Year |
Citation |
Score |
2024 |
Dinkel L, Hummel S, Zenatti V, Malara M, Tillmann Y, Colombo A, Monasor LS, Suh JH, Logan T, Roth S, Paeger L, Hoffelner P, Bludau O, Schmidt A, Müller SA, ... ... Herms J, et al. Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease. Science Translational Medicine. 16: eadl4616. PMID 39630885 DOI: 10.1126/scitranslmed.adl4616 |
0.512 |
|
2024 |
Slemann L, Gnörich J, Hummel S, Bartos LM, Klaus C, Kling A, Kusche-Palenga J, Kunte ST, Kunze LH, Englert AL, Li Y, Vogler L, Katzdobler S, Palleis C, Bernhardt A, ... ... Herms J, et al. Neuronal and oligodendroglial, but not astroglial, tau translates to in vivo tau PET signals in individuals with primary tauopathies. Acta Neuropathologica. 148: 70. PMID 39580770 DOI: 10.1007/s00401-024-02834-7 |
0.565 |
|
2024 |
Zatcepin A, Gnörich J, Rauchmann BS, Bartos LM, Wagner S, Franzmeier N, Malpetti M, Xiang X, Shi Y, Parhizkar S, Grosch M, Wind-Mark K, Kunte ST, Beyer L, Meyer C, ... ... Herms J, et al. Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease. Molecular Neurodegeneration. 19: 64. PMID 39238030 DOI: 10.1186/s13024-024-00752-6 |
0.515 |
|
2024 |
Bartos LM, Quach S, Zenatti V, Kirchleitner SV, Blobner J, Wind-Mark K, Kolabas ZI, Ulukaya S, Holzgreve A, Ruf VC, Kunze LH, Kunte ST, Hoermann L, Härtel M, Park HE, ... ... Herms J, et al. Remote Neuroinflammation in Newly Diagnosed Glioblastoma Correlates with Unfavorable Clinical Outcome. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 39150564 DOI: 10.1158/1078-0432.CCR-24-1563 |
0.444 |
|
2024 |
Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, ... ... Herms J, et al. Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. PMID 39143410 DOI: 10.1038/s41593-024-01752-x |
0.478 |
|
2024 |
Gnörich J, Koehler M, Wind-Mark K, Klaus C, Zatcepin A, Palumbo G, Lalia M, Monasor LS, Beyer L, Eckenweber F, Scheifele M, Gildehaus FJ, von Ungern-Sternberg B, Barthel H, Sabri O, ... ... Herms J, et al. Towards multicenter β-amyloid PET imaging in mouse models: A triple scanner head-to-head comparison. Neuroimage. 297: 120748. PMID 39069223 DOI: 10.1016/j.neuroimage.2024.120748 |
0.556 |
|
2024 |
Ruch F, Gnörich J, Wind K, Köhler M, Zatcepin A, Wiedemann T, Gildehaus FJ, Lindner S, Boening G, von Ungern-Sternberg B, Beyer L, Herms J, Bartenstein P, Brendel M, Eckenweber F. Validity and value of metabolic connectivity in mouse models of β-amyloid and tauopathy. Neuroimage. 286: 120513. PMID 38191101 DOI: 10.1016/j.neuroimage.2024.120513 |
0.565 |
|
2023 |
Bartos LM, Kirchleitner SV, Kolabas ZI, Quach S, Beck A, Lorenz J, Blobner J, Mueller SA, Ulukaya S, Hoeher L, Horvath I, Wind-Mark K, Holzgreve A, Ruf VC, Gold L, ... ... Herms J, et al. Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution. Science Advances. 9: eadi8986. PMID 37889970 DOI: 10.1126/sciadv.adi8986 |
0.5 |
|
2023 |
Weidner L, Lorenz J, Quach S, Braun FK, Rothhammer-Hampl T, Ammer LM, Vollmann-Zwerenz A, Bartos LM, Dekorsy FJ, Holzgreve A, Kirchleitner SV, Thon N, Greve T, Ruf V, Herms J, et al. Translocator protein (18kDA) (TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages. Acta Neuropathologica Communications. 11: 147. PMID 37697350 DOI: 10.1186/s40478-023-01651-5 |
0.502 |
|
2023 |
Vogler L, Ballweg A, Bohr B, Briel N, Wind K, Antons M, Kunze LH, Gnörich J, Lindner S, Gildehaus FJ, Baumann K, Bartenstein P, Boening G, Ziegler SI, Levin J, ... ... Herms J, et al. Assessment of synaptic loss in mouse models of β-amyloid and tau pathology using [F]UCB-H PET imaging. Neuroimage. Clinical. 39: 103484. PMID 37541098 DOI: 10.1016/j.nicl.2023.103484 |
0.577 |
|
2023 |
Albert NL, Nelwan DV, Fleischmann DF, Quach S, von Rohr K, Kaiser L, Teske N, Unterrainer LM, Bartos LM, Ruf VC, Brendel M, Riemenschneider MJ, Wetzel C, Herms J, Rupprecht R, et al. Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 37536737 DOI: 10.2967/jnumed.122.265247 |
0.511 |
|
2023 |
Kunze LH, Ruch F, Biechele G, Eckenweber F, Wind-Mark K, Dinkel L, Feyen P, Bartenstein P, Ziegler S, Paeger L, Tahirovic S, Herms J, Brendel M. Long-Term Pioglitazone Treatment Has No Significant Impact on Microglial Activation and Tau Pathology in P301S Mice. International Journal of Molecular Sciences. 24. PMID 37373253 DOI: 10.3390/ijms241210106 |
0.56 |
|
2023 |
Koeglsperger T, Rumpf SL, Schließer P, Struebing FL, Brendel M, Levin J, Trenkwalder C, Höglinger GU, Herms J. Neuropathology of incidental Lewy body & prodromal Parkinson's disease. Molecular Neurodegeneration. 18: 32. PMID 37173733 DOI: 10.1186/s13024-023-00622-7 |
0.458 |
|
2023 |
Ballweg A, Klaus C, Vogler L, Katzdobler S, Wind K, Zatcepin A, Ziegler SI, Secgin B, Eckenweber F, Bohr B, Bernhardt A, Fietzek U, Rauchmann BS, Stoecklein S, Quach S, ... ... Herms J, et al. [F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data. Journal of Neuroinflammation. 20: 68. PMID 36906584 DOI: 10.1186/s12974-023-02749-2 |
0.57 |
|
2023 |
Gnörich J, Reifschneider A, Wind K, Zatcepin A, Kunte ST, Beumers P, Bartos LM, Wiedemann T, Grosch M, Xiang X, Fard MK, Ruch F, Werner G, Koehler M, Slemann L, ... ... Herms J, et al. Depletion and activation of microglia impact metabolic connectivity of the mouse brain. Journal of Neuroinflammation. 20: 47. PMID 36829182 DOI: 10.1186/s12974-023-02735-8 |
0.483 |
|
2022 |
Quach S, Holzgreve A, Kaiser L, Unterrainer M, Dekorsy FJ, Nelwan DV, Bartos LM, Kirchleitner SV, Weller J, Weidner L, Niyazi M, Ruf VC, Herms J, Stöcklein S, Wetzel C, et al. TSPO PET signal using [F]GE180 is associated with survival in recurrent gliomas. European Journal of Nuclear Medicine and Molecular Imaging. PMID 36329288 DOI: 10.1007/s00259-022-06006-1 |
0.502 |
|
2022 |
Blume T, Filser S, Sgobio C, Peters F, Neumann U, Shimshek D, Saito T, Saido TC, Brendel M, Herms J. β-secretase inhibition prevents structural spine plasticity deficits in mice. Frontiers in Aging Neuroscience. 14: 909586. PMID 35936777 DOI: 10.3389/fnagi.2022.909586 |
0.532 |
|
2022 |
Blume T, Deussing M, Biechele G, Peters F, Zott B, Schmidt C, Franzmeier N, Wind K, Eckenweber F, Sacher C, Shi Y, Ochs K, Kleinberger G, Xiang X, Focke C, ... ... Herms J, et al. Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition. Frontiers in Aging Neuroscience. 14: 854031. PMID 35431893 DOI: 10.3389/fnagi.2022.854031 |
0.58 |
|
2022 |
Messerschmidt K, Barthel H, Brendel M, Scherlach C, Hoffmann KT, Rauchmann BS, Rullmann M, Marek K, Villemagne VL, Rumpf JJ, Saur D, Schroeter ML, Schildan A, Patt M, Beyer L, ... ... Herms J, et al. F-PI-2620 Tau PET Improves the Imaging Diagnosis of Progressive Supranuclear Palsy. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35422444 DOI: 10.2967/jnumed.121.262854 |
0.542 |
|
2022 |
Franzmeier N, Brendel M, Beyer L, Slemann L, Kovacs GG, Arzberger T, Kurz C, Respondek G, Lukic MJ, Biel D, Rubinski A, Frontzkowski L, Hummel S, Müller A, Finze A, ... ... Herms J, et al. Tau deposition patterns are associated with functional connectivity in primary tauopathies. Nature Communications. 13: 1362. PMID 35292638 DOI: 10.1038/s41467-022-28896-3 |
0.535 |
|
2022 |
Shi Y, Cui M, Ochs K, Brendel M, Strübing FL, Briel N, Eckenweber F, Zou C, Banati RB, Liu GJ, Middleton RJ, Rupprecht R, Rudolph U, Zeilhofer HU, Rammes G, ... Herms J, et al. Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO). Nature Neuroscience. 25: 317-329. PMID 35228700 DOI: 10.1038/s41593-022-01013-9 |
0.452 |
|
2021 |
Xiang X, Wind K, Wiedemann T, Blume T, Shi Y, Briel N, Beyer L, Biechele G, Eckenweber F, Zatcepin A, Lammich S, Ribicic S, Tahirovic S, Willem M, Deussing M, ... ... Herms J, et al. Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. Science Translational Medicine. 13: eabe5640. PMID 34644146 DOI: 10.1126/scitranslmed.abe5640 |
0.5 |
|
2021 |
Biechele G, Blume T, Deussing M, Zott B, Shi Y, Xiang X, Franzmeier N, Kleinberger G, Peters F, Ochs K, Focke C, Sacher C, Wind K, Schmidt C, Lindner S, ... ... Herms J, et al. Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation. Theranostics. 11: 8964-8976. PMID 34522221 DOI: 10.7150/thno.64022 |
0.569 |
|
2021 |
Willroider M, Roeber S, Horn AKE, Arzberger T, Scheifele M, Respondek G, Sabri O, Barthel H, Patt M, Mishchenko O, Schildan A, Mueller A, Koglin N, Stephens A, Levin J, ... ... Herms J, et al. Superiority of Formalin-Fixed Paraffin-Embedded Brain Tissue for Assessment of Progressive Supranuclear Palsy Tau Pathology With [ F]PI-2620. Frontiers in Neurology. 12: 684523. PMID 34276540 DOI: 10.3389/fneur.2021.684523 |
0.528 |
|
2021 |
Mittlmeier LM, Suchorska B, Ruf V, Holzgreve A, Brendel M, Herms J, Bartenstein P, Tonn JC, Unterrainer M, Albert NL. F-FET PET Uptake Characteristics of Long-Term IDH-Wildtype Diffuse Glioma Survivors. Cancers. 13. PMID 34202726 DOI: 10.3390/cancers13133163 |
0.502 |
|
2021 |
Song M, Beyer L, Kaiser L, Barthel H, van Eimeren T, Marek K, Nitschmann A, Scheifele M, Palleis C, Respondek G, Kern M, Biechele G, Hammes J, Bischof G, Barbe M, ... ... Herms J, et al. Binding characteristics of [F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211018904. PMID 34044665 DOI: 10.1177/0271678X211018904 |
0.467 |
|
2021 |
Biechele G, Sebastian Monasor L, Wind K, Blume T, Parhizkar S, Arzberger T, Sacher C, Beyer L, Eckenweber F, Gildehaus FJ, von Ungern-Sternberg B, Willem M, Bartenstein P, Cumming P, Rominger A, ... Herms J, et al. Glitter in the Darkness? Non-fibrillar β-amyloid Plaque Components Significantly Impact the β-amyloid PET Signal in Mouse Models of Alzheimer's Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 34016733 DOI: 10.2967/jnumed.120.261858 |
0.592 |
|
2021 |
Unterrainer M, Ruf V, von Rohr K, Suchorska B, Mittlmeier LM, Beyer L, Brendel M, Wenter V, Kunz WG, Bartenstein P, Herms J, Niyazi M, Tonn JC, Albert NL. TERT-Promoter Mutational Status in Glioblastoma - Is There an Association With Amino Acid Uptake on Dynamic F-FET PET? Frontiers in Oncology. 11: 645316. PMID 33996563 DOI: 10.3389/fonc.2021.645316 |
0.504 |
|
2020 |
Biechele G, Wind K, Blume T, Sacher C, Beyer L, Eckenweber F, Franzmeier N, Ewers M, Zott B, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Tahirovic S, Willem M, Bartenstein P, ... ... Herms J, et al. Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in App mice. Neuroimage. 117707. PMID 33385560 DOI: 10.1016/j.neuroimage.2020.117707 |
0.556 |
|
2020 |
Biechele G, Franzmeier N, Blume T, Ewers M, Luque JM, Eckenweber F, Sacher C, Beyer L, Ruch-Rubinstein F, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Cumming P, Bartenstein P, Rominger A, ... ... Herms J, et al. Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases. Journal of Neuroinflammation. 17: 374. PMID 33317543 DOI: 10.1186/s12974-020-02046-2 |
0.546 |
|
2020 |
Palleis C, Sauerbeck J, Beyer L, Harris S, Schmitt J, Morenas-Rodriguez E, Finze A, Nitschmann A, Ruch-Rubinstein F, Eckenweber F, Biechele G, Blume T, Shi Y, Weidinger E, Prix C, ... ... Herms J, et al. In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33245166 DOI: 10.1002/mds.28395 |
0.446 |
|
2020 |
Brendel M, Barthel H, van Eimeren T, Marek K, Beyer L, Song M, Palleis C, Gehmeyr M, Fietzek U, Respondek G, Sauerbeck J, Nitschmann A, Zach C, Hammes J, Barbe MT, ... ... Herms J, et al. Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy. Jama Neurology. 77: 1408-1419. PMID 33165511 DOI: 10.1001/Jamaneurol.2020.2526 |
0.549 |
|
2020 |
Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M, et al. Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation. Embo Molecular Medicine. e12308. PMID 32790063 DOI: 10.15252/Emmm.202012308 |
0.626 |
|
2020 |
Eckenweber F, Medina-Luque J, Blume T, Sacher C, Biechele G, Wind K, Deussing M, Briel N, Lindner S, Boening G, von Ungern-Sternberg B, Unterrainer M, Albert NL, Zwergal A, Levin J, ... ... Herms J, et al. Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning. Journal of Neuroinflammation. 17: 208. PMID 32660586 DOI: 10.1186/S12974-020-01883-5 |
0.595 |
|
2020 |
Sebastian Monasor L, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J, Willem M, Haass C, et al. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. Elife. 9. PMID 32510331 DOI: 10.7554/Elife.54083 |
0.408 |
|
2020 |
Sacher C, Blume T, Beyer L, Biechele G, Sauerbeck J, Eckenweber F, Deussing M, Focke C, Parhizkar S, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Baumann K, Tahirovic S, Kleinberger G, ... ... Herms J, et al. Asymmetry of fibrillar plaque burden in amyloid mouse models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32414948 DOI: 10.2967/Jnumed.120.242750 |
0.626 |
|
2020 |
Beyer L, Nitschmann A, Barthel H, van Eimeren T, Unterrainer M, Sauerbeck J, Marek K, Song M, Palleis C, Respondek G, Hammes J, Barbe MT, Onur Ö, Jessen F, Saur D, ... ... Herms J, et al. Early-phase [F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32318783 DOI: 10.1007/S00259-020-04788-W |
0.598 |
|
2020 |
Monasor LS, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J, Willem M, Haass C, et al. Author response: Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models Elife. DOI: 10.7554/Elife.54083.Sa2 |
0.359 |
|
2019 |
Peters F, Salihoglu H, Pratsch K, Herzog E, Pigoni M, Sgobio C, Lichtenthaler SF, Neumann U, Herms J. Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease. The Embo Journal. e2019102345. PMID 31701556 DOI: 10.15252/Embj.2019102345 |
0.399 |
|
2019 |
Unterrainer M, Ruf V, Cyran CC, Brendel M, Thon N, Herms J, Schüller U, Tonn JC, Bartenstein P, Albert NL. Identification of Distant Metastases From Recurrent Gliosarcoma Using Whole-Body 18F-FDG PET/CT. Clinical Nuclear Medicine. 44: 923-924. PMID 31584491 DOI: 10.1097/Rlu.0000000000002790 |
0.561 |
|
2019 |
Unterrainer M, Fleischmann DF, Vettermann F, Ruf V, Kaiser L, Nelwan D, Lindner S, Brendel M, Wenter V, Stöcklein S, Herms J, Milenkovic VM, Rupprecht R, Tonn JC, Belka C, et al. TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative F-GE-180 PET study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31486876 DOI: 10.1007/S00259-019-04491-5 |
0.575 |
|
2019 |
Blumenstock S, Angelo MF, Peters F, Dorostkar MM, Ruf VC, Luckner M, Crux S, Slapakova L, Arzberger T, Claverol S, Herzog E, Herms J. Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy. Acta Neuropathologica. PMID 31451907 DOI: 10.1007/S00401-019-02063-3 |
0.333 |
|
2019 |
Vettermann F, Suchorska B, Unterrainer M, Nelwan D, Forbrig R, Ruf V, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC, Albert NL. Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic F-FET PET. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31410540 DOI: 10.1007/S00259-019-04477-3 |
0.336 |
|
2019 |
Brendel M, Deussing M, Blume T, Kaiser L, Probst F, Overhoff F, Peters F, von Ungern-Sternberg B, Ryazanov S, Leonov A, Griesinger C, Zwergal A, Levin J, Bartenstein P, Yakushev I, ... ... Herms J, et al. Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research & Therapy. 11: 67. PMID 31370885 DOI: 10.1186/S13195-019-0522-Z |
0.626 |
|
2019 |
Sacher C, Blume T, Beyer L, Peters F, Eckenweber F, Sgobio C, Deussing M, Albert NL, Unterrainer M, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Brzak I, Neumann U, Saito T, ... ... Herms J, et al. Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second Generation Amyloid-beta Mouse Model. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31302633 DOI: 10.2967/Jnumed.119.227322 |
0.618 |
|
2019 |
Marinković P, Blumenstock S, Goltstein PM, Korzhova V, Peters F, Knebl A, Herms J. In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model. Brain : a Journal of Neurology. PMID 30847469 DOI: 10.1093/Brain/Awz035 |
0.371 |
|
2019 |
Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, ... ... Herms J, et al. ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine. PMID 30692699 DOI: 10.1038/S41591-018-0336-8 |
0.352 |
|
2019 |
Montagna E, Crux S, Luckner M, Herber J, Colombo AV, Marinković P, Tahirovic S, Lichtenthaler SF, Wanner G, Müller UC, Sgobio C, Herms J. In vivo Ca imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. Glia. PMID 30667091 DOI: 10.1002/Glia.23584 |
0.32 |
|
2019 |
Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, ... ... Herms J, et al. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. PMID 30617257 DOI: 10.1038/S41593-018-0296-9 |
0.58 |
|
2019 |
Brendel M, Barthel H, Eimeren Tv, Marek K, Beyer L, Song M, Palleis C, Respondek G, Sauerbeck J, Hammes J, Barbe M, Onur OA, Jessen F, Saur D, Schroeter ML, ... ... Herms J, et al. Ic-P-161: 18F-Pi2620 Tau-Pet In Progressive Supranuclear Palsy: A Multi-Center Evaluation Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2783 |
0.558 |
|
2018 |
Brendel M, Jaworska A, Overhoff F, Blume T, Probst F, Gildehaus FJ, Bartenstein P, Haass C, Bohrmann B, Herms J, Willem M, Rominger A. Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation. Theranostics. 8: 4957-4968. PMID 30429879 DOI: 10.7150/Thno.27868 |
0.627 |
|
2018 |
Blume T, Focke C, Peters F, Deussing M, Albert NL, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Ozmen L, Baumann K, Bartenstein P, Rominger A, Herms J, Brendel M. Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. Journal of Neuroinflammation. 15: 307. PMID 30400912 DOI: 10.1186/S12974-018-1347-6 |
0.605 |
|
2018 |
Focke C, Blume T, Zott B, Yuan Shi Y, Deussing M, Peters F, Schmidt C, Kleinberger G, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Ozmen L, Baumann K, ... ... Herms J, et al. Early and longitudinal microglial activation but not amyloid accumulation predict cognitive outcome in PS2APP mice. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30262517 DOI: 10.2967/Jnumed.118.217703 |
0.584 |
|
2018 |
Unterrainer M, Fleischmann DF, Diekmann C, Vomacka L, Lindner S, Vettermann F, Brendel M, Wenter V, Ertl-Wagner B, Herms J, Wetzel C, Rupprecht R, Tonn JC, Belka C, Bartenstein P, et al. Comparison of F-GE-180 and dynamic F-FET PET in high grade glioma: a double-tracer pilot study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30244386 DOI: 10.1007/S00259-018-4166-1 |
0.572 |
|
2018 |
Xiang X, Piers TM, Wefers B, Zhu K, Mallach A, Brunner B, Kleinberger G, Song W, Colonna M, Herms J, Wurst W, Pocock JM, Haass C. The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. Molecular Neurodegeneration. 13: 49. PMID 30185230 DOI: 10.1186/S13024-018-0280-6 |
0.345 |
|
2018 |
Blume T, Filser S, Jaworska A, Blain JF, Koenig G, Moschke K, Lichtenthaler SF, Herms J. BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines. Frontiers in Aging Neuroscience. 10: 229. PMID 30093858 DOI: 10.3389/Fnagi.2018.00229 |
0.375 |
|
2018 |
Rammes G, Seeser F, Mattusch K, Zhu K, Haas L, Kummer M, Heneka M, Herms J, Parsons CG. The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP). Neuropharmacology. PMID 30016667 DOI: 10.1016/J.Neuropharm.2018.07.021 |
0.35 |
|
2018 |
Zhu K, Peters F, Filser S, Herms J. Consequences of Pharmacological BACE Inhibition on Synaptic Structure and Function. Biological Psychiatry. PMID 29945719 DOI: 10.1016/J.Biopsych.2018.04.022 |
0.387 |
|
2018 |
Crux S, Herms J, Dorostkar MM. Tcf4 regulates dendritic spine density and morphology in the adult brain. Plos One. 13: e0199359. PMID 29933371 DOI: 10.1371/Journal.Pone.0199359 |
0.319 |
|
2018 |
Brendel M, Yousefi BH, Blume T, Herz M, Focke C, Deussing M, Peters F, Lindner S, von Ungern-Sternberg B, Drzezga A, Bartenstein P, Haass C, Okamura N, Herms J, Yakushev I, et al. Comparison of F-T807 and F-THK5117 PET in a Mouse Model of Tau Pathology. Frontiers in Aging Neuroscience. 10: 174. PMID 29930508 DOI: 10.3389/Fnagi.2018.00174 |
0.615 |
|
2018 |
Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, et al. Data on specificity of [F]GE180 uptake for TSPO expression in rodent brain and myocardium. Data in Brief. 19: 331-336. PMID 29892655 DOI: 10.1016/J.Dib.2018.04.133 |
0.562 |
|
2018 |
Unterrrainer M, Winkelmann I, Suchorska B, Giese A, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC, Albert NL. Biological tumour volumes of gliomas in early and standard 20-40 minF-FET PET images differ according to IDH mutation status. European Journal of Nuclear Medicine and Molecular Imaging. PMID 29487977 DOI: 10.1007/S00259-018-3969-4 |
0.348 |
|
2018 |
Peters F, Salihoglu H, Rodrigues E, Herzog E, Blume T, Filser S, Dorostkar M, Shimshek DR, Brose N, Neumann U, Herms J. BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology. Acta Neuropathologica. PMID 29327084 DOI: 10.1007/S00401-017-1804-9 |
0.582 |
|
2017 |
Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, et al. Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [(18)F]GE180 PET quantification. Neuroimage. PMID 28988133 DOI: 10.1016/J.Neuroimage.2017.10.006 |
0.575 |
|
2017 |
Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, et al. Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life-Span of Wild-Type Mice: A PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28705919 DOI: 10.2967/Jnumed.117.195107 |
0.594 |
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2017 |
Montagna E, Dorostkar MM, Herms J. The Role of APP in Structural Spine Plasticity. Frontiers in Molecular Neuroscience. 10: 136. PMID 28539872 DOI: 10.3389/Fnmol.2017.00136 |
0.315 |
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2017 |
Blumenstock S, Rodrigues EF, Peters F, Blazquez-Llorca L, Schmidt F, Giese A, Herms J. Seeding and transgenic overexpression of alpha-synuclein triggers dendritic spine pathology in the neocortex. Embo Molecular Medicine. PMID 28351932 DOI: 10.15252/Emmm.201607305 |
0.328 |
|
2017 |
Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, ... Herms J, et al. Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis. Frontiers in Aging Neuroscience. 9: 8. PMID 28197095 DOI: 10.3389/Fnagi.2017.00008 |
0.62 |
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2017 |
Rammes G, Mattusch C, Wulff M, Seeser F, Kreuzer M, Zhu K, Deussing JM, Herms J, Parsons CG. Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD). Neuropharmacology. PMID 28174113 DOI: 10.1016/J.Neuropharm.2017.02.003 |
0.399 |
|
2017 |
Blazquez-Llorca L, Valero-Freitag S, Rodrigues EF, Merchán-Pérez Á, Rodríguez JR, Dorostkar MM, DeFelipe J, Herms J. High plasticity of axonal pathology in Alzheimer's disease mouse models. Acta Neuropathologica Communications. 5: 14. PMID 28173876 DOI: 10.1186/S40478-017-0415-Y |
0.312 |
|
2017 |
Schön C, Herms J. In Vivo Imaging of Tau Aggregates in the Mouse Retina. Methods in Molecular Biology (Clifton, N.J.). 1523: 361-368. PMID 27975264 DOI: 10.1007/978-1-4939-6598-4_24 |
0.361 |
|
2017 |
Xu AJ, Marinkovic P, Herms J. Imaging Of Ageing And Seeding Effects On Tau Pathology In The Mouse Tauopathy Model Alzheimers & Dementia. 13: 1293. DOI: 10.1016/J.Jalz.2017.06.1957 |
0.309 |
|
2016 |
Zhu K, Xiang X, Filser S, Marinković P, Dorostkar MM, Crux S, Neumann U, Shimshek DR, Rammes G, Haass C, Lichtenthaler SF, Gunnersen JM, Herms J. Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6. Biological Psychiatry. PMID 28129943 DOI: 10.1016/J.Biopsych.2016.12.023 |
0.352 |
|
2016 |
Ovsepian SV, Blazquez-Llorca L, Freitag SV, Rodrigues EF, Herms J. Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors. Cerebral Cortex (New York, N.Y. : 1991). PMID 27600841 DOI: 10.1093/Cercor/Bhw267 |
0.354 |
|
2016 |
Zou C, Crux S, Marinesco S, Montagna E, Sgobio C, Shi Y, Shi S, Zhu K, Dorostkar MM, Müller UC, Herms J. Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis. The Embo Journal. PMID 27572463 DOI: 10.15252/Embj.201694085 |
0.342 |
|
2016 |
Overhoff F, Brendel M, Jaworska A, Korzhova V, Delker A, Probst F, Focke C, Gildehaus FJ, Carlsen J, Baumann K, Haass C, Bartenstein P, Herms J, Rominger A. Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice. Frontiers in Neuroscience. 10: 45. PMID 26973442 DOI: 10.3389/Fnins.2016.00045 |
0.607 |
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2016 |
Brendel M, Jaworska A, Probst F, Overhoff F, Korzhova V, Lindner S, Carlsen J, Bartenstein P, Harada R, Kudo Y, Haass C, van Leuven F, Okamura N, Herms J, Rominger A. microPET Imaging of Tau Pathology with [18F]-THK5117 in two Transgenic Mouse Models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26912432 DOI: 10.2967/Jnumed.115.163493 |
0.692 |
|
2016 |
Brendel M, Probst F, Jaworska A, Overhoff F, Korzhova V, Albert N, Beck R, Lindner S, Gildehaus FJ, Baumann K, Bartenstein P, Kleinberger G, Haass C, Herms J, Rominger A. Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple Tracer PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26912428 DOI: 10.2967/Jnumed.115.167858 |
0.609 |
|
2016 |
Herms J, Dorostkar MM. Dendritic Spine Pathology in Neurodegenerative Diseases. Annual Review of Pathology. PMID 26907528 DOI: 10.1146/Annurev-Pathol-012615-044216 |
0.34 |
|
2016 |
Zou C, Shi Y, Ohli J, Schüller U, Dorostkar MM, Herms J. Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer's disease. Acta Neuropathologica. PMID 26724934 DOI: 10.1007/S00401-015-1527-8 |
0.399 |
|
2015 |
Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Monitoring of chronic γ-secretase modulator treatment by serial amyloid-PET. Molecular Psychiatry. 20: 1141. PMID 26401838 DOI: 10.1038/mp.2015.146 |
0.518 |
|
2015 |
Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, ... ... Herms J, et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. PMID 26322584 DOI: 10.1038/Nature14864 |
0.358 |
|
2015 |
Dorostkar MM, Zou C, Blazquez-Llorca L, Herms J. Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities. Acta Neuropathologica. 130: 1-19. PMID 26063233 DOI: 10.1007/S00401-015-1449-5 |
0.371 |
|
2015 |
Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment. Molecular Psychiatry. 20: 1179-87. PMID 26055427 DOI: 10.1038/mp.2015.74 |
0.349 |
|
2015 |
Zou C, Montagna E, Shi Y, Peters F, Blazquez-Llorca L, Shi S, Filser S, Dorostkar MM, Herms J. Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease. Acta Neuropathologica. 129: 909-20. PMID 25862638 DOI: 10.1007/S00401-015-1421-4 |
0.428 |
|
2015 |
Jung CK, Keppler K, Steinbach S, Blazquez-Llorca L, Herms J. Fibrillar amyloid plaque formation precedes microglial activation. Plos One. 10: e0119768. PMID 25799372 DOI: 10.1371/Journal.Pone.0119768 |
0.406 |
|
2015 |
Blazquez-Llorca L, Hummel E, Zimmerman H, Zou C, Burgold S, Rietdorf J, Herms J. Correlation of two-photon in vivo imaging and FIB/SEM microscopy. Journal of Microscopy. 259: 129-36. PMID 25786682 DOI: 10.1111/Jmi.12231 |
0.312 |
|
2015 |
Brendel M, Jaworska A, Grießinger E, Rötzer C, Burgold S, Gildehaus FJ, Carlsen J, Cumming P, Baumann K, Haass C, Steiner H, Bartenstein P, Herms J, Rominger A. Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models. Plos One. 10: e0116678. PMID 25706990 DOI: 10.1371/Journal.Pone.0116678 |
0.604 |
|
2015 |
Filser S, Ovsepian SV, Masana M, Blazquez-Llorca L, Brandt Elvang A, Volbracht C, Müller MB, Jung CK, Herms J. Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions. Biological Psychiatry. 77: 729-39. PMID 25599931 DOI: 10.1016/J.Biopsych.2014.10.013 |
0.352 |
|
2015 |
Thon N, Kunz M, Lemke L, Jansen NL, Eigenbrod S, Kreth S, Lutz J, Egensperger R, Giese A, Herms J, Weller M, Kretzschmar H, Tonn JC, La Fougère C, Kreth FW. Dynamic 18F-FET PET in suspected WHO grade II gliomas defines distinct biological subgroups with different clinical courses International Journal of Cancer. 136: 2132-2145. PMID 25311315 DOI: 10.1002/Ijc.29259 |
0.355 |
|
2015 |
Ochs SM, Dorostkar MM, Aramuni G, Schön C, Filser S, Pöschl J, Kremer A, Van Leuven F, Ovsepian SV, Herms J. Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin. Molecular Psychiatry. 20: 482-9. PMID 24912492 DOI: 10.1038/Mp.2014.55 |
0.528 |
|
2015 |
Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment Molecular Psychiatry. DOI: 10.1038/mp.2015.74 |
0.515 |
|
2014 |
Honarnejad K, Daschner A, Gehring AP, Szybinska A, Giese A, Kuznicki J, Bracher F, Herms J. Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease. Translational Psychiatry. 4: e489. PMID 25514752 DOI: 10.1038/Tp.2014.132 |
0.364 |
|
2014 |
Dorostkar MM, Burgold S, Filser S, Barghorn S, Schmidt B, Anumala URa, Hillen H, Klein C, Herms J. Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model Brain : a Journal of Neurology. 137: 3319-3326. PMID 25281869 DOI: 10.1093/Brain/Awu280 |
0.403 |
|
2014 |
Kleele T, Marinkovi? P, Williams PR, Stern S, Weigand EE, Engerer P, Naumann R, Hartmann J, Karl RM, Bradke F, Bishop D, Herms J, Konnerth A, Kerschensteiner M, Godinho L, et al. An assay to image neuronal microtubule dynamics in mice. Nature Communications. 5: 4827. PMID 25219969 DOI: 10.1038/Ncomms5827 |
0.304 |
|
2014 |
Neuner J, Ovsepian SV, Dorostkar M, Filser S, Gupta A, Michalakis S, Biel M, Herms J. Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb. Nature Communications. 5: 3915. PMID 24867427 DOI: 10.1038/Ncomms4915 |
0.308 |
|
2014 |
Burgold S, Filser S, Dorostkar MM, Schmidt B, Herms J. In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques Acta Neuropathologica Communications. 2: 30. PMID 24678659 DOI: 10.1186/2051-5960-2-30 |
0.381 |
|
2014 |
Brendel M, Delker A, Rötzer C, Böning G, Carlsen J, Cyran C, Mille E, Gildehaus FJ, Cumming P, Baumann K, Steiner H, Haass C, Herms J, Bartenstein P, Rominger A. Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-Swe mice using [(18)F]-florbetaben PET. Neuroimage. 84: 843-53. PMID 24055703 DOI: 10.1016/J.Neuroimage.2013.09.017 |
0.639 |
|
2014 |
Ovsepian SV, Antyborzec I, O'Leary VB, Zaborszky L, Herms J, Oliver Dolly J. Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons. Brain Structure & Function. 219: 1527-41. PMID 23716278 DOI: 10.1007/S00429-013-0583-X |
0.336 |
|
2014 |
Rominger A, Brendel M, Rötzer C, Gildehaus F, Baumann K, Haass C, Steiner H, Herms J, Bartenstein P. Monitoring Of Long-Term Gamma Secretase Modulation Treatment In App-Swe Mice By Means Of [18F]-Florbetaben Pet Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.113 |
0.578 |
|
2013 |
Ovsepian SV, Herms J. Cholinergic neurons-keeping check on amyloid β in the cerebral cortex. Frontiers in Cellular Neuroscience. 7: 252. PMID 24376398 DOI: 10.3389/Fncel.2013.00252 |
0.339 |
|
2013 |
Hoffmann NA, Dorostkar MM, Blumenstock S, Goedert M, Herms J. Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice. Acta Neuropathologica Communications. 1: 82. PMID 24344647 DOI: 10.1186/2051-5960-1-82 |
0.394 |
|
2013 |
Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J. Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease Plos One. 8. PMID 24260442 DOI: 10.1371/Journal.Pone.0080645 |
0.307 |
|
2013 |
Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J, Herms J. FRET-based calcium imaging: A tool for high-throughput/content phenotypic drug screening in alzheimer disease Journal of Biomolecular Screening. 18: 1309-1320. PMID 24221842 DOI: 10.1177/1087057113502672 |
0.311 |
|
2013 |
Anumala UR, Gu J, Lo Monte F, Kramer T, Heyny-von Haußen R, Hölzer J, Goetschy-Meyer V, Schön C, Mall G, Hilger I, Czech C, Herms J, Schmidt B. Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer's disease brains. Bioorganic & Medicinal Chemistry. 21: 5139-44. PMID 23859773 DOI: 10.1016/J.Bmc.2013.06.039 |
0.336 |
|
2013 |
Ovsepian SV, Herms J. Drain of the brain: Low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system Neurobiology of Aging. 34: 2517-2524. PMID 23747048 DOI: 10.1016/J.Neurobiolaging.2013.05.005 |
0.345 |
|
2013 |
Rominger A, Brendel M, Burgold S, Keppler K, Baumann K, Xiong G, Mille E, Gildehaus FJ, Carlsen J, Schlichtiger J, Niedermoser S, Wängler B, Cumming P, Steiner H, Herms J, et al. Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1127-34. PMID 23729696 DOI: 10.2967/Jnumed.112.114660 |
0.642 |
|
2013 |
Honarnejad K, Jung CKE, Lammich S, Arzberger T, Kretzschmar H, Herms J. Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease Journal of Cellular and Molecular Medicine. 17: 293-302. PMID 23379308 DOI: 10.1111/Jcmm.12008 |
0.314 |
|
2013 |
Brendel M, Böning G, Delker A, Rötzer C, Gildehaus F, Baumann K, Steiner H, Haass C, Herms J, Bartenstein P, Rominger A. PET imaging using [18F]florbetaben in Alzheimer's disease mouse models Alzheimers & Dementia. 9: 29. DOI: 10.1016/J.Jalz.2013.05.041 |
0.601 |
|
2012 |
Schön C, Hoffmann NA, Ochs SM, Burgold S, Filser S, Steinbach S, Seeliger MW, Arzberger T, Goedert M, Kretzschmar HA, Schmidt B, Herms J. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice. Plos One. 7: e53547. PMID 23300938 DOI: 10.1371/Journal.Pone.0053547 |
0.393 |
|
2012 |
Dorostkar MM, Herms J. Arc illuminates Alzheimer's pathophysiology Nature Neuroscience. 15: 1323-1325. PMID 23007183 DOI: 10.1038/Nn.3226 |
0.346 |
|
2012 |
Bittner T, Burgold S, Dorostkar MM, Fuhrmann M, Wegenast-Braun BM, Schmidt B, Kretzschmar H, Herms J. Amyloid plaque formation precedes dendritic spine loss Acta Neuropathologica. 124: 797-807. PMID 22993126 DOI: 10.1007/S00401-012-1047-8 |
0.371 |
|
2012 |
Boländer A, Kieser D, Voss C, Bauer S, Schön C, Burgold S, Bittner T, Hölzer J, Heyny-Von Haußen R, Mall G, Goetschy V, Czech C, Knust H, Berger R, Herms J, et al. Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines As imaging agents for tau fibrils and β-Amyloid plaques in alzheimers disease models Journal of Medicinal Chemistry. 55: 9170-9180. PMID 22913544 DOI: 10.1021/Jm300653B |
0.399 |
|
2012 |
Honarnejad K, Herms J. Presenilins: Role in calcium homeostasis International Journal of Biochemistry and Cell Biology. 44: 1983-1986. PMID 22842534 DOI: 10.1016/J.Biocel.2012.07.019 |
0.304 |
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2012 |
Frick A, Grammel D, Schmidt F, Pöschl J, Priller M, Pagella P, von Bueren AO, Peraud A, Tonn JC, Herms J, Rutkowski S, Kretzschmar HA, Schüller U. Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons. Glia. 60: 820-32. PMID 22374686 DOI: 10.1002/Glia.22314 |
0.306 |
|
2012 |
Jung CKE, Herms J. Role of APP for dendritic spine formation and stability Experimental Brain Research. 217: 463-470. PMID 22094714 DOI: 10.1007/S00221-011-2939-X |
0.372 |
|
2012 |
Hokkanen S, Feldmann HM, Ding H, Jung CKE, Bojarski L, ller IRM, Schüller U, Kretzschmar H, Wolf E, Herms J. Lack of pur-alpha alters postnatal brain development and causes megalencephaly Human Molecular Genetics. 21: 473-484. PMID 22010047 DOI: 10.1093/Hmg/Ddr476 |
0.342 |
|
2012 |
Rominger A, Brendel M, Baumann K, Gildehaus F, Niedermoser S, Wängler B, Burgold S, Herms J, Cumming P, Steiner H, Haass C, Bartenstein P. Longitudinal imaging of cerebral beta-amyloid in APP-swe mice using [18F]florbetaben PET Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.411 |
0.598 |
|
2012 |
Rominger A, Brendel M, Baumann K, Gildehaus F, Niedermoser S, Wängler B, Burgold S, Herms J, Cumming P, Steiner H, Haass C, Bartenstein P. Longitudinal imaging of cerebral Aβ in APP-Swe mice using [18F]florbetaben PET Alzheimers & Dementia. 8: 11. DOI: 10.1016/J.Jalz.2012.05.033 |
0.615 |
|
2011 |
Jung CK, Fuhrmann M, Honarnejad K, Van Leuven F, Herms J. Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo. Journal of Neurochemistry. 119: 1064-73. PMID 21951279 DOI: 10.1111/J.1471-4159.2011.07503.X |
0.561 |
|
2011 |
Pöschl J, Lorenz A, Hartmann W, von Bueren AO, Kool M, Li S, Peraud A, Tonn JC, Herms J, Xiang M, Rutkowski S, Kretzschmar HA, Schüller U. Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans. Oncogene. 30: 4721-30. PMID 21602885 DOI: 10.1038/Onc.2011.173 |
0.335 |
|
2011 |
Hüls S, Högen T, Vassallo N, Danzer KM, Hengerer B, Giese A, Herms J. AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers Journal of Neurochemistry. 117: 868-878. PMID 21426349 DOI: 10.1111/J.1471-4159.2011.07254.X |
0.3 |
|
2011 |
Kunz M, Thon N, Eigenbrod S, Hartmann C, Egensperger R, Herms J, Geisler J, la Fougere C, Lutz J, Linn J, Kreth S, von Deimling A, Tonn JC, Kretzschmar HA, Pöpperl G, et al. Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas. Neuro-Oncology. 13: 307-16. PMID 21292686 DOI: 10.1093/Neuonc/Noq196 |
0.308 |
|
2011 |
Burgold S, Bittner T, Dorostkar MM, Kieser D, Fuhrmann M, Mitteregger G, Kretzschmar H, Schmidt B, Herms J. In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks Acta Neuropathologica. 121: 327-335. PMID 21136067 DOI: 10.1007/S00401-010-0787-6 |
0.395 |
|
2011 |
Schmidt B, Kieser D, Boländer A, Haussen RH, Burgold S, Herms J. Fluorescent dyes detect Aβ- and Tau-pathology post mortem and in vivo Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.888 |
0.303 |
|
2011 |
Herms J, Bittner T, Fuhrmann M, Burgold S, Nadine H, Jung C. Tau dependent spine loss in Alzheimer's disease mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1990 |
0.373 |
|
2011 |
Fuhrmann M, Ochs S, Keppler K, Langer A, Hoelter S, Herms J. Role of chemokine receptor CX3CR1 in Alzheimer's transgenic mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1590 |
0.33 |
|
2010 |
Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J. Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. Plos One. 5: e15477. PMID 21103384 DOI: 10.1371/Journal.Pone.0015477 |
0.413 |
|
2010 |
Fuhrmann M, Bittner T, Jung CK, Burgold S, Page RM, Mitteregger G, Haass C, LaFerla FM, Kretzschmar H, Herms J. Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nature Neuroscience. 13: 411-3. PMID 20305648 DOI: 10.1038/Nn.2511 |
0.353 |
|
2009 |
Bittner T, Fuhrmann M, Burgold S, Jung CK, Volbracht C, Steiner H, Mitteregger G, Kretzschmar HA, Haass C, Herms J. Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10405-9. PMID 19692615 DOI: 10.1523/Jneurosci.2288-09.2009 |
0.39 |
|
2009 |
Mitteregger G, Korte S, Shakarami M, Herms J, Kretzschmar HA. Role of copper and manganese in prion disease progression. Brain Research. 1292: 155-64. PMID 19635464 DOI: 10.1016/J.Brainres.2009.07.051 |
0.309 |
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2009 |
Priller C, Mitteregger G, Paluch S, Vassallo N, Staufenbiel M, Kretzschmar HA, Jucker M, Herms J. Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice. Neurobiology of Aging. 30: 1227-37. PMID 18077058 DOI: 10.1016/J.Neurobiolaging.2007.10.016 |
0.336 |
|
2009 |
Dewachter I, Filipkowski RK, Priller C, Ris L, Neyton J, Croes S, Terwel D, Gysemans M, Devijver H, Borghgraef P, Godaux E, Kaczmarek L, Herms J, Van Leuven F. Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice. Neurobiology of Aging. 30: 241-56. PMID 17673336 DOI: 10.1016/J.Neurobiolaging.2007.06.011 |
0.518 |
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2009 |
Fuhrmann M, Bittner T, Jung C, Burgold S, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J. Microglia mediated and fractalkine receptor dependent neuron loss in a mouse model of Alzheimer's disease Alzheimers & Dementia. 5: 82. DOI: 10.1016/J.Jalz.2009.05.207 |
0.33 |
|
2009 |
Burgold S, Fuhrmann M, Schmidt B, Kretzschmar H, Herms J. Kinetics of dendritic structural plasticity in the living brain of an Alzheimer's disease mouse model acquired with two photon microscopy Alzheimers & Dementia. 5: 439. DOI: 10.1016/J.Jalz.2009.04.897 |
0.349 |
|
2009 |
Bittner T, Fuhrmann M, Burgold S, Kretzschmar H, LaFerla FM, Herms J. Long-term in vivo imaging identifies multiple events that trigger dendritic spine loss in 3xTg-AD mice Alzheimers & Dementia. 5: 438. DOI: 10.1016/J.Jalz.2009.04.894 |
0.344 |
|
2009 |
Jung CKE, Honarnejad K, Leuven FV, Herms J. In vivo analysis of the effect of mutant PS1 on dendritic spines in the somatosensory cortex of transgenic mice Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.04.506 |
0.304 |
|
2009 |
Hoffmann NA, Bittner T, Burgold S, LaFerla FM, Kretzschmar HA, Herms J. P3-181: Ultrastructural investigation of tau-dependent dendropathy in a triple transgenic mouse model of Alzheimer's disease Alzheimer's & Dementia. 5: P396-P397. DOI: 10.1016/J.Jalz.2009.04.1055 |
0.368 |
|
2008 |
Mehrkens JH, Pp̈pperl G, Rachinger W, Herms J, Seelos K, Tatsch K, Tonn JC, Kreth FW. The positive predictive value of O-(2-[18F]fluoroethyl)-l- tyrosine (FET) PET in the diagnosis of a glioma recurrence after multimodal treatment Journal of Neuro-Oncology. 88: 27-35. PMID 18217207 DOI: 10.1007/S11060-008-9526-4 |
0.347 |
|
2008 |
Bojarski L, Herms J, Kuznicki J. Calcium dysregulation in Alzheimer's disease Neurochemistry International. 52: 621-633. PMID 18035450 DOI: 10.1016/J.Neuint.2007.10.002 |
0.345 |
|
2008 |
Linn J, Herms J, Dichgans M, Brückmann H, Fesl G, Freilinger T, Wiesmann M. Subarachnoid hemosiderosis and superficial cortical hemosiderosis in cerebral amyloid angiopathy. Ajnr. American Journal of Neuroradiology. 29: 184-6. PMID 17947366 DOI: 10.3174/Ajnr.A0783 |
0.319 |
|
2007 |
Pöpperl G, Kreth FW, Mehrkens JH, Herms J, Seelos K, Koch W, Gildehaus FJ, Kretzschmar HA, Tonn JC, Tatsch K. FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading. European Journal of Nuclear Medicine and Molecular Imaging. 34: 1933-42. PMID 17763848 DOI: 10.1007/S00259-007-0534-Y |
0.32 |
|
2007 |
Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, Herms J, Buchholz C, Eckman CB, Korte M, Wolfer DP, Müller UC. The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7817-26. PMID 17634375 DOI: 10.1523/Jneurosci.1026-07.2007 |
0.389 |
|
2007 |
Fuhrmann M, Mitteregger G, Kretzschmar H, Herms J. Dendritic pathology in prion disease starts at the synaptic spine Journal of Neuroscience. 27: 6224-6233. PMID 17553995 DOI: 10.1523/Jneurosci.5062-06.2007 |
0.32 |
|
2007 |
Priller C, Dewachter I, Vassallo N, Paluch S, Pace C, Kretzschmar HA, Van Leuven F, Herms J. Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons. The Journal of Biological Chemistry. 282: 1119-27. PMID 17088253 DOI: 10.1074/Jbc.M605066200 |
0.528 |
|
2006 |
Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA, Herms J. Synapse formation and function is modulated by the amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7212-21. PMID 16822978 DOI: 10.1523/Jneurosci.1450-06.2006 |
0.327 |
|
2005 |
Rachinger W, Goetz C, Pöpperl G, Gildehaus FJ, Kreth FW, Holtmannspötter M, Herms J, Koch W, Tatsch K, Tonn JC. Positron emission tomography with O-(2-[18F]flouroethyl)-L- tyrosine versus magnetic resonance imaging in the diagnosis of recurrent gliomas Neurosurgery. 57: 505-511. PMID 16145529 DOI: 10.1227/01.Neu.0000171642.49553.B0 |
0.328 |
|
2004 |
Herms J, Anliker B, Heber S, Ring S, Fuhrmann M, Kretzschmar H, Sisodia S, Müller U. Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members Embo Journal. 23: 4106-4115. PMID 15385965 DOI: 10.1038/Sj.Emboj.7600390 |
0.35 |
|
2003 |
Herms J, Schneider I, Dewachter I, Caluwaerts N, Kretzschmar H, Van Leuven F. Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein. The Journal of Biological Chemistry. 278: 2484-9. PMID 12431992 DOI: 10.1074/Jbc.M206769200 |
0.525 |
|
2001 |
Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F, Herms J. Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. The Journal of Biological Chemistry. 276: 11539-44. PMID 11278803 DOI: 10.1074/Jbc.M010977200 |
0.56 |
|
2001 |
Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW, Brose N. The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 10-7. PMID 11150314 DOI: 10.1523/Jneurosci.21-01-00010.2001 |
0.469 |
|
2000 |
Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rulicke T, Kretzschmar H, Von Koch C, Sisodia S, Tremml P, Lipp HP, Wolfer DP, Muller U. Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members Journal of Neuroscience. 20: 7951-7963. PMID 11050115 DOI: 10.1523/Jneurosci.20-21-07951.2000 |
0.363 |
|
1999 |
Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N, Kretzschmar H. Evidence of presynaptic location and function of the prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8866-75. PMID 10516306 DOI: 10.1523/Jneurosci.19-20-08866.1999 |
0.526 |
|
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