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Stephen G. Waxman - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
pain, ion channels
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Year Citation  Score
2021 Gualdani R, Yuan JH, Effraim PR, Di Stefano G, Truini A, Cruccu G, Dib-Hajj SD, Gailly P, Waxman SG. Trigeminal Neuralgia TRPM8 Mutation: Enhanced Activation, Basal [Ca] and Menthol Response. Neurology. Genetics. 7: e550. PMID 33977138 DOI: 10.1212/NXG.0000000000000550  0.64
2021 Xenakis MN, Kapetis D, Yang Y, Gerrits MM, Heijman J, Waxman SG, Lauria G, Faber CG, Westra RL, Lindsey PJ, Smeets HJ. Hydropathicity-based prediction of pain-causing NaV1.7 variants. Bmc Bioinformatics. 22: 212. PMID 33892629 DOI: 10.1186/s12859-021-04119-2  0.4
2021 Benson CA, Olson KL, Patwa S, Reimer ML, Bangalore L, Hill M, Waxman SG, Tan AM. Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury. Scientific Reports. 11: 7838. PMID 33837249 DOI: 10.1038/s41598-021-87476-5  0.84
2021 Xenakis MN, Kapetis D, Yang Y, Heijman J, Waxman SG, Lauria G, Faber CG, Smeets HJ, Lindsey PJ, Westra RL. Non-extensitivity and criticality of atomic hydropathicity around a voltage-gated sodium channel's pore: a modeling study. Journal of Biological Physics. PMID 33735400 DOI: 10.1007/s10867-021-09565-w  0.4
2021 Akin EJ, Alsaloum M, Higerd GP, Liu S, Zhao P, Dib-Hajj FB, Waxman SG, Dib-Hajj SD. Paclitaxel increases axonal localization and vesicular trafficking of Nav1.7. Brain : a Journal of Neurology. PMID 33734317 DOI: 10.1093/brain/awab113  0.68
2021 Honmou O, Yamashita T, Morita T, Oshigiri T, Hirota R, Iyama S, Kato J, Sasaki Y, Ishiai S, Ito YM, Namioka A, Namioka T, Nakazaki M, Kataoka-Sasaki Y, Onodera R, ... ... Waxman SG, et al. Intravenous infusion of auto serum-expanded autologous mesenchymal stem cells in spinal cord injury patients: 13 case series. Clinical Neurology and Neurosurgery. 203: 106565. PMID 33667953 DOI: 10.1016/j.clineuro.2021.106565  1
2021 Almomani R, Marchi M, Sopacua M, Lindsey P, Salvi E, de Koning B, Santoro S, Magri S, Smeets HJM, Boneschi FM, Malik RA, Ziegler D, Hoeijmakers JGJ, Bönhof G, Dib-Hajj S, ... Waxman SG, et al. Correction: Evaluation of molecular inversion probe versus TruSeq® custom methods for targeted next-generation sequencing. Plos One. 16: e0248250. PMID 33651841 DOI: 10.1371/journal.pone.0248250  0.48
2020 Chen L, Wimalasena NK, Shim J, Han C, Lee SI, Gonzalez-Cano R, Estacion M, Faber CG, Lauria G, Dib-Hajj SG, Woolf CJ, Waxman SG. Two independent mouse lines carrying the Nav1.7-I228M gain-of-function variant display DRG neuron hyperexcitability but a minimal pain phenotype. Pain. PMID 33323889 DOI: 10.1097/j.pain.0000000000002171  0.52
2020 Cheng X, Choi JS, Waxman SG, Dib-Hajj SD. Mini-review - Sodium channels and beyond in peripheral nerve disease: Modulation by cytokines and their effector protein kinases. Neuroscience Letters. 135446. PMID 33166641 DOI: 10.1016/j.neulet.2020.135446  0.64
2020 Reimer ML, Bangalore L, Waxman SG, Tan AM. Core principles for the implementation of the neurodata without borders data standard. Journal of Neuroscience Methods. 108972. PMID 33157146 DOI: 10.1016/j.jneumeth.2020.108972  0.84
2020 Alsaloum M, Higerd GP, Effraim PR, Waxman SG. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nature Reviews. Neurology. PMID 33110213 DOI: 10.1038/s41582-020-00415-2  0.36
2020 Toffano AA, Chiarot G, Zamuner S, Marchi M, Salvi E, Waxman SG, Faber CG, Lauria G, Giacometti A, Simeoni M. Computational pipeline to probe NaV1.7 gain-of-function variants in neuropathic painful syndromes. Scientific Reports. 10: 17930. PMID 33087732 DOI: 10.1038/s41598-020-74591-y  0.4
2020 Dong W, Jin SC, Allocco A, Zeng X, Sheth AH, Panchagnula S, Castonguay A, Lorenzo LÉ, Islam B, Brindle G, Bachand K, Hu J, Sularz A, Gaillard J, Choi J, ... ... Waxman SG, et al. Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia. Iscience. 23: 101552. PMID 33083721 DOI: 10.1016/J.Isci.2020.101552  0.48
2020 Almomani R, Marchi M, Sopacua M, Lindsey P, Salvi E, Koning B, Santoro S, Magri S, Smeets HJM, Martinelli Boneschi F, Malik RR, Ziegler D, Hoeijmakers JGJ, Bönhof G, Dib-Hajj S, ... Waxman SG, et al. Evaluation of molecular inversion probe versus TruSeq® custom methods for targeted next-generation sequencing. Plos One. 15: e0238467. PMID 32877464 DOI: 10.1371/journal.pone.0238467  0.48
2020 Chen L, Huang J, Benson C, Lankford KL, Zhao P, Carrara J, Tan AM, Kocsis JD, Waxman SG, Dib-Hajj SD. Sodium channel Nav1.6 in sensory neurons contributes to vincristine-induced allodynia. Brain : a Journal of Neurology. PMID 32830219 DOI: 10.1093/Brain/Awaa208  1
2020 McMahon KL, Tay B, Deuis JR, Tanaka BS, Peigneur S, Jin AH, Tytgat J, Waxman SG, Dib-Hajj SD, Vetter I, Schroeder CI. Pharmacological activity and NMR solution structure of the leech peptide HSTX-I. Biochemical Pharmacology. 114082. PMID 32524995 DOI: 10.1016/J.Bcp.2020.114082  0.64
2020 Xenakis MN, Kapetis D, Yang Y, Heijman J, Waxman SG, Lauria G, Faber CG, Smeets HJM, Westra RL, Lindsey P. Cumulative hydropathic topology of a voltage-gated sodium channel at atomic resolution. Proteins. PMID 32447794 DOI: 10.1002/prot.25951  0.4
2020 Benson CA, Fenrich KK, Olson KL, Patwa S, Bangalore L, Waxman SG, Tan AM. Dendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32371602 DOI: 10.1523/Jneurosci.2858-19.2020  0.84
2020 Labau JI, Estacion M, Tanaka BS, de Greef BT, Hoeijmakers JG, Geerts M, Gerrits MM, Smeets HJ, Faber CG, Merkies IS, Lauria G, Dib-Hajj SD, Waxman SG. Differential effect of lacosamide on Nav1.7 variants from responsive and non-responsive patients with small fibre neuropathy. Brain : a Journal of Neurology. PMID 32011655 DOI: 10.1093/Brain/Awaa016  0.64
2020 Chen L, Effraim P, Carrara J, Zhao P, Dib-Hajj FB, Dib-Hajj SD, Waxman SG. Pharmacological characterization of a rat Nav1.7 loss-of-function model with insensitivity to pain. Pain. PMID 31977939 DOI: 10.1097/j.pain.0000000000001807  0.64
2020 Di Stefano G, Yuan JH, Cruccu G, Waxman SG, Dib-Hajj SD, Truini A. Familial trigeminal neuralgia - a systematic clinical study with a genomic screen of the neuronal electrogenisome. Cephalalgia : An International Journal of Headache. 333102419897623. PMID 31928344 DOI: 10.1177/0333102419897623  0.64
2019 Patwa S, Benson CA, Dyer L, Olson KL, Bangalore L, Hill M, Waxman SG, Tan AM. Spinal cord motor neuron plasticity accompanies second-degree burn injury and chronic pain. Physiological Reports. 7: e14288. PMID 31858746 DOI: 10.14814/phy2.14288  0.84
2019 Lee SI, Hoeijmakers JGJ, Faber CG, Merkies ISJ, Lauria G, Waxman SG. The small fiber neuropathy NaV1.7 I228M mutation: impaired neurite integrity bioenergetic and mitotoxic mechanisms, and protection by dexpramipexole. Journal of Neurophysiology. PMID 31851560 DOI: 10.1152/jn.00360.2019  0.4
2019 Sizova DV, Huang J, Akin EJ, Estacion M, Gomis-Perez C, Waxman SG, Dib-Hajj SD. A 49-residue sequence motif in the C-terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane. The Journal of Biological Chemistry. PMID 31822564 DOI: 10.1074/Jbc.Ra119.011424  0.64
2019 Urru M, Muzzi M, Coppi E, Ranieri G, Buonvicino D, Camaioni E, Coppini R, Pugliese AM, Tanaka B, Estacion M, Waxman SG, Dib-Hajj SD, Chiarugi A. Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models. Pain. PMID 31815915 DOI: 10.1097/J.Pain.0000000000001774  0.64
2019 Akin EJ, Higerd GP, Mis MA, Tanaka BS, Adi T, Liu S, Dib-Hajj FB, Waxman SG, Dib-Hajj SD. Building sensory axons: Delivery and distribution of Na1.7 channels and effects of inflammatory mediators. Science Advances. 5: eaax4755. PMID 31681845 DOI: 10.1126/Sciadv.Aax4755  0.68
2019 Huang J, Estacion M, Zhao P, Dib-Hajj FB, Schulman B, Abicht A, Kurth I, Brockmann K, Waxman SG, Dib-Hajj SD. A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain. Frontiers in Neuroscience. 13: 918. PMID 31551682 DOI: 10.3389/Fnins.2019.00918  0.64
2019 Grubinska B, Chen L, Alsaloum M, Rampal N, Matson D, Yang C, Taborn K, Zhang M, Youngblood B, Liu D, Galbreath E, Allred S, Lepherd M, Ferrando R, Kornecook T, ... ... Waxman S, et al. [EXPRESS] Rat NaV1.7 loss-of-function genetic model: deficient nociceptive and neuropathic pain behavior with retained olfactory function and intra-epidermal nerve fibers. Molecular Pain. 1744806919881846. PMID 31550995 DOI: 10.1177/1744806919881846  0.48
2019 Effraim PR, Huang J, Lampert A, Stamboulian S, Zhao P, Black JA, Dib-Hajj SD, Waxman SG. Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner. Neurobiology of Pain (Cambridge, Mass.). 6: 100029. PMID 31223136 DOI: 10.1016/J.Ynpai.2019.100029  1
2019 Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I. Na 1.6 regulates excitability of mechanosensitive sensory neurons. The Journal of Physiology. PMID 31087362 DOI: 10.1113/Jp278148  0.64
2019 Alsaloum M, Estacion M, Almomani R, Gerrits M, Bönhof G, Ziegler D, Malik R, Ferdousi M, Lauria G, Merkies I, Faber C, Dib-Hajj S, Waxman S. [EXPRESS] A gain-of-function sodium channel β2 subunit mutation in painful diabetic neuropathy. Molecular Pain. 1744806919849802. PMID 31041876 DOI: 10.1177/1744806919849802  0.52
2019 Vrselja Z, Daniele SG, Silbereis J, Talpo F, Morozov YM, Sousa AMM, Tanaka BS, Skarica M, Pletikos M, Kaur N, Zhuang ZW, Liu Z, Alkawadri R, Sinusas AJ, Latham SR, ... Waxman SG, et al. Restoration of brain circulation and cellular functions hours post-mortem. Nature. 568: 336-343. PMID 30996318 DOI: 10.1038/S41586-019-1099-1  0.36
2019 Waxman SG, Dib-Hajj SD. The Two Sides of Na1.7: Painful and Painless Channelopathies. Neuron. 101: 765-767. PMID 30844393 DOI: 10.1016/j.neuron.2019.02.016  0.64
2019 Dib-Hajj SD, Waxman SG. Sodium Channels in Human Pain Disorders: Genetics and Pharmacogenomics. Annual Review of Neuroscience. PMID 30702961 DOI: 10.1146/annurev-neuro-070918-050144  0.64
2019 Bennett DL, Clark AJ, Huang J, Waxman SG, Dib-Hajj SD. The Role of Voltage-Gated Sodium Channels in Pain Signaling. Physiological Reviews. 99: 1079-1151. PMID 30672368 DOI: 10.1152/Physrev.00052.2017  0.64
2019 de Greef BTA, Hoeijmakers JGJ, Geerts M, Oakes M, Church TJE, Waxman SG, Dib-Hajj SD, Faber CG, Merkies ISJ. Lacosamide in patients with Nav1.7 mutations-related small fibre neuropathy: a randomized controlled trial. Brain : a Journal of Neurology. PMID 30649227 DOI: 10.1093/brain/awy329  0.64
2018 Geha P, Schulman BR, Dib-Hajj SD, Waxman SG. Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning. Neurobiology of Pain (Cambridge, Mass.). 3: 8-14. PMID 31080911 DOI: 10.1016/J.Ynpai.2018.01.002  0.64
2018 Sopacua M, Hoeijmakers JGJ, Merkies ISJ, Lauria G, Waxman SG, Faber CG. Small-fiber neuropathy: Expanding the clinical pain universe. Journal of the Peripheral Nervous System : Jpns. PMID 30569495 DOI: 10.1111/jns.12298  0.4
2018 Eijkenboom I, Sopacua M, Hoeijmakers JGJ, de Greef BTA, Lindsey P, Almomani R, Marchi M, Vanoevelen J, Smeets HJM, Waxman SG, Lauria G, Merkies ISJ, Faber CG, Gerrits MM. Yield of peripheral sodium channels gene screening in pure small fibre neuropathy. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 30554136 DOI: 10.1136/jnnp-2018-319042  0.4
2018 Hashimoto-Torii K, Sasaki M, Chang YW, Hwang H, Waxman SG, Kocsis JD, Rakic P, Torii M. Detection of local and remote cellular damage caused by spinal cord and peripheral nerve injury using a heat shock signaling reporter system. Ibro Reports. 5: 91-98. PMID 30480161 DOI: 10.1016/J.Ibror.2018.11.003  1
2018 Mis MA, Yang Y, Tanaka BS, Gomis-Perez C, Liu S, Dib-Hajj F, Adi T, Garcia-Milian R, Schulman BR, Dib-Hajj SD, Waxman SG. Resilience to Pain: A Peripheral Component Identified using induced Pluripotent Stem Cells and Dynamic Clamp. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30459225 DOI: 10.1523/Jneurosci.2433-18.2018  0.68
2018 Arthur L, Keen K, Verriotis M, Peters J, Kelly A, Howard RF, Dib-Hajj SD, Waxman SG, Walker SM. Pediatric Erythromelalgia and SCN9A Mutations: Systematic Review and Single-Center Case Series. The Journal of Pediatrics. PMID 30416015 DOI: 10.1016/j.jpeds.2018.10.024  0.64
2018 Adi T, Estacion M, Schulman BR, Vernino S, Dib-Hajj S, Waxman S. [EXPRESS] A novel gain-of-function Na1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy. Molecular Pain. 1744806918815007. PMID 30392441 DOI: 10.1177/1744806918815007  0.52
2018 Hofmann L, Hose D, Grießhammer A, Blum R, Döring F, Dib-Hajj S, Waxman S, Sommer C, Wischmeyer E, Üçeyler N. Characterization of small fiber pathology in a mouse model of Fabry disease. Elife. 7. PMID 30328411 DOI: 10.7554/eLife.39300  0.48
2018 Eijkenboom I, Sopacua M, Otten ABC, Gerrits MM, Hoeijmakers JGJ, Waxman SG, Lombardi R, Lauria G, Merkies ISJ, Smeets HJM, Faber CG, Vanoevelen JM. Expression of pathogenic SCN9A mutations in the zebrafish: A model to study small fiber neuropathy. Experimental Neurology. PMID 30316835 DOI: 10.1016/j.expneurol.2018.10.008  0.4
2018 Pappalardo LW, Samad OA, Liu S, Zwinger PJ, Black JA, Waxman SG. Nav1.5 in astrocytes plays a sex-specific role in clinical outcomes in a mouse model of multiple sclerosis. Glia. PMID 30194875 DOI: 10.1002/glia.23470  0.88
2018 Hoffstaetter LJ, Mastrotto M, Merriman DK, Dib-Hajj SD, Waxman SG, Bagriantsev SN, Gracheva EO. Somatosensory Neurons Enter a State of Altered Excitability during Hibernation. Current Biology : Cb. PMID 30174191 DOI: 10.1016/J.Cub.2018.07.020  0.64
2018 Han C, Themistocleous AC, Estacion M, Dib-Hajj FB, Blesneac I, Macala L, Fratter C, Bennett DL, Waxman SG, Dib-Hajj SD. The novel activity of carbamazepine as an activation modulator extends from NaV1.7 mutations to the NaV1.8-S242T mutant channel from a patient with painful diabetic neuropathy. Molecular Pharmacology. PMID 30135145 DOI: 10.1124/mol.118.113076  0.64
2018 Dash B, Dib-Hajj SD, Waxman SG. Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits. Molecular Brain. 11: 45. PMID 30086768 DOI: 10.1186/s13041-018-0388-1  0.64
2018 Nettuwakul C, Praditsap O, Sawasdee N, Rungroj N, Ruamyod K, Watanapa WB, Junking M, Sangnual S, Sritippayawan S, Cheunsuchon B, Chuawattana D, Rojsatapong S, Chaowagul W, Dib-Hajj SD, Waxman SG, et al. Loss-of-function mutations of SCN10A encoding Na1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease. Scientific Reports. 8: 10453. PMID 29992996 DOI: 10.1038/s41598-018-28623-3  0.64
2018 Guo Y, Benson C, Hill M, Henry S, Effraim P, Waxman S, Dib-Hajj S, Tan AM. [EXPRESS] THERAPEUTIC POTENTIAL OF PAK1 INHIBITION FOR PAIN ASSOCIATED WITH CUTANEOUS BURN INJURY. Molecular Pain. 1744806918788648. PMID 29956587 DOI: 10.1177/1744806918788648  0.84
2018 Dash B, Han C, Waxman S, Dib-Hajj S. Non-muscle myosin II isoforms interact with sodium channel alpha subunits. Molecular Pain. 1744806918788638. PMID 29956586 DOI: 10.1177/1744806918788638  0.48
2018 Mis MA, Rogers MF, Jeffries AR, Wilbrey AL, Chen L, Yang Y, Dib-Hajj S, Waxman SG, Stevens EB, Randall AD. Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons. Aging Cell. e12795. PMID 29943484 DOI: 10.1111/acel.12795  0.48
2018 Li Y, Zhu T, Yang H, Dib-Hajj S, Waxman S, Yu Y, Xu TL, Cheng X. [EXPRESS] Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner. Molecular Pain. 1744806918782229. PMID 29790812 DOI: 10.1177/1744806918782229  0.48
2018 Chen L, Huang J, Zhao P, Persson AK, Dib-Hajj FB, Cheng X, Tan A, Waxman SG, Dib-Hajj SD. Conditional knockout of Na1.6 in adult mice ameliorates neuropathic pain. Scientific Reports. 8: 3845. PMID 29497094 DOI: 10.1038/S41598-018-22216-W  0.64
2018 Huang J, Mis MA, Tanaka B, Adi T, Estacion M, Liu S, Walker S, Dib-Hajj SD, Waxman SG. Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation. Scientific Reports. 8: 1811. PMID 29379075 DOI: 10.1038/S41598-018-20221-7  0.68
2018 Yang Y, Mis MA, Estacion M, Dib-Hajj SD, Waxman SG. NaV1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine. Trends in Pharmacological Sciences. PMID 29370938 DOI: 10.1016/j.tips.2017.11.010  0.64
2018 Hofmann L, Hose D, Grießhammer A, Blum R, Döring F, Dib-Hajj S, Waxman S, Sommer C, Wischmeyer E, Üçeyler N. Author response: Characterization of small fiber pathology in a mouse model of Fabry disease Elife. DOI: 10.7554/Elife.39300.014  0.48
2017 Waxman SG, Black JA. Ode to Glia: A Tribute to Bruce Ransom. Neurochemical Research. 42: 2442. PMID 28921457 DOI: 10.1007/s11064-017-2368-8  0.88
2017 Yang Y, Adi T, Effraim P, Chen L, Dib-Hajj SD, Waxman SG. Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal-induced hyperexcitability of sensory neurons due to Nav1.7 mutation I234T. British Journal of Pharmacology. PMID 28658526 DOI: 10.1111/bph.13935  0.64
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, et al. Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 46816. PMID 28548111 DOI: 10.1038/Srep46816  0.64
2017 Huang J, Vanoye CG, Cutts A, Goldberg YP, Dib-Hajj SD, Cohen CJ, Waxman SG, George AL. Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability. The Journal of Clinical Investigation. PMID 28530638 DOI: 10.1172/Jci92373  0.64
2017 Tanaka BS, Nguyen PT, Zhou EY, Yang Y, Yarov-Yarovoy V, Dib-Hajj SD, Waxman SG. Gain-of-Function Mutation of a Voltage-Gated Sodium Channel NaV1.7 Associated with Peripheral Pain and Impaired Limb Development. The Journal of Biological Chemistry. PMID 28381558 DOI: 10.1074/Jbc.M117.778779  0.64
2017 Cao XC, Pappalardo LW, Waxman SG, Tan AM. Dendritic spine dysgenesis in superficial dorsal horn sensory neurons after spinal cord injury. Molecular Pain. 13: 1744806916688016. PMID 28326929 DOI: 10.1177/1744806916688016  0.84
2017 Dib-Hajj SD, Geha P, Waxman SG. Sodium channels in pain disorders: pathophysiology and prospects for treatment. Pain. PMID 28240647 DOI: 10.1097/J.Pain.0000000000000854  0.64
2017 Kapetis D, Sassone J, Yang Y, Galbardi B, Xenakis MN, Westra RL, Szklarczyk R, Lindsey P, Faber CG, Gerrits M, Merkies IS, Dib-Hajj SD, Mantegazza M, Waxman SG, Lauria G, et al. Network topology of NaV1.7 mutations in sodium channel-related painful disorders. Bmc Systems Biology. 11: 28. PMID 28235406 DOI: 10.1186/S12918-016-0382-0  0.64
2017 Zakrzewska JM, Palmer J, Morisset V, Giblin GM, Obermann M, Ettlin DA, Cruccu G, Bendtsen L, Estacion M, Derjean D, Waxman SG, Layton G, Gunn K, Tate S. Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial. The Lancet. Neurology. PMID 28216232 DOI: 10.1016/S1474-4422(17)30005-4  0.52
2017 Estacion M, Waxman SG. Nonlinear effects of hyperpolarizing shifts in activation of mutant NaV1.7 channels on resting membrane potential. Journal of Neurophysiology. jn.00898.2016. PMID 28148645 DOI: 10.1152/jn.00898.2016  0.52
2017 Torii M, Sasaki M, Chang YW, Ishii S, Waxman SG, Kocsis JD, Rakic P, Hashimoto-Torii K. Detection of vulnerable neurons damaged by environmental insults in utero. Proceedings of the National Academy of Sciences of the United States of America. PMID 28123061 DOI: 10.1073/Pnas.1620641114  1
2017 Asiedu MN, Han C, Dib-Hajj SD, Waxman SG, Price TJ, Dussor G. The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development. Plos One. 12: e0169882. PMID 28118359 DOI: 10.1371/Journal.Pone.0169882  0.64
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/Srep40883  0.64
2017 Martinelli-Boneschi F, Colombi M, Castori M, Devigili G, Eleopra R, Malik RA, Ritelli M, Zoppi N, Dordoni C, Sorosina M, Grammatico P, Fadavi H, Gerrits MM, Almomani R, Faber CG, ... ... Waxman SG, et al. COL6A5 variants in familial neuropathic chronic itch. Brain : a Journal of Neurology. PMID 28073787 DOI: 10.1093/brain/aww343  0.64
2016 Lee SJ, Kim DH, Hahn SJ, Waxman SG, Choi JS. Mechanism of inhibition by chlorpromazine of the human pain threshold sodium channel, Nav1.7. Neuroscience Letters. PMID 28017662 DOI: 10.1016/j.neulet.2016.12.051  0.6
2016 Rolyan H, Liu S, Hoeijmakers JG, Faber CG, Merkies IS, Lauria G, Black JA, Waxman SG. A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels. Molecular Pain. 12. PMID 27821467 DOI: 10.1177/1744806916674472  0.88
2016 Duan G, Han C, Wang Q, Guo S, Zhang Y, Ying Y, Huang P, Zhang L, Macala L, Shah P, Zhang M, Li N, Dib-Hajj SD, Waxman SG, Zhang X. A SCN10A SNP biases human pain sensitivity. Molecular Pain. 12. PMID 27590072 DOI: 10.1177/1744806916666083  0.64
2016 Han C, Yang Y, Te Morsche RH, Drenth JP, Politei JM, Waxman SG, Dib-Hajj SD. Familial gain-of-function Nav1.9 mutation in a painful channelopathy. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27503742 DOI: 10.1136/jnnp-2016-313804  0.64
2016 Tanaka BS, Zhao P, Dib-Hajj FB, Morisset V, Tate S, Waxman SG, Dib-Hajj SD. A gain-of-function mutation in Nav1.6 in a case of trigeminal neuralgia. Molecular Medicine (Cambridge, Mass.). 22. PMID 27496104 DOI: 10.2119/Molmed.2016.00131  0.64
2016 Yang Y, Huang J, Mis MA, Estacion M, Macala L, Shah P, Schulman BR, Horton DB, Dib-Hajj SD, Waxman SG. Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7511-22. PMID 27413160 DOI: 10.1523/Jneurosci.0462-16.2016  1
2016 Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, et al. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia. Science Translational Medicine. 8: 335ra56. PMID 27099175 DOI: 10.1126/Scitranslmed.Aad7653  1
2016 Geha P, Yang Y, Estacion M, Schulman BR, Tokuno H, Apkarian AV, Dib-Hajj SD, Waxman SG. Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling. Jama Neurology. PMID 27088781 DOI: 10.1001/Jamaneurol.2016.0389  1
2016 Persson AK, Hoeijmakers JG, Estacion M, Black JA, Waxman SG. Sodium Channels, Mitochondria, and Axonal Degeneration in Peripheral Neuropathy. Trends in Molecular Medicine. PMID 27085813 DOI: 10.1016/j.molmed.2016.03.008  0.88
2016 Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, ... ... Waxman SG, et al. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. Plos One. 11: e0152405. PMID 27050761 DOI: 10.1371/Journal.Pone.0152405  1
2016 Zhao P, Hill M, Liu S, Chen L, Bangalore L, Waxman SG, Tan AM. Dendritic Spine Remodeling Following Early and Late Rac1-Inhibition after Spinal Cord Injury: Evidence for a Pain Biomarker. Journal of Neurophysiology. jn.01057.2015. PMID 26936986 DOI: 10.1152/jn.01057.2015  0.84
2016 McDonnell A, Schulman B, Ali Z, Dib-Hajj SD, Brock F, Cobain S, Mainka T, Vollert J, Tarabar S, Waxman SG. Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile. Brain : a Journal of Neurology. PMID 26920677 DOI: 10.1093/Brain/Aww007  1
2016 Pappalardo LW, Black JA, Waxman SG. Sodium channels in astroglia and microglia. Glia. PMID 26919466 DOI: 10.1002/glia.22967  0.88
2016 Han C, Huang J, Waxman SG. Sodium channel Nav1.8: Emerging links to human disease. Neurology. PMID 26747884 DOI: 10.1212/Wnl.0000000000002333  1
2015 Dib-Hajj SD, Waxman SG. Diversity of composition and function of sodium channels in peripheral sensory neurons. Pain. 156: 2406-7. PMID 26580678 DOI: 10.1097/j.pain.0000000000000353  0.64
2015 Doppler K, Appeltshauser L, Krämer HH, Ng JK, Meinl E, Villmann C, Brophy P, Dib-Hajj SD, Waxman SG, Weishaupt A, Sommer C. Correction: Contactin-1 and Neurofascin-155/-186 Are Not Targets of Auto-Antibodies in Multifocal Motor Neuropathy. Plos One. 10: e0137443. PMID 26317434 DOI: 10.1371/journal.pone.0137443  0.64
2015 Dib-Hajj SD, Black JA, Waxman SG. NaV1.9: a sodium channel linked to human pain. Nature Reviews. Neuroscience. 16: 511-9. PMID 26243570 DOI: 10.1038/nrn3977  1
2015 Doppler K, Appeltshauser L, Krämer HH, Ng JK, Meinl E, Villmann C, Brophy P, Dib-Hajj SD, Waxman SG, Weishaupt A, Sommer C. Contactin-1 and Neurofascin-155/-186 Are Not Targets of Auto-Antibodies in Multifocal Motor Neuropathy. Plos One. 10: e0134274. PMID 26218529 DOI: 10.1371/Journal.Pone.0134274  0.84
2015 Estacion M, Vohra BP, Liu S, Hoeijmakers JG, Faber CG, Merkies IS, Lauria G, Black JA, Waxman SG. Ca2+ toxicity due to reverse Na+-Ca2+ exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutation. Journal of Neurophysiology. jn.00195.2015. PMID 26156380 DOI: 10.1152/jn.00195.2015  1
2015 Tan AM, Samad OA, Dib-Hajj SD, Waxman SG. Virus-Mediated Knockdown of Nav1.3 in Dorsal Root Ganglia of STZ-Induced Diabetic Rats Alleviates Tactile Allodynia. Molecular Medicine (Cambridge, Mass.). 21: 544-52. PMID 26101954 DOI: 10.2119/molmed.2015.00063  1
2015 Rice FL, Albrecht PJ, Wymer JP, Black JA, Merkies IS, Faber CG, Waxman SG. Sodium channel Nav1.7 in vascular myocytes, endothelium, and innervating axons in human skin. Molecular Pain. 11: 26. PMID 25957174 DOI: 10.1186/S12990-015-0024-3  0.88
2015 Akin EJ, Solé L, Dib-Hajj SD, Waxman SG, Tamkun MM. Preferential targeting of Nav1.6 voltage-gated Na+ Channels to the axon initial segment during development. Plos One. 10: e0124397. PMID 25874799 DOI: 10.1371/Journal.Pone.0124397  0.84
2015 Han C, Yang Y, de Greef BT, Hoeijmakers JG, Gerrits MM, Verhamme C, Qu J, Lauria G, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG. The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy. Neuromolecular Medicine. 17: 158-69. PMID 25791876 DOI: 10.1007/s12017-015-8347-9  1
2015 Han C, Estacion M, Huang J, Vasylyev D, Zhao P, Dib-Hajj SD, Waxman SG. Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons. Journal of Neurophysiology. 113: 3172-85. PMID 25787950 DOI: 10.1152/Jn.00113.2015  1
2015 Shields SD, Butt RP, Dib-Hajj SD, Waxman SG. Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosis. Plos One. 10: e0119067. PMID 25747279 DOI: 10.1371/Journal.Pone.0119067  1
2015 Blanchard MG, Willemsen MH, Walker JB, Dib-Hajj SD, Waxman SG, Jongmans MC, Kleefstra T, van de Warrenburg BP, Praamstra P, Nicolai J, Yntema HG, Bindels RJ, Meisler MH, Kamsteeg EJ. De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy. Journal of Medical Genetics. 52: 330-7. PMID 25725044 DOI: 10.1136/Jmedgenet-2014-102813  0.84
2015 Doppler K, Appeltshauser L, Wilhelmi K, Villmann C, Dib-Hajj SD, Waxman SG, Mäurer M, Weishaupt A, Sommer C. Destruction of paranodal architecture in inflammatory neuropathy with anti-contactin-1 autoantibodies. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 720-8. PMID 25694474 DOI: 10.1136/Jnnp-2014-309916  1
2015 Hoeijmakers JG, Faber CG, Merkies IS, Waxman SG. Painful peripheral neuropathy and sodium channel mutations. Neuroscience Letters. 596: 51-9. PMID 25556685 DOI: 10.1016/j.neulet.2014.12.056  1
2015 Bandaru SP, Liu S, Waxman SG, Tan AM. Dendritic spine dysgenesis contributes to hyperreflexia after spinal cord injury. Journal of Neurophysiology. 113: 1598-615. PMID 25505110 DOI: 10.1152/jn.00566.2014  0.84
2015 Tan AM, Waxman SG. Dendritic spine dysgenesis in neuropathic pain. Neuroscience Letters. 601: 54-60. PMID 25445354 DOI: 10.1016/j.neulet.2014.11.024  0.84
2015 Rice FL, Albrecht PJ, Wymer JP, Black JA, Merkies ISJ, Faber CG, Waxman SG. Sodium channel Nav1.7 in vascular myocytes, endothelium, and innervating axons in human skin Molecular Pain. DOI: 10.1186/s12990-015-0024-3  1
2014 Waxman SG, Merkies IS, Gerrits MM, Dib-Hajj SD, Lauria G, Cox JJ, Wood JN, Woods CG, Drenth JP, Faber CG. Sodium channel genes in pain-related disorders: phenotype-genotype associations and recommendations for clinical use. The Lancet. Neurology. 13: 1152-60. PMID 25316021 DOI: 10.1016/S1474-4422(14)70150-4  1
2014 Brouwer BA, Merkies IS, Gerrits MM, Waxman SG, Hoeijmakers JG, Faber CG. Painful neuropathies: the emerging role of sodium channelopathies. Journal of the Peripheral Nervous System : Jpns. 19: 53-65. PMID 25250524 DOI: 10.1111/jns5.12071  1
2014 de Kovel CG, Meisler MH, Brilstra EH, van Berkestijn FM, van 't Slot R, van Lieshout S, Nijman IJ, O'Brien JE, Hammer MF, Estacion M, Waxman SG, Dib-Hajj SD, Koeleman BP. Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy. Epilepsy Research. 108: 1511-8. PMID 25239001 DOI: 10.1016/J.Eplepsyres.2014.08.020  1
2014 Huang J, Yang Y, Dib-Hajj SD, van Es M, Zhao P, Salomon J, Drenth JP, Waxman SG. Depolarized inactivation overcomes impaired activation to produce DRG neuron hyperexcitability in a Nav1.7 mutation in a patient with distal limb pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12328-40. PMID 25209274 DOI: 10.1523/Jneurosci.2773-14.2014  1
2014 Pappalardo LW, Liu S, Black JA, Waxman SG. Dynamics of sodium channel Nav1.5 expression in astrocytes in mouse models of multiple sclerosis. Neuroreport. 25: 1208-15. PMID 25144393 DOI: 10.1097/WNR.0000000000000249  1
2014 Lauria G, Ziegler D, Malik R, Merkies IS, Waxman SG, Faber CG. The role of sodium channels in painful diabetic and idiopathic neuropathy. Current Diabetes Reports. 14: 538. PMID 25142720 DOI: 10.1007/s11892-014-0538-5  0.4
2014 Dib-Hajj SD, Waxman SG. Translational pain research: Lessons from genetics and genomics. Science Translational Medicine. 6: 249sr4. PMID 25122641 DOI: 10.1126/scitranslmed.3007017  1
2014 Harrer JU, Uçeyler N, Doppler K, Fischer TZ, Dib-Hajj SD, Waxman SG, Sommer C. Neuropathic pain in two-generation twins carrying the sodium channel Nav1.7 functional variant R1150W. Pain. 155: 2199-203. PMID 25116815 DOI: 10.1016/j.pain.2014.08.003  1
2014 Persson AK, Estacion M, Ahn H, Liu S, Stamboulian-Platel S, Waxman SG, Black JA. Contribution of sodium channels to lamellipodial protrusion and Rac1 and ERK1/2 activation in ATP-stimulated microglia. Glia. 62: 2080-95. PMID 25043721 DOI: 10.1002/glia.22728  1
2014 Hoeijmakers JG, Faber CG, Merkies IS, Waxman SG. Channelopathies, painful neuropathy, and diabetes: which way does the causal arrow point? Trends in Molecular Medicine. 20: 544-50. PMID 25008557 DOI: 10.1016/j.molmed.2014.06.003  1
2014 Estacion M, O'Brien JE, Conravey A, Hammer MF, Waxman SG, Dib-Hajj SD, Meisler MH. A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy. Neurobiology of Disease. 69: 117-23. PMID 24874546 DOI: 10.1016/J.Nbd.2014.05.017  1
2014 Devigili G, Eleopra R, Pierro T, Lombardi R, Rinaldo S, Lettieri C, Faber CG, Merkies IS, Waxman SG, Lauria G. Paroxysmal itch caused by gain-of-function Nav1.7 mutation. Pain. 155: 1702-7. PMID 24820863 DOI: 10.1016/j.pain.2014.05.006  1
2014 Huang J, Han C, Estacion M, Vasylyev D, Hoeijmakers JG, Gerrits MM, Tyrrell L, Lauria G, Faber CG, Dib-Hajj SD, Merkies IS, Waxman SG. Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy. Brain : a Journal of Neurology. 137: 1627-42. PMID 24776970 DOI: 10.1093/Brain/Awu079  1
2014 Mishra AM, Bai X, Sanganahalli BG, Waxman SG, Shatillo O, Grohn O, Hyder F, Pitkänen A, Blumenfeld H. Decreased resting functional connectivity after traumatic brain injury in the rat. Plos One. 9: e95280. PMID 24748279 DOI: 10.1371/Journal.Pone.0095280  1
2014 Pappalardo LW, Samad OA, Black JA, Waxman SG. Voltage-gated sodium channel Nav 1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na+ /Ca2+ exchange. Glia. 62: 1162-75. PMID 24740847 DOI: 10.1002/glia.22671  1
2014 Lampert A, Eberhardt M, Waxman SG. Altered sodium channel gating as molecular basis for pain: contribution of activation, inactivation, and resurgent currents. Handbook of Experimental Pharmacology. 221: 91-110. PMID 24737233 DOI: 10.1007/978-3-642-41588-3_5  1
2014 Liu S, Zwinger P, Black JA, Waxman SG. Tapered withdrawal of phenytoin removes protective effect in EAE without inflammatory rebound and mortality. Journal of the Neurological Sciences. 341: 8-12. PMID 24690348 DOI: 10.1016/j.jns.2014.03.029  1
2014 Oliva MK, McGarr TC, Beyer BJ, Gazina E, Kaplan DI, Cordeiro L, Thomas E, Dib-Hajj SD, Waxman SG, Frankel WN, Petrou S. Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy. Neurobiology of Disease. 67: 180-90. PMID 24657915 DOI: 10.1016/j.nbd.2014.03.007  1
2014 Waxman SG, Zamponi GW. Regulating excitability of peripheral afferents: emerging ion channel targets. Nature Neuroscience. 17: 153-63. PMID 24473263 DOI: 10.1038/Nn.3602  1
2014 Black JA, Vasylyev D, Dib-Hajj SD, Waxman SG. Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus. Experimental Neurology. 253: 174-9. PMID 24424281 DOI: 10.1016/j.expneurol.2014.01.004  1
2014 Vasylyev DV, Han C, Zhao P, Dib-Hajj S, Waxman SG. Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H. Journal of Neurophysiology. 111: 1429-43. PMID 24401712 DOI: 10.1152/jn.00763.2013  1
2014 Han C, Vasylyev D, Macala LJ, Gerrits MM, Hoeijmakers JG, Bekelaar KJ, Dib-Hajj SD, Faber CG, Merkies IS, Waxman SG. The G1662S NaV1.8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 499-505. PMID 24006052 DOI: 10.1136/jnnp-2013-306095  1
2014 Mishra AM, Bai X, Sanganahalli BG, Waxman SG, Shatillo O. Decreased resting functional connectivity after traumatic brain injury in the rat (PLoS ONE (2014) 9, 4 (e95280) DOI: 10.1371/journal.pone.0095280) Plos One. 9. DOI: 10.1371/journal.pone.0105899  1
2014 Lauria G, Merkies ISJ, Waxman SG, Faber CG. Approach to small fiber neuropathy Neuromuscular Disorders in Clinical Practice. 2147483647: 507-517. DOI: 10.1007/978-1-4614-6567-6_25  1
2013 Samad OA, Tan AM, Cheng X, Foster E, Dib-Hajj SD, Waxman SG. Virus-mediated shRNA Knockdown of Nav1.3 in Rat Dorsal Root Ganglion Attenuates Nerve Injury-induced Neuropathic Pain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 49-56. PMID 28178604 DOI: 10.1038/mt.2012.169  0.84
2013 Park J, Werley CA, Venkatachalam V, Kralj JM, Dib-Hajj SD, Waxman SG, Cohen AE. Screening fluorescent voltage indicators with spontaneously spiking HEK cells. Plos One. 8: e85221. PMID 24391999 DOI: 10.1371/Journal.Pone.0085221  0.84
2013 Persson AK, Kim I, Zhao P, Estacion M, Black JA, Waxman SG. Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19250-61. PMID 24305821 DOI: 10.1523/JNEUROSCI.2148-13.2013  1
2013 Ommaya AK, Adams KM, Allman RM, Collins EG, Cooper RA, Dixon CE, Fishman PS, Henry JA, Kardon R, Kerns RD, Kupersmith J, Lo A, Macko R, McArdle R, McGlinchey RE, ... ... Waxman SG, et al. Guest editorial: Opportunities in rehabilitation research. Journal of Rehabilitation Research and Development. 50: vii-xxxii. PMID 24203548 DOI: 10.1682/Jrrd.2012.09.0167  1
2013 Bird EV, Christmas CR, Loescher AR, Smith KG, Robinson PP, Black JA, Waxman SG, Boissonade FM. Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas. Molecular Pain. 9: 52. PMID 24144460 DOI: 10.1186/1744-8069-9-52  1
2013 Black JA, Waxman SG. Noncanonical roles of voltage-gated sodium channels. Neuron. 80: 280-91. PMID 24139034 DOI: 10.1016/j.neuron.2013.09.012  1
2013 Yang Y, Vasylyev DV, Dib-Hajj F, Veeramah KR, Hammer MF, Dib-Hajj SD, Waxman SG. Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10.2-R327H demonstrate the role of this residue in stabilizing the channel closed state. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16586-93. PMID 24133262 DOI: 10.1523/JNEUROSCI.2307-13.2013  1
2013 Huang J, Yang Y, Zhao P, Gerrits MM, Hoeijmakers JG, Bekelaar K, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG. Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14087-97. PMID 23986244 DOI: 10.1523/Jneurosci.2710-13.2013  1
2013 Tan AM, Samad OA, Liu S, Bandaru S, Zhao P, Waxman SG. Burn injury-induced mechanical allodynia is maintained by Rac1-regulated dendritic spine dysgenesis. Experimental Neurology. 248: 509-19. PMID 23933578 DOI: 10.1016/j.expneurol.2013.07.017  1
2013 Black JA, Hoeijmakers JG, Faber CG, Merkies IS, Waxman SG. NaV1.7: stress-induced changes in immunoreactivity within magnocellular neurosecretory neurons of the supraoptic nucleus. Molecular Pain. 9: 39. PMID 23924059 DOI: 10.1186/1744-8069-9-39  1
2013 Andres C, Hasenauer J, Ahn HS, Joseph EK, Isensee J, Theis FJ, Allgöwer F, Levine JD, Dib-Hajj SD, Waxman SG, Hucho T. Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia. Pain. 154: 2216-26. PMID 23867734 DOI: 10.1016/j.pain.2013.07.005  1
2013 Ahn HS, Vasylyev DV, Estacion M, Macala LJ, Shah P, Faber CG, Merkies IS, Dib-Hajj SD, Waxman SG. Differential effect of D623N variant and wild-type Na(v)1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons. Brain Research. 1529: 165-77. PMID 23850641 DOI: 10.1016/j.brainres.2013.07.005  1
2013 Waxman SG. Painful Na-channelopathies: an expanding universe. Trends in Molecular Medicine. 19: 406-9. PMID 23664154 DOI: 10.1016/j.molmed.2013.04.003  1
2013 Yang Y, Estacion M, Dib-Hajj SD, Waxman SG. Molecular architecture of a sodium channel S6 helix: radial tuning of the voltage-gated sodium channel 1.7 activation gate. The Journal of Biological Chemistry. 288: 13741-7. PMID 23536180 DOI: 10.1074/jbc.M113.462366  1
2013 Estacion M, Yang Y, Dib-Hajj SD, Tyrrell L, Lin Z, Yang Y, Waxman SG. A new Nav1.7 mutation in an erythromelalgia patient. Biochemical and Biophysical Research Communications. 432: 99-104. PMID 23376079 DOI: 10.1016/j.bbrc.2013.01.079  1
2013 Persson AK, Liu S, Faber CG, Merkies IS, Black JA, Waxman SG. Neuropathy-associated Nav1.7 variant I228M impairs integrity of dorsal root ganglion neuron axons. Annals of Neurology. 73: 140-5. PMID 23280954 DOI: 10.1002/ana.23725  1
2013 Dib-Hajj SD, Yang Y, Black JA, Waxman SG. The Na(V)1.7 sodium channel: from molecule to man. Nature Reviews. Neuroscience. 14: 49-62. PMID 23232607 DOI: 10.1038/nrn3404  1
2013 Estacion M, Waxman SG. The response of Na(V)1.3 sodium channels to ramp stimuli: multiple components and mechanisms. Journal of Neurophysiology. 109: 306-14. PMID 23114218 DOI: 10.1152/jn.00438.2012  1
2013 Black JA, Newcombe J, Waxman SG. Nav1.5 sodium channels in macrophages in multiple sclerosis lesions. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 532-42. PMID 22951351 DOI: 10.1177/1352458512460417  1
2013 Samad OA, Tan AM, Cheng X, Foster E, Dib-Hajj SD, Waxman SG. Virus-mediated shRNA knockdown of Na(v)1.3 in rat dorsal root ganglion attenuates nerve injury-induced neuropathic pain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 49-56. PMID 22910296 DOI: 10.1038/mt.2012.169  1
2013 Waxman SG, Bangalore L. Myelin Function and Saltatory Conduction Neuroglia. DOI: 10.1093/acprof:oso/9780195152227.003.0021  1
2012 Lauria G, Faber CG, Merkies IS, Waxman SG. Diagnosis of neuropathic pain: challenges and possibilities. Expert Opinion On Medical Diagnostics. 6: 89-93. PMID 23480652 DOI: 10.1517/17530059.2012.661712  1
2012 Yang Y, Dib-Hajj SD, Zhang J, Zhang Y, Tyrrell L, Estacion M, Waxman SG. Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel. Nature Communications. 3: 1186. PMID 23149731 DOI: 10.1038/Ncomms2184  1
2012 Black JA, Frézel N, Dib-Hajj SD, Waxman SG. Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn. Molecular Pain. 8: 82. PMID 23134641 DOI: 10.1186/1744-8069-8-82  1
2012 Faber CG, Lauria G, Merkies IS, Cheng X, Han C, Ahn HS, Persson AK, Hoeijmakers JG, Gerrits MM, Pierro T, Lombardi R, Kapetis D, Dib-Hajj SD, Waxman SG. Gain-of-function Nav1.8 mutations in painful neuropathy. Proceedings of the National Academy of Sciences of the United States of America. 109: 19444-9. PMID 23115331 DOI: 10.1073/pnas.1216080109  1
2012 Shields SD, Cheng X, Uçeyler N, Sommer C, Dib-Hajj SD, Waxman SG. Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10819-32. PMID 22875917 DOI: 10.1523/Jneurosci.0304-12.2012  1
2012 Han C, Hoeijmakers JG, Liu S, Gerrits MM, te Morsche RH, Lauria G, Dib-Hajj SD, Drenth JP, Faber CG, Merkies IS, Waxman SG. Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy. Brain : a Journal of Neurology. 135: 2613-28. PMID 22826602 DOI: 10.1093/brain/aws187  1
2012 Vandenberg JI, Waxman SG. Hodgkin and Huxley and the basis for electrical signalling: a remarkable legacy still going strong. The Journal of Physiology. 590: 2569-70. PMID 22787169 DOI: 10.1113/jphysiol.2012.233411  1
2012 Fischer TZ, Waxman SG. Extraterritorial temperature pain threshold abnormalities in subjects with healed thermal injury. Journal of Rehabilitation Research and Development. 49: 515-22. PMID 22773255 DOI: 10.1682/JRRD.2011.04.0071  1
2012 Shields SD, Ahn HS, Yang Y, Han C, Seal RP, Wood JN, Waxman SG, Dib-Hajj SD. Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain. 153: 2017-30. PMID 22703890 DOI: 10.1016/J.Pain.2012.04.022  1
2012 Hoeijmakers JG, Faber CG, Lauria G, Merkies IS, Waxman SG. Small-fibre neuropathies--advances in diagnosis, pathophysiology and management. Nature Reviews. Neurology. 8: 369-79. PMID 22641108 DOI: 10.1038/nrneurol.2012.97  1
2012 Gasser A, Ho TS, Cheng X, Chang KJ, Waxman SG, Rasband MN, Dib-Hajj SD. An ankyrinG-binding motif is necessary and sufficient for targeting Nav1.6 sodium channels to axon initial segments and nodes of Ranvier. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7232-43. PMID 22623668 DOI: 10.1523/Jneurosci.5434-11.2012  1
2012 Tan AM, Samad OA, Fischer TZ, Zhao P, Persson AK, Waxman SG. Maladaptive dendritic spine remodeling contributes to diabetic neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6795-807. PMID 22593049 DOI: 10.1523/JNEUROSCI.1017-12.2012  1
2012 Vasylyev DV, Waxman SG. Membrane properties and electrogenesis in the distal axons of small dorsal root ganglion neurons in vitro. Journal of Neurophysiology. 108: 729-40. PMID 22572942 DOI: 10.1152/jn.00091.2012  1
2012 Hughes JP, Chessell I, Malamut R, Perkins M, Bačkonja M, Baron R, Farrar JT, Field MJ, Gereau RW, Gilron I, McMahon SB, Porreca F, Rappaport BA, Rice F, Richman LK, ... ... Waxman SG, et al. Understanding chronic inflammatory and neuropathic pain. Annals of the New York Academy of Sciences. 1255: 30-44. PMID 22564068 DOI: 10.1111/J.1749-6632.2012.06561.X  1
2012 Han C, Hoeijmakers JG, Ahn HS, Zhao P, Shah P, Lauria G, Gerrits MM, te Morsche RH, Dib-Hajj SD, Drenth JP, Faber CG, Merkies IS, Waxman SG. Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability. Neurology. 78: 1635-43. PMID 22539570 DOI: 10.1212/WNL.0b013e3182574f12  1
2012 O'Brien JE, Sharkey LM, Vallianatos CN, Han C, Blossom JC, Yu T, Waxman SG, Dib-Hajj SD, Meisler MH. Interaction of voltage-gated sodium channel Nav1.6 (SCN8A) with microtubule-associated protein Map1b. The Journal of Biological Chemistry. 287: 18459-66. PMID 22474336 DOI: 10.1074/jbc.M111.336024  1
2012 Baker MD, Waxman SG. Sodium channel slow inactivation and adaptation in C-fibres. The Journal of Physiology. 590: 1513-4. PMID 22467918 DOI: 10.1113/jphysiol.2011.224436  1
2012 Honmou O, Onodera R, Sasaki M, Waxman SG, Kocsis JD. Mesenchymal stem cells: therapeutic outlook for stroke. Trends in Molecular Medicine. 18: 292-7. PMID 22459358 DOI: 10.1016/j.molmed.2012.02.003  1
2012 Wu DF, Chandra D, McMahon T, Wang D, Dadgar J, Kharazia VN, Liang YJ, Waxman SG, Dib-Hajj SD, Messing RO. PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice. The Journal of Clinical Investigation. 122: 1306-15. PMID 22426212 DOI: 10.1172/JCI61934  1
2012 Waxman SG. Sodium channels, the electrogenisome and the electrogenistat: lessons and questions from the clinic. The Journal of Physiology. 590: 2601-12. PMID 22411010 DOI: 10.1113/jphysiol.2012.228460  1
2012 Shields SD, Cheng X, Gasser A, Saab CY, Tyrrell L, Eastman EM, Iwata M, Zwinger PJ, Black JA, Dib-Hajj SD, Waxman SG. A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis. Annals of Neurology. 71: 186-94. PMID 22367990 DOI: 10.1002/Ana.22665  1
2012 Veeramah KR, O'Brien JE, Meisler MH, Cheng X, Dib-Hajj SD, Waxman SG, Talwar D, Girirajan S, Eichler EE, Restifo LL, Erickson RP, Hammer MF. De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP. American Journal of Human Genetics. 90: 502-10. PMID 22365152 DOI: 10.1016/J.Ajhg.2012.01.006  1
2012 Bryce TN, Biering-Sørensen F, Finnerup NB, Cardenas DD, Defrin R, Ivan E, Lundeberg T, Norrbrink C, Richards JS, Siddall P, Stripling T, Treede RD, Waxman SG, Widerström-Noga E, Yezierski RP, et al. International Spinal Cord Injury Pain (ISCIP) Classification: Part 2. Initial validation using vignettes. Spinal Cord. 50: 404-12. PMID 22310319 DOI: 10.1038/sc.2012.2  1
2012 Hoeijmakers JG, Han C, Merkies IS, Macala LJ, Lauria G, Gerrits MM, Dib-Hajj SD, Faber CG, Waxman SG. Small nerve fibres, small hands and small feet: a new syndrome of pain, dysautonomia and acromesomelia in a kindred with a novel NaV1.7 mutation. Brain : a Journal of Neurology. 135: 345-58. PMID 22286749 DOI: 10.1093/brain/awr349  1
2012 Bryce TN, Biering-Sørensen F, Finnerup NB, Cardenas DD, Defrin R, Lundeberg T, Norrbrink C, Richards JS, Siddall P, Stripling T, Treede RD, Waxman SG, Widerström-Noga E, Yezierski RP, Dijkers M. International spinal cord injury pain classification: part I. Background and description. March 6-7, 2009. Spinal Cord. 50: 413-7. PMID 22182852 DOI: 10.1038/sc.2011.156  1
2012 Black JA, Waxman SG. Sodium channels and microglial function. Experimental Neurology. 234: 302-15. PMID 21985863 DOI: 10.1016/j.expneurol.2011.09.030  1
2012 Tan AM, Waxman SG. Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms. Experimental Neurology. 235: 142-51. PMID 21925174 DOI: 10.1016/j.expneurol.2011.08.026  1
2012 Faber CG, Hoeijmakers JG, Ahn HS, Cheng X, Han C, Choi JS, Estacion M, Lauria G, Vanhoutte EK, Gerrits MM, Dib-Hajj S, Drenth JP, Waxman SG, Merkies IS. Gain of function Naν1.7 mutations in idiopathic small fiber neuropathy. Annals of Neurology. 71: 26-39. PMID 21698661 DOI: 10.1002/ana.22485  1
2011 Estacion M, Han C, Choi JS, Hoeijmakers JG, Lauria G, Drenth JP, Gerrits MM, Dib-Hajj SD, Faber CG, Merkies IS, Waxman SG. Intra- and interfamily phenotypic diversity in pain syndromes associated with a gain-of-function variant of NaV1.7. Molecular Pain. 7: 92. PMID 22136189 DOI: 10.1186/1744-8069-7-92  1
2011 Shields SD, Waxman SG. Cerebellar dysfunction in multiple sclerosis: in the blink of an eye. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 1152-4. PMID 21980147 DOI: 10.1177/1352458511410345  1
2011 Tan AM, Chang YW, Zhao P, Hains BC, Waxman SG. Rac1-regulated dendritic spine remodeling contributes to neuropathic pain after peripheral nerve injury. Experimental Neurology. 232: 222-33. PMID 21963650 DOI: 10.1016/j.expneurol.2011.08.028  1
2011 Choi JS, Waxman SG. Physiological interactions between Na(v)1.7 and Na(v)1.8 sodium channels: a computer simulation study. Journal of Neurophysiology. 106: 3173-84. PMID 21940606 DOI: 10.1152/jn.00100.2011  1
2011 Cheng X, Dib-Hajj SD, Tyrrell L, Te Morsche RH, Drenth JP, Waxman SG. Deletion mutation of sodium channel Na(V)1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability. Brain : a Journal of Neurology. 134: 1972-86. PMID 21705421 DOI: 10.1093/brain/awr143  1
2011 Persson AK, Gasser A, Black JA, Waxman SG. Nav1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas. Experimental Neurology. 230: 273-9. PMID 21601570 DOI: 10.1016/j.expneurol.2011.05.005  1
2011 Ahn HS, Black JA, Zhao P, Tyrrell L, Waxman SG, Dib-Hajj SD. Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons. Molecular Pain. 7: 32. PMID 21569247 DOI: 10.1186/1744-8069-7-32  1
2011 Freilich ER, Jones JM, Gaillard WD, Conry JA, Tsuchida TN, Reyes C, Dib-Hajj S, Waxman SG, Meisler MH, Pearl PL. Novel SCN1A mutation in a proband with malignant migrating partial seizures of infancy. Archives of Neurology. 68: 665-71. PMID 21555645 DOI: 10.1001/Archneurol.2011.98  1
2011 Honmou O, Houkin K, Matsunaga T, Niitsu Y, Ishiai S, Onodera R, Waxman SG, Kocsis JD. Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke. Brain : a Journal of Neurology. 134: 1790-807. PMID 21493695 DOI: 10.1093/brain/awr063  1
2011 Waxman SG. Neuroscience: Channelopathies have many faces. Nature. 472: 173-4. PMID 21490662 DOI: 10.1038/472173a  1
2011 Gurkiewicz M, Korngreen A, Waxman SG, Lampert A. Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation. Journal of Neurophysiology. 105: 1546-57. PMID 21289137 DOI: 10.1152/Jn.00703.2010  1
2011 Choi JS, Boralevi F, Brissaud O, Sánchez-Martín J, Te Morsche RH, Dib-Hajj SD, Drenth JP, Waxman SG. Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons. Nature Reviews. Neurology. 7: 51-5. PMID 21079636 DOI: 10.1038/nrneurol.2010.162  1
2010 Persson AK, Black JA, Gasser A, Cheng X, Fischer TZ, Waxman SG. Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals. Molecular Pain. 6: 84. PMID 21118538 DOI: 10.1186/1744-8069-6-84  1
2010 Wilkins A, Kondo Y, Song J, Liu S, Compston A, Black JA, Waxman SG, Duncan ID. Slowly progressive axonal degeneration in a rat model of chronic, nonimmune-mediated demyelination. Journal of Neuropathology and Experimental Neurology. 69: 1256-69. PMID 21107138 DOI: 10.1097/Nen.0B013E3181Ffc317  1
2010 Nikolajsen L, Black JA, Kroner K, Jensen TS, Waxman SG. Neuroma removal for neuropathic pain: efficacy and predictive value of lidocaine infusion. The Clinical Journal of Pain. 26: 788-93. PMID 20973154 DOI: 10.1097/AJP.0b013e3181ed0823  1
2010 Dib-Hajj SD, Waxman SG. Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties. Neuroscience Letters. 486: 84-91. PMID 20817075 DOI: 10.1016/j.neulet.2010.08.077  1
2010 Waxman SG. Polymorphisms in ion channel genes: emerging roles in pain. Brain : a Journal of Neurology. 133: 2515-8. PMID 20802201 DOI: 10.1093/brain/awq240  1
2010 Fischer TZ, Waxman SG. Neuropathic pain in diabetes--evidence for a central mechanism. Nature Reviews. Neurology. 6: 462-6. PMID 20625378 DOI: 10.1038/nrneurol.2010.90  1
2010 Waxman SG. Channelopathic pain: a growing but still small list of model disorders. Neuron. 66: 622-4. PMID 20547120 DOI: 10.1016/j.neuron.2010.05.029  1
2010 Gasser A, Cheng X, Gilmore ES, Tyrrell L, Waxman SG, Dib-Hajj SD. Two Nedd4-binding motifs underlie modulation of sodium channel Nav1.6 by p38 MAPK. The Journal of Biological Chemistry. 285: 26149-61. PMID 20530479 DOI: 10.1074/jbc.M109.098681  1
2010 Estacion M, Waxman SG, Dib-Hajj SD. Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability. Molecular Pain. 6: 35. PMID 20529343 DOI: 10.1186/1744-8069-6-35  1
2010 Choi JS, Cheng X, Foster E, Leffler A, Tyrrell L, Te Morsche RH, Eastman EM, Jansen HJ, Huehne K, Nau C, Dib-Hajj SD, Drenth JP, Waxman SG. Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia. Brain : a Journal of Neurology. 133: 1823-35. PMID 20478850 DOI: 10.1093/brain/awq114  1
2010 Cheng X, Dib-Hajj SD, Tyrrell L, Wright DA, Fischer TZ, Waxman SG. Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders. Molecular Pain. 6: 24. PMID 20429905 DOI: 10.1186/1744-8069-6-24  1
2010 Estacion M, Gasser A, Dib-Hajj SD, Waxman SG. A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons. Experimental Neurology. 224: 362-8. PMID 20420834 DOI: 10.1016/j.expneurol.2010.04.012  1
2010 Chang YW, Waxman SG. Minocycline attenuates mechanical allodynia and central sensitization following peripheral second-degree burn injury. The Journal of Pain : Official Journal of the American Pain Society. 11: 1146-54. PMID 20418178 DOI: 10.1016/j.jpain.2010.02.010  1
2010 Ahn HS, Dib-Hajj SD, Cox JJ, Tyrrell L, Elmslie FV, Clarke AA, Drenth JP, Woods CG, Waxman SG. A new Nav1.7 sodium channel mutation I234T in a child with severe pain. European Journal of Pain (London, England). 14: 944-50. PMID 20385509 DOI: 10.1016/j.ejpain.2010.03.007  1
2010 Kullmann DM, Waxman SG. Neurological channelopathies: new insights into disease mechanisms and ion channel function. The Journal of Physiology. 588: 1823-7. PMID 20375141 DOI: 10.1113/jphysiol.2010.190652  1
2010 Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. Sodium channels in normal and pathological pain. Annual Review of Neuroscience. 33: 325-47. PMID 20367448 DOI: 10.1146/Annurev-Neuro-060909-153234  1
2010 Black JA, Newcombe J, Waxman SG. Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5. Brain : a Journal of Neurology. 133: 835-46. PMID 20147455 DOI: 10.1093/brain/awq003  1
2010 Fischer TZ, Waxman SG. Familial pain syndromes from mutations of the NaV1.7 sodium channel. Annals of the New York Academy of Sciences. 1184: 196-207. PMID 20146699 DOI: 10.1111/j.1749-6632.2009.05110.x  1
2010 Stamboulian S, Choi JS, Ahn HS, Chang YW, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD. ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1637-47. PMID 20130174 DOI: 10.1523/JNEUROSCI.4872-09.2010  1
2010 Estacion M, Choi JS, Eastman EM, Lin Z, Li Y, Tyrrell L, Yang Y, Dib-Hajj SD, Waxman SG. Can robots patch-clamp as well as humans? Characterization of a novel sodium channel mutation. The Journal of Physiology. 588: 1915-27. PMID 20123784 DOI: 10.1113/jphysiol.2009.186114  1
2010 Chang YW, Tan A, Saab C, Waxman S. Unilateral focal burn injury is followed by long-lasting bilateral allodynia and neuronal hyperexcitability in spinal cord dorsal horn. The Journal of Pain : Official Journal of the American Pain Society. 11: 119-30. PMID 19744891 DOI: 10.1016/J.Jpain.2009.06.009  1
2010 Bangalore L, Black JA, Carrithers MD, Waxman SG. Sodium channel expression and function in multiple sclerosis Multiple Sclerosis: Recovery of Function and Neurorehabilitation. 29-43. DOI: 10.1017/CBO9780511781698.005  1
2010 Rush AM, Waxman SG. Dorsal Root Ganglion Neurons Encyclopedia of Neuroscience. 615-619. DOI: 10.1016/B978-008045046-9.01660-0  1
2009 Estacion M, Harty TP, Choi JS, Tyrrell L, Dib-Hajj SD, Waxman SG. A sodium channel gene SCN9A polymorphism that increases nociceptor excitability. Annals of Neurology. 66: 862-6. PMID 20033988 DOI: 10.1002/ana.21895  1
2009 Waxman SG. An exciting year for neuroscience, and for Neuroscience Letters. Neuroscience Letters. 467: 187. PMID 19818383 DOI: 10.1016/j.neulet.2009.09.059  1
2009 Dib-Hajj SD, Black JA, Waxman SG. Voltage-gated sodium channels: therapeutic targets for pain. Pain Medicine (Malden, Mass.). 10: 1260-9. PMID 19818036 DOI: 10.1111/j.1526-4637.2009.00719.x  1
2009 Lampert A, Dib-Hajj SD, Eastman EM, Tyrrell L, Lin Z, Yang Y, Waxman SG. Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials. Biochemical and Biophysical Research Communications. 390: 319-24. PMID 19800314 DOI: 10.1016/j.bbrc.2009.09.121  1
2009 Tan AM, Choi JS, Waxman SG, Hains BC. Dendritic spine remodeling after spinal cord injury alters neuronal signal processing. Journal of Neurophysiology. 102: 2396-409. PMID 19692517 DOI: 10.1152/jn.00095.2009  1
2009 Dib-Hajj SD, Choi JS, Macala LJ, Tyrrell L, Black JA, Cummins TR, Waxman SG. Transfection of rat or mouse neurons by biolistics or electroporation. Nature Protocols. 4: 1118-26. PMID 19617884 DOI: 10.1038/Nprot.2009.90  1
2009 Cummins TR, Rush AM, Estacion M, Dib-Hajj SD, Waxman SG. Voltage-clamp and current-clamp recordings from mammalian DRG neurons. Nature Protocols. 4: 1103-12. PMID 19617882 DOI: 10.1038/Nprot.2009.91  1
2009 Fischer TZ, Gilmore ES, Estacion M, Eastman E, Taylor S, Melanson M, Dib-Hajj SD, Waxman SG. A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia. Annals of Neurology. 65: 733-41. PMID 19557861 DOI: 10.1002/ana.21678  1
2009 Tan AM, Zhao P, Waxman SG, Hains BC. Early microglial inhibition preemptively mitigates chronic pain development after experimental spinal cord injury. Journal of Rehabilitation Research and Development. 46: 123-33. PMID 19533525  0.84
2009 Laezza F, Lampert A, Kozel MA, Gerber BR, Rush AM, Nerbonne JM, Waxman SG, Dib-Hajj SD, Ornitz DM. FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels. Molecular and Cellular Neurosciences. 42: 90-101. PMID 19465131 DOI: 10.1016/J.Mcn.2009.05.007  1
2009 Han C, Dib-Hajj SD, Lin Z, Li Y, Eastman EM, Tyrrell L, Cao X, Yang Y, Waxman SG. Early- and late-onset inherited erythromelalgia: genotype-phenotype correlation. Brain : a Journal of Neurology. 132: 1711-22. PMID 19369487 DOI: 10.1093/brain/awp078  1
2009 Fischer TZ, Tan AM, Waxman SG. Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain. Brain Research. 1268: 154-61. PMID 19285053 DOI: 10.1016/j.brainres.2009.02.063  1
2009 Sharkey LM, Cheng X, Drews V, Buchner DA, Jones JM, Justice MJ, Waxman SG, Dib-Hajj SD, Meisler MH. The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2733-41. PMID 19261867 DOI: 10.1523/Jneurosci.6026-08.2009  1
2009 Choi JS, Zhang L, Dib-Hajj SD, Han C, Tyrrell L, Lin Z, Wang X, Yang Y, Waxman SG. Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off. Experimental Neurology. 216: 383-9. PMID 19162012 DOI: 10.1016/j.expneurol.2008.12.012  1
2009 Carrithers MD, Chatterjee G, Carrithers LM, Offoha R, Iheagwara U, Rahner C, Graham M, Waxman SG. Regulation of podosome formation in macrophages by a splice variant of the sodium channel SCN8A. The Journal of Biological Chemistry. 284: 8114-26. PMID 19136557 DOI: 10.1074/jbc.M801892200  1
2009 Black JA, Liu S, Waxman SG. Sodium channel activity modulates multiple functions in microglia. Glia. 57: 1072-81. PMID 19115387 DOI: 10.1002/glia.20830  1
2009 Blumenfeld H, Lampert A, Klein JP, Mission J, Chen MC, Rivera M, Dib-Hajj S, Brennan AR, Hains BC, Waxman SG. Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis. Epilepsia. 50: 44-55. PMID 18637833 DOI: 10.1111/J.1528-1167.2008.01710.X  1
2009 Stys PK, Ransom BR, Black JA, Waxman SG. Anoxic/ischemic injury in axons The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0024  1
2009 Waxman SG, Kocsis JD, Black JA. Pathophysiology of demyelinated axons The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0023  1
2009 Stys PK, Waxman SG, Ransom BR. Ion pumps and exchangers The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0015  1
2009 Waxman SG. Voltage-gated ion channels in axons: Localization, function, and development The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0011  1
2009 Black JA, Sontheimer H, Oh Y, Waxman SG. The oligodendrocyte, the perinodal astrocyte, and the central node of Ranvier The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0006  1
2009 Waxman SG, Kocsis JD, Stys PK. The Axon: Structure, Function and Pathophysiology The Axon: Structure, Function and Pathophysiology. 1-708. DOI: 10.1093/acprof:oso/9780195082937.001.0001  1
2008 Dib-Hajj SD, Yang Y, Waxman SG. Genetics and molecular pathophysiology of Na(v)1.7-related pain syndromes. Advances in Genetics. 63: 85-110. PMID 19185186 DOI: 10.1016/S0065-2660(08)01004-3  1
2008 Black JA, Nikolajsen L, Kroner K, Jensen TS, Waxman SG. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas. Annals of Neurology. 64: 644-53. PMID 19107992 DOI: 10.1002/ana.21527  1
2008 Tan AM, Stamboulian S, Chang YW, Zhao P, Hains AB, Waxman SG, Hains BC. Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13173-83. PMID 19052208 DOI: 10.1523/JNEUROSCI.3142-08.2008  1
2008 Estacion M, Dib-Hajj SD, Benke PJ, Te Morsche RH, Eastman EM, Macala LJ, Drenth JP, Waxman SG. NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11079-88. PMID 18945915 DOI: 10.1523/JNEUROSCI.3443-08.2008  1
2008 Dib-Hajj SD, Estacion M, Jarecki BW, Tyrrell L, Fischer TZ, Lawden M, Cummins TR, Waxman SG. Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable. Molecular Pain. 4: 37. PMID 18803825 DOI: 10.1186/1744-8069-4-37  1
2008 Lampert A, O'Reilly AO, Dib-Hajj SD, Tyrrell L, Wallace BA, Waxman SG. A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation. The Journal of Biological Chemistry. 283: 24118-27. PMID 18550534 DOI: 10.1074/jbc.M802900200  1
2008 Saab CY, Waxman SG, Hains BC. Alarm or curse? The pain of neuroinflammation. Brain Research Reviews. 58: 226-35. PMID 18486228 DOI: 10.1016/J.Brainresrev.2008.04.002  1
2008 Black JA, Waxman SG. Phenytoin protects central axons in experimental autoimmune encephalomyelitis. Journal of the Neurological Sciences. 274: 57-63. PMID 18485368 DOI: 10.1016/j.jns.2008.04.001  1
2008 Zhao P, Barr TP, Hou Q, Dib-Hajj SD, Black JA, Albrecht PJ, Petersen K, Eisenberg E, Wymer JP, Rice FL, Waxman SG. Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain. Pain. 139: 90-105. PMID 18442883 DOI: 10.1016/J.Pain.2008.03.016  1
2008 Deumens R, Joosten EA, Waxman SG, Hains BC. Locomotor dysfunction and pain: the scylla and charybdis of fiber sprouting after spinal cord injury. Molecular Neurobiology. 37: 52-63. PMID 18415034 DOI: 10.1007/s12035-008-8016-1  1
2008 Hudmon A, Choi JS, Tyrrell L, Black JA, Rush AM, Waxman SG, Dib-Hajj SD. Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3190-201. PMID 18354022 DOI: 10.1523/Jneurosci.4403-07.2008  1
2008 Waxman SG. Axonal dysfunction in chronic multiple sclerosis: meltdown in the membrane. Annals of Neurology. 63: 411-3. PMID 18350590 DOI: 10.1002/ana.21361  1
2008 Waxman SG, Estacion M. Nav1.9, G-proteins, and nociceptors. The Journal of Physiology. 586: 917-8. PMID 18287383 DOI: 10.1113/jphysiol.2007.149922  1
2008 Waxman SG. Mechanisms of disease: sodium channels and neuroprotection in multiple sclerosis-current status. Nature Clinical Practice. Neurology. 4: 159-69. PMID 18227822 DOI: 10.1038/ncpneuro0735  1
2008 Shaw SK, Owolabi SA, Bagley J, Morin N, Cheng E, LeBlanc BW, Kim M, Harty P, Waxman SG, Saab CY. Activated polymorphonuclear cells promote injury and excitability of dorsal root ganglia neurons. Experimental Neurology. 210: 286-94. PMID 18201702 DOI: 10.1016/J.Expneurol.2007.11.024  1
2008 Cheng X, Dib-Hajj SD, Tyrrell L, Waxman SG. Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade. Molecular Pain. 4: 1. PMID 18171466 DOI: 10.1186/1744-8069-4-1  1
2008 Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, ... ... Waxman SG, et al. Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia. 49: 400-9. PMID 18070091 DOI: 10.1111/J.1528-1167.2007.01458.X  1
2008 Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC. Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response. Molecular Pharmacology. 73: 243-51. PMID 17959714 DOI: 10.1124/Mol.107.039594  1
2008 Dib-Hajj SD, Hains BC, Black JA, Waxman SG. Voltage-Gated Sodium Channels: Multiple Roles in the Pathophysiology of Pain Structure, Function, and Modulation of Neuronal Voltagegated Ion Channels. 67-104. DOI: 10.1002/9780470429907.ch3  1
2007 Drenth JP, Waxman SG. Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders. The Journal of Clinical Investigation. 117: 3603-9. PMID 18060017 DOI: 10.1172/JCI33297  1
2007 Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. From genes to pain: Na v 1.7 and human pain disorders. Trends in Neurosciences. 30: 555-63. PMID 17950472 DOI: 10.1016/J.Tins.2007.08.004  1
2007 Waxman SG, Black JA. Retinal involvement in multiple sclerosis. Neurology. 69: 1562-3. PMID 17938366 DOI: 10.1212/01.wnl.0000295993.08468.f3  1
2007 Black JA, Newcombe J, Trapp BD, Waxman SG. Sodium channel expression within chronic multiple sclerosis plaques. Journal of Neuropathology and Experimental Neurology. 66: 828-37. PMID 17805013 DOI: 10.1097/nen.0b013e3181462841  1
2007 Cummins TR, Sheets PL, Waxman SG. The roles of sodium channels in nociception: Implications for mechanisms of pain. Pain. 131: 243-57. PMID 17766042 DOI: 10.1016/J.Pain.2007.07.026  1
2007 Zhao P, Waxman SG, Hains BC. Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8893-902. PMID 17699671 DOI: 10.1523/JNEUROSCI.2209-07.2007  1
2007 Waxman SG. Nav1.7, its mutations, and the syndromes that they cause. Neurology. 69: 505-7. PMID 17679668 DOI: 10.1212/01.wnl.0000268068.02343.37  1
2007 Black JA, Liu S, Carrithers M, Carrithers LM, Waxman SG. Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine. Annals of Neurology. 62: 21-33. PMID 17654737 DOI: 10.1002/ana.21172  1
2007 Kocsis JD, Waxman SG. Schwann cells and their precursors for repair of central nervous system myelin. Brain : a Journal of Neurology. 130: 1978-80. PMID 17626033 DOI: 10.1093/brain/awm161  1
2007 Hains BC, Waxman SG. Sodium channel expression and the molecular pathophysiology of pain after SCI. Progress in Brain Research. 161: 195-203. PMID 17618978 DOI: 10.1016/S0079-6123(06)61013-3  1
2007 Carrithers MD, Dib-Hajj S, Carrithers LM, Tokmoulina G, Pypaert M, Jonas EA, Waxman SG. Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification. Journal of Immunology (Baltimore, Md. : 1950). 178: 7822-32. PMID 17548620 DOI: 10.4049/Jimmunol.178.12.7822  1
2007 Patrick Harty T, Waxman SG. Inactivation properties of sodium channel Nav1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization. Molecular Pain. 3: 12. PMID 17540018 DOI: 10.1186/1744-8069-3-12  1
2007 Sheets PL, Jackson JO, Waxman SG, Dib-Hajj SD, Cummins TR. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity. The Journal of Physiology. 581: 1019-31. PMID 17430993 DOI: 10.1113/Jphysiol.2006.127027  1
2007 Novella SP, Hisama FM, Dib-Hajj SD, Waxman SG. A case of inherited erythromelalgia. Nature Clinical Practice. Neurology. 3: 229-34. PMID 17410110 DOI: 10.1038/ncpneuro0425  1
2007 Waxman SG. Channel, neuronal and clinical function in sodium channelopathies: from genotype to phenotype. Nature Neuroscience. 10: 405-9. PMID 17387329 DOI: 10.1038/nn1857  1
2007 Woolfe F, Waxman SG, Hains BC. In silico modeling of axonal reconnection within a discrete fiber tract after spinal cord injury. Journal of Neurotrauma. 24: 421-32. PMID 17376004 DOI: 10.1089/neu.2006.0131  1
2007 Zhao P, Waxman SG, Hains BC. Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2357-68. PMID 17329433 DOI: 10.1523/JNEUROSCI.0138-07.2007  1
2007 Han C, Lampert A, Rush AM, Dib-Hajj SD, Wang X, Yang Y, Waxman SG. Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7. Molecular Pain. 3: 3. PMID 17239250 DOI: 10.1186/1744-8069-3-3  1
2007 Rush AM, Cummins TR, Waxman SG. Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons. The Journal of Physiology. 579: 1-14. PMID 17158175 DOI: 10.1113/Jphysiol.2006.121483  1
2007 Choi JS, Dib-Hajj SD, Waxman SG. Differential slow inactivation and use-dependent inhibition of Nav1.8 channels contribute to distinct firing properties in IB4+ and IB4- DRG neurons. Journal of Neurophysiology. 97: 1258-65. PMID 17108087 DOI: 10.1152/jn.01033.2006  1
2007 Wood JN, Waxman SG. Chronic Pain as a Molecular Disorder Molecular Neurology. 427-438. DOI: 10.1016/B978-012369509-3.50029-9  1
2007 Waxman SG. Multiple Sclerosis as a Neurodegenerative Disease Molecular Neurology. 333-346. DOI: 10.1016/B978-012369509-3.50024-X  1
2007 Harel NY, Yang YS, Strittmatter SM, Kocsis JD, Waxman SG. The Dawn of Molecular and Cellular Therapies for Traumatic Spinal Cord Injury Molecular Neurology. 207-220. DOI: 10.1016/B978-012369509-3.50016-0  1
2007 Waxman SG. Preface Molecular Neurology. xi-xi. DOI: 10.1016/B978-012369509-3.50002-0  1
2007 Waxman SG. Molecular Neurology Molecular Neurology.  1
2006 Waxman SG. Neurobiology: a channel sets the gain on pain. Nature. 444: 831-2. PMID 17167466 DOI: 10.1038/444831a  1
2006 Harty TP, Dib-Hajj SD, Tyrrell L, Blackman R, Hisama FM, Rose JB, Waxman SG. Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12566-75. PMID 17135418 DOI: 10.1523/Jneurosci.3424-06.2006  1
2006 Waxman SG. Axonal conduction and injury in multiple sclerosis: the role of sodium channels. Nature Reviews. Neuroscience. 7: 932-41. PMID 17115075 DOI: 10.1038/nrn2023  1
2006 Lampert A, Dib-Hajj SD, Tyrrell L, Waxman SG. Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating. The Journal of Biological Chemistry. 281: 36029-35. PMID 17008310 DOI: 10.1074/jbc.M607637200  1
2006 Choi JS, Dib-Hajj SD, Waxman SG. Inherited erythermalgia: limb pain from an S4 charge-neutral Na channelopathy. Neurology. 67: 1563-7. PMID 16988069 DOI: 10.1212/01.wnl.0000231514.33603.1e  0.64
2006 Black JA, Liu S, Hains BC, Saab CY, Waxman SG. Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE. Brain : a Journal of Neurology. 129: 3196-208. PMID 16931536 DOI: 10.1093/Brain/Awl216  1
2006 Zhao P, Waxman SG, Hains BC. Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury. Molecular Pain. 2: 27. PMID 16916452 DOI: 10.1186/1744-8069-2-27  1
2006 Fang X, Djouhri L, McMullan S, Berry C, Waxman SG, Okuse K, Lawson SN. Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes C-fiber nociceptors with broad action potentials and high Nav1.9 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7281-92. PMID 16822986 DOI: 10.1523/JNEUROSCI.1072-06.2006  1
2006 Rush AM, Wittmack EK, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily. The European Journal of Neuroscience. 23: 2551-62. PMID 16817858 DOI: 10.1111/J.1460-9568.2006.04789.X  1
2006 Lampert A, Hains BC, Waxman SG. Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury. Experimental Brain Research. 174: 660-6. PMID 16718433 DOI: 10.1007/s00221-006-0511-x  1
2006 Rush AM, Dib-Hajj SD, Liu S, Cummins TR, Black JA, Waxman SG. A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 8245-50. PMID 16702558 DOI: 10.1073/Pnas.0602813103  1
2006 Hains BC, Waxman SG. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4308-17. PMID 16624951 DOI: 10.1523/JNEUROSCI.0003-06.2006  1
2006 Choi JS, Hudmon A, Waxman SG, Dib-Hajj SD. Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. Journal of Neurophysiology. 96: 97-108. PMID 16598065 DOI: 10.1152/jn.00854.2005  1
2006 Black JA, Waxman SG, Smith KJ. Remyelination of dorsal column axons by endogenous Schwann cells restores the normal pattern of Nav1.6 and Kv1.2 at nodes of Ranvier. Brain : a Journal of Neurology. 129: 1319-29. PMID 16537565 DOI: 10.1093/Brain/Awl057  1
2006 Waxman SG, Hains BC. Fire and phantoms after spinal cord injury: Na+ channels and central pain. Trends in Neurosciences. 29: 207-15. PMID 16494954 DOI: 10.1016/j.tins.2006.02.003  1
2006 Hains BC, Saab CY, Waxman SG. Alterations in burst firing of thalamic VPL neurons and reversal by Na(v)1.3 antisense after spinal cord injury. Journal of Neurophysiology. 95: 3343-52. PMID 16481457 DOI: 10.1152/Jn.01009.2005  1
2006 Sasaki M, Black JA, Lankford KL, Tokuno HA, Waxman SG, Kocsis JD. Molecular reconstruction of nodes of Ranvier after remyelination by transplanted olfactory ensheathing cells in the demyelinated spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1803-12. PMID 16467529 DOI: 10.1523/JNEUROSCI.3611-05.2006  1
2006 Han C, Rush AM, Dib-Hajj SD, Li S, Xu Z, Wang Y, Tyrrell L, Wang X, Yang Y, Waxman SG. Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7. Annals of Neurology. 59: 553-8. PMID 16392115 DOI: 10.1002/ana.20776  1
2006 Sasaki M, Hains BC, Lankford KL, Waxman SG, Kocsis JD. Protection of corticospinal tract neurons after dorsal spinal cord transection and engraftment of olfactory ensheathing cells. Glia. 53: 352-9. PMID 16288464 DOI: 10.1002/glia.20285  1
2006 Wang S, Davis BM, Zwick M, Waxman SG, Albers KM. Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged mice. Neurobiology of Aging. 27: 895-903. PMID 15979214 DOI: 10.1016/J.Neurobiolaging.2005.04.009  1
2006 Dib-Hajj SD, Rush AM, Cummins TR, Waxman SG. Mutations in the sodium channel Nav1.7 underlie inherited erythromelalgia Drug Discovery Today: Disease Mechanisms. 3: 343-350. DOI: 10.1016/J.Ddmec.2006.09.005  1
2005 Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacological Reviews. 57: 397-409. PMID 16382098 DOI: 10.1124/pr.57.4.4  1
2005 Waxman SG, Dib-Hajj S. Erythermalgia: molecular basis for an inherited pain syndrome. Trends in Molecular Medicine. 11: 555-62. PMID 16278094 DOI: 10.1016/j.molmed.2005.10.004  0.48
2005 Hains BC, Waxman SG. Neuroprotection by sodium channel blockade with phenytoin in an experimental model of glaucoma. Investigative Ophthalmology & Visual Science. 46: 4164-9. PMID 16249495 DOI: 10.1167/iovs.05-0618  1
2005 Hains BC, Saab CY, Waxman SG. Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury. Brain : a Journal of Neurology. 128: 2359-71. PMID 16109750 DOI: 10.1093/Brain/Awh623  1
2005 Rush AM, Craner MJ, Kageyama T, Dib-Hajj SD, Waxman SG, Ranscht B. Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons. The European Journal of Neuroscience. 22: 39-49. PMID 16029194 DOI: 10.1111/j.1460-9568.2005.04186.x  1
2005 Wittmack EK, Rush AM, Hudmon A, Waxman SG, Dib-Hajj SD. Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6621-30. PMID 16014723 DOI: 10.1523/Jneurosci.0541-05.2005  1
2005 Leffler A, Herzog RI, Dib-Hajj SD, Waxman SG, Cummins TR. Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue. PflüGers Archiv : European Journal of Physiology. 451: 454-63. PMID 15981012 DOI: 10.1007/S00424-005-1463-X  1
2005 Dib-Hajj SD, Rush AM, Cummins TR, Hisama FM, Novella S, Tyrrell L, Marshall L, Waxman SG. Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons. Brain : a Journal of Neurology. 128: 1847-54. PMID 15958509 DOI: 10.1093/Brain/Awh514  1
2005 Waxman SG, Dib-Hajj SD. Erythromelalgia: a hereditary pain syndrome enters the molecular era. Annals of Neurology. 57: 785-8. PMID 15929046 DOI: 10.1002/ana.20511  0.64
2005 Fang X, Djouhri L, McMullan S, Berry C, Okuse K, Waxman SG, Lawson SN. trkA is expressed in nociceptive neurons and influences electrophysiological properties via Nav1.8 expression in rapidly conducting nociceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4868-78. PMID 15888662 DOI: 10.1523/JNEUROSCI.0249-05.2005  1
2005 Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge M, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, ... ... Waxman SG, et al. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord. 43: 453-8. PMID 15824756 DOI: 10.1038/Sj.Sc.3101746  1
2005 Cummins TR, Dib-Hajj SD, Herzog RI, Waxman SG. Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons. Febs Letters. 579: 2166-70. PMID 15811336 DOI: 10.1016/J.Febslet.2005.03.009  1
2005 Liu C, Cummins TR, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD. CAP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Na(v)1.8. Molecular and Cellular Neurosciences. 28: 636-49. PMID 15797711 DOI: 10.1016/J.Mcn.2004.11.007  1
2005 Rush AM, Dib-Hajj SD, Waxman SG. Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones. The Journal of Physiology. 564: 803-15. PMID 15760941 DOI: 10.1113/jphysiol.2005.083089  1
2005 Waxman SG, Geschwind N. Hypergraphia in temporal lobe epilepsy. 1974. Epilepsy & Behavior : E&B. 6: 282-91. PMID 15710320 DOI: 10.1016/j.yebeh.2004.11.022  1
2005 Craner MJ, Damarjian TG, Liu S, Hains BC, Lo AC, Black JA, Newcombe J, Cuzner ML, Waxman SG. Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia. 49: 220-9. PMID 15390090 DOI: 10.1002/glia.20112  1
2005 Cummins TR, Waxman SG. Neuronal Blocking Factors in Demyelinating Diseases Multiple Sclerosis as a Neuronal Disease. 317-326. DOI: 10.1016/B978-012738761-1/50023-7  1
2005 Stys PK, Waxman SG. Molecular Mechanisms of Calcium Influx in Axonal Degeneration Multiple Sclerosis as a Neuronal Disease. 275-292. DOI: 10.1016/B978-012738761-1/50020-1  1
2005 Smith KJ, Waxman SG. The Conduction Properties of Demyelinated and Remyelinated Axons Multiple Sclerosis as a Neuronal Disease. 85-100. DOI: 10.1016/B978-012738761-1/50007-9  1
2004 Waxman SG, Craner MJ, Black JA. Na+ channel expression along axons in multiple sclerosis and its models. Trends in Pharmacological Sciences. 25: 584-91. PMID 15491781 DOI: 10.1016/j.tips.2004.09.001  1
2004 Damarjian TG, Craner MJ, Black JA, Waxman SG. Upregulation and colocalization of p75 and Nav1.8 in Purkinje neurons in experimental autoimmune encephalomyelitis. Neuroscience Letters. 369: 186-90. PMID 15464262 DOI: 10.1016/j.neulet.2004.07.023  0.88
2004 Cummins TR, Dib-Hajj SD, Waxman SG. Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8232-6. PMID 15385606 DOI: 10.1523/Jneurosci.2695-04.2004  1
2004 Rush AM, Waxman SG. PGE2 increases the tetrodotoxin-resistant Nav1.9 sodium current in mouse DRG neurons via G-proteins. Brain Research. 1023: 264-71. PMID 15374752 DOI: 10.1016/j.brainres.2004.07.042  1
2004 Shah BS, Rush AM, Liu S, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7387-99. PMID 15317864 DOI: 10.1523/JNEUROSCI.0322-04.2004  1
2004 Choi JS, Tyrrell L, Waxman SG, Dib-Hajj SD. Functional role of the C-terminus of voltage-gated sodium channel Na(v)1.8. Febs Letters. 572: 256-60. PMID 15304358 DOI: 10.1016/j.febslet.2004.07.047  1
2004 Wittmack EK, Rush AM, Craner MJ, Goldfarb M, Waxman SG, Dib-Hajj SD. Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6765-75. PMID 15282281 DOI: 10.1523/Jneurosci.1628-04.2004  1
2004 Saab CY, Waxman SG. Potentiation of sural nerve Abeta action potential after neurogenic inflammation. Neuroreport. 15: 1773-7. PMID 15257145 DOI: 10.1097/01.Wnr.0000137076.18387.32  1
2004 Hains BC, Saab CY, Lo AC, Waxman SG. Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal conduction, and improves functional motor recovery after contusion SCI. Experimental Neurology. 188: 365-77. PMID 15246836 DOI: 10.1016/J.Expneurol.2004.04.001  1
2004 Hains BC, Saab CY, Klein JP, Craner MJ, Waxman SG. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4832-9. PMID 15152043 DOI: 10.1523/Jneurosci.0300-04.2004  1
2004 Craner MJ, Newcombe J, Black JA, Hartle C, Cuzner ML, Waxman SG. Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger. Proceedings of the National Academy of Sciences of the United States of America. 101: 8168-73. PMID 15148385 DOI: 10.1073/pnas.0402765101  0.88
2004 Saab CY, Craner MJ, Kataoka Y, Waxman SG. Abnormal Purkinje cell activity in vivo in experimental allergic encephalomyelitis. Experimental Brain Research. 158: 1-8. PMID 15118796 DOI: 10.1007/S00221-004-1867-4  1
2004 Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H. Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy. Brain Research. 1000: 102-9. PMID 15053958 DOI: 10.1016/j.brainres.2003.11.051  1
2004 Black JA, Liu S, Tanaka M, Cummins TR, Waxman SG. Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain. 108: 237-47. PMID 15030943 DOI: 10.1016/J.Pain.2003.12.035  1
2004 Klein JP, Hains BC, Craner MJ, Black JA, Waxman SG. Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus. Neurobiology of Disease. 15: 221-8. PMID 15006692 DOI: 10.1016/j.nbd.2003.10.009  1
2004 Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG. Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain : a Journal of Neurology. 127: 294-303. PMID 14662515 DOI: 10.1093/brain/awh032  1
2003 Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XXXIX. Compendium of voltage-gated ion channels: sodium channels. Pharmacological Reviews. 55: 575-8. PMID 14657413 DOI: 10.1124/Pr.55.4.7  1
2003 Craner MJ, Kataoka Y, Lo AC, Black JA, Baker D, Waxman SG. Temporal course of upregulation of Na(v)1.8 in Purkinje neurons parallels the progression of clinical deficit in experimental allergic encephalomyelitis. Journal of Neuropathology and Experimental Neurology. 62: 968-75. PMID 14533785 DOI: 10.1093/Jnen/62.9.968  0.88
2003 Hains BC, Klein JP, Saab CY, Craner MJ, Black JA, Waxman SG. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8881-92. PMID 14523090 DOI: 10.1523/Jneurosci.23-26-08881.2003  1
2003 Klein JP, Tendi EA, Dib-Hajj SD, Fields RD, Waxman SG. Patterned electrical activity modulates sodium channel expression in sensory neurons. Journal of Neuroscience Research. 74: 192-8. PMID 14515348 DOI: 10.1002/jnr.10768  1
2003 Herzog RI, Liu C, Waxman SG, Cummins TR. Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8261-70. PMID 12967988 DOI: 10.1523/Jneurosci.23-23-08261.2003  1
2003 Klein JP, Waxman SG. The brain in diabetes: molecular changes in neurons and their implications for end-organ damage. The Lancet. Neurology. 2: 548-54. PMID 12941577 DOI: 10.1016/S1474-4422(03)00503-9  1
2003 Lo AC, Saab CY, Black JA, Waxman SG. Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo. Journal of Neurophysiology. 90: 3566-71. PMID 12904334 DOI: 10.1152/Jn.00434.2003  1
2003 Saab CY, Cummins TR, Waxman SG. GTP gamma S increases Nav1.8 current in small-diameter dorsal root ganglia neurons. Experimental Brain Research. 152: 415-9. PMID 12898089 DOI: 10.1007/S00221-003-1565-7  1
2003 Tokuno HA, Kocsis JD, Waxman SG. Noninactivating, tetrodotoxin-sensitive Na+ conductance in peripheral axons. Muscle & Nerve. 28: 212-7. PMID 12872326 DOI: 10.1002/mus.10421  1
2003 Herzog RI, Cummins TR, Ghassemi F, Dib-Hajj SD, Waxman SG. Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons. The Journal of Physiology. 551: 741-50. PMID 12843211 DOI: 10.1111/J.1469-7793.2003.00741.X  1
2003 Craner MJ, Lo AC, Black JA, Waxman SG. Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination. Brain : a Journal of Neurology. 126: 1552-61. PMID 12805113 DOI: 10.1093/brain/awg153  0.88
2003 Weisman D, Hisama FM, Waxman SG, Blumenfeld H. Going deep to cut the link: cortical disconnection syndrome caused by a thalamic lesion. Neurology. 60: 1865-6. PMID 12796557 DOI: 10.1212/01.Wnl.0000066051.14414.Ff  1
2003 Hains BC, Black JA, Waxman SG. Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury. The Journal of Comparative Neurology. 462: 328-41. PMID 12794736 DOI: 10.1002/cne.10733  1
2003 Rugiero F, Mistry M, Sage D, Black JA, Waxman SG, Crest M, Clerc N, Delmas P, Gola M. Selective expression of a persistent tetrodotoxin-resistant Na+ current and NaV1.9 subunit in myenteric sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2715-25. PMID 12684457 DOI: 10.1523/Jneurosci.23-07-02715.2003  0.88
2003 Craner MJ, Lo AC, Black JA, Baker D, Newcombe J, Cuzner ML, Waxman SG. Annexin II/p11 is up-regulated in Purkinje cells in EAE and MS. Neuroreport. 14: 555-8. PMID 12657884 DOI: 10.1097/00001756-200303240-00005  0.88
2003 Baker MD, Chandra SY, Ding Y, Waxman SG, Wood JN. GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones. The Journal of Physiology. 548: 373-82. PMID 12651922 DOI: 10.1113/jphysiol.2003.039131  1
2003 Black JA, Cummins TR, Yoshimura N, de Groat WC, Waxman SG. Tetrodotoxin-resistant sodium channels Na(v)1.8/SNS and Na(v)1.9/NaN in afferent neurons innervating urinary bladder in control and spinal cord injured rats. Brain Research. 963: 132-8. PMID 12560118 DOI: 10.1016/S0006-8993(02)03957-4  1
2003 Cummins TR, Renganathan M, Stys PK, Herzog RI, Scarfo K, Horn R, Dib-Hajj SD, Waxman SG. The pentapeptide QYNAD does not block voltage-gated sodium channels. Neurology. 60: 224-9. PMID 12552035 DOI: 10.1212/01.Wnl.0000042423.36650.Bd  1
2003 Renganathan M, Gelderblom M, Black JA, Waxman SG. Expression of Nav1.8 sodium channels perturbs the firing patterns of cerebellar Purkinje cells. Brain Research. 959: 235-42. PMID 12493611 DOI: 10.1016/S0006-8993(02)03750-2  0.88
2003 Liu CJ, Dib-Hajj SD, Renganathan M, Cummins TR, Waxman SG. Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B. The Journal of Biological Chemistry. 278: 1029-36. PMID 12401812 DOI: 10.1074/Jbc.M207074200  1
2003 Stys PK, Waxman SG. Ischemic White Matter Damage Myelin Biology and Disorders. 2: 985-1007. DOI: 10.1016/B978-012439510-7/50094-2  1
2002 Cummins TR, Dib-Hajj SD, Waxman SG, Donnelly DF. Characterization and developmental changes of Na+ currents of petrosal neurons with projections to the carotid body. Journal of Neurophysiology. 88: 2993-3002. PMID 12466424 DOI: 10.1152/Jn.00350.2002  1
2002 Craner MJ, Klein JP, Renganathan M, Black JA, Waxman SG. Changes of sodium channel expression in experimental painful diabetic neuropathy. Annals of Neurology. 52: 786-92. PMID 12447933 DOI: 10.1002/ana.10364  1
2002 Dib-Hajj SD, Tyrrell L, Waxman SG. Structure of the sodium channel gene SCN11A: evidence for intron-to-exon conversion model and implications for gene evolution. Molecular Neurobiology. 26: 235-50. PMID 12428758 DOI: 10.1385/MN:26:2-3:235  1
2002 Hains BC, Black JA, Waxman SG. Primary motor neurons fail to up-regulate voltage-gated sodium channel Na(v)1.3/brain type III following axotomy resulting from spinal cord injury. Journal of Neuroscience Research. 70: 546-52. PMID 12404508 DOI: 10.1002/jnr.10402  1
2002 Black JA, Renganathan M, Waxman SG. Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction. Brain Research. Molecular Brain Research. 105: 19-28. PMID 12399104 DOI: 10.1016/S0169-328X(02)00385-6  0.88
2002 Lo AC, Black JA, Waxman SG. Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis. Neuroreport. 13: 1909-12. PMID 12395089 DOI: 10.1097/00001756-200210280-00015  1
2002 Renganathan M, Dib-Hajj S, Waxman SG. Na(v)1.5 underlies the 'third TTX-R sodium current' in rat small DRG neurons. Brain Research. Molecular Brain Research. 106: 70-82. PMID 12393266 DOI: 10.1016/S0169-328X(02)00411-4  0.8
2002 Saab CY, Cummins TR, Dib-Hajj SD, Waxman SG. Molecular determinant of Na(v)1.8 sodium channel resistance to the venom from the scorpion Leiurus quinquestriatus hebraeus. Neuroscience Letters. 331: 79-82. PMID 12361845 DOI: 10.1016/S0304-3940(02)00860-1  1
2002 Craner MJ, Klein JP, Black JA, Waxman SG. Preferential expression of IGF-I in small DRG neurons and down-regulation following injury. Neuroreport. 13: 1649-52. PMID 12352620 DOI: 10.1097/00001756-200209160-00016  1
2002 Fang X, Djouhri L, Black JA, Dib-Hajj SD, Waxman SG, Lawson SN. The presence and role of the tetrodotoxin-resistant sodium channel Na(v)1.9 (NaN) in nociceptive primary afferent neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7425-33. PMID 12196564 DOI: 10.1523/Jneurosci.22-17-07425.2002  1
2002 Klein JP, Craner MJ, Cummins TR, Black JA, Waxman SG. Sodium channel expression in hypothalamic osmosensitive neurons in experimental diabetes. Neuroreport. 13: 1481-4. PMID 12167778 DOI: 10.1097/00001756-200208070-00027  1
2002 Leffler A, Cummins TR, Dib-Hajj SD, Hormuzdiar WN, Black JA, Waxman SG. GDNF and NGF reverse changes in repriming of TTX-sensitive Na(+) currents following axotomy of dorsal root ganglion neurons. Journal of Neurophysiology. 88: 650-8. PMID 12163518 DOI: 10.1152/Jn.2002.88.2.650  1
2002 Black JA, Waxman SG. Molecular identities of two tetrodotoxin-resistant sodium channels in corneal axons. Experimental Eye Research. 75: 193-9. PMID 12137764 DOI: 10.1006/exer.2002.2014  1
2002 Black JA, Dusart I, Sotelo C, Waxman SG. Axotomy does not up-regulate expression of sodium channel Na(v)1.8 in Purkinje cells. Brain Research. Molecular Brain Research. 101: 126-31. PMID 12007840 DOI: 10.1016/S0169-328X(02)00200-0  1
2002 Dib-Hajj S, Black JA, Cummins TR, Waxman SG. NaN/Nav1.9: a sodium channel with unique properties. Trends in Neurosciences. 25: 253-9. PMID 11972962 DOI: 10.1016/S0166-2236(02)02150-1  1
2002 White BH, Cummins TR, Wolf DH, Waxman SG, Russell DS, Kaczmarek LK. HSV-1 helper virus 5dl1.2 suppresses sodium currents in amplicon-transduced neurons. Journal of Neurophysiology. 87: 2149-57. PMID 11929932 DOI: 10.1152/Jn.00498.2001  1
2002 Liu CN, Devor M, Waxman SG, Kocsis JD. Subthreshold oscillations induced by spinal nerve injury in dissociated muscle and cutaneous afferents of mouse DRG. Journal of Neurophysiology. 87: 2009-17. PMID 11929919 DOI: 10.1152/jn.00705.2001  1
2002 Renganathan M, Cummins TR, Waxman SG. Nitric oxide blocks fast, slow, and persistent Na+ channels in C-type DRG neurons by S-nitrosylation. Journal of Neurophysiology. 87: 761-75. PMID 11826045 DOI: 10.1152/Jn.00369.2001  1
2002 Waxman SG, Cummins TR, Black JA, Dib-Hajj S. Diverse functions and dynamic expression of neuronal sodium channels. Novartis Foundation Symposium. 241: 34-51; discussion 51. PMID 11771649 DOI: 10.1002/0470846682.Ch4  1
2001 Sukumaran M, Waxman SG, Wood JN, Pachnis V. Flanking regulatory sequences of the locus encoding the murine GDNF receptor, c-ret, directs lac Z (beta-galactosidase) expression in developing somatosensory system. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 222: 389-402. PMID 11747074 DOI: 10.1002/dvdy.1192  1
2001 Tyrrell L, Renganathan M, Dib-Hajj SD, Waxman SG. Glycosylation alters steady-state inactivation of sodium channel Nav1.9/NaN in dorsal root ganglion neurons and is developmentally regulated. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9629-37. PMID 11739573 DOI: 10.1523/Jneurosci.21-24-09629.2001  1
2001 Liu CJ, Dib-Hajj SD, Black JA, Greenwood J, Lian Z, Waxman SG. Direct interaction with contactin targets voltage-gated sodium channel Na(v)1.9/NaN to the cell membrane. The Journal of Biological Chemistry. 276: 46553-61. PMID 11581273 DOI: 10.1074/jbc.M108699200  0.88
2001 Everill B, Cummins TR, Waxman SG, Kocsis JD. Sodium currents of large (Abeta-type) adult cutaneous afferent dorsal root ganglion neurons display rapid recovery from inactivation before and after axotomy. Neuroscience. 106: 161-9. PMID 11564426 DOI: 10.1016/S0306-4522(01)00258-5  1
2001 Herzog RI, Cummins TR, Waxman SG. Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. Journal of Neurophysiology. 86: 1351-64. PMID 11535682 DOI: 10.1152/Jn.2001.86.3.1351  1
2001 Renganathan M, Cummins TR, Waxman SG. Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. Journal of Neurophysiology. 86: 629-40. PMID 11495938 DOI: 10.1152/Jn.2001.86.2.629  1
2001 Cummins TR, Aglieco F, Renganathan M, Herzog RI, Dib-Hajj SD, Waxman SG. Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5952-61. PMID 11487618 DOI: 10.1523/Jneurosci.21-16-05952.2001  1
2001 Ghassemi F, Dib-Hajj SD, Waxman SG. Beta1 adducin gene expression in DRG is developmentally regulated and is upregulated by glial-derived neurotrophic factor and nerve growth factor. Brain Research. Molecular Brain Research. 90: 118-24. PMID 11406290 DOI: 10.1016/S0169-328X(01)00091-2  0.64
2001 Liu Cj, Dib-Hajj SD, Waxman SG. Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN). The Journal of Biological Chemistry. 276: 18925-33. PMID 11376006 DOI: 10.1074/jbc.M101606200  0.64
2001 Kearney JA, Plummer NW, Smith MR, Kapur J, Cummins TR, Waxman SG, Goldin AL, Meisler MH. A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience. 102: 307-17. PMID 11166117 DOI: 10.1016/S0306-4522(00)00479-6  0.96
2000 Waxman SG, Cummins TR, Dib-Hajj SD, Black JA. Voltage-gated sodium channels and the molecular pathogenesis of pain: a review. Journal of Rehabilitation Research and Development. 37: 517-28. PMID 11322150  1
2000 Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA. Nomenclature of voltage-gated sodium channels. Neuron. 28: 365-8. PMID 11144347 DOI: 10.1016/S0896-6273(00)00116-1  0.64
2000 Waxman SG, Dib-Hajj S, Cummins TR, Black JA. Sodium channels and their genes: dynamic expression in the normal nervous system, dysregulation in disease states(1). Brain Research. 886: 5-14. PMID 11119683 DOI: 10.1016/S0006-8993(00)02774-8  1
2000 Cummins TR, Black JA, Dib-Hajj SD, Waxman SG. Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8754-61. PMID 11102483 DOI: 10.1523/Jneurosci.20-23-08754.2000  1
2000 Cummins TR, Dib-Hajj SD, Black JA, Waxman SG. Sodium channels and the molecular pathophysiology of pain. Progress in Brain Research. 129: 3-19. PMID 11098678 DOI: 10.1016/S0079-6123(00)29002-X  1
2000 Black JA, Dib-Hajj S, Baker D, Newcombe J, Cuzner ML, Waxman SG. Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11598-602. PMID 11027357 DOI: 10.1073/pnas.97.21.11598  0.88
2000 Sleeper AA, Cummins TR, Dib-Hajj SD, Hormuzdiar W, Tyrrell L, Waxman SG, Black JA. Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7279-89. PMID 11007885 DOI: 10.1523/Jneurosci.20-19-07279.2000  1
2000 Renganathan M, Cummins TR, Hormuzdiar WN, Waxman SG. alpha-SNS produces the slow TTX-resistant sodium current in large cutaneous afferent DRG neurons. Journal of Neurophysiology. 84: 710-8. PMID 10938298 DOI: 10.1152/Jn.2000.84.2.710  1
2000 Bendahhou S, Cummins TR, Hahn AF, Langlois S, Waxman SG, Ptácek LJ. A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation. The Journal of Clinical Investigation. 106: 431-8. PMID 10930446 DOI: 10.1172/Jci9654  1
2000 Ritchie JM, Black JA, Waxman SG. Sodium channels in the cytoplasm of Schwann cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 1949. PMID 10798958  1
2000 Renganathan M, Cummins TR, Hormuzdiar WN, Black JA, Waxman SG. Nitric oxide is an autocrine regulator of Na(+) currents in axotomized C-type DRG neurons. Journal of Neurophysiology. 83: 2431-42. PMID 10758144 DOI: 10.1152/Jn.2000.83.4.2431  1
2000 Fjell J, Hjelmström P, Hormuzdiar W, Milenkovic M, Aglieco F, Tyrrell L, Dib-Hajj S, Waxman SG, Black JA. Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors. Neuroreport. 11: 199-202. PMID 10683857 DOI: 10.1097/00001756-200001170-00039  1
2000 Robert A, Howe JR, Waxman SG. Development of glutamatergic synaptic activity in cultured spinal neurons. Journal of Neurophysiology. 83: 659-70. PMID 10669482 DOI: 10.1152/Jn.2000.83.2.659  1
1999 Waxman SG, Wood JN. Sodium channels: from mechanisms to medicines? Brain Research Bulletin. 50: 309-10. PMID 10643411 DOI: 10.1016/S0361-9230(99)00158-6  0.36
1999 Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN, Waxman SG. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC43. PMID 10594087 DOI: 10.1523/Jneurosci.19-24-J0001.1999  1
1999 Dib-Hajj SD, Tyrrell L, Cummins TR, Black JA, Wood PM, Waxman SG. Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons. Febs Letters. 462: 117-20. PMID 10580103 DOI: 10.1016/S0014-5793(99)01519-7  1
1999 Dib-Hajj SD, Fjell J, Cummins TR, Zheng Z, Fried K, LaMotte R, Black JA, Waxman SG. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain. 83: 591-600. PMID 10568868 DOI: 10.1016/S0304-3959(99)00169-4  1
1999 Black JA, Cummins TR, Plumpton C, Chen YH, Hormuzdiar W, Clare JJ, Waxman SG. Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. Journal of Neurophysiology. 82: 2776-85. PMID 10561444 DOI: 10.1152/Jn.1999.82.5.2776  1
1999 Waxman SG, Cummins TR, Dib-Hajj S, Fjell J, Black JA. Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain. Muscle & Nerve. 22: 1177-87. PMID 10454712 DOI: 10.1002/(Sici)1097-4598(199909)22:9<1177::Aid-Mus3>3.0.Co;2-P  1
1999 Dib-Hajj SD, Tyrrell L, Escayg A, Wood PM, Meisler MH, Waxman SG. Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN Genomics. 59: 309-318. PMID 10444332 DOI: 10.1006/Geno.1999.5890  1
1999 Longuemare MC, Rose CR, Farrell K, Ransom BR, Waxman SG, Swanson RA. K(+)-induced reversal of astrocyte glutamate uptake is limited by compensatory changes in intracellular Na+. Neuroscience. 93: 285-92. PMID 10430492 DOI: 10.1016/S0306-4522(99)00152-9  1
1999 Fjell J, Cummins TR, Davis BM, Albers KM, Fried K, Waxman SG, Black JA. Sodium channel expression in NGF-overexpressing transgenic mice. Journal of Neuroscience Research. 57: 39-47. PMID 10397634 DOI: 10.1002/(Sici)1097-4547(19990701)57:1<39::Aid-Jnr5>3.0.Co;2-M  1
1999 Waxman SG, Dib-Hajj S, Cummins TR, Black JA. Sodium channels and pain. Proceedings of the National Academy of Sciences of the United States of America. 96: 7635-9. PMID 10393872 DOI: 10.1073/Pnas.96.14.7635  1
1999 Bendahhou S, Cummins TR, Kwiecinski H, Waxman SG, Ptácek LJ. Characterization of a new sodium channel mutation at arginine 1448 associated with moderate Paramyotonia congenita in humans. The Journal of Physiology. 518: 337-44. PMID 10381583 DOI: 10.1111/J.1469-7793.1999.0337P.X  1
1999 Black JA, Fjell J, Dib-Hajj S, Duncan ID, O'Connor LT, Fried K, Gladwell Z, Tate S, Waxman SG. Abnormal expression of SNS/PN3 sodium channel in cerebellar Purkinje cells following loss of myelin in the taiep rat. Neuroreport. 10: 913-8. PMID 10321459 DOI: 10.1097/00001756-199904060-00004  0.88
1999 Fjell J, Cummins TR, Dib-Hajj SD, Fried K, Black JA, Waxman SG. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. Brain Research. Molecular Brain Research. 67: 267-82. PMID 10216225 DOI: 10.1016/S0169-328X(99)00070-4  1
1999 Fjell J, Cummins TR, Fried K, Black JA, Waxman SG. In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons. Journal of Neurophysiology. 81: 803-10. PMID 10036280 DOI: 10.1152/Jn.1999.81.2.803  1
1999 Tanaka M, Cummins TR, Ishikawa K, Black JA, Ibata Y, Waxman SG. Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input. Proceedings of the National Academy of Sciences of the United States of America. 96: 1088-93. PMID 9927698 DOI: 10.1073/Pnas.96.3.1088  1
1999 Imaizumi T, Kocsis JD, Waxman SG. The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter. Brain Research. 817: 84-92. PMID 9889329 DOI: 10.1016/S0006-8993(98)01214-1  1
1998 Imaizumi T, Lankford KL, Waxman SG, Greer CA, Kocsis JD. Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyelinated dorsal columns of the rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6176-85. PMID 9698311 DOI: 10.1523/Jneurosci.18-16-06176.1998  1
1998 Dib-Hajj SD, Tyrrell L, Black JA, Waxman SG. NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy Proceedings of the National Academy of Sciences of the United States of America. 95: 8963-8968. PMID 9671787 DOI: 10.1073/pnas.95.15.8963  1
1998 Robert A, Black JA, Waxman SG. Endogenous NMDA-receptor activation regulates glutamate release in cultured spinal neurons Journal of Neurophysiology. 80: 196-208. PMID 9658041 DOI: 10.1152/JN.1998.80.1.196  1
1998 Black JA, Dib-Hajj S, Cohen S, Hinson AW, Waxman SG. Glial cells have heart: rH1 Na+ channel mRNA and protein in spinal cord astrocytes. Glia. 23: 200-8. PMID 9633805 DOI: 10.1002/(SICI)1098-1136(199807)23:3<200::AID-GLIA3>3.0.CO;2-8  0.88
1998 Diss JK, Stewart D, Fraser SP, Black JA, Dib-Hajj S, Waxman SG, Archer SN, Djamgoz MB. Expression of skeletal muscle-type voltage-gated Na+ channel in rat and human prostate cancer cell lines. Febs Letters. 427: 5-10. PMID 9613589 DOI: 10.1016/S0014-5793(98)00378-0  0.88
1998 Tanaka M, Cummins TR, Ishikawa K, Dib-Hajj SD, Black JA, Waxman SG. SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport. 9: 967-72. PMID 9601651 DOI: 10.1097/00001756-199804200-00003  1
1998 Dib-Hajj SD, Black JA, Cummins TR, Kenney AM, Kocsis JD, Waxman SG. Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. Journal of Neurophysiology. 79: 2668-76. PMID 9582237 DOI: 10.1152/Jn.1998.79.5.2668  1
1998 Rose CR, Waxman SG, Ransom BR. Effects of glucose deprivation, chemical hypoxia, and simulated ischemia on Na+ homeostasis in rat spinal cord astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3554-62. PMID 9570787 DOI: 10.1523/Jneurosci.18-10-03554.1998  1
1998 Lankford KL, Waxman SG, Kocsis JD. Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion. The Journal of Comparative Neurology. 391: 11-29. PMID 9527536 DOI: 10.1002/(SICI)1096-9861(19980202)391:1<11::AID-CNE2>3.0.CO;2-U  1
1998 Buschmann T, Martin-Villalba A, Kocsis JD, Waxman SG, Zimmermann M, Herdegen T. Expression of Jun, Fos, and ATF-2 proteins in axotomized explanted and cultured adult rat dorsal root ganglia. Neuroscience. 84: 163-76. PMID 9522371 DOI: 10.1016/S0306-4522(97)00487-9  1
1998 Imaizumi T, Kocsis JD, Waxman SG. Resistance to anoxic injury in the dorsal columns of adult rat spinal cord following demyelination. Brain Research. 779: 292-6. PMID 9473700 DOI: 10.1016/S0006-8993(97)01171-2  1
1998 Fern R, Davis P, Waxman SG, Ransom BR. Axon conduction and survival in CNS white matter during energy deprivation: a developmental study. Journal of Neurophysiology. 79: 95-105. PMID 9425180 DOI: 10.1152/Jn.1998.79.1.95  1
1997 Steffensen I, Waxman SG, Mills L, Stys PK. Immunolocalization of the Na(+)-Ca2+ exchanger in mammalian myelinated axons. Brain Research. 776: 1-9. PMID 9439790 DOI: 10.1016/S0006-8993(97)00868-8  1
1997 Hinson AW, Gu XQ, Dib-Hajj S, Black JA, Waxman SG. Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro. Glia. 21: 339-49. PMID 9419009 DOI: 10.1002/(SICI)1098-1136(199712)21:4<339::AID-GLIA1>3.0.CO;2-Z  1
1997 Rose CR, Ransom BR, Waxman SG. Pharmacological characterization of Na+ influx via voltage-gated Na+ channels in spinal cord astrocytes. Journal of Neurophysiology. 78: 3249-58. PMID 9405543 DOI: 10.1152/Jn.1997.78.6.3249  1
1997 Dib-Hajj SD, Ishikawa K, Cummins TR, Waxman SG. Insertion of a SNS-specific tetrapeptide in S3-S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage-gated Na channel mu1 in HEK293 cells. Febs Letters. 416: 11-4. PMID 9369222 DOI: 10.1016/S0014-5793(97)01154-X  1
1997 Ritchie JM, Black JA, Waxman SG. Sodium channels in the cytoplasm of Schwann cells. Proc. Natl. Acad. Sci. 87 (1990) 9290-9294. Brain Research. 761: 3. PMID 9247059 DOI: 10.1016/S0006-8993(97)00546-5  1
1997 Black JA, Felts P, Smith KJ, Kocsis JD, Waxman SG. Distribution of sodium channels in chronically demyelinated spinal cord axons: immunoultrastructural localization and electrophysiological observations. Brain Research 544 (1991) 59-70. Brain Research. 761: 1. PMID 9247057 DOI: 10.1016/S0006-8993(97)00544-1  1
1997 Black JA, Langworthy K, Hinson AW, Dib-Hajj SD, Waxman SG. NGF has opposing effects on Na+ channel III and SNS gene expression in spinal sensory neurons. Neuroreport. 8: 2331-5. PMID 9243635 DOI: 10.1097/00001756-199707070-00046  0.88
1997 Oyelese AA, Rizzo MA, Waxman SG, Kocsis JD. Differential effects of NGF and BDNF on axotomy-induced changes in GABA(A)-receptor-mediated conductance and sodium currents in cutaneous afferent neurons. Journal of Neurophysiology. 78: 31-42. PMID 9242258 DOI: 10.1152/Jn.1997.78.1.31  1
1997 Imaizumi T, Kocsis JD, Waxman SG. Anoxic injury in the rat spinal cord: pharmacological evidence for multiple steps in Ca(2+)-dependent injury of the dorsal columns. Journal of Neurotrauma. 14: 299-311. PMID 9199396 DOI: 10.1089/Neu.1997.14.299  1
1997 Sashihara S, Waxman SG, Greer CA. Downregulation of Na+ channel mRNA in olfactory bulb tufted cells following deafferentation. Neuroreport. 8: 1289-93. PMID 9175131 DOI: 10.1097/00001756-199703240-00046  1
1997 Gu XQ, Dib-Hajj S, Rizzo MA, Waxman SG. TTX-sensitive and -resistant Na+ currents, and mRNA for the TTX-resistant rH1 channel, are expressed in B104 neuroblastoma cells. Journal of Neurophysiology. 77: 236-46. PMID 9120565 DOI: 10.1152/JN.1997.77.1.236  1
1997 Waxman SG, Kocsis JD. Spinal cord repair: Progress towards a daunting goal Neuroscientist. 3: 263-269. DOI: 10.1177/107385849700300414  1
1996 Black JA, Dib-Hajj S, McNabola K, Jeste S, Rizzo MA, Kocsis JD, Waxman SG. Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs. Brain Research. Molecular Brain Research. 43: 117-31. PMID 9037525 DOI: 10.1016/S0169-328X(96)00163-5  1
1996 Waxman SG, Rizzo MA. The whiplash (hyperextension-flexion) syndrome: A disorder of dorsal root ganglion neurons? Journal of Neurotrauma. 13: 735-739. PMID 9002059 DOI: 10.1089/NEU.1996.13.735  1
1996 Fern R, Ransom BR, Waxman SG. Autoprotective mechanisms in the CNS: some new lessons from white matter. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 27: 107-29. PMID 8962597 DOI: 10.1007/BF02815088  1
1996 Fern R, Black JA, Ransom BR, Waxman SG. Cd(2+)-induced injury in CNS white matter. Journal of Neurophysiology. 76: 3264-73. PMID 8930271 DOI: 10.1152/Jn.1996.76.5.3264  1
1996 Roy ML, Saal D, Perney T, Sontheimer H, Waxman SG, Kaczmarek LK. Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides. Glia. 18: 177-84. PMID 8915650 DOI: 10.1002/(SICI)1098-1136(199611)18:3<177::AID-GLIA2>3.0.CO;2-X  1
1996 Gu XQ, Waxman SG. Action potential-like responses in B104 cells with low Na+ channel densities. Brain Research. 735: 50-8. PMID 8905169 DOI: 10.1016/0006-8993(96)00604-X  1
1996 Black JA, Waxman SG. Sodium channel expression: A dynamic process in neurons and non-neuronal cells Developmental Neuroscience. 18: 139-152. PMID 8894443 DOI: 10.1159/000111403  1
1996 Sontheimer H, Black JA, Waxman SG. Voltage-gated Na+ channels in gila: Properties and possible functions Trends in Neurosciences. 19: 325-331. PMID 8843601 DOI: 10.1016/0166-2236(96)10039-4  1
1996 Dib-Hajj SD, Hinson AW, Black JA, Waxman SG. Sodium channel mRNA in the B104 neuroblastoma cell line. Febs Letters. 384: 78-82. PMID 8797808 DOI: 10.1016/0014-5793(96)00273-6  0.88
1996 Waxman SG, Black JA. Expression of mRNA for a sodium channel in subfamily 2 in spinal sensory neurons Neurochemical Research. 21: 395-401. PMID 8734431 DOI: 10.1007/BF02527702  1
1996 Rizzo MA, Kocsis JD, Waxman SG. Mechanisms of paresthesiae, dysesthesiae, and hyperesthesiae: role of Na+ channel heterogeneity. European Neurology. 36: 3-12. PMID 8719643 DOI: 10.1159/000117192  1
1996 Honmou O, Felts PA, Waxman SG, Kocsis JD. Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3199-208. PMID 8627358 DOI: 10.1523/Jneurosci.16-10-03199.1996  1
1996 Sashihara S, Greer CA, Oh Y, Waxman SG. Cell-specific differential expression of Na(+)-channel beta 1-subunit mRNA in the olfactory system during postnatal development and after denervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 702-13. PMID 8551353 DOI: 10.1523/Jneurosci.16-02-00702.1996  1
1996 Fern R, Ransom BR, Waxman SG, Barinagarrementeria F, Figueroa T, Huebe J, Cantú C, Stegmayr B, Harmsen P, Rajakangas A, Rastenyté D, Sarti C, Thorvaldsen P, Tuomilehto J, Juby LC, et al. Minutes of the General Assembly of the European Stroke Council Cerebrovascular Diseases. 6: 117-117. DOI: 10.1159/000108008  1
1995 Rizzo MA, Kocsis JD, Waxman SG. Selective loss of slow and enhancement of fast Na+ currents in cutaneous afferent dorsal root ganglion neurones following axotomy. Neurobiology of Disease. 2: 87-96. PMID 8980012 DOI: 10.1006/Nbdi.1995.0009  1
1995 Black JA, Westenbroek RE, Catterall WA, Waxman SG. Type II brain sodium channel expression in non-neuronal cells: embryonic rat osteoblasts. Brain Research. Molecular Brain Research. 34: 89-98. PMID 8750864 DOI: 10.1016/0169-328X(95)00141-E  0.88
1995 Fern R, Waxman SG, Ransom BR. Endogenous GABA attenuates CNS white matter dysfunction following anoxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 699-708. PMID 7823173 DOI: 10.1523/Jneurosci.15-01-00699.1995  1
1995 Lankford KL, Rand MN, Waxman SG, Kocsis JD. Blocking Ca2+ mobilization with thapsigargin reduces neurite initiation in cultured adult rat DRG neurons. Brain Research. Developmental Brain Research. 84: 151-63. PMID 7743635 DOI: 10.1016/0165-3806(94)00159-W  1
1995 Ausim Azizi S, Fayad PB, Fulbright R, Giroux ML, Waxman SG. Clivus and cervical spinal osteomyelitis with epidural abscess presenting with multiple cranial neuropathies Clinical Neurology and Neurosurgery. 97: 239-244. PMID 7586856 DOI: 10.1016/0303-8467(95)00036-J  1
1995 Black JA, Westenbroek R, Minturn JE, Ransom BR, Catterall WA, Waxman SG. Isoform-specific expression of sodium channels in astrocytes in vitro: immunocytochemical observations. Glia. 14: 133-44. PMID 7558240 DOI: 10.1002/glia.440140208  1
1995 Felts PA, Black JA, Waxman SG. Expression of sodium channel α- and β-subunits in the nervous system of the myelin-deficient rat Journal of Neurocytology. 24: 654-666. PMID 7500121 DOI: 10.1007/BF01179816  1
1995 Fern R, Ransom BR, Waxman SG. Voltage-gated calcium channels in CNS white matter: role in anoxic injury. Journal of Neurophysiology. 74: 369-77. PMID 7472338 DOI: 10.1152/Jn.1995.74.1.369  1
1994 Utzschneider DA, Archer DR, Kocsis JD, Waxman SG, Duncan ID. Transplantation of glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin-deficient rat. Proceedings of the National Academy of Sciences of the United States of America. 91: 53-7. PMID 8278406 DOI: 10.1073/pnas.91.1.53  1
1994 Kocsis JD, Rand MN, Lankford KL, Waxman SG. Intracellular calcium mobilization and neurite outgrowth in mammalian neurons. Journal of Neurobiology. 25: 252-64. PMID 8195789 DOI: 10.1002/neu.480250306  1
1994 Utzschneider DA, Rand MN, Waxman SG, Kocsis JD. Nuclear and cytoplasmic Ca2+ signals in developing rat dorsal root ganglion neurons studied in excised tissue. Brain Research. 635: 231-7. PMID 8173960 DOI: 10.1016/0006-8993(94)91444-3  1
1994 Goldstein JM, Waxman SG, Vollmer TL, Lang B, Johnston I, Newsom-Davis J. Subacute cerebellar degeneration and Lambert-Eaton myasthenic syndrome associated with antibodies to voltagegated calcium channels: Differential effect of immunosuppressive therapy on central and peripheral defects Journal of Neurology, Neurosurgery and Psychiatry. 57: 1138-1139. PMID 8089692 DOI: 10.1136/jnnp.57.9.1138  1
1994 Oh Y, Black JA, Waxman SG. Rat brain Na+ channel mRNAs in non-excitable Schwann cells Febs Letters. 350: 342-346. PMID 8070590 DOI: 10.1016/0014-5793(94)00807-8  1
1994 Honmou O, Utzschneider DA, Rizzo MA, Bowe CM, Waxman SG, Kocsis JD. Delayed depolarization and slow sodium currents in cutaneous afferents. Journal of Neurophysiology. 71: 1627-37. PMID 8064338 DOI: 10.1152/Jn.1994.71.5.1627  1
1994 Black JA, Yokoyama S, Waxman SG, Oh Y, Zur KB, Sontheimer H, Higashida H, Ransom BR. Sodium channel mRNAs in cultured spinal cord astrocytes: in situ hybridization in identified cell types. Brain Research. Molecular Brain Research. 23: 235-45. PMID 8057780 DOI: 10.1016/0169-328X(94)90230-5  1
1994 Waxman SG, Black JA, Ransom BR, Stys PK. Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca(2+)-mediated injury in myelinated CNS axons. Brain Research. 644: 197-204. PMID 8050031 DOI: 10.1016/0006-8993(94)91680-2  1
1994 Oh Y, Black JA, Waxman SG. The expression of rat brain voltage-sensitive Na+ channel mRNAs in astrocytes Molecular Brain Research. 23: 57-65. PMID 8028484 DOI: 10.1016/0169-328X(94)90211-9  1
1994 Black JA, Yokoyama S, Higashida H, Ransom BR, Waxman SG. Sodium channel mRNAs I, II and III in the CNS: cell-specific expression. Brain Research. Molecular Brain Research. 22: 275-89. PMID 8015385 DOI: 10.1016/0169-328X(94)90056-6  1
1994 Waxman SG, Kocsis JD, Black JA. Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy. Journal of Neurophysiology. 72: 466-70. PMID 7965028 DOI: 10.1152/Jn.1994.72.1.466  1
1994 Waxman SG, Utzschneider DA, Kocsis JD. Enhancement of action potential conduction following demyelination: experimental approaches to restoration of function in multiple sclerosis and spinal cord injury. Progress in Brain Research. 100: 233-43. PMID 7938524 DOI: 10.1016/S0079-6123(08)60790-6  1
1994 Rizzo MA, Kocsis JD, Waxman SG. Slow sodium conductances of dorsal root ganglion neurons: intraneuronal homogeneity and interneuronal heterogeneity. Journal of Neurophysiology. 72: 2796-815. PMID 7897490 DOI: 10.1152/Jn.1994.72.6.2796  1
1994 Fern R, Waxman SG, Ransom BR. Modulation of anoxic injury in CNS white matter by adenosine and interaction between adenosine and GABA. Journal of Neurophysiology. 72: 2609-16. PMID 7897478 DOI: 10.1152/Jn.1994.72.6.2609  1
1994 Kocsis JD, Rand MN, Lankford K, Waxman SG. Nuclear calcium elevation may initiate neurite outgrowth in mammalian neurons. Progress in Brain Research. 103: 137-51. PMID 7886202 DOI: 10.1016/S0079-6123(08)61134-6  1
1994 Leinders-Zufall T, Rand MN, Waxman SG, Kocsis JD. Differential role of two Ca(2+)-permeable non-NMDA glutamate channels in rat retinal ganglion cells: kainate-induced cytoplasmic and nuclear Ca2+ signals. Journal of Neurophysiology. 72: 2503-16. PMID 7884475 DOI: 10.1152/Jn.1994.72.5.2503  1
1994 Black JA, Westenbroek R, Ransom BR, Catterall WA, Waxman SG. Type II sodium channels in spinal cord astrocytes in situ: immunocytochemical observations. Glia. 12: 219-27. PMID 7851989 DOI: 10.1002/glia.440120307  1
1994 Stys PK, Waxman SG. Activity-dependent modulation of excitability: implications for axonal physiology and pathophysiology. Muscle & Nerve. 17: 969-74. PMID 7520532 DOI: 10.1002/Mus.880170902  1
1993 Ransom BR, Waxman SG, Stys PK. Anoxic injury of central myelinated axons: ionic mechanisms and pharmacology. Research Publications - Association For Research in Nervous and Mental Disease. 71: 121-51. PMID 8417464  1
1993 Stys PK, Sontheimer H, Ransom BR, Waxman SG. Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons. Proceedings of the National Academy of Sciences of the United States of America. 90: 6976-80. PMID 8394004 DOI: 10.1073/Pnas.90.15.6976  1
1993 Black JA, Sontheimer H, Waxman SG. Spinal cord astrocytes in vitro: phenotypic diversity and sodium channel immunoreactivity Glia. 7: 272-285. PMID 8391514 DOI: 10.1002/glia.440070403  1
1993 Waxman SG, Sontheimer H, Black JA, Minturn JE, Ransom BR. Dynamic aspects of sodium channel expression in astrocytes. Advances in Neurology. 59: 135-55. PMID 8380514  1
1993 Fern R, Ransom BR, Stys PK, Waxman SG. Pharmacological protection of CNS white matter during anoxia: actions of phenytoin, carbamazepine and diazepam. The Journal of Pharmacology and Experimental Therapeutics. 266: 1549-55. PMID 8371157  1
1993 Waxman SG, Black JA, Ransom BR, Stys PK. Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium. Brain Research. 614: 137-45. PMID 8348309 DOI: 10.1016/0006-8993(93)91027-P  1
1993 Holloway SF, Fayad PB, Kalb RG, Guarnaccia JB, Waxman SG. Painless aortic dissection presenting as a progressive myelopathy Journal of the Neurological Sciences. 120: 141-144. PMID 8138802 DOI: 10.1016/0022-510X(93)90265-Z  1
1993 Utzschneider DA, Thio C, Sontheimer H, Ritchie JM, Waxman SG, Kocsis JD. Action potential conduction and sodium channel content in the optic nerve of the myelin-deficient rat. Proceedings. Biological Sciences / the Royal Society. 254: 245-50. PMID 8108457 DOI: 10.1098/rspb.1993.0153  1
1993 Kocsis JD, Rand MN, Chen B, Waxman SG, Pourcho R. Kainate elicits elevated nuclear calcium signals in retinal neurons via calcium-induced calcium release. Brain Research. 616: 273-82. PMID 8102939 DOI: 10.1016/0006-8993(93)90218-C  1
1993 Waxman SG, Ritchie JM. Molecular dissection of the myelinated axon. Annals of Neurology. 33: 121-36. PMID 7679565 DOI: 10.1002/ana.410330202  1
1992 Waxman SG, Black JA, Stys PK, Ransom BR. Ultrastructural concomitants of anoxic injury and early post-anoxic recovery in rat optic nerve. Brain Research. 574: 105-19. PMID 1638387 DOI: 10.1016/0006-8993(92)90806-K  1
1992 Stys PK, Waxman SG, Ransom BR. Effects of temperature on evoked electrical activity and anoxic injury in CNS white matter. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 977-86. PMID 1400652 DOI: 10.1038/Jcbfm.1992.135  1
1992 Black JA, Sontheimer H, Minturn JE, Ransom BR, Waxman SG. The expression of sodium channels in astrocytes in situ and in vitro. Progress in Brain Research. 94: 89-107. PMID 1337617 DOI: 10.1016/S0079-6123(08)61742-2  1
1992 Sontheimer H, Ransom BR, Waxman SG. Different Na+ currents in P0- and P7-derived hippocampal astrocytes in vitro: evidence for a switch in Na+ channel expression in vivo. Brain Research. 597: 24-9. PMID 1335819 DOI: 10.1016/0006-8993(92)91501-5  1
1992 Sontheimer H, Black JA, Ransom BR, Waxman SG. Ion channels in spinal cord astrocytes in vitro. I. Transient expression of high levels of Na+ and K+ channels. Journal of Neurophysiology. 68: 985-1000. PMID 1331358 DOI: 10.1152/Jn.1992.68.4.985  1
1992 Minturn JE, Sontheimer H, Black JA, Ransom BR, Waxman SG. Sodium channel expression in optic nerve astrocytes chronically deprived of axonal contact. Glia. 6: 19-29. PMID 1324888 DOI: 10.1002/glia.440060104  1
1992 Stys PK, Ransom BR, Waxman SG. Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability. Journal of Neurophysiology. 67: 236-40. PMID 1313081 DOI: 10.1152/Jn.1992.67.1.236  1
1992 Stys PK, Waxman SG, Ransom BR. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 430-9. PMID 1311030 DOI: 10.1523/Jneurosci.12-02-00430.1992  1
1992 Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD. Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Research. 592: 283-97. PMID 1280518 DOI: 10.1016/0006-8993(92)91687-A  1
1991 Sontheimer H, Waxman SG, Ransom BR. Relationship between Na+ current expression and cell-cell coupling in astrocytes cultured from rat hippocampus. Journal of Neurophysiology. 65: 989-1002. PMID 2051214 DOI: 10.1152/JN.1991.65.4.989  1
1991 Sontheimer H, Ransom BR, Cornell-Bell AH, Black JA, Waxman SG. Na(+)-current expression in rat hippocampal astrocytes in vitro: alterations during development. Journal of Neurophysiology. 65: 3-19. PMID 1999729 DOI: 10.1152/JN.1991.65.1.3  1
1991 Stys PK, Waxman SG, Ransom BR. Na(+)-Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian central nervous system white matter. Annals of Neurology. 30: 375-80. PMID 1952825 DOI: 10.1002/Ana.410300309  1
1991 Gordon TR, Kocsis JD, Waxman SG. TEA-sensitive potassium channels and inward rectification in regenerated rat sciatic nerve. Muscle & Nerve. 14: 640-6. PMID 1922170 DOI: 10.1002/mus.880140707  1
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