsych.2019.06.027 |
0.76 |
|
| 2019 |
Nasca C, Menard C, Hodes G, Bigio B, Pena C, Lorsch Z, Zelli D, Ferris A, Kana V, Purushothaman I, Dobbin J, Nassim M, DeAngelis P, Merad M, Rasgon N, ... ... Nestler EJ, et al. Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress. Biological Psychiatry. 86: 483-491. PMID 31466563 DOI: 10.1016/J.Biopsych.2019.06.030 |
0.795 |
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| 2019 |
Lorsch ZS, Hamilton PJ, Ramakrishnan A, Parise EM, Salery M, Wright WJ, Lepack AE, Mews P, Issler O, McKenzie A, Zhou X, Parise LF, Pirpinias ST, Ortiz Torres I, Kronman HG, ... ... Nestler EJ, et al. Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nature Neuroscience. PMID 31427770 DOI: 10.1038/S41593-019-0462-8 |
0.808 |
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| 2019 |
Koo JW, Chaudhury D, Han MH, Nestler EJ. Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression. Biological Psychiatry. PMID 31327473 DOI: 10.1016/j.biopsych.2019.05.020 |
0.701 |
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| 2019 |
Hamilton PJ, Nestler EJ. Epigenetics and addiction. Current Opinion in Neurobiology. 59: 128-136. PMID 31255844 DOI: 10.1016/J.Conb.2019.05.005 |
0.612 |
|
| 2019 |
de Meireles LCF, Galvão F, Walker DM, Cechinel LR, de Souza Grefenhagen ÁI, Andrade G, Palazzo RP, Lovatel GA, Basso CG, Nestler EJ, Siqueira IR. Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications. Molecular Neurobiology. PMID 31250382 DOI: 10.1007/S12035-019-01675-W |
0.64 |
|
| 2019 |
Cathomas F, Murrough JW, Nestler EJ, Han MH, Russo SJ. Neurobiology of Resilience: Interface Between Mind and Body. Biological Psychiatry. PMID 31178098 DOI: 10.1016/J.Biopsych.2019.04.011 |
0.736 |
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| 2019 |
Kronman H, Richter F, Labonté B, Chandra R, Zhao S, Hoffman G, Lobo MK, Schadt EE, Nestler EJ. Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons. Scientific Reports. 9: 8350. PMID 31171808 DOI: 10.1038/S41598-019-44798-9 |
0.75 |
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| 2019 |
Calipari ES, Godino A, Salery M, Damez-Werno DM, Cahill ME, Werner CT, Gancarz AM, Peck EG, Jlayer Z, Rabkin J, Landry JA, Smith ACW, Defilippi P, Kenny PJ, Hurd YL, ... ... Nestler EJ, et al. Synaptic microtubule-associated protein EB3 and SRC phosphorylation mediate structural and behavioral adaptations during withdrawal from cocaine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31092585 DOI: 10.1523/Jneurosci.0024-19.2019 |
0.833 |
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| 2019 |
Bale TL, Abel T, Akil H, Carlezon WA, Moghaddam B, Nestler EJ, Ressler KJ, Thompson SM. The critical importance of basic animal research for neuropsychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31048727 DOI: 10.1038/s41386-019-0405-9 |
0.537 |
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| 2019 |
Walker DM, Cunningham AM, Gregory JK, Nestler EJ. Long-Term Behavioral Effects of Post-weaning Social Isolation in Males and Females. Frontiers in Behavioral Neuroscience. 13: 66. PMID 31031604 DOI: 10.3389/Fnbeh.2019.00066 |
0.684 |
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| 2019 |
Torres-Berrío A, Nouel D, Cuesta S, Parise EM, Restrepo-Lozano JM, Larochelle P, Nestler EJ, Flores C. MiR-218: a molecular switch and potential biomarker of susceptibility to stress. Molecular Psychiatry. PMID 30980043 DOI: 10.1038/s41380-019-0421-5 |
0.783 |
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| 2019 |
Cates HM, Lardner CK, Bagot RC, Neve RL, Nestler EJ. Induction in Nucleus Accumbens by Cocaine Is Regulated by E2F3a. Eneuro. 6. PMID 30963104 DOI: 10.1523/ENEURO.0325-18.2019 |
0.835 |
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| 2019 |
Nestler EJ, Lüscher C. The Molecular Basis of Drug Addiction: Linking Epigenetic to Synaptic and Circuit Mechanisms. Neuron. 102: 48-59. PMID 30946825 DOI: 10.1016/j.neuron.2019.01.016 |
0.404 |
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| 2019 |
Mews P, Walker DM, Nestler EJ. Epigenetic Priming in Drug Addiction. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30936392 DOI: 10.1101/Sqb.2018.83.037663 |
0.704 |
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| 2019 |
Peña CJ, Nestler EJ, Bagot RC. Environmental Programming of Susceptibility and Resilience to Stress in Adulthood in Male Mice. Frontiers in Behavioral Neuroscience. 13: 40. PMID 30881296 DOI: 10.3389/Fnbeh.2019.00040 |
0.787 |
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| 2019 |
Labonté B, Jeong YH, Parise E, Issler O, Fatma M, Engmann O, Cho KA, Neve R, Nestler EJ, Koo JW. Gadd45b mediates depressive-like role through DNA demethylation. Scientific Reports. 9: 4615. PMID 30874581 DOI: 10.1038/S41598-019-40844-8 |
0.827 |
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| 2019 |
Ribeiro EA, Nectow AR, Pomeranz LE, Ekstrand MI, Koo JW, Nestler EJ. Viral labeling of neurons synaptically connected to nucleus accumbens somatostatin interneurons. Plos One. 14: e0213476. PMID 30845266 DOI: 10.1371/Journal.Pone.0213476 |
0.718 |
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| 2019 |
Föcking M, Sabherwal S, Cates HM, Scaife C, Dicker P, Hryniewiecka M, Wynne K, Rutten BPF, Lewis G, Cannon M, Nestler EJ, Heurich M, Cagney G, Zammit S, Cotter DR. Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress. Molecular Psychiatry. PMID 30635638 DOI: 10.1038/S41380-018-0306-Z |
0.713 |
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| 2019 |
Torres-Berrio A, Parise EM, Gyles T, Martínez-Rivera FJ, Browne CJ, Nestler EJ. Transcriptional signatures of treatment resistant depression in mouse models Ibro Reports. 6: S371. DOI: 10.1016/j.ibror.2019.07.1179 |
0.786 |
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| 2019 |
Yim YY, Browne CJ, Wang J, Wilson RS, Nairn AC, Dong Y, Nestler EJ. Proteomic profiling of nucleus accumbens synaptosomes following short- and long-term withdrawal from cocaine self-administration in mice Ibro Reports. 6: S371. DOI: 10.1016/j.ibror.2019.07.1178 |
0.782 |
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| 2019 |
Nestler EJ, Huganir RL. Paul Greengard (1925–2019) Cell. 177: 1365-1366. DOI: 10.1016/j.cell.2019.05.020 |
0.404 |
|
| 2019 |
Labonte B, Scarpa J, Loh E, Stefan T, Thraore R, Rosemary B, Chen TH, Nestler E. O22. Transcriptional Organization of Gene Networks in Human MDD and Their Correlates in Different Mouse Models of Stress Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.287 |
0.657 |
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| 2019 |
Pena C, Friedman A, Morel C, Ramakrishnan A, Neve R, Shen L, Han M, Nestler E. 130. OTX2 Mediates Transcriptional Impact of Early Life Stress in Mouse Ventral Tegmental Area Biological Psychiatry. 85: S54. DOI: 10.1016/J.Biopsych.2019.03.144 |
0.723 |
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| 2018 |
Anderson EM, Sun H, Guzman D, Taniguchi M, Cowan CW, Maze I, Nestler EJ, Self DW. Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30587852 DOI: 10.1038/S41386-018-0305-4 |
0.823 |
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| 2018 |
Cates HM, Bagot RC, Heller EA, Purushothaman I, Lardner CK, Walker DM, Peña CJ, Neve RL, Shen L, Nestler EJ. A novel role for E2F3b in regulating cocaine action in the prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30552390 DOI: 10.1038/S41386-018-0296-1 |
0.843 |
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| 2018 |
Tsankova N, Renthal W, Kumar A, Nestler EJ. Author Correction: Epigenetic regulation in psychiatric disorders. Nature Reviews. Neuroscience. PMID 30546104 DOI: 10.1038/S41583-018-0089-X |
0.673 |
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| 2018 |
Jiang C, Lin WJ, Labonté B, Tamminga CA, Turecki G, Nestler EJ, Russo SJ, Salton SR. VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30504797 DOI: 10.1038/S41386-018-0277-4 |
0.823 |
|
| 2018 |
Tan A, Costi S, Morris LS, Van Dam NT, Kautz M, Whitton AE, Friedman AK, Collins KA, Ahle G, Chadha N, Do B, Pizzagalli DA, Iosifescu DV, Nestler EJ, Han MH, et al. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular Psychiatry. PMID 30385872 DOI: 10.1038/S41380-018-0283-2 |
0.514 |
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| 2018 |
Zhang H, Chaudhury D, Nectow AR, Friedman AK, Zhang S, Juarez B, Liu H, Pfau ML, Aleyasin H, Jiang C, Crumiller M, Calipari ES, Ku SM, Morel C, Tzavaras N, ... ... Nestler EJ, et al. α- and β-Adrenergic Receptor-Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice. Biological Psychiatry. PMID 30336931 DOI: 10.1016/J.Biopsych.2018.08.020 |
0.81 |
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| 2018 |
Hamilton PJ, Lim CJ, Nestler EJ, Heller EA. Stereotaxic Surgery and Viral Delivery of Zinc-Finger Epigenetic Editing Tools in Rodent Brain. Methods in Molecular Biology (Clifton, N.J.). 1867: 229-238. PMID 30155827 DOI: 10.1007/978-1-4939-8799-3_17 |
0.654 |
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| 2018 |
Kaufman J, Wymbs NF, Montalvo-Ortiz JL, Orr C, Albaugh MD, Althoff R, O'Loughlin K, Holbrook H, Garavan H, Kearney C, Yang BZ, Zhao H, Peña C, Nestler EJ, Lee RS, et al. Methylation in OTX2 and related genes, maltreatment, and depression in children. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30089883 DOI: 10.1038/S41386-018-0157-Y |
0.678 |
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| 2018 |
Ribeiro EA, Salery M, Scarpa JR, Calipari ES, Hamilton PJ, Ku SM, Kronman H, Purushothaman I, Juarez B, Heshmati M, Doyle M, Lardner C, Burek D, Strat A, Pirpinias S, ... ... Nestler EJ, et al. Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine. Nature Communications. 9: 3149. PMID 30089879 DOI: 10.1038/S41467-018-05657-9 |
0.835 |
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| 2018 |
Cates HM, Li X, Purushothaman I, Kennedy PJ, Shen L, Shaham Y, Nestler EJ. Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30072726 DOI: 10.1038/S41386-018-0158-X |
0.794 |
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| 2018 |
Cahill ME, Browne C, Wang J, Hamilton PJ, Dong Y, Nestler EJ. Withdrawal from repeated morphine administration augments expression of the RhoA network in the nucleus accumbens to control synaptic structure. Journal of Neurochemistry. PMID 30071134 DOI: 10.1111/Jnc.14563 |
0.82 |
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| 2018 |
Peña CJ, Nestler EJ. Progress in Epigenetics of Depression. Progress in Molecular Biology and Translational Science. 157: 41-66. PMID 29933956 DOI: 10.1016/Bs.Pmbts.2017.12.011 |
0.679 |
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| 2018 |
Aleyasin H, Flanigan ME, Golden SA, Takahashi A, Menard C, Pfau ML, Multer J, Pina J, McCabe KA, Bhatti N, Hodes GE, Heshmati M, Neve RL, Nestler EJ, Heller EA, et al. Cell-type-specific role of ΔFosB in nucleus accumbens in modulating inter-male aggression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29891732 DOI: 10.1523/Jneurosci.0296-18.2018 |
0.823 |
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| 2018 |
Mul JD, Soto M, Cahill ME, Ryan RE, Takahashi H, So K, Zheng J, Croote DE, Hirshman MF, la Fleur SE, Nestler EJ, Goodyear LJ. Voluntary wheel running promotes resilience to chronic social defeat stress in mice: a role for nucleus accumbens ΔFosB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29875450 DOI: 10.1038/S41386-018-0103-Z |
0.428 |
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| 2018 |
Walker DM, Cates HM, Loh YE, Purushothaman I, Ramakrishnan A, Cahill KM, Lardner CK, Godino A, Kronman HG, Rabkin J, Lorsch ZS, Mews P, Doyle MA, Feng J, Labonté B, ... ... Nestler EJ, et al. Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain's Reward Circuitry. Biological Psychiatry. PMID 29861096 DOI: 10.1016/J.Biopsych.2018.04.009 |
0.823 |
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| 2018 |
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Nestler EJ, et al. Corrigendum: Sex-specific transcriptional signatures in human depression. Nature Medicine. 24: 525. PMID 29634684 DOI: 10.1038/Nm0418-525D |
0.784 |
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| 2018 |
Monteggia LM, Heimer H, Nestler EJ. Meeting Report: Can We Make Animal Models of Human Mental Illness? Biological Psychiatry. PMID 29606372 DOI: 10.1016/J.Biopsych.2018.02.010 |
0.562 |
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| 2018 |
Lorsch ZS, Loh YE, Purushothaman I, Walker DM, Parise EM, Salery M, Cahill ME, Hodes GE, Pfau ML, Kronman H, Hamilton PJ, Issler O, Labonté B, Symonds AE, Zucker M, ... ... Nestler EJ, et al. Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature Communications. 9: 1116. PMID 29549264 DOI: 10.1038/S41467-018-03567-4 |
0.825 |
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| 2018 |
Hamilton PJ, Lim CJ, Nestler EJ, Heller EA. Viral Expression of Epigenome Editing Tools in Rodent Brain Using Stereotaxic Surgery Techniques. Methods in Molecular Biology (Clifton, N.J.). 1767: 205-214. PMID 29524136 DOI: 10.1007/978-1-4939-7774-1_10 |
0.654 |
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| 2018 |
Hamilton PJ, Lim CJ, Nestler EJ, Heller EA. Neuroepigenetic Editing. Methods in Molecular Biology (Clifton, N.J.). 1767: 113-136. PMID 29524131 DOI: 10.1007/978-1-4939-7774-1_5 |
0.647 |
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| 2018 |
Hultman R, Ulrich K, Sachs BD, Blount C, Carlson DE, Ndubuizu N, Bagot RC, Parise EM, Vu MT, Gallagher NM, Wang J, Silva AJ, Deisseroth K, Mague SD, Caron MG, ... Nestler EJ, et al. Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability. Cell. PMID 29502969 DOI: 10.1016/J.Cell.2018.02.012 |
0.802 |
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| 2018 |
Walker DM, Nestler EJ. Neuroepigenetics and addiction. Handbook of Clinical Neurology. 148: 747-765. PMID 29478612 DOI: 10.1016/B978-0-444-64076-5.00048-X |
0.725 |
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| 2018 |
Calipari ES, Godino A, Peck EG, Salery M, Mervosh NL, Landry JA, Russo SJ, Hurd YL, Nestler EJ, Kiraly DD. Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine. Nature Communications. 9: 9. PMID 29339724 DOI: 10.1038/S41467-017-01881-X |
0.797 |
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| 2018 |
Issler O, Nestler EJ. The molecular basis for sex differences in depression susceptibility Current Opinion in Behavioral Sciences. 23: 1-6. DOI: 10.1016/j.cobeha.2017.12.019 |
0.358 |
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| 2018 |
Focking M, Cates H, Dicker P, Hryniewiecka M, Sabherwal S, de Nijs L, Cagney G, Nestler E, Rutten B, Cotter D. S90. Social Defeat Stress: A Plasma Proteomic Study to Identify Stress Susceptible-Associated and Resilience-Associated Biomarkers Biological Psychiatry. 83: S382. DOI: 10.1016/J.Biopsych.2018.02.981 |
0.704 |
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| 2018 |
Lorsch Z, Hamilton P, Lepack A, Mews P, Parise E, Alcantara L, Issler O, Ramakrishnan A, Purushothaman I, Loh YE, McKenzie A, Wang M, Maze I, Zhang B, Shen L, ... ... Nestler E, et al. O41. CREB-Zfp189 Interactions Regulate a Resilient-Specific Transcriptional Network in Animal Models of Depression Biological Psychiatry. 83: S125. DOI: 10.1016/J.Biopsych.2018.02.328 |
0.787 |
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| 2018 |
Feng J, Xu H, Brown A, Kaplan G, Nestler E. S256. Long-Noncoding Rna Gas5 is Associated With Cocaine Action Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.1148 |
0.798 |
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| 2018 |
Nasca C, Bigio B, Lee F, Zelli D, Young S, Lau T, Issler O, Menard C, Murrough J, Kocsis J, Russo S, Nestler E, Rasgon N, McEwen B. 86. Role of the Epigenetic Agent Acetyl-L-Carnitine as Gating Biomarker in Depression and Influences of Childhood Trauma Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.103 |
0.747 |
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| 2018 |
Murrough J, Tan A, Morris L, Costi S, Van Dam N, Stern E, Nestler E, Han M. 65. From Stress Resilience to Novel Therapeutics: KCNQ Channel Openers and Other Approaches Emerging From Translational Neuroscience Biological Psychiatry. 83: S27. DOI: 10.1016/J.Biopsych.2018.02.082 |
0.458 |
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| 2018 |
Pena C, Kronman H, Friedman A, Walker D, Cates H, Issler O, Loh YE, Bagot R, Ramakrishnan A, Purushothaman I, Zhu Y, Neve R, Shen L, Nestler E, Han M. 17. Lifelong Transcriptional, Epigenetic, and Neurophysiological Consequences of Early Life Stress in Mouse Brain Reward Circuitry Biological Psychiatry. 83: S7. DOI: 10.1016/J.Biopsych.2018.02.034 |
0.81 |
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| 2017 |
Li X, Carreria MB, Witonsky KR, Zeric T, Lofaro OM, Bossert JM, Zhang J, Surjono F, Richie CT, Harvey BK, Son H, Cowan CW, Nestler EJ, Shaham Y. Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving. Biological Psychiatry. PMID 29397902 DOI: 10.1016/J.Biopsych.2017.12.008 |
0.682 |
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| 2017 |
Cates HM, Heller EA, Lardner CK, Purushothaman I, Peña CJ, Walker DM, Cahill ME, Neve RL, Shen L, Bagot RC, Nestler EJ. Transcription Factor E2F3a in Nucleus Accumbens Affects Cocaine Action via Transcription and Alternative Splicing. Biological Psychiatry. PMID 29397901 DOI: 10.1016/J.Biopsych.2017.11.027 |
0.835 |
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| 2017 |
Anderson EM, Larson EB, Guzman D, Marie Wissman A, Neve RL, Nestler EJ, Self DW. Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29217682 DOI: 10.1523/Jneurosci.1657-17.2017 |
0.831 |
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| 2017 |
Jiang C, Lin WJ, Sadahiro M, Labonté B, Menard C, Pfau ML, Tamminga CA, Turecki G, Nestler EJ, Russo SJ, Salton SR. VGF function in depression and antidepressant efficacy. Molecular Psychiatry. PMID 29158577 DOI: 10.1038/Mp.2017.233 |
0.823 |
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| 2017 |
Takahashi A, Chung JR, Zhang S, Zhang H, Grossman Y, Aleyasin H, Flanigan ME, Pfau ML, Menard C, Dumitriu D, Hodes GE, McEwen BS, Nestler EJ, Han MH, Russo SJ. Establishment of a repeated social defeat stress model in female mice. Scientific Reports. 7: 12838. PMID 28993631 DOI: 10.1038/S41598-017-12811-8 |
0.8 |
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| 2017 |
Yu J, Yan Y, Li KL, Wang Y, Huang YH, Urban NN, Nestler EJ, Schlüter OM, Dong Y. Nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973852 DOI: 10.1073/Pnas.1707822114 |
0.405 |
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| 2017 |
Nätt D, Barchiesi R, Murad J, Feng J, Nestler EJ, Champagne FA, Thorsell A. Perinatal Malnutrition Leads to Sexually Dimorphic Behavioral Responses with Associated Epigenetic Changes in the Mouse Brain. Scientific Reports. 7: 11082. PMID 28894112 DOI: 10.1038/S41598-017-10803-2 |
0.708 |
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| 2017 |
Akil H, Gordon J, Hen R, Javitch J, Mayberg H, McEwen B, Meaney MJ, Nestler EJ. Treatment Resistant Depression: A Multi-Scale, Systems Biology Approach. Neuroscience and Biobehavioral Reviews. PMID 28859997 DOI: 10.1016/J.Neubiorev.2017.08.019 |
0.471 |
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| 2017 |
Dash S, Balasubramaniam M, Rana T, Godino A, Peck EG, Goodwin JS, Villalta F, Calipari ES, Nestler EJ, Dash C, Pandhare J. Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. Eneuro. 4. PMID 28828398 DOI: 10.1523/ENEURO.0089-17.2017 |
0.614 |
|
| 2017 |
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Nestler EJ, et al. Sex-specific transcriptional signatures in human depression. Nature Medicine. PMID 28825715 DOI: 10.1038/Nm.4386 |
0.812 |
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| 2017 |
Anderson EM, Wissman AM, Chemplanikal J, Buzin N, Guzman D, Larson EB, Neve RL, Nestler EJ, Cowan CW, Self DW. BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808012 DOI: 10.1073/Pnas.1702441114 |
0.827 |
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| 2017 |
Ribeiro EA, Scarpa JR, Garamszegi SP, Kasarskis A, Mash DC, Nestler EJ. Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder. Scientific Reports. 7: 5412. PMID 28710498 DOI: 10.1038/S41598-017-05720-3 |
0.707 |
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| 2017 |
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, ... ... Nestler EJ, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/Ng.3906 |
0.68 |
|
| 2017 |
Peña CJ, Kronman HG, Walker DM, Cates HM, Bagot RC, Purushothaman I, Issler O, Loh YE, Leong T, Kiraly DD, Goodman E, Neve RL, Shen L, Nestler EJ. Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2. Science (New York, N.Y.). 356: 1185-1188. PMID 28619944 DOI: 10.1126/Science.Aan4491 |
0.807 |
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| 2017 |
Muir J, Lorsch ZS, Ramakrishnan C, Deisseroth K, Nestler EJ, Calipari ES, Bagot RC. In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28589967 DOI: 10.1038/Npp.2017.122 |
0.819 |
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| 2017 |
Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, ... ... Nestler EJ, et al. Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biological Psychiatry. PMID 28577753 DOI: 10.1016/J.Biopsych.2017.04.013 |
0.836 |
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| 2017 |
Cahill ME, Walker DM, Gancarz AM, Wang ZJ, Lardner CK, Bagot RC, Neve RL, Dietz DM, Nestler EJ. The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling. Molecular Psychiatry. PMID 28555077 DOI: 10.1038/Mp.2017.116 |
0.837 |
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| 2017 |
Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, ... ... Nestler EJ, et al. MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications. 8: 15497. PMID 28530238 DOI: 10.1038/Ncomms15497 |
0.779 |
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| 2017 |
Loh YE, Feng J, Nestler E, Shen L. Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data. Bio-Protocol. 7. PMID 28516124 DOI: 10.21769/BioProtoc.2123 |
0.571 |
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| 2017 |
Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K. Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice. Nature Communications. 8: 15142. PMID 28485378 DOI: 10.1038/Ncomms15142 |
0.682 |
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| 2017 |
Hamilton PJ, Burek DJ, Lombroso SI, Neve RL, Robison AJ, Nestler EJ, Heller EA. Cell-Type Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28462942 DOI: 10.1038/Npp.2017.88 |
0.802 |
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| 2017 |
Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Wright KN, Mouzon E, Kabbaj M, Neve R, Turecki G, Shen L, Nestler EJ. Regulation of BAZ1A and Nucleosome Positioning in the Nucleus Accumbens in Response to Cocaine. Neuroscience. PMID 28412501 DOI: 10.1016/J.Neuroscience.2017.04.007 |
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| 2017 |
Han MH, Nestler EJ. Neural Substrates of Depression and Resilience. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28397115 DOI: 10.1007/S13311-017-0527-X |
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| 2017 |
Zhang H, Qian YL, Li C, Liu D, Wang L, Wang XY, Liu MJ, Liu H, Zhang S, Guo XY, Yang JX, Ding HL, Koo JW, Mouzon E, Deisseroth K, ... Nestler EJ, et al. Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain. Biological Psychiatry. PMID 28390647 DOI: 10.1016/J.Biopsych.2017.02.1180 |
0.763 |
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| 2017 |
Zhao JY, Liang L, Gu X, Li Z, Wu S, Sun L, Atianjoh FE, Feng J, Mo K, Jia S, Lutz BM, Bekker A, Nestler EJ, Tao YX. DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons. Nature Communications. 8: 14712. PMID 28270689 DOI: 10.1038/Ncomms14712 |
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| 2017 |
Sun L, Zhao JY, Gu X, Liang L, Wu S, Mo K, Feng J, Guo W, Zhang J, Bekker A, Zhao X, Nestler EJ, Tao YX. Nerve Injury-Induced Epigenetic Silencing Of Opioid Receptors Controlled By Dnmt3a In Primary Afferent Neurons. Pain. PMID 28267064 DOI: 10.1097/J.Pain.0000000000000894 |
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| 2017 |
Ceglia I, Lee KW, Cahill ME, Graves SM, Dietz D, Surmeier DJ, Nestler EJ, Nairn AC, Greengard P, Kim Y. WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115704 DOI: 10.1073/Pnas.1621185114 |
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| 2017 |
Giannarelli C, Rodriguez DT, Zafar MU, Christoffel D, Vialou V, Peña C, Badimon A, Hodes GF, Mury P, Rabkin J, Alique M, Villa G, Argmann C, Nestler EJ, Russo SJ, et al. Susceptibility to chronic social stress increases plaque progression, vulnerability and platelet activation. Thrombosis and Haemostasis. PMID 28078352 DOI: 10.1160/Th16-10-0817 |
0.788 |
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| 2017 |
Feng J, Pena CJ, Purushothaman I, Engmann O, Walker D, Brown AN, Issler O, Doyle M, Harrigan E, Mouzon E, Vialou V, Shen L, Dawlaty MM, Jaenisch R, Nestler EJ. Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28074830 DOI: 10.1038/Npp.2017.6 |
0.835 |
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| 2017 |
Calipari ES, Juarez B, Morel C, Walker DM, Cahill ME, Ribeiro E, Roman-Ortiz C, Ramakrishnan C, Deisseroth K, Han MH, Nestler EJ. Dopaminergic dynamics underlying sex-specific cocaine reward. Nature Communications. 8: 13877. PMID 28072417 DOI: 10.1038/Ncomms13877 |
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| 2017 |
Hodes GE, Walker DM, Labonté B, Nestler EJ, Russo SJ. Understanding the epigenetic basis of sex differences in depression. Journal of Neuroscience Research. 95: 692-702. PMID 27870456 DOI: 10.1002/Jnr.23876 |
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| 2017 |
Nasca C, Bigio B, Cates H, Zelli D, Lau T, Liston C, De Angelis P, Hall B, Issler O, Lee F, Nestler E, McEwen B. mGlu2 as a novel target underling sex-differences in a ventral dentate gyrus (vDG)-medial amygdala (MeA) circuit controlling social behaviour: importance of early life experiences European Neuropsychopharmacology. 27: S608-S609. DOI: 10.1016/S0924-977X(17)31156-2 |
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| 2017 |
Engmann O, Labonte B, Mitchell A, Bashtrykov P, Calipari E, Rosenbluh C, Loh Y, Walker D, Burek D, Hamilton P, Issler O, Neve R, Turecki G, Hurd Y, Chess A, ... ... Nestler E, et al. Cocaine-induced chromatin modifications are associated with increased gene expression and DNA-DNA interactions of autism-candidate 2 European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)31006-4 |
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| 2017 |
Bagot R, Cates H, Purushothaman I, Lorsch Z, Geschwind D, Dong Y, Shen L, Zhang B, Nestler E. 374. Circuit-Wide Transcriptional Profiling Reveals Region Specific Gene Co-Expression Networks Regulating Depression Susceptibility Biological Psychiatry. 81: S153. DOI: 10.1016/J.Biopsych.2017.02.391 |
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| 2017 |
Engmann O, Labonte B, Mitchell A, Bashtrykov P, Calipari E, Rosenbluh C, Loh YE, Walker D, Burek D, Hamilton P, Issler O, Neve R, Turecki G, Chess A, Shen L, ... ... Nestler E, et al. 159. The Largest Number of Cocaine-Induced Changes in Chromatin Modifications Are Associated with Increased Expression and 3D Looping of Auts2 Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.172 |
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| 2017 |
Calipari E, Juarez B, Morel C, Walker D, Cahill M, Ramakrishnan C, Deisseroth K, Han M, Nestler E. 682. Estrous Cycle-Dependent Alterations in Cocaine Affinity at the Dopamine Transporter Underlie Enhanced Cocaine Reward in Females Biological Psychiatry. 81: S276. DOI: 10.1016/J.Biopsych.2017.02.1091 |
0.809 |
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| 2016 |
Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 1: 300-301. PMID 29560862 DOI: 10.1016/J.Bpsc.2016.03.007 |
0.375 |
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| 2016 |
Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, et al. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791098 DOI: 10.1073/Pnas.1608270113 |
0.83 |
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| 2016 |
Torres-Berrío A, Lopez JP, Bagot RC, Nouel D, Dal Bo G, Cuesta S, Zhu L, Manitt C, Eng C, Cooper HM, Storch KF, Turecki G, Nestler EJ, Flores C. DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218. Biological Psychiatry. PMID 27773352 DOI: 10.1016/J.Biopsych.2016.08.017 |
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| 2016 |
Kiraly DD, Walker DM, Calipari ES, Labonte B, Issler O, Pena CJ, Ribeiro EA, Russo SJ, Nestler EJ. Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine. Scientific Reports. 6: 35455. PMID 27752130 DOI: 10.1038/Srep35455 |
0.83 |
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| 2016 |
McHenry JA, Robison CL, Bell GA, Vialou VV, Bolaños-Guzmán CA, Nestler EJ, Hull EM. The role of ΔfosB in the medial preoptic area: Differential effects of mating and cocaine history. Behavioral Neuroscience. 130: 469-78. PMID 27657309 DOI: 10.1037/Bne0000160 |
0.823 |
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| 2016 |
Bagot RC, Cates HM, Purushothaman I, Vialou V, Heller EA, Yieh L, LaBonté B, Peña CJ, Shen L, Wittenberg GM, Nestler EJ. Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles. Biological Psychiatry. PMID 27569543 DOI: 10.1016/J.Biopsych.2016.06.012 |
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| 2016 |
Kim HD, Hesterman J, Call T, Magazu S, Keeley E, Armenta K, Kronman H, Neve RL, Nestler EJ, Ferguson D. SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8441-52. PMID 27511015 DOI: 10.1523/Jneurosci.0212-16.2016 |
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| 2016 |
Damez-Werno DM, Sun H, Scobie KN, Shao N, Rabkin J, Dias C, Calipari ES, Maze I, Pena CJ, Walker DM, Cahill ME, Chandra R, Gancarz A, Mouzon E, Landry JA, ... ... Nestler EJ, et al. Histone arginine methylation in cocaine action in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506785 DOI: 10.1073/Pnas.1605045113 |
0.828 |
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| 2016 |
Wang T, Santos JH, Feng J, Fargo DC, Shen L, Riadi G, Keeley E, Rosh ZS, Nestler EJ, Woychik RP. A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq. Plos One. 11: e0159028. PMID 27415830 DOI: 10.1371/Journal.Pone.0159028 |
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| 2016 |
Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Nestler EJ, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/J.Biopsych.2016.05.004 |
0.751 |
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| 2016 |
Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry. 80: 2-3. PMID 27312230 DOI: 10.1016/J.Biopsych.2016.03.2103 |
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| 2016 |
Graziane NM, Sun S, Wright WJ, Jang D, Liu Z, Huang YH, Nestler EJ, Wang YT, Schlüter OM, Dong Y. Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses. Nature Neuroscience. PMID 27239940 DOI: 10.1038/Nn.4313 |
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| 2016 |
Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, ... ... Nestler EJ, et al. Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility. Neuron. PMID 27181059 DOI: 10.1016/J.Neuron.2016.04.015 |
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| 2016 |
Heller EA, Hamilton PJ, Burek DD, Lombroso SI, Peña CJ, Neve RL, Nestler EJ. Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4690-7. PMID 27122028 DOI: 10.1523/Jneurosci.0013-16.2016 |
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| 2016 |
Ma YY, Wang X, Huang Y, Marie H, Nestler EJ, Schlüter OM, Dong Y. Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091967 DOI: 10.1073/Pnas.1524739113 |
0.42 |
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| 2016 |
Sun H, Martin JA, Werner CT, Wang ZJ, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Gancarz AM, Mouzon EA, Neve RL, Shen L, Dietz DM, ... Nestler EJ, et al. BAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3954-61. PMID 27053203 DOI: 10.1523/Jneurosci.3254-15.2016 |
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| 2016 |
Nestler EJ. Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction? Plos Biology. 14: e1002426. PMID 27015088 DOI: 10.1371/journal.pbio.1002426 |
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| 2016 |
Silverman NS, Popp S, Vialou V, Astafurov K, Nestler EJ, Dow-Edwards D. Effects of Gaboxadol on the Expression of Cocaine Sensitization in Rats. Experimental and Clinical Psychopharmacology. PMID 26901591 DOI: 10.1037/Pha0000069 |
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| 2016 |
Cahill ME, Bagot RC, Gancarz AM, Walker DM, Sun H, Wang ZJ, Heller EA, Feng J, Kennedy PJ, Koo JW, Cates HM, Neve RL, Shen L, Dietz DM, Nestler EJ. Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling. Neuron. 89: 566-82. PMID 26844834 DOI: 10.1016/J.Neuron.2016.01.031 |
0.823 |
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| 2016 |
Calipari ES, Bagot RC, Purushothaman I, Davidson TJ, Yorgason JT, Peña CJ, Walker DM, Pirpinias ST, Guise KG, Ramakrishnan C, Deisseroth K, Nestler EJ. In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831103 DOI: 10.1073/Pnas.1521238113 |
0.82 |
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| 2016 |
Anacker C, Scholz J, O'Donnell KJ, Allemang-Grand R, Diorio J, Bagot RC, Nestler EJ, Hen R, Lerch JP, Meaney MJ. Neuroanatomic Differences Associated With Stress Susceptibility and Resilience. Biological Psychiatry. 79: 840-9. PMID 26422005 DOI: 10.1016/J.Biopsych.2015.08.009 |
0.706 |
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| 2016 |
Maple A, Meyers K, Walker D, Cahill M, Gallitano A, Nikulina E, Nestler E, Hammer R. Ropinirole treatment resulting in recovery of sensorimotor gating induces ΔFosB in mouse nucleus accumbens neurons that co-express D 1 and D 3 dopamine receptors F1000research. 5. DOI: 10.7490/F1000Research.1111948.1 |
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| 2016 |
Labonté B, Maussion G, Yerko, Yang J, Golden S, Suderman M, Navarro L, Checknita D, Gigek C, Lopez J, Neve R, Russo S, Côté G, Meaney M, Mechawar N, ... Nestler E, et al. Speaker 4: Gustavo Turecki, Canada The International Journal of Neuropsychopharmacology. 19: 11-12. DOI: 10.1093/Ijnp/Pyw042.028 |
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| 2015 |
Wook Koo J, Labonté B, Engmann O, Calipari ES, Juarez B, Lorsch Z, Walsh JJ, Friedman AK, Yorgason JT, Han MH, Nestler EJ. Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress-Induced Depressive Behaviors. Biological Psychiatry. PMID 26858215 DOI: 10.1016/J.Biopsych.2015.12.009 |
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| 2015 |
Nestler EJ. Reflections on: "A General Role for Adaptations in G-Proteins and the Cyclic AMP System in Mediating the Chronic Actions of Morphine and Cocaine on Neuronal Function". Brain Research. PMID 26740398 DOI: 10.1016/j.brainres.2015.12.039 |
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| 2015 |
Hodes GE, Pfau ML, Purushothaman I, Ahn HF, Golden SA, Christoffel DJ, Magida J, Brancato A, Takahashi A, Flanigan ME, Ménard C, Aleyasin H, Koo JW, Lorsch ZS, Feng J, ... ... Nestler EJ, et al. Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 16362-76. PMID 26674863 DOI: 10.1523/Jneurosci.1392-15.2015 |
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| 2015 |
Nestler EJ. Role of the Brain's Reward Circuitry in Depression: Transcriptional Mechanisms. International Review of Neurobiology. 124: 151-70. PMID 26472529 DOI: 10.1016/bs.irn.2015.07.003 |
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| 2015 |
Feng J, Wilkinson M, Liu X, Purushothaman I, Ferguson D, Vialou V, Maze I, Shao N, Kennedy P, Koo J, Dias C, Laitman B, Stockman V, LaPlant Q, Cahill ME, ... Nestler EJ, et al. Erratum to: Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens. Genome Biology. 16: 227. PMID 26467768 DOI: 10.1186/S13059-015-0789-8 |
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| 2015 |
Nestler EJ, Peña CJ, Kundakovic M, Mitchell A, Akbarian S. Epigenetic Basis of Mental Illness. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 26450593 DOI: 10.1177/1073858415608147 |
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| 2015 |
Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, ... ... Nestler EJ, et al. ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nature Medicine. PMID 26390241 DOI: 10.1038/Nm.3939 |
0.822 |
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| 2015 |
Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, et al. The role of ventral striatal cAMP signaling in stress-induced behaviors. Nature Neuroscience. 18: 1094-100. PMID 26192746 DOI: 10.1038/Nn.4066 |
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| 2015 |
Khibnik LA, Beaumont M, Doyle M, Heshmati M, Slesinger PA, Nestler EJ, Russo SJ. Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens. Biological Psychiatry. PMID 26164802 DOI: 10.1016/J.Biopsych.2015.05.022 |
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| 2015 |
Vialou V, Thibault M, Kaska S, Cooper S, Gajewski P, Eagle A, Mazei-Robison M, Nestler EJ, Robison AJ. Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress. Neuropharmacology. 99: 28-37. PMID 26164345 DOI: 10.1016/J.Neuropharm.2015.07.005 |
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| 2015 |
Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, ... ... Nestler EJ, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 87: 77-94. PMID 26139371 DOI: 10.1016/J.Neuron.2015.06.014 |
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| 2015 |
Ohnishi YH, Ohnishi YN, Nakamura T, Ohno M, Kennedy PJ, Ohkawa Y, Nishi A, Neve R, Tsuzuki T, Nestler EJ. Correction: PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. Plos One. 10: e0131263. PMID 26110846 DOI: 10.1371/Journal.Pone.0131263 |
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| 2015 |
Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer JF, Deisseroth K, Han MH, Nestler EJ. Corrigendum: Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature Communications. 6: 7626. PMID 26080619 DOI: 10.1038/Ncomms8626 |
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| 2015 |
Wright KN, Hollis F, Duclot F, Dossat AM, Strong CE, Francis TC, Mercer R, Feng J, Dietz DM, Lobo MK, Nestler EJ, Kabbaj M. Methyl Supplementation Attenuates Cocaine-Seeking Behaviors and Cocaine-Induced c-Fos Activation in a DNA Methylation-Dependent Manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8948-58. PMID 26063926 DOI: 10.1523/Jneurosci.5227-14.2015 |
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| 2015 |
Murgatroyd CA, Peña CJ, Podda G, Nestler EJ, Nephew BC. Early life social stress induced changes in depression and anxiety associated neural pathways which are correlated with impaired maternal care. Neuropeptides. PMID 26049556 DOI: 10.1016/J.Npep.2015.05.002 |
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| 2015 |
Li X, Rubio FJ, Zeric T, Bossert JM, Kambhampati S, Cates HM, Kennedy PJ, Liu QR, Cimbro R, Hope BT, Nestler EJ, Shaham Y. Incubation of methamphetamine craving is associated with selective increases in expression of BDNF and trkb, glutamate receptors, and epigenetic enzymes in cue-activated fos-expressing dorsal striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8232-44. PMID 26019338 DOI: 10.1523/Jneurosci.1022-15.2015 |
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| 2015 |
Massart R, Barnea R, Dikshtein Y, Suderman M, Meir O, Hallett M, Kennedy P, Nestler EJ, Szyf M, Yadid G. Role of DNA methylation in the nucleus accumbens in incubation of cocaine craving. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8042-58. PMID 26019323 DOI: 10.1523/Jneurosci.3053-14.2015 |
0.648 |
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| 2015 |
Ohnishi YH, Ohnishi YN, Nakamura T, Ohno M, Kennedy PJ, Yasuyuki O, Nishi A, Neve R, Tsuzuki T, Nestler EJ. PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. Plos One. 10: e0126710. PMID 25962134 DOI: 10.1371/Journal.Pone.0126710 |
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| 2015 |
Dias C, Dietz D, Mazei-Robison M, Sun H, Damez-Werno D, Ferguson D, Wilkinson M, Magida J, Gao V, Neve R, Nestler EJ. Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens. Neuroscience Letters. 598: 23-8. PMID 25957559 DOI: 10.1016/J.Neulet.2015.05.003 |
0.835 |
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| 2015 |
Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer J, Deisseroth K, Han MH, Nestler EJ. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature Communications. 6: 7062. PMID 25952660 DOI: 10.1038/Ncomms8062 |
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| 2015 |
Covington HE, Maze I, Vialou V, Nestler EJ. Antidepressant action of HDAC inhibition in the prefrontal cortex. Neuroscience. 298: 329-35. PMID 25907440 DOI: 10.1016/J.Neuroscience.2015.04.030 |
0.779 |
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| 2015 |
Feng J, Shao N, Szulwach KE, Vialou V, Huynh J, Zhong C, Le T, Ferguson D, Cahill ME, Li Y, Koo JW, Ribeiro E, Labonte B, Laitman BM, Estey D, ... ... Nestler EJ, et al. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature Neuroscience. 18: 536-44. PMID 25774451 DOI: 10.1038/Nn.3976 |
0.837 |
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| 2015 |
Descalzi G, Ikegami D, Ushijima T, Nestler EJ, Zachariou V, Narita M. Epigenetic mechanisms of chronic pain. Trends in Neurosciences. 38: 237-46. PMID 25765319 DOI: 10.1016/J.Tins.2015.02.001 |
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| 2015 |
Ferguson D, Shao N, Heller E, Feng J, Neve R, Kim HD, Call T, Magazu S, Shen L, Nestler EJ. SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3100-11. PMID 25698746 DOI: 10.1523/Jneurosci.4012-14.2015 |
0.815 |
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| 2015 |
Koo JW, Mazei-Robison MS, LaPlant Q, Egervari G, Braunscheidel KM, Adank DN, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno DM, Ribeiro E, Peña CJ, Walker D, Bagot RC, ... ... Nestler EJ, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nature Neuroscience. 18: 415-22. PMID 25643298 DOI: 10.1038/Nn.3932 |
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| 2015 |
Walker DM, Cates HM, Heller EA, Nestler EJ. Regulation of chromatin states by drugs of abuse. Current Opinion in Neurobiology. 30: 112-21. PMID 25486626 DOI: 10.1016/J.Conb.2014.11.002 |
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| 2015 |
Nestler EJ. ∆FosB: a transcriptional regulator of stress and antidepressant responses. European Journal of Pharmacology. 753: 66-72. PMID 25446562 DOI: 10.1016/j.ejphar.2014.10.034 |
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| 2015 |
Ohnishi YN, Ohnishi YH, Vialou V, Mouzon E, LaPlant Q, Nishi A, Nestler EJ. Functional role of the N-terminal domain of ΔFosB in response to stress and drugs of abuse. Neuroscience. 284: 165-70. PMID 25313003 DOI: 10.1016/J.Neuroscience.2014.10.002 |
0.71 |
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| 2015 |
Snyder GL, Vanover KE, Zhu H, Miller DB, O'Callaghan JP, Tomesch J, Li P, Zhang Q, Krishnan V, Hendrick JP, Nestler EJ, Davis RE, Wennogle LP, Mates S. Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission. Psychopharmacology. 232: 605-21. PMID 25120104 DOI: 10.1007/S00213-014-3704-1 |
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| 2015 |
Heller EA, Kaska S, Fallon B, Ferguson D, Kennedy PJ, Neve RL, Nestler EJ, Mazei-Robison MS. Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area. Journal of Neurochemistry. 132: 243-53. PMID 25099208 DOI: 10.1111/Jnc.12925 |
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| 2015 |
Descalzi G, Ikegami D, Ushijima T, Nestler EJ, Zachariou V, Narita M. Erratum: Epigenetic mechanisms of chronic pain Trends in Neurosciences. 38: 579. DOI: 10.1016/J.Tins.2015.07.002 |
0.758 |
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| 2015 |
Vialou V, Thibault M, Kaska S, Cooper S, Gajewski P, Eagle A, Mazei-Robison M, Nestler EJ, Robison AJ. Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress Neuropharmacology. 99: 28-37. DOI: 10.1016/j.neuropharm.2015.07.005 |
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| 2015 |
Zhang Y, Crofton E, Li D, Fan X, Nestler E, Green T. Overexpression of DFosB in rat nucleus accumbens shell mimics environmental enrichment in sucrose self-administration and cocaine seeking Drug and Alcohol Dependence. 146: e31. DOI: 10.1016/J.Drugalcdep.2014.09.764 |
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| 2015 |
Heller E, Cates H, Sun H, Pena CJ, Ferguson D, Knight S, Zhang F, Zhang S, Nestler E. Locus-specific epigenetic reprogramming for the study of reward pathology Drug and Alcohol Dependence. 146: e139-e140. DOI: 10.1016/J.Drugalcdep.2014.09.297 |
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| 2015 |
Khibnik LA, Beaumont M, Doyle M, Heshmati M, Slesinger PA, Nestler EJ, Russo SJ. Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.05.022 |
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Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peña C, ... ... Nestler EJ, et al. β-catenin mediates stress resilience through Dicer1/microRNA regulation. Nature. 516: 51-5. PMID 25383518 DOI: 10.1038/Nature13976 |
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Bagot RC, Labonté B, Peña CJ, Nestler EJ. Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues in Clinical Neuroscience. 16: 281-95. PMID 25364280 |
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Maze I, Shen L, Zhang B, Garcia BA, Shao N, Mitchell A, Sun H, Akbarian S, Allis CD, Nestler EJ. Analytical tools and current challenges in the modern era of neuroepigenomics. Nature Neuroscience. 17: 1476-90. PMID 25349914 DOI: 10.1038/Nn.3816 |
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Heller EA, Cates HM, Peña CJ, Sun H, Shao N, Feng J, Golden SA, Herman JP, Walsh JJ, Mazei-Robison M, Ferguson D, Knight S, Gerber MA, Nievera C, Han MH, ... ... Nestler EJ, et al. Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors. Nature Neuroscience. 17: 1720-7. PMID 25347353 DOI: 10.1038/Nn.3871 |
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Zhang Y, Crofton EJ, Li D, Lobo MK, Fan X, Nestler EJ, Green TA. Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment. Frontiers in Behavioral Neuroscience. 8: 297. PMID 25221490 DOI: 10.3389/Fnbeh.2014.00297 |
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| 2014 |
Feyder M, Södersten E, Santini E, Vialou V, LaPlant Q, Watts EL, Spigolon G, Hansen K, Caboche J, Nestler EJ, Fisone G. A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB Expression. Biological Psychiatry. PMID 25193242 DOI: 10.1016/J.Biopsych.2014.07.019 |
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Cates HM, Thibault M, Pfau M, Heller E, Eagle A, Gajewski P, Bagot R, Colangelo C, Abbott T, Rudenko G, Neve R, Nestler EJ, Robison AJ. Threonine 149 phosphorylation enhances ΔFosB transcriptional activity to control psychomotor responses to cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11461-9. PMID 25143625 DOI: 10.1523/Jneurosci.1611-14.2014 |
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| 2014 |
Lazenka MF, David BG, Lichtman AH, Nestler EJ, Selley DE, Sim-Selley LJ. Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions. Biochemical Pharmacology. 91: 380-9. PMID 25093286 DOI: 10.1016/J.Bcp.2014.07.024 |
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Dong Y, Nestler EJ. The neural rejuvenation hypothesis of cocaine addiction. Trends in Pharmacological Sciences. 35: 374-83. PMID 24958329 DOI: 10.1016/j.tips.2014.05.005 |
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Koo JW, Lobo MK, Chaudhury D, Labonté B, Friedman A, Heller E, Peña CJ, Han MH, Nestler EJ. Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2646-53. PMID 24853771 DOI: 10.1038/Npp.2014.118 |
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Nomaru H, Sakumi K, Katogi A, Ohnishi YN, Kajitani K, Tsuchimoto D, Nestler EJ, Nakabeppu Y. Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia. Glia. 62: 1284-98. PMID 24771617 DOI: 10.1002/glia.22680 |
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Feng J, Wilkinson M, Liu X, Purushothaman I, Ferguson D, Vialou V, Maze I, Shao N, Kennedy P, Koo J, Dias C, Laitman B, Stockman V, LaPlant Q, Cahill ME, ... Nestler EJ, et al. Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens. Genome Biology. 15: R65. PMID 24758366 DOI: 10.1186/Gb-2014-15-4-R65 |
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Mazei-Robison MS, Appasani R, Edwards S, Wee S, Taylor SR, Picciotto MR, Koob GF, Nestler EJ. Self-administration of ethanol, cocaine, or nicotine does not decrease the soma size of ventral tegmental area dopamine neurons. Plos One. 9: e95962. PMID 24755634 DOI: 10.1371/Journal.Pone.0095962 |
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Arango-Lievano M, Schwarz JT, Vernov M, Wilkinson MB, Bradbury K, Feliz A, Marongiu R, Gelfand Y, Warner-Schmidt J, Nestler EJ, Greengard P, Russo SJ, Kaplitt MG. Cell-type specific expression of p11 controls cocaine reward. Biological Psychiatry. 76: 794-801. PMID 24725970 DOI: 10.1016/J.Biopsych.2014.02.012 |
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Peña CJ, Bagot RC, Labonté B, Nestler EJ. Epigenetic signaling in psychiatric disorders. Journal of Molecular Biology. 426: 3389-412. PMID 24709417 DOI: 10.1016/J.Jmb.2014.03.016 |
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Sarkar A, Chachra P, Kennedy P, Pena CJ, Desouza LA, Nestler EJ, Vaidya VA. Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2221-32. PMID 24663010 DOI: 10.1038/Npp.2014.73 |
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Vialou V, Bagot RC, Cahill ME, Ferguson D, Robison AJ, Dietz DM, Fallon B, Mazei-Robison M, Ku SM, Harrigan E, Winstanley CA, Joshi T, Feng J, Berton O, Nestler EJ. Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3878-87. PMID 24623766 DOI: 10.1523/Jneurosci.1787-13.2014 |
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Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, ... ... Nestler EJ, et al. G9a influences neuronal subtype specification in striatum. Nature Neuroscience. 17: 533-9. PMID 24584053 DOI: 10.1038/Nn.3670 |
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Der-Avakian A, Mazei-Robison MS, Kesby JP, Nestler EJ, Markou A. Enduring deficits in brain reward function after chronic social defeat in rats: susceptibility, resilience, and antidepressant response. Biological Psychiatry. 76: 542-9. PMID 24576687 DOI: 10.1016/J.Biopsych.2014.01.013 |
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Nestler EJ. Epigenetic mechanisms of depression. Jama Psychiatry. 71: 454-6. PMID 24499927 DOI: 10.1001/jamapsychiatry.2013.4291 |
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Donahue RJ, Muschamp JW, Russo SJ, Nestler EJ, Carlezon WA. Effects of striatal ΔFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice. Biological Psychiatry. 76: 550-8. PMID 24495460 DOI: 10.1016/J.Biopsych.2013.12.014 |
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Scobie KN, Damez-Werno D, Sun H, Shao N, Gancarz A, Panganiban CH, Dias C, Koo J, Caiafa P, Kaufman L, Neve RL, Dietz DM, Shen L, Nestler EJ. Essential role of poly(ADP-ribosyl)ation in cocaine action. Proceedings of the National Academy of Sciences of the United States of America. 111: 2005-10. PMID 24449909 DOI: 10.1073/Pnas.1319703111 |
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Iñiguez SD, Alcantara LF, Warren BL, Riggs LM, Parise EM, Vialou V, Wright KN, Dayrit G, Nieto SJ, Wilkinson MB, Lobo MK, Neve RL, Nestler EJ, Bolaños-Guzmán CA. Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1007-21. PMID 24431458 DOI: 10.1523/Jneurosci.5725-12.2014 |
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Walsh JJ, Friedman AK, Sun H, Heller EA, Ku SM, Juarez B, Burnham VL, Mazei-Robison MS, Ferguson D, Golden SA, Koo JW, Chaudhury D, Christoffel DJ, Pomeranz L, Friedman JM, ... ... Nestler EJ, et al. Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Nature Neuroscience. 17: 27-9. PMID 24270188 DOI: 10.1038/Nn.3591 |
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Robison AJ, Vialou V, Sun HS, Labonte B, Golden SA, Dias C, Turecki G, Tamminga C, Russo S, Mazei-Robison M, Nestler EJ. Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1178-86. PMID 24240473 DOI: 10.1038/Npp.2013.319 |
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Dietz DM, Kennedy PJ, Sun H, Maze I, Gancarz AM, Vialou V, Koo JW, Mouzon E, Ghose S, Tamminga CA, Nestler EJ. ΔFosB induction in prefrontal cortex by antipsychotic drugs is associated with negative behavioral outcomes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 538-44. PMID 24067299 DOI: 10.1038/Npp.2013.255 |
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Nestler EJ. Epigenetic mechanisms of drug addiction. Neuropharmacology. 76: 259-68. PMID 23643695 DOI: 10.1016/j.neuropharm.2013.04.004 |
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Yadid G, Massart R, Barnea R, Dikhstein Y, Suderman M, Meir O, Hallett M, Kennedy P, Nestler E, Szyf M. P.6.c.016 Dynamic epigenetic landscapes define progression to cocaine addiction European Neuropsychopharmacology. 24: S683-S684. DOI: 10.1016/S0924-977X(14)71102-2 |
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Zhang Y, Li D, Nestler E, Lobo M, Fan X, Green T. A tonic-phasic model of nFOSB action and relevance to environmental enrichment Drug and Alcohol Dependence. 140: e249. DOI: 10.1016/J.Drugalcdep.2014.02.689 |
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Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrío A, Lopez JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, ... ... Nestler EJ, et al. dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. Translational Psychiatry. 3: e338. PMID 24346136 DOI: 10.1038/Tp.2013.105 |
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Lobo MK, Zaman S, Damez-Werno DM, Koo JW, Bagot RC, DiNieri JA, Nugent A, Finkel E, Chaudhury D, Chandra R, Riberio E, Rabkin J, Mouzon E, Cachope R, Cheer JF, ... ... Nestler EJ, et al. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18381-95. PMID 24259563 DOI: 10.1523/Jneurosci.1875-13.2013 |
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Ferguson D, Koo JW, Feng J, Heller E, Rabkin J, Heshmati M, Renthal W, Neve R, Liu X, Shao N, Sartorelli V, Shen L, Nestler EJ. Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16088-98. PMID 24107942 DOI: 10.1523/Jneurosci.1284-13.2013 |
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Lee BR, Ma YY, Huang YH, Wang X, Otaka M, Ishikawa M, Neumann PA, Graziane NM, Brown TE, Suska A, Guo C, Lobo MK, Sesack SR, Wolf ME, Nestler EJ, et al. Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving. Nature Neuroscience. 16: 1644-51. PMID 24077564 DOI: 10.1038/Nn.3533 |
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Russo SJ, Nestler EJ. The brain reward circuitry in mood disorders. Nature Reviews. Neuroscience. 14: 609-25. PMID 23942470 DOI: 10.1038/Nrn3381 |
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Been LE, Hedges VL, Vialou V, Nestler EJ, Meisel RL. ΔJunD overexpression in the nucleus accumbens prevents sexual reward in female Syrian hamsters. Genes, Brain, and Behavior. 12: 666-72. PMID 23790091 DOI: 10.1111/Gbb.12060 |
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Shen L, Shao NY, Liu X, Maze I, Feng J, Nestler EJ. diffReps: detecting differential chromatin modification sites from ChIP-seq data with biological replicates. Plos One. 8: e65598. PMID 23762400 DOI: 10.1371/Journal.Pone.0065598 |
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Nestler EJ. Treating the brain deep down: Brain surgery for anorexia nervosa? Nature Medicine. 19: 678-9. PMID 23744148 DOI: 10.1038/nm.3223 |
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Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling 4 [corrected] is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proceedings of the National Academy of Sciences of the United States of America. 110: 8254-9. PMID 23630294 DOI: 10.1073/Pnas.1214696110 |
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Thanos PK, Robison L, Nestler EJ, Kim R, Michaelides M, Lobo MK, Volkow ND. Mapping brain metabolic connectivity in awake rats with μPET and optogenetic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6343-9. PMID 23575833 DOI: 10.1523/Jneurosci.4997-12.2013 |
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Kurita M, Moreno JL, Holloway T, Kozlenkov A, Mocci G, García-Bea A, Hanks JB, Neve R, Nestler EJ, Russo SJ, González-Maeso J. Repressive epigenetic changes at the mGlu2 promoter in frontal cortex of 5-HT2A knockout mice. Molecular Pharmacology. 83: 1166-75. PMID 23508685 DOI: 10.1124/Mol.112.084582 |
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Kennedy PJ, Feng J, Robison AJ, Maze I, Badimon A, Mouzon E, Chaudhury D, Damez-Werno DM, Haggarty SJ, Han MH, Bassel-Duby R, Olson EN, Nestler EJ. Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation. Nature Neuroscience. 16: 434-40. PMID 23475113 DOI: 10.1038/Nn.3354 |
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Robison AJ, Vialou V, Mazei-Robison M, Feng J, Kourrich S, Collins M, Wee S, Koob G, Turecki G, Neve R, Thomas M, Nestler EJ. Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4295-307. PMID 23467346 DOI: 10.1523/Jneurosci.5192-12.2013 |
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Pitchers KK, Vialou V, Nestler EJ, Laviolette SR, Lehman MN, Coolen LM. Natural and drug rewards act on common neural plasticity mechanisms with ΔFosB as a key mediator. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3434-42. PMID 23426671 DOI: 10.1523/JNEUROSCI.4881-12.2013 |
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Feng J, Nestler EJ. Epigenetic mechanisms of drug addiction. Current Opinion in Neurobiology. 23: 521-8. PMID 23374537 DOI: 10.1016/J.Conb.2013.01.001 |
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Grueter BA, Robison AJ, Neve RL, Nestler EJ, Malenka RC. ∆FosB differentially modulates nucleus accumbens direct and indirect pathway function. Proceedings of the National Academy of Sciences of the United States of America. 110: 1923-8. PMID 23319622 DOI: 10.1073/Pnas.1221742110 |
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Suri D, Veenit V, Sarkar A, Thiagarajan D, Kumar A, Nestler EJ, Galande S, Vaidya VA. Early stress evokes age-dependent biphasic changes in hippocampal neurogenesis, BDNF expression, and cognition. Biological Psychiatry. 73: 658-66. PMID 23237316 DOI: 10.1016/J.Biopsych.2012.10.023 |
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Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, ... ... Nestler EJ, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 493: 532-6. PMID 23235832 DOI: 10.1038/Nature11713 |
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Akbarian S, Nestler EJ. Epigenetic mechanisms in psychiatry. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1-2. PMID 23147478 DOI: 10.1038/npp.2012.185 |
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Vialou V, Feng J, Robison AJ, Nestler EJ. Epigenetic mechanisms of depression and antidepressant action. Annual Review of Pharmacology and Toxicology. 53: 59-87. PMID 23020296 DOI: 10.1146/Annurev-Pharmtox-010611-134540 |
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Warren BL, Vialou VF, Iñiguez SD, Alcantara LF, Wright KN, Feng J, Kennedy PJ, Laplant Q, Shen L, Nestler EJ, Bolaños-Guzmán CA. Neurobiological sequelae of witnessing stressful events in adult mice. Biological Psychiatry. 73: 7-14. PMID 22795644 DOI: 10.1016/J.Biopsych.2012.06.006 |
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Sun H, Kennedy PJ, Nestler EJ. Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 124-37. PMID 22692567 DOI: 10.1038/Npp.2012.73 |
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Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling is a crucial modulator of antidepressant drug action in depression and neuropathic pain models(Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 20 (8254-8259)) Proceedings of the National Academy of Sciences of the United States of America. 110: 11660. DOI: 10.1073/Pnas.1311399110 |
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Meaney MJ, Akbarian S, Nestler EJ, Sweatt JD. Epigenetics. Defining the Frontiers of Genomic Function Epigenetic Regulation in the Nervous System. 341-353. DOI: 10.1016/B978-0-12-391494-1.00014-8 |
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Sun H, Maze I, Dietz DM, Scobie KN, Kennedy PJ, Damez-Werno D, Neve RL, Zachariou V, Shen L, Nestler EJ. Morphine epigenomically regulates behavior through alterations in histone H3 lysine 9 dimethylation in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17454-64. PMID 23197736 DOI: 10.1523/Jneurosci.1357-12.2012 |
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Liu J, Dietz K, DeLoyht JM, Pedre X, Kelkar D, Kaur J, Vialou V, Lobo MK, Dietz DM, Nestler EJ, Dupree J, Casaccia P. Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nature Neuroscience. 15: 1621-3. PMID 23143512 DOI: 10.1038/Nn.3263 |
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Russo SJ, Murrough JW, Han MH, Charney DS, Nestler EJ. Neurobiology of resilience. Nature Neuroscience. 15: 1475-84. PMID 23064380 DOI: 10.1038/Nn.3234 |
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Nestler EJ. Epigenetics: Stress makes its molecular mark. Nature. 490: 171-2. PMID 23060173 DOI: 10.1038/490171a |
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Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, ... ... Nestler EJ, et al. BDNF is a negative modulator of morphine action. Science (New York, N.Y.). 338: 124-8. PMID 23042896 DOI: 10.1126/Science.1222265 |
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Kurita M, Holloway T, García-Bea A, Kozlenkov A, Friedman AK, Moreno JL, Heshmati M, Golden SA, Kennedy PJ, Takahashi N, Dietz DM, Mocci G, Gabilondo AM, Hanks J, Umali A, ... ... Nestler EJ, et al. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nature Neuroscience. 15: 1245-54. PMID 22864611 DOI: 10.1038/Nn.3181 |
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Wang Y, Cesena TI, Ohnishi Y, Burger-Caplan R, Lam V, Kirchhoff PD, Larsen SD, Larsen MJ, Nestler EJ, Rudenko G. Small molecule screening identifies regulators of the transcription factor ΔFosB. Acs Chemical Neuroscience. 3: 546-56. PMID 22860224 DOI: 10.1021/Cn3000235 |
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Damez-Werno D, LaPlant Q, Sun H, Scobie KN, Dietz DM, Walker IM, Koo JW, Vialou VF, Mouzon E, Russo SJ, Nestler EJ. Drug experience epigenetically primes Fosb gene inducibility in rat nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10267-72. PMID 22836260 DOI: 10.1523/Jneurosci.1290-12.2012 |
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Mazei-Robison MS, Nestler EJ. Opiate-induced molecular and cellular plasticity of ventral tegmental area and locus coeruleus catecholamine neurons. Cold Spring Harbor Perspectives in Medicine. 2: a012070. PMID 22762025 DOI: 10.1101/cshperspect.a012070 |
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Tomasiewicz HC, Jacobs MM, Wilkinson MB, Wilson SP, Nestler EJ, Hurd YL. Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability. Biological Psychiatry. 72: 803-10. PMID 22683090 DOI: 10.1016/J.Biopsych.2012.04.026 |
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Nestler EJ, Krystal JH. Planning the new national institute on substance use and addiction disorders. Biological Psychiatry. 72: 166-7. PMID 22683089 DOI: 10.1016/J.Biopsych.2012.05.011 |
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Vialou V, Feng J, Robison AJ, Ku SM, Ferguson D, Scobie KN, Mazei-Robison MS, Mouzon E, Nestler EJ. Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7577-84. PMID 22649236 DOI: 10.1523/Jneurosci.1381-12.2012 |
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| 2012 |
Dumitriu D, Laplant Q, Grossman YS, Dias C, Janssen WG, Russo SJ, Morrison JH, Nestler EJ. Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6957-66. PMID 22593064 DOI: 10.1523/Jneurosci.5718-11.2012 |
0.714 |
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| 2012 |
Dietz DM, Sun H, Lobo MK, Cahill ME, Chadwick B, Gao V, Koo JW, Mazei-Robison MS, Dias C, Maze I, Damez-Werno D, Dietz KC, Scobie KN, Ferguson D, Christoffel D, ... ... Nestler EJ, et al. Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons. Nature Neuroscience. 15: 891-6. PMID 22522400 DOI: 10.1038/Nn.3094 |
0.826 |
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| 2012 |
Rowe GC, Vialou V, Sato K, Saito H, Yin M, Green TA, Lotinun S, Kveiborg M, Horne WC, Nestler EJ, Baron R. Energy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1649-58. PMID 22461201 DOI: 10.1002/Jbmr.1618 |
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| 2012 |
Lobo MK, Nestler EJ, Covington HE. Potential utility of optogenetics in the study of depression. Biological Psychiatry. 71: 1068-74. PMID 22322104 DOI: 10.1016/J.Biopsych.2011.12.026 |
0.604 |
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| 2012 |
Dietz DM, Nestler EJ. From father to offspring: paternal transmission of depressive-like behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 311-2. PMID 22157877 DOI: 10.1038/Npp.2011.167 |
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| 2012 |
Muschamp JW, Nemeth CL, Robison AJ, Nestler EJ, Carlezon WA. ΔFosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid receptor agonist U50488. Biological Psychiatry. 71: 44-50. PMID 21962331 DOI: 10.1016/j.biopsych.2011.08.011 |
0.845 |
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| 2012 |
Miserendino MJ, Guitart X, Terwilliger RZ, Chi S, Nestler EJ. Individual differences in locomotor activity are associated with levels of tyrosine hydroxylase and neurofilament proteins in the ventral tegmental area of sprague-dawley rats. Molecular and Cellular Neurosciences. 4: 440-8. PMID 19912951 DOI: 10.1006/mcne.1993.1055 |
0.347 |
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| 2012 |
Nestler EJ, VanHook AM. Science Signaling Podcast: 9 October 2012 Science Signaling. 5: pc22-pc22. DOI: 10.1126/Scisignal.2003551 |
0.394 |
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| 2012 |
Pittenger C, Nestler EJ, Duman RS. Cyclic Nucleotides in the Nervous System Basic Neurochemistry. 423-441. DOI: 10.1016/B978-0-12-374947-5.00022-5 |
0.508 |
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| 2012 |
Zachariou V, Duman RS, Nestler EJ. G Proteins Basic Neurochemistry. 411-422. DOI: 10.1016/B978-0-12-374947-5.00021-3 |
0.676 |
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| 2011 |
Nestler EJ. Hidden switches in the mind. Scientific American. 305: 76-83. PMID 22214133 DOI: 10.1038/scientificamerican1211-76 |
0.364 |
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| 2011 |
Mazei-Robison MS, Koo JW, Friedman AK, Lansink CS, Robison AJ, Vinish M, Krishnan V, Kim S, Siuta MA, Galli A, Niswender KD, Appasani R, Horvath MC, Neve RL, Worley PF, ... ... Nestler EJ, et al. Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons. Neuron. 72: 977-90. PMID 22196333 DOI: 10.1016/J.Neuron.2011.10.012 |
0.817 |
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| 2011 |
Larson EB, Graham DL, Arzaga RR, Buzin N, Webb J, Green TA, Bass CE, Neve RL, Terwilliger EF, Nestler EJ, Self DW. Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16447-57. PMID 22072694 DOI: 10.1523/Jneurosci.3070-11.2011 |
0.826 |
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| 2011 |
Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/J.1749-6632.2011.06216.X |
0.404 |
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| 2011 |
Robison AJ, Nestler EJ. Transcriptional and epigenetic mechanisms of addiction. Nature Reviews. Neuroscience. 12: 623-37. PMID 21989194 DOI: 10.1038/nrn3111 |
0.712 |
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| 2011 |
Sim-Selley LJ, Cassidy MP, Sparta A, Zachariou V, Nestler EJ, Selley DE. Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens. Neuropharmacology. 61: 1470-6. PMID 21907220 DOI: 10.1016/J.Neuropharm.2011.08.046 |
0.661 |
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| 2011 |
Covington HE, Maze I, Sun H, Bomze HM, DeMaio KD, Wu EY, Dietz DM, Lobo MK, Ghose S, Mouzon E, Neve RL, Tamminga CA, Nestler EJ. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron. 71: 656-70. PMID 21867882 DOI: 10.1016/J.Neuron.2011.06.007 |
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| 2011 |
Lobo MK, Nestler EJ. The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons. Frontiers in Neuroanatomy. 5: 41. PMID 21811439 DOI: 10.3389/fnana.2011.00041 |
0.632 |
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| 2011 |
Wilkinson MB, Dias C, Magida J, Mazei-Robison M, Lobo M, Kennedy P, Dietz D, Covington H, Russo S, Neve R, Ghose S, Tamminga C, Nestler EJ. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9084-92. PMID 21697359 DOI: 10.1523/Jneurosci.0039-11.2011 |
0.832 |
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| 2011 |
Ohnishi YN, Ohnishi YH, Hokama M, Nomaru H, Yamazaki K, Tominaga Y, Sakumi K, Nestler EJ, Nakabeppu Y. FosB is essential for the enhancement of stress tolerance and antagonizes locomotor sensitization by ΔFosB. Biological Psychiatry. 70: 487-95. PMID 21679928 DOI: 10.1016/j.biopsych.2011.04.021 |
0.384 |
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| 2011 |
Dietz DM, Laplant Q, Watts EL, Hodes GE, Russo SJ, Feng J, Oosting RS, Vialou V, Nestler EJ. Paternal transmission of stress-induced pathologies. Biological Psychiatry. 70: 408-14. PMID 21679926 DOI: 10.1016/J.Biopsych.2011.05.005 |
0.809 |
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| 2011 |
Brown TE, Lee BR, Mu P, Ferguson D, Dietz D, Ohnishi YN, Lin Y, Suska A, Ishikawa M, Huang YH, Shen H, Kalivas PW, Sorg BA, Zukin RS, Nestler EJ, et al. A silent synapse-based mechanism for cocaine-induced locomotor sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8163-74. PMID 21632938 DOI: 10.1523/Jneurosci.0016-11.2011 |
0.737 |
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| 2011 |
Lester BM, Tronick E, Nestler E, Abel T, Kosofsky B, Kuzawa CW, Marsit CJ, Maze I, Meaney MJ, Monteggia LM, Reul JM, Skuse DH, Sweatt JD, Wood MA. Behavioral epigenetics. Annals of the New York Academy of Sciences. 1226: 14-33. PMID 21615751 DOI: 10.1111/J.1749-6632.2011.06037.X |
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| 2011 |
Choi KH, Edwards S, Graham DL, Larson EB, Whisler KN, Simmons D, Friedman AK, Walsh JJ, Rahman Z, Monteggia LM, Eisch AJ, Neve RL, Nestler EJ, Han MH, Self DW. Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7927-37. PMID 21613507 DOI: 10.1523/Jneurosci.6014-10.2011 |
0.82 |
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| 2011 |
Knoll AT, Muschamp JW, Sillivan SE, Ferguson D, Dietz DM, Meloni EG, Carroll FI, Nestler EJ, Konradi C, Carlezon WA. Kappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats. Biological Psychiatry. 70: 425-33. PMID 21531393 DOI: 10.1016/J.Biopsych.2011.03.017 |
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| 2011 |
Scott MM, Marcus JN, Pettersen A, Birnbaum SG, Mochizuki T, Scammell TE, Nestler EJ, Elmquist JK, Lutter M. Hcrtr1 and 2 signaling differentially regulates depression-like behaviors. Behavioural Brain Research. 222: 289-94. PMID 21377495 DOI: 10.1016/j.bbr.2011.02.044 |
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| 2011 |
Covington HE, Vialou VF, LaPlant Q, Ohnishi YN, Nestler EJ. Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition. Neuroscience Letters. 493: 122-6. PMID 21335060 DOI: 10.1016/J.Neulet.2011.02.022 |
0.67 |
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| 2011 |
Maze I, Feng J, Wilkinson MB, Sun H, Shen L, Nestler EJ. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 108: 3035-40. PMID 21300862 DOI: 10.1073/Pnas.1015483108 |
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| 2011 |
Maze I, Nestler EJ. The epigenetic landscape of addiction. Annals of the New York Academy of Sciences. 1216: 99-113. PMID 21272014 DOI: 10.1111/J.1749-6632.2010.05893.X |
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| 2011 |
Krishnan V, Nestler EJ. Animal models of depression: molecular perspectives. Current Topics in Behavioral Neurosciences. 7: 121-47. PMID 21225412 DOI: 10.1007/7854_2010_108 |
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| 2011 |
Vialou V, Cui H, Perello M, Mahgoub M, Yu HG, Rush AJ, Pranav H, Jung S, Yangisawa M, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A role for ΔFosB in calorie restriction-induced metabolic changes. Biological Psychiatry. 70: 204-7. PMID 21215388 DOI: 10.1016/J.Biopsych.2010.11.027 |
0.76 |
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| 2011 |
Berger AK, Green T, Siegel SJ, Nestler EJ, Hammer RP. cAMP response element binding protein phosphorylation in nucleus accumbens underlies sustained recovery of sensorimotor gating following repeated D₂-like receptor agonist treatment in rats. Biological Psychiatry. 69: 288-94. PMID 21035786 DOI: 10.1016/J.Biopsych.2010.08.032 |
0.593 |
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| 2011 |
LaPlant Q, Nestler EJ. CRACKing the histone code: cocaine's effects on chromatin structure and function. Hormones and Behavior. 59: 321-30. PMID 20594965 DOI: 10.1016/j.yhbeh.2010.05.015 |
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| 2010 |
Cao JL, Covington HE, Friedman AK, Wilkinson MB, Walsh JJ, Cooper DC, Nestler EJ, Han MH. Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16453-8. PMID 21147984 DOI: 10.1523/Jneurosci.3177-10.2010 |
0.737 |
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| 2010 |
Covington HE, Lobo MK, Maze I, Vialou V, Hyman JM, Zaman S, LaPlant Q, Mouzon E, Ghose S, Tamminga CA, Neve RL, Deisseroth K, Nestler EJ. Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16082-90. PMID 21123555 DOI: 10.1523/Jneurosci.1731-10.2010 |
0.822 |
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| 2010 |
Vialou V, Maze I, Renthal W, LaPlant QC, Watts EL, Mouzon E, Ghose S, Tamminga CA, Nestler EJ. Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14585-92. PMID 20980616 DOI: 10.1523/Jneurosci.2496-10.2010 |
0.852 |
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| 2010 |
Lobo MK, Covington HE, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, ... Nestler EJ, et al. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). 330: 385-90. PMID 20947769 DOI: 10.1126/Science.1188472 |
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| 2010 |
Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nature Neuroscience. 13: 1161-9. PMID 20877280 DOI: 10.1038/Nn.2647 |
0.52 |
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| 2010 |
Krishnan V, Nestler EJ. Linking molecules to mood: new insight into the biology of depression. The American Journal of Psychiatry. 167: 1305-20. PMID 20843874 DOI: 10.1176/Appi.Ajp.2009.10030434 |
0.318 |
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| 2010 |
Cao JL, Vialou VF, Lobo MK, Robison AJ, Neve RL, Cooper DC, Nestler EJ, Han MH. Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 17011-6. PMID 20837544 DOI: 10.1073/pnas.1010077107 |
0.806 |
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| 2010 |
Feng J, Nestler EJ. MeCP2 and drug addiction. Nature Neuroscience. 13: 1039-41. PMID 20740030 DOI: 10.1038/Nn0910-1039 |
0.593 |
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| 2010 |
LaPlant Q, Vialou V, Covington HE, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, ... ... Nestler EJ, et al. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature Neuroscience. 13: 1137-43. PMID 20729844 DOI: 10.1038/Nn.2619 |
0.836 |
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| 2010 |
Bateup HS, Santini E, Shen W, Birnbaum S, Valjent E, Surmeier DJ, Fisone G, Nestler EJ, Greengard P. Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. Proceedings of the National Academy of Sciences of the United States of America. 107: 14845-50. PMID 20682746 DOI: 10.1073/Pnas.1009874107 |
0.77 |
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| 2010 |
Larson EB, Akkentli F, Edwards S, Graham DL, Simmons DL, Alibhai IN, Nestler EJ, Self DW. Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal. Journal of Neurochemistry. 115: 112-22. PMID 20633205 DOI: 10.1111/J.1471-4159.2010.06907.X |
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| 2010 |
Pitchers KK, Frohmader KS, Vialou V, Mouzon E, Nestler EJ, Lehman MN, Coolen LM. ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward. Genes, Brain, and Behavior. 9: 831-40. PMID 20618447 DOI: 10.1111/J.1601-183X.2010.00621.X |
0.628 |
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| 2010 |
Iñiguez SD, Warren BL, Neve RL, Russo SJ, Nestler EJ, Bolaños-Guzmán CA. Viral-mediated expression of extracellular signal-regulated kinase-2 in the ventral tegmental area modulates behavioral responses to cocaine. Behavioural Brain Research. 214: 460-4. PMID 20561901 DOI: 10.1016/J.Bbr.2010.05.040 |
0.829 |
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| 2010 |
Iñiguez SD, Vialou V, Warren BL, Cao JL, Alcantara LF, Davis LC, Manojlovic Z, Neve RL, Russo SJ, Han MH, Nestler EJ, Bolaños-Guzmán CA. Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7652-63. PMID 20519540 DOI: 10.1523/Jneurosci.0951-10.2010 |
0.821 |
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| 2010 |
Vialou V, Robison AJ, Laplant QC, Covington HE, Dietz DM, Ohnishi YN, Mouzon E, Rush AJ, Watts EL, Wallace DL, Iñiguez SD, Ohnishi YH, Steiner MA, Warren BL, Krishnan V, ... ... Nestler EJ, et al. DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nature Neuroscience. 13: 745-52. PMID 20473292 DOI: 10.1038/Nn.2551 |
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| 2010 |
Enwright JF, Wald M, Paddock M, Hoffman E, Arey R, Edwards S, Spencer S, Nestler EJ, McClung CA. DeltaFosB indirectly regulates Cck promoter activity. Brain Research. 1329: 10-20. PMID 20226774 DOI: 10.1016/J.Brainres.2010.02.081 |
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| 2010 |
Russo SJ, Dietz DM, Dumitriu D, Morrison JH, Malenka RC, Nestler EJ. The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends in Neurosciences. 33: 267-76. PMID 20207024 DOI: 10.1016/J.Tins.2010.02.002 |
0.783 |
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| 2010 |
Lagace DC, Donovan MH, DeCarolis NA, Farnbauch LA, Malhotra S, Berton O, Nestler EJ, Krishnan V, Eisch AJ. Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance. Proceedings of the National Academy of Sciences of the United States of America. 107: 4436-41. PMID 20176946 DOI: 10.1073/Pnas.0910072107 |
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| 2010 |
Sun H, Green TA, Theobald DE, Birnbaum SG, Graham DL, Zeeb FD, Nestler EJ, Winstanley CA. Yohimbine increases impulsivity through activation of cAMP response element binding in the orbitofrontal cortex. Biological Psychiatry. 67: 649-56. PMID 20163788 DOI: 10.1016/J.Biopsych.2009.11.030 |
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| 2010 |
Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS. Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 107: 2669-74. PMID 20133768 DOI: 10.1073/Pnas.0910658107 |
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| 2010 |
Liu Y, Aragona BJ, Young KA, Dietz DM, Kabbaj M, Mazei-Robison M, Nestler EJ, Wang Z. Nucleus accumbens dopamine mediates amphetamine-induced impairment of social bonding in a monogamous rodent species. Proceedings of the National Academy of Sciences of the United States of America. 107: 1217-22. PMID 20080553 DOI: 10.1073/Pnas.0911998107 |
0.806 |
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| 2010 |
Chuang JC, Krishnan V, Yu HG, Mason B, Cui H, Cui H, Wilkinson MB, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biological Psychiatry. 67: 1075-82. PMID 20060958 DOI: 10.1016/J.Biopsych.2009.12.003 |
0.66 |
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| 2010 |
Maze I, Covington HE, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, ... ... Nestler EJ, et al. Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (New York, N.Y.). 327: 213-6. PMID 20056891 DOI: 10.1126/Science.1179438 |
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| 2010 |
Covington HE, Vialou V, Nestler EJ. From synapse to nucleus: novel targets for treating depression. Neuropharmacology. 58: 683-93. PMID 20018197 DOI: 10.1016/J.Neuropharm.2009.12.004 |
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| 2010 |
Han MH, Renthal W, Ring RH, Rahman Z, Psifogeorgou K, Howland D, Birnbaum S, Young K, Neve R, Nestler EJ, Zachariou V. Brain region specific actions of regulator of G protein signaling 4 oppose morphine reward and dependence but promote analgesia. Biological Psychiatry. 67: 761-9. PMID 19914603 DOI: 10.1016/J.Biopsych.2009.08.041 |
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| 2010 |
Green TA, Alibhai IN, Roybal CN, Winstanley CA, Theobald DE, Birnbaum SG, Graham AR, Unterberg S, Graham DL, Vialou V, Bass CE, Terwilliger EF, Bardo MT, Nestler EJ. Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens. Biological Psychiatry. 67: 28-35. PMID 19709647 DOI: 10.1016/J.Biopsych.2009.06.022 |
0.823 |
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| 2010 |
Eisch A, Lagace D, Donovan M, DeCarolis N, Farnbauch L, Malhotra S, Berton O, Nestler E, Krishnan V. S.08.05 New findings on the neurobiology of resilience and susceptibility to social stress European Neuropsychopharmacology. 20: S176. DOI: 10.1016/S0924-977X(10)70157-7 |
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| 2010 |
Kumar A, Green TA, Russo SJ, Renthal W, Nestler EJ. Transcription and Reward Systems Encyclopedia of Neuroscience. 1063-1070. DOI: 10.1016/B978-008045046-9.00195-9 |
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| 2009 |
Wang H, Westin L, Nong Y, Birnbaum S, Bendor J, Brismar H, Nestler E, Aperia A, Flajolet M, Greengard P. Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling. Science (New York, N.Y.). 326: 1554-7. PMID 20007903 DOI: 10.1126/science.1178496 |
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| 2009 |
Renthal W, Nestler EJ. Chromatin regulation in drug addiction and depression. Dialogues in Clinical Neuroscience. 11: 257-68. PMID 19877494 |
0.716 |
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| 2009 |
Covington HE, Maze I, LaPlant QC, Vialou VF, Ohnishi YN, Berton O, Fass DM, Renthal W, Rush AJ, Wu EY, Ghose S, Krishnan V, Russo SJ, Tamminga C, Haggarty SJ, ... Nestler EJ, et al. Antidepressant actions of histone deacetylase inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11451-60. PMID 19759294 DOI: 10.1523/Jneurosci.1758-09.2009 |
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| 2009 |
Renthal W, Nestler EJ. Histone acetylation in drug addiction. Seminars in Cell & Developmental Biology. 20: 387-94. PMID 19560043 DOI: 10.1016/j.semcdb.2009.01.005 |
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| 2009 |
Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, Sikder D, Kodadek TJ, Nestler EJ. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7820-32. PMID 19535594 DOI: 10.1523/Jneurosci.0932-09.2009 |
0.826 |
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| 2009 |
Watanabe H, Henriksson R, Ohnishi YN, Ohnishi YH, Harper C, Sheedy D, Garrick T, Nyberg F, Nestler EJ, Bakalkin G, Yakovleva T. FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics. Addiction Biology. 14: 294-7. PMID 19523044 DOI: 10.1111/j.1369-1600.2009.00155.x |
0.319 |
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| 2009 |
Berton O, Guigoni C, Li Q, Bioulac BH, Aubert I, Gross CE, Dileone RJ, Nestler EJ, Bezard E. Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease. Biological Psychiatry. 66: 554-61. PMID 19481198 DOI: 10.1016/J.Biopsych.2009.04.005 |
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| 2009 |
Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nature Reviews. Neuroscience. 10: 446-57. PMID 19455174 DOI: 10.1038/Nrn2649 |
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| 2009 |
Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, ... ... Nestler EJ, et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron. 62: 335-48. PMID 19447090 DOI: 10.1016/J.Neuron.2009.03.026 |
0.84 |
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| 2009 |
Dietz DM, Dietz KC, Nestler EJ, Russo SJ. Molecular mechanisms of psychostimulant-induced structural plasticity. Pharmacopsychiatry. 42: S69-78. PMID 19434558 DOI: 10.1055/S-0029-1202847 |
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| 2009 |
Nestler EJ. Effects of drugs of abuse on the brain during development. Foreword. Developmental Neuroscience. 31: 6. PMID 19372682 DOI: 10.1159/000209398 |
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| 2009 |
Freet CS, Steffen C, Nestler EJ, Grigson PS. Overexpression of DeltaFosB is associated with attenuated cocaine-induced suppression of saccharin intake in mice. Behavioral Neuroscience. 123: 397-407. PMID 19331462 DOI: 10.1037/A0015033 |
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| 2009 |
Russo SJ, Wilkinson MB, Mazei-Robison MS, Dietz DM, Maze I, Krishnan V, Renthal W, Graham A, Birnbaum SG, Green TA, Robison B, Lesselyong A, Perrotti LI, Bolaños CA, Kumar A, ... ... Nestler EJ, et al. Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3529-37. PMID 19295158 DOI: 10.1523/Jneurosci.6173-08.2009 |
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| 2009 |
LaPlant Q, Chakravarty S, Vialou V, Mukherjee S, Koo JW, Kalahasti G, Bradbury KR, Taylor SV, Maze I, Kumar A, Graham A, Birnbaum SG, Krishnan V, Truong HT, Neve RL, ... Nestler EJ, et al. Role of nuclear factor kappaB in ovarian hormone-mediated stress hypersensitivity in female mice. Biological Psychiatry. 65: 874-80. PMID 19251249 DOI: 10.1016/J.Biopsych.2009.01.024 |
0.821 |
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| 2009 |
Dinieri JA, Nemeth CL, Parsegian A, Carle T, Gurevich VV, Gurevich E, Neve RL, Nestler EJ, Carlezon WA. Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1855-9. PMID 19211892 DOI: 10.1523/Jneurosci.5104-08.2009 |
0.651 |
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| 2009 |
Lutter M, Nestler EJ. Homeostatic and hedonic signals interact in the regulation of food intake. The Journal of Nutrition. 139: 629-32. PMID 19176746 DOI: 10.3945/jn.108.097618 |
0.307 |
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| 2009 |
Wallace DL, Han MH, Graham DL, Green TA, Vialou V, Iñiguez SD, Cao JL, Kirk A, Chakravarty S, Kumar A, Krishnan V, Neve RL, Cooper DC, Bolaños CA, Barrot M, ... ... Nestler EJ, et al. CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits. Nature Neuroscience. 12: 200-9. PMID 19151710 DOI: 10.1038/Nn.2257 |
0.811 |
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| 2009 |
Winstanley CA, Green TA, Theobald DE, Renthal W, LaPlant Q, DiLeone RJ, Chakravarty S, Nestler EJ. DeltaFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine. Pharmacology, Biochemistry, and Behavior. 93: 278-84. PMID 19135469 DOI: 10.1016/J.Pbb.2008.12.007 |
0.835 |
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| 2009 |
Rogge GA, Jones DC, Green T, Nestler E, Kuhar MJ. Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo. Brain Research. 1251: 42-52. PMID 19046951 DOI: 10.1016/J.Brainres.2008.11.011 |
0.623 |
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| 2009 |
Ulery-Reynolds PG, Castillo MA, Vialou V, Russo SJ, Nestler EJ. Phosphorylation of DeltaFosB mediates its stability in vivo. Neuroscience. 158: 369-72. PMID 19041372 DOI: 10.1016/J.Neuroscience.2008.10.059 |
0.78 |
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| 2009 |
Graham DL, Krishnan V, Larson EB, Graham A, Edwards S, Bachtell RK, Simmons D, Gent LM, Berton O, Bolanos CA, DiLeone RJ, Parada LF, Nestler EJ, Self DW. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biological Psychiatry. 65: 696-701. PMID 18990365 DOI: 10.1016/J.Biopsych.2008.09.032 |
0.828 |
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| 2009 |
Russo SJ, Mazei-Robison MS, Ables JL, Nestler EJ. Neurotrophic factors and structural plasticity in addiction. Neuropharmacology. 56: 73-82. PMID 18647613 DOI: 10.1016/J.Neuropharm.2008.06.059 |
0.817 |
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| 2009 |
Winstanley CA, Bachtell RK, Theobald DE, Laali S, Green TA, Kumar A, Chakravarty S, Self DW, Nestler EJ. Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 19: 435-44. PMID 18539927 DOI: 10.1093/Cercor/Bhn094 |
0.82 |
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| 2009 |
Hedges VL, Chakravarty S, Nestler EJ, Meisel RL. Erratum: δ FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters (Genes, Brain and Behavior (2009) DOI: 10.1111/j.1601-183X.2009.00491.x) Genes, Brain and Behavior. 8. DOI: 10.1111/J.1601-183X.2009.00517.X |
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| 2008 |
Borrelli E, Nestler EJ, Allis CD, Sassone-Corsi P. Decoding the epigenetic language of neuronal plasticity. Neuron. 60: 961-74. PMID 19109904 DOI: 10.1016/J.Neuron.2008.10.012 |
0.538 |
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| 2008 |
Jiang Y, Langley B, Lubin FD, Renthal W, Wood MA, Yasui DH, Kumar A, Nestler EJ, Akbarian S, Beckel-Mitchener AC. Epigenetics in the nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11753-9. PMID 19005036 DOI: 10.1523/Jneurosci.3797-08.2008 |
0.715 |
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| 2008 |
Krishnan V, Nestler EJ. The molecular neurobiology of depression. Nature. 455: 894-902. PMID 18923511 DOI: 10.1038/Nature07455 |
0.322 |
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| 2008 |
Wallace DL, Vialou V, Rios L, Carle-Florence TL, Chakravarty S, Kumar A, Graham DL, Green TA, Kirk A, Iñiguez SD, Perrotti LI, Barrot M, DiLeone RJ, Nestler EJ, Bolaños-Guzmán CA. The influence of DeltaFosB in the nucleus accumbens on natural reward-related behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10272-7. PMID 18842886 DOI: 10.1523/Jneurosci.1531-08.2008 |
0.819 |
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| 2008 |
Iñiguez SD, Warren BL, Neve RL, Nestler EJ, Russo SJ, Bolaños-Guzmán CA. Insulin receptor substrate-2 in the ventral tegmental area regulates behavioral responses to cocaine. Behavioral Neuroscience. 122: 1172-7. PMID 18823173 DOI: 10.1037/A0012893 |
0.83 |
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| 2008 |
Krishnan V, Berton O, Nestler E. The use of animal models in psychiatric research and treatment. The American Journal of Psychiatry. 165: 1109. PMID 18765492 DOI: 10.1176/Appi.Ajp.2008.08071076 |
0.62 |
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| 2008 |
Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. 59: 621-33. PMID 18760698 DOI: 10.1016/J.Neuron.2008.06.020 |
0.828 |
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| 2008 |
Kim KS, Lee KW, Baek IS, Lim CM, Krishnan V, Lee JK, Nestler EJ, Han PL. Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. Journal of Neurochemistry. 107: 105-15. PMID 18673448 DOI: 10.1111/J.1471-4159.2008.05592.X |
0.383 |
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| 2008 |
Teegarden SL, Nestler EJ, Bale TL. Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biological Psychiatry. 64: 941-50. PMID 18657800 DOI: 10.1016/J.Biopsych.2008.06.007 |
0.391 |
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| 2008 |
Nestler EJ. Review. Transcriptional mechanisms of addiction: role of DeltaFosB. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3245-55. PMID 18640924 DOI: 10.1098/rstb.2008.0067 |
0.415 |
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| 2008 |
Krishnan V, Han MH, Mazei-Robison M, Iñiguez SD, Ables JL, Vialou V, Berton O, Ghose S, Covington HE, Wiley MD, Henderson RP, Neve RL, Eisch AJ, Tamminga CA, Russo SJ, ... ... Nestler EJ, et al. AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biological Psychiatry. 64: 691-700. PMID 18639865 DOI: 10.1016/J.Biopsych.2008.06.003 |
0.825 |
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| 2008 |
Renthal W, Nestler EJ. Epigenetic mechanisms in drug addiction. Trends in Molecular Medicine. 14: 341-50. PMID 18635399 DOI: 10.1016/j.molmed.2008.06.004 |
0.722 |
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| 2008 |
Renthal W, Carle TL, Maze I, Covington HE, Truong HT, Alibhai I, Kumar A, Montgomery RL, Olson EN, Nestler EJ. Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7344-9. PMID 18632938 DOI: 10.1523/Jneurosci.1043-08.2008 |
0.823 |
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| 2008 |
Lutter M, Sakata I, Osborne-Lawrence S, Rovinsky SA, Anderson JG, Jung S, Birnbaum S, Yanagisawa M, Elmquist JK, Nestler EJ, Zigman JM. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nature Neuroscience. 11: 752-3. PMID 18552842 DOI: 10.1038/Nn.2139 |
0.362 |
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| 2008 |
Krishnan V, Graham A, Mazei-Robison MS, Lagace DC, Kim KS, Birnbaum S, Eisch AJ, Han PL, Storm DR, Zachariou V, Nestler EJ. Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting. Biological Psychiatry. 64: 336-43. PMID 18468583 DOI: 10.1016/J.Biopsych.2008.03.026 |
0.805 |
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| 2008 |
Charlton JJ, Allen PB, Psifogeorgou K, Chakravarty S, Gomes I, Neve RL, Devi LA, Greengard P, Nestler EJ, Zachariou V. Multiple actions of spinophilin regulate mu opioid receptor function. Neuron. 58: 238-47. PMID 18439408 DOI: 10.1016/J.Neuron.2008.02.006 |
0.689 |
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| 2008 |
Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005 |
0.752 |
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| 2008 |
Lutter M, Krishnan V, Russo SJ, Jung S, McClung CA, Nestler EJ. Orexin signaling mediates the antidepressant-like effect of calorie restriction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3071-5. PMID 18354010 DOI: 10.1523/Jneurosci.5584-07.2008 |
0.801 |
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| 2008 |
Green TA, Alibhai IN, Unterberg S, Neve RL, Ghose S, Tamminga CA, Nestler EJ. Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2025-32. PMID 18305237 DOI: 10.1523/Jneurosci.5273-07.2008 |
0.655 |
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| 2008 |
Perrotti LI, Weaver RR, Robison B, Renthal W, Maze I, Yazdani S, Elmore RG, Knapp DJ, Selley DE, Martin BR, Sim-Selley L, Bachtell RK, Self DW, Nestler EJ. Distinct patterns of DeltaFosB induction in brain by drugs of abuse. Synapse (New York, N.Y.). 62: 358-69. PMID 18293355 DOI: 10.1002/Syn.20500 |
0.82 |
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| 2008 |
Zachariou V, Liu R, LaPlant Q, Xiao G, Renthal W, Chan GC, Storm DR, Aghajanian G, Nestler EJ. Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies. Biological Psychiatry. 63: 1013-21. PMID 18222416 DOI: 10.1016/J.Biopsych.2007.11.021 |
0.793 |
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| 2008 |
Potenza MN, Brodkin ES, Yang BZ, Birnbaum SG, Nestler EJ, Gelernter J. Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2735-46. PMID 18216777 DOI: 10.1038/Sj.Npp.1301667 |
0.317 |
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| 2008 |
Huang YH, Lin Y, Brown TE, Han MH, Saal DB, Neve RL, Zukin RS, Sorg BA, Nestler EJ, Malenka RC, Dong Y. CREB modulates the functional output of nucleus accumbens neurons: a critical role of N-methyl-D-aspartate glutamate receptor (NMDAR) receptors. The Journal of Biological Chemistry. 283: 2751-60. PMID 18055458 DOI: 10.1074/Jbc.M706578200 |
0.55 |
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| 2008 |
Steiner MA, Marsicano G, Nestler EJ, Holsboer F, Lutz B, Wotjak CT. Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. Psychoneuroendocrinology. 33: 54-67. PMID 17976922 DOI: 10.1016/J.Psyneuen.2007.09.008 |
0.388 |
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| 2008 |
McClung CA, Nestler EJ. Neuroplasticity mediated by altered gene expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3-17. PMID 17728700 DOI: 10.1038/Sj.Npp.1301544 |
0.678 |
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| 2008 |
Borgkvist A, Nestler E, Greengard P, Fisone G, Brené S. P.1.05 Involvement of DARPP-32, FosB, and dynorphin in voluntary wheel running European Neuropsychopharmacology. 18: s5-s6. DOI: 10.1016/S0924-977X(08)70006-3 |
0.388 |
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| 2007 |
Renthal W, Maze I, Krishnan V, Covington HE, Xiao G, Kumar A, Russo SJ, Graham A, Tsankova N, Kippin TE, Kerstetter KA, Neve RL, Haggarty SJ, McKinsey TA, Bassel-Duby R, ... ... Nestler EJ, et al. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron. 56: 517-29. PMID 17988634 DOI: 10.1016/J.Neuron.2007.09.032 |
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| 2007 |
Krishnan V, Han MH, Graham DL, Berton O, Renthal W, Russo SJ, Laplant Q, Graham A, Lutter M, Lagace DC, Ghose S, Reister R, Tannous P, Green TA, Neve RL, ... ... Nestler EJ, et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell. 131: 391-404. PMID 17956738 DOI: 10.1016/J.Cell.2007.09.018 |
0.812 |
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| 2007 |
Winstanley CA, LaPlant Q, Theobald DE, Green TA, Bachtell RK, Perrotti LI, DiLeone RJ, Russo SJ, Garth WJ, Self DW, Nestler EJ. DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10497-507. PMID 17898221 DOI: 10.1523/Jneurosci.2566-07.2007 |
0.823 |
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| 2007 |
Berton O, Covington HE, Ebner K, Tsankova NM, Carle TL, Ulery P, Bhonsle A, Barrot M, Krishnan V, Singewald GM, Singewald N, Birnbaum S, Neve RL, Nestler EJ. Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron. 55: 289-300. PMID 17640529 DOI: 10.1016/J.Neuron.2007.06.033 |
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| 2007 |
Jorissen HJ, Ulery PG, Henry L, Gourneni S, Nestler EJ, Rudenko G. Dimerization and DNA-binding properties of the transcription factor DeltaFosB. Biochemistry. 46: 8360-72. PMID 17580968 DOI: 10.1021/bi700494v |
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| 2007 |
Carle TL, Ohnishi YN, Ohnishi YH, Alibhai IN, Wilkinson MB, Kumar A, Nestler EJ. Proteasome-dependent and -independent mechanisms for FosB destabilization: identification of FosB degron domains and implications for DeltaFosB stability. The European Journal of Neuroscience. 25: 3009-19. PMID 17561814 DOI: 10.1111/J.1460-9568.2007.05575.X |
0.689 |
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| 2007 |
Wolf DH, Nestler EJ, Russell DS. Regulation of neuronal PLCgamma by chronic morphine. Brain Research. 1156: 9-20. PMID 17524370 DOI: 10.1016/J.Brainres.2007.04.059 |
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| 2007 |
Tsankova N, Renthal W, Kumar A, Nestler EJ. Epigenetic regulation in psychiatric disorders. Nature Reviews. Neuroscience. 8: 355-67. PMID 17453016 DOI: 10.1038/Nrn2132 |
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| 2007 |
Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA, et al. Mania-like behavior induced by disruption of CLOCK. Proceedings of the National Academy of Sciences of the United States of America. 104: 6406-11. PMID 17379666 DOI: 10.1073/Pnas.0609625104 |
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| 2007 |
Taylor JR, Lynch WJ, Sanchez H, Olausson P, Nestler EJ, Bibb JA. Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. 104: 4147-52. PMID 17360491 DOI: 10.1073/pnas.0610288104 |
0.69 |
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| 2007 |
Alibhai IN, Green TA, Potashkin JA, Nestler EJ. Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies. Brain Research. 1143: 22-33. PMID 17324382 DOI: 10.1016/J.Brainres.2007.01.069 |
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| 2007 |
Ulery PG, Nestler EJ. Regulation of DeltaFosB transcriptional activity by Ser27 phosphorylation. The European Journal of Neuroscience. 25: 224-30. PMID 17241283 DOI: 10.1111/j.1460-9568.2006.05262.x |
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| 2007 |
Russo SJ, Bolanos CA, Theobald DE, DeCarolis NA, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve RL, Eisch AJ, Nestler EJ. IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nature Neuroscience. 10: 93-9. PMID 17143271 DOI: 10.1038/Nn1812 |
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| 2007 |
Olson VG, Green TA, Neve RL, Nestler EJ. Regulation of morphine reward and feeding by CREB in the lateral hypothalamus. Synapse (New York, N.Y.). 61: 110-3. PMID 17117424 DOI: 10.1002/Syn.20344 |
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| 2007 |
Olson VG, Nestler EJ. Topographical organization of GABAergic neurons within the ventral tegmental area of the rat. Synapse (New York, N.Y.). 61: 87-95. PMID 17117419 DOI: 10.1002/Syn.20345 |
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| 2007 |
Monteggia LM, Luikart B, Barrot M, Theobold D, Malkovska I, Nef S, Parada LF, Nestler EJ. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biological Psychiatry. 61: 187-97. PMID 16697351 DOI: 10.1016/J.Biopsych.2006.03.021 |
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| 2007 |
Steiner M, Marsicano G, Nestler E, Holsboer F, Lutz B, Wotjak C. Endocannabinoid signaling modulates HPA axis activity in the mouse – implications for depression disorders Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991731 |
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| 2007 |
Bezard E, Berton O, Guigoni C, Dovero S, Kumar A, McClung C, DiLeone R, Nestler E. 2.501 Role of DeltaFosB in the development of L-DOPA-induced dyskinesia in a non-human primate model of Parkinson's disease Parkinsonism & Related Disorders. 13: S142. DOI: 10.1016/S1353-8020(08)70775-2 |
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| 2007 |
Papachatzaki MM, Han MH, Ring R, Rahman Z, Nestler EJ, Zachariou V. S.16.04 An essential role of RGS proteins in opiate addiction European Neuropsychopharmacology. 17. DOI: 10.1016/S0924-977X(07)70236-5 |
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| 2007 |
Berton O, Covington HE, Ebner K, Tsankova NM, Carle TL, Ulery P, Bhonsle A, Barrot M, Krishnan V, Singewald GM, Singewald N, Birnbaum S, Neve RL, Nestler EJ. Induction of ΔFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses (DOI:10.1016/j.neuron.2007.06.033) Neuron. 56: 574. DOI: 10.1016/J.Neuron.2007.10.028 |
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| 2006 |
Olausson P, Jentsch JD, Tronson N, Neve RL, Nestler EJ, Taylor JR. DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9196-204. PMID 16957076 DOI: 10.1523/JNEUROSCI.1124-06.2006 |
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| 2006 |
Green TA, Alibhai IN, Hommel JD, DiLeone RJ, Kumar A, Theobald DE, Neve RL, Nestler EJ. Induction of inducible cAMP early repressor expression in nucleus accumbens by stress or amphetamine increases behavioral responses to emotional stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8235-42. PMID 16899718 DOI: 10.1523/Jneurosci.0880-06.2006 |
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| 2006 |
Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction: the role of reward-related learning and memory. Annual Review of Neuroscience. 29: 565-98. PMID 16776597 DOI: 10.1146/Annurev.Neuro.29.051605.113009 |
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Ulery PG, Rudenko G, Nestler EJ. Regulation of DeltaFosB stability by phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5131-42. PMID 16687504 DOI: 10.1523/JNEUROSCI.4970-05.2006 |
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| 2006 |
Han MH, Bolaños CA, Green TA, Olson VG, Neve RL, Liu RJ, Aghajanian GK, Nestler EJ. Role of cAMP response element-binding protein in the rat locus ceruleus: regulation of neuronal activity and opiate withdrawal behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4624-9. PMID 16641242 DOI: 10.1523/Jneurosci.4701-05.2006 |
0.811 |
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| 2006 |
Allen PB, Zachariou V, Svenningsson P, Lepore AC, Centonze D, Costa C, Rossi S, Bender G, Chen G, Feng J, Snyder GL, Bernardi G, Nestler EJ, Yan Z, Calabresi P, et al. Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity. Neuroscience. 140: 897-911. PMID 16600521 DOI: 10.1016/J.Neuroscience.2006.02.067 |
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| 2006 |
Nestler EJ, Carlezon WA. The mesolimbic dopamine reward circuit in depression. Biological Psychiatry. 59: 1151-9. PMID 16566899 DOI: 10.1016/j.biopsych.2005.09.018 |
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| 2006 |
Kim KS, Lee KW, Lee KW, Im JY, Yoo JY, Kim SW, Lee JK, Nestler EJ, Han PL. Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action. Proceedings of the National Academy of Sciences of the United States of America. 103: 3908-13. PMID 16537460 DOI: 10.1073/pnas.0508812103 |
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| 2006 |
Dong Y, Green T, Saal D, Marie H, Neve R, Nestler EJ, Malenka RC. CREB modulates excitability of nucleus accumbens neurons. Nature Neuroscience. 9: 475-7. PMID 16520736 DOI: 10.1038/Nn1661 |
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| 2006 |
Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nature Neuroscience. 9: 519-25. PMID 16501568 DOI: 10.1038/Nn1659 |
0.822 |
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| 2006 |
Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science (New York, N.Y.). 311: 864-8. PMID 16469931 DOI: 10.1126/Science.1120972 |
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| 2006 |
Berton O, Nestler EJ. New approaches to antidepressant drug discovery: beyond monoamines. Nature Reviews. Neuroscience. 7: 137-51. PMID 16429123 DOI: 10.1038/Nrn1846 |
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| 2006 |
Zachariou V, Bolanos CA, Selley DE, Theobald D, Cassidy MP, Kelz MB, Shaw-Lutchman T, Berton O, Sim-Selley LJ, Dileone RJ, Kumar A, Nestler EJ. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature Neuroscience. 9: 205-11. PMID 16415864 DOI: 10.1038/Nn1636 |
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| 2006 |
Zachariou V, Sgambato-Faure V, Sasaki T, Svenningsson P, Berton O, Fienberg AA, Nairn AC, Greengard P, Nestler EJ. Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 555-62. PMID 16123776 DOI: 10.1038/Sj.Npp.1300832 |
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| 2006 |
Green TA, Nestler EJ. Psychiatric Applications of Viral Vectors Gene Therapy of the Central Nervous System: From Bench to Bedside. 181-193. DOI: 10.1016/B978-012397632-1/50015-0 |
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Nestler EJ, Chao J. Disorders of substance abuse and dependence Principles of Molecular Medicine. 1220-1227. DOI: 10.1007/978-1-59259-963-9_129 |
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| 2005 |
Colvis CM, Pollock JD, Goodman RH, Impey S, Dunn J, Mandel G, Champagne FA, Mayford M, Korzus E, Kumar A, Renthal W, Theobald DE, Nestler EJ. Epigenetic mechanisms and gene networks in the nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10379-89. PMID 16280577 DOI: 10.1523/Jneurosci.4119-05.2005 |
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| 2005 |
Nestler EJ. Is there a common molecular pathway for addiction? Nature Neuroscience. 8: 1445-9. PMID 16251986 DOI: 10.1038/nn1578 |
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| 2005 |
Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, Laplant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ. Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron. 48: 303-14. PMID 16242410 DOI: 10.1016/J.Neuron.2005.09.023 |
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| 2005 |
Neve RL, Neve KA, Nestler EJ, Carlezon WA. Use of herpes virus amplicon vectors to study brain disorders. Biotechniques. 39: 381-91. PMID 16206910 DOI: 10.2144/05393Ps01 |
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| 2005 |
Carlezon WA, Duman RS, Nestler EJ. The many faces of CREB. Trends in Neurosciences. 28: 436-45. PMID 15982754 DOI: 10.1016/j.tins.2005.06.005 |
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| 2005 |
McClung CA, Nestler EJ, Zachariou V. Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6005-15. PMID 15976090 DOI: 10.1523/Jneurosci.0062-05.2005 |
0.777 |
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| 2005 |
McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ. Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proceedings of the National Academy of Sciences of the United States of America. 102: 9377-81. PMID 15967985 DOI: 10.1073/Pnas.0503584102 |
0.695 |
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| 2005 |
Olson VG, Zabetian CP, Bolanos CA, Edwards S, Barrot M, Eisch AJ, Hughes T, Self DW, Neve RL, Nestler EJ. Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5553-62. PMID 15944383 DOI: 10.1523/Jneurosci.0345-05.2005 |
0.828 |
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| 2005 |
Perrotti LI, Bolaños CA, Choi KH, Russo SJ, Edwards S, Ulery PG, Wallace DL, Self DW, Nestler EJ, Barrot M. DeltaFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment. The European Journal of Neuroscience. 21: 2817-24. PMID 15926929 DOI: 10.1111/J.1460-9568.2005.04110.X |
0.836 |
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| 2005 |
Barrot M, Wallace DL, Bolaños CA, Graham DL, Perrotti LI, Neve RL, Chambliss H, Yin JC, Nestler EJ. Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 102: 8357-62. PMID 15923261 DOI: 10.1073/Pnas.0500587102 |
0.809 |
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| 2005 |
Hsu R, Taylor JR, Newton SS, Alvaro JD, Haile C, Han G, Hruby VJ, Nestler EJ, Duman RS. Blockade of melanocortin transmission inhibits cocaine reward. The European Journal of Neuroscience. 21: 2233-42. PMID 15869520 DOI: 10.1111/J.1460-9568.2005.04038.X |
0.69 |
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| 2005 |
Georgescu D, Sears RM, Hommel JD, Barrot M, Bolaños CA, Marsh DJ, Bednarek MA, Bibb JA, Maratos-Flier E, Nestler EJ, DiLeone RJ. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2933-40. PMID 15772353 DOI: 10.1523/Jneurosci.1714-04.2005 |
0.816 |
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| 2005 |
Bolaños CA, Neve RL, Nestler EJ. Phospholipase C gamma in distinct regions of the ventral tegmental area differentially regulates morphine-induced locomotor activity. Synapse (New York, N.Y.). 56: 166-9. PMID 15765533 DOI: 10.1002/syn.20136 |
0.386 |
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| 2005 |
Green T, Neve R, Alibhai I, Nestler E. O11 ICER OVEREXPRESSION IN THE NUCLEUS ACCUMBENS INCREASES BEHAVIORAL RESPONSES TO AMPHETAMINE Behavioural Pharmacology. 16: S21-S22. DOI: 10.1097/00008877-200509001-00068 |
0.53 |
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| 2005 |
Charney DS, Berrettini W, Biederman J, Innis RB, Nestler EJ, Rush AJ. Maintaining a Steady Course Biological Psychiatry. 58: 433-434. DOI: 10.1016/J.Biopsych.2005.09.001 |
0.394 |
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| 2004 |
McClung CA, Ulery PG, Perrotti LI, Zachariou V, Berton O, Nestler EJ. DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Research. Molecular Brain Research. 132: 146-54. PMID 15582154 DOI: 10.1016/J.Molbrainres.2004.05.014 |
0.822 |
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| 2004 |
Perrotti LI, Hadeishi Y, Ulery PG, Barrot M, Monteggia L, Duman RS, Nestler EJ. Induction of deltaFosB in reward-related brain structures after chronic stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10594-602. PMID 15564575 DOI: 10.1523/Jneurosci.2542-04.2004 |
0.817 |
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| 2004 |
Monteggia LM, Barrot M, Powell CM, Berton O, Galanis V, Gemelli T, Meuth S, Nagy A, Greene RW, Nestler EJ. Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 101: 10827-32. PMID 15249684 DOI: 10.1073/Pnas.0402141101 |
0.797 |
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| 2004 |
Tsankova NM, Kumar A, Nestler EJ. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5603-10. PMID 15201333 DOI: 10.1523/Jneurosci.0589-04.2004 |
0.481 |
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| 2004 |
Powell CM, Schoch S, Monteggia L, Barrot M, Matos MF, Feldmann N, Südhof TC, Nestler EJ. The presynaptic active zone protein RIM1alpha is critical for normal learning and memory. Neuron. 42: 143-53. PMID 15066271 DOI: 10.1016/S0896-6273(04)00146-1 |
0.725 |
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| 2004 |
Nestler EJ. Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction. Trends in Pharmacological Sciences. 25: 210-8. PMID 15063085 DOI: 10.1016/j.tips.2004.02.005 |
0.413 |
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| 2004 |
Potenza MN, Brodkin ES, Joe B, Luo X, Remmers EF, Wilder RL, Nestler EJ, Gelernter J. Genomic regions controlling corticosterone levels in rats. Biological Psychiatry. 55: 634-41. PMID 15013833 DOI: 10.1016/J.Biopsych.2003.11.005 |
0.306 |
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| 2004 |
Bolaños CA, Nestler EJ. Neurotrophic mechanisms in drug addiction. Neuromolecular Medicine. 5: 69-83. PMID 15001814 DOI: 10.1385/NMM:5:1:069 |
0.375 |
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| 2004 |
Nestler EJ, Malenka RC. The addicted brain. Scientific American. 290: 78-85. PMID 14981881 DOI: 10.1038/Scientificamerican0304-78 |
0.421 |
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| 2004 |
Chao J, Nestler EJ. Molecular neurobiology of drug addiction. Annual Review of Medicine. 55: 113-32. PMID 14746512 DOI: 10.1146/Annurev.Med.55.091902.103730 |
0.697 |
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| 2004 |
Chen J, Newton SS, Zeng L, Adams DH, Dow AL, Madsen TM, Nestler EJ, Duman RS. Downregulation of the CCAAT-enhancer binding protein beta in deltaFosB transgenic mice and by electroconvulsive seizures. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 23-31. PMID 14532910 DOI: 10.1038/sj.npp.1300289 |
0.805 |
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| 2004 |
Monteggia L, Barrot M, Powell C, Berton O, Galanis V, Meuth S, Nagy A, Greene R, Nestler E. S.19.03 An inducible gene knockout system targeted to BDNF in the brain European Neuropsychopharmacology. 14: S148. DOI: 10.1016/S0924-977X(04)80059-2 |
0.745 |
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| 2003 |
Bolaños CA, Barrot M, Berton O, Wallace-Black D, Nestler EJ. Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood. Biological Psychiatry. 54: 1317-29. PMID 14675795 DOI: 10.1016/S0006-3223(03)00570-5 |
0.702 |
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| 2003 |
Eisch AJ, Bolaños CA, de Wit J, Simonak RD, Pudiak CM, Barrot M, Verhaagen J, Nestler EJ. Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biological Psychiatry. 54: 994-1005. PMID 14625141 DOI: 10.1016/j.biopsych.2003.08.003 |
0.64 |
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| 2003 |
Zachariou V, Georgescu D, Sanchez N, Rahman Z, DiLeone R, Berton O, Neve RL, Sim-Selley LJ, Selley DE, Gold SJ, Nestler EJ. Essential role for RGS9 in opiate action. Proceedings of the National Academy of Sciences of the United States of America. 100: 13656-61. PMID 14595021 DOI: 10.1073/Pnas.2232594100 |
0.809 |
|
| 2003 |
McClung CA, Nestler EJ. Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nature Neuroscience. 6: 1208-15. PMID 14566342 DOI: 10.1038/Nn1143 |
0.7 |
|
| 2003 |
Bolaños CA, Perrotti LI, Edwards S, Eisch AJ, Barrot M, Olson VG, Russell DS, Neve RL, Nestler EJ. Phospholipase Cgamma in distinct regions of the ventral tegmental area differentially modulates mood-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7569-76. PMID 12930795 |
0.827 |
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| 2003 |
Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, ... ... Nestler EJ, et al. RGS9 modulates dopamine signaling in the basal ganglia. Neuron. 38: 941-52. PMID 12818179 DOI: 10.1016/S0896-6273(03)00321-0 |
0.823 |
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| 2003 |
DiLeone RJ, Georgescu D, Nestler EJ. Lateral hypothalamic neuropeptides in reward and drug addiction. Life Sciences. 73: 759-68. PMID 12801597 DOI: 10.1016/S0024-3205(03)00408-9 |
0.751 |
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| 2003 |
Haberstock-Debic H, Wein M, Barrot M, Colago EE, Rahman Z, Neve RL, Pickel VM, Nestler EJ, von Zastrow M, Svingos AL. Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4324-32. PMID 12764121 DOI: 10.1523/Jneurosci.23-10-04324.2003 |
0.542 |
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| 2003 |
Georgescu D, Zachariou V, Barrot M, Mieda M, Willie JT, Eisch AJ, Yanagisawa M, Nestler EJ, DiLeone RJ. Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3106-11. PMID 12716916 DOI: 10.1523/Jneurosci.23-08-03106.2003 |
0.81 |
|
| 2003 |
Peakman MC, Colby C, Perrotti LI, Tekumalla P, Carle T, Ulery P, Chao J, Duman C, Steffen C, Monteggia L, Allen MR, Stock JL, Duman RS, McNeish JD, Barrot M, ... ... Nestler EJ, et al. Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain Research. 970: 73-86. PMID 12706249 DOI: 10.1016/S0006-8993(03)02230-3 |
0.843 |
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| 2003 |
Colby CR, Whisler K, Steffen C, Nestler EJ, Self DW. Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2488-93. PMID 12657709 |
0.657 |
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| 2003 |
Gold SJ, Han MH, Herman AE, Ni YG, Pudiak CM, Aghajanian GK, Liu RJ, Potts BW, Mumby SM, Nestler EJ. Regulation of RGS proteins by chronic morphine in rat locus coeruleus. The European Journal of Neuroscience. 17: 971-80. PMID 12653973 DOI: 10.1046/J.1460-9568.2003.02529.X |
0.766 |
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| 2003 |
Shaw-Lutchman TZ, Impey S, Storm D, Nestler EJ. Regulation of CRE-mediated transcription in mouse brain by amphetamine. Synapse (New York, N.Y.). 48: 10-7. PMID 12557267 DOI: 10.1002/Syn.10172 |
0.418 |
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| 2003 |
Norrholm SD, Bibb JA, Nestler EJ, Ouimet CC, Taylor JR, Greengard P. Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5. Neuroscience. 116: 19-22. PMID 12535933 DOI: 10.1016/S0306-4522(02)00560-2 |
0.809 |
|
| 2003 |
Bolaños CA, Perrotti LI, Edwards S, Eisch AJ, Barrot M, Olson VG, Russell DS, Neve RL, Nestler EJ. Phospholipase Cγ in Distinct Regions of the Ventral Tegmental Area Differentially Modulates Mood-Related Behaviors The Journal of Neuroscience. 23: 7569-7576. DOI: 10.1523/Jneurosci.23-20-07569.2003 |
0.827 |
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| 2003 |
Colby CR, Whisler K, Steffen C, Nestler EJ, Self DW. Striatal Cell Type-Specific Overexpression of ΔFosB Enhances Incentive for Cocaine The Journal of Neuroscience. 23: 2488-2493. DOI: 10.1523/Jneurosci.23-06-02488.2003 |
0.688 |
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| 2003 |
Norrholm S, Bibb J, Nestler E, Ouimet C, Taylor J, Greengard P. Corrigendum to “cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5” Neuroscience. 119: 619. DOI: 10.1016/S0306-4522(03)00155-6 |
0.768 |
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| 2003 |
Carlezon WA, Nestler EJ. Response: What role do GluR1 subunits play in drug abuse? Trends in Neurosciences. 26: 182-183. DOI: 10.1016/S0166-2236(03)00079-1 |
0.545 |
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| 2003 |
Charney DS, Innis RB, Nestler EJ. New initiatives in Biological Psychiatry Biological Psychiatry. 53: 1-2. DOI: 10.1016/S0006-3223(02)01858-9 |
0.388 |
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| 2002 |
Nestler EJ. Common molecular and cellular substrates of addiction and memory. Neurobiology of Learning and Memory. 78: 637-47. PMID 12559841 DOI: 10.1006/Nlme.2002.4084 |
0.353 |
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| 2002 |
Brunner D, Nestler E, Leahy E. In need of high-throughput behavioral systems. Drug Discovery Today. 7: S107-12. PMID 12546875 DOI: 10.1016/S1359-6446(02)02423-6 |
0.306 |
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| 2002 |
Newton SS, Thome J, Wallace TL, Shirayama Y, Schlesinger L, Sakai N, Chen J, Neve R, Nestler EJ, Duman RS. Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10883-90. PMID 12486182 DOI: 10.1523/Jneurosci.22-24-10883.2002 |
0.696 |
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| 2002 |
Carlezon WA, Nestler EJ. Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse? Trends in Neurosciences. 25: 610-5. PMID 12446127 DOI: 10.1016/S0166-2236(02)02289-0 |
0.62 |
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| 2002 |
Chao JR, Ni YG, Bolaños CA, Rahman Z, DiLeone RJ, Nestler EJ. Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB. The European Journal of Neuroscience. 16: 1284-94. PMID 12405989 DOI: 10.1046/J.1460-9568.2002.02186.X |
0.81 |
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| 2002 |
Nestler EJ. From neurobiology to treatment: progress against addiction. Nature Neuroscience. 5: 1076-9. PMID 12403990 DOI: 10.1038/nn945 |
0.318 |
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| 2002 |
Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1 |
0.705 |
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| 2002 |
Gold SJ, Heifets BD, Pudiak CM, Potts BW, Nestler EJ. Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures. Journal of Neurochemistry. 82: 828-38. PMID 12358788 DOI: 10.1046/J.1471-4159.2002.01002.X |
0.787 |
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| 2002 |
Werme M, Messer C, Olson L, Gilden L, Thorén P, Nestler EJ, Brené S. Delta FosB regulates wheel running. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8133-8. PMID 12223567 |
0.752 |
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| 2002 |
Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, Impey S, Storm DR, Neve RL, Yin JC, Zachariou V, Nestler EJ. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proceedings of the National Academy of Sciences of the United States of America. 99: 11435-40. PMID 12165570 DOI: 10.1073/Pnas.172091899 |
0.832 |
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| 2002 |
Jentsch JD, Olausson P, Nestler EJ, Taylor JR. Stimulation of protein kinase a activity in the rat amygdala enhances reward-related learning. Biological Psychiatry. 52: 111-8. PMID 12114002 DOI: 10.1016/S0006-3223(02)01358-6 |
0.371 |
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| 2002 |
Sakai N, Thome J, Newton SS, Chen J, Kelz MB, Steffen C, Nestler EJ, Duman RS. Inducible and brain region-specific CREB transgenic mice. Molecular Pharmacology. 61: 1453-64. PMID 12021407 DOI: 10.1124/Mol.61.6.1453 |
0.699 |
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| 2002 |
Akbarian S, Rios M, Liu RJ, Gold SJ, Fong HF, Zeiler S, Coppola V, Tessarollo L, Jones KR, Nestler EJ, Aghajanian GK, Jaenisch R. Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4153-62. PMID 12019333 DOI: 10.1523/Jneurosci.22-10-04153.2002 |
0.757 |
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| 2002 |
Nakagawa S, Kim JE, Lee R, Malberg JE, Chen J, Steffen C, Zhang YJ, Nestler EJ, Duman RS. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3673-82. PMID 11978843 DOI: 10.1523/Jneurosci.22-09-03673.2002 |
0.631 |
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| 2002 |
Shaw-Lutchman TZ, Barrot M, Wallace T, Gilden L, Zachariou V, Impey S, Duman RS, Storm D, Nestler EJ. Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3663-72. PMID 11978842 DOI: 10.1523/Jneurosci.22-09-03663.2002 |
0.764 |
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| 2002 |
Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. Neurobiology of depression. Neuron. 34: 13-25. PMID 11931738 DOI: 10.1016/S0896-6273(02)00653-0 |
0.802 |
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| 2002 |
Mower AF, Liao DS, Nestler EJ, Neve RL, Ramoa AS. cAMP/Ca2+ response element-binding protein function is essential for ocular dominance plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2237-45. PMID 11896163 DOI: 10.1523/Jneurosci.22-06-02237.2002 |
0.305 |
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| 2002 |
Werme M, Messer C, Olson L, Gilden L, Thorén P, Nestler EJ, Brené S. ΔFosBRegulates Wheel Running The Journal of Neuroscience. 22: 8133-8138. DOI: 10.1523/JNEUROSCI.22-18-08133.2002 |
0.767 |
|
| 2002 |
Eisch AJ, Nestler EJ. To be or not to be: Adult neurogenesis and psychiatry Clinical Neuroscience Research. 2: 93-108. DOI: 10.1016/S1566-2772(02)00011-7 |
0.59 |
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| 2002 |
Nestler EJ. Dopamine and Gene Expression Handbook of Experimental Pharmacology. 154: 321-337. DOI: 10.1007/978-3-642-56051-4_12 |
0.33 |
|
| 2001 |
Brãuer AU, Savaskan NE, Kole MH, Plaschke M, Monteggia LM, Nestler EJ, Simburger E, Deisz RA, Ninnemann O, Nitsch R. Molecular and functional analysis of hyperpolarization-activated pacemaker channels in the hippocampus after entorhinal cortex lesion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2689-701. PMID 11726545 DOI: 10.1096/Fj.01-0235Com |
0.569 |
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