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Stephen G. Waxman - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
pain, ion channels
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Year Citation  Score
2022 Ghovanloo MR, Estacion M, Higerd GP, Zhao P, Dib-Hajj S, Waxman SG. Inhibition of sodium conductance by cannabigerol contributes to a reduction of dorsal root ganglion neuron excitability. British Journal of Pharmacology. PMID 35297036 DOI: 10.1111/bph.15833  0.778
2022 Alsaloum M, Labau JIR, Liu S, Effraim P, Waxman SG. Stem cell-derived sensory neurons modelling inherited erythromelalgia: normalization of excitability. Brain : a Journal of Neurology. PMID 35088838 DOI: 10.1093/brain/awac031  0.817
2021 Labau JIR, Alsaloum M, Estacion M, Tanaka B, Dib-Hajj FB, Lauria G, Smeets HJM, Faber CG, Dib-Hajj S, Waxman SG. Lacosamide Inhibition of Na1.7 Channels Depends on its Interaction With the Voltage Sensor Domain and the Channel Pore. Frontiers in Pharmacology. 12: 791740. PMID 34992539 DOI: 10.3389/fphar.2021.791740  0.806
2021 Alsaloum M, Waxman SG. iPSCs and DRGs: stepping stones to new pain therapies. Trends in Molecular Medicine. PMID 34933815 DOI: 10.1016/j.molmed.2021.11.005  0.827
2021 Alsaloum M, Labau JIR, Liu S, Estacion M, Zhao P, Dib-Hajj F, Waxman SG. Contributions of Na1.8 and Na1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons. Scientific Reports. 11: 24283. PMID 34930944 DOI: 10.1038/s41598-021-03608-x  0.826
2021 Yuan JH, Estacion M, Mis MA, Tanaka BS, Schulman BR, Chen L, Liu S, Dib-Hajj FB, Dib-Hajj SD, Waxman SG. variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience. Brain Communications. 3: fcab212. PMID 34557669 DOI: 10.1093/braincomms/fcab212  0.78
2021 Alsaloum M, Labau JIR, Sosniak D, Zhao P, Almomani R, Gerrits M, Hoeijmakers JGJ, Lauria G, Faber CG, Waxman SG, Dib-Hajj S. A novel gain-of-function sodium channel β2 subunit mutation in idiopathic small fiber neuropathy. Journal of Neurophysiology. PMID 34320850 DOI: 10.1152/jn.00184.2021  0.811
2021 Renthal W, Chamessian A, Curatolo M, Davidson S, Burton M, Dib-Hajj S, Dougherty PM, Ebert AD, Gereau RW, Ghetti A, Gold MS, Hoben G, Menichella DM, Mercier P, Ray WZ, ... ... Waxman S, et al. Human cells and networks of pain: Transforming pain target identification and therapeutic development. Neuron. 109: 1426-1429. PMID 33957072 DOI: 10.1016/j.neuron.2021.04.005  0.427
2021 Benson CA, Olson KL, Patwa S, Reimer ML, Bangalore L, Hill M, Waxman SG, Tan AM. Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury. Scientific Reports. 11: 7838. PMID 33837249 DOI: 10.1038/s41598-021-87476-5  0.682
2021 Akin EJ, Alsaloum M, Higerd GP, Liu S, Zhao P, Dib-Hajj FB, Waxman SG, Dib-Hajj SD. Paclitaxel increases axonal localization and vesicular trafficking of Nav1.7. Brain : a Journal of Neurology. PMID 33734317 DOI: 10.1093/brain/awab113  0.819
2021 Honmou O, Yamashita T, Morita T, Oshigiri T, Hirota R, Iyama S, Kato J, Sasaki Y, Ishiai S, Ito YM, Namioka A, Namioka T, Nakazaki M, Kataoka-Sasaki Y, Onodera R, ... ... Waxman SG, et al. Intravenous infusion of auto serum-expanded autologous mesenchymal stem cells in spinal cord injury patients: 13 case series. Clinical Neurology and Neurosurgery. 203: 106565. PMID 33667953 DOI: 10.1016/j.clineuro.2021.106565  0.457
2020 Chen L, Wimalasena NK, Shim J, Han C, Lee SI, Gonzalez-Cano R, Estacion M, Faber CG, Lauria G, Dib-Hajj SG, Woolf CJ, Waxman SG. Two independent mouse lines carrying the Nav1.7-I228M gain-of-function variant display DRG neuron hyperexcitability but a minimal pain phenotype. Pain. PMID 33323889 DOI: 10.1097/j.pain.0000000000002171  0.515
2020 Cheng X, Choi JS, Waxman SG, Dib-Hajj SD. Mini-review - Sodium channels and beyond in peripheral nerve disease: Modulation by cytokines and their effector protein kinases. Neuroscience Letters. 135446. PMID 33166641 DOI: 10.1016/j.neulet.2020.135446  0.329
2020 Reimer ML, Bangalore L, Waxman SG, Tan AM. Core principles for the implementation of the neurodata without borders data standard. Journal of Neuroscience Methods. 108972. PMID 33157146 DOI: 10.1016/j.jneumeth.2020.108972  0.61
2020 Alsaloum M, Higerd GP, Effraim PR, Waxman SG. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nature Reviews. Neurology. PMID 33110213 DOI: 10.1038/s41582-020-00415-2  0.809
2020 Dong W, Jin SC, Allocco A, Zeng X, Sheth AH, Panchagnula S, Castonguay A, Lorenzo LÉ, Islam B, Brindle G, Bachand K, Hu J, Sularz A, Gaillard J, Choi J, ... ... Waxman SG, et al. Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia. Iscience. 23: 101552. PMID 33083721 DOI: 10.1016/J.Isci.2020.101552  0.352
2020 Nestler EJ, Waxman SG. Resilience to Stress and Resilience to Pain: Lessons from Molecular Neurobiology and Genetics. Trends in Molecular Medicine. 26: 924-935. PMID 32976800 DOI: 10.1016/j.molmed.2020.03.007  0.32
2020 Chen L, Huang J, Benson C, Lankford KL, Zhao P, Carrara J, Tan AM, Kocsis JD, Waxman SG, Dib-Hajj SD. Sodium channel Nav1.6 in sensory neurons contributes to vincristine-induced allodynia. Brain : a Journal of Neurology. PMID 32830219 DOI: 10.1093/Brain/Awaa208  0.793
2020 McMahon KL, Tay B, Deuis JR, Tanaka BS, Peigneur S, Jin AH, Tytgat J, Waxman SG, Dib-Hajj SD, Vetter I, Schroeder CI. Pharmacological activity and NMR solution structure of the leech peptide HSTX-I. Biochemical Pharmacology. 114082. PMID 32524995 DOI: 10.1016/J.Bcp.2020.114082  0.791
2020 Xenakis MN, Kapetis D, Yang Y, Heijman J, Waxman SG, Lauria G, Faber CG, Smeets HJM, Westra RL, Lindsey P. Cumulative hydropathic topology of a voltage-gated sodium channel at atomic resolution. Proteins. PMID 32447794 DOI: 10.1002/prot.25951  0.336
2020 Benson CA, Fenrich KK, Olson KL, Patwa S, Bangalore L, Waxman SG, Tan AM. Dendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32371602 DOI: 10.1523/Jneurosci.2858-19.2020  0.719
2020 Labau JI, Estacion M, Tanaka BS, de Greef BT, Hoeijmakers JG, Geerts M, Gerrits MM, Smeets HJ, Faber CG, Merkies IS, Lauria G, Dib-Hajj SD, Waxman SG. Differential effect of lacosamide on Nav1.7 variants from responsive and non-responsive patients with small fibre neuropathy. Brain : a Journal of Neurology. PMID 32011655 DOI: 10.1093/Brain/Awaa016  0.795
2020 Chen L, Effraim P, Carrara J, Zhao P, Dib-Hajj FB, Dib-Hajj SD, Waxman SG. Pharmacological characterization of a rat Nav1.7 loss-of-function model with insensitivity to pain. Pain. PMID 31977939 DOI: 10.1097/j.pain.0000000000001807  0.384
2020 Alsaloum M, Zhao P, Gerrits MM, Almomani R, Hoeijmakers J, Sopacua M, Lauria G, Faber CG, Dib-Hajj S, Waxman SG. Identification of a Novel Gain-of-Function Sodium Channel B2 Subunit Mutation in Small Fiber Neuropathy Biophysical Journal. 118: 578a-579a. DOI: 10.1016/j.bpj.2019.11.3141  0.792
2019 Patwa S, Benson CA, Dyer L, Olson KL, Bangalore L, Hill M, Waxman SG, Tan AM. Spinal cord motor neuron plasticity accompanies second-degree burn injury and chronic pain. Physiological Reports. 7: e14288. PMID 31858746 DOI: 10.14814/phy2.14288  0.712
2019 Sizova DV, Huang J, Akin EJ, Estacion M, Gomis-Perez C, Waxman SG, Dib-Hajj SD. A 49-residue sequence motif in the C-terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane. The Journal of Biological Chemistry. PMID 31822564 DOI: 10.1074/Jbc.Ra119.011424  0.371
2019 Urru M, Muzzi M, Coppi E, Ranieri G, Buonvicino D, Camaioni E, Coppini R, Pugliese AM, Tanaka B, Estacion M, Waxman SG, Dib-Hajj SD, Chiarugi A. Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models. Pain. PMID 31815915 DOI: 10.1097/J.Pain.0000000000001774  0.809
2019 Akin EJ, Higerd GP, Mis MA, Tanaka BS, Adi T, Liu S, Dib-Hajj FB, Waxman SG, Dib-Hajj SD. Building sensory axons: Delivery and distribution of Na1.7 channels and effects of inflammatory mediators. Science Advances. 5: eaax4755. PMID 31681845 DOI: 10.1126/Sciadv.Aax4755  0.815
2019 Huang J, Estacion M, Zhao P, Dib-Hajj FB, Schulman B, Abicht A, Kurth I, Brockmann K, Waxman SG, Dib-Hajj SD. A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain. Frontiers in Neuroscience. 13: 918. PMID 31551682 DOI: 10.3389/Fnins.2019.00918  0.431
2019 Grubinska B, Chen L, Alsaloum M, Rampal N, Matson D, Yang C, Taborn K, Zhang M, Youngblood B, Liu D, Galbreath E, Allred S, Lepherd M, Ferrando R, Kornecook T, ... ... Waxman S, et al. [EXPRESS] Rat NaV1.7 loss-of-function genetic model: deficient nociceptive and neuropathic pain behavior with retained olfactory function and intra-epidermal nerve fibers. Molecular Pain. 1744806919881846. PMID 31550995 DOI: 10.1177/1744806919881846  0.811
2019 Kiernan MC, Bostock H, Park SB, Kaji R, Krarup C, Krishnan AV, Kuwabara S, Lin CS, Misawa S, Moldovan M, Sung J, Vucic S, Wainger BJ, Waxman S, Burke D. Measurement of axonal excitability: Consensus guidelines. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 31471200 DOI: 10.1016/J.Clinph.2019.07.023  0.333
2019 Effraim PR, Huang J, Lampert A, Stamboulian S, Zhao P, Black JA, Dib-Hajj SD, Waxman SG. Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner. Neurobiology of Pain (Cambridge, Mass.). 6: 100029. PMID 31223136 DOI: 10.1016/J.Ynpai.2019.100029  0.638
2019 Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I. Na 1.6 regulates excitability of mechanosensitive sensory neurons. The Journal of Physiology. PMID 31087362 DOI: 10.1113/Jp278148  0.821
2019 Alsaloum M, Estacion M, Almomani R, Gerrits M, Bönhof G, Ziegler D, Malik R, Ferdousi M, Lauria G, Merkies I, Faber C, Dib-Hajj S, Waxman S. [EXPRESS] A gain-of-function sodium channel β2 subunit mutation in painful diabetic neuropathy. Molecular Pain. 1744806919849802. PMID 31041876 DOI: 10.1177/1744806919849802  0.807
2019 Vrselja Z, Daniele SG, Silbereis J, Talpo F, Morozov YM, Sousa AMM, Tanaka BS, Skarica M, Pletikos M, Kaur N, Zhuang ZW, Liu Z, Alkawadri R, Sinusas AJ, Latham SR, ... Waxman SG, et al. Restoration of brain circulation and cellular functions hours post-mortem. Nature. 568: 336-343. PMID 30996318 DOI: 10.1038/S41586-019-1099-1  0.754
2019 Bennett DL, Clark AJ, Huang J, Waxman SG, Dib-Hajj SD. The Role of Voltage-Gated Sodium Channels in Pain Signaling. Physiological Reviews. 99: 1079-1151. PMID 30672368 DOI: 10.1152/Physrev.00052.2017  0.441
2018 Geha P, Schulman BR, Dib-Hajj SD, Waxman SG. Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning. Neurobiology of Pain (Cambridge, Mass.). 3: 8-14. PMID 31080911 DOI: 10.1016/J.Ynpai.2018.01.002  0.317
2018 Hashimoto-Torii K, Sasaki M, Chang YW, Hwang H, Waxman SG, Kocsis JD, Rakic P, Torii M. Detection of local and remote cellular damage caused by spinal cord and peripheral nerve injury using a heat shock signaling reporter system. Ibro Reports. 5: 91-98. PMID 30480161 DOI: 10.1016/J.Ibror.2018.11.003  0.566
2018 Mis MA, Yang Y, Tanaka BS, Gomis-Perez C, Liu S, Dib-Hajj F, Adi T, Garcia-Milian R, Schulman BR, Dib-Hajj SD, Waxman SG. Resilience to Pain: A Peripheral Component Identified using induced Pluripotent Stem Cells and Dynamic Clamp. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30459225 DOI: 10.1523/Jneurosci.2433-18.2018  0.789
2018 Adi T, Estacion M, Schulman BR, Vernino S, Dib-Hajj S, Waxman S. [EXPRESS] A novel gain-of-function Na1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy. Molecular Pain. 1744806918815007. PMID 30392441 DOI: 10.1177/1744806918815007  0.432
2018 Hoffstaetter LJ, Mastrotto M, Merriman DK, Dib-Hajj SD, Waxman SG, Bagriantsev SN, Gracheva EO. Somatosensory Neurons Enter a State of Altered Excitability during Hibernation. Current Biology : Cb. PMID 30174191 DOI: 10.1016/J.Cub.2018.07.020  0.377
2018 Han C, Themistocleous AC, Estacion M, Dib-Hajj FB, Blesneac I, Macala L, Fratter C, Bennett DL, Waxman SG, Dib-Hajj SD. The novel activity of carbamazepine as an activation modulator extends from NaV1.7 mutations to the NaV1.8-S242T mutant channel from a patient with painful diabetic neuropathy. Molecular Pharmacology. PMID 30135145 DOI: 10.1124/mol.118.113076  0.417
2018 Guo Y, Benson C, Hill M, Henry S, Effraim P, Waxman S, Dib-Hajj S, Tan AM. [EXPRESS] THERAPEUTIC POTENTIAL OF PAK1 INHIBITION FOR PAIN ASSOCIATED WITH CUTANEOUS BURN INJURY. Molecular Pain. 1744806918788648. PMID 29956587 DOI: 10.1177/1744806918788648  0.707
2018 Mis MA, Rogers MF, Jeffries AR, Wilbrey AL, Chen L, Yang Y, Dib-Hajj S, Waxman SG, Stevens EB, Randall AD. Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons. Aging Cell. e12795. PMID 29943484 DOI: 10.1111/acel.12795  0.356
2018 Li Y, Zhu T, Yang H, Dib-Hajj S, Waxman S, Yu Y, Xu TL, Cheng X. [EXPRESS] Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner. Molecular Pain. 1744806918782229. PMID 29790812 DOI: 10.1177/1744806918782229  0.375
2018 Chen L, Huang J, Zhao P, Persson AK, Dib-Hajj FB, Cheng X, Tan A, Waxman SG, Dib-Hajj SD. Conditional knockout of Na1.6 in adult mice ameliorates neuropathic pain. Scientific Reports. 8: 3845. PMID 29497094 DOI: 10.1038/S41598-018-22216-W  0.737
2018 Huang J, Mis MA, Tanaka B, Adi T, Estacion M, Liu S, Walker S, Dib-Hajj SD, Waxman SG. Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation. Scientific Reports. 8: 1811. PMID 29379075 DOI: 10.1038/S41598-018-20221-7  0.807
2018 Yang Y, Mis MA, Estacion M, Dib-Hajj SD, Waxman SG. NaV1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine. Trends in Pharmacological Sciences. PMID 29370938 DOI: 10.1016/j.tips.2017.11.010  0.381
2017 Tham SW, Li L, Effraim P, Waxman S. Between fire and ice: refractory hypothermia and warmth-induced pain in inherited erythromelalgia. Bmj Case Reports. 2017. PMID 28751508 DOI: 10.1136/bcr-2017-219486  0.391
2017 Yang Y, Adi T, Effraim P, Chen L, Dib-Hajj SD, Waxman SG. Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal-induced hyperexcitability of sensory neurons due to Nav1.7 mutation I234T. British Journal of Pharmacology. PMID 28658526 DOI: 10.1111/bph.13935  0.387
2017 Huang J, Vanoye CG, Cutts A, Goldberg YP, Dib-Hajj SD, Cohen CJ, Waxman SG, George AL. Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability. The Journal of Clinical Investigation. PMID 28530638 DOI: 10.1172/Jci92373  0.407
2017 Tanaka BS, Nguyen PT, Zhou EY, Yang Y, Yarov-Yarovoy V, Dib-Hajj SD, Waxman SG. Gain-of-Function Mutation of a Voltage-Gated Sodium Channel NaV1.7 Associated with Peripheral Pain and Impaired Limb Development. The Journal of Biological Chemistry. PMID 28381558 DOI: 10.1074/Jbc.M117.778779  0.801
2017 Cao XC, Pappalardo LW, Waxman SG, Tan AM. Dendritic spine dysgenesis in superficial dorsal horn sensory neurons after spinal cord injury. Molecular Pain. 13: 1744806916688016. PMID 28326929 DOI: 10.1177/1744806916688016  0.714
2017 Dib-Hajj SD, Geha P, Waxman SG. Sodium channels in pain disorders: pathophysiology and prospects for treatment. Pain. PMID 28240647 DOI: 10.1097/J.Pain.0000000000000854  0.363
2017 Kapetis D, Sassone J, Yang Y, Galbardi B, Xenakis MN, Westra RL, Szklarczyk R, Lindsey P, Faber CG, Gerrits M, Merkies IS, Dib-Hajj SD, Mantegazza M, Waxman SG, Lauria G, et al. Network topology of NaV1.7 mutations in sodium channel-related painful disorders. Bmc Systems Biology. 11: 28. PMID 28235406 DOI: 10.1186/S12918-016-0382-0  0.378
2017 Zakrzewska JM, Palmer J, Morisset V, Giblin GM, Obermann M, Ettlin DA, Cruccu G, Bendtsen L, Estacion M, Derjean D, Waxman SG, Layton G, Gunn K, Tate S. Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial. The Lancet. Neurology. PMID 28216232 DOI: 10.1016/S1474-4422(17)30005-4  0.306
2017 Torii M, Sasaki M, Chang YW, Ishii S, Waxman SG, Kocsis JD, Rakic P, Hashimoto-Torii K. Detection of vulnerable neurons damaged by environmental insults in utero. Proceedings of the National Academy of Sciences of the United States of America. PMID 28123061 DOI: 10.1073/Pnas.1620641114  0.514
2017 Asiedu MN, Han C, Dib-Hajj SD, Waxman SG, Price TJ, Dussor G. The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development. Plos One. 12: e0169882. PMID 28118359 DOI: 10.1371/Journal.Pone.0169882  0.373
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/Srep40883  0.351
2016 Lee SJ, Kim DH, Hahn SJ, Waxman SG, Choi JS. Mechanism of inhibition by chlorpromazine of the human pain threshold sodium channel, Nav1.7. Neuroscience Letters. PMID 28017662 DOI: 10.1016/j.neulet.2016.12.051  0.358
2016 Rolyan H, Liu S, Hoeijmakers JG, Faber CG, Merkies IS, Lauria G, Black JA, Waxman SG. A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels. Molecular Pain. 12. PMID 27821467 DOI: 10.1177/1744806916674472  0.398
2016 Duan G, Han C, Wang Q, Guo S, Zhang Y, Ying Y, Huang P, Zhang L, Macala L, Shah P, Zhang M, Li N, Dib-Hajj SD, Waxman SG, Zhang X. A SCN10A SNP biases human pain sensitivity. Molecular Pain. 12. PMID 27590072 DOI: 10.1177/1744806916666083  0.397
2016 Han C, Yang Y, Te Morsche RH, Drenth JP, Politei JM, Waxman SG, Dib-Hajj SD. Familial gain-of-function Nav1.9 mutation in a painful channelopathy. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27503742 DOI: 10.1136/jnnp-2016-313804  0.31
2016 Tanaka BS, Zhao P, Dib-Hajj FB, Morisset V, Tate S, Waxman SG, Dib-Hajj SD. A gain-of-function mutation in Nav1.6 in a case of trigeminal neuralgia. Molecular Medicine (Cambridge, Mass.). 22. PMID 27496104 DOI: 10.2119/Molmed.2016.00131  0.806
2016 Yang Y, Huang J, Mis MA, Estacion M, Macala L, Shah P, Schulman BR, Horton DB, Dib-Hajj SD, Waxman SG. Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7511-22. PMID 27413160 DOI: 10.1523/Jneurosci.0462-16.2016  0.436
2016 Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, et al. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia. Science Translational Medicine. 8: 335ra56. PMID 27099175 DOI: 10.1126/Scitranslmed.Aad7653  0.421
2016 Geha P, Yang Y, Estacion M, Schulman BR, Tokuno H, Apkarian AV, Dib-Hajj SD, Waxman SG. Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling. Jama Neurology. PMID 27088781 DOI: 10.1001/Jamaneurol.2016.0389  0.385
2016 Persson AK, Hoeijmakers JG, Estacion M, Black JA, Waxman SG. Sodium Channels, Mitochondria, and Axonal Degeneration in Peripheral Neuropathy. Trends in Molecular Medicine. PMID 27085813 DOI: 10.1016/j.molmed.2016.03.008  0.434
2016 Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, ... ... Waxman SG, et al. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. Plos One. 11: e0152405. PMID 27050761 DOI: 10.1371/Journal.Pone.0152405  0.391
2016 Zhao P, Hill M, Liu S, Chen L, Bangalore L, Waxman SG, Tan AM. Dendritic Spine Remodeling Following Early and Late Rac1-Inhibition after Spinal Cord Injury: Evidence for a Pain Biomarker. Journal of Neurophysiology. jn.01057.2015. PMID 26936986 DOI: 10.1152/jn.01057.2015  0.709
2016 McDonnell A, Schulman B, Ali Z, Dib-Hajj SD, Brock F, Cobain S, Mainka T, Vollert J, Tarabar S, Waxman SG. Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile. Brain : a Journal of Neurology. PMID 26920677 DOI: 10.1093/Brain/Aww007  0.327
2016 Pappalardo LW, Black JA, Waxman SG. Sodium channels in astroglia and microglia. Glia. PMID 26919466 DOI: 10.1002/glia.22967  0.387
2016 Han C, Huang J, Waxman SG. Sodium channel Nav1.8: Emerging links to human disease. Neurology. PMID 26747884 DOI: 10.1212/Wnl.0000000000002333  0.431
2015 Dib-Hajj SD, Black JA, Waxman SG. NaV1.9: a sodium channel linked to human pain. Nature Reviews. Neuroscience. 16: 511-9. PMID 26243570 DOI: 10.1038/nrn3977  0.408
2015 Estacion M, Vohra BP, Liu S, Hoeijmakers JG, Faber CG, Merkies IS, Lauria G, Black JA, Waxman SG. Ca2+ toxicity due to reverse Na+-Ca2+ exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutation. Journal of Neurophysiology. jn.00195.2015. PMID 26156380 DOI: 10.1152/jn.00195.2015  0.429
2015 Tan AM, Samad OA, Dib-Hajj SD, Waxman SG. Virus-Mediated Knockdown of Nav1.3 in Dorsal Root Ganglia of STZ-Induced Diabetic Rats Alleviates Tactile Allodynia. Molecular Medicine (Cambridge, Mass.). 21: 544-52. PMID 26101954 DOI: 10.2119/molmed.2015.00063  0.728
2015 Namer B, Ørstavik K, Schmidt R, Kleggetveit IP, Weidner C, Mørk C, Kvernebo MS, Kvernebo K, Salter H, Carr TH, Segerdahl M, Quiding H, Waxman SG, Handwerker HO, Torebjörk HE, et al. Specific changes in conduction velocity recovery cycles of single nociceptors in an erythromelalgia patient with the I848T gain-of-function mutation of NaV1.7. Pain. PMID 25993546 DOI: 10.1097/j.pain.0000000000000229  0.333
2015 Rice FL, Albrecht PJ, Wymer JP, Black JA, Merkies IS, Faber CG, Waxman SG. Sodium channel Nav1.7 in vascular myocytes, endothelium, and innervating axons in human skin. Molecular Pain. 11: 26. PMID 25957174 DOI: 10.1186/S12990-015-0024-3  0.381
2015 Akin EJ, Solé L, Dib-Hajj SD, Waxman SG, Tamkun MM. Preferential targeting of Nav1.6 voltage-gated Na+ Channels to the axon initial segment during development. Plos One. 10: e0124397. PMID 25874799 DOI: 10.1371/Journal.Pone.0124397  0.404
2015 Han C, Yang Y, de Greef BT, Hoeijmakers JG, Gerrits MM, Verhamme C, Qu J, Lauria G, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG. The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy. Neuromolecular Medicine. 17: 158-69. PMID 25791876 DOI: 10.1007/s12017-015-8347-9  0.418
2015 Han C, Estacion M, Huang J, Vasylyev D, Zhao P, Dib-Hajj SD, Waxman SG. Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons. Journal of Neurophysiology. 113: 3172-85. PMID 25787950 DOI: 10.1152/Jn.00113.2015  0.42
2015 Shields SD, Butt RP, Dib-Hajj SD, Waxman SG. Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosis. Plos One. 10: e0119067. PMID 25747279 DOI: 10.1371/Journal.Pone.0119067  0.707
2015 Blanchard MG, Willemsen MH, Walker JB, Dib-Hajj SD, Waxman SG, Jongmans MC, Kleefstra T, van de Warrenburg BP, Praamstra P, Nicolai J, Yntema HG, Bindels RJ, Meisler MH, Kamsteeg EJ. De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy. Journal of Medical Genetics. 52: 330-7. PMID 25725044 DOI: 10.1136/Jmedgenet-2014-102813  0.316
2015 Bandaru SP, Liu S, Waxman SG, Tan AM. Dendritic spine dysgenesis contributes to hyperreflexia after spinal cord injury. Journal of Neurophysiology. 113: 1598-615. PMID 25505110 DOI: 10.1152/jn.00566.2014  0.69
2015 Tan AM, Waxman SG. Dendritic spine dysgenesis in neuropathic pain. Neuroscience Letters. 601: 54-60. PMID 25445354 DOI: 10.1016/j.neulet.2014.11.024  0.706
2014 Waxman SG, Merkies IS, Gerrits MM, Dib-Hajj SD, Lauria G, Cox JJ, Wood JN, Woods CG, Drenth JP, Faber CG. Sodium channel genes in pain-related disorders: phenotype-genotype associations and recommendations for clinical use. The Lancet. Neurology. 13: 1152-60. PMID 25316021 DOI: 10.1016/S1474-4422(14)70150-4  0.368
2014 Huang J, Yang Y, Dib-Hajj SD, van Es M, Zhao P, Salomon J, Drenth JP, Waxman SG. Depolarized inactivation overcomes impaired activation to produce DRG neuron hyperexcitability in a Nav1.7 mutation in a patient with distal limb pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12328-40. PMID 25209274 DOI: 10.1523/Jneurosci.2773-14.2014  0.432
2014 Pappalardo LW, Liu S, Black JA, Waxman SG. Dynamics of sodium channel Nav1.5 expression in astrocytes in mouse models of multiple sclerosis. Neuroreport. 25: 1208-15. PMID 25144393 DOI: 10.1097/WNR.0000000000000249  0.376
2014 Lauria G, Ziegler D, Malik R, Merkies IS, Waxman SG, Faber CG. The role of sodium channels in painful diabetic and idiopathic neuropathy. Current Diabetes Reports. 14: 538. PMID 25142720 DOI: 10.1007/s11892-014-0538-5  0.362
2014 Persson AK, Estacion M, Ahn H, Liu S, Stamboulian-Platel S, Waxman SG, Black JA. Contribution of sodium channels to lamellipodial protrusion and Rac1 and ERK1/2 activation in ATP-stimulated microglia. Glia. 62: 2080-95. PMID 25043721 DOI: 10.1002/glia.22728  0.353
2014 Estacion M, O'Brien JE, Conravey A, Hammer MF, Waxman SG, Dib-Hajj SD, Meisler MH. A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy. Neurobiology of Disease. 69: 117-23. PMID 24874546 DOI: 10.1016/J.Nbd.2014.05.017  0.358
2014 Huang J, Han C, Estacion M, Vasylyev D, Hoeijmakers JG, Gerrits MM, Tyrrell L, Lauria G, Faber CG, Dib-Hajj SD, Merkies IS, Waxman SG. Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy. Brain : a Journal of Neurology. 137: 1627-42. PMID 24776970 DOI: 10.1093/Brain/Awu079  0.435
2014 Mishra AM, Bai X, Sanganahalli BG, Waxman SG, Shatillo O, Grohn O, Hyder F, Pitkänen A, Blumenfeld H. Decreased resting functional connectivity after traumatic brain injury in the rat. Plos One. 9: e95280. PMID 24748279 DOI: 10.1371/Journal.Pone.0095280  0.521
2014 Pappalardo LW, Samad OA, Black JA, Waxman SG. Voltage-gated sodium channel Nav 1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na+ /Ca2+ exchange. Glia. 62: 1162-75. PMID 24740847 DOI: 10.1002/glia.22671  0.363
2014 Lampert A, Eberhardt M, Waxman SG. Altered sodium channel gating as molecular basis for pain: contribution of activation, inactivation, and resurgent currents. Handbook of Experimental Pharmacology. 221: 91-110. PMID 24737233 DOI: 10.1007/978-3-642-41588-3_5  0.621
2014 Liu S, Zwinger P, Black JA, Waxman SG. Tapered withdrawal of phenytoin removes protective effect in EAE without inflammatory rebound and mortality. Journal of the Neurological Sciences. 341: 8-12. PMID 24690348 DOI: 10.1016/j.jns.2014.03.029  0.341
2014 Oliva MK, McGarr TC, Beyer BJ, Gazina E, Kaplan DI, Cordeiro L, Thomas E, Dib-Hajj SD, Waxman SG, Frankel WN, Petrou S. Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy. Neurobiology of Disease. 67: 180-90. PMID 24657915 DOI: 10.1016/j.nbd.2014.03.007  0.352
2014 Black JA, Vasylyev D, Dib-Hajj SD, Waxman SG. Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus. Experimental Neurology. 253: 174-9. PMID 24424281 DOI: 10.1016/j.expneurol.2014.01.004  0.444
2014 Vasylyev DV, Han C, Zhao P, Dib-Hajj S, Waxman SG. Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H. Journal of Neurophysiology. 111: 1429-43. PMID 24401712 DOI: 10.1152/jn.00763.2013  0.439
2013 Samad OA, Tan AM, Cheng X, Foster E, Dib-Hajj SD, Waxman SG. Virus-mediated shRNA Knockdown of Nav1.3 in Rat Dorsal Root Ganglion Attenuates Nerve Injury-induced Neuropathic Pain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 49-56. PMID 28178604 DOI: 10.1038/mt.2012.169  0.707
2013 Persson AK, Kim I, Zhao P, Estacion M, Black JA, Waxman SG. Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19250-61. PMID 24305821 DOI: 10.1523/JNEUROSCI.2148-13.2013  0.399
2013 Ommaya AK, Adams KM, Allman RM, Collins EG, Cooper RA, Dixon CE, Fishman PS, Henry JA, Kardon R, Kerns RD, Kupersmith J, Lo A, Macko R, McArdle R, McGlinchey RE, ... ... Waxman SG, et al. Guest editorial: Opportunities in rehabilitation research. Journal of Rehabilitation Research and Development. 50: vii-xxxii. PMID 24203548 DOI: 10.1682/Jrrd.2012.09.0167  0.319
2013 Bird EV, Christmas CR, Loescher AR, Smith KG, Robinson PP, Black JA, Waxman SG, Boissonade FM. Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas. Molecular Pain. 9: 52. PMID 24144460 DOI: 10.1186/1744-8069-9-52  0.418
2013 Black JA, Waxman SG. Noncanonical roles of voltage-gated sodium channels. Neuron. 80: 280-91. PMID 24139034 DOI: 10.1016/j.neuron.2013.09.012  0.399
2013 Yang Y, Vasylyev DV, Dib-Hajj F, Veeramah KR, Hammer MF, Dib-Hajj SD, Waxman SG. Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10.2-R327H demonstrate the role of this residue in stabilizing the channel closed state. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16586-93. PMID 24133262 DOI: 10.1523/JNEUROSCI.2307-13.2013  0.342
2013 Huang J, Yang Y, Zhao P, Gerrits MM, Hoeijmakers JG, Bekelaar K, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG. Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14087-97. PMID 23986244 DOI: 10.1523/Jneurosci.2710-13.2013  0.441
2013 Tan AM, Samad OA, Liu S, Bandaru S, Zhao P, Waxman SG. Burn injury-induced mechanical allodynia is maintained by Rac1-regulated dendritic spine dysgenesis. Experimental Neurology. 248: 509-19. PMID 23933578 DOI: 10.1016/j.expneurol.2013.07.017  0.713
2013 Black JA, Hoeijmakers JG, Faber CG, Merkies IS, Waxman SG. NaV1.7: stress-induced changes in immunoreactivity within magnocellular neurosecretory neurons of the supraoptic nucleus. Molecular Pain. 9: 39. PMID 23924059 DOI: 10.1186/1744-8069-9-39  0.377
2013 Andres C, Hasenauer J, Ahn HS, Joseph EK, Isensee J, Theis FJ, Allgöwer F, Levine JD, Dib-Hajj SD, Waxman SG, Hucho T. Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia. Pain. 154: 2216-26. PMID 23867734 DOI: 10.1016/j.pain.2013.07.005  0.368
2013 Yang Y, Estacion M, Dib-Hajj SD, Waxman SG. Molecular architecture of a sodium channel S6 helix: radial tuning of the voltage-gated sodium channel 1.7 activation gate. The Journal of Biological Chemistry. 288: 13741-7. PMID 23536180 DOI: 10.1074/jbc.M113.462366  0.359
2013 Estacion M, Yang Y, Dib-Hajj SD, Tyrrell L, Lin Z, Yang Y, Waxman SG. A new Nav1.7 mutation in an erythromelalgia patient. Biochemical and Biophysical Research Communications. 432: 99-104. PMID 23376079 DOI: 10.1016/j.bbrc.2013.01.079  0.352
2013 Persson AK, Liu S, Faber CG, Merkies IS, Black JA, Waxman SG. Neuropathy-associated Nav1.7 variant I228M impairs integrity of dorsal root ganglion neuron axons. Annals of Neurology. 73: 140-5. PMID 23280954 DOI: 10.1002/ana.23725  0.458
2013 Dib-Hajj SD, Yang Y, Black JA, Waxman SG. The Na(V)1.7 sodium channel: from molecule to man. Nature Reviews. Neuroscience. 14: 49-62. PMID 23232607 DOI: 10.1038/nrn3404  0.443
2013 Black JA, Newcombe J, Waxman SG. Nav1.5 sodium channels in macrophages in multiple sclerosis lesions. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 532-42. PMID 22951351 DOI: 10.1177/1352458512460417  0.304
2013 Samad OA, Tan AM, Cheng X, Foster E, Dib-Hajj SD, Waxman SG. Virus-mediated shRNA knockdown of Na(v)1.3 in rat dorsal root ganglion attenuates nerve injury-induced neuropathic pain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 49-56. PMID 22910296 DOI: 10.1038/mt.2012.169  0.734
2012 Yang Y, Dib-Hajj SD, Zhang J, Zhang Y, Tyrrell L, Estacion M, Waxman SG. Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel. Nature Communications. 3: 1186. PMID 23149731 DOI: 10.1038/Ncomms2184  0.4
2012 Black JA, Frézel N, Dib-Hajj SD, Waxman SG. Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn. Molecular Pain. 8: 82. PMID 23134641 DOI: 10.1186/1744-8069-8-82  0.439
2012 Faber CG, Lauria G, Merkies IS, Cheng X, Han C, Ahn HS, Persson AK, Hoeijmakers JG, Gerrits MM, Pierro T, Lombardi R, Kapetis D, Dib-Hajj SD, Waxman SG. Gain-of-function Nav1.8 mutations in painful neuropathy. Proceedings of the National Academy of Sciences of the United States of America. 109: 19444-9. PMID 23115331 DOI: 10.1073/pnas.1216080109  0.43
2012 Shields SD, Cheng X, Uçeyler N, Sommer C, Dib-Hajj SD, Waxman SG. Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10819-32. PMID 22875917 DOI: 10.1523/Jneurosci.0304-12.2012  0.765
2012 Han C, Hoeijmakers JG, Liu S, Gerrits MM, te Morsche RH, Lauria G, Dib-Hajj SD, Drenth JP, Faber CG, Merkies IS, Waxman SG. Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy. Brain : a Journal of Neurology. 135: 2613-28. PMID 22826602 DOI: 10.1093/brain/aws187  0.434
2012 Shields SD, Ahn HS, Yang Y, Han C, Seal RP, Wood JN, Waxman SG, Dib-Hajj SD. Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain. 153: 2017-30. PMID 22703890 DOI: 10.1016/J.Pain.2012.04.022  0.765
2012 Gasser A, Ho TS, Cheng X, Chang KJ, Waxman SG, Rasband MN, Dib-Hajj SD. An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of Ranvier. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7232-43. PMID 22623668 DOI: 10.1523/Jneurosci.5434-11.2012  0.405
2012 Tan AM, Samad OA, Fischer TZ, Zhao P, Persson AK, Waxman SG. Maladaptive dendritic spine remodeling contributes to diabetic neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6795-807. PMID 22593049 DOI: 10.1523/JNEUROSCI.1017-12.2012  0.702
2012 Hughes JP, Chessell I, Malamut R, Perkins M, Bačkonja M, Baron R, Farrar JT, Field MJ, Gereau RW, Gilron I, McMahon SB, Porreca F, Rappaport BA, Rice F, Richman LK, ... ... Waxman SG, et al. Understanding chronic inflammatory and neuropathic pain. Annals of the New York Academy of Sciences. 1255: 30-44. PMID 22564068 DOI: 10.1111/J.1749-6632.2012.06561.X  0.587
2012 Han C, Hoeijmakers JG, Ahn HS, Zhao P, Shah P, Lauria G, Gerrits MM, te Morsche RH, Dib-Hajj SD, Drenth JP, Faber CG, Merkies IS, Waxman SG. Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability. Neurology. 78: 1635-43. PMID 22539570 DOI: 10.1212/WNL.0b013e3182574f12  0.454
2012 O'Brien JE, Sharkey LM, Vallianatos CN, Han C, Blossom JC, Yu T, Waxman SG, Dib-Hajj SD, Meisler MH. Interaction of voltage-gated sodium channel Nav1.6 (SCN8A) with microtubule-associated protein Map1b. The Journal of Biological Chemistry. 287: 18459-66. PMID 22474336 DOI: 10.1074/jbc.M111.336024  0.378
2012 Baker MD, Waxman SG. Sodium channel slow inactivation and adaptation in C-fibres. The Journal of Physiology. 590: 1513-4. PMID 22467918 DOI: 10.1113/jphysiol.2011.224436  0.403
2012 Honmou O, Onodera R, Sasaki M, Waxman SG, Kocsis JD. Mesenchymal stem cells: therapeutic outlook for stroke. Trends in Molecular Medicine. 18: 292-7. PMID 22459358 DOI: 10.1016/j.molmed.2012.02.003  0.494
2012 Wu DF, Chandra D, McMahon T, Wang D, Dadgar J, Kharazia VN, Liang YJ, Waxman SG, Dib-Hajj SD, Messing RO. PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice. The Journal of Clinical Investigation. 122: 1306-15. PMID 22426212 DOI: 10.1172/JCI61934  0.374
2012 Shields SD, Cheng X, Gasser A, Saab CY, Tyrrell L, Eastman EM, Iwata M, Zwinger PJ, Black JA, Dib-Hajj SD, Waxman SG. A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis. Annals of Neurology. 71: 186-94. PMID 22367990 DOI: 10.1002/Ana.22665  0.725
2012 Veeramah KR, O'Brien JE, Meisler MH, Cheng X, Dib-Hajj SD, Waxman SG, Talwar D, Girirajan S, Eichler EE, Restifo LL, Erickson RP, Hammer MF. De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP. American Journal of Human Genetics. 90: 502-10. PMID 22365152 DOI: 10.1016/J.Ajhg.2012.01.006  0.345
2012 Black JA, Waxman SG. Sodium channels and microglial function. Experimental Neurology. 234: 302-15. PMID 21985863 DOI: 10.1016/j.expneurol.2011.09.030  0.376
2012 Tan AM, Waxman SG. Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms. Experimental Neurology. 235: 142-51. PMID 21925174 DOI: 10.1016/j.expneurol.2011.08.026  0.708
2012 Faber CG, Hoeijmakers JG, Ahn HS, Cheng X, Han C, Choi JS, Estacion M, Lauria G, Vanhoutte EK, Gerrits MM, Dib-Hajj S, Drenth JP, Waxman SG, Merkies IS. Gain of function Naν1.7 mutations in idiopathic small fiber neuropathy. Annals of Neurology. 71: 26-39. PMID 21698661 DOI: 10.1002/ana.22485  0.391
2012 Akin EJ, Weigel AV, Dib-Hajj SD, Waxman SG, Krapf D, Tamkun MM. Analysis of Voltage-Gated Sodium Channel Membrane Dynamics in Hippocampal Neurons via a Fluorescent Protein and Biotin Tagged Nav1.6 Channel Biophysical Journal. 102: 528a. DOI: 10.1016/J.Bpj.2011.11.2884  0.394
2011 Estacion M, Han C, Choi JS, Hoeijmakers JG, Lauria G, Drenth JP, Gerrits MM, Dib-Hajj SD, Faber CG, Merkies IS, Waxman SG. Intra- and interfamily phenotypic diversity in pain syndromes associated with a gain-of-function variant of NaV1.7. Molecular Pain. 7: 92. PMID 22136189 DOI: 10.1186/1744-8069-7-92  0.405
2011 Shields SD, Waxman SG. Cerebellar dysfunction in multiple sclerosis: in the blink of an eye. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 1152-4. PMID 21980147 DOI: 10.1177/1352458511410345  0.707
2011 Tan AM, Chang YW, Zhao P, Hains BC, Waxman SG. Rac1-regulated dendritic spine remodeling contributes to neuropathic pain after peripheral nerve injury. Experimental Neurology. 232: 222-33. PMID 21963650 DOI: 10.1016/j.expneurol.2011.08.028  0.814
2011 Choi JS, Waxman SG. Physiological interactions between Na(v)1.7 and Na(v)1.8 sodium channels: a computer simulation study. Journal of Neurophysiology. 106: 3173-84. PMID 21940606 DOI: 10.1152/jn.00100.2011  0.358
2011 Cheng X, Dib-Hajj SD, Tyrrell L, Te Morsche RH, Drenth JP, Waxman SG. Deletion mutation of sodium channel Na(V)1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability. Brain : a Journal of Neurology. 134: 1972-86. PMID 21705421 DOI: 10.1093/brain/awr143  0.376
2011 Persson AK, Gasser A, Black JA, Waxman SG. Nav1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas. Experimental Neurology. 230: 273-9. PMID 21601570 DOI: 10.1016/j.expneurol.2011.05.005  0.424
2011 Ahn HS, Black JA, Zhao P, Tyrrell L, Waxman SG, Dib-Hajj SD. Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons. Molecular Pain. 7: 32. PMID 21569247 DOI: 10.1186/1744-8069-7-32  0.432
2011 Honmou O, Houkin K, Matsunaga T, Niitsu Y, Ishiai S, Onodera R, Waxman SG, Kocsis JD. Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke. Brain : a Journal of Neurology. 134: 1790-807. PMID 21493695 DOI: 10.1093/brain/awr063  0.478
2011 Gurkiewicz M, Korngreen A, Waxman SG, Lampert A. Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation. Journal of Neurophysiology. 105: 1546-57. PMID 21289137 DOI: 10.1152/Jn.00703.2010  0.806
2011 Choi JS, Boralevi F, Brissaud O, Sánchez-Martín J, Te Morsche RH, Dib-Hajj SD, Drenth JP, Waxman SG. Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons. Nature Reviews. Neurology. 7: 51-5. PMID 21079636 DOI: 10.1038/nrneurol.2010.162  0.375
2010 Persson AK, Black JA, Gasser A, Cheng X, Fischer TZ, Waxman SG. Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals. Molecular Pain. 6: 84. PMID 21118538 DOI: 10.1186/1744-8069-6-84  0.398
2010 Wilkins A, Kondo Y, Song J, Liu S, Compston A, Black JA, Waxman SG, Duncan ID. Slowly progressive axonal degeneration in a rat model of chronic, nonimmune-mediated demyelination. Journal of Neuropathology and Experimental Neurology. 69: 1256-69. PMID 21107138 DOI: 10.1097/Nen.0B013E3181Ffc317  0.334
2010 Nikolajsen L, Black JA, Kroner K, Jensen TS, Waxman SG. Neuroma removal for neuropathic pain: efficacy and predictive value of lidocaine infusion. The Clinical Journal of Pain. 26: 788-93. PMID 20973154 DOI: 10.1097/AJP.0b013e3181ed0823  0.36
2010 Gasser A, Cheng X, Gilmore ES, Tyrrell L, Waxman SG, Dib-Hajj SD. Two Nedd4-binding motifs underlie modulation of sodium channel Nav1.6 by p38 MAPK. The Journal of Biological Chemistry. 285: 26149-61. PMID 20530479 DOI: 10.1074/jbc.M109.098681  0.374
2010 Choi JS, Cheng X, Foster E, Leffler A, Tyrrell L, Te Morsche RH, Eastman EM, Jansen HJ, Huehne K, Nau C, Dib-Hajj SD, Drenth JP, Waxman SG. Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia. Brain : a Journal of Neurology. 133: 1823-35. PMID 20478850 DOI: 10.1093/brain/awq114  0.427
2010 Cheng X, Dib-Hajj SD, Tyrrell L, Wright DA, Fischer TZ, Waxman SG. Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders. Molecular Pain. 6: 24. PMID 20429905 DOI: 10.1186/1744-8069-6-24  0.377
2010 Estacion M, Gasser A, Dib-Hajj SD, Waxman SG. A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons. Experimental Neurology. 224: 362-8. PMID 20420834 DOI: 10.1016/j.expneurol.2010.04.012  0.386
2010 Ahn HS, Dib-Hajj SD, Cox JJ, Tyrrell L, Elmslie FV, Clarke AA, Drenth JP, Woods CG, Waxman SG. A new Nav1.7 sodium channel mutation I234T in a child with severe pain. European Journal of Pain (London, England). 14: 944-50. PMID 20385509 DOI: 10.1016/j.ejpain.2010.03.007  0.372
2010 Kullmann DM, Waxman SG. Neurological channelopathies: new insights into disease mechanisms and ion channel function. The Journal of Physiology. 588: 1823-7. PMID 20375141 DOI: 10.1113/jphysiol.2010.190652  0.325
2010 Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. Sodium channels in normal and pathological pain. Annual Review of Neuroscience. 33: 325-47. PMID 20367448 DOI: 10.1146/Annurev-Neuro-060909-153234  0.635
2010 Black JA, Newcombe J, Waxman SG. Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5. Brain : a Journal of Neurology. 133: 835-46. PMID 20147455 DOI: 10.1093/brain/awq003  0.371
2010 Stamboulian S, Choi JS, Ahn HS, Chang YW, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD. ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1637-47. PMID 20130174 DOI: 10.1523/JNEUROSCI.4872-09.2010  0.414
2010 Chang YW, Tan A, Saab C, Waxman S. Unilateral focal burn injury is followed by long-lasting bilateral allodynia and neuronal hyperexcitability in spinal cord dorsal horn. The Journal of Pain : Official Journal of the American Pain Society. 11: 119-30. PMID 19744891 DOI: 10.1016/J.Jpain.2009.06.009  0.714
2009 Estacion M, Harty TP, Choi JS, Tyrrell L, Dib-Hajj SD, Waxman SG. A sodium channel gene SCN9A polymorphism that increases nociceptor excitability. Annals of Neurology. 66: 862-6. PMID 20033988 DOI: 10.1002/ana.21895  0.397
2009 Dib-Hajj SD, Black JA, Waxman SG. Voltage-gated sodium channels: therapeutic targets for pain. Pain Medicine (Malden, Mass.). 10: 1260-9. PMID 19818036 DOI: 10.1111/j.1526-4637.2009.00719.x  0.427
2009 Lampert A, Dib-Hajj SD, Eastman EM, Tyrrell L, Lin Z, Yang Y, Waxman SG. Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials. Biochemical and Biophysical Research Communications. 390: 319-24. PMID 19800314 DOI: 10.1016/j.bbrc.2009.09.121  0.609
2009 Tan AM, Choi JS, Waxman SG, Hains BC. Dendritic spine remodeling after spinal cord injury alters neuronal signal processing. Journal of Neurophysiology. 102: 2396-409. PMID 19692517 DOI: 10.1152/jn.00095.2009  0.805
2009 Dib-Hajj SD, Choi JS, Macala LJ, Tyrrell L, Black JA, Cummins TR, Waxman SG. Transfection of rat or mouse neurons by biolistics or electroporation. Nature Protocols. 4: 1118-26. PMID 19617884 DOI: 10.1038/Nprot.2009.90  0.627
2009 Cummins TR, Rush AM, Estacion M, Dib-Hajj SD, Waxman SG. Voltage-clamp and current-clamp recordings from mammalian DRG neurons. Nature Protocols. 4: 1103-12. PMID 19617882 DOI: 10.1038/Nprot.2009.91  0.544
2009 Tan AM, Zhao P, Waxman SG, Hains BC. Early microglial inhibition preemptively mitigates chronic pain development after experimental spinal cord injury. Journal of Rehabilitation Research and Development. 46: 123-33. PMID 19533525  0.802
2009 Laezza F, Lampert A, Kozel MA, Gerber BR, Rush AM, Nerbonne JM, Waxman SG, Dib-Hajj SD, Ornitz DM. FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels. Molecular and Cellular Neurosciences. 42: 90-101. PMID 19465131 DOI: 10.1016/J.Mcn.2009.05.007  0.601
2009 Han C, Dib-Hajj SD, Lin Z, Li Y, Eastman EM, Tyrrell L, Cao X, Yang Y, Waxman SG. Early- and late-onset inherited erythromelalgia: genotype-phenotype correlation. Brain : a Journal of Neurology. 132: 1711-22. PMID 19369487 DOI: 10.1093/brain/awp078  0.384
2009 Fischer TZ, Tan AM, Waxman SG. Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain. Brain Research. 1268: 154-61. PMID 19285053 DOI: 10.1016/j.brainres.2009.02.063  0.709
2009 Sharkey LM, Cheng X, Drews V, Buchner DA, Jones JM, Justice MJ, Waxman SG, Dib-Hajj SD, Meisler MH. The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2733-41. PMID 19261867 DOI: 10.1523/Jneurosci.6026-08.2009  0.365
2009 Choi JS, Zhang L, Dib-Hajj SD, Han C, Tyrrell L, Lin Z, Wang X, Yang Y, Waxman SG. Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off. Experimental Neurology. 216: 383-9. PMID 19162012 DOI: 10.1016/j.expneurol.2008.12.012  0.407
2009 Carrithers MD, Chatterjee G, Carrithers LM, Offoha R, Iheagwara U, Rahner C, Graham M, Waxman SG. Regulation of podosome formation in macrophages by a splice variant of the sodium channel SCN8A. The Journal of Biological Chemistry. 284: 8114-26. PMID 19136557 DOI: 10.1074/jbc.M801892200  0.339
2009 Black JA, Liu S, Waxman SG. Sodium channel activity modulates multiple functions in microglia. Glia. 57: 1072-81. PMID 19115387 DOI: 10.1002/glia.20830  0.332
2009 Blumenfeld H, Lampert A, Klein JP, Mission J, Chen MC, Rivera M, Dib-Hajj S, Brennan AR, Hains BC, Waxman SG. Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis. Epilepsia. 50: 44-55. PMID 18637833 DOI: 10.1111/J.1528-1167.2008.01710.X  0.811
2009 Stys PK, Ransom BR, Black JA, Waxman SG. Anoxic/ischemic injury in axons The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0024  0.734
2009 Waxman SG, Kocsis JD, Black JA. Pathophysiology of demyelinated axons The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0023  0.472
2009 Stys PK, Waxman SG, Ransom BR. Ion pumps and exchangers The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0015  0.695
2009 Waxman SG, Kocsis JD, Stys PK. The Axon: Structure, Function and Pathophysiology The Axon: Structure, Function and Pathophysiology. 1-708. DOI: 10.1093/acprof:oso/9780195082937.001.0001  0.63
2008 Dib-Hajj SD, Yang Y, Waxman SG. Genetics and molecular pathophysiology of Na(v)1.7-related pain syndromes. Advances in Genetics. 63: 85-110. PMID 19185186 DOI: 10.1016/S0065-2660(08)01004-3  0.434
2008 Black JA, Nikolajsen L, Kroner K, Jensen TS, Waxman SG. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas. Annals of Neurology. 64: 644-53. PMID 19107992 DOI: 10.1002/ana.21527  0.408
2008 Tan AM, Stamboulian S, Chang YW, Zhao P, Hains AB, Waxman SG, Hains BC. Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13173-83. PMID 19052208 DOI: 10.1523/JNEUROSCI.3142-08.2008  0.81
2008 Dib-Hajj SD, Estacion M, Jarecki BW, Tyrrell L, Fischer TZ, Lawden M, Cummins TR, Waxman SG. Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable. Molecular Pain. 4: 37. PMID 18803825 DOI: 10.1186/1744-8069-4-37  0.776
2008 Lampert A, O'Reilly AO, Dib-Hajj SD, Tyrrell L, Wallace BA, Waxman SG. A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation. The Journal of Biological Chemistry. 283: 24118-27. PMID 18550534 DOI: 10.1074/jbc.M802900200  0.609
2008 Saab CY, Waxman SG, Hains BC. Alarm or curse? The pain of neuroinflammation. Brain Research Reviews. 58: 226-35. PMID 18486228 DOI: 10.1016/J.Brainresrev.2008.04.002  0.807
2008 Black JA, Waxman SG. Phenytoin protects central axons in experimental autoimmune encephalomyelitis. Journal of the Neurological Sciences. 274: 57-63. PMID 18485368 DOI: 10.1016/j.jns.2008.04.001  0.381
2008 Zhao P, Barr TP, Hou Q, Dib-Hajj SD, Black JA, Albrecht PJ, Petersen K, Eisenberg E, Wymer JP, Rice FL, Waxman SG. Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain. Pain. 139: 90-105. PMID 18442883 DOI: 10.1016/J.Pain.2008.03.016  0.421
2008 Deumens R, Joosten EA, Waxman SG, Hains BC. Locomotor dysfunction and pain: the scylla and charybdis of fiber sprouting after spinal cord injury. Molecular Neurobiology. 37: 52-63. PMID 18415034 DOI: 10.1007/s12035-008-8016-1  0.776
2008 Hudmon A, Choi JS, Tyrrell L, Black JA, Rush AM, Waxman SG, Dib-Hajj SD. Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3190-201. PMID 18354022 DOI: 10.1523/Jneurosci.4403-07.2008  0.428
2008 Shaw SK, Owolabi SA, Bagley J, Morin N, Cheng E, LeBlanc BW, Kim M, Harty P, Waxman SG, Saab CY. Activated polymorphonuclear cells promote injury and excitability of dorsal root ganglia neurons. Experimental Neurology. 210: 286-94. PMID 18201702 DOI: 10.1016/J.Expneurol.2007.11.024  0.394
2008 Cheng X, Dib-Hajj SD, Tyrrell L, Waxman SG. Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade. Molecular Pain. 4: 1. PMID 18171466 DOI: 10.1186/1744-8069-4-1  0.372
2008 Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, ... ... Waxman SG, et al. Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia. 49: 400-9. PMID 18070091 DOI: 10.1111/J.1528-1167.2007.01458.X  0.612
2008 Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC. Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response. Molecular Pharmacology. 73: 243-51. PMID 17959714 DOI: 10.1124/Mol.107.039594  0.78
2008 Dib-Hajj SD, Hains BC, Black JA, Waxman SG. Voltage-Gated Sodium Channels: Multiple Roles in the Pathophysiology of Pain Structure, Function, and Modulation of Neuronal Voltagegated Ion Channels. 67-104. DOI: 10.1002/9780470429907.ch3  0.803
2007 Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. From genes to pain: Na v 1.7 and human pain disorders. Trends in Neurosciences. 30: 555-63. PMID 17950472 DOI: 10.1016/J.Tins.2007.08.004  0.646
2007 Black JA, Newcombe J, Trapp BD, Waxman SG. Sodium channel expression within chronic multiple sclerosis plaques. Journal of Neuropathology and Experimental Neurology. 66: 828-37. PMID 17805013 DOI: 10.1097/nen.0b013e3181462841  0.341
2007 Cummins TR, Sheets PL, Waxman SG. The roles of sodium channels in nociception: Implications for mechanisms of pain. Pain. 131: 243-57. PMID 17766042 DOI: 10.1016/J.Pain.2007.07.026  0.814
2007 Zhao P, Waxman SG, Hains BC. Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8893-902. PMID 17699671 DOI: 10.1523/JNEUROSCI.2209-07.2007  0.812
2007 Black JA, Liu S, Carrithers M, Carrithers LM, Waxman SG. Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine. Annals of Neurology. 62: 21-33. PMID 17654737 DOI: 10.1002/ana.21172  0.365
2007 Kocsis JD, Waxman SG. Schwann cells and their precursors for repair of central nervous system myelin. Brain : a Journal of Neurology. 130: 1978-80. PMID 17626033 DOI: 10.1093/brain/awm161  0.536
2007 Hains BC, Waxman SG. Sodium channel expression and the molecular pathophysiology of pain after SCI. Progress in Brain Research. 161: 195-203. PMID 17618978 DOI: 10.1016/S0079-6123(06)61013-3  0.776
2007 Sheets PL, Jackson JO, Waxman SG, Dib-Hajj SD, Cummins TR. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity. The Journal of Physiology. 581: 1019-31. PMID 17430993 DOI: 10.1113/Jphysiol.2006.127027  0.789
2007 Woolfe F, Waxman SG, Hains BC. In silico modeling of axonal reconnection within a discrete fiber tract after spinal cord injury. Journal of Neurotrauma. 24: 421-32. PMID 17376004 DOI: 10.1089/neu.2006.0131  0.776
2007 Zhao P, Waxman SG, Hains BC. Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2357-68. PMID 17329433 DOI: 10.1523/JNEUROSCI.0138-07.2007  0.81
2007 Han C, Lampert A, Rush AM, Dib-Hajj SD, Wang X, Yang Y, Waxman SG. Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7. Molecular Pain. 3: 3. PMID 17239250 DOI: 10.1186/1744-8069-3-3  0.64
2007 Rush AM, Cummins TR, Waxman SG. Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons. The Journal of Physiology. 579: 1-14. PMID 17158175 DOI: 10.1113/Jphysiol.2006.121483  0.544
2007 Hudmon A, Choi J, Tyrrell L, Black J, Rush A, Waxman S, Dib-Hajj S. 46 PHOSPHORYLATION OF SODIUM CHANNEL NAV1.8 BY P38 MAPK INCREASES CURRENT DENSITY IN DRG NEURONS European Journal of Pain. 11: S19-S19. DOI: 10.1016/j.ejpain.2007.03.060  0.376
2007 Harel NY, Yang YS, Strittmatter SM, Kocsis JD, Waxman SG. The Dawn of Molecular and Cellular Therapies for Traumatic Spinal Cord Injury Molecular Neurology. 207-220. DOI: 10.1016/B978-012369509-3.50016-0  0.454
2006 Harty TP, Dib-Hajj SD, Tyrrell L, Blackman R, Hisama FM, Rose JB, Waxman SG. Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12566-75. PMID 17135418 DOI: 10.1523/Jneurosci.3424-06.2006  0.436
2006 Lampert A, Dib-Hajj SD, Tyrrell L, Waxman SG. Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating. The Journal of Biological Chemistry. 281: 36029-35. PMID 17008310 DOI: 10.1074/jbc.M607637200  0.631
2006 Black JA, Liu S, Hains BC, Saab CY, Waxman SG. Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE. Brain : a Journal of Neurology. 129: 3196-208. PMID 16931536 DOI: 10.1093/Brain/Awl216  0.798
2006 Zhao P, Waxman SG, Hains BC. Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury. Molecular Pain. 2: 27. PMID 16916452 DOI: 10.1186/1744-8069-2-27  0.832
2006 Rush AM, Wittmack EK, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily. The European Journal of Neuroscience. 23: 2551-62. PMID 16817858 DOI: 10.1111/J.1460-9568.2006.04789.X  0.823
2006 Lampert A, Hains BC, Waxman SG. Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury. Experimental Brain Research. 174: 660-6. PMID 16718433 DOI: 10.1007/s00221-006-0511-x  0.822
2006 Rush AM, Dib-Hajj SD, Liu S, Cummins TR, Black JA, Waxman SG. A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 8245-50. PMID 16702558 DOI: 10.1073/Pnas.0602813103  0.635
2006 Hains BC, Waxman SG. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4308-17. PMID 16624951 DOI: 10.1523/JNEUROSCI.0003-06.2006  0.776
2006 Choi JS, Hudmon A, Waxman SG, Dib-Hajj SD. Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. Journal of Neurophysiology. 96: 97-108. PMID 16598065 DOI: 10.1152/jn.00854.2005  0.418
2006 Black JA, Waxman SG, Smith KJ. Remyelination of dorsal column axons by endogenous Schwann cells restores the normal pattern of Nav1.6 and Kv1.2 at nodes of Ranvier. Brain : a Journal of Neurology. 129: 1319-29. PMID 16537565 DOI: 10.1093/Brain/Awl057  0.379
2006 Waxman SG, Hains BC. Fire and phantoms after spinal cord injury: Na+ channels and central pain. Trends in Neurosciences. 29: 207-15. PMID 16494954 DOI: 10.1016/j.tins.2006.02.003  0.776
2006 Hains BC, Saab CY, Waxman SG. Alterations in burst firing of thalamic VPL neurons and reversal by Na(v)1.3 antisense after spinal cord injury. Journal of Neurophysiology. 95: 3343-52. PMID 16481457 DOI: 10.1152/Jn.01009.2005  0.776
2006 Sasaki M, Black JA, Lankford KL, Tokuno HA, Waxman SG, Kocsis JD. Molecular reconstruction of nodes of Ranvier after remyelination by transplanted olfactory ensheathing cells in the demyelinated spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1803-12. PMID 16467529 DOI: 10.1523/JNEUROSCI.3611-05.2006  0.569
2006 Han C, Rush AM, Dib-Hajj SD, Li S, Xu Z, Wang Y, Tyrrell L, Wang X, Yang Y, Waxman SG. Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7. Annals of Neurology. 59: 553-8. PMID 16392115 DOI: 10.1002/ana.20776  0.356
2006 Sasaki M, Hains BC, Lankford KL, Waxman SG, Kocsis JD. Protection of corticospinal tract neurons after dorsal spinal cord transection and engraftment of olfactory ensheathing cells. Glia. 53: 352-9. PMID 16288464 DOI: 10.1002/glia.20285  0.8
2006 Wang S, Davis BM, Zwick M, Waxman SG, Albers KM. Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged mice. Neurobiology of Aging. 27: 895-903. PMID 15979214 DOI: 10.1016/J.Neurobiolaging.2005.04.009  0.367
2006 Dib-Hajj SD, Rush AM, Cummins TR, Waxman SG. Mutations in the sodium channel Nav1.7 underlie inherited erythromelalgia Drug Discovery Today: Disease Mechanisms. 3: 343-350. DOI: 10.1016/J.Ddmec.2006.09.005  0.544
2005 Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacological Reviews. 57: 397-409. PMID 16382098 DOI: 10.1124/pr.57.4.4  0.602
2005 Hains BC, Waxman SG. Neuroprotection by sodium channel blockade with phenytoin in an experimental model of glaucoma. Investigative Ophthalmology & Visual Science. 46: 4164-9. PMID 16249495 DOI: 10.1167/iovs.05-0618  0.776
2005 Hains BC, Saab CY, Waxman SG. Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury. Brain : a Journal of Neurology. 128: 2359-71. PMID 16109750 DOI: 10.1093/Brain/Awh623  0.776
2005 Wittmack EK, Rush AM, Hudmon A, Waxman SG, Dib-Hajj SD. Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6621-30. PMID 16014723 DOI: 10.1523/Jneurosci.0541-05.2005  0.818
2005 Leffler A, Herzog RI, Dib-Hajj SD, Waxman SG, Cummins TR. Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue. PflüGers Archiv : European Journal of Physiology. 451: 454-63. PMID 15981012 DOI: 10.1007/S00424-005-1463-X  0.544
2005 Dib-Hajj SD, Rush AM, Cummins TR, Hisama FM, Novella S, Tyrrell L, Marshall L, Waxman SG. Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons. Brain : a Journal of Neurology. 128: 1847-54. PMID 15958509 DOI: 10.1093/Brain/Awh514  0.639
2005 Cummins TR, Dib-Hajj SD, Herzog RI, Waxman SG. Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons. Febs Letters. 579: 2166-70. PMID 15811336 DOI: 10.1016/J.Febslet.2005.03.009  0.544
2005 Liu C, Cummins TR, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD. CAP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Na(v)1.8. Molecular and Cellular Neurosciences. 28: 636-49. PMID 15797711 DOI: 10.1016/J.Mcn.2004.11.007  0.604
2005 Craner MJ, Damarjian TG, Liu S, Hains BC, Lo AC, Black JA, Newcombe J, Cuzner ML, Waxman SG. Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia. 49: 220-9. PMID 15390090 DOI: 10.1002/glia.20112  0.811
2005 Cummins TR, Waxman SG. Neuronal Blocking Factors in Demyelinating Diseases Multiple Sclerosis as a Neuronal Disease. 317-326. DOI: 10.1016/B978-012738761-1/50023-7  0.526
2005 Stys PK, Waxman SG. Molecular Mechanisms of Calcium Influx in Axonal Degeneration Multiple Sclerosis as a Neuronal Disease. 275-292. DOI: 10.1016/B978-012738761-1/50020-1  0.506
2004 Waxman SG, Craner MJ, Black JA. Na+ channel expression along axons in multiple sclerosis and its models. Trends in Pharmacological Sciences. 25: 584-91. PMID 15491781 DOI: 10.1016/j.tips.2004.09.001  0.369
2004 Damarjian TG, Craner MJ, Black JA, Waxman SG. Upregulation and colocalization of p75 and Nav1.8 in Purkinje neurons in experimental autoimmune encephalomyelitis. Neuroscience Letters. 369: 186-90. PMID 15464262 DOI: 10.1016/j.neulet.2004.07.023  0.392
2004 Cummins TR, Dib-Hajj SD, Waxman SG. Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8232-6. PMID 15385606 DOI: 10.1523/Jneurosci.2695-04.2004  0.66
2004 Shah BS, Rush AM, Liu S, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7387-99. PMID 15317864 DOI: 10.1523/JNEUROSCI.0322-04.2004  0.412
2004 Choi JS, Tyrrell L, Waxman SG, Dib-Hajj SD. Functional role of the C-terminus of voltage-gated sodium channel Na(v)1.8. Febs Letters. 572: 256-60. PMID 15304358 DOI: 10.1016/j.febslet.2004.07.047  0.363
2004 Wittmack EK, Rush AM, Craner MJ, Goldfarb M, Waxman SG, Dib-Hajj SD. Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6765-75. PMID 15282281 DOI: 10.1523/Jneurosci.1628-04.2004  0.823
2004 Hains BC, Saab CY, Lo AC, Waxman SG. Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal conduction, and improves functional motor recovery after contusion SCI. Experimental Neurology. 188: 365-77. PMID 15246836 DOI: 10.1016/J.Expneurol.2004.04.001  0.776
2004 Hains BC, Saab CY, Klein JP, Craner MJ, Waxman SG. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4832-9. PMID 15152043 DOI: 10.1523/Jneurosci.0300-04.2004  0.834
2004 Craner MJ, Newcombe J, Black JA, Hartle C, Cuzner ML, Waxman SG. Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger. Proceedings of the National Academy of Sciences of the United States of America. 101: 8168-73. PMID 15148385 DOI: 10.1073/pnas.0402765101  0.387
2004 Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H. Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy. Brain Research. 1000: 102-9. PMID 15053958 DOI: 10.1016/j.brainres.2003.11.051  0.658
2004 Black JA, Liu S, Tanaka M, Cummins TR, Waxman SG. Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain. 108: 237-47. PMID 15030943 DOI: 10.1016/J.Pain.2003.12.035  0.65
2004 Klein JP, Hains BC, Craner MJ, Black JA, Waxman SG. Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus. Neurobiology of Disease. 15: 221-8. PMID 15006692 DOI: 10.1016/j.nbd.2003.10.009  0.788
2004 Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG. Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain : a Journal of Neurology. 127: 294-303. PMID 14662515 DOI: 10.1093/brain/awh032  0.812
2003 Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XXXIX. Compendium of voltage-gated ion channels: sodium channels. Pharmacological Reviews. 55: 575-8. PMID 14657413 DOI: 10.1124/Pr.55.4.7  0.594
2003 Craner MJ, Kataoka Y, Lo AC, Black JA, Baker D, Waxman SG. Temporal course of upregulation of Na(v)1.8 in Purkinje neurons parallels the progression of clinical deficit in experimental allergic encephalomyelitis. Journal of Neuropathology and Experimental Neurology. 62: 968-75. PMID 14533785 DOI: 10.1093/Jnen/62.9.968  0.396
2003 Hains BC, Klein JP, Saab CY, Craner MJ, Black JA, Waxman SG. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8881-92. PMID 14523090 DOI: 10.1523/Jneurosci.23-26-08881.2003  0.83
2003 Klein JP, Tendi EA, Dib-Hajj SD, Fields RD, Waxman SG. Patterned electrical activity modulates sodium channel expression in sensory neurons. Journal of Neuroscience Research. 74: 192-8. PMID 14515348 DOI: 10.1002/jnr.10768  0.59
2003 Herzog RI, Liu C, Waxman SG, Cummins TR. Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8261-70. PMID 12967988 DOI: 10.1523/Jneurosci.23-23-08261.2003  0.544
2003 Klein JP, Waxman SG. The brain in diabetes: molecular changes in neurons and their implications for end-organ damage. The Lancet. Neurology. 2: 548-54. PMID 12941577 DOI: 10.1016/S1474-4422(03)00503-9  0.49
2003 Lo AC, Saab CY, Black JA, Waxman SG. Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo. Journal of Neurophysiology. 90: 3566-71. PMID 12904334 DOI: 10.1152/Jn.00434.2003  0.382
2003 Saab CY, Cummins TR, Waxman SG. GTP gamma S increases Nav1.8 current in small-diameter dorsal root ganglia neurons. Experimental Brain Research. 152: 415-9. PMID 12898089 DOI: 10.1007/S00221-003-1565-7  0.606
2003 Tokuno HA, Kocsis JD, Waxman SG. Noninactivating, tetrodotoxin-sensitive Na+ conductance in peripheral axons. Muscle & Nerve. 28: 212-7. PMID 12872326 DOI: 10.1002/mus.10421  0.606
2003 Herzog RI, Cummins TR, Ghassemi F, Dib-Hajj SD, Waxman SG. Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons. The Journal of Physiology. 551: 741-50. PMID 12843211 DOI: 10.1111/J.1469-7793.2003.00741.X  0.544
2003 Craner MJ, Lo AC, Black JA, Waxman SG. Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination. Brain : a Journal of Neurology. 126: 1552-61. PMID 12805113 DOI: 10.1093/brain/awg153  0.388
2003 Weisman D, Hisama FM, Waxman SG, Blumenfeld H. Going deep to cut the link: cortical disconnection syndrome caused by a thalamic lesion. Neurology. 60: 1865-6. PMID 12796557 DOI: 10.1212/01.Wnl.0000066051.14414.Ff  0.486
2003 Hains BC, Black JA, Waxman SG. Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury. The Journal of Comparative Neurology. 462: 328-41. PMID 12794736 DOI: 10.1002/cne.10733  0.791
2003 Rugiero F, Mistry M, Sage D, Black JA, Waxman SG, Crest M, Clerc N, Delmas P, Gola M. Selective expression of a persistent tetrodotoxin-resistant Na+ current and NaV1.9 subunit in myenteric sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2715-25. PMID 12684457 DOI: 10.1523/Jneurosci.23-07-02715.2003  0.4
2003 Craner MJ, Lo AC, Black JA, Baker D, Newcombe J, Cuzner ML, Waxman SG. Annexin II/p11 is up-regulated in Purkinje cells in EAE and MS. Neuroreport. 14: 555-8. PMID 12657884 DOI: 10.1097/00001756-200303240-00005  0.324
2003 Baker MD, Chandra SY, Ding Y, Waxman SG, Wood JN. GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones. The Journal of Physiology. 548: 373-82. PMID 12651922 DOI: 10.1113/jphysiol.2003.039131  0.388
2003 Black JA, Cummins TR, Yoshimura N, de Groat WC, Waxman SG. Tetrodotoxin-resistant sodium channels Na(v)1.8/SNS and Na(v)1.9/NaN in afferent neurons innervating urinary bladder in control and spinal cord injured rats. Brain Research. 963: 132-8. PMID 12560118 DOI: 10.1016/S0006-8993(02)03957-4  0.636
2003 Cummins TR, Renganathan M, Stys PK, Herzog RI, Scarfo K, Horn R, Dib-Hajj SD, Waxman SG. The pentapeptide QYNAD does not block voltage-gated sodium channels. Neurology. 60: 224-9. PMID 12552035 DOI: 10.1212/01.Wnl.0000042423.36650.Bd  0.738
2003 Renganathan M, Gelderblom M, Black JA, Waxman SG. Expression of Nav1.8 sodium channels perturbs the firing patterns of cerebellar Purkinje cells. Brain Research. 959: 235-42. PMID 12493611 DOI: 10.1016/S0006-8993(02)03750-2  0.406
2003 Liu CJ, Dib-Hajj SD, Renganathan M, Cummins TR, Waxman SG. Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B. The Journal of Biological Chemistry. 278: 1029-36. PMID 12401812 DOI: 10.1074/Jbc.M207074200  0.544
2003 Rugiero F, Clerc N, Mistry M, Sage D, Black J, Waxman S, Crest M, Delmas P, Gola M. Selective expression of a persistent Ttx-resistant Na+ current and Navl.9 subunit in myenteric sensory neurons Gastroenterology. 124: A343. DOI: 10.1016/S0016-5085(03)81730-4  0.36
2003 Stys PK, Waxman SG. Ischemic White Matter Damage Myelin Biology and Disorders. 2: 985-1007. DOI: 10.1016/B978-012439510-7/50094-2  0.459
2002 Cummins TR, Dib-Hajj SD, Waxman SG, Donnelly DF. Characterization and developmental changes of Na+ currents of petrosal neurons with projections to the carotid body. Journal of Neurophysiology. 88: 2993-3002. PMID 12466424 DOI: 10.1152/Jn.00350.2002  0.64
2002 Craner MJ, Klein JP, Renganathan M, Black JA, Waxman SG. Changes of sodium channel expression in experimental painful diabetic neuropathy. Annals of Neurology. 52: 786-92. PMID 12447933 DOI: 10.1002/ana.10364  0.58
2002 Dib-Hajj SD, Tyrrell L, Waxman SG. Structure of the sodium channel gene SCN11A: evidence for intron-to-exon conversion model and implications for gene evolution. Molecular Neurobiology. 26: 235-50. PMID 12428758 DOI: 10.1385/MN:26:2-3:235  0.365
2002 Hains BC, Black JA, Waxman SG. Primary motor neurons fail to up-regulate voltage-gated sodium channel Na(v)1.3/brain type III following axotomy resulting from spinal cord injury. Journal of Neuroscience Research. 70: 546-52. PMID 12404508 DOI: 10.1002/jnr.10402  0.821
2002 Black JA, Renganathan M, Waxman SG. Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction. Brain Research. Molecular Brain Research. 105: 19-28. PMID 12399104 DOI: 10.1016/S0169-328X(02)00385-6  0.392
2002 Lo AC, Black JA, Waxman SG. Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis. Neuroreport. 13: 1909-12. PMID 12395089 DOI: 10.1097/00001756-200210280-00015  0.37
2002 Saab CY, Cummins TR, Dib-Hajj SD, Waxman SG. Molecular determinant of Na(v)1.8 sodium channel resistance to the venom from the scorpion Leiurus quinquestriatus hebraeus. Neuroscience Letters. 331: 79-82. PMID 12361845 DOI: 10.1016/S0304-3940(02)00860-1  0.544
2002 Craner MJ, Klein JP, Black JA, Waxman SG. Preferential expression of IGF-I in small DRG neurons and down-regulation following injury. Neuroreport. 13: 1649-52. PMID 12352620 DOI: 10.1097/00001756-200209160-00016  0.548
2002 Fang X, Djouhri L, Black JA, Dib-Hajj SD, Waxman SG, Lawson SN. The presence and role of the tetrodotoxin-resistant sodium channel Na(v)1.9 (NaN) in nociceptive primary afferent neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7425-33. PMID 12196564 DOI: 10.1523/Jneurosci.22-17-07425.2002  0.352
2002 Klein JP, Craner MJ, Cummins TR, Black JA, Waxman SG. Sodium channel expression in hypothalamic osmosensitive neurons in experimental diabetes. Neuroreport. 13: 1481-4. PMID 12167778 DOI: 10.1097/00001756-200208070-00027  0.678
2002 Leffler A, Cummins TR, Dib-Hajj SD, Hormuzdiar WN, Black JA, Waxman SG. GDNF and NGF reverse changes in repriming of TTX-sensitive Na(+) currents following axotomy of dorsal root ganglion neurons. Journal of Neurophysiology. 88: 650-8. PMID 12163518 DOI: 10.1152/Jn.2002.88.2.650  0.638
2002 Black JA, Waxman SG. Molecular identities of two tetrodotoxin-resistant sodium channels in corneal axons. Experimental Eye Research. 75: 193-9. PMID 12137764 DOI: 10.1006/exer.2002.2014  0.41
2002 Black JA, Dusart I, Sotelo C, Waxman SG. Axotomy does not up-regulate expression of sodium channel Na(v)1.8 in Purkinje cells. Brain Research. Molecular Brain Research. 101: 126-31. PMID 12007840 DOI: 10.1016/S0169-328X(02)00200-0  0.411
2002 Dib-Hajj S, Black JA, Cummins TR, Waxman SG. NaN/Nav1.9: a sodium channel with unique properties. Trends in Neurosciences. 25: 253-9. PMID 11972962 DOI: 10.1016/S0166-2236(02)02150-1  0.659
2002 White BH, Cummins TR, Wolf DH, Waxman SG, Russell DS, Kaczmarek LK. HSV-1 helper virus 5dl1.2 suppresses sodium currents in amplicon-transduced neurons. Journal of Neurophysiology. 87: 2149-57. PMID 11929932 DOI: 10.1152/Jn.00498.2001  0.577
2002 Liu CN, Devor M, Waxman SG, Kocsis JD. Subthreshold oscillations induced by spinal nerve injury in dissociated muscle and cutaneous afferents of mouse DRG. Journal of Neurophysiology. 87: 2009-17. PMID 11929919 DOI: 10.1152/jn.00705.2001  0.682
2002 Renganathan M, Cummins TR, Waxman SG. Nitric oxide blocks fast, slow, and persistent Na+ channels in C-type DRG neurons by S-nitrosylation. Journal of Neurophysiology. 87: 761-75. PMID 11826045 DOI: 10.1152/Jn.00369.2001  0.621
2002 Waxman SG, Cummins TR, Black JA, Dib-Hajj S. Diverse functions and dynamic expression of neuronal sodium channels. Novartis Foundation Symposium. 241: 34-51; discussion 51. PMID 11771649 DOI: 10.1002/0470846682.Ch4  0.647
2001 Tyrrell L, Renganathan M, Dib-Hajj SD, Waxman SG. Glycosylation alters steady-state inactivation of sodium channel Nav1.9/NaN in dorsal root ganglion neurons and is developmentally regulated. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9629-37. PMID 11739573 DOI: 10.1523/Jneurosci.21-24-09629.2001  0.403
2001 Liu CJ, Dib-Hajj SD, Black JA, Greenwood J, Lian Z, Waxman SG. Direct interaction with contactin targets voltage-gated sodium channel Na(v)1.9/NaN to the cell membrane. The Journal of Biological Chemistry. 276: 46553-61. PMID 11581273 DOI: 10.1074/jbc.M108699200  0.427
2001 Everill B, Cummins TR, Waxman SG, Kocsis JD. Sodium currents of large (Abeta-type) adult cutaneous afferent dorsal root ganglion neurons display rapid recovery from inactivation before and after axotomy. Neuroscience. 106: 161-9. PMID 11564426 DOI: 10.1016/S0306-4522(01)00258-5  0.71
2001 Herzog RI, Cummins TR, Waxman SG. Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. Journal of Neurophysiology. 86: 1351-64. PMID 11535682 DOI: 10.1152/Jn.2001.86.3.1351  0.598
2001 Renganathan M, Cummins TR, Waxman SG. Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. Journal of Neurophysiology. 86: 629-40. PMID 11495938 DOI: 10.1152/Jn.2001.86.2.629  0.628
2001 Cummins TR, Aglieco F, Renganathan M, Herzog RI, Dib-Hajj SD, Waxman SG. Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5952-61. PMID 11487618 DOI: 10.1523/Jneurosci.21-16-05952.2001  0.544
2001 Kearney JA, Plummer NW, Smith MR, Kapur J, Cummins TR, Waxman SG, Goldin AL, Meisler MH. A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience. 102: 307-17. PMID 11166117 DOI: 10.1016/S0306-4522(00)00479-6  0.718
2000 Waxman SG, Cummins TR, Dib-Hajj SD, Black JA. Voltage-gated sodium channels and the molecular pathogenesis of pain: a review. Journal of Rehabilitation Research and Development. 37: 517-28. PMID 11322150  0.492
2000 Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA. Nomenclature of voltage-gated sodium channels. Neuron. 28: 365-8. PMID 11144347 DOI: 10.1016/S0896-6273(00)00116-1  0.591
2000 Waxman SG, Dib-Hajj S, Cummins TR, Black JA. Sodium channels and their genes: dynamic expression in the normal nervous system, dysregulation in disease states(1). Brain Research. 886: 5-14. PMID 11119683 DOI: 10.1016/S0006-8993(00)02774-8  0.635
2000 Cummins TR, Black JA, Dib-Hajj SD, Waxman SG. Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8754-61. PMID 11102483 DOI: 10.1523/Jneurosci.20-23-08754.2000  0.634
2000 Cummins TR, Dib-Hajj SD, Black JA, Waxman SG. Sodium channels and the molecular pathophysiology of pain. Progress in Brain Research. 129: 3-19. PMID 11098678 DOI: 10.1016/S0079-6123(00)29002-X  0.662
2000 Sleeper AA, Cummins TR, Dib-Hajj SD, Hormuzdiar W, Tyrrell L, Waxman SG, Black JA. Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7279-89. PMID 11007885 DOI: 10.1523/Jneurosci.20-19-07279.2000  0.643
2000 Renganathan M, Cummins TR, Hormuzdiar WN, Waxman SG. alpha-SNS produces the slow TTX-resistant sodium current in large cutaneous afferent DRG neurons. Journal of Neurophysiology. 84: 710-8. PMID 10938298 DOI: 10.1152/Jn.2000.84.2.710  0.624
2000 Bendahhou S, Cummins TR, Hahn AF, Langlois S, Waxman SG, Ptácek LJ. A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation. The Journal of Clinical Investigation. 106: 431-8. PMID 10930446 DOI: 10.1172/Jci9654  0.591
2000 Renganathan M, Cummins TR, Hormuzdiar WN, Black JA, Waxman SG. Nitric oxide is an autocrine regulator of Na(+) currents in axotomized C-type DRG neurons. Journal of Neurophysiology. 83: 2431-42. PMID 10758144 DOI: 10.1152/Jn.2000.83.4.2431  0.616
2000 Fjell J, Hjelmström P, Hormuzdiar W, Milenkovic M, Aglieco F, Tyrrell L, Dib-Hajj S, Waxman SG, Black JA. Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors. Neuroreport. 11: 199-202. PMID 10683857 DOI: 10.1097/00001756-200001170-00039  0.428
1999 Waxman SG, Wood JN. Sodium channels: from mechanisms to medicines? Brain Research Bulletin. 50: 309-10. PMID 10643411 DOI: 10.1016/S0361-9230(99)00158-6  0.343
1999 Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN, Waxman SG. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC43. PMID 10594087 DOI: 10.1523/Jneurosci.19-24-J0001.1999  0.609
1999 Dib-Hajj SD, Tyrrell L, Cummins TR, Black JA, Wood PM, Waxman SG. Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons. Febs Letters. 462: 117-20. PMID 10580103 DOI: 10.1016/S0014-5793(99)01519-7  0.628
1999 Dib-Hajj SD, Fjell J, Cummins TR, Zheng Z, Fried K, LaMotte R, Black JA, Waxman SG. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain. 83: 591-600. PMID 10568868 DOI: 10.1016/S0304-3959(99)00169-4  0.65
1999 Black JA, Cummins TR, Plumpton C, Chen YH, Hormuzdiar W, Clare JJ, Waxman SG. Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. Journal of Neurophysiology. 82: 2776-85. PMID 10561444 DOI: 10.1152/Jn.1999.82.5.2776  0.654
1999 Waxman SG, Cummins TR, Dib-Hajj S, Fjell J, Black JA. Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain. Muscle & Nerve. 22: 1177-87. PMID 10454712 DOI: 10.1002/(Sici)1097-4598(199909)22:9<1177::Aid-Mus3>3.0.Co;2-P  0.659
1999 Dib-Hajj SD, Tyrrell L, Escayg A, Wood PM, Meisler MH, Waxman SG. Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN Genomics. 59: 309-318. PMID 10444332 DOI: 10.1006/Geno.1999.5890  0.371
1999 Longuemare MC, Rose CR, Farrell K, Ransom BR, Waxman SG, Swanson RA. K(+)-induced reversal of astrocyte glutamate uptake is limited by compensatory changes in intracellular Na+. Neuroscience. 93: 285-92. PMID 10430492 DOI: 10.1016/S0306-4522(99)00152-9  0.672
1999 Fjell J, Cummins TR, Davis BM, Albers KM, Fried K, Waxman SG, Black JA. Sodium channel expression in NGF-overexpressing transgenic mice. Journal of Neuroscience Research. 57: 39-47. PMID 10397634 DOI: 10.1002/(Sici)1097-4547(19990701)57:1<39::Aid-Jnr5>3.0.Co;2-M  0.608
1999 Waxman SG, Dib-Hajj S, Cummins TR, Black JA. Sodium channels and pain. Proceedings of the National Academy of Sciences of the United States of America. 96: 7635-9. PMID 10393872 DOI: 10.1073/Pnas.96.14.7635  0.665
1999 Bendahhou S, Cummins TR, Kwiecinski H, Waxman SG, Ptácek LJ. Characterization of a new sodium channel mutation at arginine 1448 associated with moderate Paramyotonia congenita in humans. The Journal of Physiology. 518: 337-44. PMID 10381583 DOI: 10.1111/J.1469-7793.1999.0337P.X  0.596
1999 Fjell J, Cummins TR, Dib-Hajj SD, Fried K, Black JA, Waxman SG. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. Brain Research. Molecular Brain Research. 67: 267-82. PMID 10216225 DOI: 10.1016/S0169-328X(99)00070-4  0.62
1999 Ishikawa K, Tanaka M, Black JA, Waxman SG. Changes in expression of voltage-gated potassium channels in dorsal root ganglion neurons following axotomy. Muscle & Nerve. 22: 502-7. PMID 10204786 DOI: 10.1002/(SICI)1097-4598(199904)22:4<502::AID-MUS12>3.0.CO;2-K  0.459
1999 Fjell J, Cummins TR, Fried K, Black JA, Waxman SG. In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons. Journal of Neurophysiology. 81: 803-10. PMID 10036280 DOI: 10.1152/Jn.1999.81.2.803  0.614
1999 Tanaka M, Cummins TR, Ishikawa K, Black JA, Ibata Y, Waxman SG. Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input. Proceedings of the National Academy of Sciences of the United States of America. 96: 1088-93. PMID 9927698 DOI: 10.1073/Pnas.96.3.1088  0.632
1999 Imaizumi T, Kocsis JD, Waxman SG. The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter. Brain Research. 817: 84-92. PMID 9889329 DOI: 10.1016/S0006-8993(98)01214-1  0.596
1999 Bendahhou S, Cummins TR, Tawil R, Waxman SG, Ptácek LJ. Activation and Inactivation of the Voltage-Gated Sodium Channel: Role of Segment S5 Revealed by a Novel Hyperkalaemic Periodic Paralysis Mutation The Journal of Neuroscience. 19: 4762-4771. DOI: 10.1523/Jneurosci.19-12-04762.1999  0.544
1998 Imaizumi T, Lankford KL, Waxman SG, Greer CA, Kocsis JD. Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyelinated dorsal columns of the rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6176-85. PMID 9698311 DOI: 10.1523/Jneurosci.18-16-06176.1998  0.553
1998 Dib-Hajj SD, Tyrrell L, Black JA, Waxman SG. NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy Proceedings of the National Academy of Sciences of the United States of America. 95: 8963-8968. PMID 9671787 DOI: 10.1073/pnas.95.15.8963  0.437
1998 Black JA, Dib-Hajj S, Cohen S, Hinson AW, Waxman SG. Glial cells have heart: rH1 Na+ channel mRNA and protein in spinal cord astrocytes. Glia. 23: 200-8. PMID 9633805 DOI: 10.1002/(SICI)1098-1136(199807)23:3<200::AID-GLIA3>3.0.CO;2-8  0.379
1998 Diss JK, Stewart D, Fraser SP, Black JA, Dib-Hajj S, Waxman SG, Archer SN, Djamgoz MB. Expression of skeletal muscle-type voltage-gated Na+ channel in rat and human prostate cancer cell lines. Febs Letters. 427: 5-10. PMID 9613589 DOI: 10.1016/S0014-5793(98)00378-0  0.325
1998 Tanaka M, Cummins TR, Ishikawa K, Dib-Hajj SD, Black JA, Waxman SG. SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport. 9: 967-72. PMID 9601651 DOI: 10.1097/00001756-199804200-00003  0.64
1998 Dib-Hajj SD, Black JA, Cummins TR, Kenney AM, Kocsis JD, Waxman SG. Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. Journal of Neurophysiology. 79: 2668-76. PMID 9582237 DOI: 10.1152/Jn.1998.79.5.2668  0.7
1998 Rose CR, Waxman SG, Ransom BR. Effects of glucose deprivation, chemical hypoxia, and simulated ischemia on Na+ homeostasis in rat spinal cord astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3554-62. PMID 9570787 DOI: 10.1523/Jneurosci.18-10-03554.1998  0.663
1998 Lankford KL, Waxman SG, Kocsis JD. Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion. The Journal of Comparative Neurology. 391: 11-29. PMID 9527536 DOI: 10.1002/(SICI)1096-9861(19980202)391:1<11::AID-CNE2>3.0.CO;2-U  0.57
1998 Buschmann T, Martin-Villalba A, Kocsis JD, Waxman SG, Zimmermann M, Herdegen T. Expression of Jun, Fos, and ATF-2 proteins in axotomized explanted and cultured adult rat dorsal root ganglia. Neuroscience. 84: 163-76. PMID 9522371 DOI: 10.1016/S0306-4522(97)00487-9  0.556
1998 Imaizumi T, Kocsis JD, Waxman SG. Resistance to anoxic injury in the dorsal columns of adult rat spinal cord following demyelination. Brain Research. 779: 292-6. PMID 9473700 DOI: 10.1016/S0006-8993(97)01171-2  0.542
1998 Fern R, Davis P, Waxman SG, Ransom BR. Axon conduction and survival in CNS white matter during energy deprivation: a developmental study. Journal of Neurophysiology. 79: 95-105. PMID 9425180 DOI: 10.1152/Jn.1998.79.1.95  0.675
1998 Fjell J, Dib-Hajj S, Fried K, Black JA, Waxman SG. Differential expression of sodium channel genes in retinal ganglion cells. Brain Research. Molecular Brain Research. 50: 197-204. PMID 9406935 DOI: 10.1016/S0169-328X(97)00187-3  0.376
1998 Cummins TR, Howe JR, Waxman SG. Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel The Journal of Neuroscience. 18: 9607-9619. DOI: 10.1523/Jneurosci.18-23-09607.1998  0.544
1997 Steffensen I, Waxman SG, Mills L, Stys PK. Immunolocalization of the Na(+)-Ca2+ exchanger in mammalian myelinated axons. Brain Research. 776: 1-9. PMID 9439790 DOI: 10.1016/S0006-8993(97)00868-8  0.604
1997 Hinson AW, Gu XQ, Dib-Hajj S, Black JA, Waxman SG. Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro. Glia. 21: 339-49. PMID 9419009 DOI: 10.1002/(SICI)1098-1136(199712)21:4<339::AID-GLIA1>3.0.CO;2-Z  0.396
1997 Rose CR, Ransom BR, Waxman SG. Pharmacological characterization of Na+ influx via voltage-gated Na+ channels in spinal cord astrocytes. Journal of Neurophysiology. 78: 3249-58. PMID 9405543 DOI: 10.1152/Jn.1997.78.6.3249  0.663
1997 Felts PA, Black JA, Dib-Hajj SD, Waxman SG. NaG: a sodium channel-like mRNA shared by Schwann cells and other neural crest derivatives. Glia. 21: 269-76. PMID 9383036 DOI: 10.1002/(SICI)1098-1136(199711)21:3<269::AID-GLIA2>3.0.CO;2-0  0.391
1997 Dib-Hajj SD, Ishikawa K, Cummins TR, Waxman SG. Insertion of a SNS-specific tetrapeptide in S3-S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage-gated Na channel mu1 in HEK293 cells. Febs Letters. 416: 11-4. PMID 9369222 DOI: 10.1016/S0014-5793(97)01154-X  0.544
1997 Black JA, Felts P, Smith KJ, Kocsis JD, Waxman SG. Distribution of sodium channels in chronically demyelinated spinal cord axons: immunoultrastructural localization and electrophysiological observations. Brain Research 544 (1991) 59-70. Brain Research. 761: 1. PMID 9247057 DOI: 10.1016/S0006-8993(97)00544-1  0.518
1997 Black JA, Langworthy K, Hinson AW, Dib-Hajj SD, Waxman SG. NGF has opposing effects on Na+ channel III and SNS gene expression in spinal sensory neurons. Neuroreport. 8: 2331-5. PMID 9243635 DOI: 10.1097/00001756-199707070-00046  0.354
1997 Oyelese AA, Rizzo MA, Waxman SG, Kocsis JD. Differential effects of NGF and BDNF on axotomy-induced changes in GABA(A)-receptor-mediated conductance and sodium currents in cutaneous afferent neurons. Journal of Neurophysiology. 78: 31-42. PMID 9242258 DOI: 10.1152/Jn.1997.78.1.31  0.587
1997 Imaizumi T, Kocsis JD, Waxman SG. Anoxic injury in the rat spinal cord: pharmacological evidence for multiple steps in Ca(2+)-dependent injury of the dorsal columns. Journal of Neurotrauma. 14: 299-311. PMID 9199396 DOI: 10.1089/Neu.1997.14.299  0.569
1997 Sashihara S, Waxman SG, Greer CA. Downregulation of Na+ channel mRNA in olfactory bulb tufted cells following deafferentation. Neuroreport. 8: 1289-93. PMID 9175131 DOI: 10.1097/00001756-199703240-00046  0.364
1997 Gu XQ, Dib-Hajj S, Rizzo MA, Waxman SG. TTX-sensitive and -resistant Na+ currents, and mRNA for the TTX-resistant rH1 channel, are expressed in B104 neuroblastoma cells. Journal of Neurophysiology. 77: 236-46. PMID 9120565 DOI: 10.1152/JN.1997.77.1.236  0.359
1997 Felts PA, Yokoyama S, Dib-Hajj S, Black JA, Waxman SG. Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. Brain Research. Molecular Brain Research. 45: 71-82. PMID 9105672 DOI: 10.1016/S0169-328X(96)00241-0  0.342
1997 Dib-Hajj S, Black JA, Felts P, Waxman SG. Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomy. Proceedings of the National Academy of Sciences of the United States of America. 93: 14950-4. PMID 8962162 DOI: 10.1073/PNAS.93.25.14950  0.385
1997 Cummins TR, Waxman SG. Downregulation of Tetrodotoxin-Resistant Sodium Currents and Upregulation of a Rapidly Repriming Tetrodotoxin-Sensitive Sodium Current in Small Spinal Sensory Neurons after Nerve Injury The Journal of Neuroscience. 17: 3503-3514. DOI: 10.1523/Jneurosci.17-10-03503.1997  0.544
1997 Waxman SG, Kocsis JD. Spinal cord repair: Progress towards a daunting goal Neuroscientist. 3: 263-269. DOI: 10.1177/107385849700300414  0.536
1997 Hommou O, Hashi K, Felts PA, Waxman SG, Kocsis JD. Functional repair of demyelinated spinal cordaxons in the adult rat by transplantation of genetically-engineering Schwann cells Clinical Neurology and Neurosurgery. 99: S143. DOI: 10.1016/S0303-8467(97)81922-1  0.505
1996 Black JA, Dib-Hajj S, McNabola K, Jeste S, Rizzo MA, Kocsis JD, Waxman SG. Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs. Brain Research. Molecular Brain Research. 43: 117-31. PMID 9037525 DOI: 10.1016/S0169-328X(96)00163-5  0.588
1996 Waxman SG, Rizzo MA. The whiplash (hyperextension-flexion) syndrome: A disorder of dorsal root ganglion neurons? Journal of Neurotrauma. 13: 735-739. PMID 9002059 DOI: 10.1089/NEU.1996.13.735  0.313
1996 Fern R, Ransom BR, Waxman SG. Autoprotective mechanisms in the CNS: some new lessons from white matter. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 27: 107-29. PMID 8962597 DOI: 10.1007/BF02815088  0.665
1996 Fern R, Black JA, Ransom BR, Waxman SG. Cd(2+)-induced injury in CNS white matter. Journal of Neurophysiology. 76: 3264-73. PMID 8930271 DOI: 10.1152/Jn.1996.76.5.3264  0.675
1996 Roy ML, Saal D, Perney T, Sontheimer H, Waxman SG, Kaczmarek LK. Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides. Glia. 18: 177-84. PMID 8915650 DOI: 10.1002/(SICI)1098-1136(199611)18:3<177::AID-GLIA2>3.0.CO;2-X  0.39
1996 Black JA, Waxman SG. Sodium channel expression: A dynamic process in neurons and non-neuronal cells Developmental Neuroscience. 18: 139-152. PMID 8894443 DOI: 10.1159/000111403  0.408
1996 Sontheimer H, Black JA, Waxman SG. Voltage-gated Na+ channels in gila: Properties and possible functions Trends in Neurosciences. 19: 325-331. PMID 8843601 DOI: 10.1016/0166-2236(96)10039-4  0.409
1996 Sashihara S, Oh Y, Black JA, Waxman SG. Na+ channel beta 1 subunit mRNA expression in developing rat central nervous system. Brain Research. Molecular Brain Research. 34: 239-50. PMID 8750827 DOI: 10.1016/0169-328X(95)00168-R  0.349
1996 Waxman SG, Black JA. Expression of mRNA for a sodium channel in subfamily 2 in spinal sensory neurons Neurochemical Research. 21: 395-401. PMID 8734431 DOI: 10.1007/BF02527702  0.39
1996 Rizzo MA, Kocsis JD, Waxman SG. Mechanisms of paresthesiae, dysesthesiae, and hyperesthesiae: role of Na+ channel heterogeneity. European Neurology. 36: 3-12. PMID 8719643 DOI: 10.1159/000117192  0.623
1996 Honmou O, Felts PA, Waxman SG, Kocsis JD. Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3199-208. PMID 8627358 DOI: 10.1523/Jneurosci.16-10-03199.1996  0.553
1996 Sashihara S, Greer CA, Oh Y, Waxman SG. Cell-specific differential expression of Na(+)-channel beta 1-subunit mRNA in the olfactory system during postnatal development and after denervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 702-13. PMID 8551353 DOI: 10.1523/Jneurosci.16-02-00702.1996  0.302
1996 Fern R, Ransom BR, Waxman SG, Barinagarrementeria F, Figueroa T, Huebe J, Cantú C, Stegmayr B, Harmsen P, Rajakangas A, Rastenyté D, Sarti C, Thorvaldsen P, Tuomilehto J, Juby LC, et al. Minutes of the General Assembly of the European Stroke Council Cerebrovascular Diseases. 6: 117-117. DOI: 10.1159/000108008  0.663
1996 Fern R, Ransom BR, Waxman SG. White Matter Stroke: Autoprotective Mechanisms with Therapeutic Implications Cerebrovascular Diseases. 6: 59-65. DOI: 10.1159/000107999  0.663
1995 Rizzo MA, Kocsis JD, Waxman SG. Selective loss of slow and enhancement of fast Na+ currents in cutaneous afferent dorsal root ganglion neurones following axotomy. Neurobiology of Disease. 2: 87-96. PMID 8980012 DOI: 10.1006/Nbdi.1995.0009  0.622
1995 Black JA, Westenbroek RE, Catterall WA, Waxman SG. Type II brain sodium channel expression in non-neuronal cells: embryonic rat osteoblasts. Brain Research. Molecular Brain Research. 34: 89-98. PMID 8750864 DOI: 10.1016/0169-328X(95)00141-E  0.376
1995 Fern R, Waxman SG, Ransom BR. Endogenous GABA attenuates CNS white matter dysfunction following anoxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 699-708. PMID 7823173 DOI: 10.1523/Jneurosci.15-01-00699.1995  0.648
1995 Lankford KL, Rand MN, Waxman SG, Kocsis JD. Blocking Ca2+ mobilization with thapsigargin reduces neurite initiation in cultured adult rat DRG neurons. Brain Research. Developmental Brain Research. 84: 151-63. PMID 7743635 DOI: 10.1016/0165-3806(94)00159-W  0.538
1995 Oh Y, Sashihara S, Black JA, Waxman SG. Na+ channel beta 1 subunit mRNA: differential expression in rat spinal sensory neurons. Brain Research. Molecular Brain Research. 30: 357-61. PMID 7637585 DOI: 10.1016/0169-328X(95)00052-T  0.356
1995 Zur KB, Oh Y, Waxman SG, Black JA. Differential up-regulation of sodium channel alpha- and beta 1-subunit mRNAs in cultured embryonic DRG neurons following exposure to NGF. Brain Research. Molecular Brain Research. 30: 97-105. PMID 7609649 DOI: 10.1016/0169-328X(94)00283-K  0.346
1995 Ausim Azizi S, Fayad PB, Fulbright R, Giroux ML, Waxman SG. Clivus and cervical spinal osteomyelitis with epidural abscess presenting with multiple cranial neuropathies Clinical Neurology and Neurosurgery. 97: 239-244. PMID 7586856 DOI: 10.1016/0303-8467(95)00036-J  0.302
1995 Black JA, Westenbroek R, Minturn JE, Ransom BR, Catterall WA, Waxman SG. Isoform-specific expression of sodium channels in astrocytes in vitro: immunocytochemical observations. Glia. 14: 133-44. PMID 7558240 DOI: 10.1002/glia.440140208  0.698
1995 Felts PA, Black JA, Waxman SG. Expression of sodium channel α- and β-subunits in the nervous system of the myelin-deficient rat Journal of Neurocytology. 24: 654-666. PMID 7500121 DOI: 10.1007/BF01179816  0.347
1995 Fern R, Ransom BR, Waxman SG. Voltage-gated calcium channels in CNS white matter: role in anoxic injury. Journal of Neurophysiology. 74: 369-77. PMID 7472338 DOI: 10.1152/Jn.1995.74.1.369  0.702
1994 Utzschneider DA, Archer DR, Kocsis JD, Waxman SG, Duncan ID. Transplantation of glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin-deficient rat. Proceedings of the National Academy of Sciences of the United States of America. 91: 53-7. PMID 8278406 DOI: 10.1073/pnas.91.1.53  0.547
1994 Kocsis JD, Rand MN, Lankford KL, Waxman SG. Intracellular calcium mobilization and neurite outgrowth in mammalian neurons. Journal of Neurobiology. 25: 252-64. PMID 8195789 DOI: 10.1002/neu.480250306  0.525
1994 Utzschneider DA, Rand MN, Waxman SG, Kocsis JD. Nuclear and cytoplasmic Ca2+ signals in developing rat dorsal root ganglion neurons studied in excised tissue. Brain Research. 635: 231-7. PMID 8173960 DOI: 10.1016/0006-8993(94)91444-3  0.539
1994 Oh Y, Black JA, Waxman SG. Rat brain Na+ channel mRNAs in non-excitable Schwann cells Febs Letters. 350: 342-346. PMID 8070590 DOI: 10.1016/0014-5793(94)00807-8  0.389
1994 Honmou O, Utzschneider DA, Rizzo MA, Bowe CM, Waxman SG, Kocsis JD. Delayed depolarization and slow sodium currents in cutaneous afferents. Journal of Neurophysiology. 71: 1627-37. PMID 8064338 DOI: 10.1152/Jn.1994.71.5.1627  0.588
1994 Black JA, Yokoyama S, Waxman SG, Oh Y, Zur KB, Sontheimer H, Higashida H, Ransom BR. Sodium channel mRNAs in cultured spinal cord astrocytes: in situ hybridization in identified cell types. Brain Research. Molecular Brain Research. 23: 235-45. PMID 8057780 DOI: 10.1016/0169-328X(94)90230-5  0.688
1994 Waxman SG, Black JA, Ransom BR, Stys PK. Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca(2+)-mediated injury in myelinated CNS axons. Brain Research. 644: 197-204. PMID 8050031 DOI: 10.1016/0006-8993(94)91680-2  0.77
1994 Oh Y, Black JA, Waxman SG. The expression of rat brain voltage-sensitive Na+ channel mRNAs in astrocytes Molecular Brain Research. 23: 57-65. PMID 8028484 DOI: 10.1016/0169-328X(94)90211-9  0.382
1994 Black JA, Yokoyama S, Higashida H, Ransom BR, Waxman SG. Sodium channel mRNAs I, II and III in the CNS: cell-specific expression. Brain Research. Molecular Brain Research. 22: 275-89. PMID 8015385 DOI: 10.1016/0169-328X(94)90056-6  0.708
1994 Waxman SG, Kocsis JD, Black JA. Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy. Journal of Neurophysiology. 72: 466-70. PMID 7965028 DOI: 10.1152/Jn.1994.72.1.466  0.591
1994 Waxman SG, Utzschneider DA, Kocsis JD. Enhancement of action potential conduction following demyelination: experimental approaches to restoration of function in multiple sclerosis and spinal cord injury. Progress in Brain Research. 100: 233-43. PMID 7938524 DOI: 10.1016/S0079-6123(08)60790-6  0.595
1994 Rizzo MA, Kocsis JD, Waxman SG. Slow sodium conductances of dorsal root ganglion neurons: intraneuronal homogeneity and interneuronal heterogeneity. Journal of Neurophysiology. 72: 2796-815. PMID 7897490 DOI: 10.1152/Jn.1994.72.6.2796  0.593
1994 Fern R, Waxman SG, Ransom BR. Modulation of anoxic injury in CNS white matter by adenosine and interaction between adenosine and GABA. Journal of Neurophysiology. 72: 2609-16. PMID 7897478 DOI: 10.1152/Jn.1994.72.6.2609  0.676
1994 Kocsis JD, Rand MN, Lankford K, Waxman SG. Nuclear calcium elevation may initiate neurite outgrowth in mammalian neurons. Progress in Brain Research. 103: 137-51. PMID 7886202 DOI: 10.1016/S0079-6123(08)61134-6  0.542
1994 Leinders-Zufall T, Rand MN, Waxman SG, Kocsis JD. Differential role of two Ca(2+)-permeable non-NMDA glutamate channels in rat retinal ganglion cells: kainate-induced cytoplasmic and nuclear Ca2+ signals. Journal of Neurophysiology. 72: 2503-16. PMID 7884475 DOI: 10.1152/Jn.1994.72.5.2503  0.725
1994 Black JA, Westenbroek R, Ransom BR, Catterall WA, Waxman SG. Type II sodium channels in spinal cord astrocytes in situ: immunocytochemical observations. Glia. 12: 219-27. PMID 7851989 DOI: 10.1002/glia.440120307  0.704
1994 Stys PK, Waxman SG. Activity-dependent modulation of excitability: implications for axonal physiology and pathophysiology. Muscle & Nerve. 17: 969-74. PMID 7520532 DOI: 10.1002/Mus.880170902  0.57
1993 Ransom BR, Waxman SG, Stys PK. Anoxic injury of central myelinated axons: ionic mechanisms and pharmacology. Research Publications - Association For Research in Nervous and Mental Disease. 71: 121-51. PMID 8417464  0.743
1993 Stys PK, Sontheimer H, Ransom BR, Waxman SG. Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons. Proceedings of the National Academy of Sciences of the United States of America. 90: 6976-80. PMID 8394004 DOI: 10.1073/Pnas.90.15.6976  0.783
1993 Waxman SG, Sontheimer H, Black JA, Minturn JE, Ransom BR. Dynamic aspects of sodium channel expression in astrocytes. Advances in Neurology. 59: 135-55. PMID 8380514  0.636
1993 Fern R, Ransom BR, Stys PK, Waxman SG. Pharmacological protection of CNS white matter during anoxia: actions of phenytoin, carbamazepine and diazepam. The Journal of Pharmacology and Experimental Therapeutics. 266: 1549-55. PMID 8371157  0.738
1993 Waxman SG, Black JA, Ransom BR, Stys PK. Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium. Brain Research. 614: 137-45. PMID 8348309 DOI: 10.1016/0006-8993(93)91027-P  0.762
1993 Utzschneider DA, Thio C, Sontheimer H, Ritchie JM, Waxman SG, Kocsis JD. Action potential conduction and sodium channel content in the optic nerve of the myelin-deficient rat. Proceedings. Biological Sciences / the Royal Society. 254: 245-50. PMID 8108457 DOI: 10.1098/rspb.1993.0153  0.594
1993 Kocsis JD, Rand MN, Chen B, Waxman SG, Pourcho R. Kainate elicits elevated nuclear calcium signals in retinal neurons via calcium-induced calcium release. Brain Research. 616: 273-82. PMID 8102939 DOI: 10.1016/0006-8993(93)90218-C  0.511
1993 Waxman SG, Ritchie JM. Molecular dissection of the myelinated axon. Annals of Neurology. 33: 121-36. PMID 7679565 DOI: 10.1002/ana.410330202  0.396
1993 Duncan ID, Utzschneider DA, Archer PR, Kocsis JD, Waxman SG. MYELINATION OF MYELIN DEFICIENT RAT AXONS BY TRANSPLANTED GUA RESTORES CONDUCTION Journal of Neuropathology and Experimental Neurology. 52: 287. DOI: 10.1097/00005072-199305000-00108  0.53
1992 Waxman SG, Black JA, Stys PK, Ransom BR. Ultrastructural concomitants of anoxic injury and early post-anoxic recovery in rat optic nerve. Brain Research. 574: 105-19. PMID 1638387 DOI: 10.1016/0006-8993(92)90806-K  0.766
1992 Stys PK, Waxman SG, Ransom BR. Effects of temperature on evoked electrical activity and anoxic injury in CNS white matter. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 977-86. PMID 1400652 DOI: 10.1038/Jcbfm.1992.135  0.742
1992 Black JA, Sontheimer H, Minturn JE, Ransom BR, Waxman SG. The expression of sodium channels in astrocytes in situ and in vitro. Progress in Brain Research. 94: 89-107. PMID 1337617 DOI: 10.1016/S0079-6123(08)61742-2  0.717
1992 Sontheimer H, Ransom BR, Waxman SG. Different Na+ currents in P0- and P7-derived hippocampal astrocytes in vitro: evidence for a switch in Na+ channel expression in vivo. Brain Research. 597: 24-9. PMID 1335819 DOI: 10.1016/0006-8993(92)91501-5  0.663
1992 Sontheimer H, Black JA, Ransom BR, Waxman SG. Ion channels in spinal cord astrocytes in vitro. I. Transient expression of high levels of Na+ and K+ channels. Journal of Neurophysiology. 68: 985-1000. PMID 1331358 DOI: 10.1152/Jn.1992.68.4.985  0.724
1992 Minturn JE, Sontheimer H, Black JA, Ransom BR, Waxman SG. Sodium channel expression in optic nerve astrocytes chronically deprived of axonal contact. Glia. 6: 19-29. PMID 1324888 DOI: 10.1002/glia.440060104  0.68
1992 Stys PK, Ransom BR, Waxman SG. Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability. Journal of Neurophysiology. 67: 236-40. PMID 1313081 DOI: 10.1152/Jn.1992.67.1.236  0.768
1992 Stys PK, Waxman SG, Ransom BR. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 430-9. PMID 1311030 DOI: 10.1523/Jneurosci.12-02-00430.1992  0.776
1992 Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD. Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Research. 592: 283-97. PMID 1280518 DOI: 10.1016/0006-8993(92)91687-A  0.599
1991 Sontheimer H, Waxman SG, Ransom BR. Relationship between Na+ current expression and cell-cell coupling in astrocytes cultured from rat hippocampus. Journal of Neurophysiology. 65: 989-1002. PMID 2051214 DOI: 10.1152/JN.1991.65.4.989  0.663
1991 Sontheimer H, Ransom BR, Cornell-Bell AH, Black JA, Waxman SG. Na(+)-current expression in rat hippocampal astrocytes in vitro: alterations during development. Journal of Neurophysiology. 65: 3-19. PMID 1999729 DOI: 10.1152/JN.1991.65.1.3  0.687
1991 Stys PK, Waxman SG, Ransom BR. Na(+)-Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian central nervous system white matter. Annals of Neurology. 30: 375-80. PMID 1952825 DOI: 10.1002/Ana.410300309  0.756
1991 Gordon TR, Kocsis JD, Waxman SG. TEA-sensitive potassium channels and inward rectification in regenerated rat sciatic nerve. Muscle & Nerve. 14: 640-6. PMID 1922170 DOI: 10.1002/mus.880140707  0.59
1991 Utzschneider DA, Kocsis JD, Waxman SG. Differential sensitivity to hypoxia of the peripheral versus central trajectory of primary afferent axons. Brain Research. 551: 136-41. PMID 1913145 DOI: 10.1016/0006-8993(91)90924-K  0.574
1991 Stys PK, Ransom BR, Waxman SG. Compound action potential of nerve recorded by suction electrode: a theoretical and experimental analysis. Brain Research. 546: 18-32. PMID 1855148 DOI: 10.1016/0006-8993(91)91154-S  0.732
1991 Sontheimer H, Minturn JE, Ransom BR, Black JA, Cornell-Bell AH, Waxman SG. Cell coupling is restricted to subpopulations of astrocytes cultured from rat hippocampus and optic nerve. Annals of the New York Academy of Sciences. 633: 592-6. PMID 1789588 DOI: 10.1111/j.1749-6632.1991.tb15672.x  0.667
1991 Stys PK, Waxman SG, Ransom BR. Reverse operation of the Na(+)-Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian CNS white matter. Annals of the New York Academy of Sciences. 639: 328-32. PMID 1785859 DOI: 10.1111/J.1749-6632.1991.Tb17321.X  0.734
1991 Minturn JE, Sontheimer H, Black JA, Angelides KJ, Ransom BR, Ritchie JM, Waxman SG. Membrane-associated sodium channels and cytoplasmic precursors in glial cells. Immunocytochemical, electrophysiological, and pharmacological studies. Annals of the New York Academy of Sciences. 633: 255-71. PMID 1724129 DOI: 10.1111/j.1749-6632.1991.tb15619.x  0.697
1991 Waxman SG, Ransom BR, Stys PK. Non-synaptic mechanisms of Ca(2+)-mediated injury in CNS white matter. Trends in Neurosciences. 14: 461-8. PMID 1722366 DOI: 10.1016/0166-2236(91)90046-W  0.753
1991 Sontheimer H, Minturn JE, Black JA, Ransom BR, Waxman SG. Two types of Na(+)-currents in cultured rat optic nerve astrocytes: changes with time in culture and with age of culture derivation. Journal of Neuroscience Research. 30: 275-87. PMID 1665865 DOI: 10.1002/jnr.490300202  0.707
1991 Birch BD, Kocsis JD, Di Gregorio F, Bhisitkul RB, Waxman SG. A voltage- and time-dependent rectification in rat dorsal spinal root axons. Journal of Neurophysiology. 66: 719-28. PMID 1661325 DOI: 10.1152/Jn.1991.66.3.719  0.583
1991 O'Regan MH, Kocsis JD, Waxman SG. Nimodipine and nifedipine enhance transmission at the Schaffer collateral CA1 pyramidal neuron synapse. Experimental Brain Research. 84: 224-8. PMID 1649768 DOI: 10.1007/BF00231778  0.52
1991 Black JA, Felts P, Smith KJ, Kocsis JD, Waxman SG. Distribution of sodium channels in chronically demyelinated spinal cord axons: immuno-ultrastructural localization and electrophysiological observations. Brain Research. 544: 59-70. PMID 1649663 DOI: 10.1016/0006-8993(91)90885-Y  0.578
1991 Ransom B, Waxman S, Stys P. The pathophysiology of anoxic injury in mammalian central white matter Journal of the Neurological Sciences. 106: 118. DOI: 10.1016/0022-510X(91)90237-2  0.546
1990 Waxman SG, Black JA, Duncan ID, Ransom BR. Macromolecular structure of axon membrane and action potential conduction in myelin deficient and myelin deficient heterozygote rat optic nerves. Journal of Neurocytology. 19: 11-28. PMID 2351992 DOI: 10.1007/BF01188436  0.693
1990 Stys PK, Ransom BR, Waxman SG, Davis PK. Role of extracellular calcium in anoxic injury of mammalian central white matter. Proceedings of the National Academy of Sciences of the United States of America. 87: 4212-6. PMID 2349231 DOI: 10.1073/Pnas.87.11.4212  0.751
1990 Eng DL, Gordon TR, Kocsis JD, Waxman SG. Current-clamp analysis of a time-dependent rectification in rat optic nerve. The Journal of Physiology. 421: 185-202. PMID 2348391 DOI: 10.1113/jphysiol.1990.sp017940  0.589
1990 Sontheimer H, Minturn JE, Black JA, Waxman SG, Ransom BR. Specificity of cell-cell coupling in rat optic nerve astrocytes in vitro. Proceedings of the National Academy of Sciences of the United States of America. 87: 9833-7. PMID 2263634 DOI: 10.1073/PNAS.87.24.9833  0.674
1990 Waxman SG, Davis PK, Black JA, Ransom BR. Anoxic injury of mammalian central white matter: decreased susceptibility in myelin-deficient optic nerve. Annals of Neurology. 28: 335-40. PMID 2241117 DOI: 10.1002/ana.410280306  0.689
1990 Ransom BR, Stys PK, Waxman SG. The pathophysiology of anoxic injury in central nervous system white matter. Stroke; a Journal of Cerebral Circulation. 21: III52-7. PMID 2237986  0.745
1990 Stys PK, Ransom BR, Waxman SG. Effects of polyvalent cations and dihydropyridine calcium channel blockers on recovery of CNS white matter from anoxia. Neuroscience Letters. 115: 293-9. PMID 2234507 DOI: 10.1016/0304-3940(90)90471-K  0.76
1990 Elmer LW, Black JA, Waxman SG, Angelides KJ. The voltage-dependent sodium channel in mammalian CNS and PNS: antibody characterization and immunocytochemical localization. Brain Research. 532: 222-31. PMID 2178033 DOI: 10.1016/0006-8993(90)91763-7  0.375
1990 Ritchie JM, Black JA, Waxman SG, Angelides KJ. Sodium channels in the cytoplasm of Schwann cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 9290-4. PMID 2174558 DOI: 10.1073/pnas.87.23.9290  0.382
1990 Gordon TR, Kocsis JD, Waxman SG. Electrogenic pump (Na+/K(+)-ATPase) activity in rat optic nerve. Neuroscience. 37: 829-37. PMID 2174135 DOI: 10.1016/0306-4522(90)90112-H  0.572
1990 Minturn JE, Black JA, Angelides KJ, Waxman SG. Sodium channel expression detected with antibody 7493 in A2B5+ and A2B5- astrocytes from rat optic nerve in vitro. Glia. 3: 358-67. PMID 2172163 DOI: 10.1002/glia.440030507  0.373
1990 Bhisitkul RB, Kocsis JD, Gordon TR, Waxman SG. Trophic influence of the distal nerve segment on GABAA receptor expression in axotomized adult sensory neurons. Experimental Neurology. 109: 273-8. PMID 2170161 DOI: 10.1016/S0014-4886(05)80017-2  0.556
1990 Ransom BR, Waxman SG, Davis PK. Anoxic injury of CNS white matter: protective effect of ketamine. Neurology. 40: 1399-403. PMID 2168024 DOI: 10.1212/WNL.40.9.1399  0.663
1990 O'Regan MH, Kocsis JD, Waxman SG. Depolarization-dependent actions of dihydropyridines on synaptic transmission in the in vitro rat hippocampus. Brain Research. 527: 181-91. PMID 1701335 DOI: 10.1016/0006-8993(90)91136-5  0.524
1990 Black JA, Kocsis JD, Waxman SG. Ion channel organization of the myelinated fiber. Trends in Neurosciences. 13: 48-54. PMID 1690930 DOI: 10.1016/0166-2236(90)90068-L  0.579
1989 Bowe CM, Hildebrand C, Kocsis JD, Waxman SG. Morphological and physiological properties of neurons after long-term axonal regeneration: observations on chronic and delayed sequelae of peripheral nerve injury. Journal of the Neurological Sciences. 91: 259-92. PMID 2769297 DOI: 10.1016/0022-510X(89)90057-9  0.58
1989 Friedman B, Black JA, Hockfield S, Waxman SG, Ransom BR. Antigenic abnormalities in fiber tract astrocytes of myelin-deficient rats: an immunocytochemical study in the olfactory cortex. Developmental Neuroscience. 11: 99-111. PMID 2743882 DOI: 10.1159/000111891  0.673
1989 Black JA, Friedman B, Waxman SG, Elmer LW, Angelides KJ. Immuno-ultrastructural localization of sodium channels at nodes of Ranvier and perinodal astrocytes in rat optic nerve. Proceedings of the Royal Society of London. Series B, Biological Sciences. 238: 39-51. PMID 2574468 DOI: 10.1098/rspb.1989.0065  0.377
1989 Gordon TR, Kocsis JD, Waxman SG. Pharmacological sensitivities of two afterhyperpolarizations in rat optic nerve. Brain Research. 502: 252-7. PMID 2555026 DOI: 10.1016/0006-8993(89)90620-3  0.547
1989 Black JA, Waxman SG, Friedman B, Elmer LW, Angelides KJ. Sodium channels in astrocytes of rat optic nerve in situ: immuno-electron microscopic studies. Glia. 2: 353-69. PMID 2553601 DOI: 10.1002/glia.440020508  0.376
1989 Waxman SG, Black JA, Kocsis JD, Ritchie JM. Low density of sodium channels supports action potential conduction in axons of neonatal rat optic nerve. Proceedings of the National Academy of Sciences of the United States of America. 86: 1406-10. PMID 2537496 DOI: 10.1073/Pnas.86.4.1406  0.588
1989 Friedman B, Hockfield S, Black JA, Woodruff KA, Waxman SG. In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, rip. Glia. 2: 380-90. PMID 2530173 DOI: 10.1002/glia.440020510  0.308
1988 Waxman SG, Black JA. Unmyelinated and myelinated axon membrane from rat corpus callosum: differences in macromolecular structure Brain Research. 453: 337-343. PMID 3401771 DOI: 10.1016/0006-8993(88)90174-6  0.315
1988 Black JA, Fields RD, Waxman SG. Macromolecular structure of axonal membrane in the optic nerve of the jimpy mouse. Journal of Neuropathology and Experimental Neurology. 47: 588-98. PMID 3171604 DOI: 10.1097/00005072-198811000-00002  0.334
1988 Black JA, Waxman SG. The perinodal astrocyte Glia. 1: 169-183. PMID 2976037 DOI: 10.1002/glia.440010302  0.334
1988 Eng DL, Gordon TR, Kocsis JD, Waxman SG. Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibers. Journal of Neurophysiology. 60: 2168-79. PMID 2853208 DOI: 10.1152/Jn.1988.60.6.2168  0.585
1988 Gordon TR, Kocsis JD, Waxman SG. Evidence for the presence of two types of potassium channels in the rat optic nerve. Brain Research. 447: 1-9. PMID 2454699 DOI: 10.1016/0006-8993(88)90959-6  0.59
1987 Fields RD, Black JA, Waxman SG. Filipin-cholesterol binding in CNS axons prior to myelination: evidence for microheterogeneity in premyelinated axolemma. Brain Research. 404: 21-32. PMID 3567567 DOI: 10.1016/0006-8993(87)91351-5  0.307
1987 Bowe CM, Kocsis JD, Waxman SG. The association of the supernormal period and the depolarizing afterpotential in myelinated frog and rat sciatic nerve. Neuroscience. 21: 585-93. PMID 3497361 DOI: 10.1016/0306-4522(87)90144-8  0.56
1987 Black JA, Waxman SG, Smith ME. Macromolecular structure of axonal membrane during acute experimental allergic encephalomyelitis in rat and guinea pig spinal cord. Journal of Neuropathology and Experimental Neurology. 46: 167-84. PMID 3493331 DOI: 10.1097/00005072-198703000-00005  0.317
1987 Davis PK, Carlini WG, Ransom BR, Black JA, Waxman SG. Carbonic anhydrase activity develops postnatally in the rat optic nerve. Brain Research. 428: 291-8. PMID 3103868 DOI: 10.1016/0165-3806(87)90126-X  0.682
1987 Bowe CM, Kocsis JD, Targ EF, Waxman SG. Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers. Annals of Neurology. 22: 264-8. PMID 2821876 DOI: 10.1002/ana.410220212  0.561
1987 Bowe CM, Kocsis JD, Waxman SG, Hildebrand C. Physiological properties of regenerated rat sciatic nerve following lesions at different postnatal ages. Brain Research. 431: 123-31. PMID 2441822 DOI: 10.1016/0165-3806(87)90201-X  0.534
1987 Kocsis JD, Waxman SG. Ionic channel organization of normal and regenerating mammalian axons. Progress in Brain Research. 71: 89-101. PMID 2438722 DOI: 10.1016/S0079-6123(08)61816-6  0.563
1987 Kocsis JD, Eng DL, Gordon TR, Waxman SG. Functional differences between 4-aminopyridine and tetraethylammonium-sensitive potassium channels in myelinated axons. Neuroscience Letters. 75: 193-8. PMID 2437499 DOI: 10.1016/0304-3940(87)90296-5  0.603
1987 Hildebrand C, Kocsis JD, Berglund S, Waxman SG. Myelin sheath remodelling in regenerated rat sciatic nerve Pain. 28: 275. DOI: 10.1016/0304-3959(87)90138-2  0.534
1986 Black JA, Waxman SG, Sims TJ, Gilmore SA. Effects of delayed myelination by oligodendrocytes and Schwann cells on the macromolecular structure of axonal membrane in rat spinal cord. Journal of Neurocytology. 15: 745-61. PMID 3819778 DOI: 10.1007/BF01625192  0.343
1986 Kocsis JD, Bowe CM, Waxman SG. Different effects of 4-aminopyridine on sensory and motor fibers: pathogenesis of paresthesias. Neurology. 36: 117-20. PMID 3001584 DOI: 10.1212/WNL.36.1.117  0.518
1986 Kocsis JD, Gordon TR, Waxman SG. Mammalian optic nerve fibers display two pharmacologically distinct potassium channels. Brain Research. 383: 357-61. PMID 2429732 DOI: 10.1016/0006-8993(86)90040-5  0.563
1986 Fields RD, Black JA, Bowe CM, Kocsis JD, Waxman SG. Differences in intramembranous particle distribution in the paranodal axolemma are not associated with functional differences of dorsal and ventral roots. Neuroscience Letters. 67: 13-8. PMID 2425295 DOI: 10.1016/0304-3940(86)90200-4  0.56
1986 Black JA, Waxman SG. Molecular structure of the axolemma of developing axons following altered gliogenesis in rat optic nerve Developmental Biology. 115: 301-312. PMID 2423398 DOI: 10.1016/0012-1606(86)90251-4  0.327
1985 Waxman SG, Anderson MJ. Generation of electromotor neurons in Sternarchus albifrons: differences between normally growing and regenerating spinal cord. Developmental Biology. 112: 338-44. PMID 4076546 DOI: 10.1016/0012-1606(85)90404-X  0.329
1985 Anderson MJ, Waxman SG. Neurogenesis in tissue cultures of adult teleost spinal cord. Brain Research. 352: 203-12. PMID 4027666 DOI: 10.1016/0165-3806(85)90107-5  0.324
1985 Sims TJ, Waxman SG, Black JA, Gilmore SA. Perinodal astrocytic processes at nodes of Ranvier in developing normal and glial cell deficient rat spinal cord. Brain Research. 337: 321-31. PMID 4027576 DOI: 10.1016/0006-8993(85)90069-1  0.336
1985 Black JA, Sims TJ, Waxman SG, Gilmore SA. Membrane ultrastructure of developing axons in glial cell deficient rat spinal cord. Journal of Neurocytology. 14: 79-104. PMID 4009213 DOI: 10.1007/BF01150264  0.323
1985 Anderson MJ, Waxman SG. Neurogenesis in adult vertebrate spinal cord in situ and in vitro: a new model system. Annals of the New York Academy of Sciences. 457: 213-33. PMID 3913365 DOI: 10.1111/j.1749-6632.1985.tb20807.x  0.332
1985 Black JA, Waxman SG, Hildebrand C. Axo-glial relations in the retina-optic nerve junction of the adult rat: freeze-fracture observations on axon membrane structure Journal of Neurocytology. 14: 887-907. PMID 3831245 DOI: 10.1007/BF01224803  0.323
1985 Waxman SG, Black JA. Membrane structure of vesiculotubular complexes in developing axons in rat optic nerve: Freeze-fracture evidence for sequential membrane assembly Proceedings of the Royal Society of London - Biological Sciences. 225: 357-363. PMID 2865731 DOI: 10.1098/rspb.1985.0066  0.301
1985 Hildebrand C, Kocsis JD, Berglund S, Waxman SG. Myelin sheath remodelling in regenerated rat sciatic nerve. Brain Research. 358: 163-70. PMID 2416385 DOI: 10.1016/0006-8993(85)90960-6  0.539
1985 Waxman SG, Kocsis JD, Eng DL. Ligature-induced injury in peripheral nerve: electrophysiological observations on changes in action potential characteristics following blockade of potassium conductance. Muscle & Nerve. 8: 85-92. PMID 2414652 DOI: 10.1002/mus.880080202  0.58
1985 Bowe CM, Kocsis JD, Waxman SG. Differences between mammalian ventral and dorsal spinal roots in response to blockade of potassium channels during maturation. Proceedings of the Royal Society of London. Series B, Biological Sciences. 224: 355-66. PMID 2410932 DOI: 10.1098/Rspb.1985.0037  0.591
1985 Waxman SG, Ritchie JM. Organization of ion channels in the myelinated nerve fiber. Science (New York, N.Y.). 228: 1502-7. PMID 2409596 DOI: 10.1126/SCIENCE.2409596  0.37
1985 Ransom BR, Yamate CL, Black JA, Waxman SG. Rat optic nerve: disruption of gliogenesis with 5-azacytidine during early postnatal development. Brain Research. 337: 41-9. PMID 2408709 DOI: 10.1016/0006-8993(85)91607-5  0.694
1984 Waxman SG, Wood SL. Impulse conduction in inhomogeneous axons: Effects of variation in voltage-sensitive ionic conductances on invasion of demyelinated axon segments and preterminal fibers Brain Research. 294: 111-122. PMID 6697227 DOI: 10.1016/0006-8993(84)91314-3  0.346
1984 Black JA, Waxman SG, Hildebrand C. Membrane specialization and axo-glial association in the rat retinal nerve fibre layer: freeze-fracture observations Journal of Neurocytology. 13: 417-430. PMID 6481406 DOI: 10.1007/BF01148332  0.318
1984 Anderson MJ, Swanson KA, Waxman SG, Eng LF. Glial fibrillary acidic protein in regenerating teleost spinal cord. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 32: 1099-106. PMID 6481149 DOI: 10.1177/32.10.6481149  0.306
1984 Waxman SG, Black JA, Foster RE. Ontogenesis of the axolemma and axoglial relationships in myelinated fibers: electrophysiological and freeze-fracture correlates of membrane plasticity. International Review of Neurobiology. 24: 433-84. PMID 6360938 DOI: 10.1016/S0074-7742(08)60226-3  0.315
1983 Black JA, Foster RE, Waxman SG. Rat optic nerve: freeze-fracture studies during development of myelinated axons. Brain Research. 250: 1-20. PMID 7139310 DOI: 10.1016/0006-8993(82)90948-9  0.306
1983 Malenka RC, Kocsis JD, Waxman SG. The supernormal period of the cerebellar parallel fibers effects of [Ca2+]o and [K+]o. PflüGers Archiv : European Journal of Physiology. 397: 176-83. PMID 6878005 DOI: 10.1007/BF00584354  0.621
1983 Smith ME, Kocsis JD, Waxman SG. Myelin protein metabolism in demyelination and remyelination in the sciatic nerve. Brain Research. 270: 37-44. PMID 6871715 DOI: 10.1016/0006-8993(83)90789-8  0.538
1983 Kocsis JD, Malenka RC, Waxman SG. Effects of extracellular potassium concentration on the excitability of the parallel fibres of the rat cerebellum. The Journal of Physiology. 334: 225-44. PMID 6864558 DOI: 10.1113/jphysiol.1983.sp014491  0.611
1983 Anderson MJ, Waxman SG, Laufer M. Fine structure of regenerated ependyma and spinal cord in Sternarchus albifrons. The Anatomical Record. 205: 73-83. PMID 6837937 DOI: 10.1002/ar.1092050110  0.33
1983 Preston RJ, Waxman SG, Kocsis JD. Effects of 4-aminopyridine on rapidly and slowly conducting axons of rat corpus callosum. Experimental Neurology. 79: 808-20. PMID 6825765 DOI: 10.1016/0014-4886(83)90044-4  0.546
1983 Kocsis JD, Ruiz JA, Waxman SG. Maturation of mammalian myelinated fibers: changes in action-potential characteristics following 4-aminopyridine application. Journal of Neurophysiology. 50: 449-63. PMID 6310062 DOI: 10.1152/Jn.1983.50.2.449  0.517
1983 Kocsis JD, Waxman SG. Long-term regenerated nerve fibres retain sensitivity to potassium channel blocking agents. Nature. 304: 640-2. PMID 6308475 DOI: 10.1038/304640a0  0.572
1982 Waxman SG, Anderson MJ. Retrograde axon reaction following section of asynaptic nerve fibers Cell and Tissue Research. 223: 487-492. PMID 7093992 DOI: 10.1007/BF00218470  0.355
1982 Wood SL, Waxman SG, Kocsis JD. Conduction of trans of impulses in uniform myelinated fibers: computed dependence on stimulus frequency. Neuroscience. 7: 423-30. PMID 7078731 DOI: 10.1016/0306-4522(82)90276-7  0.503
1982 Foster RE, Connors BW, Waxman SG. Rat optic nerve: electrophysiological, pharmacological and anatomical studies during development. Brain Research. 255: 371-86. PMID 7066695 DOI: 10.1016/0165-3806(82)90005-0  0.616
1982 Kocsis JD, Waxman SG. Intra-axonal recordings in rat dorsal column axons: membrane hyperpolarization and decreased excitability precede the primary afferent depolarization. Brain Research. 238: 222-7. PMID 6282392 DOI: 10.1016/0006-8993(82)90787-9  0.577
1982 Kocsis JD, Waxman SG, Hildebrand C, Ruiz JA. Regenerating mammalian nerve fibres: changes in action potential waveform and firing characteristics following blockage of potassium conductance. Proceedings of the Royal Society of London. Series B, Biological Sciences. 217: 77-87. PMID 6131423 DOI: 10.1098/Rspb.1982.0095  0.577
1981 Swadlow HA, Waxman SG, Weyand TG. Effects of variations in temperature on impulse conduction along nonmyelinated axons in the mammalian brain. Experimental Neurology. 71: 383-9. PMID 7449905 DOI: 10.1016/0014-4886(81)90096-0  0.771
1981 Anderson MJ, Waxman SG. Morphology of regenerated spinal cord in Sternarchus albifrons Cell and Tissue Research. 219: 1-8. PMID 7285088 DOI: 10.1007/BF00210014  0.339
1981 Malenka RC, Kocsis JD, Ransom BR, Waxman SG. Modulation of parallel fiber excitability by postsynaptically mediated changes in extracellular potassium. Science (New York, N.Y.). 214: 339-41. PMID 7280695 DOI: 10.1126/Science.7280695  0.761
1981 Kocsis JD, Cummins KL, Waxman SG, Malenka RC. Impulse entrainment: computer simulations and studies on the parallel fibers of the cerebellum. Experimental Neurology. 72: 628-37. PMID 7238712 DOI: 10.1016/0014-4886(81)90011-X  0.62
1981 Kocsis JD, Malenka RC, Connors BW, Waxman SG, Cummins KL. Population response characteristics of fiber tracts in central white matter. Progress in Clinical and Biological Research. 52: 17-32. PMID 7232442  0.692
1981 Kocsis JD, Malenka RC, Waxman SG. Enhanced parallel fiber frequency-following after reduction of postsynaptic activity. Brain Research. 207: 321-31. PMID 6258738 DOI: 10.1016/0006-8993(81)90367-X  0.622
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