Tomas Kirchhausen - Publications

Affiliations: 
Cell Biology Harvard Medical School, Boston, MA, United States 
Area:
Immune Disease
Website:
http://www.fas.harvard.edu/~biophys/Tomas_Kirchhausen.htm

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Year Citation  Score
2018 Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, ... ... Kirchhausen T, et al. The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Reports. 24: 973-986.e8. PMID 30044992 DOI: 10.1016/J.Celrep.2018.06.100  0.332
2017 Raaben M, Jae LT, Herbert AS, Kuehne AI, Stubbs SH, Chou YY, Blomen VA, Kirchhausen T, Dye JM, Brummelkamp TR, Whelan SP. NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry. Cell Host & Microbe. 22: 688-696.e5. PMID 29120745 DOI: 10.1016/J.Chom.2017.10.002  0.349
2017 Adell MAY, Migliano SM, Upadhyayula S, Bykov YS, Sprenger S, Pakdel M, Vogel GF, Jih G, Skillern W, Behrouzi R, Babst M, Schmidt O, Hess MW, Briggs JA, Kirchhausen T, et al. Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding. Elife. 6. PMID 29019322 DOI: 10.7554/Elife.31652  0.371
2017 Adell MAY, Migliano SM, Upadhyayula S, Bykov YS, Sprenger S, Pakdel M, Vogel GF, Jih G, Skillern W, Behrouzi R, Babst M, Schmidt O, Hess MW, Briggs JA, Kirchhausen T, et al. Author response: Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding Elife. DOI: 10.7554/Elife.31652.037  0.3
2016 Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Kirchhausen T, et al. Seipin is required for converting nascent to mature lipid droplets. Elife. 5. PMID 27564575 DOI: 10.7554/Elife.16582  0.31
2016 Aguet F, Upadhyayula S, Gaudin R, Chou YY, Cocucci E, He K, Chen BC, Mosaliganti K, Pasham M, Skillern W, Legant WR, Liu TL, Findlay G, Marino E, Danuser G, ... ... Kirchhausen T, et al. Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy. Molecular Biology of the Cell. PMID 27535432 DOI: 10.1091/Mbc.E16-03-0164  0.678
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Kirchhausen T, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882  0.737
2015 Li D, Shao L, Chen BC, Zhang X, Zhang M, Moses B, Milkie DE, Beach JR, Hammer JA, Pasham M, Kirchhausen T, Baird MA, Davidson MW, Xu P, Betzig E. ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics. Science (New York, N.Y.). 349: aab3500. PMID 26315442 DOI: 10.1126/Science.Aab3500  0.312
2015 Kural C, Akatay AA, Gaudin R, Chen BC, Legant WR, Betzig E, Kirchhausen T. Asymmetric formation of coated pits on dorsal and ventral surfaces at the leading edges of motile cells and on protrusions of immobile cells. Molecular Biology of the Cell. 26: 2044-53. PMID 25851602 DOI: 10.1091/Mbc.E15-01-0055  0.334
2014 Cocucci E, Gaudin R, Kirchhausen T. Dynamin recruitment and membrane scission at the neck of a clathrin-coated pit. Molecular Biology of the Cell. 25: 3595-609. PMID 25232009 DOI: 10.1091/Mbc.E14-07-1240  0.727
2014 Abdelhakim AH, Salgado EN, Fu X, Pasham M, Nicastro D, Kirchhausen T, Harrison SC. Structural correlates of rotavirus cell entry. Plos Pathogens. 10: e1004355. PMID 25211455 DOI: 10.1371/Journal.Ppat.1004355  0.522
2014 Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S. In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos. Journal of Cell Science. 127: 3970-82. PMID 25074807 DOI: 10.1242/Dev.117259  0.334
2014 Böcking T, Aguet F, Rapoport I, Banzhaf M, Yu A, Zeeh JC, Kirchhausen T. Key interactions for clathrin coat stability. Structure (London, England : 1993). 22: 819-29. PMID 24815030 DOI: 10.1016/j.str.2014.04.002  0.31
2014 Kirchhausen T, Owen D, Harrison SC. Molecular structure, function, and dynamics of clathrin-mediated membrane traffic. Cold Spring Harbor Perspectives in Biology. 6: a016725. PMID 24789820 DOI: 10.1101/Cshperspect.A016725  0.54
2014 Kural C, Boulant S, Kirchhausen T. Dynamics of Intracellular Clathrin Carriers Biophysical Journal. 106: 310a. DOI: 10.1016/J.Bpj.2013.11.1794  0.432
2013 Piccinotti S, Kirchhausen T, Whelan SP. Uptake of rabies virus into epithelial cells by clathrin-mediated endocytosis depends upon actin. Journal of Virology. 87: 11637-47. PMID 23966407 DOI: 10.1128/Jvi.01648-13  0.376
2013 Heesters BA, Chatterjee P, Kim YA, Gonzalez SF, Kuligowski MP, Kirchhausen T, Carroll MC. Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation. Immunity. 38: 1164-75. PMID 23770227 DOI: 10.1016/J.Immuni.2013.02.023  0.307
2013 Boulant S, Stanifer M, Kural C, Cureton DK, Massol R, Nibert ML, Kirchhausen T. Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin-Darby canine kidney cells. Molecular Biology of the Cell. 24: 1196-207. PMID 23427267 DOI: 10.1091/Mbc.E12-12-0852  0.349
2013 Ishikawa Y, Tacheva-Grigorova SK, Maeda M, Aguet F, Lee S, Ericsson M, Kirchhausen T, Maeda T. Cellular Mechanisms For Transferrin Receptor Endocytosis Vital For Terminal Erythroid Differentiation Blood. 122: 3434-3434. DOI: 10.1182/Blood.V122.21.3434.3434  0.401
2012 Kural C, Tacheva-Grigorova SK, Boulant S, Cocucci E, Baust T, Duarte D, Kirchhausen T. Dynamics of intracellular clathrin/AP1- and clathrin/AP3-containing carriers. Cell Reports. 2: 1111-9. PMID 23103167 DOI: 10.1016/J.Celrep.2012.09.025  0.688
2012 Cocucci E, Aguet F, Boulant S, Kirchhausen T. The first five seconds in the life of a clathrin-coated pit. Cell. 150: 495-507. PMID 22863004 DOI: 10.1016/J.Cell.2012.05.047  0.713
2012 Lu L, Kirchhausen T. Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane. Communicative & Integrative Biology. 5: 16-8. PMID 22482003 DOI: 10.4161/Cib.18308  0.34
2012 Cureton DK, Harbison CE, Cocucci E, Parrish CR, Kirchhausen T. Limited transferrin receptor clustering allows rapid diffusion of canine parvovirus into clathrin endocytic structures. Journal of Virology. 86: 5330-40. PMID 22357278 DOI: 10.1128/Jvi.07194-11  0.714
2011 Boulant S, Kural C, Zeeh JC, Ubelmann F, Kirchhausen T. Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nature Cell Biology. 13: 1124-31. PMID 21841790 DOI: 10.1038/Ncb2307  0.416
2011 Ivanovic T, Boulant S, Ehrlich M, Demidenko AA, Arnold MM, Kirchhausen T, Nibert ML. Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking. Traffic (Copenhagen, Denmark). 12: 1179-95. PMID 21736684 DOI: 10.1111/J.1600-0854.2011.01233.X  0.388
2011 Thiery J, Keefe D, Boulant S, Boucrot E, Walch M, Martinvalet D, Goping IS, Bleackley RC, Kirchhausen T, Lieberman J. Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nature Immunology. 12: 770-7. PMID 21685908 DOI: 10.1038/Ni.2050  0.345
2011 Boucrot E, Howes MT, Kirchhausen T, Parton RG. Redistribution of caveolae during mitosis. Journal of Cell Science. 124: 1965-72. PMID 21625007 DOI: 10.1242/Jcs.076570  0.362
2011 Bai M, Gad H, Turacchio G, Cocucci E, Yang JS, Li J, Beznoussenko GV, Nie Z, Luo R, Fu L, Collawn JF, Kirchhausen T, Luini A, Hsu VW. ARFGAP1 promotes AP-2-dependent endocytosis. Nature Cell Biology. 13: 559-67. PMID 21499258 DOI: 10.1038/Ncb2221  0.721
2011 Böcking T, Aguet F, Harrison SC, Kirchhausen T. Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating. Nature Structural & Molecular Biology. 18: 295-301. PMID 21278753 DOI: 10.1038/Nsmb.1985  0.539
2011 Kural C, Boulant S, Kirchhausen T. Real-Time Imaging of Clathrin Dynamics in Three Dimensions Biophysical Journal. 100: 30a. DOI: 10.1016/J.Bpj.2010.12.369  0.442
2011 Kirchhausen T. Real Time Imaging of Clathrin Coat Formation with Molecular-Scale Resolution Biophysical Journal. 100: 16a. DOI: 10.1016/J.Bpj.2010.12.297  0.362
2010 Yu A, Xing Y, Harrison SC, Kirchhausen T. Structural analysis of the interaction between Dishevelled2 and clathrin AP-2 adaptor, a critical step in noncanonical Wnt signaling. Structure (London, England : 1993). 18: 1311-20. PMID 20947020 DOI: 10.1016/J.Str.2010.07.010  0.534
2010 Cureton DK, Massol RH, Whelan SP, Kirchhausen T. The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis. Plos Pathogens. 6: e1001127. PMID 20941355 DOI: 10.1371/Journal.Ppat.1001127  0.398
2010 Guan R, Dai H, Han D, Harrison SC, Kirchhausen T. Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding. Structure (London, England : 1993). 18: 1191-8. PMID 20826345 DOI: 10.1016/J.Str.2010.06.016  0.742
2010 Harrison SC, Kirchhausen T. Structural biology: Conservation in vesicle coats. Nature. 466: 1048-9. PMID 20739998 DOI: 10.1038/4661048A  0.583
2010 Utskarpen A, Massol R, van Deurs B, Lauvrak SU, Kirchhausen T, Sandvig K. Shiga toxin increases formation of clathrin-coated pits through Syk kinase. Plos One. 5: e10944. PMID 20668539 DOI: 10.1371/Journal.Pone.0010944  0.435
2010 Boucrot E, Saffarian S, Zhang R, Kirchhausen T. Roles of AP-2 in clathrin-mediated endocytosis. Plos One. 5: e10597. PMID 20485680 DOI: 10.1371/Journal.Pone.0010597  0.691
2010 Anitei M, Stange C, Parshina I, Baust T, Schenck A, Raposo G, Kirchhausen T, Hoflack B. Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nature Cell Biology. 12: 330-40. PMID 20228810 DOI: 10.1038/Ncb2034  0.458
2010 Thiery J, Keefe D, Saffarian S, Martinvalet D, Walch M, Boucrot E, Kirchhausen T, Lieberman J. Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis. Blood. 115: 1582-93. PMID 20038786 DOI: 10.1182/Blood-2009-10-246116  0.69
2010 Xing Y, Böcking T, Wolf M, Grigorieff N, Kirchhausen T, Harrison SC. Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. The Embo Journal. 29: 655-65. PMID 20033059 DOI: 10.1038/Emboj.2009.383  0.499
2009 Kirchhausen T. Imaging endocytic clathrin structures in living cells. Trends in Cell Biology. 19: 596-605. PMID 19836955 DOI: 10.1016/j.tcb.2009.09.002  0.343
2009 Saffarian S, Cocucci E, Kirchhausen T. Distinct dynamics of endocytic clathrin-coated pits and coated plaques. Plos Biology. 7: e1000191. PMID 19809571 DOI: 10.1016/J.Bpj.2008.12.3732  0.809
2009 Cureton DK, Massol RH, Saffarian S, Kirchhausen TL, Whelan SP. Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization. Plos Pathogens. 5: e1000394. PMID 19390604 DOI: 10.1371/Journal.Ppat.1000394  0.716
2009 Kural C, Kirchhausen T. Three Dimensional Imaging of Clathrin Coat Dynamics in Living Cells and Tissues Biophysical Journal. 96: 272a. DOI: 10.1016/J.Bpj.2008.12.1347  0.373
2008 Saffarian S, Kirchhausen T. Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane. Biophysical Journal. 94: 2333-42. PMID 17993495 DOI: 10.1529/Biophysj.107.117234  0.716
2007 Veiga E, Guttman JA, Bonazzi M, Boucrot E, Toledo-Arana A, Lin AE, Enninga J, Pizarro-Cerdá J, Finlay BB, Kirchhausen T, Cossart P. Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host & Microbe. 2: 340-51. PMID 18005755 DOI: 10.1016/J.Chom.2007.10.001  0.324
2007 Li J, Peters PJ, Bai M, Dai J, Bos E, Kirchhausen T, Kandror KV, Hsu VW. An ACAP1-containing clathrin coat complex for endocytic recycling. The Journal of Cell Biology. 178: 453-64. PMID 17664335 DOI: 10.1083/Jcb.200608033  0.369
2007 Kirchhausen T. Making COPII coats. Cell. 129: 1251-2. PMID 17604713 DOI: 10.1016/J.Cell.2007.06.015  0.419
2007 Wang J, Sun HQ, Macia E, Kirchhausen T, Watson H, Bonifacino JS, Yin HL. PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Molecular Biology of the Cell. 18: 2646-55. PMID 17494868 DOI: 10.1091/Mbc.E06-10-0897  0.328
2007 Boucrot E, Kirchhausen T. Endosomal recycling controls plasma membrane area during mitosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 7939-44. PMID 17483462 DOI: 10.1073/Pnas.0702511104  0.363
2007 Ma YM, Boucrot E, Villén J, Affar el B, Gygi SP, Göttlinger HG, Kirchhausen T. Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. The Journal of Biological Chemistry. 282: 9805-12. PMID 17261583 DOI: 10.1074/Jbc.M611635200  0.337
2007 Yu A, Rual JF, Tamai K, Harada Y, Vidal M, He X, Kirchhausen T. Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Developmental Cell. 12: 129-41. PMID 17199046 DOI: 10.1016/J.Devcel.2006.10.015  0.347
2007 Cheng Y, Boll W, Kirchhausen T, Harrison SC, Walz T. Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. Journal of Molecular Biology. 365: 892-9. PMID 17095010 DOI: 10.1016/J.Jmb.2006.10.036  0.602
2007 Cheng Y, Boll W, Kirchhausen T, Harrison S, Walz T. Visualization of Clathrin-coated Vesicles by Cryo-electron Tomography Microscopy and Microanalysis. 13. DOI: 10.1017/S143192760707198X  0.509
2006 Boucrot E, Saffarian S, Massol R, Kirchhausen T, Ehrlich M. Role of lipids and actin in the formation of clathrin-coated pits. Experimental Cell Research. 312: 4036-48. PMID 17097636 DOI: 10.1016/J.Yexcr.2006.09.025  0.731
2006 Falcone S, Cocucci E, Podini P, Kirchhausen T, Clementi E, Meldolesi J. Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events. Journal of Cell Science. 119: 4758-69. PMID 17077125 DOI: 10.1242/Jcs.03238  0.742
2006 Fotin A, Kirchhausen T, Grigorieff N, Harrison SC, Walz T, Cheng Y. Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. Journal of Structural Biology. 156: 453-60. PMID 16908193 DOI: 10.1016/J.Jsb.2006.07.001  0.733
2006 Massol RH, Boll W, Griffin AM, Kirchhausen T. A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating. Proceedings of the National Academy of Sciences of the United States of America. 103: 10265-70. PMID 16798879 DOI: 10.1073/Pnas.0603369103  0.463
2006 Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, Kirchhausen T. Dynasore, a cell-permeable inhibitor of dynamin. Developmental Cell. 10: 839-50. PMID 16740485 DOI: 10.1016/J.Devcel.2006.04.002  0.434
2006 Pelish HE, Peterson JR, Salvarezza SB, Rodriguez-Boulan E, Chen JL, Stamnes M, Macia E, Feng Y, Shair MD, Kirchhausen T. Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nature Chemical Biology. 2: 39-46. PMID 16408091 DOI: 10.1038/Nchembio751  0.358
2005 Keefe D, Shi L, Feske S, Massol R, Navarro F, Kirchhausen T, Lieberman J. Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis. Immunity. 23: 249-62. PMID 16169498 DOI: 10.1016/J.Immuni.2005.08.001  0.347
2005 Massol RH, Larsen JE, Kirchhausen T. Possible role of deep tubular invaginations of the plasma membrane in MHC-I trafficking. Experimental Cell Research. 306: 142-9. PMID 15878340 DOI: 10.1016/J.Yexcr.2005.01.021  0.385
2005 Paleotti O, Macia E, Luton F, Klein S, Partisani M, Chardin P, Kirchhausen T, Franco M. The small G-protein Arf6GTP recruits the AP-2 adaptor complex to membranes. The Journal of Biological Chemistry. 280: 21661-6. PMID 15802264 DOI: 10.1074/jbc.M503099200  0.302
2005 Kirchhausen T, Boll W, van Oijen A, Ehrlich M. Single-molecule live-cell imaging of clathrin-based endocytosis. Biochemical Society Symposium. 71-6. PMID 15649131 DOI: 10.1042/Bss0720071  0.443
2004 Fotin A, Cheng Y, Grigorieff N, Walz T, Harrison SC, Kirchhausen T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature. 432: 649-53. PMID 15502813 DOI: 10.1038/Nature03078  0.767
2004 Fotin A, Cheng Y, Sliz P, Grigorieff N, Harrison SC, Kirchhausen T, Walz T. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature. 432: 573-9. PMID 15502812 DOI: 10.1038/Nature03079  0.76
2004 Heldwein EE, Macia E, Wang J, Yin HL, Kirchhausen T, Harrison SC. Crystal structure of the clathrin adaptor protein 1 core. Proceedings of the National Academy of Sciences of the United States of America. 101: 14108-13. PMID 15377783 DOI: 10.1073/Pnas.0406102101  0.576
2004 Ehrlich M, Boll W, Van Oijen A, Hariharan R, Chandran K, Nibert ML, Kirchhausen T. Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell. 118: 591-605. PMID 15339664 DOI: 10.1016/J.Cell.2004.08.017  0.435
2004 Cerny J, Feng Y, Yu A, Miyake K, Borgonovo B, Klumperman J, Meldolesi J, McNeil PL, Kirchhausen T. The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. Embo Reports. 5: 883-8. PMID 15332114 DOI: 10.1038/Sj.Embor.7400243  0.554
2004 Nieland TJ, Feng Y, Brown JX, Chuang TD, Buckett PD, Wang J, Xie XS, McGraw TE, Kirchhausen T, Wessling-Resnick M. Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic. Traffic (Copenhagen, Denmark). 5: 478-92. PMID 15180825 DOI: 10.1111/J.1398-9219.2004.00193.X  0.32
2004 Feng Y, Jadhav AP, Rodighiero C, Fujinaga Y, Kirchhausen T, Lencer WI. Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells. Embo Reports. 5: 596-601. PMID 15153932 DOI: 10.1038/Sj.Embor.7400152  0.323
2004 Nieland TJ, Chroni A, Fitzgerald ML, Maliga Z, Zannis VI, Kirchhausen T, Krieger M. Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. Journal of Lipid Research. 45: 1256-65. PMID 15102890 DOI: 10.1194/Jlr.M300358-Jlr200  0.303
2004 Larsen JE, Massol RH, Nieland TJ, Kirchhausen T. HIV Nef-mediated major histocompatibility complex class I down-modulation is independent of Arf6 activity. Molecular Biology of the Cell. 15: 323-31. PMID 14617802 DOI: 10.1091/Mbc.E03-08-0578  0.306
2003 Wang YJ, Wang J, Sun HQ, Martinez M, Sun YX, Macia E, Kirchhausen T, Albanesi JP, Roth MG, Yin HL. Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell. 114: 299-310. PMID 12914695 DOI: 10.1016/S0092-8674(03)00603-2  0.354
2003 Feng Y, Yu S, Lasell TK, Jadhav AP, Macia E, Chardin P, Melancon P, Roth M, Mitchison T, Kirchhausen T. Exo1: a new chemical inhibitor of the exocytic pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 6469-74. PMID 12738886 DOI: 10.1073/Pnas.0631766100  0.301
2002 Boll W, Rapoport I, Brunner C, Modis Y, Prehn S, Kirchhausen T. The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites. Traffic (Copenhagen, Denmark). 3: 590-600. PMID 12121421 DOI: 10.1034/J.1600-0854.2002.30808.X  0.644
2002 Kirchhausen T. Clathrin adaptors really adapt. Cell. 109: 413-6. PMID 12086597 DOI: 10.1016/S0092-8674(02)00751-1  0.338
2001 Lederkremer GZ, Cheng Y, Petre BM, Vogan E, Springer S, Schekman R, Walz T, Kirchhausen T. Structure of the Sec23p/24p and Sec13p/31p complexes of COPII. Proceedings of the National Academy of Sciences of the United States of America. 98: 10704-9. PMID 11535824 DOI: 10.1073/Pnas.191359398  0.373
2000 Kirchhausen T. Three ways to make a vesicle. Nature Reviews. Molecular Cell Biology. 1: 187-98. PMID 11252894 DOI: 10.1038/35043117  0.412
2000 Kirchhausen T. Clathrin. Annual Review of Biochemistry. 69: 699-727. PMID 10966473 DOI: 10.1146/annurev.biochem.69.1.699  0.306
2000 Chen F, Ma L, Parrini MC, Mao X, Lopez M, Wu C, Marks PW, Davidson L, Kwiatkowski DJ, Kirchhausen T, Orkin SH, Rosen FS, Mayer BJ, Kirschner MW, Alt FW. Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability. Current Biology : Cb. 10: 758-65. PMID 10898977 DOI: 10.1016/S0960-9822(00)00571-6  0.333
2000 ter Haar E, Harrison SC, Kirchhausen T. Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin. Proceedings of the National Academy of Sciences of the United States of America. 97: 1096-100. PMID 10655490 DOI: 10.1073/Pnas.97.3.1096  0.493
1999 Kirchhausen T. Adaptors for clathrin-mediated traffic. Annual Review of Cell and Developmental Biology. 15: 705-32. PMID 10611976 DOI: 10.1146/Annurev.Cellbio.15.1.705  0.431
1999 Jones AT, Spiro DJ, Kirchhausen T, Melançon P, Wessling-Resnick M. Studies on the inhibition of endosome fusion by GTPgammaS-bound ARF. Journal of Cell Science. 112: 3477-85. PMID 10504296  0.325
1999 Musacchio A, Smith CJ, Roseman AM, Harrison SC, Kirchhausen T, Pearse BM. Functional organization of clathrin in coats: combining electron cryomicroscopy and X-ray crystallography. Molecular Cell. 3: 761-70. PMID 10394364 DOI: 10.1016/S1097-2765(01)80008-3  0.586
1999 Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell. 97: 221-31. PMID 10219243 DOI: 10.1016/S0092-8674(00)80732-1  0.305
1998 ter Haar E, Musacchio A, Harrison SC, Kirchhausen T. Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker. Cell. 95: 563-73. PMID 9827808 DOI: 10.1016/S0092-8674(00)81623-2  0.52
1998 Greenberg M, DeTulleo L, Rapoport I, Skowronski J, Kirchhausen T. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Current Biology : Cb. 8: 1239-42. PMID 9811611 DOI: 10.1016/S0960-9822(07)00518-0  0.752
1998 Sanderfoot AA, Ahmed SU, Marty-Mazars D, Rapoport I, Kirchhausen T, Marty F, Raikhel NV. A putative vacuolar cargo receptor partially colocalizes with AtPEP12p on a prevacuolar compartment in Arabidopsis roots Proceedings of the National Academy of Sciences of the United States of America. 95: 9920-9925. PMID 9707576 DOI: 10.1073/Pnas.95.17.9920  0.412
1998 DeTulleo L, Kirchhausen T. The clathrin endocytic pathway in viral infection Embo Journal. 17: 4585-4593. PMID 9707418 DOI: 10.1093/Emboj/17.16.4585  0.734
1998 Kamiguchi H, Long KE, Pendergast M, Schaefer AW, Rapoport I, Kirchhausen T, Lemmon V. The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5311-21. PMID 9651214 DOI: 10.1523/Jneurosci.18-14-05311.1998  0.343
1998 Rapoport I, Chen YC, Cupers P, Shoelson SE, Kirchhausen T. Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site. The Embo Journal. 17: 2148-55. PMID 9545228 DOI: 10.1093/Emboj/17.8.2148  0.378
1998 Cupers P, Jadhav AP, Kirchhausen T. Assembly of clathrin coats disrupts the association between Eps15 and AP-2 adaptors. The Journal of Biological Chemistry. 273: 1847-50. PMID 9442014 DOI: 10.1074/Jbc.273.4.1847  0.439
1998 Tong X, Boll W, Kirchhausen T, Howley PM. Interaction of the bovine papillomavirus E6 protein with the clathrin adaptor complex AP-1 Journal of Virology. 72: 476-482. PMID 9420248 DOI: 10.1128/Jvi.72.1.476-482.1998  0.389
1997 Cupers P, ter Haar E, Boll W, Kirchhausen T. Parallel dimers and anti-parallel tetramers formed by epidermal growth factor receptor pathway substrate clone 15. The Journal of Biological Chemistry. 272: 33430-4. PMID 9407139 DOI: 10.1074/Jbc.272.52.33430  0.383
1997 Clairmont KB, Boll W, Ericsson M, Kirchhausen T. A role for the hinge/ear domain of the β chains in the incorporation of AP complexes into clathrin-coated pits and coated vesicles Cellular and Molecular Life Sciences. 53: 611-619. PMID 9284964 DOI: 10.1007/S000180050080  0.431
1997 Kirchhausen T, Bonifacino JS, Riezman H. Linking cargo to vesicle formation: Receptor tail interactions with coat proteins Current Opinion in Cell Biology. 9: 488-495. PMID 9261055 DOI: 10.1016/S0955-0674(97)80024-5  0.444
1997 Rapoport I, Miyazaki M, Boll W, Duckworth B, Cantley LC, Shoelson S, Kirchhausen T. Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes Embo Journal. 16: 2240-2250. PMID 9171339 DOI: 10.1093/Emboj/16.9.2240  0.437
1996 Boll W, Ohno H, Songyang Z, Rapoport I, Cantley LC, Bonifacino JS, Kirchhausen T. Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes Embo Journal. 15: 5789-5795. PMID 8918456 DOI: 10.1002/J.1460-2075.1996.Tb00965.X  0.382
1996 Tebar F, Sorkina T, Sorkin A, Ericsson M, Kirchhausen T. Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits Journal of Biological Chemistry. 271: 28727-28730. PMID 8910509 DOI: 10.1074/Jbc.271.46.28727  0.464
1996 Spiro DJ, Boll W, Kirchhausen T, Wessling-Resnick M. Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro Molecular Biology of the Cell. 7: 355-367. PMID 8868465 DOI: 10.1091/Mbc.7.3.355  0.335
1996 Kolluri R, Tolias KF, Carpenter CL, Rosen FS, Kirchhausen T. Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42. Proceedings of the National Academy of Sciences of the United States of America. 93: 5615-8. PMID 8643625 DOI: 10.1073/Pnas.93.11.5615  0.301
1995 Boll W, Gallusser A, Kirchhausen T. Role of the regulatory domain of the EGF-receptor cytoplasmic tail in selective binding of the clathrin-associated complex AP-2 Current Biology. 5: 1168-1178. PMID 8548289 DOI: 10.1016/S0960-9822(95)00233-8  0.351
1995 Shih W, Gallusser A, Kirchhausen T. A clathrin-binding site in the hinge of the β2 chain of mammalian AP-2 complexes Journal of Biological Chemistry. 270: 31083-31090. PMID 8537368 DOI: 10.1074/Jbc.270.52.31083  0.402
1995 Speelman BA, Alien K, Grounds TL, Neutra MR, Kirchhausen T, Wilson JM. Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells Journal of Biological Chemistry. 270: 1583-1588. PMID 7829488 DOI: 10.1074/Jbc.270.4.1583  0.344
1995 Sorkin A, McKinsey T, Shih W, Kirchhausen T, Carpenter G. Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2 Journal of Biological Chemistry. 270: 619-625. PMID 7822287 DOI: 10.1074/Jbc.270.2.619  0.323
1995 Stepp JD, Pellicena-Palle A, Hamilton S, Kirchhausen T, Lemmon SK. A late golgi sorting function for Saccharomyces cerevisiae Apmlp, but not for Apm2p, a second yeast clathrin AP medium chain-related protein Molecular Biology of the Cell. 6: 41-58. PMID 7749194 DOI: 10.1091/Mbc.6.1.41  0.368
1995 Ohno H, Stewart J, Fournier MC, Bosshart H, Rhee I, Miyatake S, Saito T, Gallusser A, Kirchhausen T, Bonifacino JS. Interaction of tyrosine-based sorting signals with clathrin-associated proteins Science. 269: 1872-1875. PMID 7569928 DOI: 10.1126/Science.7569928  0.368
1994 Phan HL, Finlay JA, Chu DS, Tan PK, Kirchhausen T, Payne GS. The Saccharomyces cerevisiae APS1 gene encodes a homolog of the small subunit of the mammalian clathrin AP-1 complex: evidence for functional interaction with clathrin at the Golgi complex. The Embo Journal. 13: 1706-17. PMID 8157009 DOI: 10.1002/J.1460-2075.1994.Tb06435.X  0.409
1994 Søgaard M, Tani K, Ye RR, Geromanos S, Tempst P, Kirchhausen T, Rothman JE, Söllner T. A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell. 78: 937-48. PMID 7923363 DOI: 10.1016/0092-8674(94)90270-4  0.35
1994 Osborn L, Vassallo C, Browning BG, Tizard R, Haskard DO, Benjamin CD, Dougas I, Kirchhausen T. Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha 4 beta 1). The Journal of Cell Biology. 124: 601-8. PMID 7508942 DOI: 10.1083/Jcb.124.4.601  0.307
1993 Kirchhausen T. Coated pits and coated vesicles - sorting it all out Current Opinion in Structural Biology. 3: 182-188. DOI: 10.1016/S0959-440X(05)80150-2  0.44
1993 Gallusser A, Kirchhausen T. The beta 1 and beta 2 subunits of the AP complexes are the clathrin coat assembly components. The Embo Journal. 12: 5237-5244. DOI: 10.1002/J.1460-2075.1993.Tb06219.X  0.339
1991 Nakayama Y, Goebl M, O'Brine Greco B, Lemmon S, Pingchang Chow E, Kirchhausen T. The medium chains of the mammalian clathrin-associated proteins have a homolog in yeast European Journal of Biochemistry. 202: 569-574. PMID 1761056 DOI: 10.1111/J.1432-1033.1991.Tb16409.X  0.342
1990 Matsui W, Kirchhausen T. Stabilization of clathrin coats by the core of the clathrin-associated protein complex AP-2 Biochemistry. 29: 10791-10798. PMID 2125494 DOI: 10.1021/Bi00500A011  0.415
1990 Kirchhausen T. Identification of a putative yeast homolog of the mammalian β chains of the clathrin-associated protein complexes Molecular and Cellular Biology. 10: 6089-6090. PMID 2122239 DOI: 10.1128/Mcb.10.11.6089  0.432
1989 Kirchhausen T, Nathanson KL, Matsui W, Vaisberg A, Chow EP, Burne C, Keen JH, Davis AE. Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2 Proceedings of the National Academy of Sciences of the United States of America. 86: 2612-2616. PMID 2495531 DOI: 10.1073/Pnas.86.8.2612  0.37
1987 Kirchhausen T, Scarmato P, Harrison SC, Monroe JJ, Chow EP, Mattaliano RJ, Ramachandran KL, Smart JE, Ahn AH, Brosius J. Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs. Science (New York, N.Y.). 236: 320-4. PMID 3563513 DOI: 10.1126/science.3563513  0.392
1987 Kirchhausen T, Harrison SC, Chow EP, Mattaliano RJ, Ramachandran KL, Smart J, Brosius J. Clathrin heavy chain: molecular cloning and complete primary structure. Proceedings of the National Academy of Sciences of the United States of America. 84: 8805-9. PMID 3480512 DOI: 10.1073/Pnas.84.24.8805  0.478
1986 Kirchhausen T, Harrison SC, Heuser J. Configuration of clathrin trimers: evidence from electron microscopy. Journal of Ultrastructure and Molecular Structure Research. 94: 199-208. PMID 3805786 DOI: 10.1016/0889-1605(86)90067-4  0.492
1985 Kirchhausen T, Wang JC, Harrison SC. DNA gyrase and its complexes with DNA: direct observation by electron microscopy. Cell. 41: 933-43. PMID 2988794 DOI: 10.1016/S0092-8674(85)80074-X  0.431
1985 Heuser J, Kirchhausen T. Deep-etch views of clathrin assemblies Journal of Ultrastructure Research and Molecular Structure Research. 92: 1-27. PMID 2870198 DOI: 10.1016/0889-1605(85)90123-5  0.341
1984 Kirchhausen T, Harrison SC. Structural domains of clathrin heavy chains. The Journal of Cell Biology. 99: 1725-34. PMID 6386825 DOI: 10.1083/Jcb.99.5.1725  0.484
1983 León V, Kirchhausen T, Avila EM, Mateu L. Thermal effects in human plasma high density lipoproteins (HDL)3: a 13C-FT-NMR study Acta Cientifica Venezolana. 34: 209-215. PMID 6544544  0.539
1983 Hogle J, Kirchhausen T, Harrison SC. Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution. Journal of Molecular Biology. 171: 95-100. PMID 6417343 DOI: 10.1016/S0022-2836(83)80315-5  0.63
1983 Kirchhausen T, Harrison SC, Parham P, Brodsky FM. Location and distribution of the light chains in clathrin trimers. Proceedings of the National Academy of Sciences of the United States of America. 80: 2481-5. PMID 6189124 DOI: 10.1073/Pnas.80.9.2481  0.441
1983 Harrison SC, Kirchhausen T. Clathrin, cages, and coated vesicles. Cell. 33: 650-2. PMID 6135512 DOI: 10.1016/0092-8674(83)90007-7  0.561
1981 Kirchhausen T, Harrison SC. Protein organization in clathrin trimers. Cell. 23: 755-61. PMID 7226229 DOI: 10.1016/0092-8674(81)90439-6  0.471
1980 Kirchhausen T, Fless G, Scanu AM. The structure of plasma low density lipoproteins: Experimental facts and interpretations-A minireview Lipids. 15: 464-467. PMID 6772911 DOI: 10.1007/Bf02534073  0.309
1979 Mateu L, Kirchhausen T. Kinetics of thermal transitions in human serum low density lipoproteins (LDL) and neutral lipids. A dynamic small-angle X-ray scattering study Acta Cientifica Venezolana. 30: 478-483. PMID 232603  0.547
1978 Mateu L, Kirchhausen T, Camejo G. Small-angle X-ray scattering and differential scanning calorimetry studies on reversibly modified human-serum low density lipoproteins. Biochemistry. 17: 1436-40. PMID 206277 DOI: 10.1021/Bi00601A012  0.583
1978 Mateu L, Kirchhausen T, Camejo G. Small-angle x-ray scattering and differential scanning calorimetry studies on reversibly modified human-serum low density lipoproteins Biochemistry. 17: 1436-1440.  0.536
1977 Mateu L, Kirchhausen T, Padron R, Camejo G. Small angle X.ray scattering study of human serum low density lipoproteins with differential reactivity for an arterial proteoglycan Journal of Supramolecular and Cellular Biochemistry. 7: 435-442. PMID 211349 DOI: 10.1002/Jss.400070314  0.701
1977 Mateu L, Kirchhausen T, Camejo G. A low temperature structural transition in human serum low density lipoproteins Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 487: 243-245. PMID 192306 DOI: 10.1016/0005-2760(77)90060-1  0.573
Low-probability matches (unlikely to be authored by this person)
2004 Boll W, Ehrlich M, Collier RJ, Kirchhausen T. Effects of dynamin inactivation on pathways of anthrax toxin uptake. European Journal of Cell Biology. 83: 281-8. PMID 15511085 DOI: 10.1078/0171-9335-00373  0.299
2002 Nieland TJ, Penman M, Dori L, Krieger M, Kirchhausen T. Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proceedings of the National Academy of Sciences of the United States of America. 99: 15422-7. PMID 12438696 DOI: 10.1073/Pnas.222421399  0.299
2015 Wittrup A, Ai A, Liu X, Hamar P, Trifonova R, Charisse K, Manoharan M, Kirchhausen T, Lieberman J. Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown. Nature Biotechnology. PMID 26192320 DOI: 10.1038/Nbt.3298  0.297
2008 Ambrogio C, Voena C, Manazza AD, Martinengo C, Costa C, Kirchhausen T, Hirsch E, Inghirami G, Chiarle R. The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation. Cancer Research. 68: 8899-907. PMID 18974134 DOI: 10.1158/0008-5472.Can-08-2568  0.297
1993 Kirchhausen T, Staunton DE, Springer TA. Location of the domains of ICAM-1 by immunolabeling and single-molecule electron microscopy Journal of Leukocyte Biology. 53: 342-346. PMID 8095966 DOI: 10.1002/Jlb.53.3.342  0.296
2003 Boes M, Bertho N, Cerny J, Op den Brouw M, Kirchhausen T, Ploegh H. T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 171: 4081-8. PMID 14530329 DOI: 10.4049/Jimmunol.171.8.4081  0.293
2015 Gaudin R, Kirchhausen T. Superinfection exclusion is absent during acute Junin virus infection of Vero and A549 cells. Scientific Reports. 5: 15990. PMID 26549784 DOI: 10.1038/Srep15990  0.292
2000 Farr GW, Furtak K, Rowland MB, Ranson NA, Saibil HR, Kirchhausen T, Horwich AL. Multivalent binding of nonnative substrate proteins by the chaperonin GroEL. Cell. 100: 561-73. PMID 10721993 DOI: 10.1016/S0092-8674(00)80692-3  0.292
2012 Strang BL, Boulant S, Kirchhausen T, Coen DM. Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments. Mbio. 3. PMID 22318319 DOI: 10.1128/Mbio.00301-11  0.289
2005 Nieland TJ, Ehrlich M, Krieger M, Kirchhausen T. Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI. Biochimica Et Biophysica Acta. 1734: 44-51. PMID 15866482 DOI: 10.1016/J.Bbalip.2005.02.007  0.288
2008 Rapoport I, Boll W, Yu A, Böcking T, Kirchhausen T. A motif in the clathrin heavy chain required for the Hsc70/auxilin uncoating reaction. Molecular Biology of the Cell. 19: 405-13. PMID 17978091 DOI: 10.1091/mbc.E07-09-0870  0.287
1996 Bunnell SC, Henry PA, Kolluri R, Kirchhausen T, Rickles RJ, Berg LJ. Identification of Itk/Tsk Src homology 3 domain ligands. The Journal of Biological Chemistry. 271: 25646-56. PMID 8810341 DOI: 10.1074/Jbc.271.41.25646  0.287
2014 Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J. Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes. Cell. 157: 1309-23. PMID 24906149 DOI: 10.1016/J.Cell.2014.03.062  0.285
1995 Rad MR, Phan HL, Kirchrath L, Tan PK, Kirchhausen T, Hollenberg CP, Payne GS. Saccharomyces cerevisiae Apl2p, a homologue of the mammalian clathrin AP beta subunit, plays a role in clathrin-dependent Golgi functions. Journal of Cell Science. 108: 1605-15. PMID 7615679  0.284
2015 Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J. Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes. Cell. 161: 1229. PMID 28910642 DOI: 10.1016/J.Cell.2015.05.021  0.278
2017 Paulsen BS, Mandal PK, Frock RL, Boyraz B, Yadav R, Upadhyayula S, Gutierrez-Martinez P, Ebina W, Fasth A, Kirchhausen T, Talkowski ME, Agarwal S, Alt FW, Rossi DJ. Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing. Nature Biomedical Engineering. 1: 878-888. PMID 31015609 DOI: 10.1038/S41551-017-0145-2  0.277
2003 Chandran K, Parker JS, Ehrlich M, Kirchhausen T, Nibert ML. The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. Journal of Virology. 77: 13361-75. PMID 14645591 DOI: 10.1128/Jvi.77.24.13361-13375.2003  0.276
2012 Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 11: 242-52. PMID 22862949 DOI: 10.1016/J.Stem.2012.04.025  0.275
2013 Martinelli R, Kamei M, Sage PT, Massol R, Varghese L, Sciuto T, Toporsian M, Dvorak AM, Kirchhausen T, Springer TA, Carman CV. Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds. The Journal of Cell Biology. 201: 449-65. PMID 23629967 DOI: 10.1083/Jcb.201209077  0.271
2007 Shair M, Kirchhausen T, Hannoush R, Goess B. Reversible Small Molecule Induced Separation of Mammalian Golgi Cisternae The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A149-B  0.27
2008 Boucrot E, Kirchhausen T. Mammalian cells change volume during mitosis. Plos One. 3: e1477. PMID 18213385 DOI: 10.1371/Journal.Pone.0001477  0.27
2009 Shulman Z, Shinder V, Klein E, Grabovsky V, Yeger O, Geron E, Montresor A, Bolomini-Vittori M, Feigelson SW, Kirchhausen T, Laudanna C, Shakhar G, Alon R. Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. Immunity. 30: 384-96. PMID 19268609 DOI: 10.1016/J.Immuni.2008.12.020  0.269
1979 Kirchhausen T, Untracht SH, Fless GM, Scanu AM. Atherogenic diets and neutral-lipid organization in plasma low density lipoproteins Atherosclerosis. 33: 59-70. PMID 223602 DOI: 10.1016/0021-9150(79)90198-9  0.267
2007 Jiang S, Zhou X, Kirchhausen T, Wong ST. Tracking molecular particles in live cells using fuzzy rule-based system. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 576-84. PMID 17542029 DOI: 10.1002/cyto.a.20411  0.265
2002 Schaefer AW, Kamei Y, Kamiguchi H, Wong EV, Rapoport I, Kirchhausen T, Beach CM, Landreth G, Lemmon SK, Lemmon V. L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. The Journal of Cell Biology. 157: 1223-32. PMID 12082080 DOI: 10.1083/Jcb.200203024  0.264
1997 Kirchhausen T, Pines J, Toldo L, Lafont F. Web Alert Membranes And Sorting Membrane Permeability Current Opinion in Cell Biology. 9: 473-473. PMID 9261064 DOI: 10.1016/S0955-0674(97)80020-8  0.264
2012 Strang BL, Boulant S, Chang L, Knipe DM, Kirchhausen T, Coen DM. Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis. Journal of Virology. 86: 2089-95. PMID 22156516 DOI: 10.1128/Jvi.06720-11  0.263
2012 Kural C, Kirchhausen T. Live-cell imaging of clathrin coats. Methods in Enzymology. 505: 59-80. PMID 22289448 DOI: 10.1016/B978-0-12-388448-0.00012-7  0.262
1982 Fless GM, Kirchhausen T, Fischer-Dzoga K, Wissler RW, Scanu AM. Serum low density lipoproteins with mitogenic effect on cultured aortic smooth muscle cells. Atherosclerosis. 41: 171-83. PMID 7066069 DOI: 10.1016/0021-9150(82)90183-6  0.261
2003 Yarrow JC, Feng Y, Perlman ZE, Kirchhausen T, Mitchison TJ. Phenotypic screening of small molecule libraries by high throughput cell imaging. Combinatorial Chemistry & High Throughput Screening. 6: 279-86. PMID 12769670 DOI: 10.2174/138620703106298527  0.261
1990 Tucker KL, Nathanson K, Kirchhausen T. Sequence of the rat αc large chain of the clathrin associated protein complex AP-2 Nucleic Acids Research. 18: 5306. PMID 2402467 DOI: 10.1093/Nar/18.17.5306  0.261
2020 Bloyet LM, Morin B, Brusic V, Gardner E, Ross RA, Vadakkan T, Kirchhausen T, Whelan SPJ. Oligomerization of the vesicular stomatitis virus phosphoprotein is dispensable for mRNA synthesis but facilitates RNA replication. Journal of Virology. PMID 32321813 DOI: 10.1128/Jvi.00115-20  0.259
2014 Carmo-Fonseca M, Kirchhausen T. The timing of pre-mRNA splicing visualized in real-time. Nucleus (Austin, Tex.). 5: 11-4. PMID 24637398 DOI: 10.4161/Nucl.28056  0.257
2004 Massol RH, Larsen JE, Fujinaga Y, Lencer WI, Kirchhausen T. Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways. Molecular Biology of the Cell. 15: 3631-41. PMID 15146065 DOI: 10.1091/Mbc.E04-04-0283  0.255
2015 Ishikawa Y, Maeda M, Pasham M, Aguet F, Tacheva-Grigorova SK, Masuda T, Yi H, Lee SU, Xu J, Teruya-Feldstein J, Ericsson M, Mullally A, Heuser J, Kirchhausen T, Maeda T. Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology. Haematologica. 100: 439-51. PMID 25552701 DOI: 10.3324/haematol.2014.119537  0.252
2013 Martin RM, Rino J, Carvalho C, Kirchhausen T, Carmo-Fonseca M. Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity. Cell Reports. 4: 1144-55. PMID 24035393 DOI: 10.1016/J.Celrep.2013.08.013  0.249
2016 Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte M, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Kirchhausen T, et al. Author response: Seipin is required for converting nascent to mature lipid droplets Elife. DOI: 10.7554/Elife.16582.033  0.246
2020 Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, Jang E, Klein EM, Goldey GJ, He K, ... ... Kirchhausen T, et al. Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface. Neuron. PMID 32961128 DOI: 10.1016/J.Neuron.2020.08.024  0.245
2006 Xu B, Pelish H, Kirchhausen T, Hammond GB. Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading. Organic & Biomolecular Chemistry. 4: 4149-57. PMID 17312971 DOI: 10.1039/B609143A  0.245
2003 Legesse-Miller A, Massol RH, Kirchhausen T. Constriction and Dnm1p recruitment are distinct processes in mitochondrial fission. Molecular Biology of the Cell. 14: 1953-63. PMID 12802067 DOI: 10.1091/Mbc.E02-10-0657  0.243
2001 Pelish HE, Westwood NJ, Feng Y, Kirchhausen T, Shair MD. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. Journal of the American Chemical Society. 123: 6740-1. PMID 11439080 DOI: 10.1021/Ja016093H  0.243
2006 Goess BC, Hannoush RN, Chan LK, Kirchhausen T, Shair MD. Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors. Journal of the American Chemical Society. 128: 5391-403. PMID 16620111 DOI: 10.1021/Ja056338G  0.243
1991 Keen JH, Beck KA, Kirchhausen T, Jarrett T. Clathrin domains involved in recognition by assembly protein AP-2 Journal of Biological Chemistry. 266: 7950-7956. PMID 1902233  0.242
2007 Jiang S, Zhou X, Kirchhausen T, Wong ST. Detection of molecular particles in live cells via machine learning. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 563-75. PMID 17431884 DOI: 10.1002/cyto.a.20404  0.233
1996 Kirchhausen T, Rosen FS. Disease mechanism: Unravelling Wiskott-Aldrich syndrome Current Biology. 6: 676-678. PMID 8793292 DOI: 10.1016/S0960-9822(09)00447-3  0.233
2013 Tacheva-Grigorova SK, Santos AJ, Boucrot E, Kirchhausen T. Clathrin-mediated endocytosis persists during unperturbed mitosis. Cell Reports. 4: 659-68. PMID 23954786 DOI: 10.1016/j.celrep.2013.07.017  0.23
2012 Kirchhausen T. Bending membranes. Nature Cell Biology. 14: 906-8. PMID 22945258 DOI: 10.1038/ncb2570  0.228
1993 Gallusser A, Kirchhausen T. The β1 and β2 subunits of the AP complexes are the clathrin coat assembly components Embo Journal. 12: 5237-5244. PMID 8262066  0.228
1991 Kirchhausen T, Davis AC, Frucht S, Greco BO, Payne GS, Tubb B. AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast. The Journal of Biological Chemistry. 266: 11153-7. PMID 2040623  0.218
1988 Thurieau C, Brosius J, Burne C, Jolles P, Keen JH, Mattaliano RJ, Chow EP, Ramachandran KL, Kirchhausen T. Molecular cloning and complete amino acid sequence of AP50, an assembly protein associated with clathrin-coated vesicles. Dna (Mary Ann Liebert, Inc.). 7: 663-9. PMID 3148444  0.218
1993 Kirchhausen T, Toyoda T. Immunoelectron microscopic evidence for the extended conformation of light chains in clathrin trimers Journal of Biological Chemistry. 268: 10268-10273. PMID 7683673  0.213
2008 Kirchhausen T, Macia E, Pelish HE. Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis. Methods in Enzymology. 438: 77-93. PMID 18413242 DOI: 10.1016/S0076-6879(07)38006-3  0.212
1998 Kirchhausen T. Vesicle formation: dynamic dynamin lives up to its name. Current Biology : Cb. 8: R792-4. PMID 9811595  0.211
2005 Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A. The transcription factor NFAT3 mediates neuronal survival. The Journal of Biological Chemistry. 280: 2818-25. PMID 15537643 DOI: 10.1074/Jbc.M408741200  0.208
2015 Beerman I, Ziller M, Vandiver A, Gaudin R, Kirchhausen T, Feinberg A, Meissner A, Rossi D. AGE-associated clonal dominance of myeloid-biased HSC is underwritten by unique transcriptional and epigenetic alterations Experimental Hematology. 43: S49. DOI: 10.1016/J.Exphem.2015.06.065  0.203
2005 McNeil PL, Kirchhausen T. An emergency response team for membrane repair. Nature Reviews. Molecular Cell Biology. 6: 499-505. PMID 15928713 DOI: 10.1038/nrm1665  0.202
1999 Schneider H, Martin M, Agarraberes FA, Yin L, Rapoport I, Kirchhausen T, Rudd CE. Cytolytic T lymphocyte-associated antigen-4 and the TCR zeta/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2. Journal of Immunology (Baltimore, Md. : 1950). 163: 1868-79. PMID 10438921  0.202
2018 Swinburne IA, Mosaliganti KR, Upadhyayula S, Liu T, Hildebrand DGC, Tsai TYC, Chen A, Al-Obeidi E, Fass AK, Malhotra S, Engert F, Lichtman JW, Kirchhausen T, Betzig E, Megason SG. Author response: Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure Elife. DOI: 10.7554/Elife.37131.031  0.202
2006 Newton AJ, Kirchhausen T, Murthy VN. Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 17955-60. PMID 17093049 DOI: 10.1073/Pnas.0606212103  0.198
2009 Lu L, Ladinsky MS, Kirchhausen T. Cisternal organization of the endoplasmic reticulum during mitosis. Molecular Biology of the Cell. 20: 3471-80. PMID 19494040 DOI: 10.1091/mbc.E09-04-0327  0.196
2022 Bakkers MJG, Moon-Walker A, Herlo R, Brusic V, Stubbs SH, Hastie KM, Saphire EO, Kirchhausen TL, Whelan SPJ. CD164 is a host factor for lymphocytic choriomeningitis virus entry. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119676119. PMID 35235462 DOI: 10.1073/pnas.2119676119  0.188
1996 Bonifacino JS, Marks MS, Ohno H, Kirchhausen T. Mechanisms of signal-mediated protein sorting in the endocytic and secretory pathways. Proceedings of the Association of American Physicians. 108: 285-95. PMID 8863342  0.179
2022 Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, ... ... Kirchhausen T, et al. Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein. Biorxiv : the Preprint Server For Biology. PMID 35982670 DOI: 10.1101/2022.08.11.503553  0.179
2008 Nieland TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S, Zannis VI, Kirchhausen T, Krieger M. Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity. Biochemistry. 47: 460-72. PMID 18067275 DOI: 10.1021/Bi701277X  0.174
2012 Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S. Regulation of ligand-independent Notch signal through intracellular trafficking. Communicative & Integrative Biology. 5: 374-6. PMID 23060962 DOI: 10.4161/Cib.19995  0.174
2015 Reeves PM, Kang YL, Kirchhausen T. Endocytosis of ligand activated sphingosine 1-phosphate receptor 1 mediated by the clathrin-pathway. Traffic (Copenhagen, Denmark). PMID 26481905 DOI: 10.1111/Tra.12343  0.164
2011 Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S. Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal. The Journal of Cell Biology. 195: 1005-15. PMID 22162134 DOI: 10.1083/Jcb.201104146  0.162
2022 Stachowiak JC, Kirchhausen T. The beauty of simplicity in membrane biology. Nature Cell Biology. 24: 1682-1685. PMID 36266490 DOI: 10.1038/s41556-022-01015-6  0.159
2011 Lu L, Ladinsky MS, Kirchhausen T. Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly. The Journal of Cell Biology. 194: 425-40. PMID 21825076 DOI: 10.1083/jcb.201012063  0.155
2002 Boes M, Cerny J, Massol R, Op den Brouw M, Kirchhausen T, Chen J, Ploegh HL. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature. 418: 983-8. PMID 12198548 DOI: 10.1038/Nature01004  0.152
2006 Pelish HE, Ciesla W, Tanaka N, Reddy K, Shair MD, Kirchhausen T, Lencer WI. The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells. Biochemical Pharmacology. 71: 1720-6. PMID 16677615 DOI: 10.1016/J.Bcp.2006.03.011  0.148
2023 Yang K, Wang C, Kreutzberger AJB, White KI, Pfuetzner RA, Esquivies L, Kirchhausen T, Brunger AT. Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300360120. PMID 36940324 DOI: 10.1073/pnas.2300360120  0.145
2024 Hatzakis N, Kaestel-Hansen J, de Sautu M, Saminathan A, Scanavachi G, Correia R, Nielsen AJ, Bleshoey S, Boomsma W, Kirchhausen T. Deep learning assisted single particle tracking for automated correlation between diffusion and function. Research Square. PMID 38352328 DOI: 10.21203/rs.3.rs-3716053/v1  0.14
1990 Scarmato P, Kirchhausen T. Analysis of clathrin light chain-heavy chain interactions using truncated mutants of rat liver light chain LCB3 Journal of Biological Chemistry. 265: 3661-3668. PMID 2406259  0.132
2013 Lu L, Hannoush RN, Goess BC, Varadarajan S, Shair MD, Kirchhausen T. The small molecule dispergo tubulates the endoplasmic reticulum and inhibits export. Molecular Biology of the Cell. 24: 1020-9. PMID 23389632 DOI: 10.1091/Mbc.E12-08-0575  0.131
2002 Kirchhausen T. Single-handed recognition of a sorting traffic motif by the GGA proteins. Nature Structural Biology. 9: 241-4. PMID 11914729 DOI: 10.1038/nsb0402-241  0.125
2006 Pelish HE, Peterson JR, Salvarezza SB, Rodriguez-Boulan E, Chen J, Stamnes M, Macia E, Feng Y, Shair MD, Kirchhausen T. Erratum: Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro Nature Chemical Biology. 2: 221-221. DOI: 10.1038/nchembio0406-221b  0.117
1999 Kirchhausen T. Cell biology. Boa constrictor or rattlesnake? Nature. 398: 470-1. PMID 10206640 DOI: 10.1038/18989  0.117
1998 Kirchhausen T. Wiskott-Aldrich syndrome: a gene, a multifunctional protein and the beginnings of an explanation. Molecular Medicine Today. 4: 300-4. PMID 9743991 DOI: 10.1016/S1357-4310(98)01268-4  0.106
2010 Smits P, Bolton AD, Funari V, Hong M, Boyden ED, Lu L, Manning DK, Dwyer ND, Moran JL, Prysak M, Merriman B, Nelson SF, Bonafé L, Superti-Furga A, Ikegawa S, ... ... Kirchhausen T, et al. Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210. The New England Journal of Medicine. 362: 206-16. PMID 20089971 DOI: 10.1056/Nejmoa0900158  0.105
2014 Hagemann AIH, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S. Correction to In vivo analysis of formation and endocytosis of the Wnt/β-Catenin signaling complex in zebrafish embryos [J. Cell Sci. 127, (2014) 3970-3982] Journal of Cell Science. 127: 5331. DOI: 10.1242/jcs.165704  0.104
2006 Chan L, Kirchhausen T, Shair M, Goess B, Hannoush R. Diversity-Oriented Synthesis of a 10,102-Membered Library of Carpanones Synfacts. 2006: 0849-0849. DOI: 10.1055/s-2006-941985  0.019
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