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Peter B. Dervan - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
DNA recognition
Website:
http://dervan.caltech.edu/dervan.html
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Year Citation  Score
2022 Oh J, Jia T, Xu J, Chong J, Dervan PB, Wang D. RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35022237 DOI: 10.1073/pnas.2114065119  0.311
2020 Chen CY, Li Y, Jia T, He L, Hare AA, Silberstein A, Gallagher J, Martinez TF, Stiles JW, Olenyuk B, Dervan PB, Stiles BL. Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides. Medicinal Chemistry Research : An International Journal For Rapid Communications On Design and Mechanisms of Action of Biologically Active Agents. 29: 607-616. PMID 34552311 DOI: 10.1007/s00044-019-02493-4  0.704
2020 Finn PB, Bhimsaria D, Ali A, Eguchi A, Ansari AZ, Dervan PB. Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome. Plos One. 15: e0243905. PMID 33351840 DOI: 10.1371/journal.pone.0243905  0.464
2020 Chen C, Li Y, Jia T, He L, Hare AA, Silberstein A, Gallagher J, Martinez TF, Stiles JW, Olenyuk B, Dervan PB, Stiles BL. Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides Medicinal Chemistry Research. 29: 607-616. DOI: 10.1007/S00044-019-02493-4  0.727
2019 Kurmis AA, Dervan PB. Sequence specific suppression of androgen receptor-DNA binding in vivo by a Py-Im polyamide. Nucleic Acids Research. PMID 30838415 DOI: 10.1093/Nar/Gkz153  0.455
2019 Dervan PB. A Personal Perspective on Chemical Biology: Before the Beginning Israel Journal of Chemistry. 59: 71-83. DOI: 10.1002/Ijch.201800171  0.443
2018 Diaz-Perez S, Kane N, Kurmis AA, Yang F, Kummer NT, Dervan PB, Nickols NG. Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide. Plos One. 13: e0196803. PMID 29715291 DOI: 10.1371/Journal.Pone.0196803  0.682
2018 Diaz-Perez S, Kane N, Yang F, Kurmis A, Kummer N, Dervan P, Nickols N. Radiosensitization by a Pyrrole-Imidazole Polyamide Through Interference with DNA Repair International Journal of Radiation Oncology*Biology*Physics. 102: e155. DOI: 10.1016/J.Ijrobp.2018.07.604  0.743
2018 Houk KN, Caserio MC, Whitesides GM, Schuster DI, Dervan PB, Dougherty DA. J. D. Roberts Special Issue Journal of Physical Organic Chemistry. 31: e3886. DOI: 10.1002/Poc.3886  0.326
2017 Xu J, Lahiri I, Wang W, Wier A, Cianfrocco MA, Chong J, Hare AA, Dervan PB, DiMaio F, Leschziner AE, Wang D. Structural basis for the initiation of eukaryotic transcription-coupled DNA repair. Nature. PMID 29168508 DOI: 10.1038/Nature24658  0.383
2017 Kurmis AA, Yang F, Welch TR, Nickols NG, Dervan PB. A pyrrole-imidazole polyamide is active against enzalutamide-resistant prostate cancer. Cancer Research. PMID 28360139 DOI: 10.1158/0008-5472.Can-16-2503  0.657
2016 Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D. RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791148 DOI: 10.1073/Pnas.1612745113  0.674
2016 Gerhardt J, Bhalla AD, Butler JS, Puckett JW, Dervan PB, Rosenwaks Z, Napierala M. Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells. Cell Reports. PMID 27425605 DOI: 10.1016/J.Celrep.2016.06.075  0.837
2016 Mysore VS, Szablowski J, Dervan PB, Frost PJ. A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma has Potent Anti-tumor Activity. Molecular Cancer Research : McR. PMID 26801054 DOI: 10.1158/1541-7786.Mcr-15-0361  0.789
2015 Szablowski JO, Raskatov JA, Dervan PB. An HRE-binding Py-Im polyamide impairs hypoxic signaling in tumors. Molecular Cancer Therapeutics. PMID 26719577 DOI: 10.1158/1535-7163.Mct-15-0719  0.785
2015 Hargrove AE, Martinez TF, Hare AA, Kurmis AA, Phillips JW, Sud S, Pienta KJ, Dervan PB. Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. Plos One. 10: e0143161. PMID 26571387 DOI: 10.1371/Journal.Pone.0143161  0.835
2015 Kang JS, Dervan PB. A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma. Quarterly Reviews of Biophysics. 48: 453-64. PMID 26537405 DOI: 10.1017/S0033583515000104  0.448
2015 Kummer N, Yang F, Dervan P, Nickols N. Radiosensitization by DNA, Binding Pyrrole, Imidazole Polyamides International Journal of Radiation Oncology*Biology*Physics. 93: E537-E538. DOI: 10.1016/J.Ijrobp.2015.07.1923  0.76
2014 Martínez TF, Phillips JW, Karanja KK, Polaczek P, Wang CM, Li BC, Campbell JL, Dervan PB. Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response. Nucleic Acids Research. 42: 11546-59. PMID 25249630 DOI: 10.1093/Nar/Gku866  0.753
2014 Raskatov JA, Szablowski JO, Dervan PB. Tumor xenograft uptake of a pyrrole-imidazole (Py-Im) polyamide varies as a function of cell line grafted. Journal of Medicinal Chemistry. 57: 8471-6. PMID 25238175 DOI: 10.1021/Jm500964C  0.788
2014 Raskatov JA, Puckett JW, Dervan PB. A C-14 labeled Py-Im polyamide localizes to a subcutaneous prostate cancer tumor. Bioorganic & Medicinal Chemistry. 22: 4371-5. PMID 24780272 DOI: 10.1016/J.Bmc.2014.04.010  0.768
2014 Kang JS, Meier JL, Dervan PB. Design of sequence-specific DNA binding molecules for DNA methyltransferase inhibition. Journal of the American Chemical Society. 136: 3687-94. PMID 24502234 DOI: 10.1021/Ja500211Z  0.718
2014 Mysore VS, Nickols NG, Szablowski J, Dervan P, Lichtenstein A, Frost PJ. Abstract 5132: Targeting hypoxia-mediated gene transcription with a novel polyamide drug designed to disrupt the HIF1α/β heterodimer binding overcomes resistance to hypoxia in myeloma cell lines Cancer Research. 74: 5132-5132. DOI: 10.1158/1538-7445.Am2014-5132  0.793
2013 Yang F, Nickols NG, Li BC, Szablowski JO, Hamilton SR, Meier JL, Wang CM, Dervan PB. Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit. Journal of Medicinal Chemistry. 56: 7449-57. PMID 24015881 DOI: 10.1021/Jm401100S  0.772
2013 Nickols NG, Szablowski JO, Hargrove AE, Li BC, Raskatov JA, Dervan PB. Activity of a Py-Im polyamide targeted to the estrogen response element. Molecular Cancer Therapeutics. 12: 675-84. PMID 23443804 DOI: 10.1158/1535-7163.Mct-12-1040  0.814
2013 Edwards JS, Betts L, Frazier ML, Pollet RM, Kwong SM, Walton WG, Ballentine WK, Huang JJ, Habibi S, Del Campo M, Meier JL, Dervan PB, Firth N, Redinbo MR. Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 110: 2804-9. PMID 23359708 DOI: 10.1073/Pnas.1219701110  0.606
2013 Yang F, Nickols NG, Li BC, Marinov GK, Said JW, Dervan PB. Antitumor activity of a pyrrole-imidazole polyamide. Proceedings of the National Academy of Sciences of the United States of America. 110: 1863-8. PMID 23319609 DOI: 10.1073/Pnas.1222035110  0.786
2013 Li BC, Montgomery DC, Puckett JW, Dervan PB. Synthesis of cyclic Py-Im polyamide libraries. The Journal of Organic Chemistry. 78: 124-33. PMID 23106218 DOI: 10.1021/Jo302053V  0.835
2013 Chenoweth DM, Meier JL, Dervan PB. Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA. Angewandte Chemie (International Ed. in English). 52: 415-8. PMID 22987334 DOI: 10.1002/Anie.201205775  0.79
2013 Nickols NG, Yang F, Li BC, Szablowski JO, Wang C, Dervan PB. A second-generation DNA-binding pyrrole-imidazole polyamide with antitumor activity. Journal of Clinical Oncology. 31: e13588-e13588. DOI: 10.1200/Jco.2013.31.15_Suppl.E13588  0.811
2013 Nickols NG, Yang F, Li BC, Marinov GK, Said JW, Dervan PB. Abstract 1130: Antitumor activity of a pyrrole-imidazole polyamide in three tumor xenograft models. Cancer Research. 73: 1130-1130. DOI: 10.1158/1538-7445.Am2013-1130  0.716
2013 Nickols N, Yang F, Ratikan J, Li B, McBride W, Dervan P. Radiosensitization by High Affinity Programmable Minor Groove Binders International Journal of Radiation Oncology*Biology*Physics. 87: S651-S652. DOI: 10.1016/J.Ijrobp.2013.06.1725  0.767
2012 Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB. Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing. Journal of the American Chemical Society. 134: 17814-22. PMID 23013524 DOI: 10.1021/Ja308888C  0.727
2012 Raskatov JA, Nickols NG, Hargrove AE, Marinov GK, Wold B, Dervan PB. Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide. Proceedings of the National Academy of Sciences of the United States of America. 109: 16041-5. PMID 22988074 DOI: 10.1073/Pnas.1214267109  0.836
2012 Synold TW, Xi B, Wu J, Yen Y, Li BC, Yang F, Phillips JW, Nickols NG, Dervan PB. Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice. Cancer Chemotherapy and Pharmacology. 70: 617-25. PMID 22907527 DOI: 10.1007/S00280-012-1954-3  0.712
2012 Du J, Campau E, Soragni E, Ku S, Puckett JW, Dervan PB, Gottesfeld JM. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells. The Journal of Biological Chemistry. 287: 29861-72. PMID 22798143 DOI: 10.1074/Jbc.M112.391961  0.79
2012 Jespersen C, Soragni E, James Chou C, Arora PS, Dervan PB, Gottesfeld JM. Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells. Bioorganic & Medicinal Chemistry Letters. 22: 4068-71. PMID 22607671 DOI: 10.1016/J.Bmcl.2012.04.090  0.778
2012 Hargrove AE, Raskatov JA, Meier JL, Montgomery DC, Dervan PB. Characterization and solubilization of pyrrole-imidazole polyamide aggregates. Journal of Medicinal Chemistry. 55: 5425-32. PMID 22607187 DOI: 10.1021/Jm300380A  0.807
2012 Puckett JW, Green JT, Dervan PB. Microwave assisted synthesis of Py-Im polyamides. Organic Letters. 14: 2774-7. PMID 22578091 DOI: 10.1021/Ol3010003  0.778
2012 Raskatov JA, Hargrove AE, So AY, Dervan PB. Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear. Journal of the American Chemical Society. 134: 7995-9. PMID 22509786 DOI: 10.1021/Ja302588V  0.83
2012 Raskatov JA, Meier JL, Puckett JW, Yang F, Ramakrishnan P, Dervan PB. Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders. Proceedings of the National Academy of Sciences of the United States of America. 109: 1023-8. PMID 22203967 DOI: 10.1073/Pnas.1118506109  0.822
2012 Meier JL, Montgomery DC, Dervan PB. Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns. Nucleic Acids Research. 40: 2345-56. PMID 22080545 DOI: 10.1093/Nar/Gkr970  0.672
2011 Zhang Y, Sicot G, Cui X, Vogel M, Wuertzer CA, Lezon-Geyda K, Wheeler J, Harki DA, Muzikar KA, Stolper DA, Dervan PB, Perkins AS. Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide. Biochemistry. 50: 10431-41. PMID 22039883 DOI: 10.1021/Bi200962U  0.843
2011 Muzikar KA, Meier JL, Gubler DA, Raskatov JA, Dervan PB. Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA. Organic Letters. 13: 5612-5. PMID 21957930 DOI: 10.1021/Ol202285Y  0.853
2010 Chenoweth DM, Dervan PB. Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding. Journal of the American Chemical Society. 132: 14521-9. PMID 20812704 DOI: 10.1021/Ja105068B  0.761
2009 Muzikar KA, Nickols NG, Dervan PB. Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression. Proceedings of the National Academy of Sciences of the United States of America. 106: 16598-603. PMID 19805343 DOI: 10.1073/Pnas.0909192106  0.859
2009 Chenoweth DM, Dervan PB. Allosteric modulation of DNA by small molecules. Proceedings of the National Academy of Sciences of the United States of America. 106: 13175-9. PMID 19666554 DOI: 10.1073/Pnas.0906532106  0.742
2009 Chenoweth DM, Harki DA, Dervan PB. Oligomerization route to Py-Im polyamide macrocycles. Organic Letters. 11: 3590-3. PMID 19627138 DOI: 10.1021/Ol901311M  0.8
2009 Jacobs CS, Dervan PB. Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture. Journal of Medicinal Chemistry. 52: 7380-8. PMID 19572551 DOI: 10.1021/Jm900256F  0.622
2009 Ho D, Dose C, Albrecht CH, Severin P, Falter K, Dervan PB, Gaub HE. Quantitative detection of small molecule/DNA complexes employing a force-based and label-free DNA-microarray. Biophysical Journal. 96: 4661-71. PMID 19486688 DOI: 10.1016/J.Bpj.2009.02.059  0.491
2009 Chenoweth DM, Harki DA, Dervan PB. Solution-phase synthesis of pyrrole-imidazole polyamides. Journal of the American Chemical Society. 131: 7175-81. PMID 19413320 DOI: 10.1021/Ja901307M  0.79
2009 Chenoweth DM, Harki DA, Phillips JW, Dose C, Dervan PB. Cyclic pyrrole-imidazole polyamides targeted to the androgen response element. Journal of the American Chemical Society. 131: 7182-8. PMID 19413319 DOI: 10.1021/Ja901309Z  0.831
2009 Farkas ME, Li BC, Dose C, Dervan PB. DNA sequence selectivity of hairpin polyamide turn units. Bioorganic & Medicinal Chemistry Letters. 19: 3919-23. PMID 19349175 DOI: 10.1016/J.Bmcl.2009.03.072  0.791
2008 Harki DA, Satyamurthy N, Stout DB, Phelps ME, Dervan PB. In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 105: 13039-44. PMID 18753620 DOI: 10.1073/Pnas.0806308105  0.681
2008 Hsu CF, Dervan PB. Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cells. Bioorganic & Medicinal Chemistry Letters. 18: 5851-5. PMID 18524590 DOI: 10.1016/J.Bmcl.2008.05.063  0.563
2008 Dose C, Farkas ME, Chenoweth DM, Dervan PB. Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit. Journal of the American Chemical Society. 130: 6859-66. PMID 18459783 DOI: 10.1021/Ja800888D  0.785
2008 Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ. Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly. Acs Chemical Biology. 3: 220-9. PMID 18422304 DOI: 10.1021/Cb700258R  0.715
2008 Chou CJ, Farkas ME, Tsai SM, Alvarez D, Dervan PB, Gottesfeld JM. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia. Molecular Cancer Therapeutics. 7: 769-78. PMID 18413791 DOI: 10.1158/1535-7163.Mct-08-0130  0.781
2008 Cohen JD, Sadowski JP, Dervan PB. Programming multiple protein patterns on a single DNA nanostructure. Journal of the American Chemical Society. 130: 402-3. PMID 18081289 DOI: 10.1021/Ja0772400  0.694
2008 Sicot G, Vogel M, Zhang Y, Harki DA, Lezon-Geyda K, Dervan P, Perkins AS. Development of a Novel Polyamide-Based Agent to Inhibit EVI1 Function Blood. 112: 2660-2660. DOI: 10.1182/Blood.V112.11.2660.2660  0.691
2007 Hsu CF, Phillips JW, Trauger JW, Farkas ME, Belitsky JM, Heckel A, Olenyuk BZ, Puckett JW, Wang CC, Dervan PB. Completion of a Programmable DNA-Binding Small Molecule Library. Tetrahedron. 63: 6146-6151. PMID 18596841 DOI: 10.1016/J.Tet.2007.03.041  0.846
2007 Stafford RL, Dervan PB. The reach of linear protein-DNA dimerizers. Journal of the American Chemical Society. 129: 14026-33. PMID 17949089 DOI: 10.1021/Ja075247B  0.542
2007 Dose C, Ho D, Gaub HE, Dervan PB, Albrecht CH. Recognition of "mirror-image" DNA by small molecules. Angewandte Chemie (International Ed. in English). 46: 8384-7. PMID 17899583 DOI: 10.1002/Anie.200703007  0.457
2007 Puckett JW, Muzikar KA, Tietjen J, Warren CL, Ansari AZ, Dervan PB. Quantitative microarray profiling of DNA-binding molecules. Journal of the American Chemical Society. 129: 12310-9. PMID 17880081 DOI: 10.1021/Ja0744899  0.837
2007 Farkas ME, Tsai SM, Dervan PB. Alpha-diaminobutyric acid-linked hairpin polyamides. Bioorganic & Medicinal Chemistry. 15: 6927-36. PMID 17869122 DOI: 10.1016/J.Bmc.2007.07.019  0.717
2007 Cohen JD, Sadowski JP, Dervan PB. Addressing single molecules on DNA nanostructures. Angewandte Chemie (International Ed. in English). 46: 7956-9. PMID 17763481 DOI: 10.1002/Anie.200702767  0.677
2007 Nickols NG, Jacobs CS, Farkas ME, Dervan PB. Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface. Acs Chemical Biology. 2: 561-71. PMID 17708671 DOI: 10.1021/Cb700110Z  0.825
2007 Nickols NG, Dervan PB. Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide. Proceedings of the National Academy of Sciences of the United States of America. 104: 10418-23. PMID 17566103 DOI: 10.1073/Pnas.0704217104  0.672
2007 Stafford RL, Arndt HD, Brezinski ML, Ansari AZ, Dervan PB. Minimization of a protein-DNA dimerizer. Journal of the American Chemical Society. 129: 2660-8. PMID 17290996 DOI: 10.1021/Ja067971K  0.56
2007 Chenoweth DM, Viger A, Dervan PB. Fluorescent sequence-specific dsDNA binding oligomers. Journal of the American Chemical Society. 129: 2216-7. PMID 17279754 DOI: 10.1021/Ja0682576  0.734
2007 Nickols NG, Jacobs CS, Farkas ME, Dervan PB. Improved nuclear localization of DNA-binding polyamides. Nucleic Acids Research. 35: 363-70. PMID 17175539 DOI: 10.1093/Nar/Gkl1042  0.826
2007 Tsai SM, Farkas ME, Chou CJ, Gottesfeld JM, Dervan PB. Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates. Nucleic Acids Research. 35: 307-16. PMID 17170006 DOI: 10.1093/Nar/Gkl1025  0.786
2007 Chenoweth DM, Poposki JA, Marques MA, Dervan PB. Programmable oligomers targeting 5'-GGGG-3' in the minor groove of DNA and NF-kappaB binding inhibition. Bioorganic & Medicinal Chemistry. 15: 759-70. PMID 17095230 DOI: 10.1016/J.Bmc.2006.10.051  0.807
2007 Dervan PB, Urbach AR. The Importance of β-Alanine for Recognition of the Minor Groove of DNA Essays in Contemporary Chemistry: From Molecular Structure Towards Biology. 327-339. DOI: 10.1002/9783906390451.ch9  0.704
2006 Viger A, Dervan PB. Exploring the limits of benzimidazole DNA-binding oligomers for the hypoxia inducible factor (HIF) site. Bioorganic & Medicinal Chemistry. 14: 8539-49. PMID 16971129 DOI: 10.1016/J.Bmc.2006.08.028  0.432
2006 Alvarez D, Chou CJ, Latella L, Zeitlin SG, Ku S, Puri PL, Dervan PB, Gottesfeld JM. A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate. Cell Cycle (Georgetown, Tex.). 5: 1537-48. PMID 16861886 DOI: 10.4161/Cc.5.14.2913  0.712
2006 Burnett R, Melander C, Puckett JW, Son LS, Wells RD, Dervan PB, Gottesfeld JM. DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia. Proceedings of the National Academy of Sciences of the United States of America. 103: 11497-502. PMID 16857735 DOI: 10.1073/Pnas.0604939103  0.855
2006 Doss RM, Marques MA, Foister S, Chenoweth DM, Dervan PB. Programmable oligomers for minor groove DNA recognition. Journal of the American Chemical Society. 128: 9074-9. PMID 16834381 DOI: 10.1021/Ja0621795  0.845
2006 Warren CL, Kratochvil NC, Hauschild KE, Foister S, Brezinski ML, Dervan PB, Phillips GN, Ansari AZ. Defining the sequence-recognition profile of DNA-binding molecules. Proceedings of the National Academy of Sciences of the United States of America. 103: 867-72. PMID 16418267 DOI: 10.1073/Pnas.0509843102  0.842
2006 Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting Cancer Proliferation by Small-Molecule Gene Regulation (DOI:10.1016/j.chembiol.2004.09.004) Chemistry and Biology. 13: 339. DOI: 10.1016/J.Chembiol.2006.02.006  0.771
2005 Fechter EJ, Olenyuk B, Dervan PB. Sequence-specific fluorescence detection of DNA by polyamide-thiazole orange conjugates. Journal of the American Chemical Society. 127: 16685-91. PMID 16305259 DOI: 10.1021/Ja054650K  0.85
2005 Dervan PB, Doss RM, Marques MA. Programmable DNA binding oligomers for control of transcription. Current Medicinal Chemistry. Anti-Cancer Agents. 5: 373-87. PMID 16101489 DOI: 10.2174/1568011054222346  0.834
2005 Hauschild KE, Metzler RE, Arndt HD, Moretti R, Raffaelle M, Dervan PB, Ansari AZ. Temperature-sensitive protein-DNA dimerizers. Proceedings of the National Academy of Sciences of the United States of America. 102: 5008-13. PMID 15781856 DOI: 10.1073/Pnas.0501289102  0.537
2005 Gearhart MD, Dickinson L, Ehley J, Melander C, Dervan PB, Wright PE, Gottesfeld JM. Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides. Biochemistry. 44: 4196-203. PMID 15766247 DOI: 10.1021/Bi047872O  0.839
2005 Philips BJ, Chang AY, Dervan PB, Beerman TA. DNA damage effects of a polyamide-CBI conjugate in SV40 virions. Molecular Pharmacology. 67: 877-82. PMID 15576630 DOI: 10.1124/Mol.104.006254  0.678
2005 Edayathumangalam RS, Weyermann P, Dervan PB, Gottesfeld JM, Luger K. Nucleosomes in solution exist as a mixture of twist-defect states. Journal of Molecular Biology. 345: 103-14. PMID 15567414 DOI: 10.1016/J.Jmb.2004.10.012  0.761
2005 Dervan PB, Poulin-Kerstien AT, Fechter EJ, Edelson BS. Regulation of gene expression by synthetic DNA-binding ligands Topics in Current Chemistry. 253: 1-31. DOI: 10.1007/b100440  0.821
2004 Doss RM, Marques MA, Foister S, Dervan PB. DNA minor-groove recognition by 3-methylthiophene/pyrrole pair. Chemistry & Biodiversity. 1: 886-99. PMID 17191889 DOI: 10.1002/Cbdv.200490071  0.84
2004 Kwon Y, Arndt HD, Mao Q, Choi Y, Kawazoe Y, Dervan PB, Uesugi M. Small molecule transcription factor mimic. Journal of the American Chemical Society. 126: 15940-1. PMID 15584709 DOI: 10.1021/Ja0445140  0.447
2004 Olenyuk BZ, Zhang GJ, Klco JM, Nickols NG, Kaelin WG, Dervan PB. Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist. Proceedings of the National Academy of Sciences of the United States of America. 101: 16768-73. PMID 15556999 DOI: 10.1073/Pnas.0407617101  0.645
2004 Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting cancer proliferation by small-molecule gene regulation. Chemistry & Biology. 11: 1583-94. PMID 15556009 DOI: 10.1016/J.Chembiol.2004.09.004  0.799
2004 Ylisastigui L, Coull JJ, Rucker VC, Melander C, Bosch RJ, Brodie SJ, Corey L, Sodora DL, Dervan PB, Margolis DM. Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors. The Journal of Infectious Diseases. 190: 1429-37. PMID 15378435 DOI: 10.1086/423822  0.777
2004 Livengood JA, Fechter EJ, Dervan PB, Nyborg JK. Paradoxical effects of DNA binding polyamides on HTLV-1 transcription. Frontiers in Bioscience : a Journal and Virtual Library. 9: 3058-67. PMID 15353337 DOI: 10.2741/1459  0.841
2004 Marques MA, Doss RM, Foister S, Dervan PB. Expanding the repertoire of heterocycle ring pairs for programmable minor groove DNA recognition. Journal of the American Chemical Society. 126: 10339-49. PMID 15315448 DOI: 10.1021/Ja0486465  0.835
2004 Fechter EJ, Olenyuk B, Dervan PB. Design of a sequence-specific DNA bisintercalator. Angewandte Chemie (International Ed. in English). 43: 3591-4. PMID 15293255 DOI: 10.1002/Anie.200454231  0.848
2004 Zhang Q, Dwyer TJ, Tsui V, Case DA, Cho J, Dervan PB, Wemmer DE. NMR structure of a cyclic polyamide-DNA complex. Journal of the American Chemical Society. 126: 7958-66. PMID 15212545 DOI: 10.1021/Ja0373622  0.508
2004 Edelson BS, Best TP, Olenyuk B, Nickols NG, Doss RM, Foister S, Heckel A, Dervan PB. Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Nucleic Acids Research. 32: 2802-18. PMID 15155849 DOI: 10.1093/Nar/Gkh609  0.835
2004 Edayathumangalam RS, Weyermann P, Gottesfeld JM, Dervan PB, Luger K. Molecular recognition of the nucleosomal "supergroove". Proceedings of the National Academy of Sciences of the United States of America. 101: 6864-9. PMID 15100411 DOI: 10.1073/Pnas.0401743101  0.794
2004 Nguyen-Hackley DH, Ramm E, Taylor CM, Joung JK, Dervan PB, Pabo CO. Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands. Biochemistry. 43: 3880-90. PMID 15049695 DOI: 10.1021/Bi030223C  0.532
2004 Rucker VC, Dunn AR, Sharma S, Dervan PB, Gray HB. Mechanism of sequence-specific fluorescent detection of DNA by N-methyl-imidazole, N-methyl-pyrrole, and β-alanine linked polyamides Journal of Physical Chemistry B. 108: 7490-7494. DOI: 10.1021/Jp037423I  0.833
2003 Poulin-Kerstien AT, Dervan PB. DNA-templated dimerization of hairpin polyamides. Journal of the American Chemical Society. 125: 15811-21. PMID 14677972 DOI: 10.1021/Ja030494A  0.86
2003 Arndt HD, Hauschild KE, Sullivan DP, Lake K, Dervan PB, Ansari AZ. Toward artificial developmental regulators. Journal of the American Chemical Society. 125: 13322-3. PMID 14583004 DOI: 10.1021/Ja0371395  0.51
2003 Dudouet B, Burnett R, Dickinson LA, Wood MR, Melander C, Belitsky JM, Edelson B, Wurtz N, Briehn C, Dervan PB, Gottesfeld JM. Accessibility of nuclear chromatin by DNA binding polyamides. Chemistry & Biology. 10: 859-67. PMID 14522056 DOI: 10.1016/J.Chembiol.2003.09.001  0.85
2003 Best TP, Edelson BS, Nickols NG, Dervan PB. Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 100: 12063-8. PMID 14519850 DOI: 10.1073/Pnas.2035074100  0.811
2003 Foister S, Marques MA, Doss RM, Dervan PB. Shape selective recognition of T.A base pairs by hairpin polyamides containing N-terminal 3-methoxy (and 3-chloro) thiophene residues. Bioorganic & Medicinal Chemistry. 11: 4333-40. PMID 13129569 DOI: 10.1016/S0968-0896(03)00502-9  0.818
2003 Heckel A, Dervan PB. U-pin polyamide motif for recognition of the DNA minor groove. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 3353-66. PMID 12866079 DOI: 10.1002/Chem.200304784  0.716
2003 Fechter EJ, Dervan PB. Allosteric inhibition of protein--DNA complexes by polyamide--intercalator conjugates. Journal of the American Chemical Society. 125: 8476-85. PMID 12848553 DOI: 10.1021/Ja030125E  0.869
2003 Dervan PB, Edelson BS. Recognition of the DNA minor groove by pyrrole-imidazole polyamides. Current Opinion in Structural Biology. 13: 284-99. PMID 12831879 DOI: 10.1016/S0959-440X(03)00081-2  0.846
2003 Yang F, Belitsky JM, Villanueva RA, Dervan PB, Roth MJ. Inhibition of Moloney murine leukemia virus integration using polyamides targeting the long-terminal repeat sequences. Biochemistry. 42: 6249-58. PMID 12755629 DOI: 10.1021/Bi034177S  0.797
2003 Briehn CA, Weyermann P, Dervan PB. Alternative heterocycles for DNA recognition: the benzimidazole/imidazole pair. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 2110-22. PMID 12740860 DOI: 10.1002/Chem.200204689  0.582
2003 Renneberg D, Dervan PB. Imidazopyridine/Pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition. Journal of the American Chemical Society. 125: 5707-16. PMID 12733909 DOI: 10.1021/Ja0300158  0.439
2003 Olenyuk B, Jitianu C, Dervan PB. Parallel synthesis of H-pin polyamides by alkene metathesis on solid phase. Journal of the American Chemical Society. 125: 4741-51. PMID 12696892 DOI: 10.1021/Ja0213221  0.46
2003 Wang YD, Dziegielewski J, Wurtz NR, Dziegielewska B, Dervan PB, Beerman TA. DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate. Nucleic Acids Research. 31: 1208-15. PMID 12582240 DOI: 10.1093/Nar/Gkg215  0.82
2003 Suto RK, Edayathumangalam RS, White CL, Melander C, Gottesfeld JM, Dervan PB, Luger K. Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. Journal of Molecular Biology. 326: 371-80. PMID 12559907 DOI: 10.1016/S0022-2836(02)01407-9  0.823
2003 Rucker VC, Foister S, Melander C, Dervan PB. Sequence specific fluorescence detection of double strand DNA. Journal of the American Chemical Society. 125: 1195-202. PMID 12553822 DOI: 10.1021/Ja021011Q  0.845
2003 Rucker VC, Foister S, Melander C, Dervan PB. Sequence Specific Fluorescence Detection of Double Strand DNA  [J. Am. Chem. Soc.2003,125, 1195−1202]. Journal of the American Chemical Society. 125: 6008-6008. DOI: 10.1021/Ja033984B  0.827
2003 Rucker VC, Melander C, Dervan PB. Influence of β-alanine on hairpin polyamide orientation in the DNA minor groove Helvetica Chimica Acta. 86: 1839-1851. DOI: 10.1002/Hlca.200390148  0.821
2003 Heckel A, Dervan PB. Cover Picture: U-Pin Polyamide Motif for Recognition of the DNA Minor Groove (Chem. Eur. J. 14/2003) Chemistry - a European Journal. 9: 3173-3173. DOI: 10.1002/Chem.200390233  0.69
2002 Coull JJ, He G, Melander C, Rucker VC, Dervan PB, Margolis DM. Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides. Journal of Virology. 76: 12349-54. PMID 12414976 DOI: 10.1128/Jvi.76.23.12349-12354.2002  0.791
2002 Arora PS, Ansari AZ, Best TP, Ptashne M, Dervan PB. Design of artificial transcriptional activators with rigid poly-L-proline linkers. Journal of the American Chemical Society. 124: 13067-71. PMID 12405833 DOI: 10.1021/Ja0208355  0.836
2002 Hawkins CA, Baird EE, Dervan PB, Wemmer DE. Analysis of hairpin polyamide complexes having DNA binding sites in close proximity. Journal of the American Chemical Society. 124: 12689-96. PMID 12392416 DOI: 10.1021/Ja020335B  0.488
2002 Wang YD, Dziegielewski J, Chang AY, Dervan PB, Beerman TA. Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate. The Journal of Biological Chemistry. 277: 42431-7. PMID 12196541 DOI: 10.1074/Jbc.M207179200  0.714
2002 Kers I, Dervan PB. Search for the optimal linker in tandem hairpin polyamides. Bioorganic & Medicinal Chemistry. 10: 3339-49. PMID 12150881 DOI: 10.1016/S0968-0896(02)00221-3  0.365
2002 Belitsky JM, Leslie SJ, Arora PS, Beerman TA, Dervan PB. Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates. Bioorganic & Medicinal Chemistry. 10: 3313-8. PMID 12150878 DOI: 10.1016/S0968-0896(02)00204-3  0.826
2002 Gottesfeld JM, Belitsky JM, Melander C, Dervan PB, Luger K. Blocking transcription through a nucleosome with synthetic DNA ligands. Journal of Molecular Biology. 321: 249-63. PMID 12144782 DOI: 10.1016/S0022-2836(02)00598-3  0.844
2002 Urbach AR, Love JJ, Ross SA, Dervan PB. Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif. Journal of Molecular Biology. 320: 55-71. PMID 12079334 DOI: 10.1016/S0022-2836(02)00430-8  0.756
2002 Weyermann P, Dervan PB. Recognition of ten base pairs of DNA by head-to-head hairpin dimers. Journal of the American Chemical Society. 124: 6872-8. PMID 12059208 DOI: 10.1021/Ja020258K  0.475
2002 Belitsky JM, Nguyen DH, Wurtz NR, Dervan PB. Solid-phase synthesis of DNA binding polyamides on oxime resin. Bioorganic & Medicinal Chemistry. 10: 2767-74. PMID 12057666 DOI: 10.1016/S0968-0896(02)00133-5  0.839
2002 Wurtz NR, Pomerantz JL, Baltimore D, Dervan PB. Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides. Biochemistry. 41: 7604-9. PMID 12056891 DOI: 10.1021/Bi020114I  0.799
2002 Ehley JA, Melander C, Herman D, Baird EE, Ferguson HA, Goodrich JA, Dervan PB, Gottesfeld JM. Promoter scanning for transcription inhibition with DNA-binding polyamides. Molecular and Cellular Biology. 22: 1723-33. PMID 11865052 DOI: 10.1128/Mcb.22.6.1723-1733.2002  0.845
2002 Luger K, Suto RK, Edayathumangalam R, Gottesfeld J, Melander C, Dervan PB. Structural basis for site-specific recognition of nucleosomal DNA Acta Crystallographica Section a Foundations of Crystallography. 58: c35-c35. DOI: 10.1107/S0108767302086506  0.759
2002 Marques MA, Doss RM, Urbach AR, Dervan PB. Toward an understanding of the chemical etiology for DNA minor-groove recognition by polyamides Helvetica Chimica Acta. 85: 4485-4517. DOI: 10.1002/Hlca.200290024  0.849
2001 Dervan PB. Molecular recognition of DNA by small molecules. Bioorganic & Medicinal Chemistry. 9: 2215-35. PMID 11553460 DOI: 10.1016/S0968-0896(01)00262-0  0.315
2001 Wang CC, Dervan PB. Sequence-specific trapping of topoisomerase I by DNA binding polyamide-camptothecin conjugates. Journal of the American Chemical Society. 123: 8657-61. PMID 11535069 DOI: 10.1021/Ja010392P  0.679
2001 Bremer RE, Wurtz NR, Szewczyk JW, Dervan PB. Inhibition of major groove DNA binding bZIP proteins by positive patch polyamides. Bioorganic & Medicinal Chemistry. 9: 2093-103. PMID 11504645 DOI: 10.1016/S0968-0896(01)00122-5  0.868
2001 Trauger JW, Dervan PB. Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes. Methods in Enzymology. 340: 450-66. PMID 11494863 DOI: 10.1016/S0076-6879(01)40436-8  0.506
2001 Ansari AZ, Mapp AK, Nguyen DH, Dervan PB, Ptashne M. Towards a minimal motif for artificial transcriptional activators. Chemistry & Biology. 8: 583-92. PMID 11410377 DOI: 10.1016/S1074-5521(01)00037-0  0.771
2001 Gottesfeld JM, Melander C, Suto RK, Raviol H, Luger K, Dervan PB. Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. Journal of Molecular Biology. 309: 615-29. PMID 11397084 DOI: 10.1006/Jmbi.2001.4694  0.834
2001 Wurtz NR, Turner JM, Baird EE, Dervan PB. Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids. Organic Letters. 3: 1201-3. PMID 11348194 DOI: 10.1021/Ol0156796  0.817
2001 Wang CC, Ellervik U, Dervan PB. Expanding the recognition of the minor groove of DNA by incorporation of beta-alanine in hairpin polyamides. Bioorganic & Medicinal Chemistry. 9: 653-7. PMID 11310600 DOI: 10.1016/S0968-0896(00)00282-0  0.538
2001 Urbach AR, Dervan PB. Toward rules for 1:1 polyamide:DNA recognition. Proceedings of the National Academy of Sciences of the United States of America. 98: 4343-8. PMID 11296283 DOI: 10.1073/Pnas.081070798  0.694
2001 Nguyen DH, Szewczyk JW, Baird EE, Dervan PB. Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for A.T/T.A base pairs. Bioorganic & Medicinal Chemistry. 9: 7-17. PMID 11197348 DOI: 10.1016/S0968-0896(00)00219-4  0.723
2001 Baliga R, Baird EE, Herman DM, Melander C, Dervan PB, Crothers DM. Kinetic consequences of covalent linkage of DNA binding polyamides. Biochemistry. 40: 3-8. PMID 11141050 DOI: 10.1021/Bi0022339  0.677
2000 Melander C, Herman DM, Dervan PB. Discrimination of A/T sequences in the minor groove of DNA within a cyclic polyamide motif. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 4487-97. PMID 11192081 DOI: 10.1002/1521-3765(20001215)6:24<4487::Aid-Chem4487>3.0.Co;2-C  0.674
2000 Gottesfeld JM, Turner JM, Dervan PB. Chemical approaches to control gene expression. Gene Expression. 9: 77-91. PMID 11097426 DOI: 10.3727/000000001783992696  0.773
2000 Zhan ZY, Dervan PB. Alternative heterocycles for DNA recognition: a 3-pyrazole/pyrrole pair specifies for G.C base pairs. Bioorganic & Medicinal Chemistry. 8: 2467-74. PMID 11058042 DOI: 10.1016/S0968-0896(00)00182-6  0.538
2000 Bremer RE, Szewczyk JW, Baird EE, Dervan PB. Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole. Bioorganic & Medicinal Chemistry. 8: 1947-55. PMID 11003140 DOI: 10.1016/S0968-0896(00)00145-0  0.821
2000 Winston RL, Ehley JA, Baird EE, Dervan PB, Gottesfeld JM. Asymmetric DNA binding by a homodimeric bHLH protein. Biochemistry. 39: 9092-8. PMID 10924102 DOI: 10.1021/Bi000947D  0.807
2000 Chiang SY, Burli RW, Benz CC, Gawron L, Scott GK, Dervan PB, Beerman TA. Targeting the ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides. The Journal of Biological Chemistry. 275: 24246-54. PMID 10818092 DOI: 10.1074/Jbc.M000820200  0.511
2000 Simon H, Kittler L, Baird E, Dervan P, Zimmer C. Selective inhibition of DNA gyrase in vitro by a GC specific eight-ring hairpin polyamide at nanomolar concentration Febs Letters. 471: 173-176. PMID 10767417 DOI: 10.1016/S0014-5793(00)01390-9  0.505
2000 Mapp AK, Ansari AZ, Ptashne M, Dervan PB. Activation of gene expression by small molecule transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 97: 3930-5. PMID 10760265 DOI: 10.1073/Pnas.97.8.3930  0.741
2000 Wurtz NR, Dervan PB. Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates. Chemistry & Biology. 7: 153-61. PMID 10712931 DOI: 10.1016/S1074-5521(00)00085-5  0.836
2000 Kielkopf CL, Bremer RE, White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB, Rees DC. Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove. Journal of Molecular Biology. 295: 557-67. PMID 10623546 DOI: 10.1006/Jmbi.1999.3364  0.841
2000 Chang AY, Dervan PB. Strand selective cleavage of DNA by diastereomers of hairpin polyamide- seco-CBI conjugates Journal of the American Chemical Society. 122: 4856-4864. DOI: 10.1021/Ja994345X  0.697
2000 Ellervik U, Wang CCC, Dervan PB. Hydroxybenzamide/pyrrole pair distinguishes T·A from A·T base pairs in the minor groove of DNA Journal of the American Chemical Society. 122: 9354-9360. DOI: 10.1021/Ja001692U  0.476
2000 Floreancig PE, Swalley SE, Trauger JW, Dervan PB. Recognition of the minor groove of DNA by hairpin polyamides containing α-substituted-β-amino acids Journal of the American Chemical Society. 122: 6342-6350. DOI: 10.1021/Ja000509U  0.629
2000 Hawkins CA, Peláez De Clairac R, Dominey RN, Baird EE, White S, Dervan PB, Wemmer DE. Controlling binding orientation in hairpin polyamide DNA complexes Journal of the American Chemical Society. 122: X. DOI: 10.1021/Ja0001198  0.464
2000 Hawkins CA, Peláez De Clairac R, Dominey RN, Baird EE, White S, Dervan PB, Wemmer DE. Controlling binding orientation in hairpin polyamide DNA complexes Journal of the American Chemical Society. 122: X. DOI: 10.1021/ja0001198  0.397
2000 Mapp AK, Dervan PB. Preparation of thioesters for the ligation of peptides with non-native substrates Tetrahedron Letters. 41: 9451-9454. DOI: 10.1016/S0040-4039(00)01600-2  0.585
2000 Minehan TG, Gottwald K, Dervan PB. ChemInform Abstract: Molecular Recognition of DNA by Hoechst Benzimidazoles: Exploring Beyond the Pyrrole-Imidazole-Hydroxypyrrole Polyamide-Pairing Code. Cheminform. 31: no-no. DOI: 10.1002/chin.200048143  0.328
2000 Minehan TG, Gottwald K, Dervan PB. Molecular recognition of DNA by Hoechst benzimidazoles: Exploring beyond the pyrrole-imidazole-hydroxypyrrole polyamide-pairing code Helvetica Chimica Acta. 83: 2197-2213. DOI: 10.1002/1522-2675(20000906)83:9<2197::Aid-Hlca2197>3.0.Co;2-N  0.473
1999 Dervan PB, Bürli RW. Sequence-specific DNA recognition by polyamides. Current Opinion in Chemical Biology. 3: 688-93. PMID 10600731 DOI: 10.1016/S1367-5931(99)00027-7  0.569
1999 Lenzmeier BA, Baird EE, Dervan PB, Nyborg JK. The tax protein-DNA interaction is essential for HTLV-I transactivation in vitro. Journal of Molecular Biology. 291: 731-44. PMID 10452885 DOI: 10.1006/Jmbi.1999.2969  0.503
1999 Dickinson LA, Trauger JW, Baird EE, Ghazal P, Dervan PB, Gottesfeld JM. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides. Biochemistry. 38: 10801-7. PMID 10451376 DOI: 10.1021/Bi9912847  0.797
1999 Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. The Journal of Biological Chemistry. 274: 12765-73. PMID 10212261 DOI: 10.1074/jbc.274.18.12765  0.775
1999 McBryant SJ, Baird EE, Trauger JW, Dervan PB, Gottesfeld JM. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand. Journal of Molecular Biology. 286: 973-81. PMID 10047474 DOI: 10.1006/Jmbi.1999.2539  0.809
1999 Pilch DS, Poklar N, Baird EE, Dervan PB, Breslauer KJ. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. Biochemistry. 38: 2143-51. PMID 10026298 DOI: 10.1021/Bi982628G  0.514
1999 Urbach AR, Szewczyk JW, White S, Turner JM, Baird EE, Dervan PB. Sequence selectivity of 3-hydroxypyrrole/pyrrole ring pairings in the DNA minor groove Journal of the American Chemical Society. 121: 11621-11629. DOI: 10.1021/Ja9930667  0.825
1999 De Clairac RPL, Seel CJ, Geierstanger BH, Mrksich M, Baird EE, Dervan PB, Wemmer DE. NMR characterization of the aliphatic β/β pairing for recognition of A·T/T·A base pairs in the minor groove of DNA Journal of the American Chemical Society. 121: 2956-2964. DOI: 10.1021/Ja983671U  0.586
1999 Herman DM, Turner JM, Baird EE, Dervan PB. Cycle polyamide motif for recognition of the minor groove of DNA Journal of the American Chemical Society. 121: 1121-1129. DOI: 10.1021/Ja983206X  0.71
1999 Swalley SE, Baird EE, Dervan PB. Effects of γ-Turn and β-Tail Amino Acids on Sequence-Specific Recognition of DNA by Hairpin Polyamides Journal of the American Chemical Society. 121: X-1119. DOI: 10.1021/Ja9830905  0.501
1999 White S, Turner JM, Szewczyk JW, Baird EE, Dervan PB. Affinity and specificity of multiple hydroxypyrrole/pyrrole ring pairings for coded recognition of DNA [8] Journal of the American Chemical Society. 121: 260-261. DOI: 10.1021/Ja9830593  0.683
1999 Herman DM, Baird EE, Dervan PB. Tandem hairpin motif for recognition in the minor groove of DNA by pyrrole - Imidazole polyamides Chemistry - a European Journal. 5: 975-983. DOI: 10.1002/(Sici)1521-3765(19990301)5:3<975::Aid-Chem975>3.0.Co;2-T  0.567
1998 Trauger JW, Baird EE, Dervan PB. Cooperative Hairpin Dimers for Recognition of DNA by Pyrrole-Imidazole Polyamides. Angewandte Chemie (International Ed. in English). 37: 1421-1423. PMID 29710894 DOI: 10.1002/(Sici)1521-3773(19980605)37:10<1421::Aid-Anie1421>3.0.Co;2-8  0.505
1998 Dickinson LA, Gulizia RJ, Trauger JW, Baird EE, Mosier DE, Gottesfeld JM, Dervan PB. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proceedings of the National Academy of Sciences of the United States of America. 95: 12890-5. PMID 9789010 DOI: 10.1073/Pnas.95.22.12890  0.803
1998 Kielkopf CL, White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB, Rees DC. A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA. Science (New York, N.Y.). 282: 111-5. PMID 9756473 DOI: 10.1126/Science.282.5386.111  0.617
1998 Bachelin M, Hessler G, Kurz G, Hacia JG, Dervan PB, Kessler H. Structure of a stereoregular phosphorothioate DNA/RNA duplex. Nature Structural Biology. 5: 271-6. PMID 9546216 DOI: 10.1038/Nsb0498-271  0.464
1998 Bremer RE, Baird EE, Dervan PB. Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch. Chemistry & Biology. 5: 119-33. PMID 9545429 DOI: 10.1016/S1074-5521(98)90057-6  0.835
1998 White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB. Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature. 391: 468-71. PMID 9461213 DOI: 10.1038/35106  0.678
1998 Kielkopf CL, Baird EE, Dervan PB, Rees DC. Structural basis for G.C recognition in the DNA minor groove. Nature Structural Biology. 5: 104-9. PMID 9461074 DOI: 10.1038/Nsb0298-104  0.558
1998 Turner JM, Swalley SE, Baird EE, Dervan PB. Aliphatic/aromatic amino acid pairings for polyamide recognition in the minor groove of DNA Journal of the American Chemical Society. 120: 6219-6226. DOI: 10.1021/Ja980147E  0.574
1998 Trauger JW, Baird EE, Dervan PB. Recognition of 16 Base Pairs in the Minor Groove of DNA by a Pyrrole−Imidazole Polyamide Dimer Journal of the American Chemical Society. 120: 3534-3535. DOI: 10.1021/Ja9800378  0.606
1998 Herman DM, Baird EE, Dervan PB. Stereochemical control of the DNA binding affinity, sequence specificity, and orientation preference of chiral hairpin polyamides in the minor groove Journal of the American Chemical Society. 120: 1382-1391. DOI: 10.1021/ja9737228  0.437
1998 Trauger JW, Baird EE, Dervan PB. Cooperative hairpin dimers for recognition of DNA by pyrrole-imidazole polyamides Angewandte Chemie - International Edition. 37: 1421-1423. DOI: 10.1002/(SICI)1521-3773(19980605)37:10<1421::AID-ANIE1421>3.0.CO;2-8  0.423
1998 Greenberg WA, Baird EE, Dervan PB. A comparison of H-pin and hairpin polyamide motifs for the recognition of the minor groove of DNA Chemistry - a European Journal. 4: 796-805. DOI: 10.1002/(Sici)1521-3765(19980515)4:5<796::Aid-Chem796>3.0.Co;2-G  0.503
1998 Trauger J, Baird E, Dervan P. Kooperative Haarnadel-Dimere für die Erkennung von DNA durch Pyrrol/Imidazol-Polyamide Angewandte Chemie. 110: 1489-1492. DOI: 10.1002/(Sici)1521-3757(19980518)110:10<1489::Aid-Ange1489>3.0.Co;2-W  0.411
1997 Neely L, Trauger JW, Baird EE, Dervan PB, Gottesfeld JM. Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex. Journal of Molecular Biology. 274: 439-45. PMID 9417925 DOI: 10.1006/Jmbi.1997.1411  0.819
1997 White S, Baird EE, Dervan PB. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides. Chemistry & Biology. 4: 569-78. PMID 9281524 DOI: 10.1016/S1074-5521(97)90243-X  0.497
1997 Wemmer DE, Dervan PB. Targeting the minor groove of DNA. Current Opinion in Structural Biology. 7: 355-61. PMID 9204277 DOI: 10.1016/S0959-440X(97)80051-6  0.541
1997 Taylor MJ, Dervan PB. Kinetic analysis of sequence-specific alkylation of DNA by pyrimidine oligodeoxyribonucleotide-directed triple-helix formation. Bioconjugate Chemistry. 8: 354-64. PMID 9177841 DOI: 10.1021/Bc970035X  0.464
1997 Gottesfeld JM, Neely L, Trauger JW, Baird EE, Dervan PB. Regulation of gene expression by small molecules. Nature. 387: 202-5. PMID 9144294 DOI: 10.1038/387202A0  0.814
1997 Koshlap KM, Schultze P, Brunar H, Dervan PB, Feigon J. Solution structure of an intramolecular DNA triplex containing an N7- glycosylated guanine which mimics a protonated cytosine Biochemistry. 36: 2659-2668. PMID 9054573 DOI: 10.1021/Bi962438A  0.342
1997 White S, Baird EE, Dervan PB. Orientation preferences of pyrrole-imidazole polyamides in the minor groove of DNA Journal of the American Chemical Society. 119: 8756-8765. DOI: 10.1021/Ja971569B  0.468
1997 Turner JM, Baird EE, Dervan PB. Recognition of seven base pair sequences in the minor groove of DNA by ten-ring pyrrole-imidazole polyamide hairpins Journal of the American Chemical Society. 119: 7636-7644. DOI: 10.1021/Ja971208W  0.702
1997 Swalley SE, Baird EE, Dervan PB. Discrimination of 5'-GGGG-3', 5'-GCGC-3', and 5'-GGCC-3' sequences in the minor groove of DNA by eight-ring hairpin polyamides Journal of the American Chemical Society. 119: 6953-6961. DOI: 10.1021/Ja971184T  0.49
1997 Lamamie De Clairac RP, Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. NMR characterization of hairpin polyamide complexes with the minor groove of DNA Journal of the American Chemical Society. 119: 7909-7916. DOI: 10.1021/Ja964314R  0.645
1997 Lehmann TE, Greenberg WA, Liberies DA, Wada CK, Dervan PB. Triple-helix formation by pyrimidine oligonucleotide containing nonnatural nucleosides with extended aromatic nucleobases: Intercalation from the major groove as a method for recognizing C·G and T·A base pairs Helvetica Chimica Acta. 80: 2002-2022. DOI: 10.1002/Hlca.19970800618  0.361
1997 Swalley SE, Baird EE, Dervan PB. A pyrrole-imidazole polyamide motif for recognition of eleven base pair sequences in the minor groove of DNA Chemistry - a European Journal. 3: 1600-1607. DOI: 10.1002/Chem.19970031009  0.448
1996 Parks ME, Dervan PB. Simultaneous binding of a polyamide dimer and an oligonucleotide in the minor and major grooves of DNA. Bioorganic & Medicinal Chemistry. 4: 1045-50. PMID 8831975 DOI: 10.1016/0968-0896(96)00089-2  0.519
1996 White S, Baird EE, Dervan PB. Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA. Biochemistry. 35: 12532-7. PMID 8823190 DOI: 10.1021/Bi960744I  0.366
1996 Grant KB, Dervan PB. Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation. Biochemistry. 35: 12313-9. PMID 8823165 DOI: 10.1021/Bi9608469  0.794
1996 Trauger JW, Baird EE, Dervan PB. Extended hairpin polyamide motif for sequence-specific recognition in the minor groove of DNA. Chemistry & Biology. 3: 369-77. PMID 8807866 DOI: 10.1016/S1074-5521(96)90120-9  0.503
1996 Liberles DA, Dervan PB. Design of artificial sequence-specific DNA bending ligands. Proceedings of the National Academy of Sciences of the United States of America. 93: 9510-4. PMID 8790361 DOI: 10.1073/Pnas.93.18.9510  0.733
1996 Pilch DS, Poklar N, Gelfand CA, Law SM, Breslauer KJ, Baird EE, Dervan PB. Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination. Proceedings of the National Academy of Sciences of the United States of America. 93: 8306-11. PMID 8710866 DOI: 10.1073/Pnas.93.16.8306  0.508
1996 Trauger JW, Baird EE, Dervan PB. Recognition of DNA by designed ligands at subnanomolar concentrations. Nature. 382: 559-61. PMID 8700233 DOI: 10.1038/382559A0  0.535
1996 Kelly JJ, Baird EE, Dervan PB. Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif. Proceedings of the National Academy of Sciences of the United States of America. 93: 6981-5. PMID 8692930 DOI: 10.1073/Pnas.93.14.6981  0.567
1996 Brunar H, Dervan PB. Sequence composition effects on the stabilities of triple helix formation by oligonucleotides containing N7-deoxyguanosine. Nucleic Acids Research. 24: 1987-91. PMID 8668526 DOI: 10.1093/Nar/24.11.1987  0.313
1996 Wang E, Koshlap KM, Gillespie P, Dervan PB, Feigon J. Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. Journal of Molecular Biology. 257: 1052-69. PMID 8632468 DOI: 10.1006/Jmbi.1996.0223  0.421
1996 Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. Extending the recognition site of designed minor groove binding molecules. Nature Structural Biology. 3: 321-4. PMID 8599756 DOI: 10.1038/Nsb0496-321  0.616
1996 Swalley SE, Baird EE, Dervan PB. Recognition of a 5'-(A,T)GGG(A,T)2-3' sequence in the minor groove of DNA by an eight-ring hairpin polyamide Journal of the American Chemical Society. 118: 8198-8206. DOI: 10.1021/Ja9611598  0.482
1996 Szewczyk JW, Baird EE, Dervan PB. Cooperative triple-helix formation via a minor groove dimerization domain Journal of the American Chemical Society. 118: 6778-6779. DOI: 10.1021/Ja960831Y  0.553
1996 Parks ME, Baird EE, Dervan PB. Recognition of 5'-(A,T)GG(A,T)2-3' sequences in the minor groove of DNA by hairpin polyamides Journal of the American Chemical Society. 118: 6153-6159. DOI: 10.1021/Ja9607289  0.432
1996 Trauger JW, Baird EE, Mrksich M, Dervan PB. Extension of sequence-specific recognition in the minor groove of DNA by pyrrole-imidazole polyamides to 9-13 base pairs Journal of the American Chemical Society. 118: 6160-6166. DOI: 10.1021/Ja960726O  0.665
1996 Parks ME, Baird EE, Dervan PB. Optimization of the hairpin polyamide design for recognition of the minor groove of DNA Journal of the American Chemical Society. 118: 6147-6152. DOI: 10.1021/Ja960721R  0.535
1996 Baird EE, Dervan PB. Solid phase synthesis of polyamides containing imidazole and pyrrole amino acids Journal of the American Chemical Society. 118: 6141-6146. DOI: 10.1021/Ja960720Z  0.441
1996 Szewczyk JW, Baird EE, Dervan PB. Sequence-specific recognition of DNA by a major and minor groove binding ligand Angewandte Chemie (International Edition in English). 35: 1487-1489. DOI: 10.1002/Anie.199614871  0.556
1996 Szewczyk JW, Baird EE, Dervan PB. Sequenzspezifische DNA-Erkennung durch einen in der großen und der kleinen Furche bindenden Liganden Angewandte Chemie. 108: 1596-1598. DOI: 10.1002/Ange.19961081312  0.491
1995 Chen L, Oakley MG, Glover JN, Jain J, Dervan PB, Hogan PG, Rao A, Verdine GL. Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Current Biology : Cb. 5: 882-9. PMID 7583146 DOI: 10.1016/S0960-9822(95)00178-3  0.477
1995 Baliga R, Singleton JW, Dervan PB. RecA.oligonucleotide filaments bind in the minor groove of double-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 10393-7. PMID 7479791 DOI: 10.1073/Pnas.92.22.10393  0.524
1995 Cho J, Parks ME, Dervan PB. Cyclic polyamides for recognition in the minor groove of DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 10389-92. PMID 7479790 DOI: 10.1073/Pnas.92.22.10389  0.553
1995 Colocci N, Dervan PB. Cooperative triple-helix formation at adjacent DNA sites: Sequence composition dependence at the junction Journal of the American Chemical Society. 117: 4781-4787. DOI: 10.1021/Ja00122A007  0.473
1995 Priestley ES, Dervan PB. Sequence composition effects on the energetics of triple helix formation by oligonucleotides containing a designed mimic of protonated cytosine Journal of the American Chemical Society. 117: 4761-4765. DOI: 10.1021/Ja00122A004  0.304
1995 Mrksich M, Dervan PB. Recognition in the minor groove of DNA at 5′-(A,T)GCGC(A,T)-3′ by a four ring tripeptide dimer. Reversal of the specificity of the natural product distamycin Journal of the American Chemical Society. 117: 3325-3332. DOI: 10.1021/Ja00117A002  0.658
1995 Hunziker J, Priestley ES, Brunar H, Dervan PB. Design of an N7-glycosylated purine nucleoside for recognition of GC base pairs by triple helix formation Journal of the American Chemical Society. 117: 2661-2662. DOI: 10.1021/Ja00114A036  0.432
1995 Greenberg WA, Dervan PB. Energetics of formation of sixteen triple helical complexes which vary at a single position within a purine motif Journal of the American Chemical Society. 117: 5016-5019. DOI: 10.1021/Ja00109A001  0.322
1994 Hacia JG, Dervan PB, Wold BJ. Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation. Biochemistry. 33: 6192-200. PMID 8193133 DOI: 10.1021/Bi00186A019  0.516
1994 Hacia JG, Wold BJ, Dervan PB. Phosphorothioate oligonucleotide-directed triple helix formation. Biochemistry. 33: 5367-9. PMID 8180158 DOI: 10.1021/Bi00184A002  0.54
1994 Geierstanger BH, Jacobsen JP, Mrksich M, Dervan PB, Wemmer DE. Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA. Biochemistry. 33: 3055-62. PMID 8130219 DOI: 10.1021/Bi00176A039  0.633
1994 Han H, Schepartz A, Pellegrini M, Dervan PB. Mapping RNA regions in eukaryotic ribosomes that are accessible to methidiumpropyl-EDTA.Fe(II) and EDTA.Fe(II). Biochemistry. 33: 9831-44. PMID 8060991 DOI: 10.1021/Bi00199A004  0.464
1994 Staubli AB, Dervan PB. Sequence specificity of the non-natural pyrido[2,3-d]pyrimidine nucleoside in triple helix formation. Nucleic Acids Research. 22: 2637-42. PMID 8041626 DOI: 10.1093/Nar/22.13.2637  0.405
1994 Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. Design of a G.C-specific DNA minor groove-binding peptide. Science (New York, N.Y.). 266: 646-50. PMID 7939719 DOI: 10.1126/Science.7939719  0.674
1994 Oakley MG, Turnbull KD, Dervan PB. Synthesis of a hybrid protein containing the iron-binding ligand of bleomycin and the DNA-binding domain of Hin. Bioconjugate Chemistry. 5: 242-7. PMID 7522582 DOI: 10.1021/Bc00027A009  0.514
1994 Han H, Dervan PB. Different conformational families of pyrimidine.purine.pyrimidine triple helices depending on backbone composition. Nucleic Acids Research. 22: 2837-44. PMID 7519770 DOI: 10.1093/Nar/22.14.2837  0.401
1994 Singleton SF, Dervan PB. Temperature dependence of the energetics of oligonucleotide-directed triple-helix formation at a single DNA site Journal of the American Chemical Society. 116: 10376-10382. DOI: 10.1021/Ja00102A003  0.387
1994 Khundkar LR, Perry JW, Hanson JE, Dervan PB. Weak Temperature Dependence of Electron Transfer Rates in Fixed-Distance Porphyrin-Quinone Model Systems Journal of the American Chemical Society. 116: 9700-9709. DOI: 10.1021/Ja00100A040  0.675
1994 Mrksich M, Parks ME, Dervan PB. Hairpin peptide motif. A new class of oligopeptides for sequence-specific recognition in the minor groove of double-helical DNA Journal of the American Chemical Society. 116: 7983-7988. DOI: 10.1021/Ja00097A004  0.647
1994 Mrksich M, Dervan PB. Design of a Covalent Peptide Heterodimer for Sequence-Specific Recognition in the Minor Groove of Double-Helical DNA Journal of the American Chemical Society. 116: 3663-3664. DOI: 10.1021/Ja00087A088  0.647
1994 Colocci N, Dervan PB. Cooperative Binding of 8-mer Oligonucleotides Containing 5-(1-Propynyl)-2'-deoxyuridine to Adjacent DNA Sites by Triple-Helix Formation Journal of the American Chemical Society. 116: 785-786. DOI: 10.1021/Ja00081A056  0.512
1993 Iverson BL, Dervan PB. Adenine-specific DNA chemical sequencing reaction. Methods in Enzymology. 218: 222-7. PMID 8510534 DOI: 10.1016/0076-6879(93)18017-7  0.664
1993 MacDonald ME, Ambrose CM, Duyao MP, Myers RH, Lin C, Srinidhi L, Barnes G, Taylor SA, James M, Groot N, MacFarlane H, Jenkins B, Anderson MA, Wexler NS, Gusella JF, ... ... Dervan P, et al. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell. 72: 971-983. PMID 8458085 DOI: 10.1016/0092-8674(93)90585-E  0.563
1993 Stilz HU, Dervan PB. Specific recognition of CG base pairs by 2-deoxynebularine within the purine.purine.pyrimidine triple-helix motif. Biochemistry. 32: 2177-85. PMID 8443159 DOI: 10.1021/Bi00060A008  0.448
1993 Distefano MD, Dervan PB. Energetics of cooperative binding of oligonucleotides with discrete dimerization domains to DNA by triple helix formation. Proceedings of the National Academy of Sciences of the United States of America. 90: 1179-83. PMID 8433980 DOI: 10.1073/Pnas.90.4.1179  0.711
1993 Feng JA, Simon M, Mack DP, Dervan PB, Johnson RC, Dickerson RE. Crystallization and preliminary X-ray analysis of the DNA binding domain of the Hin recombinase with its DNA binding site. Journal of Molecular Biology. 232: 982-6. PMID 8355281 DOI: 10.1006/Jmbi.1993.1443  0.514
1993 Singleton SF, Dervan PB. Equilibrium association constants for oligonucleotide-directed triple helix formation at single DNA sites: linkage to cation valence and concentration. Biochemistry. 32: 13171-9. PMID 8241171 DOI: 10.1021/Bi00211A028  0.328
1993 Wade WS, Mrksich M, Dervan PB. Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA. Biochemistry. 32: 11385-9. PMID 8218203 DOI: 10.1021/Bi00093A015  0.643
1993 Radhakrishnan I, Patel DJ, Priestly ES, Nash HM, Dervan PB. NMR structural studies on a nonnatural deoxyribonucleoside which mediates recognition of GC base pairs in pyrimidine-purine-pyrimidine DNA triplexes. Biochemistry. 32: 11228-34. PMID 8218188 DOI: 10.1021/Bi00092A037  0.437
1993 Han H, Dervan PB. Sequence-specific recognition of double helical RNA and RNA.DNA by triple helix formation. Proceedings of the National Academy of Sciences of the United States of America. 90: 3806-10. PMID 7683407 DOI: 10.1073/Pnas.90.9.3806  0.439
1993 Dwyer TJ, Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. Structural analysis of covalent peptide dimers, bis(pyridine-2-carboxamidonetropsin)(CH_2)_(3-6), in complex with 5'-TGACT-3' sites by two-dimensional NMR Journal of the American Chemical Society. 115: 9900-9906. DOI: 10.1021/Ja00075A005  0.609
1993 Mrksich M, Dervan PB. Enhanced sequence specific recognition in the minor groove of DNA by covalent peptide dimers: bis(pyridine-2-carboxamidonetropsin)(CH2)3-6 Journal of the American Chemical Society. 115: 9892-9899. DOI: 10.1021/Ja00075A004  0.632
1993 Koshlap KM, Gillespie P, Dervan PB, Feigon J. Nonnatural deoxyribonucleoside D3 incorporated in an intramolecular DNA triplex binds sequence-specifically by intercalation Journal of the American Chemical Society. 115: 7908-7909. DOI: 10.1021/Ja00070A059  0.541
1993 Colocci N, Distefano MD, Dervan PB. Cooperative oligonucleotide-directed triple helix formation at adjacent DNA sites Journal of the American Chemical Society. 115: 4468-4473. DOI: 10.1021/Ja00064A008  0.633
1993 Tor Y, Dervan PB. Site-specific enzymic incorporation of an unnatural base, N6-(6-aminohexyl)isoguanosine, into RNA Journal of the American Chemical Society. 115: 4461-4467. DOI: 10.1021/Ja00064A007  0.549
1993 Mrksich M, Dervan PB. Antiparallel side-by-side heterodimer for sequence-specific recognition in the minor groove of DNA by a distamycin/1-methylimidazole-2-carboxamide-netropsin pair Journal of the American Chemical Society. 115: 2572-2576. DOI: 10.1021/Ja00060A004  0.655
1993 Baliga R, VanDevanter DR, Dervan PB. Characterization of myc amplicon size and orientation by triple helix mediated single site enzymatic cleavage Cancer Genetics and Cytogenetics. 66: 155. DOI: 10.1016/0165-4608(93)90305-6  0.301
1992 Maher LJ, Dervan PB, Wold B. Analysis of promoter-specific repression by triple-helical DNA complexes in a eukaryotic cell-free transcription system. Biochemistry. 31: 70-81. PMID 1731886 DOI: 10.1021/Bi00116A012  0.478
1992 Luebke KJ, Dervan PB. Nonenymatic ligation of double-helical DNA by alternate-strand triple helix formation. Nucleic Acids Research. 20: 3005-9. PMID 1620596 DOI: 10.1093/Nar/20.12.3005  0.5
1992 Beal PA, Dervan PB. The influence of single base triplet changes on the stability of a pur.pur.pyr triple helix determined by affinity cleaving. Nucleic Acids Research. 20: 2773-6. PMID 1614865 DOI: 10.1093/Nar/20.11.2773  0.625
1992 Kiessling LL, Griffin LC, Dervan PB. Flanking sequence effects within the pyrimidine triple-helix motif characterized by affinity cleaving. Biochemistry. 31: 2829-34. PMID 1547224 DOI: 10.1021/Bi00125A026  0.541
1992 Dervan PB. Reagents for the site-specific cleavage of megabase DNA. Nature. 359: 87-8. PMID 1522894 DOI: 10.1038/359087A0  0.513
1992 Singleton SF, Dervan PB. Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites. Biochemistry. 31: 10995-1003. PMID 1445837 DOI: 10.1021/Bi00160A008  0.362
1992 Oakley MG, Mrksich M, Dervan PB. Evidence that a minor groove-binding peptide and a major groove-binding protein can simultaneously occupy a common site on DNA. Biochemistry. 31: 10969-75. PMID 1445835 DOI: 10.1021/Bi00160A005  0.687
1992 Mack DP, Dervan PB. Sequence-specific oxidative cleavage of DNA by a designed metalloprotein, Ni(II).GGH(Hin139-190). Biochemistry. 31: 9399-405. PMID 1390723 DOI: 10.1021/Bi00154A011  0.479
1992 Strobel SA, Dervan PB. Triple helix-mediated single-site enzymatic cleavage of megabase genomic DNA. Methods in Enzymology. 216: 309-21. PMID 1336095 DOI: 10.1016/0076-6879(92)16029-J  0.679
1992 Mrksich M, Wade WS, Dwyer TJ, Geierstanger BH, Wemmer DE, Dervan PB. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proceedings of the National Academy of Sciences of the United States of America. 89: 7586-90. PMID 1323845 DOI: 10.1073/Pnas.89.16.7586  0.69
1992 Distefano MD, Dervan PB. Ligand-promoted dimerization of oligonucleotides binding cooperatively to DNA Journal of the American Chemical Society. 114: 11006-11007. DOI: 10.1021/Ja00053A073  0.704
1992 Wade WS, Mrksich M, Dervan PB. Design of peptides that bind in the minor groove of DNA at 5'-(A,T)G(A,T)C(A,T)-3' sequences by a dimeric side-by-side motif Journal of the American Chemical Society. 114: 8783-8794. DOI: 10.1021/Ja00049A006  0.644
1992 Griffin LC, Kiessling LL, Beal PA, Gillespie P, Dervan PB. Recognition of all four base pairs of double-helical DNA by triple-helix formation: design of nonnatural deoxyribonucleosides for pyrimidine.cntdot.purine base pair binding Journal of the American Chemical Society. 114: 7976-7982. DOI: 10.1021/Ja00047A003  0.76
1992 Singleton SF, Dervan PB. Thermodynamics of oligodeoxyribonucleotide-directed triple helix formation: an analysis using quantitative affinity cleavage titration Journal of the American Chemical Society. 114: 6957-6965. DOI: 10.1021/Ja00044A002  0.477
1992 Povsic TJ, Strobel SA, Dervan PB. Sequence-specific double-strand alkylation and cleavage of DNA mediated by triple-helix formation Journal of the American Chemical Society. 114: 5934-5941. DOI: 10.1021/Ja00041A005  0.711
1992 Beal PA, Dervan PB. Recognition of double helical DNA by alternate strand triple helix formation Journal of the American Chemical Society. 114: 4976-4982. DOI: 10.1021/Ja00039A004  0.725
1992 Koh JS, Dervan PB. Design of a nonnatural deoxyribonucleoside for recognition of GC base pairs by oligonucleotide-directed triple helix formation Journal of the American Chemical Society. 114: 1470-1478. DOI: 10.1021/Ja00030A050  0.383
1991 Beal PA, Dervan PB. Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation. Science (New York, N.Y.). 251: 1360-3. PMID 2003222 DOI: 10.1126/Science.2003222  0.743
1991 Shin JA, Ebright RH, Dervan PB. Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving. Nucleic Acids Research. 19: 5233-6. PMID 1923807 DOI: 10.1093/Nar/19.19.5233  0.554
1991 Horne DA, Dervan PB. Effects of an abasic site on triple helix formation characterized by affinity cleaving. Nucleic Acids Research. 19: 4963-5. PMID 1923764 DOI: 10.1093/Nar/19.18.4963  0.619
1991 Strobel SA, Dervan PB. Single-site enzymatic cleavage of yeast genomic DNA mediated by triple helix formation. Nature. 350: 172-4. PMID 1848684 DOI: 10.1038/350172A0  0.7
1991 Strobel SA, Doucette-Stamm LA, Riba L, Housman DE, Dervan PB. Site-specific cleavage of human chromosome 4 mediated by triple-helix formation. Science (New York, N.Y.). 254: 1639-42. PMID 1836279 DOI: 10.1126/Science.1836279  0.602
1991 Maher LJ, Wold B, Dervan PB. Oligonucleotide-directed DNA triple-helix formation: an approach to artificial repressors? Antisense Research and Development. 1: 277-81. PMID 1821648 DOI: 10.1089/Ard.1991.1.277  0.559
1991 Dervan PB. Characterization of protein-DNA complexes by affinity cleaving. Methods in Enzymology. 208: 497-515. PMID 1779845 DOI: 10.1016/0076-6879(91)08026-E  0.53
1991 Luebke KJ, Dervan PB. Nonenzymic sequence-specific ligation of double-helical DNA Journal of the American Chemical Society. 113: 7447-7448. DOI: 10.1021/Ja00019A066  0.509
1991 Distefano MD, Shin JA, Dervan PB. Cooperative binding of oligonucleotides to DNA by triple helix formation: dimerization via Watson-Crick hydrogen bonds Journal of the American Chemical Society. 113: 5901-5902. DOI: 10.1021/Ja00015A076  0.7
1990 Häner R, Dervan PB. Single-strand DNA triple-helix formation. Biochemistry. 29: 9761-5. PMID 2271614 DOI: 10.1021/Bi00494A001  0.456
1990 Maher LJ, Dervan PB, Wold BJ. Kinetic analysis of oligodeoxyribonucleotide-directed triple-helix formation on DNA. Biochemistry. 29: 8820-6. PMID 2271558 DOI: 10.1021/Bi00489A045  0.463
1990 Plum GE, Park YW, Singleton SF, Dervan PB, Breslauer KJ. Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study. Proceedings of the National Academy of Sciences of the United States of America. 87: 9436-40. PMID 2251285 DOI: 10.1073/Pnas.87.23.9436  0.381
1990 Mack DP, Sluka JP, Shin JA, Griffin JH, Simon MI, Dervan PB. Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the hix site. Biochemistry. 29: 6561-7. PMID 2204416 DOI: 10.1021/Bi00480A003  0.675
1990 Sluka JP, Horvath SJ, Glasgow AC, Simon MI, Dervan PB. Importance of minor-groove contacts for recognition of DNA by the binding domain of Hin recombinase. Biochemistry. 29: 6551-61. PMID 2204415 DOI: 10.1021/Bi00480A002  0.562
1990 Strobel SA, Dervan PB. Site-specific cleavage of a yeast chromosome by oligonucleotide-directed triple-helix formation. Science (New York, N.Y.). 249: 73-5. PMID 2195655 DOI: 10.1126/Science.2195655  0.682
1990 Graham KS, Dervan PB. Structural motif of the DNA binding domain of gamma delta-resolvase characterized by affinity cleaving. The Journal of Biological Chemistry. 265: 16534-40. PMID 2168893  0.468
1990 Oakley MG, Dervan PB. Structural motif of the GCN4 DNA binding domain characterized by affinity cleaving. Science (New York, N.Y.). 248: 847-50. PMID 2111578 DOI: 10.1126/Science.2111578  0.534
1990 Povsic TJ, Dervan PB. Sequence-specific alkylation of double-helical DNA by oligonucleotide-directed triple-helix formation Journal of the American Chemical Society. 112: 9428-9430. DOI: 10.1021/Ja00181A075  0.593
1990 Sluka JP, Griffin JH, Mack DP, Dervan PB. Reagents and methods for the solid-phase synthesis of protein-EDTA for use in affinity cleaving Journal of the American Chemical Society. 112: 6369-6374. DOI: 10.1021/Ja00173A027  0.483
1990 Mack DP, Dervan PB. Nickel-mediated sequence-specific oxidative cleavage of DNA by a designed metalloprotein Journal of the American Chemical Society. 112: 4604-4606. DOI: 10.1021/Ja00167A102  0.555
1990 Horne DA, Dervan PB. Recognition of mixed-sequence duplex DNA by alternate-strand triple-helix formation Journal of the American Chemical Society. 112: 2435-2437. DOI: 10.1021/Ja00162A063  0.565
1989 Wang AH, Cottens S, Dervan PB, Yesinowski JP, van der Marel GA, van Boom JH. Interactions between a symmetrical minor groove binding compound and DNA oligonucleotides: 1H and 19F NMR studies. Journal of Biomolecular Structure & Dynamics. 7: 101-17. PMID 2818866 DOI: 10.1080/07391102.1989.10507754  0.444
1989 Martello PA, Bruzik JP, deHaseth P, Youngquist RS, Dervan PB. Specific activation of open complex formation at an Escherichia coli promoter by oligo(N-methylpyrrolecarboxamide)s: effects of peptide length and identification of DNA target sites. Biochemistry. 28: 4455-61. PMID 2669956 DOI: 10.1021/Bi00436A050  0.492
1989 Griffin LC, Dervan PB. Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif. Science (New York, N.Y.). 245: 967-71. PMID 2549639 DOI: 10.1126/Science.2549639  0.565
1989 Maher LJ, Wold B, Dervan PB. Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation. Science (New York, N.Y.). 245: 725-30. PMID 2549631 DOI: 10.1126/Science.2549631  0.572
1989 Luebke KJ, Dervan PB. Nonenzymatic ligation of oligodeoxyribonucleotides on a duplex DNA template by triple-helix formation Journal of the American Chemical Society. 111: 8733-8735. DOI: 10.1021/Ja00205A033  0.527
1989 Strobel SA, Dervan PB. Cooperative site specific binding of oligonucleotides to duplex DNA Journal of the American Chemical Society. 111: 7286-7287. DOI: 10.1021/Ja00200A073  0.721
1989 Povsic TJ, Dervan PB. Triple helix formation by oligonucleotides on DNA extended to the physiological pH range Journal of the American Chemical Society. 111: 3059-3061. DOI: 10.1021/Ja00190A047  0.491
1989 Baker BF, Dervan PB. Sequence-specific cleavage of DNA by N-bromoacetyldistamycin. Product and kinetic analyses Journal of the American Chemical Society. 111: 2700-2712. DOI: 10.1021/Ja00189A054  0.519
1989 Dervan P. Design of sequence specific DNA-cleaving metalloproteins Journal of Inorganic Biochemistry. 36: 272. DOI: 10.1016/0162-0134(89)84370-3  0.373
1989 MACK DP, IVERSON BL, DERVAN PB. ChemInform Abstract: Design and Chemical Synthesis of a Sequence-Specific DNA-Cleaving Protein. Cheminform. 20. DOI: 10.1002/chin.198907282  0.628
1988 Iverson BL, Dervan PB. Nonenzymatic sequence-specific methyl transfer to single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 4615-9. PMID 3387429 DOI: 10.1073/Pnas.85.13.4615  0.701
1988 Strobel SA, Moser HE, Dervan PB. Double strand cleavage of genomic DNA at a single site by triple helix formation Journal of the American Chemical Society. 110: 7927-7929. DOI: 10.1021/Ja00231A082  0.689
1988 Mack DP, Iverson BL, Dervan PB. Design and chemical synthesis of a sequence-specific DNA-cleaving protein Journal of the American Chemical Society. 110: 7572-7574. DOI: 10.1021/Ja00230A067  0.707
1988 YOUNGQUIST RS, DERVAN PB. ChemInform Abstract: A Synthetic Peptide Binds 16 Base Pairs of A,T Double Helical DNA. Cheminform. 19. DOI: 10.1002/chin.198812314  0.366
1988 GRIFFIN JH, DERVAN PB. ChemInform Abstract: Metalloregulation in the Sequence Specific Binding of Synthetic Molecules to DNA. Cheminform. 19. DOI: 10.1002/chin.198808340  0.618
1987 Iverson BL, Dervan PB. Adenine specific DNA chemical sequencing reaction. Nucleic Acids Research. 15: 7823-30. PMID 3671067 DOI: 10.1093/Nar/15.19.7823  0.634
1987 Sluka JP, Horvath SJ, Bruist MF, Simon MI, Dervan PB. Synthesis of a sequence-specific DNA-cleaving peptide. Science (New York, N.Y.). 238: 1129-32. PMID 3120311 DOI: 10.1126/Science.3120311  0.508
1987 Moser HE, Dervan PB. Sequence-specific cleavage of double helical DNA by triple helix formation. Science (New York, N.Y.). 238: 645-50. PMID 3118463 DOI: 10.1126/Science.3118463  0.544
1987 Mendel D, Dervan PB. Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA. Proceedings of the National Academy of Sciences of the United States of America. 84: 910-4. PMID 3103127 DOI: 10.1073/Pnas.84.4.910  0.85
1987 Youngquist RS, Dervan PB. A synthetic peptide binds 16 base pairs of A,T double helical DNA Journal of the American Chemical Society. 109: 7564-7566. DOI: 10.1021/Ja00258A070  0.574
1987 Griffin JH, Dervan PB. Metalloregulation in the sequence specific binding of synthetic molecules to DNA Journal of the American Chemical Society. 109: 6840-6842. DOI: 10.1021/Ja00256A043  0.652
1987 Wade WS, Dervan PB. Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide Journal of the American Chemical Society. 109: 1574-1575. DOI: 10.1021/Ja00239A050  0.495
1987 Iverson BL, Dervan PB. Nonenzymatic sequence-specific cleavage of single-stranded DNA to nucleotide resolution. DNA methyl thioether probes Journal of the American Chemical Society. 109: 1241-1243. DOI: 10.1021/Ja00238A041  0.701
1987 WADE WS, DERVAN PB. ChemInform Abstract: Alteration of the Sequence Specificity of Distamycin on DNA by Replacement of an N-Methylpyrrolecarboxamide with Pyridine-2-carboxamide. Cheminform. 18. DOI: 10.1002/chin.198729328  0.391
1987 IVERSON BL, DERVAN PB. ChemInform Abstract: Nonenzymatic Sequence-Specific Cleavage of Single-Stranded DNA to Nucleotide Resolution. DNA Methyl Thioether Probes. Cheminform. 18. DOI: 10.1002/chin.198726315  0.665
1986 Dervan PB, Baker BF. Design of sequence-specific DNA cleaving molecules. Comparison of distamycin-EDTA X Fe(II) and N-bromoacetyldistamycin. Annals of the New York Academy of Sciences. 471: 51-9. PMID 3089122 DOI: 10.1111/J.1749-6632.1986.Tb48025.X  0.576
1986 Dervan PB. Design of sequence-specific DNA-binding molecules. Science (New York, N.Y.). 232: 464-71. PMID 2421408 DOI: 10.1126/Science.2421408  0.561
1986 Griffin JH, Dervan PB. Specific sequence-specific recognition of right-handed double-helical DNA by (2S,3S)- and (2R,3R)-dihydroxybis(netropsin)succinamide Journal of the American Chemical Society. 108: 5008-5009. DOI: 10.1021/Ja00276A052  0.558
1986 GRIFFIN JH, DERVAN PB. ChemInform Abstract: Sequence-Specific Chiral Recognition of Right-Handed Double-Helical DNA by (2S,3S)- (Ia) and (2R,3R)-Dihydroxybis(netropsin)succinamide (Ib). Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198650085  0.45
1986 BAKER BF, DERVAN PB. ChemInform Abstract: Sequence-Specific Cleavage of Double-Helical DNA. N-Bromoacetyldistamycin. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198616349  0.397
1985 Dreyer GB, Dervan PB. Sequence-specific cleavage of single-stranded DNA: oligodeoxynucleotide-EDTA X Fe(II). Proceedings of the National Academy of Sciences of the United States of America. 82: 968-72. PMID 3919391 DOI: 10.1073/Pnas.82.4.968  0.462
1985 Berger CL, Cantor C, Welsh J, Dervan P, Begley T, Grant S, Gasparro FP, Edelson RL. Comparison of synthetic psoralen derivatives and 8-MOP in the inhibition of lymphocyte proliferation. Annals of the New York Academy of Sciences. 453: 80-90. PMID 3865599 DOI: 10.1111/J.1749-6632.1985.Tb11800.X  0.614
1985 Youngquist RS, Dervan PB. Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s. Proceedings of the National Academy of Sciences of the United States of America. 82: 2565-9. PMID 2986122 DOI: 10.1073/Pnas.82.9.2565  0.523
1985 Harshman KD, Dervan PB. Molecular recognition of B-DNA by Hoechst 33258. Nucleic Acids Research. 13: 4825-35. PMID 2410856 DOI: 10.1093/Nar/13.13.4825  0.482
1985 Baker BF, Dervan PB. Sequence-specific cleavage of double-helical DNA. N-Bromoacetyldistamycin Journal of the American Chemical Society. 107: 8266-8268. DOI: 10.1021/Ja00312A079  0.463
1985 YOUNGQUIST RS, DERVAN PB. ChemInform Abstract: SEQUENCE-SPECIFIC RECOGNITION OF B DNA BY BIS(EDTA-DISTAMYCIN)FUMARAMIDE Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198552327  0.363
1985 Youngquist RS, Dervan PB. Sequence-specific recognition of B DNA by bis(EDTA-distamycin)fumaramide Journal of the American Chemical Society. 107: 5528-5529. DOI: 10.1002/Chin.198552327  0.472
1984 Hertzberg RP, Dervan PB. Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses. Biochemistry. 23: 3934-45. PMID 6435669 DOI: 10.1021/Bi00312A022  0.441
1984 Schultz PG, Dervan PB. Distamycin and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving. Journal of Biomolecular Structure & Dynamics. 1: 1133-47. PMID 6101078 DOI: 10.1080/07391102.1984.10507508  0.699
1984 Van Dyke MM, Dervan PB. Echinomycin binding sites on DNA Science. 225: 1122-1127. PMID 6089341 DOI: 10.1126/Science.6089341  0.559
1984 Sylwester AP, Dervan PB. Low-temperature matrix isolation of the 1,1-diazene H2NN. Electronic and infrared characterization Journal of the American Chemical Society. 106: 4648-4650. DOI: 10.1021/Ja00328A076  0.758
1984 Taylor JS, Schultz PG, Dervan PB. DNA affinity cleaving Tetrahedron. 40: 457-465. DOI: 10.1016/0040-4020(84)85050-4  0.667
1984 SCHULTZ PG, DERVAN PB. ChemInform Abstract: SEQUENCE-SPECIFIC DOUBLE-STRAND CLEAVAGE OF DNA BY BIS(EDTA-DISTAMYCIN.IRON(II)) AND EDTA-BIS(DISTAMYCIN).IRON(II) Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198414295  0.552
1983 Schultz PG, Dervan PB. Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II). Proceedings of the National Academy of Sciences of the United States of America. 80: 6834-7. PMID 6417654 DOI: 10.1073/Pnas.80.22.6834  0.645
1983 Cartwright IL, Hertzberg RP, Dervan PB, Elgin SC. Cleavage of chromatin with methidiumpropyl-EDTA . iron(II). Proceedings of the National Academy of Sciences of the United States of America. 80: 3213-7. PMID 6407008 DOI: 10.1073/Pnas.80.11.3213  0.404
1983 Van Dyke MW, Dervan PB. Footprinting with MPE.Fe(II). Complementary-strand analyses of distamycin- and actinomycin-binding sites on heterogeneous DNA Cold Spring Harbor Symposia On Quantitative Biology. 47: 347-353. PMID 6305557 DOI: 10.1101/Sqb.1983.047.01.040  0.348
1983 Van Dyke MW, Dervan PB. Methidiumpropyl-EDTA.Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA. Nucleic Acids Research. 11: 5555-67. PMID 6225070 DOI: 10.1093/Nar/11.16.5555  0.472
1983 Van Dyke MW, Dervan PB. Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous deoxyribonucleic acid. Footprinting with (methidiumpropyl-EDTA)iron( II ) Biochemistry. 22: 2373-2377. PMID 6222762 DOI: 10.1021/Bi00279A011  0.506
1983 Schultz PG, Dervan PB. Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin.iron(II)) and EDTA-bis(distamycin).iron(II) Journal of the American Chemical Society. 105: 7748-7750. DOI: 10.1021/ja00364a049  0.551
1983 SCHULTZ PG, TAYLOR JS, DERVAN PB. ChemInform Abstract: DESIGN SYNTHESIS OF A SEQUENCE-SPECIFIC DNA CLEAVING MOLECULE. (DISTAMYCIN-EDTA)IRON(II) Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198310308  0.595
1983 SCHULTZ PG, DERVAN PB. ChemInform Abstract: PHOTOCHEMISTRY OF 1,1-DIAZENES. DIRECT AND SENSITIZED PHOTOLYSES OF N-(2,2,5,5-TETRAMETHYLPYRROLIDYL)NITRENE, DL-N-(2,5-DIETHYL-2,5-DIMETHYLPYRROLIDYL)NITRENE, AND N-(2,2,6,6-TETRAMETHYLPIPERIDYL)NITRENE Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198309115  0.463
1982 Van Dyke MW, Hertzberg RP, Dervan PB. Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II). Proceedings of the National Academy of Sciences of the United States of America. 79: 5470-4. PMID 6291045 DOI: 10.1073/Pnas.79.18.5470  0.5
1982 Shultz PG, Taylor JS, Dervan PB. Design synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II) Journal of the American Chemical Society. 104: 6861-6863. DOI: 10.1021/Ja00388A101  0.531
1982 Schultz PG, Dervan PB. Photochemistry of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene, dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene Journal of the American Chemical Society. 104: 6660-6668. DOI: 10.1021/Ja00388A031  0.516
1982 Mitchell MA, Dervan PB. Interhelical DNA-DNA crosslinking. Bis(monoazidomethidium)octaoxahexacosanediamine: a probe of packaged nucleic acid Journal of the American Chemical Society. 104: 4265-4266. DOI: 10.1021/Ja00379A045  0.485
1982 Hinsberg WD, Schultz PG, Dervan PB. Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene Journal of the American Chemical Society. 104: 766-773. DOI: 10.1021/Ja00367A020  0.518
1982 Hertzberg RP, Dervan PB. Cleavage of double helical DNA by methidium-propyl-EDTA-iron(II) Journal of the American Chemical Society. 104: 313-315. DOI: 10.1021/Ja00365A069  0.465
1982 Ikeda RA, Dervan PB. Sequence-selective inhibition of restriction endonucleases by the polyintercalator bis(methidium)spermine Journal of the American Chemical Society. 104: 296-297. DOI: 10.1021/Ja00365A058  0.488
1982 MITCHELL MA, DERVAN PB. ChemInform Abstract: INTERHELICAL DNA-DNA CROSSLINKING. BIS(MONOAZIDOMETHIDIUM)OCTAOXAHEXACOSANEDIAMINE: A PROBE OF PACKAGED NUCLEIC ACID Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198244335  0.395
1982 HINSBERG WDI, SCHULTZ PG, DERVAN PB. ChemInform Abstract: DIRECT STUDIES OF 1,1-DIAZENES. SYNTHESES, INFRARED AND ELECTRONIC SPECTRA, AND KINETICS OF THE THERMAL DECOMPOSITION OF N-(2,2,6,6-TETRAMETHYLPIPERIDYL)NITRENE AND N-(2,2,5,5-TETRAMETHYLPYRROLIDYL)NITRENE Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198221093  0.465
1981 Schultz PG, Dervan PB. Photochemistry of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene Journal of the American Chemical Society. 103: 1563-1564. DOI: 10.1021/Ja00396A048  0.513
1981 Dervan PB, Squillacote ME, Lahti PM, Sylwester AP, Roberts JD. Nitrogen-15 NMR spectrum of a 1,1-diazene. N-(2,2,6,6-tetramethylpiperidyl)nitrene Journal of the American Chemical Society. 103: 1120-1122. DOI: 10.1021/Ja00395A021  0.758
1981 SCHULTZ PG, DERVAN PB. ChemInform Abstract: PHOTOCHEMISTRY OF A 1,1-DIAZENE, N-(2,2,5,5-TETRAMETHYLPYRROLIDINYL)NITRENE Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198127109  0.464
1980 Schultz PG, Dervan PB. Synthesis and direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene. Comparison of five- and six-membered cyclic 1,1-dialkyldiazenes Journal of the American Chemical Society. 102: 878-880. DOI: 10.1021/Ja00522A090  0.535
1980 SCHULTZ PG, DERVAN PB. ChemInform Abstract: SYNTHESIS AND DIRECT SPECTROSCOPIC OBSERVATION OF N-(2,2,5,5-TETRAMETHYLPYRROLIDINYL)NITRENE. COMPARISON OF FIVE- AND SIX-MEMBERED CYCLIC 1,1-DIALKYLDIAZENES Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198017126  0.487
1979 Becker MM, Dervan PB. Molecular recognition of nucleic acid by small molecules. Binding affinity and structural specificity of bis(methidium)spermine Journal of the American Chemical Society. 101: 3664-3666. DOI: 10.1021/Ja00507A046  0.375
1978 Dervan PB, Becker MM. Molecular recognition of DNA by small molecules. Synthesis of bis(methidium)spermine, a DNA polyintercalating molecule Journal of the American Chemical Society. 100: 1968-1970. DOI: 10.1021/Ja00474A075  0.466
1978 DERVAN PB, BECKER MM. ChemInform Abstract: MOLECULAR RECOGNITION OF DNA BY SMALL MOLECULES. SYNTHESIS OF BIS(METHIDIUM)SPERMINE, A DNA POLYINTERCALATING MOLECULE Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197828187  0.363
1976 Berson JA, Dervan PB, Malherbe R, Jenkins JA. Formation and thermal rearrangements of some dimers of butadiene and piperylene. Tests of the validity of thermochemical-kinetic arguments for identification of common biradical intermediates Journal of the American Chemical Society. 98: 5937-5968. DOI: 10.1021/Ja00435A031  0.603
1973 Berson JA, Dervan PB. Mechanistic analysis of the four pathways in the 1,3-sigmatropic rearrangements of trans-1,2-trans, trans- and trans-1,2-cis,trans-dipropenylcyclobutane Journal of the American Chemical Society. 95: 269-270. DOI: 10.1021/Ja00782A062  0.595
1973 Berson JA, Dervan PB. Rearrangement of trans-1,2-divinylcyclobutane and the energy surface of the dimers of butadiene Journal of the American Chemical Society. 95: 267-269. DOI: 10.1021/Ja00782A061  0.584
1973 BERSON JA, DERVAN PB. ChemInform Abstract: MECHANISTISCHE ANALYSE DER VIER RK.-WEGE BEI 1,3-SIGMATROPEN UMLAGERUNGEN VON TRANS-1,2-TRANS,TRANS- UND TRANS-1,2-CIS,TRANS-DIPROPENYL-CYCLOBUTAN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197312124  0.584
1973 BERSON JA, DERVAN PB. ChemInform Abstract: UMLAGERUNG VON TRANS-1,2-DIVINYL-CYCLOBUTAN UND DIE ENERGIEFLAECHE DER DIMEREN VON BUTADIEN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197312123  0.591
1973 BERSON JA, DERVAN PB. ChemInform Abstract: STEREODISTALE COPE-UMLAGERUNG VON TRANS-1,2-DIALKENYL-CYCLOBUTANEN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197308127  0.586
1972 Berson JA, Dervan PB. Stereodistal Cope rearrangement of trans-1,2-dialkenylcyclobutanes Journal of the American Chemical Society. 94: 8949-8950. DOI: 10.1021/Ja00780A074  0.589
1972 Berson JA, Dervan PB, Jenkins JA. Stereospecific double rearrangement of trans-3,4-dimethyl-cis,trans-cycloocta-1,5-diene to cis-3,4-dimethyl-cis,cis-cycloocta-1,5-diene Journal of the American Chemical Society. 94: 7598-7599. DOI: 10.1021/Ja00776A065  0.581
1972 Berson JA, Dervan PB. Incremental substituent effects leading to steric blockade of the boat-like six-center Cope rearrangement of cis-1,2-dialkenylcyclobutanes Journal of the American Chemical Society. 94: 7597-7598. DOI: 10.1021/Ja00776A064  0.586
1972 BERSON JA, DERVAN PB, JENKINS JA. ChemInform Abstract: STEREOSPEZIFISCHE DOPPELUMLAGERUNG VON TRANS-3,4-DIMETHYL-CIS,TRANS-CYCLOOCTADIEN-(1,5) ZU CIS-3,4-DIMETHYL-CIS,CIS-CYCLOOCTADIEN-(1,5) Chemischer Informationsdienst. 3. DOI: 10.1002/Chin.197252135  0.574
1972 BERSON JA, DERVAN PB. ChemInform Abstract: INKREMENTE DER SUBSTITUENTENEFFEKTE, DIE ZUR STERISCHEN BLOCKIERUNG DER BOOT-AEHNLICHEN 6-ZENTREN-COPE-UMLAGERUNG VON CIS-1,2-DIALKENYL-CYCLOBUTANEN FUEHREN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197252134  0.578
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