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Craig Cameron Mello, Ph.D. - Publications

Affiliations: 
Molecular Medicine University of Massachusetts Medical School, Worcester, MA, United States 
Area:
Regulation of gene expression
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/2006/mello-bio.html
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104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sun B, Kim H, Mello CC, Priess JR. The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods. Plos Genetics. 19: e1010804. PMID 37384599 DOI: 10.1371/journal.pgen.1010804  0.783
2023 Ding YH, Ochoa HJ, Ishidate T, Shirayama M, Mello CC. The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing. Cell Reports. 42: 112408. PMID 37083324 DOI: 10.1016/j.celrep.2023.112408  0.735
2022 Dai S, Tang X, Li L, Ishidate T, Ozturk AR, Chen H, Dude AL, Yan YH, Dong MQ, Shen EZ, Mello CC. A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing. Cell Reports. 40: 111265. PMID 36070689 DOI: 10.1016/j.celrep.2022.111265  0.825
2021 Ghanta KS, Chen Z, Mir A, Dokshin GA, Krishnamurthy PM, Yoon Y, Gallant J, Xu P, Zhang XO, Ozturk AR, Shin M, Idrizi F, Liu P, Gneid H, Edraki A, ... ... Mello CC, et al. 5' modifications improve potency and efficacy of DNA donors for precision genome editing. Elife. 10. PMID 34665130 DOI: 10.7554/eLife.72216  0.775
2021 Makeyeva YV, Shirayama M, Mello CC. Cues from mRNA splicing prevent default Argonaute silencing in C. elegans. Developmental Cell. PMID 34547227 DOI: 10.1016/j.devcel.2021.08.022  0.387
2021 Kim H, Ding YH, Lu S, Zuo MQ, Tan W, Conte D, Dong MQ, Mello CC. PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in . Elife. 10. PMID 34003111 DOI: 10.7554/eLife.63300  0.743
2021 Kim H, Ding YH, Zhang G, Yan YH, Conte D, Dong MQ, Mello CC. HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in . Elife. 10. PMID 34003109 DOI: 10.7554/eLife.63299  0.746
2021 Spichal M, Heestand B, Billmyre KK, Frenk S, Mello CC, Ahmed S. Germ granule dysfunction is a hallmark and mirror of Piwi mutant sterility. Nature Communications. 12: 1420. PMID 33658512 DOI: 10.1038/s41467-021-21635-0  0.391
2020 Chaves DA, Dai H, Li L, Moresco JJ, Oh ME, Conte D, Yates JR, Mello CC, Gu W. The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans. Molecular Cell. PMID 33378643 DOI: 10.1016/j.molcel.2020.12.004  0.335
2020 Ghanta KS, Mello CC. Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in . Genetics. PMID 32963112 DOI: 10.1534/genetics.120.303564  0.331
2019 Dokshin GA, Davis GM, Sawle AD, Eldridge MD, Nicholls PK, Gourley TE, Romer KA, Molesworth LW, Tatnell HR, Ozturk AR, de Rooij DG, Hannon GJ, Page DC, Mello CC, Carmell MA. GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability. Developmental Cell. PMID 31839538 DOI: 10.1016/J.Devcel.2019.11.006  0.795
2018 Dokshin GA, Ghanta KS, Piscopo KM, Mello CC. Robust Genome Editing With Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in . Genetics. PMID 30213854 DOI: 10.1534/Genetics.118.301532  0.781
2018 Ishidate T, Ozturk AR, Durning DJ, Sharma R, Shen EZ, Chen H, Seth M, Shirayama M, Mello CC. ZNFX-1 Functions within Perinuclear Nuage to Balance Epigenetic Signals. Molecular Cell. 70: 639-649.e6. PMID 29775580 DOI: 10.1016/J.Molcel.2018.04.009  0.804
2018 Tang W, Seth M, Tu S, Shen EZ, Li Q, Shirayama M, Weng Z, Mello CC. A Sex Chromosome piRNA Promotes Robust Dosage Compensation and Sex Determination in C. elegans. Developmental Cell. PMID 29456136 DOI: 10.1016/J.Devcel.2018.01.025  0.816
2018 Seth M, Shirayama M, Tang W, Shen EZ, Tu S, Lee HC, Weng Z, Mello CC. The Coding Regions of Germline mRNAs Confer Sensitivity to Argonaute Regulation in C. elegans. Cell Reports. PMID 29456100 DOI: 10.1016/J.Celrep.2018.02.009  0.804
2018 Shen EZ, Chen H, Ozturk AR, Tu S, Shirayama M, Tang W, Ding YH, Dai SY, Weng Z, Mello CC. Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline. Cell. PMID 29456082 DOI: 10.1016/J.Cell.2018.02.002  0.803
2017 Gammon DB, Ishidate T, Li L, Gu W, Silverman N, Mello CC. The Antiviral RNA Interference Response Provides Resistance to Lethal Arbovirus Infection and Vertical Transmission in Caenorhabditis elegans. Current Biology : Cb. PMID 28262484 DOI: 10.1016/J.Cub.2017.02.004  0.348
2016 Carmell MA, Dokshin GA, Skaletsky H, Hu YC, von Wolfswinkel JC, Igarashi KJ, Bellott DW, Nefedov M, Reddien PW, Enders GC, Uversky VN, Mello CC, Page DC. A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes. Elife. 5. PMID 27718356 DOI: 10.7554/Elife.19993  0.804
2016 Tang W, Tu S, Lee HC, Weng Z, Mello CC. The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans. Cell. 164: 974-984. PMID 26919432 DOI: 10.1016/J.Cell.2016.02.008  0.461
2016 Sharma U, Conine CC, Shea JM, Boskovic A, Derr AG, Bing XY, Belleannee C, Kucukural A, Serra RW, Sun F, Song L, Carone BR, Ricci EP, Li XZ, Fauquier L, ... ... Mello CC, et al. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science (New York, N.Y.). 351: 391-6. PMID 26721685 DOI: 10.1126/Science.Aad6780  0.461
2016 Carmell MA, Dokshin GA, Skaletsky H, Hu Y, Wolfswinkel JCv, Igarashi KJ, Bellott DW, Nefedov M, Reddien PW, Enders GC, Uversky VN, Mello CC, Page DC. Author response: A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes Elife. DOI: 10.7554/Elife.19993.029  0.773
2015 Gu W, Gallagher GR, Dai W, Liu P, Li R, Trombly MI, Gammon DB, Mello CC, Wang JP, Finberg RW. Influenza A virus preferentially snatches noncoding RNA caps. Rna (New York, N.Y.). PMID 26428694 DOI: 10.1261/Rna.054221.115  0.422
2015 Elewa A, Shirayama M, Kaymak E, Harrison PF, Powell DR, Du Z, Chute CD, Woolf H, Yi D, Ishidate T, Srinivasan J, Bao Z, Beilharz TH, Ryder SP, Mello CC. POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA. Developmental Cell. 34: 108-18. PMID 26096734 DOI: 10.1016/J.Devcel.2015.05.024  0.487
2015 Gammon DB, Mello CC. RNA interference-mediated antiviral defense in insects. Current Opinion in Insect Science. 8: 111-120. PMID 26034705 DOI: 10.1016/J.Cois.2015.01.006  0.411
2015 Hainer SJ, Gu W, Carone BR, Landry BD, Rando OJ, Mello CC, Fazzio TG. Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF. Genes & Development. 29: 362-78. PMID 25691467 DOI: 10.1101/Gad.253534.114  0.405
2015 Tsai HY, Chen CC, Conte D, Moresco JJ, Chaves DA, Mitani S, Yates JR, Tsai MD, Mello CC. A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi. Cell. 160: 407-19. PMID 25635455 DOI: 10.1016/J.Cell.2015.01.010  0.451
2015 Conte D, MacNeil LT, Walhout AJ, Mello CC. RNA Interference in Caenorhabditis elegans. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 109: 26.3.1-26.3.30. PMID 25559107 DOI: 10.1002/0471142727.Mb2603S109  0.399
2014 Gammon DB, Duraffour S, Rozelle DK, Hehnly H, Sharma R, Sparks ME, West CC, Chen Y, Moresco JJ, Andrei G, Connor JH, Conte D, Gundersen-Rindal DE, Marshall WL, Yates JR, ... ... Mello CC, et al. A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection. Elife. 3. PMID 24966209 DOI: 10.7554/Elife.02910  0.336
2014 Kim H, Ishidate T, Ghanta KS, Seth M, Conte D, Shirayama M, Mello CC. A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans. Genetics. 197: 1069-80. PMID 24879462 DOI: 10.1534/Genetics.114.166389  0.339
2014 Shirayama M, Stanney W, Gu W, Seth M, Mello CC. The Vasa Homolog RDE-12 engages target mRNA and multiple argonaute proteins to promote RNAi in C. elegans. Current Biology : Cb. 24: 845-51. PMID 24684931 DOI: 10.1016/J.Cub.2014.03.008  0.491
2014 Ishidate T, Elewa A, Kim S, Mello CC, Shirayama M. Divide and differentiate: CDK/Cyclins and the art of development. Cell Cycle (Georgetown, Tex.). 13: 1384-91. PMID 24675894 DOI: 10.4161/Cc.28656  0.352
2014 Gammon DB, Duraffour S, Rozelle DK, Hehnly H, Sharma R, Sparks ME, West CC, Chen Y, Moresco JJ, Andrei G, Connor JH, Conte D, Gundersen-Rindal DE, Marshall WL, Yates JR, ... ... Mello CC, et al. Author response: A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection Elife. DOI: 10.7554/Elife.02910.028  0.325
2014 Gammon DB, Duraffour S, Rozelle DK, Hehnly H, Sharma R, Sparks ME, West CC, Chen Y, Moresco JJ, Andrei G, Connor JH, Conte D, Gundersen-Rindal DE, Marshall WL, Yates JR, ... ... Mello CC, et al. A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection Elife. 2014. DOI: 10.7554/eLife.02910.001  0.332
2013 Seth M, Shirayama M, Gu W, Ishidate T, Conte D, Mello CC. The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression. Developmental Cell. 27: 656-63. PMID 24360782 DOI: 10.1016/J.Devcel.2013.11.014  0.477
2013 Conine CC, Moresco JJ, Gu W, Shirayama M, Conte D, Yates JR, Mello CC. Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans. Cell. 155: 1532-44. PMID 24360276 DOI: 10.1016/J.Cell.2013.11.032  0.474
2013 Kim S, Ishidate T, Sharma R, Soto MC, Conte D, Mello CC, Shirayama M. Wnt and CDK-1 regulate cortical release of WRM-1/β-catenin to control cell division orientation in early Caenorhabditis elegans embryos. Proceedings of the National Academy of Sciences of the United States of America. 110: E918-27. PMID 23431196 DOI: 10.1073/Pnas.1300769110  0.357
2013 Thivierge C, Makil N, Flamand M, Vasale JJ, Mello CC, Wohlschlegel J, Conte D, Duchaine TF. Erratum: Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi Nature Structural & Molecular Biology. 20: 244-244. DOI: 10.1038/nsmb0213-244d  0.399
2012 Gu W, Lee HC, Chaves D, Youngman EM, Pazour GJ, Conte D, Mello CC. CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors. Cell. 151: 1488-500. PMID 23260138 DOI: 10.1016/J.Cell.2012.11.023  0.482
2012 D'Ambrogio A, Gu W, Udagawa T, Mello CC, Richter JD. Specific miRNA stabilization by Gld2-catalyzed monoadenylation. Cell Reports. 2: 1537-45. PMID 23200856 DOI: 10.1016/J.Celrep.2012.10.023  0.356
2012 Pak J, Maniar JM, Mello CC, Fire A. Protection from feed-forward amplification in an amplified RNAi mechanism. Cell. 151: 885-99. PMID 23141544 DOI: 10.1016/J.Cell.2012.10.022  0.328
2012 Li L, Gu W, Liang C, Liu Q, Mello CC, Liu Y. The translin-TRAX complex (C3PO) is a ribonuclease in tRNA processing. Nature Structural & Molecular Biology. 19: 824-30. PMID 22773104 DOI: 10.1038/Nsmb.2337  0.439
2012 Shirayama M, Seth M, Lee HC, Gu W, Ishidate T, Conte D, Mello CC. piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline. Cell. 150: 65-77. PMID 22738726 DOI: 10.1016/J.Cell.2012.06.015  0.434
2012 Lee HC, Gu W, Shirayama M, Youngman E, Conte D, Mello CC. C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts. Cell. 150: 78-87. PMID 22738724 DOI: 10.1016/J.Cell.2012.06.016  0.48
2012 Thivierge C, Makil N, Flamand M, Vasale JJ, Mello CC, Wohlschlegel J, Conte D, Duchaine TF. Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi. Nature Structural & Molecular Biology. 19: 90-7. PMID 22179787 DOI: 10.1038/Nsmb.2186  0.473
2011 Gu W, Claycomb JM, Batista PJ, Mello CC, Conte D. Cloning Argonaute-associated small RNAs from Caenorhabditis elegans. Methods in Molecular Biology (Clifton, N.J.). 725: 251-80. PMID 21528459 DOI: 10.1007/978-1-61779-046-1_17  0.82
2011 Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, et al. MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 526-35. PMID 21179009 DOI: 10.1038/Mt.2010.279  0.397
2010 Lee HC, Li L, Gu W, Xue Z, Crosthwaite SK, Pertsemlidis A, Lewis ZA, Freitag M, Selker EU, Mello CC, Liu Y. Diverse pathways generate microRNA-like RNAs and Dicer-independent small interfering RNAs in fungi. Molecular Cell. 38: 803-14. PMID 20417140 DOI: 10.1016/J.Molcel.2010.04.005  0.462
2010 Conte D, Mello CC. Primal RNAs: The end of the beginning? Cell. 140: 452-4. PMID 20178736 DOI: 10.1016/J.Cell.2010.02.005  0.42
2010 Conine CC, Batista PJ, Gu W, Claycomb JM, Chaves DA, Shirayama M, Mello CC. Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 107: 3588-93. PMID 20133686 DOI: 10.1073/Pnas.0911685107  0.829
2010 Vasale JJ, Gu W, Thivierge C, Batista PJ, Claycomb JM, Youngman EM, Duchaine TF, Mello CC, Conte D. Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3582-7. PMID 20133583 DOI: 10.1073/Pnas.0911908107  0.818
2010 Liu J, Maduzia LL, Shirayama M, Mello CC. NMY-2 maintains cellular asymmetry and cell boundaries, and promotes a SRC-dependent asymmetric cell division. Developmental Biology. 339: 366-73. PMID 20059995 DOI: 10.1016/J.Ydbio.2009.12.041  0.379
2009 van Wolfswinkel JC, Claycomb JM, Batista PJ, Mello CC, Berezikov E, Ketting RF. CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs. Cell. 139: 135-48. PMID 19804759 DOI: 10.1016/J.Cell.2009.09.012  0.805
2009 Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, van Wolfswinkel JC, Chaves DA, Shirayama M, Mitani S, Ketting RF, Conte D, Mello CC. The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell. 139: 123-34. PMID 19804758 DOI: 10.1016/J.Cell.2009.09.014  0.826
2009 Gu W, Shirayama M, Conte D, Vasale J, Batista PJ, Claycomb JM, Moresco JJ, Youngman EM, Keys J, Stoltz MJ, Chen CC, Chaves DA, Duan S, Kasschau KD, Fahlgren N, ... ... Mello CC, et al. Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline. Molecular Cell. 36: 231-44. PMID 19800275 DOI: 10.1016/J.Molcel.2009.09.020  0.82
2008 Batista PJ, Ruby JG, Claycomb JM, Chiang R, Fahlgren N, Kasschau KD, Chaves DA, Gu W, Vasale JJ, Duan S, Conte D, Luo S, Schroth GP, Carrington JC, Bartel DP, ... Mello CC, et al. PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Molecular Cell. 31: 67-78. PMID 18571452 DOI: 10.1016/J.Molcel.2008.06.002  0.822
2007 Mello CC. Return to the RNAi world: rethinking gene expression and evolution. Cell Death and Differentiation. 14: 2013-20. PMID 18007672 DOI: 10.1038/Sj.Cdd.4402252  0.378
2007 Mello CC. Return to the RNAi world: rethinking gene expression and evolution (Nobel Lecture). Angewandte Chemie (International Ed. in English). 46: 6985-94. PMID 17712806 DOI: 10.1002/Anie.200701713  0.368
2007 Mello C. Zurück zur RNAi-Welt: Gedanken zur Genexpression und Evolution (Nobel-Vortrag) Angewandte Chemie. 119: 7114-7124. DOI: 10.1002/Ange.200701713  0.393
2006 Yigit E, Batista PJ, Bei Y, Pang KM, Chen CC, Tolia NH, Joshua-Tor L, Mitani S, Simard MJ, Mello CC. Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell. 127: 747-57. PMID 17110334 DOI: 10.1016/J.Cell.2006.09.033  0.771
2006 Hayakawa A, Leonard D, Murphy S, Hayes S, Soto M, Fogarty K, Standley C, Bellve K, Lambright D, Mello C, Corvera S. The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 11928-33. PMID 16873553 DOI: 10.1073/Pnas.0508832103  0.426
2006 Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR, Mello CC. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell. 124: 343-54. PMID 16439208 DOI: 10.1016/J.Cell.2005.11.036  0.488
2006 Shirayama M, Soto MC, Ishidate T, Kim S, Nakamura K, Bei Y, van den Heuvel S, Mello CC. The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans. Current Biology : Cb. 16: 47-55. PMID 16343905 DOI: 10.1016/J.Cub.2005.11.070  0.463
2005 Nakamura K, Kim S, Ishidate T, Bei Y, Pang K, Shirayama M, Trzepacz C, Brownell DR, Mello CC. Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos. Genes & Development. 19: 1749-54. PMID 16077004 DOI: 10.1101/Gad.1323705  0.31
2005 Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G. Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature. 436: 593-7. PMID 16049496 DOI: 10.1038/Nature04010  0.466
2005 Chen CC, Simard MJ, Tabara H, Brownell DR, McCollough JA, Mello CC. A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans. Current Biology : Cb. 15: 378-83. PMID 15723801 DOI: 10.1016/J.Cub.2005.01.009  0.525
2005 Tops BB, Tabara H, Sijen T, Simmer F, Mello CC, Plasterk RH, Ketting RF. RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans. Nucleic Acids Research. 33: 347-55. PMID 15653635 DOI: 10.1093/Nar/Gki183  0.521
2004 Mello CC, Czech MP. Micromanaging insulin secretion. Nature Medicine. 10: 1297-8. PMID 15580250 DOI: 10.1038/Nm1204-1297  0.369
2004 Grigorenko AP, Moliaka YK, Soto MC, Mello CC, Rogaev EI. The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins. Proceedings of the National Academy of Sciences of the United States of America. 101: 14955-60. PMID 15469912 DOI: 10.1073/Pnas.0406462101  0.391
2004 Mello CC, Conte D. Revealing the world of RNA interference. Nature. 431: 338-42. PMID 15372040 DOI: 10.1038/Nature02872  0.448
2004 Hutvágner G, Simard MJ, Mello CC, Zamore PD. Sequence-specific inhibition of small RNA function. Plos Biology. 2: E98. PMID 15024405 DOI: 10.1371/journal.pbio.0020098  0.335
2004 Pang KM, Ishidate T, Nakamura K, Shirayama M, Trzepacz C, Schubert CM, Priess JR, Mello CC. The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos. Developmental Biology. 265: 127-39. PMID 14697358 DOI: 10.1016/J.Ydbio.2003.09.024  0.8
2003 Shin TH, Mello CC. Chromatin regulation during C. elegans germline development. Current Opinion in Genetics & Development. 13: 455-62. PMID 14550409 DOI: 10.1016/S0959-437X(03)00109-6  0.356
2003 Venkatesan K, McManus HR, Mello CC, Smith TF, Hansen U. Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead. Nucleic Acids Research. 31: 4304-16. PMID 12888489 DOI: 10.1093/Nar/Gkg644  0.424
2003 Timmons L, Tabara H, Mello CC, Fire AZ. Inducible systemic RNA silencing in Caenorhabditis elegans. Molecular Biology of the Cell. 14: 2972-83. PMID 12857879 DOI: 10.1091/Mbc.E03-01-0858  0.468
2002 Unhavaithaya Y, Shin TH, Miliaras N, Lee J, Oyama T, Mello CC. MEP-1 and a homolog of the NURD complex component Mi-2 act together to maintain germline-soma distinctions in C. elegans. Cell. 111: 991-1002. PMID 12507426 DOI: 10.1016/S0092-8674(02)01202-3  0.47
2002 Tabara H, Yigit E, Siomi H, Mello CC. The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell. 109: 861-71. PMID 12110183 DOI: 10.1016/S0092-8674(02)00793-6  0.502
2002 Bei Y, Hogan J, Berkowitz LA, Soto M, Rocheleau CE, Pang KM, Collins J, Mello CC. SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos. Developmental Cell. 3: 113-25. PMID 12110172 DOI: 10.1016/S1534-5807(02)00185-5  0.385
2002 Grishok A, Mello CC. RNAi (Nematodes: Caenorhabditis elegans). Advances in Genetics. 46: 339-60. PMID 11931230 DOI: 10.1016/S0065-2660(02)46012-9  0.481
2002 Soto MC, Qadota H, Kasuya K, Inoue M, Tsuboi D, Mello CC, Kaibuchi K. The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans. Genes & Development. 16: 620-32. PMID 11877381 DOI: 10.1101/Gad.955702  0.412
2002 Victor M, Bei Y, Gay F, Calvo D, Mello C, Shi Y. HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans. Embo Reports. 3: 50-5. PMID 11751575 DOI: 10.1093/Embo-Reports/Kvf006  0.384
2001 Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell. 106: 23-34. PMID 11461699 DOI: 10.1016/S0092-8674(01)00431-7  0.507
2000 Parrish S, Fleenor J, Xu S, Mello C, Fire A. Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference Molecular Cell. 6: 1077-1087. PMID 11106747 DOI: 10.1016/S1097-2765(00)00106-4  0.44
2000 Grishok A, Tabara H, Mello CC. Genetic requirements for inheritance of RNAi in C. elegans. Science (New York, N.Y.). 287: 2494-7. PMID 10741970 DOI: 10.1126/Science.287.5462.2494  0.436
1999 Tabara H, Sarkissian M, Kelly WG, Fleenor J, Grishok A, Timmons L, Fire A, Mello CC. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell. 99: 123-32. PMID 10535731 DOI: 10.1016/S0092-8674(00)81644-X  0.473
1999 Shin TH, Yasuda J, Rocheleau CE, Lin R, Soto M, Bei Y, Davis RJ, Mello CC. MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans. Molecular Cell. 4: 275-80. PMID 10488343 DOI: 10.1016/S1097-2765(00)80375-5  0.395
1999 Rocheleau CE, Yasuda J, Shin TH, Lin R, Sawa H, Okano H, Priess JR, Davis RJ, Mello CC. WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. Cell. 97: 717-26. PMID 10380924 DOI: 10.1016/S0092-8674(00)80784-9  0.757
1999 Batchelder C, Dunn MA, Choy B, Suh Y, Cassie C, Shim EY, Shin TH, Mello C, Seydoux G, Blackwell TK. Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. Genes & Development. 13: 202-12. PMID 9925644 DOI: 10.1101/Gad.13.2.202  0.435
1999 Tabara H, Hill RJ, Mello CC, Priess JR, Kohara Y. pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans. Development (Cambridge, England). 126: 1-11. PMID 9834181  0.764
1998 Tabara H, Grishok A, Mello CC. RNAi in C. elegans: soaking in the genome sequence. Science (New York, N.Y.). 282: 430-1. PMID 9841401 DOI: 10.1126/Science.282.5388.430  0.4
1998 Shi Y, Mello C. A CBP/p300 homolog specifies multiple differentiation pathways in Caenorhabditis elegans Genes and Development. 12: 943-955. PMID 9531533 DOI: 10.1101/Gad.12.7.943  0.429
1998 Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391: 806-11. PMID 9486653 DOI: 10.1038/35888  0.458
1997 Rocheleau CE, Downs WD, Lin R, Wittmann C, Bei Y, Cha YH, Ali M, Priess JR, Mello CC. Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos. Cell. 90: 707-16. PMID 9288750 DOI: 10.1016/S0092-8674(00)80531-0  0.757
1996 Watts JL, Etemad-Moghadam B, Guo S, Boyd L, Draper BW, Mello CC, Priess JR, Kemphues KJ. par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3. Development (Cambridge, England). 122: 3133-40. PMID 8898226  0.751
1996 Draper BW, Mello CC, Bowerman B, Hardin J, Priess JR. MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos. Cell. 87: 205-16. PMID 8861905 DOI: 10.1016/S0092-8674(00)81339-2  0.777
1996 Seydoux G, Mello CC, Pettitt J, Wood WB, Priess JR, Fire A. Repression of gene expression in the embryonic germ lineage of C. elegans. Nature. 382: 713-6. PMID 8751441 DOI: 10.1038/382713A0  0.79
1996 Mello CC, Schubert C, Draper B, Zhang W, Lobel R, Priess JR. The PIE-1 protein and germline specification in C. elegans embryos. Nature. 382: 710-2. PMID 8751440 DOI: 10.1038/382710A0  0.809
1996 Mickey KM, Mello CC, Montgomery MK, Fire A, Priess JR. An inductive interaction in 4-cell stage C. elegans embryos involves APX-1 expression in the signalling cell. Development (Cambridge, England). 122: 1791-8. PMID 8674418  0.769
1995 Mello C, Fire A. Chapter 19 DNA Transformation Methods in Cell Biology. 48: 451-482. DOI: 10.1016/S0091-679X(08)61399-0  0.306
1994 Mello CC, Draper BW, Priess JR. The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo. Cell. 77: 95-106. PMID 8156602  0.764
1994 Levitan DJ, Boyd L, Mello CC, Kemphues KJ, Stinchcomb DT. par-2, a gene required for blastomere asymmetry in Caenorhabditis elegans, encodes zinc-finger and ATP-binding motifs. Proceedings of the National Academy of Sciences of the United States of America. 91: 6108-12. PMID 8016123 DOI: 10.1073/Pnas.91.13.6108  0.792
1993 Bowerman B, Draper BW, Mello CC, Priess JR. The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos. Cell. 74: 443-52. PMID 8348611 DOI: 10.1016/0092-8674(93)80046-H  0.772
1993 Sibley MH, Johnson JJ, Mello CC, Kramer JM. Genetic identification, sequence, and alternative splicing of the Caenorhabditis elegans alpha 2(IV) collagen gene. The Journal of Cell Biology. 123: 255-64. PMID 7691828 DOI: 10.1083/Jcb.123.1.255  0.346
1992 Mello CC, Draper BW, Krause M, Weintraub H, Priess JR. The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos. Cell. 70: 163-76. PMID 1623520 DOI: 10.1016/0092-8674(92)90542-K  0.739
1991 Mello CC, Kramer JM, Stinchcomb D, Ambros V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. The Embo Journal. 10: 3959-70. PMID 1935914 DOI: 10.1002/J.1460-2075.1991.Tb04966.X  0.768
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