Jeffrey L. Noebels - Publications

Baylor College of Medicine, Houston, TX 
Neurogenetics, Basic Mechanisms of Epilepsy

225 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Massey CA, Thompson SJ, Ostrom RW, Drabek J, Sveinsson OA, Tomson T, Haas EA, Mena OJ, Goldman AM, Noebels JL. X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy. Brain Communications. 3: fcab149. PMID 34396109 DOI: 10.1093/braincomms/fcab149  1
2021 Buchanan GF, Gluckman BJ, Kalume FK, Lhatoo S, Maganti RK, Noebels JL, Simeone KA, Quigg MS, Pavlova MK. Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP. Epilepsy Currents. 15357597211004556. PMID 33787378 DOI: 10.1177/15357597211004556  1
2021 Aiba I, Noebels JL. Kcnq2/Kv7.2 controls the threshold and bihemispheric symmetry of cortical spreading depolarization. Brain : a Journal of Neurology. PMID 33768249 DOI: 10.1093/brain/awab141  1
2021 Loring KE, Mattiske T, Lee K, Zysk A, Jackson MR, Noebels JL, Shoubridge C. Early 17β-estradiol treatment reduces seizures but not abnormal behaviour in mice with expanded polyalanine tracts in the Aristaless related homeobox gene (ARX). Neurobiology of Disease. 105329. PMID 33711494 DOI: 10.1016/j.nbd.2021.105329  0.01
2020 Siehr M, Massey C, Noebels JL. Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-Linked Infantile Spasms Syndrome. Disease Models & Mechanisms. PMID 34005060 DOI: 10.1242/dmm.042515  0.01
2020 Liu CH, Seo R, Ho TS, Stankewich M, Mohler PJ, Hund TJ, Noebels JL, Rasband MN. β spectrin-dependent and domain specific mechanisms for Na channel clustering. Elife. 9. PMID 32425157 DOI: 10.7554/Elife.56629  0.04
2020 Hatcher A, Yu K, Meyer J, Aiba I, Deneen B, Noebels JL. Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model. The Journal of Clinical Investigation. PMID 32250339 DOI: 10.1172/Jci133316  1
2020 Siehr M, Massey C, Noebels JL. expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-Linked Infantile Spasms Syndrome. Disease Models & Mechanisms. PMID 32033960 DOI: 10.1242/dmm.042515  0.04
2020 Yu K, Lin CJ, Hatcher A, Lozzi B, Kong K, Huang-Hobbs E, Cheng YT, Beechar VB, Zhu W, Zhang Y, Chen F, Mills GB, Mohila CA, Creighton CJ, Noebels JL, et al. PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. Nature. PMID 31996845 DOI: 10.1038/S41586-020-1952-2  1
2020 Liu C, Seo R, Ho TS, Stankewich M, Mohler PJ, Hund TJ, Noebels JL, Rasband MN. Author response: β spectrin-dependent and domain specific mechanisms for Na+ channel clustering Elife. DOI: 10.7554/Elife.56629.Sa2  0.08
2019 Noebels JL. Predicting the impact of sodium channel mutations in human brain disease. Epilepsia. 60: S8-S16. PMID 31904123 DOI: 10.1111/epi.14724  0.01
2019 Miao QL, Herlitze S, Mark MD, Noebels JL. Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms. Brain : a Journal of Neurology. PMID 31800012 DOI: 10.1093/brain/awz365  1
2019 Chen CJ, Sgritta M, Mays J, Zhou H, Lucero R, Park J, Wang IC, Park JH, Kaipparettu BA, Stoica L, Jafar-Nejad P, Rigo F, Chin J, Noebels JL, Costa-Mattioli M. Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency. Nature Medicine. PMID 31636454 DOI: 10.1038/S41591-019-0608-Y  1
2019 Mahoney JM, Mills JD, Muhlebner A, Noebels J, Potschka H, Simonato M, Kobow K. 2017 WONOEP appraisal: Studying epilepsy as a network disease using systems biology approaches. Epilepsia. PMID 31087652 DOI: 10.1111/Epi.15216  0.01
2019 Aiba I, Noebels J. Adrenergic agonist induces rhythmic firing in quiescent cardiac preganglionic neurons in nucleus ambiguous via activation of intrinsic membrane excitability. Journal of Neurophysiology. PMID 30699052 DOI: 10.1152/Jn.00761.2018  1
2019 Noebels JL. Brainstem spreading depolarization: rapid descent into the shadow of SUDEP. Brain : a Journal of Neurology. 142: 231-233. PMID 30698758 DOI: 10.1093/brain/awy356  0.01
2018 Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, Miura E, Mazaki E, Ernst SJ, Cao D, Ohtani H, Itohara S, Yanagawa Y, Montal M, Yuzaki M, ... ... Noebels JL, et al. Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. Communications Biology. 1. PMID 30175250 DOI: 10.1038/s42003-018-0099-2  1
2018 Chen C, Holth JK, Bunton-Stasyshyn R, Anumonwo CK, Meisler MH, Noebels JL, Isom LL. deletion fails to rescue premature lethality in two models of sodium channel epilepsy. Annals of Clinical and Translational Neurology. 5: 982-987. PMID 30128323 DOI: 10.1002/Acn3.599  1
2018 Meyer J, Maheshwari A, Noebels J, Smirnakis S. Asynchronous suppression of visual cortex during absence seizures in stargazer mice. Nature Communications. 9: 1938. PMID 29769525 DOI: 10.1038/S41467-018-04349-8  1
2017 Moyer JT, Gnatkovsky V, Ono T, Otáhal J, Wagenaar J, Stacey WC, Noebels J, Ikeda A, Staley K, de Curtis M, Litt B, Galanopoulou AS. Standards for data acquisition and software-based analysis of in vivo electroencephalography recordings from animals. A TASK1-WG5 report of the AES/ILAE Translational Task Force of the ILAE. Epilepsia. 58: 53-67. PMID 29105070 DOI: 10.1111/Epi.13909  1
2017 Huang CY, Zhang C, Ho TS, Oses-Prieto J, Burlingame AL, Lalonde J, Noebels JL, Leterrier C, Rasband MN. αII spectrin forms a periodic cytoskeleton at the axon initial segment and is required for nervous system function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29038240 DOI: 10.1523/Jneurosci.2112-17.2017  1
2017 Maheshwari A, Akbar A, Wang M, Marks R, Yu K, Park S, Foster BL, Noebels JL. Persistent aberrant cortical phase-amplitude coupling following seizure treatment in absence epilepsy models. The Journal of Physiology. PMID 28901011 DOI: 10.1113/Jp274696  1
2017 Lam AD, Deck G, Goldman A, Eskandar EN, Noebels J, Cole AJ. Silent hippocampal seizures and spikes identified by foramen ovale electrodes in Alzheimer's disease. Nature Medicine. PMID 28459436 DOI: 10.1038/Nm.4330  1
2017 John Lin CC, Yu K, Hatcher A, Huang TW, Lee HK, Carlson J, Weston MC, Chen F, Zhang Y, Zhu W, Mohila CA, Ahmed N, Patel AJ, Arenkiel BR, Noebels JL, et al. Identification of diverse astrocyte populations and their malignant analogs. Nature Neuroscience. PMID 28166219 DOI: 10.1038/Nn.4493  1
2017 Tang M, Gao G, Rueda CB, Yu H, Thibodeaux DN, Awano T, Engelstad KM, Sanchez-Quintero MJ, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, Seo R, ... ... Noebels JL, et al. Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein. Nature Communications. 8: 14152. PMID 28106060 DOI: 10.1038/Ncomms14152  1
2016 Lopez AY, Wang X, Xu M, Maheshwari A, Curry D, Lam S, Adesina AM, Noebels JL, Sun QQ, Cooper EC. Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder. Molecular Psychiatry. PMID 27956739 DOI: 10.1038/Mp.2016.233  1
2016 Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Correction: Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0167264. PMID 27870904 DOI: 10.1371/journal.pone.0167264  1
2016 Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0162883. PMID 27622563 DOI: 10.1371/Journal.Pone.0162883  1
2016 Aiba I, Wehrens XH, Noebels JL. Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482086 DOI: 10.1073/Pnas.1605216113  1
2016 Holmes GL, Noebels JL. The Epilepsy Spectrum: Targeting Future Research Challenges. Cold Spring Harbor Perspectives in Medicine. 6. PMID 27371672 DOI: 10.1101/Cshperspect.A028043  0.01
2016 Bomben VC, Aiba I, Qian J, Mark MD, Herlitze S, Noebels JL. Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 405-18. PMID 26758833 DOI: 10.1523/Jneurosci.2555-15.2016  1
2016 Horváth A, Szűcs A, Barcs G, Noebels JL, Kamondi A. Epileptic Seizures in Alzheimer Disease: A Review. Alzheimer Disease and Associated Disorders. PMID 26756385 DOI: 10.1097/WAD.0000000000000134  1
2015 Maheshwari A, Marks RL, Yu KM, Noebels JL. Shift in interictal relative gamma power as a novel biomarker for drug response in two mouse models of absence epilepsy. Epilepsia. PMID 26663261 DOI: 10.1111/Epi.13265  1
2015 Noebels JL. Single-Gene Determinants of Epilepsy Comorbidity. Cold Spring Harbor Perspectives in Medicine. 5. PMID 26525453 DOI: 10.1101/cshperspect.a022756  1
2015 Siehr MS, Noebels JL. Early rescue of interneuron disease trajectory in developmental epilepsies. Current Opinion in Neurobiology. 36: 82-88. PMID 26517286 DOI: 10.1016/j.conb.2015.10.007  1
2015 Lhatoo S, Noebels J, Whittemore V. Sudden unexpected death in epilepsy: Identifying risk and preventing mortality. Epilepsia. 56: 1700-6. PMID 26494436 DOI: 10.1111/Epi.13134  1
2015 Kole MJ, Qian J, Waase MP, Klassen TL, Chen TT, Augustine GJ, Noebels JL. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11433-44. PMID 26269648 DOI: 10.1523/Jneurosci.1346-15.2015  1
2015 Glasscock E, Voigt N, McCauley MD, Sun Q, Li N, Chiang DY, Zhou XB, Molina CE, Thomas D, Schmidt C, Skapura DG, Noebels JL, Dobrev D, Wehrens XH. Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Research in Cardiology. 110: 505. PMID 26162324 DOI: 10.1007/S00395-015-0505-6  1
2015 Aiba I, Noebels JL. Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models. Science Translational Medicine. 7: 282ra46. PMID 25855492 DOI: 10.1126/Scitranslmed.Aaa4050  1
2015 Noebels J. Pathway-driven discovery of epilepsy genes. Nature Neuroscience. 18: 344-50. PMID 25710836 DOI: 10.1038/Nn.3933  1
2015 Nakao A, Miki T, Shimono K, Oka H, Numata T, Kiyonaka S, Matsushita K, Ogura H, Niidome T, Noebels JL, Wakamori M, Imoto K, Mori Y. Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering. PflüGers Archiv : European Journal of Physiology. 467: 737-52. PMID 24947601 DOI: 10.1007/s00424-014-1555-6  1
2015 Kole MJ, Qian J, Waase MP, Klassen TL, Chen TT, Augustine GJ, Noebels JL. Selective loss of presynaptic potassium channel clusters at the cerebellar basket cell terminal pinceau in adam11 mutants reveals their role in ephaptic control of purkinje cell firing Journal of Neuroscience. 35: 11433-11444. DOI: 10.1523/JNEUROSCI.1346-15.2015  1
2014 Maheshwari A, Noebels JL. Monogenic models of absence epilepsy: windows into the complex balance between inhibition and excitation in thalamocortical microcircuits. Progress in Brain Research. 213: 223-52. PMID 25194492 DOI: 10.1016/B978-0-444-63326-2.00012-0  1
2014 Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, Xi Y, Reed JG, Cheng J, Pan HL, Noebels JL, Yeh ET. Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron. 83: 1159-71. PMID 25189211 DOI: 10.1016/j.neuron.2014.07.042  1
2014 Guerrini R, Noebels J. How can advances in epilepsy genetics lead to better treatments and cures? Advances in Experimental Medicine and Biology. 813: 309-17. PMID 25012387 DOI: 10.1007/978-94-017-8914-1_25  1
2014 Ozkan ED, Creson TK, Kramár EA, Rojas C, Seese RR, Babyan AH, Shi Y, Lucero R, Xu X, Noebels JL, Miller CA, Lynch G, Rumbaugh G. Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons. Neuron. 82: 1317-33. PMID 24945774 DOI: 10.1016/J.Neuron.2014.05.015  1
2014 Bomben V, Holth J, Reed J, Cramer P, Landreth G, Noebels J. Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy. Neurobiology of Aging. 35: 2091-5. PMID 24767949 DOI: 10.1016/J.Neurobiolaging.2014.03.029  1
2014 Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL. Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3826-40. PMID 24623762 DOI: 10.1523/Jneurosci.5171-13.2014  1
2014 Olivetti PR, Maheshwari A, Noebels JL. Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome. Science Translational Medicine. 6: 220ra12. PMID 24452264 DOI: 10.1126/Scitranslmed.3007231  1
2014 Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, Zhang F, Chapman K, Lupski JR, Noebels JL, Goldman AM. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia. 55: e6-12. PMID 24372310 DOI: 10.1111/Epi.12489  1
2014 Guerrini R, Noebels J. How can advances in epilepsy genetics lead to better treatments and cures? Advances in Experimental Medicine and Biology. 813: 309-317. DOI: 10.1007/978-94-17-8914-1_25  1
2013 Maheshwari A, Nahm WK, Noebels JL. Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice. Frontiers in Cellular Neuroscience. 7: 156. PMID 24065886 DOI: 10.3389/Fncel.2013.00156  1
2013 Wilcox KS, Dixon-Salazar T, Sills GJ, Ben-Menachem E, White HS, Porter RJ, Dichter MA, Moshé SL, Noebels JL, Privitera MD, Rogawski MA. Issues related to development of new antiseizure treatments. Epilepsia. 54: 24-34. PMID 23909851 DOI: 10.1111/Epi.12296  1
2013 Cole AJ, Eskandar E, Mela T, Noebels JL, Gonzalez RG, McGuone D. Case records of the Massachusetts General Hospital. Case 18-2013: a 32-year-old woman with recurrent episodes of altered consciousness. The New England Journal of Medicine. 368: 2304-12. PMID 23758236 DOI: 10.1056/NEJMcpc1215969  1
2013 Klassen TL, Drabek J, Tomson T, Sveinsson O, von Döbeln U, Noebels JL, Goldman AM. Visual automated fluorescence electrophoresis provides simultaneous quality, quantity, and molecular weight spectra for genomic DNA from archived neonatal blood spots. The Journal of Molecular Diagnostics : Jmd. 15: 283-90. PMID 23518217 DOI: 10.1016/J.Jmoldx.2013.01.003  1
2013 Maejima T, Wollenweber P, Teusner LU, Noebels JL, Herlitze S, Mark MD. Postnatal loss of P/Q-type channels confined to rhombic-lip-derived neurons alters synaptic transmission at the parallel fiber to purkinje cell synapse and replicates genomic Cacna1a mutation phenotype of ataxia and seizures in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5162-74. PMID 23516282 DOI: 10.1523/JNEUROSCI.5442-12.2013  1
2013 Chen TT, Klassen TL, Goldman AM, Marini C, Guerrini R, Noebels JL. Novel brain expression of ClC-1 chloride channels and enrichment of CLCN1 variants in epilepsy. Neurology. 80: 1078-85. PMID 23408874 DOI: 10.1212/Wnl.0B013E31828868E7  1
2013 Eom T, Zhang C, Wang H, Lay K, Fak J, Noebels JL, Darnell RB. NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Elife. 2: e00178. PMID 23359859 DOI: 10.7554/Elife.00178  1
2013 Holth JK, Bomben VC, Reed JG, Inoue T, Younkin L, Younkin SG, Pautler RG, Botas J, Noebels JL. Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1651-9. PMID 23345237 DOI: 10.1523/Jneurosci.3191-12.2013  1
2013 Lerche H, Shah M, Beck H, Noebels J, Johnston D, Vincent A. Ion channels in genetic and acquired forms of epilepsy. The Journal of Physiology. 591: 753-64. PMID 23090947 DOI: 10.1113/Jphysiol.2012.240606  1
2012 Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, Yoo J, Herre M, Okano H, Noebels JL, Darnell RB. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 75: 1067-80. PMID 22998874 DOI: 10.1016/J.Neuron.2012.07.009  1
2012 van Rheenen W, van Blitterswijk M, Huisman MH, Vlam L, van Doormaal PT, Seelen M, Medic J, Dooijes D, de Visser M, van der Kooi AJ, Raaphorst J, Schelhaas HJ, van der Pol WL, Veldink JH, van den Berg LH. Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases. Neurology. 79: 878-82. PMID 22843265 DOI: 10.1212/WNL.0b013e3182661d14  0.01
2012 Klassen TL, von Rüden EL, Drabek J, Noebels JL, Goldman AM. Comparative analytical utility of DNA derived from alternative human specimens for molecular autopsy and diagnostics. The Journal of Molecular Diagnostics : Jmd. 14: 451-7. PMID 22796560 DOI: 10.1016/J.Jmoldx.2012.04.005  1
2012 Glasscock E, Qian J, Kole MJ, Noebels JL. Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels. The Journal of Physiology. 590: 3913-26. PMID 22641786 DOI: 10.1113/Jphysiol.2012.235606  1
2012 de Curtis M, Nehlig A, Noebels J, Sankar R, Vezzani A. WONOEP XI: Workshop summary by the Scientific Organizing Committee. Epilepsia. 53: 1275-6. PMID 22578186 DOI: 10.1111/J.1528-1167.2012.03505.X  1
2012 Olivetti PR, Noebels JL. Interneuron, interrupted: molecular pathogenesis of ARX mutations and X-linked infantile spasms. Current Opinion in Neurobiology. 22: 859-65. PMID 22565167 DOI: 10.1016/j.conb.2012.04.006  1
2012 York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, et al. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metabolism. 15: 752-63. PMID 22560224 DOI: 10.1016/J.Cmet.2012.03.020  1
2012 Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M. Identification of new epilepsy treatments: issues in preclinical methodology. Epilepsia. 53: 571-82. PMID 22292566 DOI: 10.1111/J.1528-1167.2011.03391.X  1
2012 Eom T, Zhang C, Wang H, Lay K, Fak J, Noebels JL, Darnell RB. Author response: NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure Elife. DOI: 10.7554/Elife.00178.031  1
2012 Noebels JL. Gene Control of Cortical Excitability The Cortical Neuron. DOI: 10.1093/acprof:oso/9780195083309.003.0015  1
2011 Zhu PJ, Huang W, Kalikulov D, Yoo JW, Placzek AN, Stoica L, Zhou H, Bell JC, Friedlander MJ, Krnjević K, Noebels JL, Costa-Mattioli M. Suppression of PKR promotes network excitability and enhanced cognition by interferon-γ-mediated disinhibition. Cell. 147: 1384-96. PMID 22153080 DOI: 10.1016/J.Cell.2011.11.029  1
2011 McGuire AL, Oliver JM, Slashinski MJ, Graves JL, Wang T, Kelly PA, Fisher W, Lau CC, Goss J, Okcu M, Treadwell-Deering D, Goldman AM, Noebels JL, Hilsenbeck SG. To share or not to share: a randomized trial of consent for data sharing in genome research. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 13: 948-55. PMID 21785360 DOI: 10.1097/Gim.0B013E3182227589  1
2011 Ward CS, Arvide EM, Huang TW, Yoo J, Noebels JL, Neul JL. MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10359-70. PMID 21753013 DOI: 10.1523/JNEUROSCI.0057-11.2011  1
2011 Klassen T, Davis C, Goldman A, Burgess D, Chen T, Wheeler D, McPherson J, Bourquin T, Lewis L, Villasana D, Morgan M, Muzny D, Gibbs R, Noebels J. Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy. Cell. 145: 1036-48. PMID 21703448 DOI: 10.1016/J.Cell.2011.05.025  1
2011 Shim DJ, Yang L, Reed JG, Noebels JL, Chiao PJ, Zheng H. Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons. Molecular Neurodegeneration. 6: 42. PMID 21663635 DOI: 10.1186/1750-1326-6-42  1
2011 Hirsch LJ, Donner EJ, So EL, Jacobs M, Nashef L, Noebels JL, Buchhalter JR. Abbreviated report of the NIH/NINDS workshop on sudden unexpected death in epilepsy. Neurology. 76: 1932-8. PMID 21543734 DOI: 10.1212/WNL.0b013e31821de7de  1
2011 Mark MD, Maejima T, Kuckelsberg D, Yoo JW, Hyde RA, Shah V, Gutierrez D, Moreno RL, Kruse W, Noebels JL, Herlitze S. Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4311-26. PMID 21411672 DOI: 10.1523/Jneurosci.5342-10.2011  1
2011 Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, Wu T, Hamto P, Devidze N, Yu GQ, Palop JJ, Noebels JL, Mucke L. Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 700-11. PMID 21228179 DOI: 10.1523/Jneurosci.4152-10.2011  1
2011 Noebels J. A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia. 52: 39-46. PMID 21214538 DOI: 10.1111/j.1528-1167.2010.02909.x  1
2011 Qian J, Xu K, Yoo J, Chen TT, Andrews G, Noebels JL. Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 97-104. PMID 21209194 DOI: 10.1523/JNEUROSCI.5162-10.2011  1
2010 Noebels JL, Avoli M, Rogawski M, Olsen R, Delgado-Escueta AV. "Jasper's Basic Mechanisms of the Epilepsies" Workshop. Epilepsia. 51: 1-5. PMID 21208201 DOI: 10.1111/J.1528-1167.2010.02792.X  1
2010 Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 468: 263-9. PMID 21068835 DOI: 10.1038/Nature09582  1
2010 Peebles CL, Yoo J, Thwin MT, Palop JJ, Noebels JL, Finkbeiner S. Arc regulates spine morphology and maintains network stability in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 18173-8. PMID 20921410 DOI: 10.1073/Pnas.1006546107  1
2010 Jiang YH, Pan Y, Zhu L, Landa L, Yoo J, Spencer C, Lorenzo I, Brilliant M, Noebels J, Beaudet AL. Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. Plos One. 5: e12278. PMID 20808828 DOI: 10.1371/Journal.Pone.0012278  1
2010 Zhang X, Bertaso F, Yoo JW, Baumgärtel K, Clancy SM, Lee V, Cienfuegos C, Wilmot C, Avis J, Hunyh T, Daguia C, Schmedt C, Noebels J, Jegla T. Deletion of the potassium channel Kv12.2 causes hippocampal hyperexcitability and epilepsy. Nature Neuroscience. 13: 1056-8. PMID 20676103 DOI: 10.1038/Nn.2610  1
2010 Glasscock E, Yoo JW, Chen TT, Klassen TL, Noebels JL. Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5167-75. PMID 20392939 DOI: 10.1523/Jneurosci.5591-09.2010  1
2010 Ottman R, Hirose S, Jain S, Lerche H, Lopes-Cendes I, Noebels JL, Serratosa J, Zara F, Scheffer IE. Genetic testing in the epilepsies--report of the ILAE Genetics Commission. Epilepsia. 51: 655-70. PMID 20100225 DOI: 10.1111/j.1528-1167.2009.02429.x  1
2010 Noebels JL. Isolating Epilepsy Genes and Their Comorbidiites Epilepsy & Seizure. 3: 72-83. DOI: 10.3805/EANDS.3.72  0.01
2010 Noebels JL. Voltage-gated calcium channel mutations andabsence epilepsy Epilepsia. 51: 61. DOI: 10.1111/j.1528-1167.2010.02847.x  1
2010 Noebels J. [PL5]: Epilepsy as a prototype neurodevelopmental disorder International Journal of Developmental Neuroscience. 28: 640-640. DOI: 10.1016/j.ijdevneu.2010.07.007  0.01
2009 Goldman AM, Glasscock E, Yoo J, Chen TT, Klassen TL, Noebels JL. Arrhythmia in heart and brain: KCNQ1 mutations link epilepsy and sudden unexplained death. Science Translational Medicine. 1: 2ra6. PMID 20368164 DOI: 10.1126/Scitranslmed.3000289  1
2009 Price MG, Yoo JW, Burgess DL, Deng F, Hrachovy RA, Frost JD, Noebels JL. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8752-63. PMID 19587282 DOI: 10.1523/JNEUROSCI.0915-09.2009  1
2009 Ernst WL, Noebels JL. Expanded alternative splice isoform profiling of the mouse Cav3.1/alpha1G T-type calcium channel. Bmc Molecular Biology. 10: 53. PMID 19480703 DOI: 10.1186/1471-2199-10-53  1
2009 Jacobs MP, Leblanc GG, Brooks-Kayal A, Jensen FE, Lowenstein DH, Noebels JL, Spencer DD, Swann JW. Curing epilepsy: progress and future directions. Epilepsy & Behavior : E&B. 14: 438-45. PMID 19341977 DOI: 10.1016/J.Yebeh.2009.02.036  1
2009 Ernst WL, Zhang Y, Yoo JW, Ernst SJ, Noebels JL. Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1615-25. PMID 19211869 DOI: 10.1523/JNEUROSCI.2081-08.2009  1
2009 Ernst SJ, Aguilar-Bryan L, Noebels JL. Sodium channel beta1 regulatory subunit deficiency reduces pancreatic islet glucose-stimulated insulin and glucagon secretion. Endocrinology. 150: 1132-9. PMID 18988673 DOI: 10.1210/en.2008-0991  1
2009 Noebels JL. S1-01-01: Remodeling hippocampal network excitability in mouse models of Alzheimer's Alzheimer's & Dementia. 5: P69-P69. DOI: 10.1016/j.jalz.2009.05.152  0.01
2008 Shuba YM, Perez-Reyes E, Lory P, Noebels J. T-type calcium channels: from discovery to channelopathies, 25 years of research. Channels (Austin, Tex.). 2: 299-302. PMID 18769138 DOI: 10.4161/Chan.2.4.6577  1
2008 Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox KS, Leppert MF. Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. The Journal of Physiology. 586: 3405-23. PMID 18483067 DOI: 10.1113/Jphysiol.2008.154971  1
2008 Noebels JL. 2006 Merritt Putnam Symposium: mapping epileptic circuitry. Epilepsia. 49: 1-2. PMID 18304250 DOI: 10.1111/j.1528-1167.2008.01504.x  1
2008 Seal RP, Akil O, Yi E, Weber CM, Grant L, Yoo J, Clause A, Kandler K, Noebels JL, Glowatzki E, Lustig LR, Edwards RH. Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Neuron. 57: 263-75. PMID 18215623 DOI: 10.1016/J.Neuron.2007.11.032  1
2008 Glasscock E, Noebels JL. When a disease gene is not really a disease gene Future Neurology. 3: 103-106. DOI: 10.2217/14796708.3.2.103  1
2008 Roberson ED, Meilandt WJ, Yao J, Yoo J, Noebels JL, Mucke L. P1-062: Tau reduction prevents epileptiform activity in a mouse model of Alzheimer's disease: Gene expression microarray analysis Alzheimer's & Dementia. 4: T224-T224. DOI: 10.1016/j.jalz.2008.05.648  0.01
2007 Noebels JL, Sidman RL. Persistent hypersynchronization of neocortical neurons in the mocha mutant of mouse. Journal of Neurogenetics. 21: 253-6. PMID 18161587 DOI: 10.1080/01677060701695409  1
2007 Glasscock E, Qian J, Yoo JW, Noebels JL. Masking epilepsy by combining two epilepsy genes. Nature Neuroscience. 10: 1554-8. PMID 17982453 DOI: 10.1038/Nn1999  1
2007 Lopez-Santiago LF, Meadows LS, Ernst SJ, Chen C, Malhotra JD, McEwen DP, Speelman A, Noebels JL, Maier SK, Lopatin AN, Isom LL. Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. Journal of Molecular and Cellular Cardiology. 43: 636-47. PMID 17884088 DOI: 10.1016/J.Yjmcc.2007.07.062  1
2007 Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55: 697-711. PMID 17785178 DOI: 10.1016/J.Neuron.2007.07.025  1
2007 Sisodiya S, Cross JH, Blümcke I, Chadwick D, Craig J, Crino PB, Debenham P, Delanty N, Elmslie F, Gardiner M, Golden J, Goldstein D, Greenberg DA, Guerrini R, Hanna M, ... ... Noebels JL, et al. Genetics of epilepsy: epilepsy research foundation workshop report. Epileptic Disorders : International Epilepsy Journal With Videotape. 9: 194-236. PMID 17525034 DOI: 10.1684/Epd.2007.0107  1
2007 Bi W, Yan J, Shi X, Yuva-Paylor LA, Antalffy BA, Goldman A, Yoo JW, Noebels JL, Armstrong DL, Paylor R, Lupski JR. Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes. Human Molecular Genetics. 16: 1802-13. PMID 17517686 DOI: 10.1093/Hmg/Ddm128  1
2007 Noebels JL. Pharmacoresistance: From clinic to mechanism - Proceedings from the 25th Annual Merritt-Putnam Symposium American Epilepsy Society Annual Meeting December 3, 2005 Epilepsia. 48: 1-2. DOI: 10.1111/j.1528-1167.2007.00991.x  1
2007 Noebels JL. Do mice tell us more about mechanisms than men? Epileptic Disorders. 9: 213-215.  1
2006 Goldman A, Noebels J. Invited comments on the Shostak and Ottman review. Epilepsia. 47: 1750-1; author reply. PMID 17054704 DOI: 10.1111/J.1528-1167.2006.00885_5.X  1
2006 Noebels JL. The Judith Hoyer Lecture: genes, pixels, patterns, and prevention. Epilepsy & Behavior : E&B. 9: 379-85. PMID 17029973 DOI: 10.1016/j.yebeh.2006.08.018  1
2006 Qian J, Noebels JL. Exocytosis of vesicular zinc reveals persistent depression of neurotransmitter release during metabotropic glutamate receptor long-term depression at the hippocampal CA3-CA1 synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6089-95. PMID 16738253 DOI: 10.1523/JNEUROSCI.0475-06.2006  1
2006 Goldman AM, Potocki L, Walz K, Lynch JK, Glaze DG, Lupski JR, Noebels JL. Epilepsy and chromosomal rearrangements in Smith-Magenis Syndrome [del(17)(p11.2p11.2)]. Journal of Child Neurology. 21: 93-8. PMID 16566870 DOI: 10.1177/08830738060210021201  1
2006 Wang D, Pascual JM, Yang H, Engelstad K, Mao X, Cheng J, Yoo J, Noebels JL, De Vivo DC. A mouse model for Glut-1 haploinsufficiency. Human Molecular Genetics. 15: 1169-79. PMID 16497725 DOI: 10.1093/hmg/ddl032  1
2006 Noebels J. GENES AND CHANNELS Neuropediatrics. 37. DOI: 10.1055/s-2006-945769  0.01
2006 Noebels JL. Spontaneous Epileptic Mutations in the Mouse Models of Seizures and Epilepsy. 223-232. DOI: 10.1016/B978-012088554-1/50019-0  1
2005 Brenner R, Chen QH, Vilaythong A, Toney GM, Noebels JL, Aldrich RW. BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nature Neuroscience. 8: 1752-9. PMID 16261134 DOI: 10.1038/Nn1573  1
2005 Noebels JL. Calcium channel "gaiting" and absence epilepsy. Epilepsy Currents / American Epilepsy Society. 5: 95-7. PMID 16145613 DOI: 10.1111/j.1535-7511.2005.05306.x  0.01
2005 Cobos I, Calcagnotto ME, Vilaythong AJ, Thwin MT, Noebels JL, Baraban SC, Rubenstein JL. Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy. Nature Neuroscience. 8: 1059-68. PMID 16007083 DOI: 10.1038/nn1499  1
2005 Qian J, Noebels JL. Visualization of transmitter release with zinc fluorescence detection at the mouse hippocampal mossy fibre synapse. The Journal of Physiology. 566: 747-58. PMID 15919713 DOI: 10.1113/jphysiol.2005.089276  1
2005 Senechal KR, Thaller C, Noebels JL. ADPEAF mutations reduce levels of secreted LGI1, a putative tumor suppressor protein linked to epilepsy. Human Molecular Genetics. 14: 1613-20. PMID 15857855 DOI: 10.1093/hmg/ddi169  1
2005 Jankovic J, Noebels JL. Genetic mouse models of essential tremor: are they essential? The Journal of Clinical Investigation. 115: 584-6. PMID 15765140 DOI: 10.1172/JCI24544  1
2005 Noebels JL. The developing epileptic brain Epilepsia. 46: 5-6. DOI: 10.1111/j.1528-1167.2005.00307.x  1
2004 May P, Rohlmann A, Bock HH, Zurhove K, Marth JD, Schomburg ED, Noebels JL, Beffert U, Sweatt JD, Weeber EJ, Herz J. Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Molecular and Cellular Biology. 24: 8872-83. PMID 15456862 DOI: 10.1128/Mcb.24.20.8872-8883.2004  1
2004 Collins AL, Levenson JM, Vilaythong AP, Richman R, Armstrong DL, Noebels JL, David Sweatt J, Zoghbi HY. Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Human Molecular Genetics. 13: 2679-89. PMID 15351775 DOI: 10.1093/Hmg/Ddh282  1
2004 Mori M, Burgess DL, Gefrides LA, Foreman PJ, Opferman JT, Korsmeyer SJ, Cavalheiro EA, Naffah-Mazzacoratti MG, Noebels JL. Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death and Differentiation. 11: 1223-33. PMID 15286683 DOI: 10.1038/Sj.Cdd.4401483  1
2004 Zhang Y, Vilaythong AP, Yoshor D, Noebels JL. Elevated thalamic low-voltage-activated currents precede the onset of absence epilepsy in the SNAP25-deficient mouse mutant coloboma. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5239-48. PMID 15175394 DOI: 10.1523/Jneurosci.0992-04.2004  1
2004 Chen C, Westenbroek RE, Xu X, Edwards CA, Sorenson DR, Chen Y, McEwen DP, O'Malley HA, Bharucha V, Meadows LS, Knudsen GA, Vilaythong A, Noebels JL, Saunders TL, Scheuer T, et al. Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4030-42. PMID 15102918 DOI: 10.1523/Jneurosci.4139-03.2004  1
2003 Noebels JL. How a Sodium Channel Mutation Causes Epilepsy. Epilepsy Currents / American Epilepsy Society. 3: 70-71. PMID 15309091 DOI: 10.1046/j.1535-7597.2003.03214.x  0.01
2003 Noebels JL. Stiff Goats, Chloride Ions, and Idiopathic Generalized Epilepsy (IGE). Epilepsy Currents / American Epilepsy Society. 3: 146-147. PMID 15309062 DOI: 10.1046/j.1535-7597.2003.03414.x  0.01
2003 Noebels JL. The biology of epilepsy genes. Annual Review of Neuroscience. 26: 599-625. PMID 14527270 DOI: 10.1146/annurev.neuro.26.010302.081210  1
2003 Qian J, Noebels JL. Topiramate alters excitatory synaptic transmission in mouse hippocampus. Epilepsy Research. 55: 225-33. PMID 12972176 DOI: 10.1016/S0920-1211(03)00120-7  1
2003 Houseweart MK, Vilaythong A, Yin XM, Turk B, Noebels JL, Myers RM. Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death and Differentiation. 10: 1329-35. PMID 12934064 DOI: 10.1038/sj.cdd.4401309  1
2003 Houseweart MK, Pennacchio LA, Vilaythong A, Peters C, Noebels JL, Myers RM. Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1). Journal of Neurobiology. 56: 315-27. PMID 12918016 DOI: 10.1002/Neu.10253  1
2003 Noebels JL. Exploring new gene discoveries in idiopathic generalized epilepsy. Epilepsia. 44: 16-21. PMID 12752457 DOI: 10.1046/J.1528-1157.44.S.2.4.X  1
2003 Walz K, Caratini-Rivera S, Bi W, Fonseca P, Mansouri DL, Lynch J, Vogel H, Noebels JL, Bradley A, Lupski JR. Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Molecular and Cellular Biology. 23: 3646-55. PMID 12724422 DOI: 10.1128/Mcb.23.10.3646-3655.2003  1
2003 Kantheti P, Diaz ME, Peden AE, Seong EE, Dolan DF, Robinson MS, Noebels JL, Burmeister ML. Genetic and phenotypic analysis of the mouse mutant mh2J, an Ap3d allele caused by IAP element insertion. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 157-67. PMID 12647238 DOI: 10.1007/s00335-002-2238-8  1
2003 Powell EM, Campbell DB, Stanwood GD, Davis C, Noebels JL, Levitt P. Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 622-31. PMID 12533622  1
2003 Powell EM, Campbell DB, Stanwood GD, Davis C, Noebels JL, Levitt P. Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction. The Journal of Neuroscience. 23: 622-631. DOI: 10.1523/Jneurosci.23-02-00622.2003  1
2002 Noebels JL. Human Epilepsy Can Be Linked to a Defective Calcium Channel. Epilepsy Currents / American Epilepsy Society. 2: 95. PMID 15309155 DOI: 10.1046/j.1535-7597.2002.t01-1-00034.x  0.01
2002 Noebels JL. A Gene for JME at Last: The alpha1 GABA Receptor Subunit. Epilepsy Currents / American Epilepsy Society. 2: 131-132. PMID 15309143 DOI: 10.1046/j.1535-7597.2002.t01-1-00050.x  0.01
2002 Stables JP, Bertram EH, White HS, Coulter DA, Dichter MA, Jacobs MP, Loscher W, Lowenstein DH, Moshe SL, Noebels JL, Davis M. Models for epilepsy and epileptogenesis: report from the NIH workshop, Bethesda, Maryland. Epilepsia. 43: 1410-20. PMID 12423393 DOI: 10.1046/J.1528-1157.2002.06702.X  1
2002 Anderson E, Berkovic S, Dulac O, Gardiner M, Jain S, Laue Friis M, Lindhout D, Noebels J, Ottman R, Scaramelli A, Serratosa J, Steinlein O, Avanzini G, Bailey-Wilson J, Cardon L, et al. ILAE genetics commission conference report: molecular analysis of complex genetic epilepsies. Epilepsia. 43: 1262-7. PMID 12366744 DOI: 10.1046/J.1528-1157.2002.29502.X  1
2002 Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J, Armstrong D, Paylor R, Zoghbi H. Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron. 35: 243-54. PMID 12160743 DOI: 10.1016/S0896-6273(02)00768-7  1
2002 Zhang Y, Mori M, Burgess DL, Noebels JL. Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6362-71. PMID 12151514 DOI: 10.1523/Jneurosci.22-15-06362.2002  1
2002 Poolos NP, Das S, Clark GD, Lardizabal D, Noebels JL, Wyllie E, Dobyns WB. Males with epilepsy, complete subcortical band heterotopia, and somatic mosaicism for DCX. Neurology. 58: 1559-62. PMID 12034802 DOI: 10.1212/Wnl.58.10.1559  1
2002 Noebels JL. Sodium channel gene expression and epilepsy. Novartis Foundation Symposium. 241: 109-20; discussion 1. PMID 11771641 DOI: 10.1002/0470846682.Ch8  1
2002 Zhang Y, Mori M, Burgess DL, Noebels JL. Mutations in High-Voltage-Activated Calcium Channel Genes Stimulate Low-Voltage-Activated Currents in Mouse Thalamic Relay Neurons The Journal of Neuroscience. 22: 6362-6371. DOI: 10.1523/JNEUROSCI.22-15-06362.2002  0.01
2001 Noebels JL. Modeling human epilepsies in mice. Epilepsia. 42: 11-5. PMID 11887961 DOI: 10.1046/j.1528-1157.2001.0420s5011.x  1
2001 Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, Morrell MJ, Noebels JL, Rogawski MA, Spencer SS, Theodore WH. Future directions for epilepsy research. Neurology. 57: 1536-42. PMID 11706087 DOI: 10.1212/Wnl.57.9.1536  1
2001 Heilstedt HA, Burgess DL, Anderson AE, Chedrawi A, Tharp B, Lee O, Kashork CD, Starkey DE, Wu YQ, Noebels JL, Shaffer LG, Shapira SK. Loss of the potassium channel beta-subunit gene, KCNAB2, is associated with epilepsy in patients with 1p36 deletion syndrome. Epilepsia. 42: 1103-11. PMID 11580756 DOI: 10.1046/J.1528-1157.2001.08801.X  1
2001 Qian J, Noebels JL. Presynaptic Ca2+ channels and neurotransmitter release at the terminal of a mouse cortical neuron. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3721-8. PMID 11356859 DOI: 10.1523/Jneurosci.21-11-03721.2001  1
2001 Qiao X, Suri C, Knusel B, Noebels JL. Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain-derived neurotrophic factor. Journal of Neuroscience Research. 64: 268-76. PMID 11319771 DOI: 10.1002/jnr.1075  1
2001 Burgess DL, Gefrides LA, Foreman PJ, Noebels JL. A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. Genomics. 71: 339-50. PMID 11170751 DOI: 10.1006/geno.2000.6440  1
2001 Zwingman TA, Neumann PE, Noebels JL, Herrup K. Rocker is a new variant of the voltage-dependent calcium channel gene Cacna1a. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1169-78. PMID 11160387 DOI: 10.1523/Jneurosci.21-04-01169.2001  1
2000 Lau D, Vega-Saenz de Miera EC, Contreras D, Ozaita A, Harvey M, Chow A, Noebels JL, Paylor R, Morgan JI, Leonard CS, Rudy B. Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9071-85. PMID 11124984 DOI: 10.1523/Jneurosci.20-24-09071.2000  1
2000 Matsuura T, Yamagata T, Burgess DL, Rasmussen A, Grewal RP, Watase K, Khajavi M, McCall AE, Davis CF, Zu L, Achari M, Pulst SM, Alonso E, Noebels JL, Nelson DL, et al. Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10. Nature Genetics. 26: 191-4. PMID 11017075 DOI: 10.1038/79911  1
2000 Burgess DL, Noebels JL. Calcium channel defects in models of inherited generalized epilepsy. Epilepsia. 41: 1074-5. PMID 10961647 DOI: 10.1111/J.1528-1157.2000.Tb00305.X  1
2000 Kellaway P, Mizrahi EM, Noebels JL. Benign focal epilepsies of childhood: genetically determined pathophysiology. Report of an international workshop. Epilepsia. 41: 1049-50. PMID 10961636 DOI: 10.1111/J.1528-1157.2000.TB00294.X  1
2000 Steinlein OK, Noebels JL. Ion channels and epilepsy in man and mouse. Current Opinion in Genetics & Development. 10: 286-91. PMID 10826987 DOI: 10.1016/S0959-437X(00)00079-4  1
2000 Ayata C, Shimizu-Sasamata M, Lo EH, Noebels JL, Moskowitz MA. Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the alpha1A subunit of P/Q type calcium channels. Neuroscience. 95: 639-45. PMID 10670432 DOI: 10.1016/S0306-4522(99)00446-7  1
2000 Burgess DL, Matsuura T, Ashizawa T, Noebels JL. Genetic localization of the Ca2+ channel gene CACNG2 near SCA10 on chromosome 22q13. Epilepsia. 41: 24-7. PMID 10643919 DOI: 10.1111/J.1528-1157.2000.Tb01500.X  1
2000 Liu M, Pleasure SJ, Collins AE, Noebels JL, Naya FJ, Tsai MJ, Lowenstein DH. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proceedings of the National Academy of Sciences of the United States of America. 97: 865-70. PMID 10639171 DOI: 10.1073/pnas.97.2.865  1
2000 Qian J, Noebels JL. Presynaptic Ca(2+) influx at a mouse central synapse with Ca(2+) channel subunit mutations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 163-70. PMID 10627593  1
2000 Qian J, Noebels JL. Presynaptic Ca2+ Influx at a Mouse Central Synapse with Ca2+ Channel Subunit Mutations The Journal of Neuroscience. 20: 163-170. DOI: 10.1523/Jneurosci.20-01-00163.2000  1
2000 Noebels JL, Burgess DL, Qian J. Nature in the development of epilepsy Acta Neurologica Scandinavica, Supplement. 102: 11-13. DOI: 10.1034/J.1600-0404.2000.00202-6.X  1
1999 Burgess DL, Davis CF, Gefrides LA, Noebels JL. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Research. 9: 1204-13. PMID 10613843 DOI: 10.1101/gr.9.12.1204  1
1999 Burgess DL, Noebels JL. Single gene defects in mice: the role of voltage-dependent calcium channels in absence models. Epilepsy Research. 36: 111-22. PMID 10515159 DOI: 10.1016/S0920-1211(99)00045-5  1
1999 Noebels JL. Single-gene models of epilepsy. Advances in Neurology. 79: 227-38. PMID 10514817  1
1999 Burgess DL, Noebels JL. Voltage-dependent calcium channel mutations in neurological disease. Annals of the New York Academy of Sciences. 868: 199-212. PMID 10414295 DOI: 10.1111/j.1749-6632.1999.tb11287.x  1
1999 Hartmann HA, Colom LV, Sutherland ML, Noebels JL. Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain. Nature Neuroscience. 2: 593-5. PMID 10404176 DOI: 10.1038/10147  1
1999 Burgess DL, Biddlecome GH, McDonough SI, Diaz ME, Zilinski CA, Bean BP, Campbell KP, Noebels JL. beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain. Molecular and Cellular Neurosciences. 13: 293-311. PMID 10328888 DOI: 10.1006/Mcne.1999.0748  1
1999 Sutherland ML, Williams SH, Abedi R, Overbeek PA, Pfaffinger PJ, Noebels JL. Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proceedings of the National Academy of Sciences of the United States of America. 96: 2451-5. PMID 10051663 DOI: 10.1073/pnas.96.5.2451  1
1999 Clark GD, Noebels JL. Cortin disaster: lissencephaly genes spell double trouble for the developing brain. Annals of Neurology. 45: 141-2. PMID 9989613 DOI: 10.1002/1531-8249(199902)45:2<141::AID-ANA1>3.0.CO;2-7  1
1999 Noebels JL, Hartmann H, Sutherland ML, Colom LV. A novel candidate sodium channel gene for ljmbic epilepsy Italian Journal of Neurological Sciences. 20: 200.  1
1998 Noebels JL. Ion Channelopathies and Heritable Epilepsy. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 13: 255-256. PMID 11390799 DOI: 10.1152/Physiologyonline.1998.13.5.255  1
1998 Jiang YH, Armstrong D, Albrecht U, Atkins CM, Noebels JL, Eichele G, Sweatt JD, Beaudet AL. Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron. 21: 799-811. PMID 9808466 DOI: 10.1016/S0896-6273(00)80596-6  1
1998 Pennacchio LA, Bouley DM, Higgins KM, Scott MP, Noebels JL, Myers RM. Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice. Nature Genetics. 20: 251-8. PMID 9806543 DOI: 10.1038/3059  1
1998 Nahm WK, Noebels JL. Nonobligate role of early or sustained expression of immediate-early gene proteins c-fos, c-jun, and Zif/268 in hippocampal mossy fiber sprouting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9245-55. PMID 9801364 DOI: 10.1523/Jneurosci.18-22-09245.1998  1
1998 Kantheti P, Qiao X, Diaz ME, Peden AA, Meyer GE, Carskadon SL, Kapfhamer D, Sufalko D, Robinson MS, Noebels JL, Burmeister M. Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron. 21: 111-22. PMID 9697856 DOI: 10.1016/S0896-6273(00)80519-X  1
1998 Westenbroek RE, Bausch SB, Lin RC, Franck JE, Noebels JL, Catterall WA. Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2321-34. PMID 9502793 DOI: 10.1523/Jneurosci.18-07-02321.1998  1
1997 Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14060-5. PMID 9391152 DOI: 10.1073/Pnas.94.25.14060  1
1997 Cox GA, Lutz CM, Yang CL, Biemesderfer D, Bronson RT, Fu A, Aronson PS, Noebels JL, Frankel WN. Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell. 91: 139-48. PMID 9335342 DOI: 10.1016/S0092-8674(01)80016-7  1
1997 Cattanach BM, Barr JA, Beechey CV, Martin J, Noebels J, Jones J. A candidate model for Angelman syndrome in the mouse. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 472-8. PMID 9195990 DOI: 10.1007/S003359900479  1
1997 Di Pasquale E, Keegan KD, Noebels JL. Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer. Journal of Neurophysiology. 77: 621-31. PMID 9065835 DOI: 10.1152/Jn.1997.77.2.621  1
1997 Burgess DL, Jones JM, Meisler MH, Noebels JL. Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell. 88: 385-92. PMID 9039265 DOI: 10.1016/S0092-8674(00)81877-2  1
1997 Noebels JL, Qiao X, Nahm WK. Neurogenetic approaches to axon sprouting in the hippocampus. Advances in Neurology. 72: 35-44. PMID 8993682  1
1996 Noebels JL, Sutherland ML, Nahm WK, DiPasquale E. Molecular and cellular plasticity in developing epileptic brain. Cold Spring Harbor Symposia On Quantitative Biology. 61: 319-26. PMID 9246461 DOI: 10.1101/Sqb.1996.061.01.035  1
1996 Noebels JL. Targeting epilepsy genes. Neuron. 16: 241-4. PMID 8789939 DOI: 10.1016/S0896-6273(00)80042-2  1
1996 Sutherland ML, Delaney TA, Noebels JL. Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2191-207. PMID 8601800 DOI: 10.1523/Jneurosci.16-07-02191.1996  1
1996 Qiao X, Hefti F, Knusel B, Noebels JL. Selective failure of brain-derived neurotrophic factor mRNA expression in the cerebellum of stargazer, a mutant mouse with ataxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 640-8. PMID 8551348 DOI: 10.1523/Jneurosci.16-02-00640.1996  1
1995 Wang H, Allen ML, Grigg JJ, Noebels JL, Tempel BL. Hypomyelination alters K+ channel expression in mouse mutants shiverer and Trembler. Neuron. 15: 1337-47. PMID 8845157 DOI: 10.1016/0896-6273(95)90012-8  1
1995 Noebels JL. Single locus mutations in mice expressing generalized spike-wave absence epilepsies. Italian Journal of Neurological Sciences. 16: 107-11. PMID 7642343 DOI: 10.1007/BF02229082  1
1995 Sutherland ML, Delaney TA, Noebels JL. Molecular characterization of a high-affinity mouse glutamate transporter. Gene. 162: 271-4. PMID 7557442 DOI: 10.1016/0378-1119(95)00293-F  1
1995 Chafetz RS, Nahm WK, Noebels JL. Aberrant expression of neuropeptide Y in hippocampal mossy fibers in the absence of local cell injury following the onset of spike-wave synchronization. Brain Research. Molecular Brain Research. 31: 111-21. PMID 7476019 DOI: 10.1016/0169-328X(95)00041-P  1
1994 Helekar SA, Noebels JL. Analysis of voltage-gated and synaptic conductances contributing to network excitability defects in the mutant mouse tottering. Journal of Neurophysiology. 71: 1-10. PMID 8158221 DOI: 10.1152/Jn.1994.71.1.1  1
1994 Frankel WN, Taylor BA, Noebels JL, Lutz CM. Genetic epilepsy model derived from common inbred mouse strains. Genetics. 138: 481-9. PMID 7828829  1
1993 Buckwalter MS, Testa CM, Noebels JL, Camper SA. Genetic mapping and evaluation of candidate genes for spasmodic, a neurological mouse mutation with abnormal startle response. Genomics. 17: 279-86. PMID 8406478 DOI: 10.1006/geno.1993.1322  1
1993 Wu SM, Qiao X, Noebels JL, Yang XL. Localization and modulatory actions of zinc in vertebrate retina. Vision Research. 33: 2611-6. PMID 8296456 DOI: 10.1016/0042-6989(93)90219-M  1
1993 Qiao X, Noebels JL. Developmental analysis of hippocampal mossy fiber outgrowth in a mutant mouse with inherited spike-wave seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4622-35. PMID 8229188 DOI: 10.1523/Jneurosci.13-11-04622.1993  1
1992 Helekar SA, Noebels JL. A burst-dependent hippocampal excitability defect elicited by potassium at the developmental onset of spike-wave seizures in the Tottering mutant. Brain Research. Developmental Brain Research. 65: 205-10. PMID 1572065 DOI: 10.1016/0165-3806(92)90180-5  1
1992 Westenbroek RE, Noebels JL, Catterall WA. Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 2259-67. PMID 1318958 DOI: 10.1523/Jneurosci.12-06-02259.1992  1
1991 Helekar SA, Noebels JL. Synchronous hippocampal bursting reveals network excitability defects in an epilepsy gene mutation. Proceedings of the National Academy of Sciences of the United States of America. 88: 4736-40. PMID 2052555 DOI: 10.1073/Pnas.88.11.4736  1
1991 Qiao XX, Noebels JL. Genetic and phenotypic heterogeneity of inherited spike-wave epilepsy: two mutant gene loci with independent cerebral excitability defects. Brain Research. 555: 43-50. PMID 1933329 DOI: 10.1016/0006-8993(91)90857-R  1
1991 Noebels JL. Mutational analysis of spike-wave epilepsy phenotypes. Epilepsy Research. Supplement. 4: 201-12. PMID 1815603  1
1991 Noebels JL, Marcom PK, Jalilian-Tehrani MH. Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion. Nature. 352: 431-4. PMID 1713650 DOI: 10.1038/352431a0  1
1990 Noebels JL, Rutecki PA. Altered hippocampal network excitability in the hypernoradrenergic mutant mouse tottering. Brain Research. 524: 225-30. PMID 2292005 DOI: 10.1016/0006-8993(90)90695-8  1
1990 Noebels JL, Qiao X, Bronson RT, Spencer C, Davisson MT. Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures. Epilepsy Research. 7: 129-35. PMID 2289471 DOI: 10.1016/0920-1211(90)90098-G  1
1989 Noebels JL, Sidman RL. Persistent hypersynchronization of neocortical neurons in the mocha mutant of mouse. Journal of Neurogenetics. 6: 53-6. PMID 2778559 DOI: 10.3109/01677068909107100  1
1986 Noebels JL. Mutational analysis of inherited epilepsies. Advances in Neurology. 44: 97-113. PMID 2871726  1
1985 Noebels JL. Tracing the cellular expression of neuromodulatory genes Trends in Neurosciences. 8: 327-331. DOI: 10.1016/0166-2236(85)90114-6  1
1984 Noebels JL. A single gene error of noradrenergic axon growth synchronizes central neurones. Nature. 310: 409-11. PMID 6462226 DOI: 10.1038/310409a0  1
1984 Noebels JL. Isolating single genes of the inherited epilepsies. Annals of Neurology. 16: S18-21. PMID 6095738 DOI: 10.1002/Ana.410160705  1
1981 Levitt P, Noebels JL. Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation. Proceedings of the National Academy of Sciences of the United States of America. 78: 4630-4. PMID 6945603 DOI: 10.1073/Pnas.78.7.4630  1
1981 Heller AH, Dichter MA, Noebels JL, Sidman RL. Anticonvulsant effects on spike-wave seizures in the mutant mouse tottering: A new genetic model of spike-wave epilepsy Epilepsia. 22: 227-228.  1
1979 Noebels JL, Sidman RL. Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering. Science (New York, N.Y.). 204: 1334-6. PMID 572084 DOI: 10.1126/Science.572084  1
1979 Noebels JL. Analysis of inherited epilepsy using single locus mutations in mice. Federation Proceedings. 38: 2405-10. PMID 383515  1
1978 Noebels JL, Prince DA. Development of focal seizures in cerebral cortex: role of axon terminal bursting. Journal of Neurophysiology. 41: 1267-81. PMID 702194 DOI: 10.1152/Jn.1978.41.5.1267  1
1978 Noebels JL, Roth WT, Kopell BS. Cortical slow potentials and the occipital EEG in congenital blindness. Journal of the Neurological Sciences. 37: 51-8. PMID 690664 DOI: 10.1016/0022-510X(78)90227-7  1
1978 Noebels JL, Prince DA. Excitability changes in thalamocortical relay neurons during synchronous discharges in cat neocortex. Journal of Neurophysiology. 41: 1282-96. PMID 212538 DOI: 10.1152/Jn.1978.41.5.1282  1
1977 Noebels JL, Pedley TA. Anatomic localization of topically applied [14C]penicillin during experimental focal epilepsy in cat neocortex. Brain Research. 125: 293-303. PMID 404001 DOI: 10.1016/0006-8993(77)90622-9  1
1977 Noebels JL, Prince DA. Presynaptic origin of penicillin after discharges at mammalian nerve terminals. Brain Research. 138: 59-74. PMID 201346 DOI: 10.1016/0006-8993(77)90784-3  1
1975 Schwartzkroin PA, Futamachi KJ, Noebels JL, Prince DA. Transcallosal effects of a cortical epileptiform focus. Brain Research. 99: 59-68. PMID 1188986 DOI: 10.1016/0006-8993(75)90608-3  1
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