| Year |
Citation |
Score |
| 2022 |
Fonseca FV, Raffay TM, Xiao K, McLaughlin PJ, Qian Z, Grimmett ZW, Adachi N, Wang B, Hausladen A, Cobb BA, Zhang R, Hess DT, Gaston B, Lambert NA, Reynolds JD, et al. S-nitrosylation is required for βAR desensitization and experimental asthma. Molecular Cell. PMID 35931084 DOI: 10.1016/j.molcel.2022.06.033 |
0.332 |
|
| 2021 |
He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, et al. Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nature Communications. 12: 2396. PMID 33888704 DOI: 10.1038/s41467-021-22731-x |
0.357 |
|
| 2020 |
Liu Q, He QT, Lyu X, Yang F, Zhu ZL, Xiao P, Yang Z, Zhang F, Yang ZY, Wang XY, Sun P, Wang QW, Qu CX, Gong Z, Lin JY, ... ... Xiao KH, et al. DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe. Nature Communications. 11: 4857. PMID 32978402 DOI: 10.1038/s41467-020-18433-5 |
0.363 |
|
| 2020 |
Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, et al. Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature Chemical Biology. PMID 32632293 DOI: 10.1038/S41589-020-0567-0 |
0.526 |
|
| 2020 |
White AD, Jean-Alphonse FG, Fang F, Peña KA, Liu S, König GM, Inoue A, Aslanoglou D, Gellman SH, Kostenis E, Xiao K, Vilardaga JP. G-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR. Proceedings of the National Academy of Sciences of the United States of America. PMID 32184323 DOI: 10.1073/Pnas.1918158117 |
0.49 |
|
| 2019 |
Liu H, Wang D, Zhang Q, Zhao Y, Mamonova T, Wang L, Zhang C, Li S, Friedman PA, Xiao K. Parallel PTM scanning enhances HDXMS coverage of key structural regions. Analytical Chemistry. PMID 31082219 DOI: 10.1021/Acs.Analchem.9B01410 |
0.417 |
|
| 2019 |
Zhao Y, Xiao K. A Mass Spectrometry-Based Structural Assay for Activation-Dependent Conformational Changes in β-Arrestins. Methods in Molecular Biology (Clifton, N.J.). 1957: 293-308. PMID 30919361 DOI: 10.1007/978-1-4939-9158-7_18 |
0.318 |
|
| 2019 |
White AD, Fang F, Jean-Alphonse FG, Clark LJ, An HJ, Liu H, Zhao Y, Reynolds SL, Lee S, Xiao K, Sutkeviciute I, Vilardaga JP. Ca allostery in PTH-receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718391 DOI: 10.1073/Pnas.1814670116 |
0.463 |
|
| 2019 |
Zhang Q, Xiao K, Paredes JM, Mamonova T, Sneddon WB, Liu H, Wang D, Li S, McGarvey JC, Uehling D, Al-Awar R, Joseph B, Jean-Alphonse F, Orte A, Friedman PA. Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport. The Journal of Biological Chemistry. PMID 30696771 DOI: 10.1074/Jbc.Ra119.007421 |
0.398 |
|
| 2019 |
White A, Sutkeviciute I, Jean-Alphonse F, Xiao K, Vilardaga J. MON-538 Ca2+Allostery in PTH-Receptor Signaling Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-538 |
0.383 |
|
| 2018 |
Xiao K, Zhao Y, Choi M, Liu H, Blanc A, Qian J, Cahill TJ, Li X, Xiao Y, Clark LJ, Li S. Revealing the architecture of protein complexes by an orthogonal approach combining HDXMS, CXMS, and disulfide trapping. Nature Protocols. 13: 1403-1428. PMID 29844522 DOI: 10.1038/Nprot.2018.037 |
0.375 |
|
| 2018 |
Zhang Q, Xiao K, Liu H, Song L, McGarvey JC, Sneddon WB, Bisello A, Friedman PA. Site-specific polyubiquitination differentially regulates parathyroid hormone receptor-initiated MAPK signaling and cell proliferation. The Journal of Biological Chemistry. PMID 29444827 DOI: 10.1074/Jbc.Ra118.001737 |
0.487 |
|
| 2017 |
Xiao K, Sun J. Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics. Cellular Signalling. PMID 28939107 DOI: 10.1016/J.Cellsig.2017.09.013 |
0.443 |
|
| 2017 |
Mamonova T, Zhang Q, Chandra M, Collins B, Sarfo EK, Bu Z, Xiao K, Bisello A, Friedman PA. Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor. Biochemistry. PMID 28376304 DOI: 10.1021/Acs.Biochem.7B00078 |
0.414 |
|
| 2017 |
Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, ... ... Xiao KH, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling. Nature Communications. 8: 14335. PMID 28181498 DOI: 10.1038/Ncomms14335 |
0.392 |
|
| 2016 |
Jean-Alphonse FG, Wehbi VL, Chen J, Noda M, Taboas JM, Xiao K, Vilardaga JP. β2-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ. Nature Chemical Biology. PMID 28024151 DOI: 10.1038/Nchembio.2267 |
0.563 |
|
| 2016 |
Liu H, Zhang Q, Li K, Gong Z, Liu Z, Xu Y, Swaney MH, Xiao K, Chen Y. Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling. Oncotarget. PMID 27835898 DOI: 10.18632/Oncotarget.13219 |
0.393 |
|
| 2016 |
Sneddon WB, Ruiz GW, Gallo LI, Xiao K, Zhang Q, Rbaibi Y, Weisz OA, Apodaca GL, Friedman PA. Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport. The Journal of Biological Chemistry. PMID 27432882 DOI: 10.1074/Jbc.M116.744052 |
0.331 |
|
| 2016 |
Tillman TS, Alvarez FJ, Reinert NJ, Liu C, Wang D, Xu Y, Xiao K, Zhang P, Tang P. Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from E. coli. The Journal of Biological Chemistry. PMID 27385587 DOI: 10.1074/Jbc.M116.729970 |
0.402 |
|
| 2016 |
Watson LJ, Alexander KM, Mohan ML, Bowman AL, Mangmool S, Xiao K, Prasad SV, Rockman HA. Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor mediated EGFR transactivation. Cellular Signalling. PMID 27169346 DOI: 10.1016/J.Cellsig.2016.05.006 |
0.408 |
|
| 2016 |
McGarvey JC, Xiao K, Bowman SL, Mamonova T, Zhang Q, Bisello A, Sneddon WB, Ardura JA, Jean-Alphonse F, Vilardaga JP, Puthenveedu MA, Friedman PA. Actin-Sorting Nexin 27-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling. The Journal of Biological Chemistry. PMID 27008860 DOI: 10.1074/Jbc.M115.697045 |
0.448 |
|
| 2016 |
Gidon A, Feinstein TN, Xiao K, Vilardaga JP. Studying the regulation of endosomal cAMP production in GPCR signaling. Methods in Cell Biology. 132: 109-26. PMID 26928541 DOI: 10.1016/Bs.Mcb.2015.10.007 |
0.375 |
|
| 2015 |
Li A, Yang D, Zhu M, Tsai KC, Xiao KH, Yu X, Sun J, Du L. Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics. Future Medicinal Chemistry. PMID 26653412 DOI: 10.4155/Fmc.15.160 |
0.434 |
|
| 2015 |
Yang F, Yu X, Liu C, Qu CX, Gong Z, Liu HD, Li FH, Wang HM, He DF, Yi F, Song C, Tian CL, Xiao KH, Wang JY, Sun JP. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nature Communications. 6: 8202. PMID 26347956 DOI: 10.1038/Ncomms9202 |
0.479 |
|
| 2014 |
Wang HM, Xu YF, Ning SL, Yang DX, Li Y, Du YJ, Yang F, Zhang Y, Liang N, Yao W, Zhang LL, Gu LC, Gao CJ, Pang Q, Chen YX, ... Xiao KH, et al. The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes. Cell Research. 24: 1067-90. PMID 25081058 DOI: 10.1038/Cr.2014.99 |
0.378 |
|
| 2014 |
Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, et al. Visualization of arrestin recruitment by a G-protein-coupled receptor. Nature. 512: 218-22. PMID 25043026 DOI: 10.1038/Nature13430 |
0.539 |
|
| 2014 |
Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/Nprot.2014.075 |
0.417 |
|
| 2014 |
Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ. Recent developments in biased agonism. Current Opinion in Cell Biology. 27: 18-24. PMID 24680426 DOI: 10.1016/J.Ceb.2013.10.008 |
0.448 |
|
| 2013 |
Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, et al. Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature. 497: 137-41. PMID 23604254 DOI: 10.1038/Nature12120 |
0.572 |
|
| 2013 |
Tang H, Xiao K, Mao L, Rockman HA, Marchuk DA. Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 54: 101-11. PMID 23085512 DOI: 10.1016/J.Yjmcc.2012.10.004 |
0.303 |
|
| 2012 |
Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK. MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors. The Journal of Cell Biology. 199: 817-30. PMID 23166351 DOI: 10.1083/Jcb.201208192 |
0.39 |
|
| 2012 |
Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/Pnas.1211889109 |
0.43 |
|
| 2011 |
Sarker S, Xiao K, Shenoy SK. A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains. Communicative & Integrative Biology. 4: 528-31. PMID 22046454 DOI: 10.4161/Cib.4.5.16458 |
0.706 |
|
| 2011 |
Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51. PMID 21868357 DOI: 10.1126/Scisignal.2001707 |
0.552 |
|
| 2011 |
Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/Nchembio.634 |
0.524 |
|
| 2011 |
Shukla AK, Xiao K, Lefkowitz RJ. Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. Trends in Biochemical Sciences. 36: 457-69. PMID 21764321 DOI: 10.1016/J.Tibs.2011.06.003 |
0.551 |
|
| 2011 |
Xiao K, Shenoy SK. β2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains Journal of Biological Chemistry. 286: 12785-12795. PMID 21330366 DOI: 10.1074/Jbc.M110.203091 |
0.502 |
|
| 2011 |
Sarker S, Xiao K, Shenoy SK. A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains Communicative and Integrative Biology. 4: 528-531. DOI: 10.4161/cib.4.5.16458 |
0.506 |
|
| 2011 |
Sarker S, Xiao K, Shenoy SK. A Tale of Two Sites – How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains Communicative & Integrative Biology. 4: 528-531. DOI: 10.4161/Cib.16458 |
0.686 |
|
| 2010 |
Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proceedings of the National Academy of Sciences of the United States of America. 107: 15299-304. PMID 20686112 DOI: 10.1073/Pnas.1008461107 |
0.451 |
|
| 2010 |
Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ. Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. The Journal of Biological Chemistry. 285: 30115-25. PMID 20650893 DOI: 10.1074/Jbc.M110.141549 |
0.538 |
|
| 2009 |
Xie L, Xiao K, Whalen EJ, Forrester MT, Freeman RS, Fong G, Gygi SP, Lefkowitz RJ, Stamler JS. Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Science Signaling. 2: ra33. PMID 19584355 DOI: 10.1126/Scisignal.2000444 |
0.481 |
|
| 2009 |
Shenoy SK, Modi AS, Shukla AK, Xiao K, Berthouze M, Ahn S, Wilkinson KD, Miller WE, Lefkowitz RJ. Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 106: 6650-5. PMID 19363159 DOI: 10.1073/Pnas.0901083106 |
0.404 |
|
| 2009 |
Petrotchenko EV, Xiao K, Cable J, Chen Y, Dokholyan NV, Borchers CH. BiPS, a photocleavable, isotopically coded, fluorescent cross-linker for structural proteomics. Molecular & Cellular Proteomics : McP. 8: 273-86. PMID 18838738 DOI: 10.1074/Mcp.M800265-Mcp200 |
0.316 |
|
| 2008 |
Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM. Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 22166-76. PMID 18544533 DOI: 10.1074/Jbc.M709668200 |
0.359 |
|
| 2008 |
Kovacs JJ, Whalen EJ, Liu R, Xiao K, Kim J, Chen M, Wang J, Chen W, Lefkowitz RJ. Beta-arrestin-mediated localization of smoothened to the primary cilium. Science (New York, N.Y.). 320: 1777-81. PMID 18497258 DOI: 10.1126/Science.1157983 |
0.361 |
|
| 2007 |
Shenoy SK, Barak LS, Xiao K, Ahn S, Berthouze M, Shukla AK, Luttrell LM, Lefkowitz RJ. Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. The Journal of Biological Chemistry. 282: 29549-62. PMID 17666399 DOI: 10.1074/Jbc.M700852200 |
0.364 |
|
| 2007 |
Xiao K, McClatchy DB, Shukla AK, Zhao Y, Chen M, Shenoy SK, Yates JR, Lefkowitz RJ. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12011-6. PMID 17620599 DOI: 10.1073/Pnas.0704849104 |
0.455 |
|
| 2007 |
Nobles KN, Guan Z, Xiao K, Oas TG, Lefkowitz RJ. The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2. The Journal of Biological Chemistry. 282: 21370-81. PMID 17513300 DOI: 10.1074/Jbc.M611483200 |
0.361 |
|
| 2006 |
Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. The Journal of Biological Chemistry. 281: 1261-73. PMID 16280323 DOI: 10.1074/Jbc.M506576200 |
0.449 |
|
| 2004 |
Xiao K, Liu X, Yu CA, Yu L. The extra fragment of the iron-sulfur protein (residues 96-107) of Rhodobacter sphaeroides cytochrome bc1 complex is required for protein stability. Biochemistry. 43: 1488-95. PMID 14769025 DOI: 10.1021/Bi035378Z |
0.311 |
|
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