Olaf S. Andersen, M.D. - Publications

Affiliations: 
Physiology Cornell Medical College 
Area:
Membrane biophysics, ion channels

218 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ashrafuzzaman M, Koeppe RE, Andersen OS. Intrinsic Lipid Curvature and Bilayer Elasticity as Regulators of Channel Function: A Comparative Single-Molecule Study. International Journal of Molecular Sciences. 25. PMID 38474005 DOI: 10.3390/ijms25052758  0.459
2022 Maer AM, Rusinova R, Providence LL, Ingólfsson HI, Collingwood SA, Lundbæk JA, Andersen OS. Regulation of Gramicidin Channel Function Solely by Changes in Lipid Intrinsic Curvature. Frontiers in Physiology. 13: 836789. PMID 35350699 DOI: 10.3389/fphys.2022.836789  0.378
2021 Rusinova R, He C, Andersen OS. Mechanisms underlying drug-mediated regulation of membrane protein function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34753824 DOI: 10.1073/pnas.2113229118  0.362
2021 Ghovanloo MR, Choudhury K, Bandaru TS, Fouda MA, Rayani K, Rusinova R, Phaterpekar T, Nelkenbrecher K, Watkins AR, Poburko D, Thewalt J, Andersen OS, Delemotte L, Goodchild SJ, Ruben PC. Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity. The Journal of General Physiology. 153. PMID 33836525 DOI: 10.1085/jgp.202012701  0.742
2020 Sun D, Peyear TA, Bennett WFD, Holcomb M, He S, Zhu F, Lightstone FC, Andersen OS, Ingólfsson HI. Assessing the Perturbing Effects of Drugs on Lipid Bilayers using Gramicidin Channel-Based and Assays. Journal of Medicinal Chemistry. PMID 32945672 DOI: 10.1021/Acs.Jmedchem.0C00958  0.439
2020 Rusinova R, Zhang K, Andersen OS. Beta-Blockers Alter Lipid Bilayer Properties Biophysical Journal. 118: 381a. DOI: 10.1016/J.Bpj.2019.11.2175  0.317
2020 Sanford RL, Andersen OS. Antipsychotics Alter Lipid Bilayer Properties Biophysical Journal. 118: 229a. DOI: 10.1016/J.Bpj.2019.11.1356  0.37
2019 Sun D, Peyear TA, Bennett WFD, Andersen OS, Lightstone FC, Ingólfsson HI. Molecular Mechanism for Gramicidin Dimerization and Dissociation in Bilayers of Different Thickness. Biophysical Journal. PMID 31676135 DOI: 10.1016/J.Bpj.2019.09.044  0.54
2019 Park S, Yeom MS, Andersen OS, Pastor RW, Im W. Quantitative Characterization of Protein-Lipid Interactions by Free Energy Simulation Between Binary Bilayers. Journal of Chemical Theory and Computation. PMID 31560853 DOI: 10.1021/Acs.Jctc.9B00815  0.491
2019 Kapoor R, Peyear TA, Koeppe RE, Andersen OS. Antidepressants are modifiers of lipid bilayer properties. The Journal of General Physiology. 151: 342-356. PMID 30796095 DOI: 10.1085/Jgp.201812263  0.52
2019 Doktorova M, Heberle FA, Marquardt D, Rusinova R, Sanford RL, Peyear TA, Katsaras J, Feigenson GW, Weinstein H, Andersen OS. Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles. Biophysical Journal. PMID 30755300 DOI: 10.1016/J.Bpj.2019.01.016  0.497
2019 Falzone ME, Rheinberger J, Lee BC, Peyear T, Sasset L, Raczkowski AM, Eng ET, Di Lorenzo A, Andersen OS, Nimigean CM, Accardi A. Structural basis of Ca-dependent activation and lipid transport by a TMEM16 scramblase. Elife. 8. PMID 30648972 DOI: 10.7554/Elife.43229  0.388
2019 Brownd M, McKay MJ, Greathouse DV, Andersen OS, Koeppe RE. Novel F13,F15 Gramicidin Subunits Predicted to Cross Bilayer Membranes and form Ion Channels Biophysical Journal. 116: 512a. DOI: 10.1016/J.Bpj.2018.11.2762  0.41
2019 Rusinova R, Andersen O. Drug Regulation of Ion Channel Function Involves Both Direct and Bilayer-Mediated Mechanisms Biophysical Journal. 116: 220a. DOI: 10.1016/J.Bpj.2018.11.1211  0.446
2018 Zhang M, Peyear T, Patmanidis I, Greathouse DV, Marrink SJ, Andersen OS, Ingólfsson HI. Fluorinated Alcohols' Effects on Lipid Bilayer Properties. Biophysical Journal. PMID 30077334 DOI: 10.1016/J.Bpj.2018.07.010  0.404
2018 Dockendorff C, Gandhi DM, Kimball IH, Eum KS, Rusinova R, Ingólfsson HI, Kapoor R, Peyear T, Dodge MW, Martin SF, Aldrich R, Andersen OS, Sack JT. Synthetic analogs of the snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT) reveal that lipid bilayer perturbation does not underlie its modulation of voltage-gated potassium channels. Biochemistry. PMID 29616558 DOI: 10.1021/Acs.Biochem.8B00292  0.554
2018 Posson DJ, Rusinova R, Andersen OS, Nimigean CM. Stopped-Flow Fluorometric Ion Flux Assay for Ligand-Gated Ion Channel Studies. Methods in Molecular Biology (Clifton, N.J.). 1684: 223-235. PMID 29058195 DOI: 10.1007/978-1-4939-7362-0_17  0.502
2018 Brownd M, McKay MJ, Greathouse DV, Andersen OS, Koeppe RE. Gramicidin Subunits that Cross Membranes and form Ion Channels Biophysical Journal. 114: 454a. DOI: 10.1016/J.Bpj.2017.11.2509  0.489
2018 Baker HA, Peyear T, Andersen OS. Cyclosporine a Demonstrates Bilayer Modification with Slow Kinetics Biophysical Journal. 114: 259a. DOI: 10.1016/J.Bpj.2017.11.1506  0.342
2017 Lum K, Ingólfsson HI, Koeppe RE, Andersen OS. Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation. Biophysical Journal. 113: 1757-1767. PMID 29045870 DOI: 10.1016/J.Bpj.2017.08.049  0.477
2017 Beaven AH, Sodt AJ, Pastor RW, Koeppe RE, Andersen OS, Im W. Characterizing Residue-Bilayer Interactions Using Gramicidin A as a Scaffold and Tryptophan Substitutions as Probes. Journal of Chemical Theory and Computation. PMID 28870079 DOI: 10.1021/Acs.Jctc.7B00400  0.457
2017 Herold KF, Andersen OS, Hemmings HC. Divergent effects of anesthetics on lipid bilayer properties and sodium channel function. European Biophysics Journal : Ebj. PMID 28695248 DOI: 10.1007/S00249-017-1239-1  0.551
2017 O'Donnell JP, Cooley RB, Kelly CM, Miller K, Andersen OS, Rusinova R, Sondermann H. Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin. Structure (London, England : 1993). PMID 28602821 DOI: 10.1016/J.Str.2017.05.007  0.359
2017 Sodt AJ, Beaven AH, Andersen OS, Im W, Pastor RW. Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model. Biophysical Journal. 112: 1198-1213. PMID 28355547 DOI: 10.1016/J.Bpj.2017.01.035  0.447
2017 Beaven AH, Maer AM, Sodt AJ, Rui H, Pastor RW, Andersen OS, Im W. Gramicidin A Channel Formation Induces Local Lipid Redistribution I: Experiment and Simulation. Biophysical Journal. 112: 1185-1197. PMID 28355546 DOI: 10.1016/J.Bpj.2017.01.028  0.417
2017 Herold KF, Sanford RL, Lee W, Andersen OS, Hemmings HC. Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265069 DOI: 10.1073/Pnas.1611717114  0.521
2017 Shore DM, Iaea DB, Rusinova R, Khelashvili G, Cuendet MA, Andersen OS, Maxfield FR, Weinstein H. Vectorial Cholesterol Transport by STARD4 is Mediated by Specific PIP 2 Membrane Composition Biophysical Journal. 112: 87a. DOI: 10.1016/J.Bpj.2016.11.511  0.382
2017 Peyear T, Rusinova R, Andersen OS. Examining the Translocation of Amphiphiles across Lipid Bilayers using a Gramicidin Channel-Based Fluorescent Assay Biophysical Journal. 112: 521a. DOI: 10.1016/J.Bpj.2016.11.2815  0.482
2017 Lea Sanford R, Chao W, Chiaravalli-Giganti J, Luz A, Glickman JF, Andersen OS. Membranes Matter: Predicting Drug Toxicity Biophysical Journal. 112: 519a. DOI: 10.1016/J.Bpj.2016.11.2804  0.379
2017 Dockendorff C, Gandhi D, Kimball I, Eum KS, Rusinova R, Ingólfsson H, Kapoor R, Peyear T, Martin SF, Aldrich RW, Andersen OS, Sack J. Lipid Bilayer Perturbation by the Snail Toxin 6-Bromo-2-Mercaptotryptamine Dimer does not Account for its Modulation of Voltage-Gated Potassium Channels Biophysical Journal. 112: 246a-247a. DOI: 10.1016/J.Bpj.2016.11.1348  0.53
2017 Herold K, Lee W, Sanford R, Andersen OS, Hemmings HC. General Anesthetics Minimally affect Lipid Bilayer Properties at Clinical Concentrations Biophysical Journal. 112: 227a. DOI: 10.1016/J.Bpj.2016.11.1249  0.471
2017 Rusinova R, Andersen OS. Regulation of KcsA by Bilayer-Modifying Molecules Biophysical Journal. 112: 225a-226a. DOI: 10.1016/J.Bpj.2016.11.1243  0.535
2016 Redondo-Morata L, Lea Sanford R, Andersen OS, Scheuring S. Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers. Biophysical Journal. 111: 363-72. PMID 27463138 DOI: 10.1016/J.Bpj.2016.06.016  0.438
2016 Sanford RL, Andersen OS. Bilayer Modifying Effects of Antipsychotics of Different Generations Biophysical Journal. 110: 245a. DOI: 10.1016/J.Bpj.2015.11.1350  0.464
2015 Rusinova R, Koeppe RE, Andersen OS. A general mechanism for drug promiscuity: Studies with amiodarone and other antiarrhythmics. The Journal of General Physiology. PMID 26573624 DOI: 10.1016/J.Bpj.2015.11.492  0.483
2015 Ramsey NB, Andersen OS. Bilayer Effects of Antimalarial Compounds. Plos One. 10: e0142401. PMID 26551613 DOI: 10.1371/Journal.Pone.0142401  0.322
2015 Posson DJ, Rusinova R, Andersen OS, Nimigean CM. Calcium ions open a selectivity filter gate during activation of the MthK potassium channel. Nature Communications. 6: 8342. PMID 26395539 DOI: 10.1038/Ncomms9342  0.468
2015 Sanford RL, Chao W, Chiaravalli-Giganti J, Luz A, Glickman JF, Andersen OS. Predicting Drug Toxicity: Early Detection of Likely Failures in Drug Development Biophysical Journal. 108: 84a. DOI: 10.1016/J.Bpj.2014.11.489  0.373
2015 Ramsey N, Andersen O. Bilayer Perturbation is a Predictive Parameter for Antimalarial Development Biophysical Journal. 108: 83a-84a. DOI: 10.1016/J.Bpj.2014.11.488  0.381
2015 Rusinova R, Koeppe RE, Andersen OS. A General Mechanism for Off-Target Effects: Studies with Amiodarone and other Antiarrhythmics Biophysical Journal. 108: 498a. DOI: 10.1016/J.Bpj.2014.11.2724  0.491
2015 Beaven AH, Sodt AJ, Andersen OS, Pastor RW, Im W. Ion Channel Regulation by Lipid Bilayers: Theory & Simulation of Deformed Membranes around Gramicidin A Biophysical Journal. 108: 209a. DOI: 10.1016/J.Bpj.2014.11.1155  0.517
2014 Herold KF, Sanford RL, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC. Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties. The Journal of General Physiology. 144: 545-60. PMID 25385786 DOI: 10.1085/Jgp.201411172  0.524
2014 Ingólfsson HI, Thakur P, Herold KF, Hobart EA, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K, Maretzky T, Hemmings HC, Blobel C, Marrink SJ, Koçer A, ... ... Andersen OS, et al. Phytochemicals perturb membranes and promiscuously alter protein function. Acs Chemical Biology. 9: 1788-98. PMID 24901212 DOI: 10.1021/Cb500086E  0.499
2014 Rusinova R, Kim DM, Nimigean CM, Andersen OS. Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay. Biophysical Journal. 106: 1070-8. PMID 24606931 DOI: 10.1016/J.Bpj.2014.01.027  0.538
2014 McCoy JG, Rusinova R, Kim DM, Kowal J, Banerjee S, Jaramillo Cartagena A, Thompson AN, Kolmakova-Partensky L, Stahlberg H, Andersen OS, Nimigean CM. A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics. The Journal of Biological Chemistry. 289: 9535-46. PMID 24515111 DOI: 10.1074/Jbc.M113.543389  0.505
2014 Vorobyov I, Olson TE, Kim JH, Koeppe RE, Andersen OS, Allen TW. Ion-induced defect permeation of lipid membranes. Biophysical Journal. 106: 586-97. PMID 24507599 DOI: 10.1016/J.Bpj.2013.12.027  0.423
2014 Beaven AH, Sodt AJ, Greathouse DV, Koeppe RE, Pastor RW, Andersen OS, Im W. All-Atom Simulation and Continuum Elastic Theory of Gramicidin a in Binary Component Lipid Bilayers Biophysical Journal. 106: 801a. DOI: 10.1016/J.Bpj.2013.11.4389  0.419
2014 Posson DJ, Rusinova R, Andersen OS, Nimigean CM. Calcium-Dependent Gating in MthK K+ Channels Occurs at the Selectivity Filter Biophysical Journal. 106: 642a. DOI: 10.1016/J.Bpj.2013.11.3553  0.454
2014 Herold KF, Lee W, Sanford RL, Andersen OS, Hemmings HC. General Anesthetics do not Alter Lipid Bilayer Properties at Clinically Relevant Concentrations Biophysical Journal. 106: 515a. DOI: 10.1016/J.Bpj.2013.11.2877  0.504
2013 Andersen OS. Membrane proteins: Through thick and thin. Nature Chemical Biology. 9: 667-8. PMID 24141219 DOI: 10.1038/Nchembio.1368  0.412
2013 Bruno MJ, Rusinova R, Gleason NJ, Koeppe RE, Andersen OS. Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation. Faraday Discussions. 161: 461-80; discussion 5. PMID 23805753 DOI: 10.1039/C2Fd20092A  0.485
2013 Alejo JL, Blanchard SC, Andersen OS. Small-molecule photostabilizing agents are modifiers of lipid bilayer properties. Biophysical Journal. 104: 2410-8. PMID 23746513 DOI: 10.1016/J.Bpj.2013.04.039  0.467
2013 Rusinova R, Hobart EA, Koeppe RE, Andersen OS. Phosphoinositides alter lipid bilayer properties. The Journal of General Physiology. 141: 673-90. PMID 23712549 DOI: 10.1085/Jgp.201310960  0.538
2013 Tibbs GR, Rowley TJ, Sanford RL, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD. HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 345: 363-73. PMID 23549867 DOI: 10.1124/Jpet.113.203620  0.418
2013 Lee KI, Pastor RW, Andersen OS, Im W. Assessing smectic liquid-crystal continuum models for elastic bilayer deformations. Chemistry and Physics of Lipids. 169: 19-26. PMID 23348553 DOI: 10.1016/J.Chemphyslip.2013.01.005  0.459
2013 Ingólfsson HI, Thakur P, Herold KF, Maretzky T, Hall K, Zwama M, Yilmaz D, Hemmings HC, Blobel C, Koçer A, Sack J, Andersen OS. Phytochemicals Promiscuously Alter Membrane Protein Function and Bilayer Properties Biophysical Journal. 104: 93a. DOI: 10.1016/J.Bpj.2012.11.557  0.517
2013 Sanford RL, Al'Aref SJ, Koeppe RE, Andersen OS. Statins Alter Lipid Bilayer Properties Biophysical Journal. 104: 86a. DOI: 10.1016/J.Bpj.2012.11.515  0.554
2013 Ramsey N, Andersen O. Camp Pathway Modifiers Alter Lipid Bilayer Properties Biophysical Journal. 104: 85a. DOI: 10.1016/J.Bpj.2012.11.514  0.343
2013 Andersen OS. Interactions of Drugs and Other Amphiphiles with Membranes: Implications for Membrane Protein Function Biophysical Journal. 104: 543a. DOI: 10.1016/J.Bpj.2012.11.3010  0.538
2013 Beaven AH, Pastor RW, Andersen OS, Im W. Exploring Protein-Lipid Interactions using Gramicidin a as a Model System Biophysical Journal. 104: 432a-433a. DOI: 10.1016/J.Bpj.2012.11.2406  0.464
2013 Herold KF, Lee W, Sanford RL, Eger EI, Andersen OS, Hemmings HC. Combined Stopped-Flow and Electrophysiological Experiments Suggest Direct Sodium Channel Inhibition by Model Fluorobenzene Anesthetics Biophysical Journal. 104: 427a-428a. DOI: 10.1016/J.Bpj.2012.11.2379  0.556
2013 Rusinova R, Kim D, Nimigean C, Andersen OS. A New Assay for Ion Channel Function using Stopped Flow Spectrofluorometry Biophysical Journal. 104: 373a. DOI: 10.1016/J.Bpj.2012.11.2074  0.498
2013 Ramirez DA, Andersen OS, Leidy C. Modulation of Elastic Properties through Unsaturated Lipid Content as a Mechanism for Inducing Resistance to Amphiphilic Antimicrobial Peptides Biophysical Journal. 104: 237a. DOI: 10.1016/J.Bpj.2012.11.1338  0.409
2012 Andersen OS. Perspectives on: conformational coupling in ion channels. The Journal of General Physiology. 140: 595-7. PMID 23183695 DOI: 10.1085/Jgp.201210926  0.412
2012 Howery AE, Elvington S, Abraham SJ, Choi KH, Dworschak-Simpson S, Phillips S, Ryan CM, Sanford RL, Almqvist J, Tran K, Chew TA, Zachariae U, Andersen OS, Whitelegge J, Matulef K, et al. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chemistry & Biology. 19: 1460-70. PMID 23177200 DOI: 10.1016/J.Chembiol.2012.09.017  0.476
2012 Kim T, Lee KI, Morris P, Pastor RW, Andersen OS, Im W. Influence of hydrophobic mismatch on structures and dynamics of gramicidin a and lipid bilayers. Biophysical Journal. 102: 1551-60. PMID 22500755 DOI: 10.1016/J.Bpj.2012.03.014  0.506
2012 Sanford RL, Al'Aref SJ, Koeppe RE, Andersen OS. Statins Modify Lipid Bilayer Properties Biophysical Journal. 102: 84a. DOI: 10.1016/J.Bpj.2011.11.484  0.555
2012 Matulef KI, Howery A, Sanford RL, Phillips S, Simpson S, Abraham S, Whitelegge J, Du Bois J, Andersen OS, Maduke M. Characterization of a Novel CLC-ec1 Inhibitor Biophysical Journal. 102: 520a. DOI: 10.1016/J.Bpj.2011.11.2845  0.353
2012 Mondal S, Khelashvili G, Khangulova (Johnston) J, Wang H, Provasi D, Andersen OS, Filizola M, Weinstein H. Interaction with the Membrane Uncovers Essential Differences Between Highly Homologous GPCRs Biophysical Journal. 102: 514a. DOI: 10.1016/J.Bpj.2011.11.2814  0.394
2012 Vorobyov I, Koeppe R, Andersen OS, Allen TW. Origins of Non-Selective Ion Transport across Lipid Bilayers Biophysical Journal. 102: 335a. DOI: 10.1016/J.Bpj.2011.11.1834  0.397
2012 Il Lee K, Kim T, Pastor RW, Andersen OS, Im W. Assessment of Membrane Deformation Continuum Elastic Models Based on Molecular Simulations of Gramicidin A Biophysical Journal. 102: 296a. DOI: 10.1016/J.Bpj.2011.11.1637  0.426
2012 Gardner D, Andersen OS, Levin LR. Membranes, Ions, and Signals: An Integrated, Multimedia, Biophysics Module for First-Year Medical Students Biophysical Journal. 102: 210a. DOI: 10.1016/J.Bpj.2011.11.1148  0.356
2011 Mondal S, Khelashvili G, Shan J, Andersen OS, Weinstein H. Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors. Biophysical Journal. 101: 2092-101. PMID 22067146 DOI: 10.1016/J.Bpj.2011.09.037  0.406
2011 Ingólfsson HI, Koeppe RE, Andersen OS. Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. Febs Letters. 585: 3101-5. PMID 21896274 DOI: 10.1016/J.Febslet.2011.08.040  0.518
2011 Rusinova R, Herold KF, Sanford RL, Greathouse DV, Hemmings HC, Andersen OS. Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery. The Journal of General Physiology. 138: 249-70. PMID 21788612 DOI: 10.1085/Jgp.201010529  0.552
2011 Greisen P, Lum K, Ashrafuzzaman M, Greathouse DV, Andersen OS, Lundbæk JA. Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling. Proceedings of the National Academy of Sciences of the United States of America. 108: 12717-22. PMID 21768343 DOI: 10.1073/Pnas.1103192108  0.445
2011 Ingólfsson HI, Li Y, Vostrikov VV, Gu H, Hinton JF, Koeppe RE, Roux B, Andersen OS. Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. I: molecular dynamics simulations. The Journal of Physical Chemistry. B. 115: 7417-26. PMID 21574563 DOI: 10.1021/Jp200904D  0.413
2011 Vostrikov VV, Gu H, Ingólfsson HI, Hinton JF, Andersen OS, Roux B, Koeppe RE. Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. II: nuclear magnetic resonance experiments. The Journal of Physical Chemistry. B. 115: 7427-32. PMID 21574558 DOI: 10.1021/Jp200906Y  0.336
2011 Gu H, Lum K, Kim JH, Greathouse DV, Andersen OS, Koeppe RE. The membrane interface dictates different anchor roles for "inner pair" and "outer pair" tryptophan indole rings in gramicidin A channels. Biochemistry. 50: 4855-66. PMID 21539360 DOI: 10.1021/Bi200136E  0.478
2011 Stember JN, Andersen O. A one-dimensional continuum elastic model for membrane-embedded gramicidin dimer dissociation. Plos One. 6: e15563. PMID 21326605 DOI: 10.1371/Journal.Pone.0015563  0.562
2011 Ingólfsson HI, Andersen OS. Alcohol Effects on Lipid Bilayer Properties as Measured using a Gramicidin-Based Fluorescence Assay Biophysical Journal. 100: 35a. DOI: 10.1016/J.Bpj.2010.12.394  0.32
2011 Morris PM, Andersen OS, Im W. Exploring Hydrophobic Mismatch using Molecular Dynamics Simulations of Gramicidin A in Lipid Bilayers Biophysical Journal. 100: 501a. DOI: 10.1016/J.Bpj.2010.12.2933  0.551
2011 Lum K, Ingólfsson HI, Koeppe RE, Andersen OS. Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation and Gating Biophysical Journal. 100: 501a. DOI: 10.1016/J.Bpj.2010.12.2932  0.454
2011 Fletcher WR, Sanford RL, Kapoor R, Andersen OS. Bilayer-Modifying Potential of Limonene and its Metabolites Biophysical Journal. 100: 500a. DOI: 10.1016/J.Bpj.2010.12.2930  0.512
2011 Zhang M, Ingólfsson HI, Andersen OS. Effects of Fluorinated Alcohols on Lipid Bilayers Properties Biophysical Journal. 100: 500a. DOI: 10.1016/J.Bpj.2010.12.2929  0.32
2011 Al'Aref SJ, Sanford RL, Koeppe RE, Andersen OS. Statins Modify Bilayer Mechanical Properties Biophysical Journal. 100: 500a. DOI: 10.1016/J.Bpj.2010.12.2928  0.564
2011 Sanford RL, Al'Aref SJ, Koeppe RE, Andersen OS. Fenamates Alter Bilayer Properties Biophysical Journal. 100: 500a. DOI: 10.1016/J.Bpj.2010.12.2927  0.484
2011 Mondal S, Khelashvili G, Shan J, Shi L, Andersen O, Weinstein H. Quantitative Analysis of Membrane Deformation by Multi-Helical Transmembrane Proteins Biophysical Journal. 100: 492a. DOI: 10.1016/J.Bpj.2010.12.2883  0.443
2010 Ingólfsson HI, Sanford RL, Kapoor R, Andersen OS. Gramicidin-based fluorescence assay; for determining small molecules potential for modifying lipid bilayer properties. Journal of Visualized Experiments : Jove. PMID 20972414 DOI: 10.3791/2131  0.514
2010 Li Y, Andersen OS, Roux B. Energetics of double-ion occupancy in the gramicidin A channel. The Journal of Physical Chemistry. B. 114: 13881-8. PMID 20939567 DOI: 10.1021/Jp105820U  0.422
2010 Khelashvili G, Mondal S, Andersen OS, Weinstein H. Cholesterol modulates the membrane effects and spatial organization of membrane-penetrating ligands for G-protein coupled receptors. The Journal of Physical Chemistry. B. 114: 12046-57. PMID 20804205 DOI: 10.1021/Jp106373R  0.415
2010 Lundbaek JA, Koeppe RE, Andersen OS. Amphiphile regulation of ion channel function by changes in the bilayer spring constant. Proceedings of the National Academy of Sciences of the United States of America. 107: 15427-30. PMID 20713738 DOI: 10.1073/Pnas.1007455107  0.456
2010 Daily AE, Kim JH, Greathouse DV, Andersen OS, Koeppe RE. Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels. Biochemistry. 49: 6856-65. PMID 20695525 DOI: 10.1021/Bi100857G  0.542
2010 Yu H, Mazzanti CL, Whitfield TW, Koeppe RE, Andersen OS, Roux B. A combined experimental and theoretical study of ion solvation in liquid N-methylacetamide. Journal of the American Chemical Society. 132: 10847-56. PMID 20681718 DOI: 10.1021/Ja103270W  0.394
2010 Ingólfsson HI, Andersen OS. Screening for small molecules' bilayer-modifying potential using a gramicidin-based fluorescence assay. Assay and Drug Development Technologies. 8: 427-36. PMID 20233091 DOI: 10.1089/Adt.2009.0250  0.484
2010 Lundbaek JA, Collingwood SA, Ingólfsson HI, Kapoor R, Andersen OS. Lipid bilayer regulation of membrane protein function: gramicidin channels as molecular force probes. Journal of the Royal Society, Interface / the Royal Society. 7: 373-95. PMID 19940001 DOI: 10.1098/Rsif.2009.0443  0.467
2010 Lundbaek JA, Andersen OS. Amphiphile-Regulation of Ion Channel Function by Changes in a Transferable Lipid Bilayer Spring Constant Biophysical Journal. 98: 482a. DOI: 10.1016/J.Bpj.2009.12.2624  0.537
2010 Al'Aref SJ, Koeppe RE, Andersen OS. NSAIDs Alter Bilayer Properties by a Common Mechanism Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2613  0.567
2010 Rusinova R, Herold KF, Koeppe RE, Hemmings H, Andersen OS. Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2612  0.572
2010 Kapoor R, Ingolfsson HI, Koeppe RE, Andersen O. Antidepressants Modify Lipid Bilayer Properties Biophysical Journal. 98: 479a-480a. DOI: 10.1016/J.Bpj.2009.12.2611  0.498
2010 Ingolfsson HI, Andersen OS. High Throughput Gramicidin-Based Fluorescence Assay to Screen for Small Molecules' Bilayer-Perturbing Potential Biophysical Journal. 98: 479a. DOI: 10.1016/J.Bpj.2009.12.2610  0.496
2010 Li Y, Andersen OS, Roux B. Mechanisms of Ion Permeation through Gramicidin a Channels Biophysical Journal. 98: 330a. DOI: 10.1016/J.Bpj.2009.12.1791  0.475
2009 Rusinova R, Koeppe RE, Andersen OS. The Insulin-sensitizers Troglitazone And Rosiglitazone Alter Lipid Bilayer Properties Biophysical Journal. 96: 158a. DOI: 10.1016/J.Bpj.2008.12.720  0.548
2009 Ingolfsson HI, Vostrikov VV, Gu H, Koeppe RE, Hinton JF, Roux B, Allen TW, Andersen OS. Evaluating Gramicidin A Channel Backbone Dynamics by Molecular Dynamics and Nuclear Magnetic Resonance Biophysical Journal. 96: 152a-153a. DOI: 10.1016/J.Bpj.2008.12.688  0.437
2009 Al'Aref SJ, Andersen OS, Koeppe RE. NSAIDs Alter Lipid Bilayer Mechanical Properties Biophysical Journal. 96: 150a. DOI: 10.1016/J.Bpj.2008.12.676  0.501
2009 Yu H, Whitfield TW, Noskov SY, Mazzanti CL, Koeppe RE, Andersen OS, Roux B. Development of a Drude Polarizable Force Field for Ion-water and Ion-NMA Interactions and Application to Selectivity in Ion Channels Biophysical Journal. 96: 660a. DOI: 10.1016/J.Bpj.2008.12.3488  0.338
2009 Collingwood SA, Andersen OS, Hurd F, Greathouse DV. Investigating the Effects of Acylated Lactoferricin Peptides on the Properties of Lipid Bilayers Using Gramicidin A Channels as Probes Biophysical Journal. 96: 457a. DOI: 10.1016/J.Bpj.2008.12.2348  0.469
2009 Li Y, Allen TW, Andersen OS, Roux B. Potential of Mean Force Calculations of Ion Permeation in Gramicidin A Channel Biophysical Journal. 96: 365a. DOI: 10.1016/J.Bpj.2008.12.1966  0.441
2008 Kapoor R, Kim JH, Ingolfson H, Andersen OS. Preparation of artificial bilayers for electrophysiology experiments. Journal of Visualized Experiments : Jove. PMID 19078935 DOI: 10.3791/1033  0.555
2008 Ingolfson H, Kapoor R, Collingwood SA, Andersen OS. Single molecule methods for monitoring changes in bilayer elastic properties. Journal of Visualized Experiments : Jove. PMID 19066527 DOI: 10.3791/1032  0.513
2008 Ashrafuzzaman M, Andersen OS, McElhaney RN. The antimicrobial peptide gramicidin S permeabilizes phospholipid bilayer membranes without forming discrete ion channels. Biochimica Et Biophysica Acta. 1778: 2814-22. PMID 18809374 DOI: 10.1016/J.Bbamem.2008.08.017  0.493
2008 Roux B, Andersen OS, Allen TW. Comment on "Free energy simulations of single and double ion occupancy in gramicidin A" [J. Chem. Phys. 126, 105103 (2007)]. The Journal of Chemical Physics. 128: 227101; author reply. PMID 18554067 DOI: 10.1063/1.2931568  0.436
2008 Sun H, Greathouse DV, Andersen OS, Koeppe RE. The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels. The Journal of Biological Chemistry. 283: 22233-43. PMID 18550546 DOI: 10.1074/Jbc.M802074200  0.515
2008 Andersen OS. Perspectives on how to drug an ion channel. The Journal of General Physiology. 131: 395-7. PMID 18411334 DOI: 10.1083/Jcb1815Oia18  0.327
2007 Andersen OS, Bruno MJ, Sun H, Koeppe RE. Single-molecule methods for monitoring changes in bilayer elastic properties. Methods in Molecular Biology (Clifton, N.J.). 400: 543-70. PMID 17951759 DOI: 10.1007/978-1-59745-519-0_37  0.499
2007 Ingolfsson HI, Koeppe RE, Andersen OS. Curcumin is a modulator of bilayer material properties. Biochemistry. 46: 10384-91. PMID 17705403 DOI: 10.1021/Bi701013N  0.531
2007 Adachi S, Nagao T, Ingolfsson HI, Maxfield FR, Andersen OS, Kopelovich L, Weinstein IB. The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells. Cancer Research. 67: 6493-501. PMID 17616711 DOI: 10.1158/0008-5472.Can-07-0411  0.382
2007 Bruno MJ, Koeppe RE, Andersen OS. Docosahexaenoic acid alters bilayer elastic properties. Proceedings of the National Academy of Sciences of the United States of America. 104: 9638-43. PMID 17535898 DOI: 10.1073/Pnas.0701015104  0.498
2007 Andersen OS, Koeppe RE. Bilayer thickness and membrane protein function: an energetic perspective. Annual Review of Biophysics and Biomolecular Structure. 36: 107-30. PMID 17263662 DOI: 10.1146/Annurev.Biophys.36.040306.132643  0.431
2007 Andersen OS. Perspectives on membrane protein insertion, protein-bilayer interactions, and amino acid side hydrophobicity Journal of General Physiology. 129: 351-352. DOI: 10.1085/Jgp.200709792  0.368
2006 Jordan JB, Shobana S, Andersen OS, Hinton JF. Effects of glycine substitutions on the structure and function of gramicidin a channels. Biochemistry. 45: 14012-20. PMID 17115696 DOI: 10.1021/bi061560z  0.44
2006 Artigas P, Al'aref SJ, Hobart EA, Díaz LF, Sakaguchi M, Straw S, Andersen OS. 2,3-butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independent mechanisms: the role of bilayer material properties. Molecular Pharmacology. 70: 2015-26. PMID 16966478 DOI: 10.1124/Mol.106.026070  0.533
2006 Allen TW, Andersen OS, Roux B. Molecular dynamics - potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channels. Biophysical Chemistry. 124: 251-67. PMID 16781050 DOI: 10.1016/J.Bpc.2006.04.015  0.474
2006 Allen TW, Andersen OS, Roux B. Ion permeation through a narrow channel: using gramicidin to ascertain all-atom molecular dynamics potential of mean force methodology and biomolecular force fields. Biophysical Journal. 90: 3447-68. PMID 16500984 DOI: 10.1529/Biophysj.105.077073  0.413
2006 Ashrafuzzaman M, Lampson MA, Greathouse DV, Koeppe RE, Andersen OS. Manipulating lipid bilayer material properties using biologically active amphipathic molecules Journal of Physics Condensed Matter. 18: S1235-S1255. DOI: 10.1088/0953-8984/18/28/S08  0.54
2005 Lundbaek JA, Birn P, Tape SE, Toombes GE, Søgaard R, Koeppe RE, Gruner SM, Hansen AJ, Andersen OS. Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity. Molecular Pharmacology. 68: 680-9. PMID 15967874 DOI: 10.1124/Mol.105.013573  0.564
2005 Andersen OS, Koeppe RE, Roux B. Gramicidin channels. Ieee Transactions On Nanobioscience. 4: 10-20. PMID 15816168 DOI: 10.1109/TNB.2004.842470  0.428
2005 Andersen OS. The 58th annual meeting and symposium of the society of general physiologists: lipid signaling in physiology. The Journal of General Physiology. 125: 103-10. PMID 15684090 DOI: 10.1085/Jgp.200509256  0.358
2004 Allen TW, Andersen OS, Roux B. On the importance of atomic fluctuations, protein flexibility, and solvent in ion permeation. The Journal of General Physiology. 124: 679-90. PMID 15572347 DOI: 10.1085/Jgp.200409111  0.425
2004 Suchyna TM, Tape SE, Koeppe RE, Andersen OS, Sachs F, Gottlieb PA. Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers. Nature. 430: 235-40. PMID 15241420 DOI: 10.1038/Nature02743  0.496
2004 Liu L, Yang T, Bruno MJ, Andersen OS, Simon SA. Voltage-gated ion channels in nociceptors: modulation by cGMP. Journal of Neurophysiology. 92: 2323-32. PMID 15175369 DOI: 10.1152/Jn.00355.2004  0.512
2004 Lundbaek JA, Birn P, Hansen AJ, Søgaard R, Nielsen C, Girshman J, Bruno MJ, Tape SE, Egebjerg J, Greathouse DV, Mattice GL, Koeppe RE, Andersen OS. Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol. The Journal of General Physiology. 123: 599-621. PMID 15111647 DOI: 10.1085/Jgp.200308996  0.562
2004 Andersen OS. The 57th Annual Meeting and Symposium of the Society of General Physiologists: the biology of chloride. The Journal of General Physiology. 123: 89-94. PMID 14744983 DOI: 10.1085/Jgp.200409018  0.365
2004 Allen TW, Andersen OS, Roux B. Energetics of ion conduction through the gramicidin channel. Proceedings of the National Academy of Sciences of the United States of America. 101: 117-22. PMID 14691245 DOI: 10.1073/Pnas.2635314100  0.413
2003 Hwang TC, Koeppe RE, Andersen OS. Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics. Biochemistry. 42: 13646-58. PMID 14622011 DOI: 10.1021/Bi034887Y  0.562
2003 Allen TW, Andersen OS, Roux B. Structure of gramicidin a in a lipid bilayer environment determined using molecular dynamics simulations and solid-state NMR data. Journal of the American Chemical Society. 125: 9868-77. PMID 12904055 DOI: 10.1021/Ja029317K  0.37
2003 Goforth RL, Chi AK, Greathouse DV, Providence LL, Koeppe RE, Andersen OS. Hydrophobic coupling of lipid bilayer energetics to channel function. The Journal of General Physiology. 121: 477-93. PMID 12719487 DOI: 10.1085/Jgp.200308797  0.557
2003 Lundbaek JA, Andersen OS, Werge T, Nielsen C. Cholesterol-induced protein sorting: an analysis of energetic feasibility. Biophysical Journal. 84: 2080-9. PMID 12609909 DOI: 10.1016/S0006-3495(03)75015-2  0.392
2003 Sham SS, Shobana S, Townsley LE, Jordan JB, Fernandez JQ, Andersen OS, Greathouse DV, Hinton JF. The structure, cation binding, transport, and conductance of Gly15-gramicidin A incorporated into SDS micelles and PC/PG vesicles. Biochemistry. 42: 1401-9. PMID 12578352 DOI: 10.1021/Bi0204286  0.461
2003 Kopito RR, Green WN, Andersen O. The 56th Annual Meeting and Symposium of the Society of General Physiologists: trafficking of transporters. The Journal of General Physiology. 121: 73-9. PMID 12566536 DOI: 10.1085/Jgp.20038806  0.556
2002 Lingappa VR, Rutkowski DT, Hegde RS, Andersen OS. Conformational control through translocational regulation: a new view of secretory and membrane protein folding. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 741-8. PMID 12210535 DOI: 10.1002/Bies.10130  0.363
2002 Andersen OS. Perspectives on the identity of the H+ channel involved in the respiratory burst Journal of General Physiology. 120: 757. DOI: 10.1085/Jgp.20028734  0.39
2001 Jude AR, Providence LL, Schmutzer SE, Shobana S, Greathouse DV, Andersen OS, Koeppe R. Peptide backbone chemistry and membrane channel function: effects of a single amide-to-ester replacement on gramicidin channel structure and function. Biochemistry. 40: 1460-72. PMID 11170474 DOI: 10.1021/Bi001562Y  0.489
2001 Kuyucak S, Andersen OS, Chung SH. Models of permeation in ion channels Reports On Progress in Physics. 64: 1427-1472. DOI: 10.1088/0034-4885/64/11/202  0.492
2000 Nielsen C, Andersen OS. Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature. Biophysical Journal. 79: 2583-604. PMID 11053132 DOI: 10.1016/S0006-3495(00)76498-8  0.352
2000 Koeppe RE, Hatchett J, Jude AR, Providence LL, Andersen OS, Greathouse DV. Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels. Biochemistry. 39: 2235-42. PMID 10694389 DOI: 10.1021/Bi9920679  0.419
1999 Andersen OS. Sequencing and the single channel. Biophysical Journal. 77: 2899-901. PMID 10585913 DOI: 10.1016/S0006-3495(99)77122-5  0.484
1999 Koeppe RE, Greathouse DV, Providence LL, Shobana S, Andersen OS. Design and characterization of gramicidin channels with side chain or backbone mutations. Novartis Foundation Symposium. 225: 44-55; discussion 55. PMID 10472047 DOI: 10.1002/9780470515716.Ch4  0.556
1999 Andersen OS, Apell HJ, Bamberg E, Busath DD, Koeppe RE, Sigworth FJ, Szabo G, Urry DW, Woolley A. Gramicidin channel controversy--the structure in a lipid environment. Nature Structural Biology. 6: 609; discussion 611-. PMID 10404209 DOI: 10.1038/10648  0.506
1999 Andersen OS. Perspectives on ion permeation The Journal of General Physiology. 113: 763-4. PMID 10352026 DOI: 10.1085/Jgp.113.6.763  0.449
1999 Lundbaek JA, Andersen OS. Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channels. Biophysical Journal. 76: 889-95. PMID 9929490 DOI: 10.1016/S0006-3495(99)77252-8  0.536
1999 Andersen OS. Perspectives on ion channel assembly The Journal of General Physiology. 113: 161. PMID 9925814 DOI: 10.1085/Jgp.113.2.161  0.422
1999 Greathouse DV, Koeppe RE, Providence LL, Shobana S, Andersen OS. Design and characterization of gramicidin channels. Methods in Enzymology. 294: 525-50. PMID 9916247 DOI: 10.1016/S0076-6879(99)94031-4  0.53
1999 Andersen OS, Nielsen C, Maer AM, Lundbaek JA, Goulian M, Koeppe RE. Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers. Methods in Enzymology. 294: 208-24. PMID 9916229 DOI: 10.1016/S0076-6879(99)94013-2  0.475
1999 Jude AR, Greathouse DV, Koeppe RE, Providence LL, Andersen OS. Modulation of gramicidin channel structure and function by the aliphatic "spacer" residues 10, 12, and 14 between the tryptophans. Biochemistry. 38: 1030-9. PMID 9893999 DOI: 10.1021/Bi982043M  0.457
1998 Andersen OS. Editorial: Perspectives in General Physiology The Journal of General Physiology. 111: 615-615. PMID 9565398 DOI: 10.1085/Jgp.111.5.615  0.387
1998 Nielsen C, Goulian M, Andersen OS. Energetics of inclusion-induced bilayer deformations. Biophysical Journal. 74: 1966-83. PMID 9545056 DOI: 10.1016/S0006-3495(98)77904-4  0.384
1998 Goulian M, Mesquita ON, Fygenson DK, Nielsen C, Andersen OS, Libchaber A. Gramicidin channel kinetics under tension. Biophysical Journal. 74: 328-37. PMID 9449333 DOI: 10.1016/S0006-3495(98)77790-2  0.478
1998 Andersen OS, Jennings ML. The 51st Annual Meeting and Symposium of the Society of General Physiologists: Mechanisms of secretion Journal of General Physiology. 111: vii-xii. DOI: 10.1085/Jgp.111.2.Vii  0.337
1998 Andersen OS, Greathouse DV, Providence LL, Becker MD, Koeppe RE. Importance of tryptophan dipoles for protein function: F-fluorination of tryptophans in gramicidin a channels Journal of the American Chemical Society. 120: 5142-5146. DOI: 10.1021/Ja980182L  0.445
1997 Girshman J, Greathouse DV, Koeppe RE, Andersen OS. Gramicidin channels in phospholipid bilayers with unsaturated acyl chains. Biophysical Journal. 73: 1310-9. PMID 9284299 DOI: 10.1016/S0006-3495(97)78164-5  0.5
1997 Mobashery N, Nielsen C, Andersen OS. The conformational preference of gramicidin channels is a function of lipid bilayer thickness. Febs Letters. 412: 15-20. PMID 9257681 DOI: 10.1016/S0014-5793(97)00709-6  0.564
1997 Lundbaek JA, Maer AM, Andersen OS. Lipid bilayer electrostatic energy, curvature stress, and assembly of gramicidin channels. Biochemistry. 36: 5695-701. PMID 9153409 DOI: 10.1021/Bi9619841  0.463
1997 Andersen OS. The 50th Annual Meeting and Symposium of the Society of General Physiologists. Cytoskeletal regulation of membrane function. The Journal of General Physiology. 109: xi-xiv. PMID 9101401 DOI: 10.1085/Jgp.109.4.Xi  0.301
1996 Andersen OS, Saberwal G, Greathouse DV, Koeppe RE. Gramicidin channels--a solvable membrane "protein" folding problem. Indian Journal of Biochemistry & Biophysics. 33: 331-42. PMID 9029812  0.459
1996 Koeppe RE, Andersen OS. Engineering the gramicidin channel Annual Review of Biophysics and Biomolecular Structure. 25: 231-258. PMID 8800470 DOI: 10.1146/Annurev.Bb.25.060196.001311  0.426
1996 Lundbaek JA, Birn P, Girshman J, Hansen AJ, Andersen OS. Membrane stiffness and channel function. Biochemistry. 35: 3825-30. PMID 8620005 DOI: 10.1021/Bi952250B  0.546
1995 Providence LL, Andersen OS, Greathouse DV, Koeppe RE, Bittman R. Gramicidin channel function does not depend on phospholipid chirality. Biochemistry. 34: 16404-11. PMID 8845367 DOI: 10.1021/Bi00050A022  0.536
1995 Mattice GL, Koeppe RE, Providence LL, Andersen OS. Stabilizing effect of D-alanine2 in gramicidin channels. Biochemistry. 34: 6827-37. PMID 7538788 DOI: 10.1021/Bi00020A029  0.46
1995 Oiki S, Koeppe RE, Andersen OS. Voltage-dependent gating of an asymmetric gramicidin channel. Proceedings of the National Academy of Sciences of the United States of America. 92: 2121-5. PMID 7534411 DOI: 10.1073/Pnas.92.6.2121  0.447
1994 Lundbaek JA, Andersen OS. Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers. The Journal of General Physiology. 104: 645-73. PMID 7530766 DOI: 10.1085/Jgp.104.4.645  0.567
1994 Oiki S, Koeppe RE, Andersen OS. Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue. Biophysical Journal. 66: 1823-32. PMID 7521224 DOI: 10.1016/S0006-3495(94)80976-2  0.488
1994 Koeppe RE, Greathouse DV, Jude A, Saberwal G, Providence LL, Andersen OS. Helix sense of gramicidin channels as a "nonlocal" function of the primary sequence. The Journal of Biological Chemistry. 269: 12567-76. PMID 7513690  0.322
1994 He K, Ludtke SJ, Wu Y, Huang HW, Andersen OS, Greathouse D, Koeppe RE. Closed state of gramicidin channel detected by X-ray in-plane scattering. Biophysical Chemistry. 49: 83-9. PMID 7510532 DOI: 10.1016/0301-4622(93)E0085-J  0.5
1993 Daumas P, Andersen OS. Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy. The Journal of General Physiology. 101: 27-43. PMID 8382258 DOI: 10.1085/Jgp.101.1.27  0.365
1993 Durkin JT, Providence LL, Koeppe RE, Andersen OS. Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel. Journal of Molecular Biology. 231: 1102-21. PMID 7685829 DOI: 10.1006/Jmbi.1993.1355  0.505
1992 Vogt TC, Killian JA, De Kruijff B, Andersen OS. Influence of acylation on the channel characteristics of gramicidin A. Biochemistry. 31: 7320-4. PMID 1380824 DOI: 10.1021/bi00147a016  0.429
1992 Williams LP, Narcessian EJ, Andersen OS, Waller GR, Taylor MJ, Lazenby JP, Hinton JF, Koeppe RE. Molecular and channel-forming characteristics of gramicidin K's: a family of naturally occurring acylated gramicidins. Biochemistry. 31: 7311-9. PMID 1380823  0.415
1992 Fonseca V, Daumas P, Ranjalahy-Rasoloarijao L, Heitz F, Lazaro R, Trudelle Y, Andersen OS. Gramicidin channels that have no tryptophan residues. Biochemistry. 31: 5340-50. PMID 1376621 DOI: 10.1021/Bi00138A014  0.548
1992 Oiki S, Koeppe RE, Andersen OS. A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels. Biophysical Journal. 62: 28-30. PMID 1376169 DOI: 10.1016/S0006-3495(92)81768-X  0.464
1992 Becker MD, Koeppe RE, Andersen OS. Amino acid substitutions and ion channel function. Model-dependent conclusions. Biophysical Journal. 62: 25-7. PMID 1376168 DOI: 10.1016/S0006-3495(92)81767-8  0.411
1992 Durkin JT, Providence LL, Koeppe RE, Andersen OS. Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues. Biophysical Journal. 62: 145-57; discussion 1. PMID 1376164 DOI: 10.1016/S0006-3495(92)81801-5  0.471
1992 Koeppe RE, Providence LL, Greathouse DV, Heitz F, Trudelle Y, Purdie N, Andersen OS. On the helix sense of gramicidin A single channels. Proteins. 12: 49-62. PMID 1372741 DOI: 10.1002/Prot.340120107  0.451
1992 Cifu AS, Koeppe RE, Andersen OS. On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer. Biophysical Journal. 61: 189-203. PMID 1371703 DOI: 10.1016/S0006-3495(92)81826-X  0.491
1992 Chabala LD, Andersen OS. Carbodiimide modification reduces the conductance and increases the tetrodotoxin sensitivity in batrachotoxin-modified sodium channels. Pflã¼Gers Archiv : European Journal of Physiology. 421: 262-9. PMID 1326748 DOI: 10.1007/Bf00374836  0.476
1992 Andersen OS, Koeppe RE. Molecular determinants of channel function. Physiological Reviews. 72: S89-158. PMID 1279736 DOI: 10.1152/Physrev.1992.72.Suppl_4.S89  0.5
1991 Becker MD, Greathouse DV, Koeppe RE, Andersen OS. Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration. Biochemistry. 30: 8830-9. PMID 1716152 DOI: 10.1021/Bi00100A015  0.49
1991 Green WN, Andersen OS. Surface charges and ion channel function. Annual Review of Physiology. 53: 341-59. PMID 1710438 DOI: 10.1146/Annurev.Ph.53.030191.002013  0.644
1991 Chabala LD, Urban BW, Weiss LB, Green WN, Andersen OS. Steady-state gating of batrachotoxin-modified sodium channels. Variability and electrolyte-dependent modulation. The Journal of General Physiology. 98: 197-224. PMID 1658190 DOI: 10.1085/Jgp.98.1.197  0.662
1990 Sawyer DB, Williams LP, Whaley WL, Koeppe RE, Andersen OS. Gramicidins A, B, and C form structurally equivalent ion channels. Biophysical Journal. 58: 1207-12. PMID 1705449 DOI: 10.1016/S0006-3495(90)82461-9  0.484
1990 O'Connell AM, Koeppe RE, Andersen OS. Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association. Science (New York, N.Y.). 250: 1256-9. PMID 1700867 DOI: 10.1126/Science.1700867  0.548
1990 Sawyer DB, Koeppe RE, Andersen OS. Gramicidin single-channel properties show no solvent-history dependence. Biophysical Journal. 57: 515-23. PMID 1689593 DOI: 10.1016/S0006-3495(90)82567-4  0.497
1990 Koeppe RE, Mazet JL, Andersen OS. Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels. Biochemistry. 29: 512-20. PMID 1689177 DOI: 10.1021/Bi00454A027  0.473
1990 Durkin JT, Koeppe RE, Andersen OS. Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence. Journal of Molecular Biology. 211: 221-34. PMID 1688951 DOI: 10.1016/0022-2836(90)90022-E  0.509
1989 Bjerrum PJ, Andersen OS, Borders CL, Wieth JO. Functional carboxyl groups in the red cell anion exchange protein. Modification with an impermeant carbodiimide. The Journal of General Physiology. 93: 813-39. PMID 2738575 DOI: 10.1085/Jgp.93.5.813  0.355
1989 Palmer LG, Andersen OS. Interactions of amiloride and small monovalent cations with the epithelial sodium channel. Inferences about the nature of the channel pore. Biophysical Journal. 55: 779-87. PMID 2541821 DOI: 10.1016/S0006-3495(89)82876-0  0.48
1989 Sawyer DB, Andersen OS. Platelet-activating factor is a general membrane perturbant. Biochimica Et Biophysica Acta. 987: 129-32. PMID 2480815 DOI: 10.1016/0005-2736(89)90464-1  0.423
1989 Andersen OS. Kinetics of ion movement mediated by carriers and channels. Methods in Enzymology. 171: 62-112. PMID 2480507 DOI: 10.1016/S0076-6879(89)71007-7  0.343
1989 Sawyer DB, Koeppe RE, Andersen OS. Induction of conductance heterogeneity in gramicidin channels. Biochemistry. 28: 6571-83. PMID 2477060 DOI: 10.1021/Bi00442A007  0.476
1987 Green WN, Weiss LB, Andersen OS. Batrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures. The Journal of General Physiology. 89: 873-903. PMID 2440978 DOI: 10.1085/Jgp.89.6.873  0.674
1987 Green WN, Weiss LB, Andersen OS. Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block. The Journal of General Physiology. 89: 841-72. PMID 2440977 DOI: 10.1085/Jgp.89.6.841  0.69
1987 Busath DD, Andersen OS, Koeppe RE. On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study. Biophysical Journal. 51: 79-88. PMID 2432954 DOI: 10.1016/S0006-3495(87)83313-1  0.487
1986 Durkin JT, Andersen OS, Blout ER, Heitz F, Koeppe RE, Trudelle Y. Structural information from functional measurements: single-channel studies on gramicidin analogues. Biophysical Journal. 49: 118-21. PMID 19431612 DOI: 10.1016/S0006-3495(86)83618-9  0.416
1986 Green WN, Andersen OS. Surface charges near the guanidinium neurotoxin binding site. Annals of the New York Academy of Sciences. 479: 306-12. PMID 3468845 DOI: 10.1111/J.1749-6632.1986.Tb15577.X  0.532
1986 Russell EW, Weiss LB, Navetta FI, Koeppe RE, Andersen OS. Single-channel studies on linear gramicidins with altered amino acid side chains. Effects of altering the polarity of the side chain at position 1 in gramicidin A. Biophysical Journal. 49: 673-86. PMID 2421794 DOI: 10.1016/S0006-3495(86)83694-3  0.457
1984 Mazet JL, Andersen OS, Koeppe RE. Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11. Biophysical Journal. 45: 263-76. PMID 6201199 DOI: 10.1016/S0006-3495(84)84153-3  0.449
1984 Andersen OS. Gramicidin channels. Annual Review of Physiology. 46: 531-48. PMID 6201133 DOI: 10.1146/annurev.ph.46.030184.002531  0.377
1984 GREEN WN, WEISS LB, ANDERSEN OS. Batrachotoxin-Modified Sodium Channels in Lipid Bilayers Annals of the New York Academy of Sciences. 435: 548-550. DOI: 10.1111/J.1749-6632.1984.TB13879.X  0.442
1984 Green WN, Weiss LB, Andersen OS. Batrachotoxin-modified sodium channels in lipid bilayers Annals of the New York Academy of Sciences. 548-550. DOI: 10.1111/J.1749-6632.1984.Tb13879.X  0.709
1983 Andersen OS. Ion movement through gramicidin A channels. Studies on the diffusion-controlled association step. Biophysical Journal. 41: 147-65. PMID 6188502 DOI: 10.1016/S0006-3495(83)84416-6  0.466
1983 Andersen OS. Ion movement through gramicidin A channels. Interfacial polarization effects on single-channel current measurements. Biophysical Journal. 41: 135-46. PMID 6188501 DOI: 10.1016/S0006-3495(83)84415-4  0.45
1983 Andersen OS. Ion movement through gramicidin A channels. Single-channel measurements at very high potentials. Biophysical Journal. 41: 119-33. PMID 6188500 DOI: 10.1016/S0006-3495(83)84414-2  0.497
1982 Muller RU, Andersen OS. Monazomycin-induced single channels. II. Origin of the voltage dependence of the macroscopic conductance. The Journal of General Physiology. 80: 427-49. PMID 6292331 DOI: 10.1085/Jgp.80.3.427  0.686
1982 Andersen OS, Muller RU. Monazomycin-induced single channels. I. Characterization of the elementary conductance events. The Journal of General Physiology. 80: 403-26. PMID 6292330 DOI: 10.1085/Jgp.80.3.403  0.692
1982 Wieth JO, Andersen OS, Brahm J, Bjerrum PJ, Borders CL. Chloride--bicarbonate exchange in red blood cells: physiology of transport and chemical modification of binding sites. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 299: 383-99. PMID 6130537 DOI: 10.1098/Rstb.1982.0139  0.332
1981 Finkelstein A, Andersen OS. The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport. The Journal of Membrane Biology. 59: 155-71. PMID 6165825 DOI: 10.1007/Bf01875422  0.485
1978 Andersen OS, Feldberg S, Nakadomari H, Levy S, McLaughlin S. Electrostatic interactions among hydrophobic ions in lipid bilayer membranes. Biophysical Journal. 21: 35-70. PMID 620077 DOI: 10.1016/S0006-3495(78)85507-6  0.423
1976 Andersen OS, Finkelstein A, Katz I, Cass A. Effect of phloretin on the permeability of thin lipid membranes. The Journal of General Physiology. 67: 749-71. PMID 946975 DOI: 10.1085/Jgp.67.6.749  0.411
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