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Christopher D Nelson, PhD - Publications

Affiliations: 
2001-2007 Biochemistry Duke University, Durham, NC 
 2008-2009 Neuroscience Massachusetts Institute of Technology, Cambridge, MA, United States 
 2009-2013 Neuroscience Genentech, Inc., San Francisco, CA, United States 
 2014- Diagnostics Roche, Indianapolis, IN, United States 
Area:
GPCRs, arrestin, neuroscience, diagnostics
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Nelson CD, Sheng M. Gpr3 stimulates Aβ production via interactions with APP and β-arrestin2. Plos One. 8: e74680. PMID 24069330 DOI: 10.1371/journal.pone.0074680  0.609
2013 Nelson CD, Kim MJ, Hsin H, Chen Y, Sheng M. Phosphorylation of threonine-19 of PSD-95 by GSK-3β is required for PSD-95 mobilization and long-term depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12122-35. PMID 23864697 DOI: 10.1523/JNEUROSCI.0131-13.2013  0.52
2012 Boudreau AC, Milovanovic M, Conrad KL, Nelson C, Ferrario CR, Wolf ME. A protein cross-linking assay for measuring cell surface expression of glutamate receptor subunits in the rodent brain after in vivo treatments. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.30.1-19. PMID 22470150 DOI: 10.1002/0471142301.Ns0530S59  0.303
2011 Chen X, Nelson CD, Li X, Winters CA, Azzam R, Sousa AA, Leapman RD, Gainer H, Sheng M, Reese TS. PSD-95 is required to sustain the molecular organization of the postsynaptic density. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6329-38. PMID 21525273 DOI: 10.1523/Jneurosci.5968-10.2011  0.502
2008 Ozawa K, Whalen EJ, Nelson CD, Mu Y, Hess DT, Lefkowitz RJ, Stamler JS. S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking. Molecular Cell. 31: 395-405. PMID 18691971 DOI: 10.1016/J.Molcel.2008.05.024  0.866
2008 Nelson CD, Kovacs JJ, Nobles KN, Whalen EJ, Lefkowitz RJ. Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 21093-101. PMID 18534983 DOI: 10.1074/Jbc.M800431200  0.786
2007 Whalen EJ, Foster MW, Matsumoto A, Ozawa K, Violin JD, Que LG, Nelson CD, Benhar M, Keys JR, Rockman HA, Koch WJ, Daaka Y, Lefkowitz RJ, Stamler JS. Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell. 129: 511-22. PMID 17482545 DOI: 10.1016/J.Cell.2007.02.046  0.79
2007 Nelson CD, Perry SJ, Regier DS, Prescott SM, Topham MK, Lefkowitz RJ. Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science (New York, N.Y.). 315: 663-6. PMID 17272726 DOI: 10.1126/Science.1134562  0.795
2006 Gesty-Palmer D, Chen M, Reiter E, Ahn S, Nelson CD, Wang S, Eckhardt AE, Cowan CL, Spurney RF, Luttrell LM, Lefkowitz RJ. Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. The Journal of Biological Chemistry. 281: 10856-64. PMID 16492667 DOI: 10.1074/Jbc.M513380200  0.79
2006 Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. The Journal of Biological Chemistry. 281: 1261-73. PMID 16280323 DOI: 10.1074/Jbc.M506576200  0.845
2004 Chen W, Ren XR, Nelson CD, Barak LS, Chen JK, Beachy PA, de Sauvage F, Lefkowitz RJ. Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. Science (New York, N.Y.). 306: 2257-60. PMID 15618519 DOI: 10.1126/Science.1104135  0.866
2003 Chen W, Kirkbride KC, How T, Nelson CD, Mo J, Frederick JP, Wang XF, Lefkowitz RJ, Blobe GC. Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling. Science (New York, N.Y.). 301: 1394-7. PMID 12958365 DOI: 10.1126/Science.1083195  0.842
2003 Wu JH, Peppel K, Nelson CD, Lin FT, Kohout TA, Miller WE, Exum ST, Freedman NJ. The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. The Journal of Biological Chemistry. 278: 44238-45. PMID 12944399 DOI: 10.1074/Jbc.M309450200  0.797
2003 Miller WE, Houtz DA, Nelson CD, Kolattukudy PE, Lefkowitz RJ. G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR. The Journal of Biological Chemistry. 278: 21663-71. PMID 12668664 DOI: 10.1074/Jbc.M303219200  0.834
2003 Ahn S, Nelson CD, Garrison TR, Miller WE, Lefkowitz RJ. Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference. Proceedings of the National Academy of Sciences of the United States of America. 100: 1740-4. PMID 12582207 DOI: 10.1073/Pnas.262789099  0.841
1997 Luoh SM, Di Marco F, Levin N, Armanini M, Xie MH, Nelson C, Bennett GL, Williams M, Spencer SA, Gurney A, de Sauvage FJ. Cloning and characterization of a human leptin receptor using a biologically active leptin immunoadhesin. Journal of Molecular Endocrinology. 18: 77-85. PMID 9061609 DOI: 10.1677/Jme.0.0180077  0.377
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