Robert Darnell - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Molecular Biology, Neuroscience Biology

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Year Citation  Score
2024 Saito Y, Yang Y, Saito M, Park CY, Funato K, Tabar V, Darnell RB. NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314695121. PMID 38416679 DOI: 10.1073/pnas.2314695121  0.412
2023 Irmady K, Hale CR, Qadri R, Fak J, Simelane S, Carroll T, Przedborski S, Darnell RB. Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease. Nature Communications. 14: 3956. PMID 37407548 DOI: 10.1038/s41467-023-39652-6  0.741
2023 Ibrahim LA, Wamsley B, Alghamdi N, Yusuf N, Sevier E, Hairston A, Sherer M, Jaglin XH, Xu Q, Guo L, Jamayran AK, Favuzzi E, Yuan Y, Dimidschstein J, Darnell RB, et al. Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing. Elife. 12. PMID 37347149 DOI: 10.7554/eLife.86842  0.328
2023 Tajima Y, Ito K, Yuan Y, Frank MO, Saito Y, Darnell RB. NOVA1 acts on Impact to regulate hypothalamic function and translation in inhibitory neurons. Cell Reports. 42: 112050. PMID 36716149 DOI: 10.1016/j.celrep.2023.112050  0.594
2022 Saito Y, Hawley BR, Puno MR, Sarathy SN, Lima CD, Jaffrey SR, Darnell RB, Keeney S, Jain D. YTHDC2 control of gametogenesis requires helicase activity but not mA binding. Genes & Development. 36: 180-194. PMID 35058317 DOI: 10.1101/gad.349190.121  0.341
2022 Darnell RB. Corrigendum: CLIP (Cross-Linking and Immunoprecipitation) Identification of RNAs Bound by a Specific Protein. Cold Spring Harbor Protocols. 2022: pdb.corr107811. PMID 34983862 DOI: 10.1101/pdb.corr107811  0.327
2021 Hale CR, Sawicka K, Mora K, Fak JJ, Kang JJ, Cutrim P, Cialowicz K, Carroll TS, Darnell RB. FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons. Elife. 10. PMID 34939924 DOI: 10.7554/eLife.71892  0.329
2021 Knupp D, Cooper DA, Saito Y, Darnell RB, Miura P. NOVA2 regulates neural circRNA biogenesis. Nucleic Acids Research. PMID 34157123 DOI: 10.1093/nar/gkab523  0.464
2021 Park CY, Zhou J, Wong AK, Chen KM, Theesfeld CL, Darnell RB, Troyanskaya OG. Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk. Nature Genetics. PMID 33462483 DOI: 10.1038/s41588-020-00761-3  0.337
2019 Sawicka K, Hale CR, Park CY, Fak JJ, Gresack JE, Van Driesche SJ, Kang JJ, Darnell JC, Darnell RB. FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory. Elife. 8. PMID 31860442 DOI: 10.7554/eLife.46919  0.355
2018 Saito Y, Yuan Y, Zucker-Scharff I, Fak JJ, Jereb S, Tajima Y, Licatalosi DD, Darnell RB. Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. Neuron. PMID 30638744 DOI: 10.1016/j.neuron.2018.12.019  0.811
2018 Darnell JC, Mele A, Hung KYS, Darnell RB. Mapping of In Vivo RNA-Binding Sites by Ultraviolet (UV)-Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.top097931. PMID 30510132 DOI: 10.1101/pdb.top097931  0.364
2018 Darnell JC, Mele A, Hung KYS, Darnell RB. 3'-Linker Ligation and Size Selection by SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.prot097964. PMID 30510127 DOI: 10.1101/pdb.prot097964  0.3
2018 Yuan Y, Xie S, Darnell JC, Darnell AJ, Saito Y, Phatnani H, Murphy EA, Zhang C, Maniatis T, Darnell RB. Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons. Genome Biology. 19: 117. PMID 30111345 DOI: 10.1186/S13059-018-1493-2  0.368
2018 Ule J, Hwang HW, Darnell RB. The Future of Cross-Linking and Immunoprecipitation (CLIP). Cold Spring Harbor Perspectives in Biology. 10. PMID 30068528 DOI: 10.1101/Cshperspect.A032243  0.638
2018 Moore MJ, Blachere NE, Fak JJ, Park CY, Sawicka K, Parveen S, Zucker-Scharff I, Moltedo B, Rudensky AY, Darnell RB. ZFP36 RNA-binding proteins restrain T-cell activation and anti-viral immunity. Elife. 7. PMID 29848443 DOI: 10.7554/Elife.33057  0.778
2018 Jereb S, Hwang HW, Van Otterloo E, Govek EE, Fak JJ, Yuan Y, Hatten ME, Darnell RB. Differential 3' processing of specific transcripts expands regulatory and protein diversity across neuronal cell types. Elife. 7. PMID 29578408 DOI: 10.7554/Elife.34042  0.365
2018 Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ. Elavl3 is essential for the maintenance of Purkinje neuron axons. Scientific Reports. 8: 2722. PMID 29426875 DOI: 10.1038/S41598-018-21130-5  0.336
2017 Blachère NE, Orange DE, Gantman EC, Santomasso BD, Couture GC, Ramirez-Montagut T, Fak J, O'Donovan KJ, Ru Z, Parveen S, Frank MO, Moore MJ, Darnell RB. T cells presenting viral antigens or autoantigens induce cytotoxic T cell anergy. Jci Insight. 2. PMID 29093272 DOI: 10.1172/jci.insight.96173  0.662
2017 Hwang HW, Saito Y, Park CY, Blachère NE, Tajima Y, Fak JJ, Zucker-Scharff I, Darnell RB. cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation. Neuron. 95: 1334-1349.e5. PMID 28910620 DOI: 10.1016/J.Neuron.2017.08.024  0.788
2017 Korb E, Herre M, Zucker-Scharff I, Gresack J, Allis CD, Darnell RB. Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell. PMID 28823556 DOI: 10.1016/J.Cell.2017.07.033  0.769
2016 Leggere JC, Saito Y, Darnell RB, Tessier-Lavigne M, Junge HJ, Chen Z. NOVA regulate Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Elife. 5. PMID 27223328 DOI: 10.7554/Elife.14264  0.325
2016 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB. NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 5. PMID 27223325 DOI: 10.7554/Elife.14371  0.762
2016 Hwang HW, Park CY, Goodarzi H, Fak JJ, Mele A, Moore MJ, Saito Y, Darnell RB. PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. Cell Reports. PMID 27050522 DOI: 10.1016/J.Celrep.2016.03.023  0.315
2016 Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB. Erratum: Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nature Protocols. 11: 616. PMID 26914319 DOI: 10.1038/nprot0316-616c  0.327
2016 Scheckel C, Drapeau E, Frias MA, Park CY, Fak J, Zucker-Scharff I, Kou Y, Haroutunian V, Ma'ayan A, Buxbaum JD, Darnell RB. Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain. Elife. 5. PMID 26894958 DOI: 10.7554/Elife.10421  0.803
2016 Chen BR, Robine N, Wrzeszczynski K, Vacic V, Emde AK, Arora K, Shah M, Grabowska EA, Felice V, Dikoglu E, Reeves C, Frank M, Jobanputra V, Zody MC, Bloom T, ... Darnell R, et al. Abstract 4498: RNA-Seq in the NYGC GBM Clinical Outcomes Pilot Study Cancer Research. 76: 4498-4498. DOI: 10.1158/1538-7445.Am2016-4498  0.421
2015 Ke S, Alemu EA, Mertens C, Gantman EC, Fak JJ, Mele A, Haripal B, Zucker-Scharff I, Moore MJ, Park CY, Vågbø CB, Kuśnierczyk A, Klungland A, Darnell JE, Darnell RB. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes & Development. PMID 26404942 DOI: 10.1101/Gad.269415.115  0.75
2015 Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A. Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP. Proceedings of the National Academy of Sciences of the United States of America. 112: E5391-400. PMID 26374839 DOI: 10.1073/Pnas.1515737112  0.343
2015 Korb E, Herre M, Zucker-Scharff I, Darnell RB, Allis CD. BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice. Nature Neuroscience. 18: 1464-73. PMID 26301327 DOI: 10.1038/Nn.4095  0.779
2014 Weyn-Vanhentenryck SM, Mele A, Yan Q, Sun S, Farny N, Zhang Z, Xue C, Herre M, Silver PA, Zhang MQ, Krainer AR, Darnell RB, Zhang C. HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. Cell Reports. 6: 1139-52. PMID 24613350 DOI: 10.1016/J.Celrep.2014.02.005  0.384
2014 Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB. Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nature Protocols. 9: 263-93. PMID 24407355 DOI: 10.1038/Nprot.2014.012  0.365
2013 Darnell RB. RNA protein interaction in neurons. Annual Review of Neuroscience. 36: 243-70. PMID 23701460 DOI: 10.1146/annurev-neuro-062912-114322  0.414
2013 Zhang C, Lee KY, Swanson MS, Darnell RB. Prediction of clustered RNA-binding protein motif sites in the mammalian genome. Nucleic Acids Research. 41: 6793-807. PMID 23685613 DOI: 10.1093/Nar/Gkt421  0.316
2013 Eom T, Zhang C, Wang H, Lay K, Fak J, Noebels JL, Darnell RB. NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Elife. 2: e00178. PMID 23359859 DOI: 10.7554/Elife.00178  0.441
2012 Darnell R. CLIP (cross-linking and immunoprecipitation) identification of RNAs bound by a specific protein. Cold Spring Harbor Protocols. 2012: 1146-60. PMID 23118367 DOI: 10.1101/Pdb.Prot072132  0.485
2012 Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, Yoo J, Herre M, Okano H, Noebels JL, Darnell RB. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 75: 1067-80. PMID 22998874 DOI: 10.1016/J.Neuron.2012.07.009  0.667
2012 Charizanis K, Lee KY, Batra R, Goodwin M, Zhang C, Yuan Y, Shiue L, Cline M, Scotti MM, Xia G, Kumar A, Ashizawa T, Clark HB, Kimura T, Takahashi MP, ... ... Darnell RB, et al. Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Neuron. 75: 437-50. PMID 22884328 DOI: 10.1016/J.Neuron.2012.05.029  0.34
2012 Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB. Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes & Development. 26: 1626-42. PMID 22802532 DOI: 10.1101/Gad.191338.112  0.428
2011 Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, Licatalosi DD, Richter JD, Darnell RB. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell. 146: 247-61. PMID 21784246 DOI: 10.1016/J.Cell.2011.06.013  0.442
2011 Teplova M, Malinina L, Darnell JC, Song J, Lu M, Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB, Patel DJ. Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. Structure (London, England : 1993). 19: 930-44. PMID 21742260 DOI: 10.1016/J.Str.2011.05.002  0.424
2011 Zhang C, Darnell RB. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nature Biotechnology. 29: 607-14. PMID 21633356 DOI: 10.1038/Nbt.1873  0.373
2011 Kakumoto K, Miyazaki T, Watanabe M, Darnell R, Okano H, Okano H. The maintenance of Purkinje axons by an RNA-binding protein HuC in adult cerebellum Neuroscience Research. 71: e95-e96. DOI: 10.1016/J.Neures.2011.07.410  0.416
2010 Darnell RB. HITS-CLIP: panoramic views of protein-RNA regulation in living cells. Wiley Interdisciplinary Reviews. Rna. 1: 266-86. PMID 21935890 DOI: 10.1002/wrna.31  0.375
2010 Allen SE, Darnell RB, Lipscombe D. The neuronal splicing factor Nova controls alternative splicing in N-type and P-type CaV2 calcium channels. Channels (Austin, Tex.). 4: 483-9. PMID 21150296 DOI: 10.4161/chan.4.6.12868  0.392
2010 Yano M, Hayakawa-Yano Y, Mele A, Darnell RB. Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 66: 848-58. PMID 20620871 DOI: 10.1016/j.neuron.2010.05.007  0.382
2010 Zhang C, Frias MA, Mele A, Ruggiu M, Eom T, Marney CB, Wang H, Licatalosi DD, Fak JJ, Darnell RB. Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls. Science (New York, N.Y.). 329: 439-43. PMID 20558669 DOI: 10.1126/Science.1191150  0.383
2010 Racca C, Gardiol A, Eom T, Ule J, Triller A, Darnell RB. The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite. Frontiers in Neural Circuits. 4: 5. PMID 20407637 DOI: 10.3389/Neuro.04.005.2010  0.684
2010 O'Donovan KJ, Diedler J, Couture GC, Fak JJ, Darnell RB. The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells. Plos One. 5: e10045. PMID 20383333 DOI: 10.1371/Journal.Pone.0010045  0.682
2010 Licatalosi DD, Darnell RB. RNA processing and its regulation: global insights into biological networks. Nature Reviews. Genetics. 11: 75-87. PMID 20019688 DOI: 10.1038/nrg2673  0.361
2009 Zang JB, Nosyreva ED, Spencer CM, Volk LJ, Musunuru K, Zhong R, Stone EF, Yuva-Paylor LA, Huber KM, Paylor R, Darnell JC, Darnell RB. A mouse model of the human Fragile X syndrome I304N mutation. Plos Genetics. 5: e1000758. PMID 20011099 DOI: 10.1371/journal.pgen.1000758  0.331
2009 Darnell JC, Fraser CE, Mostovetsky O, Darnell RB. Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Human Molecular Genetics. 18: 3164-77. PMID 19487368 DOI: 10.1093/hmg/ddp255  0.339
2008 Jensen KB, Darnell RB. CLIP: crosslinking and immunoprecipitation of in vivo RNA targets of RNA-binding proteins. Methods in Molecular Biology (Clifton, N.J.). 488: 85-98. PMID 18982285 DOI: 10.1007/978-1-60327-475-3_6  0.372
2008 Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB. HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature. 456: 464-9. PMID 18978773 DOI: 10.1038/nature07488  0.659
2007 Ule J, Darnell RB. Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain. Advances in Experimental Medicine and Biology. 623: 148-60. PMID 18380345  0.688
2007 Jelen N, Ule J, Zivin M, Darnell RB. Evolution of Nova-dependent splicing regulation in the brain. Plos Genetics. 3: 1838-47. PMID 17937501 DOI: 10.1371/journal.pgen.0030173  0.612
2006 Darnell RB. Developing global insight into RNA regulation. Cold Spring Harbor Symposia On Quantitative Biology. 71: 321-7. PMID 17381312 DOI: 10.1101/sqb.2006.71.002  0.427
2006 Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, Gaasterland T, Blencowe BJ, Darnell RB. An RNA map predicting Nova-dependent splicing regulation. Nature. 444: 580-6. PMID 17065982 DOI: 10.1038/Nature05304  0.733
2006 Ule J, Darnell RB. RNA binding proteins and the regulation of neuronal synaptic plasticity. Current Opinion in Neurobiology. 16: 102-10. PMID 16418001 DOI: 10.1016/j.conb.2006.01.003  0.658
2006 Ule J, Darnell R. [S18]: RNA regulation and modular control of the neuronal synapse International Journal of Developmental Neuroscience. 24: 479-479. DOI: 10.1016/j.ijdevneu.2006.09.023  0.348
2005 Ule J, Jensen K, Mele A, Darnell RB. CLIP: a method for identifying protein-RNA interaction sites in living cells. Methods (San Diego, Calif.). 37: 376-86. PMID 16314267 DOI: 10.1016/j.ymeth.2005.07.018  0.638
2005 Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan YN, Jan LY. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell. 123: 105-18. PMID 16213216 DOI: 10.1016/J.Cell.2005.07.033  0.55
2005 Darnell JC, Mostovetsky O, Darnell RB. FMRP RNA targets: identification and validation. Genes, Brain, and Behavior. 4: 341-9. PMID 16098133 DOI: 10.1111/j.1601-183X.2005.00144.x  0.377
2005 Ule J, Ule A, Spencer J, Williams A, Hu JS, Cline M, Wang H, Clark T, Fraser C, Ruggiu M, Zeeberg BR, Kane D, Weinstein JN, Blume J, Darnell RB. Nova regulates brain-specific splicing to shape the synapse. Nature Genetics. 37: 844-52. PMID 16041372 DOI: 10.1038/Ng1610  0.67
2005 Dredge BK, Stefani G, Engelhard CC, Darnell RB. Nova autoregulation reveals dual functions in neuronal splicing. The Embo Journal. 24: 1608-20. PMID 15933722 DOI: 10.1038/Sj.Emboj.7600630  0.631
2005 Darnell JC, Fraser CE, Mostovetsky O, Stefani G, Jones TA, Eddy SR, Darnell RB. Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes. Genes & Development. 19: 903-18. PMID 15805463 DOI: 10.1101/Gad.1276805  0.623
2005 Relógio A, Ben-Dov C, Baum M, Ruggiu M, Gemund C, Benes V, Darnell RB, Valcárcel J. Alternative splicing microarrays reveal functional expression of neuron-specific regulators in Hodgkin lymphoma cells. The Journal of Biological Chemistry. 280: 4779-84. PMID 15546866 DOI: 10.1074/jbc.M411976200  0.338
2004 Stefani G, Fraser CE, Darnell JC, Darnell RB. Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells Journal of Neuroscience. 24: 7272-7276. PMID 15317853 DOI: 10.1523/Jneurosci.2306-04.2004  0.621
2004 Darnell JC, Warren ST, Darnell RB. The Fragile X Mental Retardation Protein, FMRP, Recognizes G-Quartets Mental Retardation and Developmental Disabilities Research Reviews. 10: 49-52. PMID 14994288 DOI: 10.1002/Mrdd.20008  0.383
2003 Ule J, Jensen KB, Ruggiu M, Mele A, Ule A, Darnell RB. CLIP identifies Nova-regulated RNA networks in the brain. Science (New York, N.Y.). 302: 1212-5. PMID 14615540 DOI: 10.1126/science.1090095  0.698
2003 Dredge BK, Darnell RB. Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer. Molecular and Cellular Biology. 23: 4687-700. PMID 12808107 DOI: 10.1128/MCB.23.13.4687-4700.2003  0.323
2003 Farina KL, Huttelmaier S, Musunuru K, Darnell R, Singer RH. Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. The Journal of Cell Biology. 160: 77-87. PMID 12507992 DOI: 10.1083/Jcb.200206003  0.339
2002 Ito M, Okano HJ, Darnell RB, Roeder RG. The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development Embo Journal. 21: 3464-3475. PMID 12093747 DOI: 10.1093/emboj/cdf348  0.49
2001 O'Donovan KJ, Darnell RB. Neuronal signaling through alternative splicing: some exons CaRRE. Science's Stke : Signal Transduction Knowledge Environment. 2001: pe2. PMID 11752670 DOI: 10.1126/Stke.2001.94.Pe2  0.695
2001 Darnell JC, Jensen KB, Jin P, Brown V, Warren ST, Darnell RB. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function Cell. 107: 489-499. PMID 11719189 DOI: 10.1016/S0092-8674(01)00566-9  0.362
2001 Musunuru K, Darnell RB. Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration. Annual Review of Neuroscience. 24: 239-62. PMID 11283311 DOI: 10.1146/ANNUREV.NEURO.24.1.239  0.331
2001 Dredge BK, Polydorides AD, Darnell RB. The splice of life: alternative splicing and neurological disease. Nature Reviews. Neuroscience. 2: 43-50. PMID 11253358 DOI: 10.1038/35049061  0.399
2000 Ito M, Yuan CX, Okano HJ, Darnell RB, Roeder RG. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Molecular Cell. 5: 683-93. PMID 10882104 DOI: 10.1016/S1097-2765(00)80247-6  0.426
2000 Polydorides AD, Okano HJ, Yang YY, Stefani G, Darnell RB. A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 97: 6350-5. PMID 10829067 DOI: 10.1073/Pnas.110128397  0.658
2000 Jensen KB, Musunuru K, Lewis HA, Burley SK, Darnell RB. The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain. Proceedings of the National Academy of Sciences of the United States of America. 97: 5740-5. PMID 10811881 DOI: 10.1073/Pnas.090553997  0.338
2000 Jensen KB, Dredge BK, Stefani G, Zhong R, Buckanovich RJ, Okano HJ, Yang YY, Darnell RB. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron. 25: 359-71. PMID 10719891 DOI: 10.1016/S0896-6273(00)80900-9  0.647
2000 Lewis HA, Musunuru K, Jensen KB, Edo C, Chen H, Darnell RB, Burley SK. Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome. Cell. 100: 323-32. PMID 10676814 DOI: 10.1016/S0092-8674(00)80668-6  0.342
1999 Akamatsu W, Okano HJ, Osumi N, Inoue T, Nakamura S, Sakakibara S, Miura M, Matsuo N, Darnell RB, Okano H. Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems. Proceedings of the National Academy of Sciences of the United States of America. 96: 9885-90. PMID 10449789 DOI: 10.1073/Pnas.96.17.9885  0.397
1999 Lewis HA, Chen H, Edo C, Buckanovich RJ, Yang YY, Musunuru K, Zhong R, Darnell RB, Burley SK. Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. Structure (London, England : 1993). 7: 191-203. PMID 10368286 DOI: 10.1016/S0969-2126(99)80025-2  0.315
1998 Yang YY, Yin GL, Darnell RB. The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 13254-9. PMID 9789075 DOI: 10.1073/pnas.95.22.13254  0.4
1997 Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proceedings of the National Academy of Sciences of the United States of America. 94: 7001-5. PMID 9192681 DOI: 10.1073/Pnas.94.13.7001  0.321
1997 Buckanovich RJ, Darnell RB. The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Molecular and Cellular Biology. 17: 3194-201. PMID 9154818 DOI: 10.1128/MCB.17.6.3194  0.409
1997 Okano HJ, Darnell RB. A Hierarchy of Hu RNA Binding Proteins in Developing and Adult Neurons The Journal of Neuroscience. 17: 3024-3037. DOI: 10.1523/JNEUROSCI.17-09-03024.1997  0.365
1996 Darnell RB. Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brain. Proceedings of the National Academy of Sciences of the United States of America. 93: 4529-36. PMID 8643438 DOI: 10.1073/pnas.93.10.4529  0.311
1996 Buckanovich R, Yang Y, Darnell R. The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies The Journal of Neuroscience. 16: 1114-1122. DOI: 10.1523/JNEUROSCI.16-03-01114.1996  0.349
1993 Buckanovich RJ, Posner JB, Darnell RB. Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system. Neuron. 11: 657-72. PMID 8398153 DOI: 10.1016/0896-6273(93)90077-5  0.372
1991 Darnell RB, Furneaux HM, Posner JB. Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1224-30. PMID 1851215 DOI: 10.1523/Jneurosci.11-05-01224.1991  0.324
Low-probability matches (unlikely to be authored by this person)
2016 Hwang JY, Lee J, Oh CK, Kang HW, Hwang IY, Um JW, Park HC, Kim S, Shin JH, Park WY, Darnell RB, Um HD, Chung KC, Kim K, Oh YJ. Proteolytic degradation and potential role of onconeural protein cdr2 in neurodegeneration. Cell Death & Disease. 7: e2240. PMID 27253404 DOI: 10.1038/Cddis.2016.151  0.295
1999 Okano HJ, Park WY, Corradi JP, Darnell RB. The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. Genes & Development. 13: 2087-97. PMID 10465786 DOI: 10.1101/gad.13.16.2087  0.293
2004 Darnell R. Tumor immunity in small-cell lung cancer Journal of Clinical Oncology. 22: 762-764. PMID 14990628 DOI: 10.1200/Jco.2004.12.936  0.29
2018 Darnell JC, Mele A, Hung KYS, Darnell RB. Immunoprecipitation and SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.prot097956. PMID 30510126 DOI: 10.1101/pdb.prot097956  0.285
2010 Darnell RB. RNA regulation in neurologic disease and cancer. Cancer Research and Treatment : Official Journal of Korean Cancer Association. 42: 125-9. PMID 20948916 DOI: 10.4143/crt.2010.42.3.125  0.284
2013 Poulos MG, Batra R, Li M, Yuan Y, Zhang C, Darnell RB, Swanson MS. Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Human Molecular Genetics. 22: 3547-58. PMID 23660517 DOI: 10.1093/Hmg/Ddt209  0.284
2019 Slotkin EK, Diolaiti D, Shukla NN, Dela Cruz FS, Clark JJ, Gundem G, Yellapantula VD, Levine MF, You D, Ma P, Pachhal S, Ibanez Sanchez G, Benayed R, Jungbluth AA, Smyth LM, ... ... Darnell R, et al. Patient-driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion-driven Cancer. Cancer Discovery. PMID 30877085 DOI: 10.1158/2159-8290.Cd-18-0953  0.281
2004 Ohba H, Chiyoda T, Endo E, Yano M, Hayakawa Y, Sakaguchi M, Darnell RB, Okano HJ, Okano H. Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1. Neuroscience Letters. 358: 157-60. PMID 15039105 DOI: 10.1016/J.Neulet.2004.01.026  0.275
2004 Musunuru K, Darnell RB. Determination and augmentation of RNA sequence specificity of the Nova K-homology domains Nucleic Acids Research. 32: 4852-4861. PMID 15367696 DOI: 10.1093/nar/gkh799  0.274
2009 Ruggiu M, Herbst R, Kim N, Jevsek M, Fak JJ, Mann MA, Fischbach G, Burden SJ, Darnell RB. Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing. Proceedings of the National Academy of Sciences of the United States of America. 106: 3513-8. PMID 19221030 DOI: 10.1073/Pnas.0813112106  0.272
2011 Phan AT, Kuryavyi V, Darnell JC, Serganov A, Majumdar A, Ilin S, Raslin T, Polonskaia A, Chen C, Clain D, Darnell RB, Patel DJ. Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nature Structural & Molecular Biology. 18: 796-804. PMID 21642970 DOI: 10.1038/Nsmb.2064  0.271
2019 Nachmani D, Bothmer AH, Grisendi S, Mele A, Bothmer D, Lee JD, Monteleone E, Cheng K, Zhang Y, Bester AC, Guzzetti A, Mitchell CA, Mendez LM, Pozdnyakova O, Sportoletti P, ... ... Darnell RB, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nature Genetics. PMID 31570891 DOI: 10.1038/S41588-019-0502-Z  0.268
2002 Darnell RB. RNA logic in time and space Cell. 110: 545-550. PMID 12230972 DOI: 10.1016/S0092-8674(02)00937-6  0.267
2017 Ke S, Pandya-Jones A, Saito Y, Fak JJ, Vågbø CB, Geula S, Hanna JH, Black DL, Darnell JE, Darnell RB. m(6)A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover. Genes & Development. 31: 990-1006. PMID 28637692 DOI: 10.1101/Gad.301036.117  0.267
2014 Vanharanta S, Marney CB, Shu W, Valiente M, Zou Y, Mele A, Darnell RB, Massagué J. Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. Elife. 3. PMID 24898756 DOI: 10.7554/Elife.02734  0.265
2001 Brown V, Jin P, Ceman S, Darnell JC, O'Donnell WT, Tenenbaum SA, Jin X, Feng Y, Wilkinson KD, Keene JD, Darnell RB, Warren ST. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell. 107: 477-87. PMID 11719188 DOI: 10.1016/S0092-8674(01)00568-2  0.265
2017 Hwang HW, Darnell RB. Comprehensive Identification of mRNA Polyadenylation Sites by PAPERCLIP. Methods in Molecular Biology (Clifton, N.J.). 1648: 79-93. PMID 28766291 DOI: 10.1007/978-1-4939-7204-3_7  0.257
2008 Roberts W, Deluca I, Thomas A, Buckley N, Darnell R. F.16. Identification of HuD-specific CD8+ T Cells in Paraneoplastic Neurologic Degeneration Patients with Tumor Immunity and Autoimmunity Clinical Immunology. 127: S48. DOI: 10.1016/J.Clim.2008.03.128  0.252
2009 DeLuca I, Blachère NE, Santomasso B, Darnell RB. Tolerance to the neuron-specific paraneoplastic HuD antigen. Plos One. 4: e5739. PMID 19492067 DOI: 10.1371/journal.pone.0005739  0.25
2017 Darnell RB, Ke S, Darnell JE. pre-mRNA processing includes N6 methylation of adenosine residues that are retained in mRNA exons and the fallacy of "RNA epigenetics". Rna (New York, N.Y.). PMID 29222117 DOI: 10.1261/Rna.065219.117  0.247
2006 Licatalosi DD, Darnell RB. Splicing regulation in neurologic disease. Neuron. 52: 93-101. PMID 17015229 DOI: 10.1016/j.neuron.2006.09.017  0.244
1982 Boime I, Boothby M, Hoshina M, Daniels-McQueen S, Darnell R. Expression and structures of human placental hormone genes as a function of placental development. Biology of Reproduction. 26: 73-91. PMID 6279188 DOI: 10.1095/Biolreprod26.1.73  0.244
2017 Freudenberg-Hua Y, Li W, Ben-Avraham D, Koppel J, Germer S, Darnell R, Barzilai N, Freudenberg J, Atzmon G, Davies P. [P3-118]: INCREASED BURDEN OF RARE LOSS-OF-FUNCTION VARIANTS IN ALZHEIMER's DISEASE PATIENTS COMPARED TO CENTENARIANS Alzheimer's & Dementia. 13: P980-P980. DOI: 10.1016/J.Jalz.2017.06.1329  0.237
1998 Fletcher CF, Okano HJ, Gilbert DJ, Yang Y, Yang C, Copeland NG, Jenkins NA, Darnell RB. Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. Genomics. 45: 313-9. PMID 9344654 DOI: 10.1006/Geno.1997.4925  0.236
2009 Chi SW, Zang JB, Mele A, Darnell RB. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature. 460: 479-86. PMID 19536157 DOI: 10.1038/nature08170  0.235
1991 Darnell R, Furneaux H, Posner J. Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors The Journal of Neuroscience. 11: 1224-1230. DOI: 10.1523/JNEUROSCI.11-05-01224.1991  0.234
2014 Blachère NE, Orange DE, Santomasso BD, Doerner J, Foo PK, Herre M, Fak J, Monette S, Gantman EC, Frank MO, Darnell RB. T cells targeting a neuronal paraneoplastic antigen mediate tumor rejection and trigger CNS autoimmunity with humoral activation. European Journal of Immunology. 44: 3240-51. PMID 25103845 DOI: 10.1002/eji.201444624  0.227
2018 Darnell JC, Mele A, Hung KYS, Darnell RB. Isolation of the RNA Cross-Linking Immunoprecipitation (CLIP) Tags, 5'-Linker Ligation, Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Amplification, and Sequencing. Cold Spring Harbor Protocols. 2018: pdb.prot097972. PMID 30510128 DOI: 10.1101/pdb.prot097972  0.216
2019 Kobayashi M, Benakis C, Anderson C, Moore MJ, Poon C, Uekawa K, Dyke JP, Fak JJ, Mele A, Park CY, Zhou P, Anrather J, Iadecola C, Darnell RB. AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke. Cell Reports. 28: 979-991.e6. PMID 31340158 DOI: 10.1016/J.Celrep.2019.06.075  0.212
2018 Darnell JC, Mele A, Hung KYS, Darnell RB. Ultraviolet (UV) Cross-Linking of Live Cells, Lysate Preparation, and RNase Titration for Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.prot097949. PMID 30510125 DOI: 10.1101/pdb.prot097949  0.202
2015 Cheung J, Ginter C, Cassidy M, Franklin MC, Rudolph MJ, Robine N, Darnell RB, Hendrickson WA. Structural insights into mis-regulation of protein kinase A in human tumors. Proceedings of the National Academy of Sciences of the United States of America. 112: 1374-9. PMID 25605907 DOI: 10.1073/Pnas.1424206112  0.201
2016 Scheel TK, Luna JM, Liniger M, Nishiuchi E, Rozen-Gagnon K, Shlomai A, Auray G, Gerber M, Fak J, Keller I, Bruggmann R, Darnell RB, Ruggli N, Rice CM. A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration. Cell Host & Microbe. 19: 409-423. PMID 26962949 DOI: 10.1016/J.Chom.2016.02.007  0.197
1993 Graus F, Rowe G, Fueyo J, Darnell RB, Dalmau J. The neuronal nuclear antigen recognized by the human anti-Ri autoantibody is expressed in central but not peripheral nervous system neurons. Neuroscience Letters. 150: 212-4. PMID 8469424 DOI: 10.1016/0304-3940(93)90538-V  0.195
2018 Stephenson W, Donlin LT, Butler A, Rozo C, Bracken B, Rashidfarrokhi A, Goodman SM, Ivashkiv LB, Bykerk VP, Orange DE, Darnell RB, Swerdlow HP, Satija R. Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation. Nature Communications. 9: 791. PMID 29476078 DOI: 10.1038/S41467-017-02659-X  0.193
1997 Corradi JP, Yang C, Darnell JC, Dalmau J, Darnell RB. A Post-Transcriptional Regulatory Mechanism Restricts Expression of the Paraneoplastic Cerebellar Degeneration Antigen cdr2 to Immune Privileged Tissues The Journal of Neuroscience. 17: 1406-1415. DOI: 10.1523/JNEUROSCI.17-04-01406.1997  0.193
2020 Orange DE, Yao V, Sawicka K, Fak J, Frank MO, Parveen S, Blachere NE, Hale C, Zhang F, Raychaudhuri S, Troyanskaya OG, Darnell RB. RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares. The New England Journal of Medicine. 383: 218-228. PMID 32668112 DOI: 10.1056/Nejmoa2004114  0.192
2020 Darnell RB. The Genetic Control of Stoichiometry Underlying Autism. Annual Review of Neuroscience. 43: 509-533. PMID 32640929 DOI: 10.1146/annurev-neuro-100119-024851  0.19
2017 Linderman JA, Kobayashi M, Rayannavar V, Fak JJ, Darnell RB, Chao MV, Wilson AC, Mohr I. Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen. Cell Reports. 18: 1312-1323. PMID 28147283 DOI: 10.1016/J.Celrep.2017.01.017  0.189
1998 Albert ML, Darnell JC, Bender A, Francisco LM, Bhardwaj N, Darnell RB. Tumor-specific killer cells in paraneoplastic cerebellar degeneration. Nature Medicine. 4: 1321-4. PMID 9809559 DOI: 10.1038/3315  0.187
2007 Santomasso BD, Roberts WK, Thomas A, Williams T, Blachère NE, Dudley ME, Houghton AN, Posner JB, Darnell RB. A T-cell receptor associated with naturally occurring human tumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 104: 19073-8. PMID 18045792 DOI: 10.1073/Pnas.0704336104  0.185
1998 Lim DS, Kirsch DG, Canman CE, Ahn JH, Ziv Y, Newman LS, Darnell RB, Shiloh Y, Kastan MB. ATM binds to beta-adaptin in cytoplasmic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 95: 10146-51. PMID 9707615 DOI: 10.1073/Pnas.95.17.10146  0.176
1999 Darnell RB. Immunologic complexity in neurons. Neuron. 21: 947-50. PMID 9856451 DOI: 10.1016/S0896-6273(00)80613-3  0.171
1984 Darnell RB. Independent regulation by sodium butyrate of gonadotropin alpha gene expression and cell cycle progression in HeLa cells. Molecular and Cellular Biology. 4: 829-39. PMID 6203027 DOI: 10.1128/MCB.4.5.829  0.171
2018 Diolaiti D, Dela Cruz FS, Gundem G, Bouvier N, Boulad M, Zhang Y, Chou AJ, Dunkel IJ, Sanghvi R, Shah M, Geiger H, Rahman S, Felice V, Wrzeszczynski KO, Darnell RB, et al. A recurrent novel MGA-NUTM1 fusion identifies a new subtype of high grade spindle cell sarcoma. Cold Spring Harbor Molecular Case Studies. PMID 30552129 DOI: 10.1101/mcs.a003194  0.168
2009 Roberts WK, Deluca IJ, Thomas A, Fak J, Williams T, Buckley N, Dousmanis AG, Posner JB, Darnell RB. Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells. The Journal of Clinical Investigation. 119: 2042-51. PMID 19509467 DOI: 10.1172/JCI36131  0.166
2004 Darnell RB. Paraneoplastic Neurologic Disorders: Windows into Neuronal Function and Tumor Immunity Archives of Neurology. 61: 30-32. PMID 14732616 DOI: 10.1001/archneur.61.1.30  0.166
2004 Roberts WK, Darnell RB. Neuroimmunology of the paraneoplastic neurological degenerations Current Opinion in Immunology. 16: 616-622. PMID 15342008 DOI: 10.1016/j.coi.2004.07.009  0.161
2016 Freudenberg-Hua Y, Li W, Abhyankar A, Vacic V, Cortes V, Ben-Avraham D, Koppel J, Greenwald B, Germer S, Darnell RB, Barzilai N, Freudenberg J, Atzmon G, Davies P. Differential Burden of Rare Protein Truncating Variants in Alzheimer's Disease Patients Compared to Centenarians. Human Molecular Genetics. PMID 27260402 DOI: 10.1093/Hmg/Ddw150  0.16
2015 Roberts WK, Blachère NE, Frank MO, Dousmanis A, Ransohoff RM, Darnell RB. A destructive feedback loop mediated by CXCL10 in central nervous system inflammatory disease. Annals of Neurology. 78: 619-29. PMID 26224283 DOI: 10.1002/ana.24494  0.16
2021 O'Connor S, Murphy EA, Szwed SK, Kanke M, Marchildon F, Sethupathy P, Darnell RB, Cohen P. AGO HITS-CLIP reveals distinct miRNA regulation of white and brown adipose tissue identity. Genes & Development. PMID 33832988 DOI: 10.1101/gad.345447.120  0.16
2012 Chi SW, Hannon GJ, Darnell RB. An alternative mode of microRNA target recognition. Nature Structural & Molecular Biology. 19: 321-7. PMID 22343717 DOI: 10.1038/Nsmb.2230  0.159
2019 Zhou J, Park CY, Theesfeld CL, Wong AK, Yuan Y, Scheckel C, Fak JJ, Funk J, Yao K, Tajima Y, Packer A, Darnell RB, Troyanskaya OG. Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nature Genetics. PMID 31133750 DOI: 10.1038/S41588-019-0420-0  0.158
2012 Iossifov I, Ronemus M, Levy D, Wang Z, Hakker I, Rosenbaum J, Yamrom B, Lee YH, Narzisi G, Leotta A, Kendall J, Grabowska E, Ma B, Marks S, Rodgers L, ... ... Darnell RB, et al. De novo gene disruptions in children on the autistic spectrum. Neuron. 74: 285-99. PMID 22542183 DOI: 10.1016/J.Neuron.2012.04.009  0.157
2013 Orange DE, Blachere NE, Fak J, Parveen S, Frank MO, Herre M, Tian S, Monette S, Darnell RB. Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo. Elife. 2: e00105. PMID 23390586 DOI: 10.7554/eLife.00105  0.156
1995 Newman LS, McKeever MO, Okano HJ, Darnell RB. β-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein Cell. 82: 773-783. PMID 7671305 DOI: 10.1016/0092-8674(95)90474-3  0.153
1993 Darnell RB, Victor J, Rubin M, Clouston P, Plum F. A novel antineuronal antibody in stiff-man syndrome. Neurology. 43: 114-20. PMID 8423873 DOI: 10.1212/WNL.43.1_Part_1.114  0.152
2017 Turner TN, Coe BP, Dickel DE, Hoekzema K, Nelson BJ, Zody MC, Kronenberg ZN, Hormozdiari F, Raja A, Pennacchio LA, Darnell RB, Eichler EE. Genomic Patterns of De Novo Mutation in Simplex Autism. Cell. PMID 28965761 DOI: 10.1016/J.Cell.2017.08.047  0.151
1996 Simpson F, Bright NA, West MA, Newman LS, Darnell RB, Robinson MS. A novel adaptor-related protein complex. The Journal of Cell Biology. 133: 749-60. PMID 8666661 DOI: 10.1083/jcb.133.4.749  0.15
2019 Kwart D, Gregg A, Scheckel C, Murphy EA, Paquet D, Duffield M, Fak J, Olsen O, Darnell RB, Tessier-Lavigne M. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ. Neuron. 104: 1022. PMID 31805257 DOI: 10.1016/j.neuron.2019.11.010  0.145
2015 Turner TN, Hormozdiari F, Duyzend MH, McClymont SA, Hook PW, Iossifov I, Raja A, Baker C, Hoekzema K, Stessman HA, Zody MC, Nelson BJ, Huddleston J, Sandstrom R, Smith JD, ... ... Darnell R, et al. Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA. American Journal of Human Genetics. PMID 26749308 DOI: 10.1016/J.Ajhg.2015.11.023  0.143
2019 Kwart D, Gregg A, Scheckel C, Murphy E, Paquet D, Duffield M, Fak J, Olsen O, Darnell R, Tessier-Lavigne M. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ. Neuron. PMID 31416668 DOI: 10.1016/J.Neuron.2019.07.010  0.141
2015 Moore MJ, Scheel TK, Luna JM, Park CY, Fak JJ, Nishiuchi E, Rice CM, Darnell RB. miRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity. Nature Communications. 6: 8864. PMID 26602609 DOI: 10.1038/Ncomms9864  0.141
2017 Scheel TKH, Moore MJ, Luna JM, Nishiuchi E, Fak J, Darnell RB, Rice CM. Global mapping of miRNA-target interactions in cattle (Bos taurus). Scientific Reports. 7: 8190. PMID 28811507 DOI: 10.1038/S41598-017-07880-8  0.139
2005 Blachère NE, Darnell RB, Albert ML. Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation. Plos Biology. 3: e185. PMID 15839733 DOI: 10.1371/journal.pbio.0030185  0.139
2006 Darnell RB, Posner JB. Paraneoplastic syndromes affecting the nervous system. Seminars in Oncology. 33: 270-98. PMID 16769417 DOI: 10.1053/j.seminoncol.2006.03.008  0.138
2012 Loeb GB, Khan AA, Canner D, Hiatt JB, Shendure J, Darnell RB, Leslie CS, Rudensky AY. Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting. Molecular Cell. 48: 760-70. PMID 23142080 DOI: 10.1016/J.Molcel.2012.10.002  0.131
2012 Riley KJ, Rabinowitz GS, Yario TA, Luna JM, Darnell RB, Steitz JA. EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency. The Embo Journal. 31: 2207-21. PMID 22473208 DOI: 10.1038/Emboj.2012.63  0.13
2023 Taylor SR, Kobayashi M, Vilella A, Tiwari D, Zolboot N, Du JX, Spencer KR, Hartzell A, Girgiss C, Abaci YT, Shao Y, De Sanctis C, Bellenchi GC, Darnell RB, Gross C, et al. MicroRNA-218 instructs proper assembly of hippocampal networks. Elife. 12. PMID 37862092 DOI: 10.7554/eLife.82729  0.129
2001 Albert ML, Jegathesan M, Darnell RB. Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nature Immunology. 2: 1010-7. PMID 11590405 DOI: 10.1038/ni722  0.128
2007 Longman RS, Braun D, Pellegrini S, Rice CM, Darnell RB, Albert ML. Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation. Blood. 109: 1113-22. PMID 17018853 DOI: 10.1182/Blood-2006-05-023465  0.124
2004 Orange DE, Jegathesan M, Blachère NE, Frank MO, Scher HI, Albert ML, Darnell RB. Effective antigen cross-presentation by prostate cancer patients' dendritic cells: implications for prostate cancer immunotherapy. Prostate Cancer and Prostatic Diseases. 7: 63-72. PMID 14999241 DOI: 10.1038/sj.pcan.4500694  0.122
1986 Darnell RB, Boime I. Differential expression of the human gonadotropin alpha gene in ectopic and eutopic cells. Molecular and Cellular Biology. 5: 3157-67. PMID 2427926 DOI: 10.1128/MCB.5.11.3157  0.122
2023 Bai Z, Bartelo N, Aslam M, Hale C, Blachere NE, Parveen S, Spolaore E, DiCarlo E, Gravallese E, Smith MH, Frank MO, Jiang CS, Zhang H, Lewis MJ, Sikandar S, ... ... Darnell R, et al. Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis. Medrxiv : the Preprint Server For Health Sciences. PMID 37662384 DOI: 10.1101/2023.08.17.23294232  0.12
2019 Wrzeszczynski KO, Rahman S, Frank MO, Arora K, Shah M, Geiger H, Felice V, Manaa D, Dikoglu E, Khaira D, Chimpiri AR, Michelini VV, Jobanputra V, Darnell RB, Powers S, et al. Identification of targetable BRAF ΔN486_P490 variant by whole genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma. Cold Spring Harbor Molecular Case Studies. PMID 31519698 DOI: 10.1101/mcs.a004424  0.114
2017 Luna JM, Barajas JM, Teng KY, Sun HL, Moore MJ, Rice CM, Darnell RB, Ghoshal K. Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer. Molecular Cell. PMID 28735896 DOI: 10.1016/J.Molcel.2017.06.025  0.111
2014 Freudenberg-Hua Y, Freudenberg J, Vacic V, Abhyankar A, Emde AK, Ben-Avraham D, Barzilai N, Oschwald D, Christen E, Koppel J, Greenwald B, Darnell RB, Germer S, Atzmon G, Davies P. Disease variants in genomes of 44 centenarians. Molecular Genetics & Genomic Medicine. 2: 438-50. PMID 25333069 DOI: 10.1002/Mgg3.86  0.107
2015 Luna JM, Scheel TK, Danino T, Shaw KS, Mele A, Fak JJ, Nishiuchi E, Takacs CN, Catanese MT, de Jong YP, Jacobson IM, Rice CM, Darnell RB. Hepatitis C virus RNA functionally sequesters miR-122. Cell. 160: 1099-110. PMID 25768906 DOI: 10.1016/J.Cell.2015.02.025  0.106
2018 Wrzeszczynski KO, Felice V, Shah M, Rahman S, Emde AK, Jobanputra V, O Frank M, Darnell RB. Whole Genome Sequencing-Based Discovery of Structural Variants in Glioblastoma. Methods in Molecular Biology (Clifton, N.J.). 1741: 1-29. PMID 29392687 DOI: 10.1007/978-1-4939-7659-1_1  0.105
2006 Blachère NE, Morris HK, Braun D, Saklani H, Di Santo JP, Darnell RB, Albert ML. IL-2 is required for the activation of memory CD8+ T cells via antigen cross-presentation. Journal of Immunology (Baltimore, Md. : 1950). 176: 7288-300. PMID 16751372  0.104
2014 Frank MO, Kaufman J, Parveen S, Blachère NE, Orange DE, Darnell RB. Dendritic cell vaccines containing lymphocytes produce improved immunogenicity in patients with cancer. Journal of Translational Medicine. 12: 338. PMID 25475068 DOI: 10.1186/s12967-014-0338-3  0.104
2012 Orange D, Frank M, Tian S, Dousmanis A, Marmur R, Buckley N, Parveen S, Graber JJ, Blachère N, Darnell RB. Cellular immune suppression in paraneoplastic neurologic syndromes targeting intracellular antigens. Archives of Neurology. 69: 1132-40. PMID 22566506 DOI: 10.1001/archneurol.2012.595  0.103
2021 Frank MO, Blachere NE, Parveen S, Hacisuleyman E, Fak J, Luna JM, Michailidis E, Wright S, Stark P, Campbell A, Foo A, Sakmar TP, Huffman V, Bergh M, Goldfarb A, ... ... Darnell RB, et al. DRUL for school: Opening Pre-K with safe, simple, sensitive saliva testing for SARS-CoV-2. Plos One. 16: e0252949. PMID 34170927 DOI: 10.1371/journal.pone.0252949  0.101
2018 Mak AC, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, ... ... Darnell RB, et al. Whole Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 29509491 DOI: 10.1164/Rccm.201712-2529Oc  0.101
2004 Whelan BM, Murdoch BE, Theodoros DG, Darnell R, Silburn P, Hall B. Redefining functional models of basal ganglia organization: role for the posteroventral pallidum in linguistic processing? Movement Disorders : Official Journal of the Movement Disorder Society. 19: 1267-78. PMID 15390054 DOI: 10.1002/mds.20252  0.099
2020 Hadi K, Yao X, Behr JM, Deshpande A, Xanthopoulakis C, Tian H, Kudman S, Rosiene J, Darmofal M, DeRose J, Mortensen R, Adney EM, Shaiber A, Gajic Z, Sigouros M, ... ... Darnell RB, et al. Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs. Cell. 183: 197-210.e32. PMID 33007263 DOI: 10.1016/j.cell.2020.08.006  0.095
2019 Frank MO, Koyama T, Rhrissorrakrai K, Robine N, Utro F, Emde AK, Chen BJ, Arora K, Shah M, Geiger H, Felice V, Dikoglu E, Rahman S, Fang A, Vacic V, ... ... Darnell RB, et al. Sequencing and curation strategies for identifying candidate glioblastoma treatments. Bmc Medical Genomics. 12: 56. PMID 31023376 DOI: 10.1186/S12920-019-0500-0  0.09
2023 Brewer RC, Lanz TV, Hale CR, Sepich-Poore GD, Martino C, Swafford AD, Carroll TS, Kongpachith S, Blum LK, Elliott SE, Blachere NE, Parveen S, Fak J, Yao V, Troyanskaya O, ... ... Darnell RB, et al. Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Science Translational Medicine. 15: eabq8476. PMID 36812347 DOI: 10.1126/scitranslmed.abq8476  0.089
2000 Albert ML, Austin LM, Darnell RB. Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration Annals of Neurology. 47: 9-17. DOI: 10.1002/1531-8249(200001)47:1<9::AID-ANA5>3.0.CO;2-I  0.088
2015 Pendleton M, Sebra R, Pang AW, Ummat A, Franzen O, Rausch T, Stütz AM, Stedman W, Anantharaman T, Hastie A, Dai H, Fritz MH, Cao H, Cohain A, Deikus G, ... ... Darnell RB, et al. Assembly and diploid architecture of an individual human genome via single-molecule technologies. Nature Methods. PMID 26121404 DOI: 10.1038/Nmeth.3454  0.088
1987 Boime I, Boothby M, Darnell RB, Policastro P. Structure and expression of human placental hormone genes. Advances in Experimental Medicine and Biology. 205: 267-80. PMID 3788716 DOI: 10.1007/978-1-4684-5209-9_12  0.08
2010 Kakumoto K, Miyazaki T, Watanabe M, Darnell RB, Okano H, Okano H. The maintenance of Purkinje axons by HuC in adult cerebellum Neuroscience Research. 68: e61. DOI: 10.1016/J.Neures.2010.07.038  0.079
2010 Frank MO, Kaufman J, Tian S, Suárez-Fariñas M, Parveen S, Blachère NE, Morris MJ, Slovin S, Scher HI, Albert ML, Darnell RB. Harnessing naturally occurring tumor immunity: a clinical vaccine trial in prostate cancer. Plos One. 5. PMID 20824184 DOI: 10.1371/Journal.Pone.0012367  0.079
2003 Darnell RB. Memory, Synaptic Translation, and...Prions? Cell. 115: 767-768. PMID 14697195 DOI: 10.1016/S0092-8674(03)01022-5  0.078
2013 Foster SD, Givens GH, Dornan GJ, Dunstan PK, Darnell R. Modelling biological regions from multi-species and environmental data Environmetrics. 24: 489-499. DOI: 10.1002/Env.2245  0.077
2007 Jull G, Amiri M, Bullock-Saxton J, Darnell R, Lander C. Cervical musculoskeletal impairment in frequent intermittent headache. Part 1: Subjects with single headaches. Cephalalgia : An International Journal of Headache. 27: 793-802. PMID 17598761 DOI: 10.1111/j.1468-2982.2007.01345.x  0.076
2000 Darnell RB, Albert ML. cdr2-Specific CTLs are detected in the blood of all patients with paraneoplastic cerebellar degeneration analyzed Annals of Neurology. 48: 270-270. DOI: 10.1002/1531-8249(200008)48:2<270::AID-ANA25>3.0.CO;2-Y  0.075
2013 Younger DS, Graber J, Hayakawa-Yano Y, Parveen S, Frank M, Darnell RB. Ri/Nova gene-associated paraneoplastic subacute motor neuronopathy. Muscle & Nerve. 47: 617-8. PMID 23463350 DOI: 10.1002/mus.23783  0.075
2004 Spann TM, Williamson JG, Darnell RL. Photoperiod and temperature effects on growth and carbohydrate storage in southern highbush blueberry interspecific hybrid Journal of the American Society For Horticultural Science. 129: 294-298. DOI: 10.21273/Jashs.129.3.0294  0.074
2017 Wrzeszczynski KO, Frank MO, Koyama T, Rhrissorrakrai K, Robine N, Utro F, Emde AK, Chen BJ, Arora K, Shah M, Vacic V, Norel R, Bilal E, Bergmann EA, Moore Vogel JL, ... ... Darnell RB, et al. Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma. Neurology. Genetics. 3: e164. PMID 28740869 DOI: 10.1212/Nxg.0000000000000164  0.074
2004 Albert ML, Darnell RB. Paraneoplastic neurological degenerations: Keys to tumour immunity Nature Reviews Cancer. 4: 36-44. PMID 14708025  0.071
2020 Orange DE, Darnell RB. PRIME Cells Predicting Rheumatoid Arthritis Flares. Reply. The New England Journal of Medicine. 383: 1595-1596. PMID 33053295 DOI: 10.1056/NEJMc2027492#sa3  0.07
2011 Darnell R. Reassessing the contribution of Franz Boas (1858-1941): Conference report Historiographia Linguistica. 38: 253-254. DOI: 10.1075/Hl.38.1-2.18Dar  0.064
2012 Darnell RL, Cruz-Huerta N, Williamson JG. Night temperature and source-sink effects on overall growth, cell number and cell size in bell pepper ovaries. Annals of Botany. 110: 987-94. PMID 22933415 DOI: 10.1093/Aob/Mcs173  0.062
2005 Sterling M, Jull G, Vicenzino B, Kenardy J, Darnell R. Physical and psychological factors predict outcome following whiplash injury. Pain. 114: 141-8. PMID 15733639 DOI: 10.1016/j.pain.2004.12.005  0.062
2007 Amiri M, Jull G, Bullock-Saxton J, Darnell R, Lander C. Cervical musculoskeletal impairment in frequent intermittent headache. Part 2: subjects with concurrent headache types. Cephalalgia : An International Journal of Headache. 27: 891-8. PMID 17608813 DOI: 10.1111/j.1468-2982.2007.01346.x  0.061
2003 Darnell RB, Posner JB. Observing the invisible: successful tumor immunity in humans. Nature Immunology. 4: 201. PMID 12605223 DOI: 10.1038/ni0303-201  0.061
2003 Darnell RB, Posner JB. Paraneoplastic syndromes involving the nervous system. The New England Journal of Medicine. 349: 1543-54. PMID 14561798 DOI: 10.1056/NEJMra023009  0.061
2018 Orange DE, Agius P, DiCarlo EF, Robine N, Geiger H, Szymonifka J, McNamara M, Cummings R, Andersen KM, Mirza S, Figgie M, Ivashkiv L, Pernis AB, Jiang C, Frank M, ... Darnell R, et al. Machine learning integration of rheumatoid arthritis synovial histology and RNAseq data identifies three disease subtypes. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29468833 DOI: 10.1002/Art.40428  0.059
2015 Kovaleski AP, Williamson JG, Olmstead JW, Darnell RL. Inflorescence bud initiation, development, and bloom in two southern highbush blueberry cultivars Journal of the American Society For Horticultural Science. 140: 38-44.  0.059
1993 Darnell RB. The polymerase chain reaction: application to nervous system disease. Annals of Neurology. 34: 513-23. PMID 7692807 DOI: 10.1002/ana.410340404  0.058
2021 Mouncey PR, Richards-Belle A, Thomas K, Harrison DA, Sadique MZ, Grieve RD, Camsooksai J, Darnell R, Gordon AC, Henry D, Hudson N, Mason AJ, Saull M, Whitman C, Young JD, et al. Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT. Health Technology Assessment (Winchester, England). 25: 1-90. PMID 33648623 DOI: 10.3310/hta25140  0.057
2006 Cooke DM, McKenna K, Fleming J, Darnell R. Criterion validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST). Scandinavian Journal of Occupational Therapy. 13: 38-48. PMID 16615414 DOI: 10.1080/11038120500363006  0.057
2021 Hacisuleyman E, Hale C, Saito Y, Blachere NE, Bergh M, Conlon EG, Schaefer-Babajew DJ, DaSilva J, Muecksch F, Gaebler C, Lifton R, Nussenzweig MC, Hatziioannou T, Bieniasz PD, Darnell RB. Vaccine Breakthrough Infections with SARS-CoV-2 Variants. The New England Journal of Medicine. PMID 33882219 DOI: 10.1056/NEJMoa2105000  0.056
2007 Darnell RB. NMDA receptor as a target in paraneoplastic encephalitis. Annals of Neurology. 61: 3-4. PMID 17262845 DOI: 10.1002/ana.21074  0.056
2012 Landis SC, Amara SG, Asadullah K, Austin CP, Blumenstein R, Bradley EW, Crystal RG, Darnell RB, Ferrante RJ, Fillit H, Finkelstein R, Fisher M, Gendelman HE, Golub RM, Goudreau JL, et al. A call for transparent reporting to optimize the predictive value of preclinical research. Nature. 490: 187-91. PMID 23060188 DOI: 10.1038/Nature11556  0.054
2009 Allen J, Bisbee PA, Darnell RL, Kuang A, Levine LH, Musgrave ME, van Loon JJ. Gravity control of growth form in Brassica rapa and Arabidopsis thaliana (Brassicaceae): Consequences for secondary metabolism. American Journal of Botany. 96: 652-60. PMID 21628221 DOI: 10.3732/ajb.0800261  0.053
1999 Darnell RB. The importance of defining the paraneoplastic neurologic disorders. The New England Journal of Medicine. 340: 1831-3. PMID 10362830 DOI: 10.1056/NEJM199906103402311  0.051
2009 Darnell RB, Posner JB. Autoimmune encephalopathy: the spectrum widens. Annals of Neurology. 66: 1-2. PMID 19670434 DOI: 10.1002/ana.21759  0.051
2016 Roberts WK, Blachère NE, Frank MO, Dousmanis A, Ransohoff RM, Darnell RB. The role of CSF CXCL10 in paraneoplastic neurologic disorders. Annals of Neurology. PMID 27669487 DOI: 10.1002/ana.24784  0.05
2016 Shimadzu H, Foster SD, Darnell R. Imperfect observations in ecological studies Environmental and Ecological Statistics. 1-22. DOI: 10.1007/s10651-016-0342-2  0.048
2017 Shukla N, Roberts SS, Baki MO, Mushtaq Q, Goss PE, Park BH, Gundem G, Tian K, Geiger H, Redfield K, Behr G, Benayed R, Zehir A, Hechtman JF, Darnell RB, et al. Successful Targeted Therapy of Refractory PediatricFusion-Positive Secretory Breast Carcinoma. Jco Precision Oncology. 2017. PMID 29623306 DOI: 10.1200/PO.17.00034  0.046
2010 Collins NJ, Crossley KM, Darnell R, Vicenzino B. Predictors of short and long term outcome in patellofemoral pain syndrome: a prospective longitudinal study. Bmc Musculoskeletal Disorders. 11: 11. PMID 20082723 DOI: 10.1186/1471-2474-11-11  0.045
2015 Kovaleski AP, Williamson JG, Casamali B, Darnell RL. Effects of timing and intensity of summer pruning on vegetative traits of two southern highbush blueberry cultivars Hortscience. 50: 68-73.  0.044
2009 Grimaldi A, Richardson C, Durbridge G, Donnelly W, Darnell R, Hides J. The association between degenerative hip joint pathology and size of the gluteus maximus and tensor fascia lata muscles. Manual Therapy. 14: 611-7. PMID 19121974 DOI: 10.1016/j.math.2008.11.002  0.044
2022 Darnell R, Newell C, Edwards J, Gendall E, Harrison D, Sprinckmoller S, Mouncey P, Gould D, Thomas M. Critical illness-related cardiac arrest: Protocol for an investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom. Journal of the Intensive Care Society. 23: 493-497. PMID 36751345 DOI: 10.1177/17511437211055899  0.043
2014 Nunez GH, Kovaleski AP, Darnell RL. Formal education can affect students' perception of organic produce Horttechnology. 24: 64-70. DOI: 10.21273/Horttech.24.1.64  0.042
2007 Whiting E, Chenery H, Chalk J, Darnell R, Copland D. Dexamphetamine enhances explicit new word learning for novel objects. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 805-16. PMID 17250775 DOI: 10.1017/S1461145706007516  0.042
2019 Frank MO, Koyama T, Rhrissorrakrai K, Robine N, Utro F, Emde AK, Chen BJ, Arora K, Shah M, Geiger H, Felice V, Dikoglu E, Rahman S, Fang X, Vacic V, ... ... Darnell RB, et al. Correction to: Sequencing and curation strategies for identifying candidate glioblastoma treatments. Bmc Medical Genomics. 12: 114. PMID 31375115 DOI: 10.1186/S12920-019-0563-Y  0.042
2006 Elliott J, Jull G, Noteboom JT, Darnell R, Galloway G, Gibbon WW. Fatty infiltration in the cervical extensor muscles in persistent whiplash-associated disorders: a magnetic resonance imaging analysis. Spine. 31: E847-55. PMID 17047533 DOI: 10.1097/01.brs.0000240841.07050.34  0.041
2011 Cruz-Huerta N, Williamson JG, Darnell RL. Low night temperature increases ovary size in sweet pepper cultivars Hortscience. 46: 396-401. DOI: 10.21273/Hortsci.46.3.396  0.041
2006 Cooke DM, McKenna K, Fleming J, Darnell R. Construct and ecological validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST). Scandinavian Journal of Occupational Therapy. 13: 49-61. PMID 16615415 DOI: 10.1080/11038120500363014  0.04
2005 Goozée JV, Stephenson DK, Murdoch BE, Darnell RE, Lapointe LL. Lingual kinematic strategies used to increase speech rate: comparison between younger and older adults. Clinical Linguistics & Phonetics. 19: 319-34. PMID 16019778 DOI: 10.1080/02699200420002268862  0.039
2011 Percival DB, Lennox SM, Wang YG, Darnell RE. Wavelet-based multiresolution analysis of Wivenhoe Dam water temperatures Water Resources Research. 47. DOI: 10.1029/2010Wr009657  0.038
2006 Wilson WJ, Chapple JA, Phillips KM, Snell KT, Bradley AP, Darnell R. Over-complete discrete wavelet transformation of the normal auditory brainstem response improves prediction of outcome following severe acute closed head injury. Audiology & Neuro-Otology. 11: 249-58. PMID 16679759 DOI: 10.1159/000093111  0.037
2008 Darnell R. Benedictine visionings of southwestern cultural diversity beyond relativism Journal of Anthropological Research. 64: 469-482. DOI: 10.3998/Jar.0521004.0064.402  0.036
2008 Vicenzino B, Collins N, Crossley K, Beller E, Darnell R, McPoil T. Foot orthoses and physiotherapy in the treatment of patellofemoral pain syndrome: a randomised clinical trial. Bmc Musculoskeletal Disorders. 9: 27. PMID 18304317 DOI: 10.1186/1471-2474-9-27  0.036
2008 Treleaven J, LowChoy N, Darnell R, Panizza B, Brown-Rothwell D, Jull G. Comparison of sensorimotor disturbance between subjects with persistent whiplash-associated disorder and subjects with vestibular pathology associated with acoustic neuroma. Archives of Physical Medicine and Rehabilitation. 89: 522-30. PMID 18295632 DOI: 10.1016/j.apmr.2007.11.002  0.036
2013 Henley P, Jahedmotlagh Z, Thomson S, Hill J, Darnell R, Jacobs D, Johnson J, Williams NC, Williams RM, Van Uum S, Bend JR, Koren G. Hair cortisol as a biomarker of stress among a first nation in Canada. Therapeutic Drug Monitoring. 35: 595-9. PMID 24052063 DOI: 10.1097/Ftd.0B013E318292Eb84  0.036
2008 Elliott J, Sterling M, Noteboom JT, Darnell R, Galloway G, Jull G. Fatty infiltrate in the cervical extensor muscles is not a feature of chronic, insidious-onset neck pain. Clinical Radiology. 63: 681-7. PMID 18455560 DOI: 10.1016/j.crad.2007.11.011  0.035
2012 Darnell R, Henderson B, Kroon FJ, Kuhnert P. Statistical power of detecting trends in total suspended sediment loads to the Great Barrier Reef. Marine Pollution Bulletin. 65: 203-9. PMID 22551850 DOI: 10.1016/j.marpolbul.2012.04.002  0.034
2015 Shimadzu H, Darnell R. Attenuation of species abundance distributions by sampling. Royal Society Open Science. 2: 140219. PMID 26064626 DOI: 10.1098/rsos.140219  0.034
2015 Darnell R, Hamilton M, Hancock RLA, Smith J. The Franz Boas papers, volume 1: Franz Boas as public intellectual—theory, ethnography, activism The Franz Boas Papers, Volume 1: Franz Boas as Public Intellectual-Theory, Ethnography, Activism. 1-382.  0.034
2008 Whiting E, Chenery HJ, Chalk J, Darnell R, Copland DA. The explicit learning of new names for known objects is improved by dexamphetamine. Brain and Language. 104: 254-61. PMID 17428528 DOI: 10.1016/j.bandl.2007.03.003  0.033
2007 Alvarado-Raya HE, Darnell RL, Williamson JG. Root to shoot relations in an annual raspberry (Rubus idaeus L.) production system Hortscience. 42: 1559-1562. DOI: 10.21273/Hortsci.42.7.1559  0.033
2015 Darnell R. Recent Trends in Northwestern America Reviews in Anthropology. 44: 237-253. DOI: 10.1080/00938157.2015.1113729  0.032
2004 Woodyatt G, Marinac J, Darnell R, Sigafoos J, Halle J. Behaviour state analysis in Rett syndrome: Continuous data reliability measurement International Journal of Disability, Development and Education. 51: 383-400. DOI: 10.1080/1034912042000295035  0.031
2007 Desha LN, Ziviani JM, Nicholson JM, Martin G, Darnell RE. Physical activity and depressive symptoms in American adolescents. Journal of Sport & Exercise Psychology. 29: 534-43. PMID 17968052  0.03
2008 Johnston V, Jull G, Darnell R, Jimmieson NL, Souvlis T. Alterations in cervical muscle activity in functional and stressful tasks in female office workers with neck pain. European Journal of Applied Physiology. 103: 253-64. PMID 18293008 DOI: 10.1007/s00421-008-0696-8  0.03
2022 Ramnarayan P, Richards-Belle A, Drikite L, Saull M, Orzechowska I, Darnell R, Sadique Z, Lester J, Morris KP, Tume LN, Davis PJ, Peters MJ, Feltbower RG, Grieve R, Thomas K, et al. Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial. Jama. PMID 35390113 DOI: 10.1001/jama.2022.3367  0.029
1993 Darnell RB, Arbit E. Reversible diencephalic dysfunction: episodic hyperhidrosis due to a trapped third ventricle. Neurology. 43: 579-82. PMID 8451005 DOI: 10.1212/WNL.43.3_Part_1.579  0.029
2006 Pirouzi S, Hides J, Richardson C, Darnell R, Toppenberg R. Low back pain patients demonstrate increased hip extensor muscle activity during standardized submaximal rotation efforts. Spine. 31: E999-E1005. PMID 17172991 DOI: 10.1097/01.brs.0000250076.74366.9d  0.029
2022 Darnell R, Newell C, Edwards J, Gendall E, Harrison D, Sprinckmoller S, Mouncey P, Gould D, Thomas M. Critical illness related cardiac arrest: Protocol for an investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom. Journal of the Intensive Care Society. 24: 222-223. PMID 37260435 DOI: 10.1177/17511437221086890  0.028
2014 Darnell R. An elegy for a structuralist legacy: Lévi-Strauss, cultural relativism, and the universal capacities of the human mind Anthropologists and Their Traditions Across National Borders. 8: 173-181.  0.028
2006 Darnell RL, Brunner B, Alvarado HE, Williamson JG, Plaza M, Negrón E. Annual, off-season raspberry production in warm season climates Horttechnology. 16: 92-97. DOI: 10.21273/Horttech.16.1.0092  0.028
2014 Henley P, Lowthers M, Koren G, Fedha PT, Russell E, VanUum S, Arya S, Darnell R, Creed IF, Trick CG, Bend JR. Cultural and socio-economic conditions as factors contributing to chronic stress in sub-Saharan African communities. Canadian Journal of Physiology and Pharmacology. 92: 725-32. PMID 25083791 DOI: 10.1139/Cjpp-2014-0035  0.028
2020 Lamontagne F, Richards-Belle A, Thomas K, Harrison DA, Sadique MZ, Grieve RD, Camsooksai J, Darnell R, Gordon AC, Henry D, Hudson N, Mason AJ, Saull M, Whitman C, Young JD, et al. Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial. Jama. PMID 32049269 DOI: 10.1001/jama.2020.0930  0.026
2012 Darnell R. The nature of knowledge: Calibrating discourses across cultures and finding common disciplinary ground Journal of Canadian Studies. 46: 26-44.  0.025
2013 Darnell RL, Cruz-Huerta N, Williamson JG. Night temperature and source-sink effects on growth, leaf carbon exchange rate, and carbohydrate accumulation in bell pepper ovaries Journal of the American Society For Horticultural Science. 138: 331-337. DOI: 10.21273/Jashs.138.5.331  0.025
2011 Darnell RL, Cruz-Huerta N. Uptake and assimilation of nitrate and iron in cultivated and wild Vaccinium species International Journal of Fruit Science. 11: 136-150. DOI: 10.1080/15538362.2011.578518  0.025
2022 Ramnarayan P, Richards-Belle A, Drikite L, Saull M, Orzechowska I, Darnell R, Sadique Z, Lester J, Morris KP, Tume LN, Davis PJ, Peters MJ, Feltbower RG, Grieve R, Thomas K, et al. Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units: A Randomized Clinical Trial. Jama. PMID 35707984 DOI: 10.1001/jama.2022.9615  0.024
2006 Cooke DM, Mckenna K, Fleming J, Darnell R. Australian normative data for the Occupational Therapy Adult Perceptual Screening Test Australian Occupational Therapy Journal. 53: 325-336. DOI: 10.1111/j.1440-1630.2006.00597.x  0.024
2009 Darnell R. Part 4: The human in culture anthropological approaches to human nature, cultural relativism and ethnocentrism Anthropologica. 51: 187-194.  0.024
2009 Darnell R. Cross-cultural constructions of work, leisure and community responsibility: Some First Nations reflections Journal of Occupational Science. 16: 4-9. DOI: 10.1080/14427591.2009.9686634  0.024
2007 Darnell R. Languages: Linguistic Change and the Study of Indian Languages from Colonial Times to the Present A Companion to American Indian History. 173-192. DOI: 10.1002/9780470996461.ch11  0.023
2013 Altindis E, Alpar MA, Aksay E, Beckwith J, Bökel C, Curl RF, Darnell RB, Elledge SJ, Erman B, Frahm J, Goff SP, Greengard P, Hoffmann R, Ilhan B, Kaslin J, et al. Turkey must end violent response to protests. Science (New York, N.Y.). 341: 236. PMID 23869001 DOI: 10.1126/Science.341.6143.236-A  0.023
2015 Nunez GH, Olmstead JW, Darnell RL. Rhizosphere acidification is not part of the strategy I iron deficiency response of Vaccinium arboreum and the southern highbush blueberry Hortscience. 50: 1064-1069. DOI: 10.21273/Hortsci.50.7.1064  0.023
2005 Cooke DM, McKenna K, Fleming J, Darnell R. The reliability of the Occupational Therapy Adult Perceptual Screening Test (OT-APST) British Journal of Occupational Therapy. 68: 509-517.  0.022
2009 Collins N, Crossley K, Beller E, Darnell R, McPoil T, Vicenzino B. Foot orthoses and physiotherapy in the treatment of patellofemoral pain syndrome: randomised clinical trial. British Journal of Sports Medicine. 43: 169-71. PMID 19270165 DOI: 10.1136/bmj.a1735  0.022
2006 Darnell RL, Hiss SA. Uptake and assimilation of nitrate and iron in two Vaccinium species as affected by external nitrate concentration Journal of the American Society For Horticultural Science. 131: 5-10. DOI: 10.21273/Jashs.131.1.5  0.022
2006 Harvey LA, Wilson WJ, Darnell R, Bradley AP, Baker FC. The effect of sleep on the fast and slow components of the auditory brainstem response: A case study Australian and New Zealand Journal of Audiology. 28: 106-121.  0.02
2008 Kei J, Smith D, Joseph S, Stopa J, Kang S, Darnell R. Effects of ambient acoustic noise on the auditory steady-state response thresholds in normally hearing adults. Audiology & Neuro-Otology. 13: 13-8. PMID 17715465 DOI: 10.1159/000107433  0.019
2008 Darnell RL, Alvarado-Raya HE, Williamson JG. Root pruning effects on growth and yield of red raspberry Hortscience. 43: 681-684. DOI: 10.21273/Hortsci.43.3.681  0.019
2011 Darnell R. 2009 presidential address: What is "history"? An anthropologist's eye view Ethnohistory. 58: 213-227. DOI: 10.1215/00141801-1163019  0.019
2021 Blachere NE, Hacisuleyman E, Darnell RB. Vaccine Breakthrough Infections with SARS-CoV-2 Variants. Reply. The New England Journal of Medicine. PMID 34077642 DOI: 10.1056/NEJMc2107808#sa3  0.018
2006 Darnell R. Franz Boas: Scientist and public intellectual Visionary Observers: Anthropological Inquiry and Education. 1-23.  0.017
2011 Darnell R. The paradoxical legacy of postmodernism Anthropologica. 53: 328-330.  0.016
2004 Poonnachit U, Darnell R. Effect of ammonium and nitrate on ferric chelate reductase and nitrate reductase in Vaccinium species Annals of Botany. 93: 399-405. PMID 14980973 DOI: 10.1093/Aob/Mch053  0.016
2014 Darnell R, Gleach FW. Editors' Introduction Anthropologists and Their Traditions Across National Borders. 8: ix-xi.  0.016
2014 Ridoutt BG, Baird DL, Bastiaans K, Darnell R, Hendrie GA, Riley M, Sanguansri P, Syrette J, Noakes M, Keating BA. Short communication: a food-systems approach to assessing dairy product waste. Journal of Dairy Science. 97: 6107-10. PMID 25064645 DOI: 10.3168/jds.2014-8017  0.016
2016 Paranhos LG, Barrett CE, Zotarelli L, Darnell R, Migliaccio K, Borisova T. Planting date and in-row plant spacing effects on growth and yield of cabbage under plastic mulch Scientia Horticulturae. 202: 49-56. DOI: 10.1016/J.Scienta.2016.02.022  0.015
2011 Peterson EE, Sheldon F, Darnell R, Bunn SE, Harch BD. A comparison of spatially explicit landscape representation methods and their relationship to stream condition Freshwater Biology. 56: 590-610. DOI: 10.1111/j.1365-2427.2010.02507.x  0.015
2005 Darnell RB, Posner JB. A new cause of limbic encephalopathy. Brain : a Journal of Neurology. 128: 1745-6. PMID 16030181 DOI: 10.1093/brain/awh592  0.014
2015 Darnell R. 2014 weaver-tremblay award winner applied anthropology: Disciplinary oxymoron? Anthropologica. 57: 1-11.  0.013
2005 Darnell R. Linguistic anthropology in Canada: Some personal reflections Canadian Journal of Linguistics. 50: 151-172+319. DOI: 10.1353/Cjl.2007.0003  0.012
2006 Darnell R. Keeping the faith: A legacy of native american ethnography, ethnohistory, and psychology New Perspectives On Native North America. 3-16.  0.011
2008 Stephens CV, Darnell R. The interdisciplines of ecosystem health: As revealed in First Nations collaborations International Journal of Interdisciplinary Social Sciences. 3: 147-159. DOI: 10.18848/1833-1882/Cgp/V03I01/52477  0.011
2012 Foster SD, Shimadzu H, Darnell R. Uncertainty in spatially predicted covariates: Is it ignorable? Journal of the Royal Statistical Society. Series C: Applied Statistics. 61: 637-652. DOI: 10.1111/j.1467-9876.2011.01030.x  0.011
2015 Darnell RL, Casamali B, Williamson JG. Nutrient assimilation in southern highbush blueberry and implications for the field Horttechnology. 25: 460-463. DOI: 10.21273/Horttech.25.4.460  0.011
2016 Casamali B, Darnell RL, Kovaleski AP, Olmstead JW, Williamson JG. Vegetative and reproductive traits of two southern highbush blueberry cultivars grafted onto Vaccinium arboreum rootstocks Hortscience. 51: 880-886.  0.01
2015 Scheckel C, Darnell RB. Microexons--tiny but mighty. The Embo Journal. 34: 273-4. PMID 25535247 DOI: 10.15252/embj.201490651  0.01
2015 Kovaleski AP, Darnell RL, Casamali B, Williamson JG. Effects of timing and intensity of summer pruning on reproductive traits of two southern highbush blueberry cultivars Hortscience. 50: 1486-1491. DOI: 10.21273/Hortsci.50.10.1486  0.01
2015 Darnell RM. The American sea: A natural history of the gulf of Mexico The American Sea: a Natural History of the Gulf of Mexico. 1-557.  0.01
2014 Aldous DE, Dixon GR, Darnell RL, Pratley JE. Education and training futures in horticulture and horticultural science Horticulture: Plants For People and Places. 3: 1087-1115. DOI: 10.1007/978-94-017-8560-0_6  0.01
2014 Darnell R, Gleach FW. Anthropologists and their traditions across national borders: Histories of anthropology annual Anthropologists and Their Traditions Across National Borders. 8: 1-279.  0.01
2013 Darnell R, Murray SO. Series editors' introduction Racial Science in Hitler's New Europe, 1938-1945. ix.  0.01
2013 Darnell R, Murray SO. Series editors' introduction Racial Science in Hitler's New Europe, 1938-1945. ix.  0.01
2011 Dunstan PK, Foster SD, Darnell R. Model based grouping of species across environmental gradients Ecological Modelling. 222: 955-963. DOI: 10.1016/j.ecolmodel.2010.11.030  0.01
2010 Lofland MH, Darnell R. How do you accommodate morbidly obese patients? Ons Connect. 25: 11. PMID 21214083  0.01
2010 Darnell R. On disrobing those who would dismantle the aboriginal industry Anthropologica. 52: 206-207.  0.01
2008 Darnell R. First nations identity, contemporary interpretive communities, and nomadic legacies Arcadia. 43: 102-113. DOI: 10.1515/Arca.2008.009  0.01
2006 Bisset L, Beller E, Jull G, Brooks P, Darnell R, Vicenzino B. Mobilisation with movement and exercise, corticosteroid injection, or wait and see for tennis elbow: randomised trial. Bmj (Clinical Research Ed.). 333: 939. PMID 17012266 DOI: 10.1136/bmj.38961.584653.AE  0.01
2006 Darnell R. Benjamin Lee Whorf and the Boasian foundations of contemporary ethnolinguistics Language, Culture, and Society: Key Topics in Linguistic Anthropology. 82-95. DOI: 10.1017/CBO9780511616792.004  0.01
2005 Hess SA, Richardson C, Darnell R, Friis P, Lisle D, Myers P. Timing of rotator cuff activation during shoulder external rotation in throwers with and without symptoms of pain. The Journal of Orthopaedic and Sports Physical Therapy. 35: 812-20. PMID 16848102 DOI: 10.2519/jospt.2005.35.12.812  0.01
2005 Darnell RL, Cheek JG. Plant science graduate students: Demographics, research areas, and recruitment issues Horttechnology. 15: 677-681. DOI: 10.21273/Hortsci.40.4.1138B  0.01
2005 Jerome C, Darnell R, Oakley B, Pepe A. The effects of presence and time of exposure on simulator sickness Proceedings of the Human Factors and Ergonomics Society. 2258-2262.  0.01
2005 Lamb E, Darnell R, Hutchinson C, Simonne E, Webb M. Integrating organic and sustainable agriculture into a horticultural science curriculum Acta Horticulturae. 672: 197-203.  0.01
2004 Darnell R. Text, symbol, and tradition in Northwest Coast ethnology from Franz Boas to Claude Lévi-Strauss Coming to Shore: Northwest Coast Ethnology, Traditions, and Visions. 7-21.  0.01
2004 Darnell RL, Williamson JG, Alvarado HE. Off-season raspberry production in a sub-tropical climate Acta Horticulturae. 659: 67-71.  0.01
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