Jack Penney - Publications

Affiliations: 
Massachusetts General Hospital, Boston, MA 
Area:
basal ganglia, Parkinson's disease, Huntington's disease

148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, et al. Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials. Jama Neurology. 1-9. PMID 26569098 DOI: 10.1001/Jamaneurol.2015.2736  0.73
2009 Brocklebank D, Gayán J, Andresen JM, Roberts SA, Young AB, Snodgrass SR, Penney JB, Ramos-Arroyo MA, Cha JJ, Rosas HD, Hersch SM, Feigin A, Cherny SS, Wexler NS, Housman DE, et al. Repeat instability in the 27-39 CAG range of the HD gene in the Venezuelan kindreds: Counseling implications. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 425-9. PMID 18712713 DOI: 10.1002/Ajmg.B.30826  0.653
2004 Deng YP, Albin RL, Penney JB, Young AB, Anderson KD, Reiner A. Differential loss of striatal projection systems in Huntington's disease: a quantitative immunohistochemical study. Journal of Chemical Neuroanatomy. 27: 143-64. PMID 15183201 DOI: 10.1016/j.jchemneu.2004.02.005  0.464
2004 Wexler NS, Lorimer J, Porter J, Gomez F, Moskowitz C, Shackell E, Marder K, Penchaszadeh G, Roberts SA, Gayán J, Brocklebank D, Cherny SS, Cardon LR, Gray J, Dlouhy SR, ... ... Penney JB, et al. Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. Proceedings of the National Academy of Sciences of the United States of America. 101: 3498-503. PMID 14993615 DOI: 10.1073/Pnas.0308679101  0.658
2002 Spektor BS, Miller DW, Hollingsworth ZR, Kaneko YA, Solano SM, Johnson JM, Penney JB, Young AB, Luthi-Carter R. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Research. Molecular Brain Research. 102: 118-28. PMID 12191502 DOI: 10.1016/S0169-328X(02)00216-4  0.508
2001 Shoulson I, Penney J, McDermott M, Schwid S, Kayson E, Chase T, Fahn S, Greenamyre JT, Lang A, Siderowf A, Pearson N, Harrison M, Rost E, Colcher A, Lloyd M, et al. A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease. Neurology. 56: 455-62. PMID 11222787  0.486
2001 Cha JH, Farrell LA, Ahmed SF, Frey A, Hsiao-Ashe KK, Young AB, Penney JB, Locascio JJ, Hyman BT, Irizarry MC. Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein. Neurobiology of Disease. 8: 90-102. PMID 11162243 DOI: 10.1006/Nbdi.2000.0330  0.533
2001 Orlando LR, Alsdorf SA, Penney JB, Young AB. The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity. Experimental Neurology. 167: 196-204. PMID 11161608 DOI: 10.1006/exnr.2000.7542  0.537
2000 Augood SJ, Hollingsworth ZR, Standaert DG, Emson PC, Penney JB. Localization of dopaminergic markers in the human subthalamic nucleus. The Journal of Comparative Neurology. 421: 247-55. PMID 10813785 DOI: 10.1002/(Sici)1096-9861(20000529)421:2<247::Aid-Cne9>3.0.Co;2-F  0.729
2000 Küppenbender KD, Standaert DG, Feuerstein TJ, Penney JB, Young AB, Landwehrmeyer GB. Expression of NMDA receptor subunit mRNAs in neurochemically identified projection and interneurons in the human striatum. The Journal of Comparative Neurology. 419: 407-21. PMID 10742712 DOI: 10.1002/(SICI)1096-9861(20000417)419:4<407::AID-CNE1>3.0.CO;2-I  0.656
2000 Solano SM, Miller DW, Augood SJ, Young AB, Penney JB. Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: genes associated with familial Parkinson's disease. Annals of Neurology. 47: 201-10. PMID 10665491 DOI: 10.1002/1531-8249(200002)47:2<201::AID-ANA10>3.0.CO;2-F  0.701
1999 Augood SJ, Martin DM, Ozelius LJ, Breakefield XO, Penney JB, Standaert DG. Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain. Annals of Neurology. 46: 761-9. PMID 10553994 DOI: 10.1002/1531-8249(199911)46:5<761::AID-ANA12>3.0.CO;2-Z  0.728
1999 Kosinski CM, Risso Bradley S, Conn PJ, Levey AI, Landwehrmeyer GB, Penney JB, Young AB, Standaert DG. Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. The Journal of Comparative Neurology. 415: 266-84. PMID 10545164 DOI: 10.1002/(SICI)1096-9861(19991213)415:2<266::AID-CNE9>3.0.CO;2-7  0.677
1999 Cha JH, Frey AS, Alsdorf SA, Kerner JA, Kosinski CM, Mangiarini L, Penney JB, Davies SW, Bates GP, Young AB. Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 981-9. PMID 10434296 DOI: 10.1098/Rstb.1999.0449  0.555
1999 Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature. 399: 263-7. PMID 10353249 DOI: 10.1038/20446  0.453
1999 Sapp E, Penney J, Young A, Aronin N, Vonsattel JP, DiFiglia M. Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease. Journal of Neuropathology and Experimental Neurology. 58: 165-73. PMID 10029099 DOI: 10.1097/00005072-199902000-00006  0.456
1999 Standaert DG, Friberg IK, Landwehrmeyer GB, Young AB, Penney JB. Expression of NMDA glutamate receptor subunit mRNAs in neurochemically identified projection and interneurons in the striatum of the rat. Brain Research. Molecular Brain Research. 64: 11-23. PMID 9889300 DOI: 10.1016/S0169-328X(98)00293-9  0.689
1998 Kerner JA, Standaert DG, Penney JB, Young AB, Landwehrmeyer GB. Simultaneous isotopic and nonisotopic in situ hybridization histochemistry with cRNA probes. Brain Research. Brain Research Protocols. 3: 22-32. PMID 9767088 DOI: 10.1016/S1385-299X(98)00017-8  0.588
1998 Kosinski CM, Standaert DG, Testa CM, Penney JB, Young AB. Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat. Neuroscience. 86: 783-98. PMID 9692717 DOI: 10.1016/S0306-4522(97)00654-4  0.784
1998 Cha JH, Kosinski CM, Kerner JA, Alsdorf SA, Mangiarini L, Davies SW, Penney JB, Bates GP, Young AB. Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene. Proceedings of the National Academy of Sciences of the United States of America. 95: 6480-5. PMID 9600992 DOI: 10.1073/pnas.95.11.6480  0.562
1998 Augood SJ, Penney JB, Friberg IK, Breakefield XO, Young AB, Ozelius LJ, Standaert DG. Expression of the early-onset torsion dystonia gene (DYT1) in human brain. Annals of Neurology. 43: 669-73. PMID 9585364 DOI: 10.1002/ana.410430518  0.761
1998 Counihan TJ, Landwehrmeyer GB, Standaert DG, Kosinski CM, Scherzer CR, Daggett LP, Veliçelebi G, Young AB, Penney JB. Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: mesencephalic dopaminergic neurons. The Journal of Comparative Neurology. 390: 91-101. PMID 9456178 DOI: 10.1002/(SICI)1096-9861(19980105)390:1<91::AID-CNE8>3.0.CO;2-L  0.684
1998 Scherzer CR, Landwehrmeyer GB, Kerner JA, Counihan TJ, Kosinski CM, Standaert DG, Daggett LP, Veliçelebi G, Penney JB, Young AB. Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex. The Journal of Comparative Neurology. 390: 75-90. PMID 9456177 DOI: 10.1002/(SICI)1096-9861(19980105)390:1<75::AID-CNE7>3.0.CO;2-N  0.652
1998 Kosinski CM, Standaert DG, Counihan TJ, Scherzer CR, Kerner JA, Daggett LP, Veliçelebi G, Penney JB, Young AB, Landwehrmeyer GB. Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus. The Journal of Comparative Neurology. 390: 63-74. PMID 9456176 DOI: 10.1002/(SICI)1096-9861(19980105)390:1<63::AID-CNE6>3.0.CO;2-O  0.657
1997 Testa CM, Hollingsworth ZR, Shinozaki H, Penney JB, Young AB. Selective metabotropic receptor agonists distinguish non-ionotropic glutamate binding sites. Brain Research. 773: 15-27. PMID 9409700 DOI: 10.1016/S0006-8993(97)00818-4  0.715
1997 Orlando LR, Luthi-Carter R, Standaert DG, Coyle JT, Penney JB, Young AB. N-acetylaspartylglutamate (NAAG) protects against rat striatal quinolinic acid lesions in vivo. Neuroscience Letters. 236: 91-4. PMID 9404819 DOI: 10.1016/S0304-3940(97)00769-6  0.637
1997 Sapp E, Schwarz C, Chase K, Bhide PG, Young AB, Penney J, Vonsattel JP, Aronin N, DiFiglia M. Huntingtin localization in brains of normal and Huntington's disease patients. Annals of Neurology. 42: 604-12. PMID 9382472 DOI: 10.1002/Ana.410420411  0.495
1997 Wüllner U, Standaert DG, Testa CM, Penney JB, Young AB. Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain. Brain Research. 768: 215-23. PMID 9369318 DOI: 10.1016/S0006-8993(97)00645-8  0.776
1997 Kerner JA, Standaert DG, Penney JB, Young AB, Landwehrmeyer GB. Expression of group one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus. Brain Research. Molecular Brain Research. 48: 259-69. PMID 9332723 DOI: 10.1016/S0169-328X(97)00102-2  0.656
1997 Scherzer CR, Landwehrmeyer GB, Kerner JA, Standaert DG, Hollingsworth ZR, Daggett LP, Veliçelebi G, Penney JB, Young AB. Cellular distribution of NMDA glutamate receptor subunit mRNAs in the human cerebellum. Neurobiology of Disease. 4: 35-46. PMID 9258910 DOI: 10.1006/nbdi.1997.0136  0.661
1997 Kosinski CM, Cha JH, Young AB, Persichetti F, MacDonald M, Gusella JF, Penney JB, Standaert DG. Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons. Experimental Neurology. 144: 239-47. PMID 9168825 DOI: 10.1006/Exnr.1997.6441  0.629
1996 Standaert DG, Landwehrmeyer GB, Kerner JA, Penney JB, Young AB. Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus. Brain Research. Molecular Brain Research. 42: 89-102. PMID 8915584 DOI: 10.1016/S0169-328X(96)00117-9  0.676
1996 Rudolf GD, Cronin CA, Landwehrmeyer GB, Standaert DG, Penney JB, Young AB. Expression of N-methyl-D-aspartate glutamate receptor subunits in the prefrontal cortex of the rat. Neuroscience. 73: 417-27. PMID 8783259 DOI: 10.1016/0306-4522(96)00048-6  0.653
1996 Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M. Expression of normal and mutant huntingtin in the developing brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5523-35. PMID 8757264 DOI: 10.1523/Jneurosci.16-17-05523.1996  0.483
1996 Penney JB, Standaert DG, Testa CM, Landwehrmeyer GB, Young AB. Glutamate receptor genes in Parkinson's disease. Advances in Neurology. 69: 79-86. PMID 8615188  0.753
1995 Orlando LR, Standaert DG, Penney JB, Young AB. Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neuroscience Letters. 202: 109-12. PMID 8787843 DOI: 10.1016/0304-3940(95)12219-2  0.648
1995 Landwehrmeyer GB, McNeil SM, Dure IV LS, Ge P, Aizawa H, Huang Q, Ambrose CM, Duyao MP, Bird ED, Bonilla E, De Young M, Avila-Gonzales AJ, Wexler NS, DiFiglia M, Gusella JF, ... ... Penney JB, et al. Huntington's disease gene: Regional and cellular expression in brain of normal and affected individuals Annals of Neurology. 37: 218-230. PMID 7847863 DOI: 10.1002/Ana.410370213  0.506
1995 Testa CM, Standaert DG, Landwehrmeyer GB, Penney JB, Young AB. Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons. The Journal of Comparative Neurology. 354: 241-52. PMID 7782501 DOI: 10.1002/cne.903540207  0.768
1995 Landwehrmeyer GB, Standaert DG, Testa CM, Penney JB, Young AB. NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5297-307. PMID 7623152 DOI: 10.1523/Jneurosci.15-07-05297.1995  0.783
1995 Aronin N, Chase K, Young C, Sapp E, Schwarz C, Matta N, Kornreich R, Lanwehrmeyer B, Bird E, Beal MF, Vonsattel JP, Smith T, Carraway R, Boyce FM, Young AB, ... Penney JB, et al. CAG expansion affects the expression of mutant huntingtin in the Huntington's disease brain Neuron. 15: 1193-1201. PMID 7576661 DOI: 10.1016/0896-6273(95)90106-X  0.44
1995 Albin RL, Young AB, Penney JB. The functional anatomy of disorders of the basal ganglia. Trends in Neurosciences. 18: 63-4. PMID 7537410 DOI: 10.1016/0166-2236(95)80020-3  0.374
1995 Sapp E, Ge P, Aizawa H, Bird E, Penney J, Young AB, Vonsattel JP, DiFiglia M. Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis. Neuroscience. 64: 397-404. PMID 7535402 DOI: 10.1016/0306-4522(94)00427-7  0.448
1994 Hyman BT, Penney JB, Blackstone CD, Young AB. Localization of non-N-methyl-D-aspartate glutamate receptors in normal and Alzheimer hippocampal formation. Annals of Neurology. 35: 31-7. PMID 8285589 DOI: 10.1002/Ana.410350106  0.556
1994 Catania MV, De Socarraz H, Penney JB, Young AB. Metabotropic glutamate receptor heterogeneity in rat brain. Molecular Pharmacology. 45: 626-36. PMID 8183241  0.576
1994 Testa CM, Standaert DG, Young AB, Penney JB. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3005-18. PMID 8182455 DOI: 10.1523/Jneurosci.14-05-03005.1994  0.792
1994 Arregui A, Hollingsworth Z, Penney JB, Young AB. Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice. Neuroscience Letters. 167: 195-7. PMID 8177524 DOI: 10.1016/0304-3940(94)91060-X  0.498
1994 Fotuhi M, Standaert DG, Testa CM, Penney JB, Young AB. Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat. Brain Research. Molecular Brain Research. 21: 283-92. PMID 8170352 DOI: 10.1016/0169-328X(94)90259-3  0.752
1994 Wüllner U, Testa CM, Catania MV, Young AB, Penney JB. Glutamate receptors in striatum and substantia nigra: effects of medial forebrain bundle lesions. Brain Research. 645: 98-102. PMID 8062103 DOI: 10.1016/0006-8993(94)91642-X  0.739
1994 Standaert DG, Testa CM, Young AB, Penney JB. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. The Journal of Comparative Neurology. 343: 1-16. PMID 8027428 DOI: 10.1002/cne.903430102  0.794
1994 Catania MV, Landwehrmeyer GB, Testa CM, Standaert DG, Penney JB, Young AB. Metabotropic glutamate receptors are differentially regulated during development. Neuroscience. 61: 481-95. PMID 7969925 DOI: 10.1016/0306-4522(94)90428-6  0.785
1994 Wüllner U, Standaert DG, Testa CM, Landwehrmeyer GB, Catania MV, Penney JB, Young AB. Glutamate receptor expression in rat striatum: effect of deafferentation. Brain Research. 647: 209-19. PMID 7922497 DOI: 10.1016/0006-8993(94)91320-X  0.786
1994 Dure IV LS, Bernhard Landwehrmeyer G, Golden J, McNeil SM, Ge P, Aizawa H, Huang Q, Ambrose CM, Duyao MP, Bird ED, DiFiglia M, Gusella JF, MacDonald ME, Penney JB, Young AB, et al. IT15 gene expression in fetal human brain Brain Research. 659: 33-41. PMID 7820679 DOI: 10.1016/0006-8993(94)90860-5  0.453
1994 Wüllner U, Young AB, Penney JB, Beal MF. 3-Nitropropionic acid toxicity in the striatum. Journal of Neurochemistry. 63: 1772-81. PMID 7523600 DOI: 10.1046/j.1471-4159.1994.63051772.x  0.489
1993 Standaert DG, Testa CM, Penney JB, Young AB. Alternatively spliced isoforms of the NMDAR1 glutamate receptor subunit: differential expression in the basal ganglia of the rat. Neuroscience Letters. 152: 161-4. PMID 8515871 DOI: 10.1016/0304-3940(93)90508-I  0.766
1993 Wüllner U, Brouillet E, Isacson O, Young AB, Penney JB. Glutamate receptor binding sites in MPTP-treated mice. Experimental Neurology. 121: 284-7. PMID 8393409 DOI: 10.1006/exnr.1993.1098  0.568
1993 Price RH, Albin RL, Sakurai SY, Polinsky RJ, Penney JB, Young AB. Cerebellar excitatory and inhibitory amino acid receptors in multiple system atrophy. Neurology. 43: 1323-8. PMID 8392149 DOI: 10.1212/WNL.43.7.1323  0.538
1993 Holthoff VA, Koeppe RA, Frey KA, Penney JB, Markel DS, Kuhl DE, Young AB. Positron emission tomography measures of benzodiazepine receptors in Huntington's disease. Annals of Neurology. 34: 76-81. PMID 8390806 DOI: 10.1002/Ana.410340114  0.507
1993 Price RH, Hollingsworth Z, Young AB, Penney JB. Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat. Brain Research. 602: 157-60. PMID 8383570 DOI: 10.1016/0006-8993(93)90257-N  0.573
1993 Sakurai SY, Penney JB, Young AB. Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain. Journal of Neurochemistry. 60: 1344-53. PMID 8095974 DOI: 10.1111/j.1471-4159.1993.tb03295.x  0.575
1993 Carlson MD, Penney JB, Young AB. NMDA, AMPA, and benzodiazepine binding site changes in Alzheimer's disease visual cortex. Neurobiology of Aging. 14: 343-52. PMID 7690114 DOI: 10.1016/0197-4580(93)90120-Z  0.56
1993 Catania MV, Hollingsworth Z, Penney JB, Young AB. Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites. Neuroreport. 4: 311-3. PMID 7682857 DOI: 10.1097/00001756-199303000-00021  0.576
1993 Catania MV, Hollingsworth Z, Penney JB, Young AB. Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence. Journal of Neurochemistry. 60: 236-45. PMID 7678040 DOI: 10.1111/j.1471-4159.1993.tb05843.x  0.586
1992 Aldrich MS, Hollingsworth Z, Penney JB. Dopamine-receptor autoradiography of human narcoleptic brain. Neurology. 42: 410-5. PMID 1736175  0.308
1992 Kincaid AE, Albin RL, Newman SW, Penney JB, Young AB. 6-Hydroxydopamine lesions of the nigrostriatal pathway alter the expression of glutamate decarboxylase messenger RNA in rat globus pallidus projection neurons. Neuroscience. 51: 705-18. PMID 1488118 DOI: 10.1016/0306-4522(92)90309-P  0.511
1992 Dure LS, Young AB, Penney JB. Compartmentalization of excitatory amino acid receptors in human striatum. Proceedings of the National Academy of Sciences of the United States of America. 89: 7688-92. PMID 1380163 DOI: 10.1073/PNAS.89.16.7688  0.548
1992 Cha JH, Makowiec RL, Penney JB, Young AB. Multiple states of rat brain (RS)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors as revealed by quantitative autoradiography. Molecular Pharmacology. 41: 832-8. PMID 1375315  0.553
1992 Albin RL, Reiner A, Anderson KD, Dure LS, Handelin B, Balfour R, Whetsell WO, Penney JB, Young AB. Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Annals of Neurology. 31: 425-30. PMID 1375014 DOI: 10.1002/Ana.410310412  0.461
1992 Difazio MC, Hollingsworth Z, Young AB, Penney JB. Glutamate receptors in the substantia nigra of Parkinson's disease brains. Neurology. 42: 402-6. PMID 1346548 DOI: 10.1212/WNL.42.2.402  0.538
1992 Tallaksen-Greene SJ, Young AB, Penney JB, Beitz AJ. Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat. Neuroscience Letters. 141: 79-83. PMID 1324445 DOI: 10.1016/0304-3940(92)90339-9  0.526
1992 Albin RL, Makowiec RL, Hollingsworth ZR, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study. Neuroscience. 46: 35-48. PMID 1317515 DOI: 10.1016/0306-4522(92)90006-N  0.552
1991 Albin RL, Makowiec RL, Hollingsworth Z, Sakurai SY, Dure LS, Penney JB, Young AB. Excitatory amino acidergic pathways and receptors in the basal ganglia. Amino Acids. 1: 339-50. PMID 24194174 DOI: 10.1007/BF00814003  0.551
1991 Sakurai SY, Cha JH, Penney JB, Young AB. Regional distribution and properties of [3H]MK-801 binding sites determined by quantitative autoradiography in rat brain. Neuroscience. 40: 533-43. PMID 2027471 DOI: 10.1016/0306-4522(91)90139-F  0.528
1991 Kincaid AE, Penney JB, Young AB, Newman SW. The globus pallidus receives a projection from the parafascicular nucleus in the rat. Brain Research. 553: 18-26. PMID 1933274 DOI: 10.1016/0006-8993(91)90224-J  0.44
1991 Maragos WF, Greenamyre JT, Chu DC, Penney JB, Young AB. A study of cortical and hippocampal NMDA and PCP receptors following selective cortical and subcortical lesions. Brain Research. 538: 36-45. PMID 1850317 DOI: 10.1016/0006-8993(91)90373-4  0.725
1991 Albin RL, Qin Y, Young AB, Penney JB, Chesselet MF. Preproenkephalin messenger RNA-containing neurons in striatum of patients with symptomatic and presymptomatic Huntington's disease: an in situ hybridization study. Annals of Neurology. 30: 542-9. PMID 1838677 DOI: 10.1002/ana.410300406  0.486
1991 Albin RL, Price RH, Sakurai SY, Penney JB, Young AB. Excitatory and inhibitory amino acid binding sites in human dentate nucleus. Brain Research. 560: 350-3. PMID 1760743 DOI: 10.1016/0006-8993(91)91258-3  0.553
1991 Makowiec RL, Cha JJ, Penney JB, Young AB. Cerebellar excitatory amino acid binding sites in normal, granuloprival, and Purkinje cell-deficient mice. Neuroscience. 42: 671-81. PMID 1683473 DOI: 10.1016/0306-4522(91)90036-N  0.539
1991 Albin RL, Sakurai SY, Makowiec RL, Higgins DS, Young AB, Penney JB. Excitatory amino acid, GABA(A), and GABA(B) binding sites in human striate cortex. Cerebral Cortex (New York, N.Y. : 1991). 1: 499-509. PMID 1668367 DOI: 10.1093/Cercor/1.6.499  0.721
1991 Dure LS, Young AB, Penney JB. Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease. Annals of Neurology. 30: 785-93. PMID 1665055 DOI: 10.1002/ana.410300607  0.606
1991 Cha JH, Dure LS IV, Sakurai SY, Penney JB, Young AB. 2,4,5-Trihydroxyphenylalanine (6-hydroxy-dopa) displaces [3H]AMPA binding in rat striatum. Neuroscience Letters. 132: 55-8. PMID 1664920 DOI: 10.1016/0304-3940(91)90432-S  0.573
1991 Kincaid AE, Penney JB, Young AB, Newman SW. Evidence for a projection from the globus pallidus to the entopeduncular nucleus in the rat. Neuroscience Letters. 128: 121-5. PMID 1656332 DOI: 10.1016/0304-3940(91)90774-N  0.43
1990 Albin RL, Makowiec RL, Hollingsworth Z, Dure LS, Penney JB, Young AB. Excitatory amino acid binding sites in the periaqueductal gray of the rat. Neuroscience Letters. 118: 112-5. PMID 2175406 DOI: 10.1016/0304-3940(90)90261-7  0.538
1990 Greenamyre JT, Higgins DS, Young AB, Penney JB. Regional ontogeny of a unique glutamate recognition site in rat brain: an autoradiographic study. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 8: 437-45. PMID 2174635 DOI: 10.1016/0736-5748(90)90076-E  0.799
1990 McDonald JW, Penney JB, Johnston MV, Young AB. Characterization and regional distribution of strychnine-insensitive [3H]glycine binding sites in rat brain by quantitative receptor autoradiography. Neuroscience. 35: 653-68. PMID 2166246 DOI: 10.1016/0306-4522(90)90336-3  0.661
1990 Penney JB, Maragos WF, Greenamyre JT, Debowey DL, Hollingsworth Z, Young AB. Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias. Journal of Neurology, Neurosurgery, and Psychiatry. 53: 314-20. PMID 2160518 DOI: 10.1136/jnnp.53.4.314  0.712
1990 Chu DC, Albin RL, Young AB, Penney JB. Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study. Neuroscience. 34: 341-57. PMID 2159128 DOI: 10.1016/0306-4522(90)90144-S  0.548
1990 Penney JB, Young AB, Shoulson I, Starosta-Rubenstein S, Snodgrass SR, Sanchez-Ramos J, Ramos-Arroyo M, Gomez F, Penchaszadeh G, Alvir J. Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals. Movement Disorders : Official Journal of the Movement Disorder Society. 5: 93-9. PMID 2139171 DOI: 10.1002/Mds.870050202  0.381
1990 Young AB, Dauth GW, Hollingsworth Z, Penney JB, Kaatz K, Gilman S. Quisqualate- and NMDA-sensitive [3H]glutamate binding in primate brain. Journal of Neuroscience Research. 27: 512-21. PMID 1981916 DOI: 10.1002/Jnr.490270412  0.587
1990 Cha JH, Makowiec RL, Penney JB, Young AB. L-[3H]glutamate labels the metabotropic excitatory amino acid receptor in rodent brain. Neuroscience Letters. 113: 78-83. PMID 1973276 DOI: 10.1016/0304-3940(90)90498-X  0.591
1990 Albin RL, Reiner A, Anderson KD, Penney JB, Young AB. Striatal and nigral neuron subpopulations in rigid Huntington's disease: implications for the functional anatomy of chorea and rigidity-akinesia. Annals of Neurology. 27: 357-65. PMID 1972318 DOI: 10.1002/Ana.410270403  0.483
1990 Albin RL, Young AB, Penney JB, Handelin B, Balfour R, Anderson KD, Markel DS, Tourtellotte WW, Reiner A. Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease. The New England Journal of Medicine. 322: 1293-8. PMID 1691447 DOI: 10.1056/Nejm199005033221807  0.493
1989 Irwin CC, Wexler NS, Young AB, Ozelius LJ, Penney JB, Shoulson I, Snodgrass SR, Ramos-Arroyo MA, Sanchez-Ramos J, Penchaszadeh GK. The role of mitochondrial DNA in Huntington's disease. Journal of Molecular Neuroscience : Mn. 1: 129-36. PMID 2534902 DOI: 10.1007/Bf02896896  0.389
1989 Richfield EK, Penney JB, Young AB. Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system. Neuroscience. 30: 767-77. PMID 2528080 DOI: 10.1016/0306-4522(89)90168-1  0.497
1989 Richfield EK, Young AB, Penney JB. Comparative distributions of dopamine D-1 and D-2 receptors in the cerebral cortex of rats, cats, and monkeys. The Journal of Comparative Neurology. 286: 409-26. PMID 2506254 DOI: 10.1002/Cne.902860402  0.508
1989 Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends in Neurosciences. 12: 366-75. PMID 2479133 DOI: 10.1016/0166-2236(89)90074-X  0.468
1988 Olson JM, Junck L, Young AB, Penney JB, Mancini WR. Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging. Cancer Research. 48: 5837-41. PMID 3262414  0.459
1988 Berent S, Giordani B, Lehtinen S, Markel D, Penney JB, Buchtel HA, Starosta-Rubinstein S, Hichwa R, Young AB. Positron emission tomographic scan investigations of Huntington's disease: cerebral metabolic correlates of cognitive function. Annals of Neurology. 23: 541-6. PMID 2970247 DOI: 10.1002/Ana.410230603  0.397
1988 Nielsen EO, Cha JH, Honoré T, Penney JB, Young AB. Thiocyanate stabilizes AMPA binding to the quisqualate receptor. European Journal of Pharmacology. 157: 197-203. PMID 2906292 DOI: 10.1016/0014-2999(88)90383-4  0.525
1988 Greenamyre JT, Maragos WF, Albin RL, Penney JB, Young AB. Glutamate transmission and toxicity in Alzheimer's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: 421-30. PMID 2900537 DOI: 10.1016/0278-5846(88)90102-9  0.655
1988 Cha JH, Greenamyre JT, Nielsen EO, Penney JB, Young AB. Properties of quisqualate-sensitive L-[3H]glutamate binding sites in rat brain as determined by quantitative autoradiography. Journal of Neurochemistry. 51: 469-78. PMID 2899133 DOI: 10.1111/J.1471-4159.1988.Tb01062.X  0.677
1988 Young AB, Greenamyre JT, Hollingsworth Z, Albin R, D'Amato C, Shoulson I, Penney JB. NMDA receptor losses in putamen from patients with Huntington's disease. Science (New York, N.Y.). 241: 981-3. PMID 2841762 DOI: 10.1126/Science.2841762  0.715
1988 Richfield EK, Ciliax BJ, Starosta-Rubinstein SR, McKeever PE, Penney JB, Young AB. Comparison of [14C]-deoxyglucose metabolism and peripheral benzodiazepine receptor binding in rat C6 glioma. Neurology. 38: 1255-62. PMID 2840604 DOI: 10.1212/Wnl.38.8.1255  0.445
1988 Albin RL, Young AB, Penney JB. Tetrahydro-9-aminoacridine (THA) interacts with the phencyclidine (PCP) receptor site. Neuroscience Letters. 88: 303-7. PMID 2838771 DOI: 10.1016/0304-3940(88)90228-5  0.504
1988 Maragos WF, Penney JB, Young AB. Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 493-501. PMID 2828564 DOI: 10.1523/Jneurosci.08-02-00493.1988  0.578
1988 Reiner A, Albin RL, Anderson KD, D'Amato CJ, Penney JB, Young AB. Differential loss of striatal projection neurons in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 85: 5733-7. PMID 2456581 DOI: 10.1073/Pnas.85.15.5733  0.46
1987 Maragos WF, Chu DC, Young AB, D'Amato CJ, Penney JB. Loss of hippocampal [3H]TCP binding in Alzheimer's disease. Neuroscience Letters. 74: 371-6. PMID 3031556 DOI: 10.1016/0304-3940(87)90326-0  0.539
1987 Starosta-Rubinstein S, Ciliax BJ, Penney JB, McKeever P, Young AB. Imaging of a glioma using peripheral benzodiazepine receptor ligands. Proceedings of the National Academy of Sciences of the United States of America. 84: 891-5. PMID 3027710 DOI: 10.1073/Pnas.84.3.891  0.489
1987 Richfield EK, Young AB, Penney JB. Comparative distribution of dopamine D-1 and D-2 receptors in the basal ganglia of turtles, pigeons, rats, cats, and monkeys. The Journal of Comparative Neurology. 262: 446-63. PMID 2958517 DOI: 10.1002/Cne.902620308  0.511
1987 Richfield EK, Debowey DL, Penney JB, Young AB. Basal ganglia and cerebral cortical distribution of dopamine D1- and D2-receptors in neonatal and adult cat brain. Neuroscience Letters. 73: 203-8. PMID 2951618 DOI: 10.1016/0304-3940(87)90245-X  0.507
1987 Young AB, Penney JB, Starosta-Rubinstein S, Markel D, Berent S, Rothley J, Betley A, Hichwa R. Normal caudate glucose metabolism in persons at risk for Huntington's disease. Archives of Neurology. 44: 254-7. PMID 2950844 DOI: 10.1001/Archneur.1987.00520150010010  0.38
1987 Markel DS, Young AB, Penney JB. At-risk persons' attitudes toward presymptomatic and prenatal testing of Huntington disease in Michigan. American Journal of Medical Genetics. 26: 295-305. PMID 2949613 DOI: 10.1002/ajmg.1320260207  0.362
1987 Bromberg MB, Pamel G, Stephenson BS, Young AB, Penney JB. Evidence for reactive synaptogenesis in the ventrolateral thalamus and red nucleus of the rat: changes in high affinity glutamate uptake and numbers of corticofugal fiber terminals. Experimental Brain Research. 69: 53-9. PMID 2893742 DOI: 10.1007/Bf00247028  0.481
1987 Olson JM, Greenamyre JT, Penney JB, Young AB. Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse. Neuroscience. 22: 913-23. PMID 2891079 DOI: 10.1016/0306-4522(87)92969-1  0.644
1987 Greenamyre T, Penney JB, Young AB, Hudson C, Silverstein FS, Johnston MV. Evidence for transient perinatal glutamatergic innervation of globus pallidus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1022-30. PMID 2883265 DOI: 10.1523/Jneurosci.07-04-01022.1987  0.654
1987 Wexler NS, Young AB, Tanzi RE, Travers H, Starosta-Rubinstein S, Penney JB, Snodgrass SR, Shoulson I, Gomez F, Ramos Arroyo MA. Homozygotes for Huntington's disease. Nature. 326: 194-7. PMID 2881213 DOI: 10.1038/326194A0  0.414
1987 Greenamyre JT, Penney JB, D'Amato CJ, Young AB. Dementia of the Alzheimer's type: changes in hippocampal L-[3H]glutamate binding. Journal of Neurochemistry. 48: 543-51. PMID 2878980 DOI: 10.1111/J.1471-4159.1987.Tb04127.X  0.72
1987 Chu DC, Penney JB, Young AB. Quantitative autoradiography of hippocampal GABAB and GABAA receptor changes in Alzheimer's disease. Neuroscience Letters. 82: 246-52. PMID 2827074 DOI: 10.1016/0304-3940(87)90264-3  0.516
1987 Chu DC, Penney JB, Young AB. Cortical GABAB and GABAA receptors in Alzheimer's disease: a quantitative autoradiographic study. Neurology. 37: 1454-9. PMID 2819782 DOI: 10.1212/WNL.37.9.1454  0.538
1986 Richfield EK, Young AB, Penney JB. Properties of D2 dopamine receptor autoradiography: high percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections. Brain Research. 383: 121-8. PMID 3768686 DOI: 10.1016/0006-8993(86)90013-2  0.543
1986 Ciliax BJ, Penney JB, Young AB. In vivo [3H]flunitrazepam binding: imaging of receptor regulation. The Journal of Pharmacology and Experimental Therapeutics. 238: 749-57. PMID 3016249  0.52
1986 Maragos WF, Chu DC, Greenamyre JT, Penney JB, Young AB. High correlation between the localization of [3H]TCP binding and NMDA receptors. European Journal of Pharmacology. 123: 173-4. PMID 3011454 DOI: 10.1016/0014-2999(86)90703-X  0.695
1986 Young AB, Penney JB, Starosta-Rubinstein S, Markel DS, Berent S, Giordani B, Ehrenkaufer R, Jewett D, Hichwa R. PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional decline. Annals of Neurology. 20: 296-303. PMID 2945510 DOI: 10.1002/Ana.410200305  0.381
1986 Young AB, Shoulson I, Penney JB, Starosta-Rubinstein S, Gomez F, Travers H, Ramos-Arroyo MA, Snodgrass SR, Bonilla E, Moreno H. Huntington's disease in Venezuela: neurologic features and functional decline. Neurology. 36: 244-9. PMID 2935747 DOI: 10.1212/WNL.36.2.244  0.391
1986 Penney JB, Young AB. Striatal inhomogeneities and basal ganglia function. Movement Disorders : Official Journal of the Movement Disorder Society. 1: 3-15. PMID 2848190 DOI: 10.1002/mds.870010102  0.425
1985 Johnston MV, Silverstein FS, Reindel FO, Penney JB, Young AB. Muscarinic cholinergic receptors in human infant forebrain: [3H]quinuclidinyl benzilate binding in homogenates and quantitative autoradiography in sections. Brain Research. 351: 195-203. PMID 3995346 DOI: 10.1016/0165-3806(85)90191-9  0.617
1985 Pan HS, Penney JB, Young AB. Gamma-aminobutyric acid and benzodiazepine receptor changes induced by unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. Journal of Neurochemistry. 45: 1396-404. PMID 2995585 DOI: 10.1111/j.1471-4159.1985.tb07205.x  0.488
1985 Greenamyre JT, Olson JM, Penney JB, Young AB. Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites. The Journal of Pharmacology and Experimental Therapeutics. 233: 254-63. PMID 2984415  0.687
1985 Greenamyre JT, Penney JB, Young AB, D'Amato CJ, Hicks SP, Shoulson I. Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases. Science (New York, N.Y.). 227: 1496-9. PMID 2858129 DOI: 10.1126/Science.2858129  0.69
1984 Pan HS, Dauth GW, Young AB, Penney JB. Computer-assisted estimates of lesion sizes and shrinkage in denervated areas from receptor autoradiograms using a digitizing tablet. Neuroscience Letters. 44: 277-80. PMID 6728297 DOI: 10.1016/0304-3940(84)90035-1  0.41
1984 Young AB, Penney JB. Neurochemical anatomy of movement disorders. Neurologic Clinics. 2: 417-33. PMID 6152481 DOI: 10.1016/S0733-8619(18)31082-X  0.419
1984 Pan HS, Penney JB, Young AB. Characterization of benzodiazepine receptor changes in substantia nigra, globus pallidus and entopeduncular nucleus after striatal lesions. The Journal of Pharmacology and Experimental Therapeutics. 230: 768-75. PMID 6147405  0.538
1984 Abou-Khalil B, Young AB, Penney JB. Evidence for the presynaptic localization of opiate binding sites on striatal efferent fibers. Brain Research. 323: 21-9. PMID 6098334 DOI: 10.1016/0006-8993(84)90261-0  0.518
1984 Young AB, Pan HS, Ciliax BJ, Penney JB. GABA and benzodiazepine receptors in basal ganglia function. Neuroscience Letters. 47: 361-7. PMID 6089057 DOI: 10.1016/0304-3940(84)90540-8  0.504
1984 Greenamyre JT, Young AB, Penney JB. Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 2133-44. PMID 6088729 DOI: 10.1523/Jneurosci.04-08-02133.1984  0.687
1984 Walker FO, Young AB, Penney JB, Dovorini-Zis K, Shoulson I. Benzodiazepine and GABA receptors in early Huntington's disease. Neurology. 34: 1237-40. PMID 6087209 DOI: 10.1212/WNL.34.9.1237  0.519
1983 Penney JB, Young AB. Speculations on the functional anatomy of basal ganglia disorders. Annual Review of Neuroscience. 6: 73-94. PMID 6838141 DOI: 10.1146/annurev.ne.06.030183.000445  0.376
1983 Pan HS, Frey KA, Young AB, Penney JB. Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 1189-98. PMID 6304260 DOI: 10.1523/Jneurosci.03-06-01189.1983  0.561
1983 Young AB, Penney JB, Dauth GW, Bromberg MB, Gilman S. Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey. Neurology. 33: 1513-6. PMID 6138734 DOI: 10.1212/Wnl.33.11.1513  0.488
1983 Greenamyre JT, Young AB, Penney JB. Quantitative autoradiography of L-[3H]glutamate binding to rat brain. Neuroscience Letters. 37: 155-60. PMID 6136011 DOI: 10.1016/0304-3940(83)90146-5  0.688
1982 Penney JB, Young AB. Quantitative autoradiography of neurotransmitter receptors in Huntington disease. Neurology. 32: 1391-5. PMID 6292789 DOI: 10.1212/WNL.32.12.1391  0.539
1981 Penney JB, Pan HS, Young AB, Frey KA, Dauth GW. Quantitative autoradiography of [3H]muscimol binding in rat brain. Science (New York, N.Y.). 214: 1036-8. PMID 6272394 DOI: 10.1126/Science.6272394  0.52
1981 Penney JB, Frey K, Young AB. Quantitative autoradiography of neurotransmitter receptors using tritium-sensitive film. European Journal of Pharmacology. 72: 421-2. PMID 6268430 DOI: 10.1016/0014-2999(81)90591-4  0.436
1981 Penney JB, Young AB. GABA as the pallidothalamic neurotransmitter: implications for basal ganglia function. Brain Research. 207: 195-9. PMID 6258730 DOI: 10.1016/0006-8993(81)90693-4  0.444
1981 Bromberg MB, Penney JB, Stephenson BS, Young AB. Evidence for glutamate as the neurotransmitter of corticothalamic and corticorubral pathways. Brain Research. 215: 369-74. PMID 6167322 DOI: 10.1016/0006-8993(81)90519-9  0.475
1973 Weiner LP, Narayan O, Penney JB, Herndon RM, Feringa ER, Tourtellotte WW, Johnson RT. Papovavirus of JC type in progressive multifocal leukoencephalopathy. Rapid identification and subsequent isolation. Archives of Neurology. 29: 1-3. PMID 4576212 DOI: 10.1001/Archneur.1973.00490250019001  0.551
1973 Narayan O, Penney JB, Johnson RT, Herndon RM, Weiner LP. Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus. The New England Journal of Medicine. 289: 1278-82. PMID 4356147 DOI: 10.1056/Nejm197312132892405  0.554
1973 Penney JB, Narayan O. Studies of the antigenic relationships of the new human papovaviruses by electron microscopy agglutination. Infection and Immunity. 8: 299-300. PMID 4353543 DOI: 10.1128/Iai.8.2.299-300.1973  0.368
1972 Penney JB, Weiner LP, Herndon RM, Narayan O, Johnson RT. Virions from progressive multifocal leukoencephalopathy: rapid serological identification by electron microscopy. Science (New York, N.Y.). 178: 60-2. PMID 4341819 DOI: 10.1126/Science.178.4056.60  0.539
Show low-probability matches.