Nils Brose - Publications

Affiliations: 
Max-Planck-Institute for Experimental Medicine, Göttingen, Germany 
Area:
synapse formation and function

212 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 López-Murcia FJ, Reim K, Jahn O, Taschenberger H, Brose N. Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release. Cell Reports. 26: 2521-2530.e5. PMID 30840877 DOI: 10.1016/j.celrep.2019.02.030  0.72
2019 Scholz N, Ehmann N, Sachidanandan D, Imig C, Cooper BH, Jahn O, Reim K, Brose N, Meyer J, Lamberty M, Altrichter S, Bormann A, Hallermann S, Pauli M, Heckmann M, et al. Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix. The Journal of Cell Biology. PMID 30782781 DOI: 10.1083/jcb.201806155  0.72
2018 Babaev O, Cruces-Solis H, Piletti Chatain C, Hammer M, Wenger S, Ali H, Karalis N, de Hoz L, Schlüter OM, Yanagawa Y, Ehrenreich H, Taschenberger H, Brose N, Krueger-Burg D. IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses. Nature Communications. 9: 5400. PMID 30573727 DOI: 10.1038/s41467-018-07762-1  0.6
2018 Neher E, Brose N. Dynamically Primed Synaptic Vesicle States: Key to Understand Synaptic Short-Term Plasticity. Neuron. 100: 1283-1291. PMID 30571941 DOI: 10.1016/j.neuron.2018.11.024  1
2018 Bhouri M, Morishita W, Temkin P, Goswami D, Kawabe H, Brose N, Südhof TC, Craig AM, Siddiqui TJ, Malenka R. Deletion of in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 29784826 DOI: 10.1073/pnas.1803280115  1
2018 Daniel JA, Cooper BH, Palvimo JJ, Zhang FP, Brose N, Tirard M. Response: Commentary: Analysis of SUMO1-conjugation at synapses. Frontiers in Cellular Neuroscience. 12: 117. PMID 29766991 DOI: 10.3389/fncel.2018.00117  0.64
2018 Zhang B, Gokce O, Hale WD, Brose N, Südhof TC. Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses. The Journal of Experimental Medicine. PMID 29724786 DOI: 10.1084/jem.20172162  0.72
2018 Peters F, Salihoglu H, Rodrigues E, Herzog E, Blume T, Filser S, Dorostkar M, Shimshek DR, Brose N, Neumann U, Herms J. BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology. Acta Neuropathologica. PMID 29327084 DOI: 10.1007/s00401-017-1804-9  0.68
2017 Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, ... ... Brose N, et al. Building Bridges through Science. Neuron. 96: 730-735. PMID 29144972 DOI: 10.1016/j.neuron.2017.09.028  1
2017 Unichenko P, Yang JW, Kirischuk S, Kolbaev S, Kilb W, Hammer M, Krueger-Burg D, Brose N, Luhmann HJ. Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex. Cerebral Cortex (New York, N.Y. : 1991). 1-14. PMID 29106499 DOI: 10.1093/cercor/bhx165  0.6
2017 Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT. Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18. Neuron. 95: 591-607.e10. PMID 28772123 DOI: 10.1016/j.neuron.2017.07.004  0.64
2017 Daniel JA, Cooper BH, Palvimo JJ, Zhang FP, Brose N, Tirard M. Analysis of SUMO1-conjugation at Synapses. Elife. 6. PMID 28598330 DOI: 10.7554/eLife.26338  0.64
2017 Krueger-Burg D, Papadopoulos T, Brose N. Organizers of inhibitory synapses come of age. Current Opinion in Neurobiology. 45: 66-77. PMID 28460365 DOI: 10.1016/j.conb.2017.04.003  0.52
2017 Chehab T, Santos NC, Holthenrich A, Koerdt SN, Disse J, Schuberth C, Nazmi AR, Neeft M, Koch H, Man KNM, Wojcik SM, Martin TFJ, van der Sluijs P, Brose N, Gerke V. A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Molecular Biology of the Cell. 28: 1688-1700. PMID 28450451 DOI: 10.1091/mbc.E17-02-0128  1
2017 Sigler A, Oh WC, Imig C, Altas B, Kawabe H, Cooper BH, Kwon HB, Rhee JS, Brose N. Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release. Neuron. 94: 304-311.e4. PMID 28426965 DOI: 10.1016/j.neuron.2017.03.029  1
2017 Kawabe H, Mitkovski M, Kaeser PS, Hirrlinger J, Opazo F, Nestvogel D, Kalla S, Fejtova A, Verrier SE, Bungers SR, Cooper BH, Varoqueaux F, Wang Y, Nehring RB, Gundelfinger ED, ... ... Brose N, et al. Correction: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology. PMID 28289090 DOI: 10.1083/jcb.20160608603092017c  1
2017 Kawabe H, Mitkovski M, Kaeser PS, Hirrlinger J, Opazo F, Nestvogel D, Kalla S, Fejtova A, Verrier SE, Bungers SR, Varoqueaux F, Wang Y, Nehring RB, Gundelfinger ED, Rosenmund C, ... ... Brose N, et al. ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology. PMID 28264913 DOI: 10.1083/jcb.201606086  1
2017 Ripamonti S, Ambrozkiewicz MC, Guzzi F, Gravati M, Biella G, Bormuth I, Hammer M, Tuffy LP, Sigler A, Kawabe H, Nishimori K, Toselli M, Brose N, Parenti M, Rhee J. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. Elife. 6. PMID 28231043 DOI: 10.7554/eLife.22466  1
2017 Lipstein N, Verhoeven-Duif NM, Michelassi FE, Calloway N, van Hasselt PM, Pienkowska K, van Haaften G, van Haelst MM, van Empelen R, Cuppen I, van Teeseling HC, Evelein AM, Vorstman JA, Thoms S, Jahn O, ... ... Brose N, et al. Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. The Journal of Clinical Investigation. PMID 28192369 DOI: 10.1172/JCI90259  0.72
2017 Lahut S, Gispert S, Ömür Ö, Depboylu C, Seidel K, Domínguez-Bautista JA, Brehm N, Tireli H, Hackmann K, Pirkevi C, Leube B, Ries V, Reim K, Brose N, den Dunnen WF, et al. Blood RNA biomarkers in prodromal PARK4 and REM sleep behavior disorder show role of complexin-1 loss for risk of Parkinson's disease. Disease Models & Mechanisms. PMID 28108469 DOI: 10.1242/dmm.028035  0.72
2016 Schreiner D, Savas JN, Herzog E, Brose N, de Wit J. Synapse biology in the 'circuit-age'-paths toward molecular connectomics. Current Opinion in Neurobiology. 42: 102-110. PMID 28033531 DOI: 10.1016/j.conb.2016.12.004  0.68
2016 Papadopoulos T, Rhee HJ, Subramanian D, Paraskevopoulou F, Mueller R, Schultz C, Brose N, Rhee JS, Betz H. Endosomal Phosphatidylinositol-3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses. The Journal of Biological Chemistry. PMID 27941024 DOI: 10.1074/jbc.M116.771592  0.72
2016 Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D. Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology. PMID 27454932 DOI: 10.1038/nchembio.2141  1
2016 Babai N, Sendelbeck A, Regus-Leidig H, Fuchs M, Mertins J, Reim K, Brose N, Feigenspan A, Brandstätter JH. Functional Roles of Complexin3 and Complexin4 at Mouse Photoreceptor Ribbon Synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6651-67. PMID 27335398 DOI: 10.1523/JNEUROSCI.4335-15.2016  0.72
2016 Mortensen LS, Park SJ, Ke JB, Cooper BH, Zhang L, Imig C, Löwel S, Reim K, Brose N, Demb JB, Rhee JS, Singer JH. Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses. Cell Reports. PMID 27239031 DOI: 10.1016/j.celrep.2016.05.012  1
2016 Okamoto Y, Lipstein N, Hua Y, Lin KH, Brose N, Sakaba T, Midorikawa M. Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice. Elife. 5. PMID 27154627 DOI: 10.7554/eLife.14643  1
2015 Wüstefeld L, Winkler D, Janc OA, Hassouna I, Ronnenberg A, Ostmeier K, Müller M, Brose N, Ehrenreich H, Wojcik SM. Selective expression of a constitutively active erythropoietin receptor in GABAergic neurons alters hippocampal network properties without affecting cognition. Journal of Neurochemistry. PMID 26613978 DOI: 10.1111/jnc.13445  1
2015 Man KM, Imig C, Walter AM, Pinheiro PS, Stevens DR, Rettig J, Sørensen JB, Cooper BH, Brose N, Wojcik SM. Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis. Elife. 4. PMID 26575293 DOI: 10.7554/eLife.10635  1
2015 Ludolphs M, Schneeberger D, Soykan T, Schäfer J, Papadopoulos T, Brose N, Schindelin H, Steinem C. Specificity of collybistin-phosphoinositide interactions: Impact of the individual protein domains. The Journal of Biological Chemistry. PMID 26546675 DOI: 10.1074/jbc.M115.673400  1
2015 Hammer M, Krueger-Burg D, Tuffy LP, Cooper BH, Taschenberger H, Goswami SP, Ehrenreich H, Jonas P, Varoqueaux F, Rhee JS, Brose N. Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism. Cell Reports. 13: 516-23. PMID 26456829 DOI: 10.1016/j.celrep.2015.09.011  1
2015 Lipina TV, Prasad T, Yokomaku D, Luo L, Connor SA, Kawabe H, Tian Wang Y, Brose N, Roder JC, Marie Craig A. Cognitive Deficits in Calsyntenin-2 Deficient Mice Associated with Reduced Gabaergic Transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26171716 DOI: 10.1038/npp.2015.206  1
2015 Babaev O, Botta P, Meyer E, Müller C, Ehrenreich H, Brose N, Lüthi A, Krueger-Burg D. Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala. Neuropharmacology. PMID 26142252 DOI: 10.1016/j.neuropharm.2015.06.016  0.52
2015 Schotten S, Meijer M, Walter AM, Huson V, Mamer L, Kalogreades L, Veer MT, Ruiter M, Brose N, Rosenmund C, Sørensen JB, Verhage M, Cornelisse LN. Correction: Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate. Elife. 4. PMID 26041332 DOI: 10.7554/eLife.09036  1
2015 Chang S, Reim K, Pedersen M, Neher E, Brose N, Taschenberger H. Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8272-90. PMID 26019341 DOI: 10.1523/JNEUROSCI.4841-14.2015  1
2015 Schotten S, Meijer M, Walter AM, Huson V, Mamer L, Kalogreades L, ter Veer M, Ruiter M, Brose N, Rosenmund C, Sørensen JB, Verhage M, Cornelisse LN. Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate. Elife. 4: e05531. PMID 25871846 DOI: 10.7554/eLife.05531  1
2015 Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW. Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain Structure & Function. 220: 47-58. PMID 25713840 DOI: 10.1007/s00429-013-0636-1  1
2015 Papadopoulos T, Schemm R, Grubmüller H, Brose N. Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability. The Journal of Biological Chemistry. 290: 8256-70. PMID 25678704 DOI: 10.1074/jbc.M114.633024  1
2015 Netrakanti PR, Cooper BH, Dere E, Poggi G, Winkler D, Brose N, Ehrenreich H. Fast cerebellar reflex circuitry requires synaptic vesicle priming by munc13-3. Cerebellum (London, England). 14: 264-83. PMID 25617111 DOI: 10.1007/s12311-015-0645-0  1
2015 Vogl C, Cooper BH, Neef J, Wojcik SM, Reim K, Reisinger E, Brose N, Rhee JS, Moser T, Wichmann C. Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells. Journal of Cell Science. 128: 638-44. PMID 25609709 DOI: 10.1242/jcs.162099  1
2015 Babaev O, Botta P, Meyer E, Müller C, Ehrenreich H, Brose N, Lüthi A, Krueger-Burg D. Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala Neuropharmacology. DOI: 10.1016/j.neuropharm.2015.06.016  1
2014 Nguyen Truong CQ, Nestvogel D, Ratai O, Schirra C, Stevens DR, Brose N, Rhee J, Rettig J. Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain. Cell Reports. 9: 902-9. PMID 25437547 DOI: 10.1016/j.celrep.2014.09.050  1
2014 Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, Südhof TC, Rhee J, Brose N, Cooper BH. The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron. 84: 416-31. PMID 25374362 DOI: 10.1016/j.neuron.2014.10.009  1
2014 Ishiyama S, Schmidt H, Cooper BH, Brose N, Eilers J. Munc13-3 superprimes synaptic vesicles at granule cell-to-basket cell synapses in the mouse cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14687-96. PMID 25355221 DOI: 10.1523/JNEUROSCI.2060-14.2014  1
2014 Hsia HE, Kumar R, Luca R, Takeda M, Courchet J, Nakashima J, Wu S, Goebbels S, An W, Eickholt BJ, Polleux F, Rotin D, Wu H, Rossner MJ, Bagni C, ... ... Brose N, et al. Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth. Proceedings of the National Academy of Sciences of the United States of America. 111: 13205-10. PMID 25157163 DOI: 10.1073/pnas.1400737111  1
2014 Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N. A conformational switch in collybistin determines the differentiation of inhibitory postsynapses. The Embo Journal. 33: 2113-33. PMID 25082542 DOI: 10.15252/embj.201488143  1
2014 Ju A, Hammerschmidt K, Tantra M, Krueger D, Brose N, Ehrenreich H. Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism. Behavioural Brain Research. 270: 159-64. PMID 24855039 DOI: 10.1016/j.bbr.2014.05.019  1
2014 Dhara M, Yarzagaray A, Schwarz Y, Dutta S, Grabner C, Moghadam PK, Bost A, Schirra C, Rettig J, Reim K, Brose N, Mohrmann R, Bruns D. Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics. The Journal of Cell Biology. 204: 1123-40. PMID 24687280 DOI: 10.1083/jcb.201311085  1
2014 Brose N. All roads lead to neuroscience: the 2013 Nobel Prize in Physiology or Medicine. Neuron. 81: 723-7. PMID 24559668 DOI: 10.1016/j.neuron.2014.02.008  1
2014 Kleijer KT, Schmeisser MJ, Krueger DD, Boeckers TM, Scheiffele P, Bourgeron T, Brose N, Burbach JP. Neurobiology of autism gene products: towards pathogenesis and drug targets. Psychopharmacology. 231: 1037-62. PMID 24419271 DOI: 10.1007/s00213-013-3403-3  1
2014 Biesemann C, Grønborg M, Luquet E, Wichert SP, Bernard V, Bungers SR, Cooper B, Varoqueaux F, Li L, Byrne JA, Urlaub H, Jahn O, Brose N, Herzog E. Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. The Embo Journal. 33: 157-70. PMID 24413018 DOI: 10.1002/embj.201386120  1
2014 Imig C, Min SW, Krinner S, Arancillo M, Rosenmund C, Südhof TC, Rhee J, Brose N, Cooper BH. Correction to The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones[Neuron, (2014), 84, 416-431] Neuron. 84: 882. DOI: 10.1016/j.neuron.2014.11.003  1
2013 Ferro-Novick S, Brose N. Nobel 2013 Physiology or medicine: Traffic control system within cells. Nature. 504: 98. PMID 24305158 DOI: 10.1038/504098a  1
2013 Mayer S, Kumar R, Jaiswal M, Soykan T, Ahmadian MR, Brose N, Betz H, Rhee JS, Papadopoulos T. Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 110: 20795-800. PMID 24297911 DOI: 10.1073/pnas.1309078110  1
2013 Pettem KL, Yokomaku D, Luo L, Linhoff MW, Prasad T, Connor SA, Siddiqui TJ, Kawabe H, Chen F, Zhang L, Rudenko G, Wang YT, Brose N, Craig AM. The specific α-neurexin interactor calsyntenin-3 promotes excitatory and inhibitory synapse development. Neuron. 80: 113-28. PMID 24094106 DOI: 10.1016/j.neuron.2013.07.016  1
2013 Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW. Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain Structure & Function. PMID 24077800 DOI: 10.1007/s00429-013-0636-1  0.96
2013 Siddiqui TJ, Tari PK, Connor SA, Zhang P, Dobie FA, She K, Kawabe H, Wang YT, Brose N, Craig AM. An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells. Neuron. 79: 680-95. PMID 23911104 DOI: 10.1016/j.neuron.2013.06.029  1
2013 Lipstein N, Sakaba T, Cooper BH, Lin KH, Strenzke N, Ashery U, Rhee JS, Taschenberger H, Neher E, Brose N. Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling. Neuron. 79: 82-96. PMID 23770256 DOI: 10.1016/j.neuron.2013.05.011  1
2013 Wojcik SM, Tantra M, Stepniak B, Man KN, Müller-Ribbe K, Begemann M, Ju A, Papiol S, Ronnenberg A, Gurvich A, Shin Y, Augustin I, Brose N, Ehrenreich H. Genetic markers of a Munc13 protein family member, BAIAP3, are gender specifically associated with anxiety and benzodiazepine abuse in mice and humans. Molecular Medicine (Cambridge, Mass.). 19: 135-48. PMID 23698091 DOI: 10.2119/molmed.2013.00033  1
2013 Krueger DD, Brose N. Evidence for a common endocannabinoid-related pathomechanism in autism spectrum disorders. Neuron. 78: 408-10. PMID 23664608 DOI: 10.1016/j.neuron.2013.04.030  1
2013 Dolev I, Fogel H, Milshtein H, Berdichevsky Y, Lipstein N, Brose N, Gazit N, Slutsky I. Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change. Nature Neuroscience. 16: 587-95. PMID 23563578 DOI: 10.1038/nn.3376  1
2013 Brose N. Why we need more synaptogenic cell-adhesion proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: 3717-8. PMID 23426626 DOI: 10.1073/pnas.1300505110  1
2013 Nair R, Lauks J, Jung S, Cooke NE, de Wit H, Brose N, Kilimann MW, Verhage M, Rhee J. Neurobeachin regulates neurotransmitter receptor trafficking to synapses. The Journal of Cell Biology. 200: 61-80. PMID 23277425 DOI: 10.1083/jcb.201207113  1
2013 El-Kordi A, Winkler D, Hammerschmidt K, Kästner A, Krueger D, Ronnenberg A, Ritter C, Jatho J, Radyushkin K, Bourgeron T, Fischer J, Brose N, Ehrenreich H. Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism. Behavioural Brain Research. 251: 41-9. PMID 23183221 DOI: 10.1016/j.bbr.2012.11.016  1
2012 Zhao S, Studer D, Chai X, Graber W, Brose N, Nestel S, Young C, Rodriguez EP, Saetzler K, Frotscher M. Structural plasticity of spines at giant mossy fiber synapses. Frontiers in Neural Circuits. 6: 103. PMID 23264762 DOI: 10.3389/fncir.2012.00103  1
2012 Tirard M, Hsiao HH, Nikolov M, Urlaub H, Melchior F, Brose N. In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21122-7. PMID 23213215 DOI: 10.1073/pnas.1215366110  1
2012 Lipstein N, Schaks S, Dimova K, Kalkhof S, Ihling C, Kölbel K, Ashery U, Rhee J, Brose N, Sinz A, Jahn O. Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity. Molecular and Cellular Biology. 32: 4628-41. PMID 22966208 DOI: 10.1128/MCB.00933-12  1
2012 Riccomagno MM, Hurtado A, Wang H, Macopson JG, Griner EM, Betz A, Brose N, Kazanietz MG, Kolodkin AL. The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus. Cell. 149: 1594-606. PMID 22726444 DOI: 10.1016/j.cell.2012.05.018  1
2012 Burgalossi A, Jung S, Man KN, Nair R, Jockusch WJ, Wojcik SM, Brose N, Rhee JS. Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system. Nature Protocols. 7: 1351-65. PMID 22722370 DOI: 10.1038/nprot.2012.074  1
2012 Cooper B, Hemmerlein M, Ammermüller J, Imig C, Reim K, Lipstein N, Kalla S, Kawabe H, Brose N, Brandstätter JH, Varoqueaux F. Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8040-52. PMID 22674279 DOI: 10.1523/JNEUROSCI.4240-11.2012  1
2012 Poulopoulos A, Soykan T, Tuffy LP, Hammer M, Varoqueaux F, Brose N. Homodimerization and isoform-specific heterodimerization of neuroligins. The Biochemical Journal. 446: 321-30. PMID 22671294 DOI: 10.1042/BJ20120808  1
2012 Krueger DD, Tuffy LP, Papadopoulos T, Brose N. The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses. Current Opinion in Neurobiology. 22: 412-22. PMID 22424845 DOI: 10.1016/j.conb.2012.02.012  1
2012 Ivanovic A, Horresh I, Golan N, Spiegel I, Sabanay H, Frechter S, Ohno S, Terada N, Möbius W, Rosenbluth J, Brose N, Peles E. The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves. The Journal of Cell Biology. 196: 337-44. PMID 22291039 DOI: 10.1083/jcb.201111127  1
2012 Zhao S, Studer D, Chai X, Graber W, Brose N, Nestel S, Young C, Rodriguez EP, Saetzler K, Frotscher M. Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing. The Journal of Comparative Neurology. 520: 2340-51. PMID 22237743 DOI: 10.1002/cne.23040  1
2012 Halt AR, Dallapiazza RF, Zhou Y, Stein IS, Qian H, Juntti S, Wojcik S, Brose N, Silva AJ, Hell JW. CaMKII binding to GluN2B is critical during memory consolidation. The Embo Journal. 31: 1203-16. PMID 22234183 DOI: 10.1038/emboj.2011.482  1
2012 Burgalossi A, Jung S, Meyer G, Jockusch W, Jahn O, Taschenberger H, O'Connor V, Nishiki Ti, Takahashi M, Brose N, Rhee JS. SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming Neuron. 73: 620. DOI: 10.1016/j.neuron.2012.01.015  1
2011 Herzog E, Nadrigny F, Silm K, Biesemann C, Helling I, Bersot T, Steffens H, Schwartzmann R, Nägerl UV, El Mestikawy S, Rhee J, Kirchhoff F, Brose N. In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15544-59. PMID 22031900 DOI: 10.1523/JNEUROSCI.2073-11.2011  1
2011 Kawabe H, Brose N. The role of ubiquitylation in nerve cell development. Nature Reviews. Neuroscience. 12: 251-68. PMID 21505515 DOI: 10.1038/nrn3009  1
2011 Reisinger E, Bresee C, Neef J, Nair R, Reuter K, Bulankina A, Nouvian R, Koch M, Bückers J, Kastrup L, Roux I, Petit C, Hell SW, Brose N, Rhee JS, et al. Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4886-95. PMID 21451027 DOI: 10.1523/JNEUROSCI.5122-10.2011  1
2011 Grube S, Gerchen MF, Adamcio B, Pardo LA, Martin S, Malzahn D, Papiol S, Begemann M, Ribbe K, Friedrichs H, Radyushkin KA, Müller M, Benseler F, Riggert J, Falkai P, ... ... Brose N, et al. A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia. Embo Molecular Medicine. 3: 309-19. PMID 21433290 DOI: 10.1002/emmm.201100135  1
2011 Nouvian R, Neef J, Bulankina AV, Reisinger E, PangrÅ¡ič T, Frank T, Sikorra S, Brose N, Binz T, Moser T. Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins. Nature Neuroscience. 14: 411-3. PMID 21378973 DOI: 10.1038/nn.2774  1
2011 Kimura T, Kawabe H, Jiang C, Zhang W, Xiang YY, Lu C, Salter MW, Brose N, Lu WY, Rotin D. Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 3216-21. PMID 21300902 DOI: 10.1073/pnas.1010334108  1
2011 Hoon M, Soykan T, Falkenburger B, Hammer M, Patrizi A, Schmidt KF, Sassoè-Pognetto M, Löwel S, Moser T, Taschenberger H, Brose N, Varoqueaux F. Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina. Proceedings of the National Academy of Sciences of the United States of America. 108: 3053-8. PMID 21282647 DOI: 10.1073/pnas.1006946108  1
2011 Jedlicka P, Hoon M, Papadopoulos T, Vlachos A, Winkels R, Poulopoulos A, Betz H, Deller T, Brose N, Varoqueaux F, Schwarzacher SW. Increased dentate gyrus excitability in neuroligin-2-deficient mice in vivo. Cerebral Cortex (New York, N.Y. : 1991). 21: 357-67. PMID 20530218 DOI: 10.1093/cercor/bhq100  1
2010 Ribbe K, Friedrichs H, Begemann M, Grube S, Papiol S, Kästner A, Gerchen MF, Ackermann V, Tarami A, Treitz A, Flögel M, Adler L, Aldenhoff JB, Becker-Emner M, Becker T, ... ... Brose N, et al. The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients. Bmc Psychiatry. 10: 91. PMID 21067598 DOI: 10.1186/1471-244X-10-91  1
2010 Burgalossi A, Jung S, Meyer G, Jockusch WJ, Jahn O, Taschenberger H, O'Connor VM, Nishiki T, Takahashi M, Brose N, Rhee JS. SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Neuron. 68: 473-87. PMID 21040848 DOI: 10.1016/j.neuron.2010.09.019  1
2010 Liu Y, Schirra C, Edelmann L, Matti U, Rhee J, Hof D, Bruns D, Brose N, Rieger H, Stevens DR, Rettig J. Two distinct secretory vesicle-priming steps in adrenal chromaffin cells. The Journal of Cell Biology. 190: 1067-77. PMID 20855507 DOI: 10.1083/jcb.201001164  1
2010 Begemann M, Grube S, Papiol S, Malzahn D, Krampe H, Ribbe K, Friedrichs H, Radyushkin KA, El-Kordi A, Benseler F, Hannke K, Sperling S, Schwerdtfeger D, Thanhäuser I, Gerchen MF, ... ... Brose N, et al. Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms. Archives of General Psychiatry. 67: 879-88. PMID 20819981 DOI: 10.1001/archgenpsychiatry.2010.107  1
2010 Pangrsic T, Lasarow L, Reuter K, Takago H, Schwander M, Riedel D, Frank T, Tarantino LM, Bailey JS, Strenzke N, Brose N, Müller U, Reisinger E, Moser T. Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells. Nature Neuroscience. 13: 869-76. PMID 20562868 DOI: 10.1038/nn.2578  1
2010 Kawabe H, Brose N. The ubiquitin E3 ligase Nedd4-1 controls neurite development. Cell Cycle (Georgetown, Tex.). 9: 2477-8. PMID 20543564 DOI: 10.4161/cc.9.13.12236  1
2010 Radyushkin K, El-Kordi A, Boretius S, Castaneda S, Ronnenberg A, Reim K, Bickeböller H, Frahm J, Brose N, Ehrenreich H. Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia. Genes, Brain, and Behavior. 9: 592-602. PMID 20412316 DOI: 10.1111/j.1601-183X.2010.00590.x  1
2010 Brose N, O'Connor V, Skehel P. Synaptopathy: dysfunction of synaptic function? Biochemical Society Transactions. 38: 443-4. PMID 20298199 DOI: 10.1042/BST0380443  1
2010 Kawabe H, Neeb A, Dimova K, Young SM, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, ... ... Brose N, et al. Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 65: 358-72. PMID 20159449 DOI: 10.1016/j.neuron.2010.01.007  1
2010 Shin OH, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik SM, Camacho-Perez M, Brose N, Machius M, Rizo J, Rosenmund C, Südhof TC. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nature Structural & Molecular Biology. 17: 280-8. PMID 20154707 DOI: 10.1038/nsmb.1758  1
2010 Groffen AJ, Martens S, Díez Arazola R, Cornelisse LN, Lozovaya N, de Jong AP, Goriounova NA, Habets RL, Takai Y, Borst JG, Brose N, McMahon HT, Verhage M. Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science (New York, N.Y.). 327: 1614-8. PMID 20150444 DOI: 10.1126/science.1183765  1
2010 Fouladkou F, Lu C, Jiang C, Zhou L, She Y, Walls JR, Kawabe H, Brose N, Henkelman RM, Huang A, Bruneau BG, Rotin D. The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1. The Journal of Biological Chemistry. 285: 6770-80. PMID 20026598 DOI: 10.1074/jbc.M109.082347  1
2010 Rodríguez-Castañeda F, Coudevylle N, Becker S, Brose N, Carlomagno T, Griesinger C. 1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex. Biomolecular Nmr Assignments. 4: 45-8. PMID 20013162 DOI: 10.1007/s12104-009-9204-2  1
2010 Rodríguez-Castañeda F, Maestre-Martínez M, Coudevylle N, Dimova K, Junge H, Lipstein N, Lee D, Becker S, Brose N, Jahn O, Carlomagno T, Griesinger C. Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. The Embo Journal. 29: 680-91. PMID 20010694 DOI: 10.1038/emboj.2009.373  1
2010 Breustedt J, Gundlfinger A, Varoqueaux F, Reim K, Brose N, Schmitz D. Munc13-2 differentially affects hippocampal synaptic transmission and plasticity. Cerebral Cortex (New York, N.Y. : 1991). 20: 1109-20. PMID 19700493 DOI: 10.1093/cercor/bhp170  1
2009 Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, ... ... Brose N, et al. Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell. 138: 1222-35. PMID 19766573 DOI: 10.1016/j.cell.2009.06.050  1
2009 Poulopoulos A, Aramuni G, Meyer G, Soykan T, Hoon M, Papadopoulos T, Zhang M, Paarmann I, Fuchs C, Harvey K, Jedlicka P, Schwarzacher SW, Betz H, Harvey RJ, Brose N, et al. Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin. Neuron. 63: 628-42. PMID 19755106 DOI: 10.1016/j.neuron.2009.08.023  1
2009 Brose N, Neher E. Flowers for synaptic endocytosis. Cell. 138: 836-7. PMID 19737513 DOI: 10.1016/j.cell.2009.08.023  1
2009 Wittenmayer N, Körber C, Liu H, Kremer T, Varoqueaux F, Chapman ER, Brose N, Kuner T, Dresbach T. Postsynaptic Neuroligin1 regulates presynaptic maturation. Proceedings of the National Academy of Sciences of the United States of America. 106: 13564-9. PMID 19628693 DOI: 10.1073/pnas.0905819106  1
2009 Siksou L, Varoqueaux F, Pascual O, Triller A, Brose N, Marty S. A common molecular basis for membrane docking and functional priming of synaptic vesicles. The European Journal of Neuroscience. 30: 49-56. PMID 19558619 DOI: 10.1111/j.1460-9568.2009.06811.x  1
2009 Strenzke N, Chanda S, Kopp-Scheinpflug C, Khimich D, Reim K, Bulankina AV, Neef A, Wolf F, Brose N, Xu-Friedman MA, Moser T. Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7991-8004. PMID 19553439 DOI: 10.1523/JNEUROSCI.0632-09.2009  1
2009 Dimova K, Kalkhof S, Pottratz I, Ihling C, Rodriguez-Castaneda F, Liepold T, Griesinger C, Brose N, Sinz A, Jahn O. Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. Biochemistry. 48: 5908-21. PMID 19492809 DOI: 10.1021/bi900300r  1
2009 Reim K, Regus-Leidig H, Ammermüller J, El-Kordi A, Radyushkin K, Ehrenreich H, Brandstätter JH, Brose N. Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4. Journal of Cell Science. 122: 1352-61. PMID 19386896 DOI: 10.1242/jcs.045401  1
2009 Brose N. Synaptogenic proteins and synaptic organizers: "many hands make light work". Neuron. 61: 650-2. PMID 19285459 DOI: 10.1016/j.neuron.2009.02.014  1
2009 Radyushkin K, Hammerschmidt K, Boretius S, Varoqueaux F, El-Kordi A, Ronnenberg A, Winter D, Frahm J, Fischer J, Brose N, Ehrenreich H. Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit. Genes, Brain, and Behavior. 8: 416-25. PMID 19243448 DOI: 10.1111/j.1601-183X.2009.00487.x  1
2009 Wozny C, Breustedt J, Wolk F, Varoqueaux F, Boretius S, Zivkovic AR, Neeb A, Frahm J, Schmitz D, Brose N, Ivanovic A. The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression. Journal of Cell Science. 122: 735-44. PMID 19225127 DOI: 10.1242/jcs.037382  1
2009 Schenck S, Wojcik SM, Brose N, Takamori S. A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles. Nature Neuroscience. 12: 156-62. PMID 19169251 DOI: 10.1038/nn.2248  1
2009 Blundell J, Tabuchi K, Bolliger MF, Blaiss CA, Brose N, Liu X, Südhof TC, Powell CM. Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2. Genes, Brain, and Behavior. 8: 114-26. PMID 19016888 DOI: 10.1111/j.1601-183X.2008.00455.x  1
2009 Brunk I, Blex C, Speidel D, Brose N, Ahnert-Hilger G. Ca2+-dependent activator proteins of secretion promote vesicular monoamine uptake. The Journal of Biological Chemistry. 284: 1050-6. PMID 19008227 DOI: 10.1074/jbc.M805328200  1
2008 Cai H, Reim K, Varoqueaux F, Tapechum S, Hill K, Sørensen JB, Brose N, Chow RH. Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming. Proceedings of the National Academy of Sciences of the United States of America. 105: 19538-43. PMID 19033464 DOI: 10.1073/pnas.0810232105  1
2008 Adamcio B, Sargin D, Stradomska A, Medrihan L, Gertler C, Theis F, Zhang M, Müller M, Hassouna I, Hannke K, Sperling S, Radyushkin K, El-Kordi A, Schulze L, Ronnenberg A, ... ... Brose N, et al. Erythropoietin enhances hippocampal long-term potentiation and memory. Bmc Biology. 6: 37. PMID 18782446 DOI: 10.1186/1741-7007-6-37  1
2008 Patrizi A, Scelfo B, Viltono L, Briatore F, Fukaya M, Watanabe M, Strata P, Varoqueaux F, Brose N, Fritschy JM, Sassoè-Pognetto M. Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America. 105: 13151-6. PMID 18723687 DOI: 10.1073/pnas.0802390105  1
2008 Lou X, Korogod N, Brose N, Schneggenburger R. Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8257-67. PMID 18701688 DOI: 10.1523/JNEUROSCI.0550-08.2008  1
2008 Fouladkou F, Landry T, Kawabe H, Neeb A, Lu C, Brose N, Stambolic V, Rotin D. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proceedings of the National Academy of Sciences of the United States of America. 105: 8585-90. PMID 18562292 DOI: 10.1073/pnas.0803233105  1
2008 Xue M, Stradomska A, Chen H, Brose N, Zhang W, Rosenmund C, Reim K. Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 105: 7875-80. PMID 18505837 DOI: 10.1073/pnas.0803012105  1
2008 Liu Y, Schirra C, Stevens DR, Matti U, Speidel D, Hof D, Bruns D, Brose N, Rettig J. CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5594-601. PMID 18495893 DOI: 10.1523/JNEUROSCI.5672-07.2008  1
2008 Brose N. For better or for worse: complexins regulate SNARE function and vesicle fusion. Traffic (Copenhagen, Denmark). 9: 1403-13. PMID 18445121 DOI: 10.1111/j.1600-0854.2008.00758.x  1
2008 Brose N. Altered complexin expression in psychiatric and neurological disorders: cause or consequence? Molecules and Cells. 25: 7-19. PMID 18319609  1
2008 Zikich D, Mezer A, Varoqueaux F, Sheinin A, Junge HJ, Nachliel E, Melamed R, Brose N, Gutman M, Ashery U. Vesicle priming and recruitment by ubMunc13-2 are differentially regulated by calcium and calmodulin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1949-60. PMID 18287511 DOI: 10.1523/JNEUROSCI.5096-07.2008  1
2008 Jamain S, Radyushkin K, Hammerschmidt K, Granon S, Boretius S, Varoqueaux F, Ramanantsoa N, Gallego J, Ronnenberg A, Winter D, Frahm J, Fischer J, Bourgeron T, Ehrenreich H, Brose N. Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proceedings of the National Academy of Sciences of the United States of America. 105: 1710-5. PMID 18227507 DOI: 10.1073/pnas.0711555105  1
2008 Speidel D, Salehi A, Obermueller S, Lundquist I, Brose N, Renström E, Rorsman P. CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells. Cell Metabolism. 7: 57-67. PMID 18177725 DOI: 10.1016/j.cmet.2007.11.009  1
2007 Jockusch WJ, Speidel D, Sigler A, Sørensen JB, Varoqueaux F, Rhee JS, Brose N. CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell. 131: 796-808. PMID 18022372 DOI: 10.1016/j.cell.2007.11.002  1
2007 Xue M, Reim K, Chen X, Chao HT, Deng H, Rizo J, Brose N, Rosenmund C. Distinct domains of complexin I differentially regulate neurotransmitter release. Nature Structural & Molecular Biology. 14: 949-58. PMID 17828276 DOI: 10.1038/nsmb1292  1
2007 Wegmeyer H, Egea J, Rabe N, Gezelius H, Filosa A, Enjin A, Varoqueaux F, Deininger K, Schnütgen F, Brose N, Klein R, Kullander K, Betz A. EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron. 55: 756-67. PMID 17785182 DOI: 10.1016/j.neuron.2007.07.038  1
2007 Wojcik SM, Brose N. Regulation of membrane fusion in synaptic excitation-secretion coupling: speed and accuracy matter. Neuron. 55: 11-24. PMID 17610814 DOI: 10.1016/j.neuron.2007.06.013  1
2007 Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Südhof TC. Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron. 54: 919-31. PMID 17582332 DOI: 10.1016/j.neuron.2007.05.029  0.72
2007 Glynn D, Reim K, Brose N, Morton AJ. Depletion of Complexin II does not affect disease progression in a mouse model of Huntington's disease (HD); support for role for complexin II in behavioural pathology in a mouse model of HD. Brain Research Bulletin. 72: 108-20. PMID 17352934 DOI: 10.1016/j.brainresbull.2006.10.017  1
2007 Basu J, Betz A, Brose N, Rosenmund C. Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1200-10. PMID 17267576 DOI: 10.1523/JNEUROSCI.4908-06.2007  1
2007 Tordera RM, Totterdell S, Wojcik SM, Brose N, Elizalde N, Lasheras B, Del Rio J. Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1). The European Journal of Neuroscience. 25: 281-90. PMID 17241289 DOI: 10.1111/j.1460-9568.2006.05259.x  1
2007 Brose N. Neurogenetics: Autism - When nerve cells are shy | Neurogenetik: Autismus - Wenn nervenzellen kontaktscheu sind Biospektrum. 13: 614-616.  1
2006 Kalla S, Stern M, Basu J, Varoqueaux F, Reim K, Rosenmund C, Ziv NE, Brose N. Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13054-66. PMID 17167095 DOI: 10.1523/JNEUROSCI.4330-06.2006  1
2006 Dimova K, Kawabe H, Betz A, Brose N, Jahn O. Characterization of the Munc13-calmodulin interaction by photoaffinity labeling. Biochimica Et Biophysica Acta. 1763: 1256-65. PMID 17049382 DOI: 10.1016/j.bbamcr.2006.09.017  1
2006 Varoqueaux F, Aramuni G, Rawson RL, Mohrmann R, Missler M, Gottmann K, Zhang W, Südhof TC, Brose N. Neuroligins determine synapse maturation and function. Neuron. 51: 741-54. PMID 16982420 DOI: 10.1016/j.neuron.2006.09.003  0.72
2006 Herzog E, Takamori S, Jahn R, Brose N, Wojcik SM. Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus. Journal of Neurochemistry. 99: 1011-8. PMID 16942593 DOI: 10.1111/j.1471-4159.2006.04144.x  1
2006 Andrews-Zwilling YS, Kawabe H, Reim K, Varoqueaux F, Brose N. Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. The Journal of Biological Chemistry. 281: 19720-31. PMID 16704978 DOI: 10.1074/jbc.M601421200  1
2006 Wojcik SM, Katsurabayashi S, Guillemin I, Friauf E, Rosenmund C, Brose N, Rhee JS. A shared vesicular carrier allows synaptic corelease of GABA and glycine. Neuron. 50: 575-87. PMID 16701208 DOI: 10.1016/j.neuron.2006.04.016  1
2006 Kang L, He Z, Xu P, Fan J, Betz A, Brose N, Xu T. Munc13-1 is required for the sustained release of insulin from pancreatic beta cells. Cell Metabolism. 3: 463-8. PMID 16697276 DOI: 10.1016/j.cmet.2006.04.012  1
2006 Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY. Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes. 55: 1421-9. PMID 16644700 DOI: 10.2337/db05-1263  1
2006 Vinatier J, Herzog E, Plamont MA, Wojcik SM, Schmidt A, Brose N, Daviet L, El Mestikawy S, Giros B. Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis. Journal of Neurochemistry. 97: 1111-25. PMID 16606361 DOI: 10.1111/j.1471-4159.2006.03821.x  1
2005 Stevens DR, Wu ZX, Matti U, Junge HJ, Schirra C, Becherer U, Wojcik SM, Brose N, Rettig J. Identification of the minimal protein domain required for priming activity of Munc13-1. Current Biology : Cb. 15: 2243-8. PMID 16271475 DOI: 10.1016/j.cub.2005.10.055  1
2005 Gibson HE, Reim K, Brose N, Morton AJ, Jones S. A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse. The European Journal of Neuroscience. 22: 1701-12. PMID 16197510 DOI: 10.1111/j.1460-9568.2005.04349.x  1
2005 Glynn D, Drew CJ, Reim K, Brose N, Morton AJ. Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits. Human Molecular Genetics. 14: 2369-85. PMID 16000319 DOI: 10.1093/hmg/ddi239  1
2005 Varoqueaux F, Sons MS, Plomp JJ, Brose N. Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse. Molecular and Cellular Biology. 25: 5973-84. PMID 15988013 DOI: 10.1128/MCB.25.14.5973-5984.2005  1
2005 Reim K, Wegmeyer H, Brandstätter JH, Xue M, Rosenmund C, Dresbach T, Hofmann K, Brose N. Structurally and functionally unique complexins at retinal ribbon synapses. The Journal of Cell Biology. 169: 669-80. PMID 15911881 DOI: 10.1083/jcb.200502115  1
2005 Speidel D, Bruederle CE, Enk C, Voets T, Varoqueaux F, Reim K, Becherer U, Fornai F, Ruggieri S, Holighaus Y, Weihe E, Bruns D, Brose N, Rettig J. CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron. 46: 75-88. PMID 15820695 DOI: 10.1016/j.neuron.2005.02.019  1
2005 Steinacker P, Schwarz P, Reim K, Brechlin P, Jahn O, Kratzin H, Aitken A, Wiltfang J, Aguzzi A, Bahn E, Baxter HC, Brose N, Otto M. Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Molecular and Cellular Biology. 25: 1339-46. PMID 15684385 DOI: 10.1128/MCB.25.4.1339-1346.2005  1
2005 Neeft M, Wieffer M, de Jong AS, Negroiu G, Metz CH, van Loon A, Griffith J, Krijgsveld J, Wulffraat N, Koch H, Heck AJ, Brose N, Kleijmeer M, van der Sluijs P. Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells. Molecular Biology of the Cell. 16: 731-41. PMID 15548590 DOI: 10.1091/mbc.E04-10-0923  1
2004 Varoqueaux F, Jamain S, Brose N. Neuroligin 2 is exclusively localized to inhibitory synapses. European Journal of Cell Biology. 83: 449-56. PMID 15540461 DOI: 10.1078/0171-9335-00410  1
2004 Dresbach T, Neeb A, Meyer G, Gundelfinger ED, Brose N. Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding. Molecular and Cellular Neurosciences. 27: 227-35. PMID 15519238 DOI: 10.1016/j.mcn.2004.06.013  1
2004 Meyer G, Varoqueaux F, Neeb A, Oschlies M, Brose N. The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin. Neuropharmacology. 47: 724-33. PMID 15458844 DOI: 10.1016/j.neuropharm.2004.06.023  1
2004 Junge HJ, Rhee JS, Jahn O, Varoqueaux F, Spiess J, Waxham MN, Rosenmund C, Brose N. Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity. Cell. 118: 389-401. PMID 15294163 DOI: 10.1016/j.cell.2004.06.029  1
2004 Brose N, Betz A, Wegmeyer H. Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals. Current Opinion in Neurobiology. 14: 328-40. PMID 15194113 DOI: 10.1016/j.conb.2004.05.006  1
2004 Rossner S, Fuchsbrunner K, Lange-Dohna C, Hartlage-Rübsamen M, Bigl V, Betz A, Reim K, Brose N. Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing. The Journal of Biological Chemistry. 279: 27841-4. PMID 15123597 DOI: 10.1074/jbc.C400122200  1
2004 Wojcik SM, Rhee JS, Herzog E, Sigler A, Jahn R, Takamori S, Brose N, Rosenmund C. An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proceedings of the National Academy of Sciences of the United States of America. 101: 7158-63. PMID 15103023 DOI: 10.1073/pnas.0401764101  1
2004 Nagy G, Reim K, Matti U, Brose N, Binz T, Rettig J, Neher E, Sørensen JB. Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron. 41: 417-29. PMID 14766180 DOI: 10.1016/S0896-6273(04)00038-8  1
2003 Meyer G, Brose N. Neuroscience. SPARring with spines. Science (New York, N.Y.). 302: 1341-4. PMID 14631024 DOI: 10.1126/science.1092039  1
2003 Rosenmund C, Rettig J, Brose N. Molecular mechanisms of active zone function. Current Opinion in Neurobiology. 13: 509-19. PMID 14630212 DOI: 10.1016/j.conb.2003.09.011  1
2003 Speidel D, Varoqueaux F, Enk C, Nojiri M, Grishanin RN, Martin TF, Hofmann K, Brose N, Reim K. A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function. The Journal of Biological Chemistry. 278: 52802-9. PMID 14530279 DOI: 10.1074/jbc.M304727200  0.72
2003 Tobaben S, Varoqueaux F, Brose N, Stahl B, Meyer G. A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein. The Journal of Biological Chemistry. 278: 38376-83. PMID 12878599 DOI: 10.1074/jbc.M301558200  1
2003 Sheu L, Pasyk EA, Ji J, Huang X, Gao X, Varoqueaux F, Brose N, Gaisano HY. Regulation of insulin exocytosis by Munc13-1. The Journal of Biological Chemistry. 278: 27556-63. PMID 12871971 DOI: 10.1074/jbc.M303203200  1
2003 Sørensen JB, Nagy G, Varoqueaux F, Nehring RB, Brose N, Wilson MC, Neher E. Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23. Cell. 114: 75-86. PMID 12859899 DOI: 10.1016/S0092-8674(03)00477-X  1
2002 Brose N, Neher E. Specificity emerges in the dissection of diacylglycerol- and protein kinase C-mediated signalling pathways. Proceedings of the National Academy of Sciences of the United States of America. 99: 16522-3. PMID 12486246 DOI: 10.1073/pnas.022708199  1
2002 Brose N, Rosenmund C. Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. Journal of Cell Science. 115: 4399-411. PMID 12414987 DOI: 10.1242/jcs.00122  1
2002 Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proceedings of the National Academy of Sciences of the United States of America. 99: 9037-42. PMID 12070347 DOI: 10.1073/pnas.122623799  1
2002 Antonin W, Wagner M, Riedel D, Brose N, Jahn R. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion. Molecular and Cellular Biology. 22: 1545-54. PMID 11839820 DOI: 10.1128/MCB.22.5.1545-1554.2002  1
2002 Rosenmund C, Sigler A, Augustin I, Reim K, Brose N, Rhee JS. Differential control of vesicle priming and short-term plasticity by Munc13 isoforms. Neuron. 33: 411-24. PMID 11832228 DOI: 10.1016/S0896-6273(02)00568-8  1
2002 Rhee JS, Betz A, Pyott S, Reim K, Varoqueaux F, Augustin I, Hesse D, Südhof TC, Takahashi M, Rosenmund C, Brose N. Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs. Cell. 108: 121-33. PMID 11792326  1
2001 Betz A, Thakur P, Junge HJ, Ashery U, Rhee JS, Scheuss V, Rosenmund C, Rettig J, Brose N. Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming. Neuron. 30: 183-96. PMID 11343654 DOI: 10.1016/S0896-6273(01)00272-0  1
2001 Schmitz F, Augustin I, Brose N. The synaptic vesicle priming protein Munc13-1 is absent from tonically active ribbon synapses of the rat retina. Brain Research. 895: 258-63. PMID 11259787 DOI: 10.1016/S0006-8993(01)02078-9  1
2001 Fernández-Chacón R, Königstorfer A, Gerber SH, García J, Matos MF, Stevens CF, Brose N, Rizo J, Rosenmund C, Südhof TC. Synaptotagmin I functions as a calcium regulator of release probability. Nature. 410: 41-9. PMID 11242035 DOI: 10.1038/35065004  1
2001 Reim K, Mansour M, Varoqueaux F, McMahon HT, Südhof TC, Brose N, Rosenmund C. Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell. 104: 71-81. PMID 11163241 DOI: 10.1016/S0092-8674(01)00192-1  1
2001 Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW, Brose N. The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 10-7. PMID 11150314  1
2000 Ashery U, Varoqueaux F, Voets T, Betz A, Thakur P, Koch H, Neher E, Brose N, Rettig J. Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells. The Embo Journal. 19: 3586-96. PMID 10899113 DOI: 10.1093/emboj/19.14.3586  1
2000 Koch H, Hofmann K, Brose N. Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform. The Biochemical Journal. 349: 247-53. PMID 10861235 DOI: 10.1042/0264-6021:3490247  1
2000 Brose N, Rosenmund C, Rettig J. Regulation of transmitter release by Unc-13 and its homologues. Current Opinion in Neurobiology. 10: 303-11. PMID 10851170 DOI: 10.1016/S0959-4388(00)00105-7  1
1999 Brose N, Rosenmund C. SV2: SVeeping up excess Ca2+ or tranSVorming presynaptic Ca2+ sensors? Neuron. 24: 766-8. PMID 10624939  1
1999 Brose N. Synaptic cell adhesion proteins and synaptogenesis in the mammalian central nervous system. Die Naturwissenschaften. 86: 516-24. PMID 10551945 DOI: 10.1007/s001140050666  1
1999 Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N, Kretzschmar H. Evidence of presynaptic location and function of the prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8866-75. PMID 10516306  1
1999 Neeb A, Koch H, Schürmann A, Brose N. Direct interaction between the ARF-specific guanine nucleotide exchange factor msec7-1 and presynaptic Munc13-1. European Journal of Cell Biology. 78: 533-8. PMID 10494859 DOI: 10.1016/S0171-9335(99)80018-1  1
1999 Ashery U, Betz A, Xu T, Brose N, Rettig J. An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system. European Journal of Cell Biology. 78: 525-32. PMID 10494858  1
1999 Duncan RR, Betz A, Shipston MJ, Brose N, Chow RH. Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo. The Journal of Biological Chemistry. 274: 27347-50. PMID 10488064 DOI: 10.1074/jbc.274.39.27347  1
1999 Augustin I, Rosenmund C, Südhof TC, Brose N. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature. 400: 457-61. PMID 10440375 DOI: 10.1038/22768  1
1999 Song JY, Ichtchenko K, Südhof TC, Brose N. Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proceedings of the National Academy of Sciences of the United States of America. 96: 1100-5. PMID 9927700 DOI: 10.1073/pnas.96.3.1100  1
1999 Ashery U, Koch H, Scheuss V, Brose N, Rettig J. A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1. Proceedings of the National Academy of Sciences of the United States of America. 96: 1094-9. PMID 9927699 DOI: 10.1073/pnas.96.3.1094  1
1999 Augustin I, Betz A, Herrmann C, Jo T, Brose N. Differential expression of two novel Munc13 proteins in rat brain. The Biochemical Journal. 337: 363-71. PMID 9895278 DOI: 10.1042/0264-6021:3370363  1
1998 Betz A, Ashery U, Rickmann M, Augustin I, Neher E, Südhof TC, Rettig J, Brose N. Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron. 21: 123-36. PMID 9697857 DOI: 10.1016/S0896-6273(00)80520-6  1
1997 Telemenakis I, Benseler F, Stenius K, Südhof TC, Brose N. Rat homologues of yeast sec7p. European Journal of Cell Biology. 74: 143-9. PMID 9352219  1
1997 Betz A, Okamoto M, Benseler F, Brose N. Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin. The Journal of Biological Chemistry. 272: 2520-6. PMID 8999968 DOI: 10.1074/jbc.272.4.2520  1
1996 Betz A, Telemenakis I, Hofmann K, Brose N. Mammalian Unc-13 homologues as possible regulators of neurotransmitter release. Biochemical Society Transactions. 24: 661-6. PMID 8878822  1
1996 Chapman ER, Blasi J, An S, Brose N, Johnston PA, Südhof TC, Jahn R. Fatty acylation of synaptotagmin in PC12 cells and synaptosomes. Biochemical and Biophysical Research Communications. 225: 326-32. PMID 8769138 DOI: 10.1006/bbrc.1996.1174  1
1995 Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC. Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Nature. 375: 594-9. PMID 7791877 DOI: 10.1038/375594a0  1
1995 Brose N, Hofmann K, Hata Y, Südhof TC. Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. The Journal of Biological Chemistry. 270: 25273-80. PMID 7559667 DOI: 10.1074/jbc.270.42.25273  1
1994 Siegel SJ, Brose N, Janssen WG, Gasic GP, Jahn R, Heinemann SF, Morrison JH. Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 91: 564-8. PMID 8290563  1
1994 Huntley GW, Vickers JC, Janssen W, Brose N, Heinemann SF, Morrison JH. Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3603-19. PMID 8207475  1
1994 Brose N, Huntley GW, Stern-Bach Y, Sharma G, Morrison JH, Heinemann SF. Differential assembly of coexpressed glutamate receptor subunits in neurons of rat cerebral cortex. The Journal of Biological Chemistry. 269: 16780-4. PMID 8207001  1
1994 Trevisan L, Fitzgerald LW, Brose N, Gasic GP, Heinemann SF, Duman RS, Nestler EJ. Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. Journal of Neurochemistry. 62: 1635-8. PMID 8133290  1
1994 Böckers TM, Zimmer M, Müller A, Bergmann M, Brose N, Kreutz MR. Expression of the NMDA R1 receptor in selected human brain regions. Neuroreport. 5: 965-9. PMID 8061305  1
1994 Spiro JE, Brose N, Heinemann SF, Heiligenberg W. Immunolocalization of NMDA receptors in the central nervous system of weakly electric fish: functional implications for the modulation of a neuronal oscillator. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6289-99. PMID 7931581  1
1994 Puchalski RB, Louis JC, Brose N, Traynelis SF, Egebjerg J, Kukekov V, Wenthold RJ, Rogers SW, Lin F, Moran T. Selective RNA editing and subunit assembly of native glutamate receptors. Neuron. 13: 131-47. PMID 7519023 DOI: 10.1016/0896-6273(94)90464-2  1
1993 Brose N. Membrane fusion takes excitatory turn: syntaxin, vesicle docking protein, or glutamate receptor? Cell. 75: 1043-4. PMID 8261506 DOI: 10.1016/0092-8674(93)90313-F  1
1993 Brose N, Gasic GP, Vetter DE, Sullivan JM, Heinemann SF. Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1. The Journal of Biological Chemistry. 268: 22663-71. PMID 8226775  1
1993 Sucher NJ, Brose N, Deitcher DL, Awobuluyi M, Gasic GP, Bading H, Cepko CL, Greenberg ME, Jahn R, Heinemann SF. Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells. The Journal of Biological Chemistry. 268: 22299-304. PMID 8226739  1
1992 Brose N, Petrenko AG, Südhof TC, Jahn R. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science (New York, N.Y.). 256: 1021-5. PMID 1589771  1
1991 Perin MS, Brose N, Jahn R, Südhof TC. Domain structure of synaptotagmin (p65) The Journal of Biological Chemistry. 266: 623-9. PMID 1985919  1
1990 Brose N, Thomas A, Weber MG, Jahn R. A chloride- and calcium-dependent glutamate-binding protein from rat brain. Identification as a ubiquitous constituent of the inner mitochondrial membrane. The Journal of Biological Chemistry. 265: 10604-10. PMID 2162355  1
1989 Brose N, O'Neill RD, Boutelle MG, Fillenz M. The effects of anxiolytic and anxiogenic benzodiazepine receptor ligands on motor activity and levels of ascorbic acid in the nucleus accumbens and striatum of the rat. Neuropharmacology. 28: 509-14. PMID 2566950 DOI: 10.1016/0028-3908(89)90087-7  1
1989 Brose N, Halpain S, Suchanek C, Jahn R. Characterization and partial purification of a chloride- and calcium-dependent glutamate-binding protein from rat brain. The Journal of Biological Chemistry. 264: 9619-25. PMID 2566612  1
1988 Brose N, O'Neill RD, Boutelle MG, Fillenz M. Dopamine in the basal ganglia and benzodiazepine-induced sedation. Neuropharmacology. 27: 589-95. PMID 3419542 DOI: 10.1016/0028-3908(88)90179-7  1
1987 Brose N, O'Neill RD, Boutelle MG, Anderson SM, Fillenz M. Effects of an anxiogenic benzodiazepine receptor ligand on motor activity and dopamine release in nucleus accumbens and striatum in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 2917-26. PMID 3040928  1
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