| Year |
Citation |
Score |
| 2024 |
McArthur N, Squire JD, Onyeachonam OJ, Bhatt NN, Jerez C, Holberton AL, Tessier PM, Wood LB, Kayed R, Kane RS. Generation of nanobodies with conformational specificity for tau oligomers that recognize tau aggregates from human Alzheimer's disease samples. Biomaterials Science. PMID 39434503 DOI: 10.1039/d4bm00707g |
0.502 |
|
| 2024 |
Davis MR, Robinson E, Koronyo Y, Salobrar-Garcia E, Rentsendorj A, Gaire BP, Mirzaei N, Kayed R, Sadun AA, Ljubimov AV, Schneider LS, Hawes D, Black KL, Fuchs DT, Koronyo-Hamaoui M. Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease. Biorxiv : the Preprint Server For Biology. PMID 39345568 DOI: 10.1101/2024.09.17.613293 |
0.403 |
|
| 2024 |
Scaduto P, Marcatti M, Bhatt N, Kayed R, Taglialatela G. Calcineurin inhibition prevents synaptic plasticity deficit induced by brain-derived tau oligomers. Brain Communications. 6: fcae277. PMID 39239152 DOI: 10.1093/braincomms/fcae277 |
0.431 |
|
| 2024 |
Marcatti M, Tumurbaatar B, Borghi M, Guptarak J, Zhang WR, Krishnan B, Kayed R, Fracassi A, Taglialatela G. Inhibition of Calcineurin with FK506 Reduces Tau Levels and Attenuates Synaptic Impairment Driven by Tau Oligomers in the Hippocampus of Male Mouse Models. International Journal of Molecular Sciences. 25. PMID 39201779 DOI: 10.3390/ijms25169092 |
0.399 |
|
| 2024 |
Bhopatkar AA, Bhatt N, Haque MA, Xavier R, Fung L, Jerez C, Kayed R. MAPT mutations associated with familial tauopathies lead to formation of conformationally distinct oligomers that have cross-seeding ability. Protein Science : a Publication of the Protein Society. 33: e5099. PMID 39145409 DOI: 10.1002/pro.5099 |
0.407 |
|
| 2024 |
Theofilas P, Wang C, Butler D, Morales DO, Petersen C, Ambrose A, Chin B, Yang T, Khan S, Ng R, Kayed R, Karch CM, Miller BL, Gestwicki JE, Gan L, et al. iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death. Molecular and Cellular Neurosciences. 103954. PMID 39032719 DOI: 10.1016/j.mcn.2024.103954 |
0.444 |
|
| 2024 |
Shi H, Mirzaei N, Koronyo Y, Davis MR, Robinson E, Braun GM, Jallow O, Rentsendorj A, Ramanujan VK, Fert-Bober J, Kramerov AA, Ljubimov AV, Schneider LS, Tourtellotte WG, Hawes D, ... ... Kayed R, et al. Identification of retinal oligomeric, citrullinated, and other tau isoforms in early and advanced AD and relations to disease status. Acta Neuropathologica. 148: 3. PMID 38980423 DOI: 10.1007/s00401-024-02760-8 |
0.417 |
|
| 2024 |
Gaikwad S, Puangmalai N, Sonawane M, Montalbano M, Price R, Iyer MS, Ray A, Moreno S, Kayed R. Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice. Science Translational Medicine. 16: eadj5958. PMID 38959324 DOI: 10.1126/scitranslmed.adj5958 |
0.461 |
|
| 2024 |
McArthur N, Kang B, Rivera Moctezuma FG, Shaikh AT, Loeffler K, Bhatt NN, Kidd M, Zupancic JM, Desai AA, Djeddar N, Bryksin A, Tessier PM, Kayed R, Wood LB, Kane RS. Development of a pan-tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates. Biotechnology Progress. e3463. PMID 38568030 DOI: 10.1002/btpr.3463 |
0.457 |
|
| 2024 |
Sengupta U, Kayed R. Tau Oligomers as Pathogenic Seeds: Preparation, Characterization, and Propagation In Vitro and In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2754: 147-183. PMID 38512666 DOI: 10.1007/978-1-0716-3629-9_9 |
0.402 |
|
| 2024 |
Arar S, Haque MA, Bhatt N, Zhao Y, Kayed R. Effect of Natural Osmolytes on Recombinant Tau Monomer: Propensity of Oligomerization and Aggregation. Acs Chemical Neuroscience. PMID 38503425 DOI: 10.1021/acschemneuro.3c00614 |
0.505 |
|
| 2024 |
Shi H, Mirzaei N, Koronyo Y, Davis MR, Robinson E, Braun GM, Jallow O, Rentsendorj A, Ramanujan VK, Fert-Bober J, Kramerov AA, Ljubimov AV, Schneider LS, Tourtellotte WG, Hawes D, ... ... Kayed R, et al. Identification of retinal tau oligomers, citrullinated tau, and other tau isoforms in early and advanced AD and relations to disease status. Biorxiv : the Preprint Server For Biology. PMID 38405854 DOI: 10.1101/2024.02.13.579999 |
0.43 |
|
| 2024 |
Bhatt N, Puangmalai N, Sengupta U, Jerez C, Kidd M, Gandhi S, Kayed R. C9orf72-associated dipeptide protein repeats form A11-positive oligomers in amyotrophic lateral sclerosis and frontotemporal dementia. The Journal of Biological Chemistry. 300: 105628. PMID 38295729 DOI: 10.1016/j.jbc.2024.105628 |
0.435 |
|
| 2023 |
Puangmalai N, Bhatt N, Bittar A, Jerez C, Shchankin N, Kayed R. Traumatic brain injury derived pathological tau polymorphs induce the distinct propagation pattern and neuroinflammatory response in wild type mice. Progress in Neurobiology. 232: 102562. PMID 38135105 DOI: 10.1016/j.pneurobio.2023.102562 |
0.37 |
|
| 2023 |
Gaikwad S, Senapati S, Haque MA, Kayed R. Senescence, brain inflammation, and oligomeric tau drive cognitive decline in Alzheimer's disease: Evidence from clinical and preclinical studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37814508 DOI: 10.1002/alz.13490 |
0.343 |
|
| 2023 |
Solorzano A, Brady M, Bhatt N, Johnson A, Burgess B, Leyva H, Puangmalai N, Jerez C, Wood R, Kayed R, Deane R. Central and peripheral tau retention modulated by an anti-tau antibody. Biorxiv : the Preprint Server For Biology. PMID 37645819 DOI: 10.1101/2023.08.17.553682 |
0.381 |
|
| 2023 |
Bhopatkar AA, Kayed R. Flanking regions, amyloid cores, and polymorphism: the potential interplay underlying structural diversity. The Journal of Biological Chemistry. 299: 105122. PMID 37536631 DOI: 10.1016/j.jbc.2023.105122 |
0.376 |
|
| 2023 |
Arar S, Haque MA, Kayed R. Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics. Proteins. PMID 37530227 DOI: 10.1002/prot.26561 |
0.445 |
|
| 2023 |
Hussong SA, Banh AQ, Van Skike CE, Dorigatti AO, Hernandez SF, Hart MJ, Ferran B, Makhlouf H, Gaczynska M, Osmulski PA, McAllen SA, Dineley KT, Ungvari Z, Perez VI, Kayed R, et al. Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy. Nature Communications. 14: 2367. PMID 37185259 DOI: 10.1038/s41467-023-37840-y |
0.404 |
|
| 2023 |
Luciani M, Montalbano M, Troncone L, Bacchin C, Uchida K, Daniele G, Jacobs Wolf B, Butler HM, Kiel J, Berto S, Gensemer C, Moore K, Morningstar J, Diteepeng T, Albayram O, ... ... Kayed R, et al. Big tau aggregation disrupts microtubule tyrosination and causes myocardial diastolic dysfunction: from discovery to therapy. European Heart Journal. 44: 1560-1570. PMID 37122097 DOI: 10.1093/eurheartj/ehad205 |
0.454 |
|
| 2022 |
Dhakal S, Robang AS, Bhatt N, Puangmalai N, Fung L, Kayed R, Paravastu AK, Rangachari V. Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein. The Journal of Biological Chemistry. 102498. PMID 36116552 DOI: 10.1016/j.jbc.2022.102498 |
0.446 |
|
| 2022 |
Montalbano M, Majmundar L, Sengupta U, Fung L, Kayed R. Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies. Brain Pathology (Zurich, Switzerland). e13112. PMID 36054524 DOI: 10.1111/bpa.13112 |
0.449 |
|
| 2022 |
Bhatt N, Kayed R. Quantification and targeting of elusive neurotoxic amyloid oligomers. Cell Reports. Medicine. 3: 100636. PMID 35584632 DOI: 10.1016/j.xcrm.2022.100636 |
0.391 |
|
| 2022 |
Clark JS, Kayed R, Abate G, Uberti D, Kinnon P, Piccirella S. Post-translational Modifications of the p53 Protein and the Impact in Alzheimer's Disease: A Review of the Literature. Frontiers in Aging Neuroscience. 14: 835288. PMID 35572126 DOI: 10.3389/fnagi.2022.835288 |
0.405 |
|
| 2022 |
Sengupta U, Kayed R. Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases. Progress in Neurobiology. 214: 102270. PMID 35447272 DOI: 10.1016/j.pneurobio.2022.102270 |
0.478 |
|
| 2022 |
Marcatti M, Fracassi A, Montalbano M, Natarajan C, Krishnan B, Kayed R, Taglialatela G. Aβ/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer's disease. Cellular and Molecular Life Sciences : Cmls. 79: 222. PMID 35377002 DOI: 10.1007/s00018-022-04255-9 |
0.422 |
|
| 2022 |
Puangmalai N, Sengupta U, Bhatt N, Gaikwad S, Montalbano M, Bhuyan A, Garcia S, McAllen S, Sonawane M, Jerez C, Zhao Y, Kayed R. Lysine 63-linked ubiquitination of tau oligomers contributes to the pathogenesis of Alzheimer's disease. The Journal of Biological Chemistry. 298: 101766. PMID 35202653 DOI: 10.1016/j.jbc.2022.101766 |
0.431 |
|
| 2022 |
Durell SR, Kayed R, Guy HR. The amyloid concentric β-barrel hypothesis: Models of amyloid beta 42 oligomers and annular protofibrils. Proteins. PMID 35038191 DOI: 10.1002/prot.26301 |
0.346 |
|
| 2021 |
Montalbano M, Jaworski E, Garcia S, Ellsworth A, McAllen S, Routh A, Kayed R. Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes. Frontiers in Molecular Neuroscience. 14: 742790. PMID 34924950 DOI: 10.3389/fnmol.2021.742790 |
0.383 |
|
| 2021 |
Moreira GG, Cantrelle FX, Quezada A, Carvalho FS, Cristóvão JS, Sengupta U, Puangmalai N, Carapeto AP, Rodrigues MS, Cardoso I, Fritz G, Herrera F, Kayed R, Landrieu I, Gomes CM. Dynamic interactions and Ca-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding. Nature Communications. 12: 6292. PMID 34725360 DOI: 10.1038/s41467-021-26584-2 |
0.437 |
|
| 2021 |
Gaikwad S, Puangmalai N, Bittar A, Montalbano M, Garcia S, McAllen S, Bhatt N, Sonawane M, Sengupta U, Kayed R. Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia. Cell Reports. 36: 109419. PMID 34289368 DOI: 10.1016/j.celrep.2021.109419 |
0.353 |
|
| 2021 |
Kayed R. Infectious Etiology and Amyloidosis in Alzheimer's Disease: The Puzzle Continues. The Journal of Biological Chemistry. 100936. PMID 34217702 DOI: 10.1016/j.jbc.2021.100936 |
0.379 |
|
| 2021 |
Lo Cascio F, Marzullo P, Kayed R, Palumbo Piccionello A. Curcumin as Scaffold for Drug Discovery against Neurodegenerative Diseases. Biomedicines. 9. PMID 33572457 DOI: 10.3390/biomedicines9020173 |
0.367 |
|
| 2021 |
Nguyen PH, Ramamoorthy A, Sahoo BR, Zheng J, Faller P, Straub JE, Dominguez L, Shea JE, Dokholyan NV, De Simone A, Ma B, Nussinov R, Najafi S, Ngo ST, Loquet A, ... ... Kayed R, et al. Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis. Chemical Reviews. PMID 33543942 DOI: 10.1021/acs.chemrev.0c01122 |
0.426 |
|
| 2020 |
Ruan Z, Pathak D, Venkatesan Kalavai S, Yoshii-Kitahara A, Muraoka S, Bhatt N, Takamatsu-Yukawa K, Hu J, Wang Y, Hersh S, Ericsson M, Gorantla S, Gendelman HE, Kayed R, Ikezu S, et al. Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. Brain : a Journal of Neurology. PMID 33246331 DOI: 10.1093/brain/awaa376 |
0.434 |
|
| 2020 |
Singh A, Allen D, Fracassi A, Tumurbaatar B, Natarajan C, Scaduto P, Woltjer R, Kayed R, Limon A, Krishnan B, Taglialatela G. Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology is Associated with Absence of Synaptic Tau Oligomers. Journal of Alzheimer's Disease : Jad. PMID 33185603 DOI: 10.3233/JAD-200716 |
0.362 |
|
| 2020 |
Montalbano M, McAllen S, Cascio FL, Sengupta U, Garcia S, Bhatt N, Ellsworth A, Heidelman EA, Johnson OD, Doskocil S, Kayed R. TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia. Neurobiology of Disease. 146: 105130. PMID 33065281 DOI: 10.1016/j.nbd.2020.105130 |
0.495 |
|
| 2020 |
Montalbano M, McAllen S, Puangmalai N, Sengupta U, Bhatt N, Johnson OD, Kharas MG, Kayed R. RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction. Nature Communications. 11: 4305. PMID 32855391 DOI: 10.1038/S41467-020-18022-6 |
0.583 |
|
| 2020 |
Farmer KM, Ghag G, Puangmalai N, Montalbano M, Bhatt N, Kayed R. P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease. Acta Neuropathologica Communications. 8: 132. PMID 32778161 DOI: 10.1186/S40478-020-01012-6 |
0.49 |
|
| 2020 |
Lo Cascio F, Garcia S, Montalbano M, Puangmalai N, McAllen S, Pace A, Palumbo Piccionello A, Kayed R. Modulating Disease-Relevant Tau Oligomeric Strains by Small Molecules. The Journal of Biological Chemistry. PMID 32737202 DOI: 10.1074/Jbc.Ra120.014630 |
0.602 |
|
| 2020 |
Kayed R, Dettmer U, Lesné SE. Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk. Journal of Parkinson's Disease. PMID 32508330 DOI: 10.3233/Jpd-201965 |
0.589 |
|
| 2020 |
Puangmalai N, Bhatt N, Montalbano M, Sengupta U, Gaikwad S, Ventura F, McAllen S, Ellsworth A, Garcia S, Kayed R. Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer's disease, progressive supranuclear palsy and dementia with Lewy bodies. Cell Death & Disease. 11: 314. PMID 32366836 DOI: 10.1038/S41419-020-2503-3 |
0.556 |
|
| 2020 |
Sengupta U, Puangmalai N, Bhatt N, Garcia S, Zhao Y, Kayed R. Polymorphic α-Synuclein Strains Modified by Dopamine and Docosahexaenoic Acid Interact Differentially with Tau Protein. Molecular Neurobiology. PMID 32350746 DOI: 10.1007/S12035-020-01913-6 |
0.449 |
|
| 2020 |
Marcatti M, Krishnan B, Kayed R, Taglialatela G. Differential dynamics of Aβ and tau oligomer synaptic binding may suggest diverse therapeutic targets for early vs. late Alzheimer's disease Alzheimer's & Dementia. 16. DOI: 10.1002/alz.038045 |
0.384 |
|
| 2019 |
Bittar A, Bhatt N, Kayed R. Advances and considerations in AD tau-targeted immunotherapy. Neurobiology of Disease. 104707. PMID 31841678 DOI: 10.1016/J.Nbd.2019.104707 |
0.536 |
|
| 2019 |
Lo Cascio F, Puangmalai N, Ellsworth A, Bucchieri F, Pace A, Palumbo Piccionello A, Kayed R. Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives. Scientific Reports. 9: 19011. PMID 31831807 DOI: 10.1038/S41598-019-55419-W |
0.577 |
|
| 2019 |
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, ... ... Kayed R, et al. NLRP3 inflammasome activation drives tau pathology. Nature. PMID 31748742 DOI: 10.1038/S41586-019-1769-Z |
0.562 |
|
| 2019 |
Derry PJ, Hegde ML, Jackson GR, Kayed R, Tour JM, Kent TA, Tsa AL. Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective. Progress in Neurobiology. 101716. PMID 31604111 DOI: 10.1016/J.Pneurobio.2019.101716 |
0.45 |
|
| 2019 |
Montalbano M, McAllen S, Sengupta U, Puangmalai N, Bhatt N, Ellsworth A, Kayed R. Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration. Aging Cell. e13035. PMID 31532069 DOI: 10.1111/Acel.13035 |
0.567 |
|
| 2019 |
Dasari AKR, Kayed R, Wi S, Lim KH. Tau interacts with the C-terminal region of α-synuclein, promoting formation of toxic aggregates with distinct molecular conformations. Biochemistry. PMID 31132261 DOI: 10.1021/Acs.Biochem.9B00215 |
0.467 |
|
| 2019 |
Olson A, Hussong SA, Kayed R, Galvan V. TAU-INDUCED ASTROCYTE SENESCENCE: A NOVEL MECHANISM FOR NEURONAL DYSFUNCTION IN ALZHEIMER’S DISEASE Innovation in Aging. 3: S91-S92. DOI: 10.1093/Geroni/Igz038.348 |
0.525 |
|
| 2019 |
Montalbano M, McAllen S, Sengupta U, Bhatt N, Ellsworth A, Kayed R. P4-520: TAU OLIGOMERS MEDIATE AGGREGATION OF RNA-BINDING PROTEINS MUSASHI1- AND MUSASHI2-INDUCING NUCLEAR MEMBRANE ALTERATION IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1513-P1513. DOI: 10.1016/J.Jalz.2019.08.066 |
0.475 |
|
| 2019 |
Kayed R. O4-01-04: POLYMORPHISM AND TOXIC INTERACTIONS BETWEEN SOLUBLE AMYLOID OLIGOMERS AND TAU Alzheimer's & Dementia. 15: P1230-P1230. DOI: 10.1016/j.jalz.2019.06.4743 |
0.347 |
|
| 2019 |
Kayed R. F2-06-04: POLYMORPHISM AND TOXIC INTERACTIONS BETWEEN SOLUBLE AMYLOID OLIGOMERS AND TAU Alzheimer's & Dementia. 15: P525-P526. DOI: 10.1016/J.Jalz.2019.06.4439 |
0.434 |
|
| 2019 |
Hussong SA, Skike CEV, Olson AB, Hart MJ, Hernandez SF, Banh A, McAllen S, Kayed R, Galvan V. P4-148: Propagation Of Soluble Tau Aggregates In Brain Microvascular Endothelial Cells Promotes Cellular Senescence/Sasp And Blocks Enos Activation Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3809 |
0.415 |
|
| 2019 |
Theofilas P, Hayath M, Wang C, Butler D, McAllen S, Arkin M, Gestwicki J, Cuervo AM, Kayed R, Karch CM, Temple S, Gan L, Grinberg LT. P3-200: Tau-Mediated Cell Death Mechanisms In Mapt V337M Ipsc-Derived Human Neurons Alzheimers & Dementia. 15: 1006. DOI: 10.1016/J.Jalz.2019.06.3229 |
0.326 |
|
| 2018 |
Sengupta U, Montalbano M, McAllen S, Minuesa G, Kharas M, Kayed R. Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease. Acta Neuropathologica Communications. 6: 113. PMID 30367664 DOI: 10.1186/S40478-018-0615-0 |
0.513 |
|
| 2018 |
Sengupta U, Kayed R. Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30206420 DOI: 10.1038/S41386-018-0204-8 |
0.498 |
|
| 2018 |
Wang P, Lo Cascio F, Gao J, Kayed R, Huang X. Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides. Chemical Communications (Cambridge, England). PMID 30128457 DOI: 10.1039/C8Cc05072D |
0.462 |
|
| 2018 |
Ghag G, Bhatt N, Cantu DV, Guerrero-Munoz MJ, Ellsworth A, Sengupta U, Kayed R. Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross-seeding behavior. Protein Science : a Publication of the Protein Society. PMID 30125425 DOI: 10.1002/Pro.3499 |
0.502 |
|
| 2018 |
Comerota MM, Tumurbaatar B, Krishnan B, Kayed R, Taglialatela G. Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies. Molecular Neurobiology. PMID 30120733 DOI: 10.1007/S12035-018-1248-9 |
0.481 |
|
| 2018 |
Sengupta U, Carretero-Murillo M, Kayed R. Preparation and Characterization of Tau Oligomer Strains. Methods in Molecular Biology (Clifton, N.J.). 1779: 113-146. PMID 29886531 DOI: 10.1007/978-1-4939-7816-8_9 |
0.392 |
|
| 2018 |
Krishnan B, Kayed R, Taglialatela G. Elevated phospholipase D isoform 1 in Alzheimer's disease patients' hippocampus: Relevance to synaptic dysfunction and memory deficits. Alzheimer's & Dementia (New York, N. Y.). 4: 89-102. PMID 29560412 DOI: 10.1016/J.Trci.2018.01.002 |
0.401 |
|
| 2018 |
Gerson JE, Farmer KM, Henson N, Castillo-Carranza DL, Carretero Murillo M, Sengupta U, Barrett A, Kayed R. Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy. Molecular Neurodegeneration. 13: 13. PMID 29544548 DOI: 10.1186/S13024-018-0245-9 |
0.509 |
|
| 2018 |
Bittar A, Sengupta U, Kayed R. Prospects for strain-specific immunotherapy in Alzheimer's disease and tauopathies. Npj Vaccines. 3: 9. PMID 29507776 DOI: 10.1038/s41541-018-0046-8 |
0.398 |
|
| 2018 |
Castillo-Carranza DL, Guerrero-Muñoz MJ, Sengupta U, Gerson JE, Kayed R. α-Synuclein Oligomers Induce a Unique Toxic Tau Strain. Biological Psychiatry. PMID 29478699 DOI: 10.1016/J.Biopsych.2017.12.018 |
0.503 |
|
| 2018 |
Lo Cascio F, Kayed R. Azure C Targets and Modulates Toxic Tau Oligomers. Acs Chemical Neuroscience. PMID 29378132 DOI: 10.1021/Acschemneuro.7B00501 |
0.586 |
|
| 2018 |
Aguilar CL, Al-Lahham R, Sengupta U, Carretero-Murillo M, Kayed R, Dineley KT. O4-05-04: Tau Immunotherapy for Alpha-Synucleinopathy Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2425 |
0.304 |
|
| 2017 |
Castillo-Carranza DL, Nilson AN, Van Skike CE, Jahrling JB, Patel K, Garach P, Gerson JE, Sengupta U, Abisambra J, Nelson P, Troncoso J, Ungvari Z, Galvan V, Kayed R. Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies. Aging and Disease. 8: 257-266. PMID 28580182 DOI: 10.14336/Ad.2017.0112 |
0.565 |
|
| 2017 |
Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE. Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533388 DOI: 10.1073/Pnas.1704698114 |
0.487 |
|
| 2017 |
Kolarova M, Sengupta U, Bartos A, Ricny J, Kayed R. Tau Oligomers in Sera of Patients with Alzheimer's Disease and Aged Controls. Journal of Alzheimer's Disease : Jad. PMID 28453485 DOI: 10.3233/Jad-170048 |
0.532 |
|
| 2017 |
Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 94: 278-293.e9. PMID 28426964 DOI: 10.1016/J.Neuron.2017.03.042 |
0.46 |
|
| 2017 |
Sengupta U, Portelius E, Hansson O, Farmer K, Castillo-Carranza D, Woltjer R, Zetterberg H, Galasko D, Blennow K, Kayed R. Tau oligomers in cerebrospinal fluid in Alzheimer's disease. Annals of Clinical and Translational Neurology. 4: 226-235. PMID 28382304 DOI: 10.1002/Acn3.382 |
0.532 |
|
| 2017 |
Gerson JE, Sengupta U, Kayed R. Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo. Methods in Molecular Biology (Clifton, N.J.). 1523: 141-157. PMID 27975249 DOI: 10.1007/978-1-4939-6598-4_9 |
0.506 |
|
| 2017 |
Farmer KM, Carretero-Murillo M, McAllen S, Sarkar P, Kayed R. TAU AND P53 IN ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P1505. DOI: 10.1016/J.Jalz.2017.07.617 |
0.452 |
|
| 2017 |
Bittar A, Hassan T, Bassal F, Lucke-Wold B, Logsdon A, Rosen C, Turner R, Kayed R. TBI AND AD: SIMILAR TAU-INDUCED NEURODEGENERATION? Alzheimer's & Dementia. 13: P1503-P1504. DOI: 10.1016/J.Jalz.2017.07.612 |
0.475 |
|
| 2017 |
Lo Cascio F, Sengupta U, Piccionello AP, Pace A, Campanella C, Bavisotto CC, Kayed R. INVESTIGATING THE POTENTIAL OF NOVEL CURCUMIN DERIVATIVES IN TARGETING AND MODULATING TOXIC TAU OLIGOMERIC STRAINS Alzheimer's & Dementia. 13: P1486. DOI: 10.1016/J.Jalz.2017.07.566 |
0.348 |
|
| 2017 |
Kayed R. TAU OLIGOMERIC STRAINS IN SYNUCLEINOPATHIES Alzheimer's & Dementia. 13: P1219-P1220. DOI: 10.1016/J.Jalz.2017.07.400 |
0.345 |
|
| 2017 |
Micci M, Krishnan B, Zhang W, Bishop E, Kernie S, Kayed R, Taglialatela G. SYNAPTIC RESILIENCE TO TAU AND AMYLOID BETA OLIGOMERS INDUCED BY NEURAL STEM CELL-DERIVED EXOSOMES Alzheimer's & Dementia. 13: P205. DOI: 10.1016/J.Jalz.2017.07.072 |
0.387 |
|
| 2017 |
Farmer K, Gerson JE, Kayed R. Oligomer Formation and Cross‐Seeding: The New Frontier Israel Journal of Chemistry. 57: 665-673. DOI: 10.1002/Ijch.201600103 |
0.542 |
|
| 2016 |
Troncone L, Luciani M, Coggins M, Wilker EH, Ho CY, Codispoti KE, Frosch MP, Kayed R, Del Monte F. Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer's Disease: Mind the Heart. Journal of the American College of Cardiology. 68: 2395-2407. PMID 27908343 DOI: 10.1016/J.Jacc.2016.08.073 |
0.431 |
|
| 2016 |
Bernini F, Malferrari D, Pignataro M, Bortolotti CA, Di Rocco G, Lancellotti L, Brigatti MF, Kayed R, Borsari M, Del Monte F, Castellini E. Pre-amyloid oligomers budding:a metastatic mechanism of proteotoxicity. Scientific Reports. 6: 35865. PMID 27775057 DOI: 10.1038/Srep35865 |
0.421 |
|
| 2016 |
Nilson AN, English KC, Gerson JE, Whittle TB, Crain CN, Xue J, Sengupta U, Castillo-Carranza DL, Zhang W, Gupta P, Kayed R. Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases. Journal of Alzheimer's Disease : Jad. PMID 27716675 DOI: 10.3233/Jad-160912 |
0.576 |
|
| 2016 |
Gerson JE, Mudher A, Kayed R. Potential mechanisms and implications for the formation of tau oligomeric strains. Critical Reviews in Biochemistry and Molecular Biology. 51: 482-496. PMID 27650389 DOI: 10.1080/10409238.2016.1226251 |
0.552 |
|
| 2016 |
Sengupta U, Nilson AN, Kayed R. The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy. Ebiomedicine. 6: 42-9. PMID 27211547 DOI: 10.1016/J.Ebiom.2016.03.035 |
0.532 |
|
| 2016 |
Gerson J, Kayed R. Therapeutic Approaches Targeting Pathological Tau Aggregates. Current Pharmaceutical Design. 22: 4028-39. PMID 27189598 DOI: 10.2174/1381612822666160518142226 |
0.56 |
|
| 2016 |
Gerson J, Castillo-Carranza DL, Sengupta U, Bodani R, Prough DS, DeWitt DS, Hawkins BE, Kayed R. Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice. Journal of Neurotrauma. PMID 26729399 DOI: 10.1089/Neu.2015.4262 |
0.474 |
|
| 2015 |
Kim Y, Choi H, Lee W, Park H, Kam TI, Hong SH, Nah J, Jung S, Shin B, Lee H, Choi TY, Choo H, Kim KK, Choi SY, Kayed R, et al. Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model. Neurobiology of Disease. 87: 19-28. PMID 26704708 DOI: 10.1016/J.Nbd.2015.12.006 |
0.52 |
|
| 2015 |
Lasagna-Reeves CA, Rousseaux MW, Guerrero-Munoz MJ, Vilanova-Velez L, Park J, See L, Jafar-Nejad P, Richman R, Orr HT, Kayed R, Zoghbi HY. Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes. Elife. 4. PMID 26673892 DOI: 10.7554/Elife.10891 |
0.722 |
|
| 2015 |
Bodani RU, Sengupta U, Castillo-Carranza DL, Guerrero-Muñoz MJ, Gerson JE, Rudra J, Kayed R. Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer's Disease. Acs Chemical Neuroscience. PMID 26448453 DOI: 10.1021/Acschemneuro.5B00231 |
0.573 |
|
| 2015 |
Violet M, Chauderlier A, Delattre L, Tardivel M, Chouala MS, Sultan A, Marciniak E, Humez S, Binder L, Kayed R, Lefebvre B, Bonnefoy E, Buée L, Galas MC. Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo. Neurobiology of Disease. 82: 540-51. PMID 26385829 DOI: 10.1016/J.Nbd.2015.09.003 |
0.473 |
|
| 2015 |
Deger JM, Gerson JE, Kayed R. The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration. Aging Cell. 14: 715-24. PMID 26053162 DOI: 10.1111/Acel.12359 |
0.579 |
|
| 2015 |
Lasagna-Reeves CA, Rousseaux MW, Guerrero-Muñoz MJ, Park J, Jafar-Nejad P, Richman R, Lu N, Sengupta U, Litvinchuk A, Orr HT, Kayed R, Zoghbi HY. A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1. Elife. 4. PMID 25988806 DOI: 10.7554/Elife.07558 |
0.773 |
|
| 2015 |
Castillo-Carranza DL, Guerrero-Muñoz MJ, Sengupta U, Hernandez C, Barrett AD, Dineley K, Kayed R. Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4857-68. PMID 25810517 DOI: 10.1523/Jneurosci.4989-14.2015 |
0.604 |
|
| 2015 |
Sengupta U, Guerrero-Muñoz MJ, Castillo-Carranza DL, Lasagna-Reeves CA, Gerson JE, Paulucci-Holthauzen AA, Krishnamurthy S, Farhed M, Jackson GR, Kayed R. Pathological Interface between Oligomeric Alpha-Synuclein and Tau in Synucleinopathies. Biological Psychiatry. PMID 25676491 DOI: 10.1016/J.Biopsych.2014.12.019 |
0.724 |
|
| 2015 |
Lasagna-Reeves CA, Rousseaux MW, Guerrero-Munoz MJ, Vilanova-Velez L, Park J, See L, Jafar-Nejad P, Richman R, Orr HT, Kayed R, Zoghbi HY. Author response: Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes Elife. DOI: 10.7554/Elife.10891.010 |
0.694 |
|
| 2015 |
Lasagna-Reeves CA, Rousseaux MW, Guerrero-Muñoz MJ, Park J, Jafar-Nejad P, Richman R, Lu N, Sengupta U, Litvinchuk A, Orr HT, Kayed R, Zoghbi HY. Author response: A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1 Elife. DOI: 10.7554/Elife.07558.025 |
0.699 |
|
| 2015 |
Lasagna-Reeves CA, Rousseaux MWC, Guerrero-Munoz MJ, Park J, Jafar-Nejad P, Richman R, Lu N, Sengupta U, Litvinchuk A, Orr HT, Kayed R, Zoghbi HY. A native interactor scaffolds and stabilizes toxic Ataxin-1 oligomers in SCA1 Elife. 4: 1-46. DOI: 10.7554/eLife.07558 |
0.691 |
|
| 2015 |
Meier SE, Bell MC, Lyons D, Lee T, Chen J, Abner EL, Wilcock DM, LeVine H, Zhu H, Kayed R, Abisambra JF. P1-007: Association of pathological tau with the ribosomal complex impairs protein synthesis Alzheimer's & Dementia. 11: P338-P338. DOI: 10.1016/J.Jalz.2015.06.203 |
0.391 |
|
| 2015 |
Sengupta U, Nilson AN, Kayed R. The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy Ebiomedicine. DOI: 10.1016/j.ebiom.2016.03.035 |
0.44 |
|
| 2014 |
Castillo-Carranza DL, Guerrero-Muñoz MJ, Kayed R. Immunotherapy for the treatment of Alzheimer's disease: amyloid-β or tau, which is the right target? Immunotargets and Therapy. 3: 19-28. PMID 27471697 DOI: 10.2147/ITT.S40131 |
0.485 |
|
| 2014 |
Guerrero-Muñoz MJ, Castillo-Carranza DL, Krishnamurthy S, Paulucci-Holthauzen AA, Sengupta U, Lasagna-Reeves CA, Ahmad Y, Jackson GR, Kayed R. Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease. Neurobiology of Disease. 71: 14-23. PMID 25134727 DOI: 10.1016/J.Nbd.2014.08.008 |
0.772 |
|
| 2014 |
Gerson JE, Castillo-Carranza DL, Kayed R. Advances in therapeutics for neurodegenerative tauopathies: moving toward the specific targeting of the most toxic tau species. Acs Chemical Neuroscience. 5: 752-69. PMID 25075869 DOI: 10.1021/Cn500143N |
0.548 |
|
| 2014 |
Gerson JE, Sengupta U, Lasagna-Reeves CA, Guerrero-Muñoz MJ, Troncoso J, Kayed R. Characterization of tau oligomeric seeds in progressive supranuclear palsy. Acta Neuropathologica Communications. 2: 73. PMID 24927818 DOI: 10.1186/2051-5960-2-73 |
0.768 |
|
| 2014 |
Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathologica Communications. 2: 56. PMID 24887264 DOI: 10.1186/2051-5960-2-56 |
0.792 |
|
| 2014 |
Castillo-Carranza DL, Sengupta U, Guerrero-Muñoz MJ, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4260-72. PMID 24647946 DOI: 10.1523/Jneurosci.3192-13.2014 |
0.769 |
|
| 2014 |
Castillo-Carranza DL, Gerson JE, Sengupta U, Guerrero-Muñoz MJ, Lasagna-Reeves CA, Kayed R. Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds. Journal of Alzheimer's Disease : Jad. 40: S97-S111. PMID 24603946 DOI: 10.3233/Jad-132477 |
0.777 |
|
| 2014 |
Guerrero-Muñoz MJ, Castillo-Carranza DL, Kayed R. Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins. Biochemical Pharmacology. 88: 468-78. PMID 24406245 DOI: 10.1016/J.Bcp.2013.12.023 |
0.517 |
|
| 2014 |
Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, Ambegaokar S, Kayed R, Jackson GR. TDP-43 Phosphorylation by casein kinase Iε promotes oligomerization and enhances toxicity in vivo. Human Molecular Genetics. 23: 1025-35. PMID 24105464 DOI: 10.1093/Hmg/Ddt498 |
0.438 |
|
| 2014 |
Abisambra J, Bodero M, Meier S, Neal M, Chen J, Bell M, Levine H, Kayed R, Zhu H, Nelson P. P2-071: PATHOLOGICAL TAU SPECIES ABROGATE NASCENT PROTEIN PRODUCTION BY ASSOCIATING WITH THE RIBOSOMAL COMPLEX: IMPLICATIONS OF A NOVEL TAU FUNCTION AND ITS PATHOGENIC LINK TO MEMORY IMPAIRMENT Alzheimer's & Dementia. 10: P495-P496. DOI: 10.1016/J.Jalz.2014.05.745 |
0.417 |
|
| 2014 |
Castillo-Carranza DL, Guerrero-Munoz MJ, Farhed M, Sengupta U, Krishnamurthy S, Kayed R. P1-122: OLIGOMERS OF A-SYNUCLEIN CROSS-SEED TAU AND EXTEND LIFETIME OF TAU TOXIC CONFORMATION Alzheimer's & Dementia. 10: P345-P345. DOI: 10.1016/J.Jalz.2014.05.359 |
0.464 |
|
| 2014 |
Sengupta U, Wilcock D, Kayed R. P4-215: TAU OLIGOMER-SPECIFIC ANTIBODIES IN INTRAVENOUS IMMUNOGLOBULINS (IVIGS): POTENTIAL THERAPEUTIC SIGNIFICANCE IN ALZHEIMER'S DISEASE AND OTHER NEURODEGENERATIVE TAUOPATHIES Alzheimer's & Dementia. 10: P866-P867. DOI: 10.1016/J.Jalz.2014.05.1733 |
0.511 |
|
| 2014 |
Guerrero-Munoz MJ, Castillo-Carranza DL, Krishnamurthy S, Kayed R. P3-066: TDP-43 HYBRID OLIGOMERS IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P651-P651. DOI: 10.1016/J.Jalz.2014.05.1154 |
0.438 |
|
| 2014 |
Gerson JE, Kayed R, Sengupta U. O5-04-01: DIFFERENT OLIGOMERIC TAU STRAINS ARE DETECTED WITH NOVEL ANTI-TAU OLIGOMER-SPECIFIC ANTIBODIES Alzheimer's & Dementia. 10: P297-P297. DOI: 10.1016/J.Jalz.2014.04.494 |
0.39 |
|
| 2014 |
Gerson JE, Castillo-Carranza DL, Sengupta U, Kayed R. O1-08-06: TAU OLIGOMERS DERIVED FROM TRAUMATIC BRAIN INJURY CAUSE TOXICITY AND COGNITIVE IMPAIRMENT IN HTAU MICE Alzheimer's & Dementia. 10: P146-P146. DOI: 10.1016/J.Jalz.2014.04.103 |
0.347 |
|
| 2013 |
Guerrero-Muñoz MJ, Castillo-Carranza DL, Sengupta U, White MA, Kayed R. Design of metastable β-sheet oligomers from natively unstructured peptide. Acs Chemical Neuroscience. 4: 1520-3. PMID 24106878 DOI: 10.1021/Cn4001395 |
0.459 |
|
| 2013 |
Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, ... ... Kayed R, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/Jci69003 |
0.572 |
|
| 2013 |
Gerson JE, Kayed R. Formation and propagation of tau oligomeric seeds. Frontiers in Neurology. 4: 93. PMID 23882255 DOI: 10.3389/Fneur.2013.00093 |
0.595 |
|
| 2013 |
Hawkins BE, Krishnamurthy S, Castillo-Carranza DL, Sengupta U, Prough DS, Jackson GR, DeWitt DS, Kayed R. Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies. The Journal of Biological Chemistry. 288: 17042-50. PMID 23632019 DOI: 10.1074/Jbc.M113.472746 |
0.385 |
|
| 2013 |
Kim HY, Sengupta U, Shao P, Guerrero-Muñoz MJ, Kayed R, Bai M. Alzheimer's disease imaging with a novel Tau targeted near infrared ratiometric probe. American Journal of Nuclear Medicine and Molecular Imaging. 3: 102-17. PMID 23526074 |
0.469 |
|
| 2013 |
Castillo-Carranza DL, Lasagna-Reeves CA, Kayed R. Tau aggregates as immunotherapeutic targets. Frontiers in Bioscience (Scholar Edition). 5: 426-38. PMID 23277060 DOI: 10.2741/S381 |
0.791 |
|
| 2013 |
Lasagna-Reeves CA, Clos AL, Castillo-Carranza D, Sengupta U, Guerrero-Muñoz M, Kelly B, Wagner R, Kayed R. Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity. Biochemical and Biophysical Research Communications. 430: 963-8. PMID 23261448 DOI: 10.1016/J.Bbrc.2012.11.130 |
0.727 |
|
| 2013 |
Wu JW, Herman M, Liu L, Simoes S, Acker CM, Figueroa H, Steinberg JI, Margittai M, Kayed R, Zurzolo C, Di Paolo G, Duff KE. Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. The Journal of Biological Chemistry. 288: 1856-70. PMID 23188818 DOI: 10.1074/Jbc.M112.394528 |
0.484 |
|
| 2013 |
Kayed R, Lasagna-Reeves CA. Molecular mechanisms of amyloid oligomers toxicity. Journal of Alzheimer's Disease : Jad. 33: S67-78. PMID 22531422 DOI: 10.3233/Jad-2012-129001 |
0.759 |
|
| 2013 |
Sengupta U, Portelius E, Castillo-Carranza D, Woltjer R, Galasko D, Jackson G, Blennow K, Kayed R. P4-356: Tau oligomers in CSF: A novel biomarker for the diagnosis and evaluation of treatment for Alzheimer's disease and tauopathies Alzheimer's & Dementia. 9: P862-P863. DOI: 10.1016/J.Jalz.2013.08.190 |
0.315 |
|
| 2013 |
Gerson J, Sengupta U, Lasagna Reeves C, Guerrero-Munoz M, Troncoso J, Jackson G, Kayed R. P4-334: Tau oligomers and annular protofibrils in progressive supranuclear palsy Alzheimer's & Dementia. 9: P854-P855. DOI: 10.1016/J.Jalz.2013.08.168 |
0.449 |
|
| 2013 |
Guerrero-Munoz M, Castillo-Carranza D, Lasagna-Reeves C, Sengupta U, Krishnamurthy S, Jackson G, Kayed R. P1-403: Formation of toxic oligomeric species from different proteins in Alzheimer's disease: Potential toxic interactions at the oligomer aggregation stage Alzheimer's & Dementia. 9: P305-P305. DOI: 10.1016/J.Jalz.2013.05.631 |
0.735 |
|
| 2013 |
Blair L, Nordhues B, Hill S, Scaglione KM, O'Leary J, Breydo L, Bo Z, Li P, Wang L, Cotman C, Paulson H, Muschol M, Uversky V, Klengel T, Binder E, ... Kayed R, et al. The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease Alzheimers & Dementia. 9: 173. DOI: 10.1016/J.Jalz.2013.05.279 |
0.504 |
|
| 2013 |
Castillo-Carranza D, Guerrero-Munoz M, Sengupta U, Krishnamurthy S, Gerson J, Dineley K, Jackson G, Kayed R. O2-08-02: Specific targeting of tau oligomeric seeds by passive immunization Alzheimer's & Dementia. 9: P330-P330. DOI: 10.1016/J.Jalz.2013.04.178 |
0.33 |
|
| 2013 |
Castillo-Carranza D, Guerrero-Munoz M, Sengupta U, Krishnamurthy S, Hernandez CM, Dineley K, Jackson G, Kayed R. O2-06-02: Reduction of tau oligomers by immunotherapy improves cognition in an Alzheimer's disease mouse model Alzheimer's & Dementia. 9: P325-P326. DOI: 10.1016/J.Jalz.2013.04.165 |
0.433 |
|
| 2012 |
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Scientific Reports. 2: 700. PMID 23050084 DOI: 10.1038/Srep00700 |
0.764 |
|
| 2012 |
Rosenmann H, Blum D, Kayed R, Ittner LM. Tau protein: function and pathology. International Journal of Alzheimer's Disease. 2012: 707482. PMID 22928147 DOI: 10.1155/2012/707482 |
0.588 |
|
| 2012 |
Rasool S, Albay R, Martinez-Coria H, Breydo L, Wu J, Milton S, Misra S, Tran A, Pensalfini A, Laferla F, Kayed R, Glabe CG. Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice. Molecular Neurodegeneration. 7: 37. PMID 22866920 DOI: 10.1186/1750-1326-7-37 |
0.363 |
|
| 2012 |
Castillo-Carranza DL, Zhang Y, Guerrero-Muñoz MJ, Kayed R, Rincon-Limas DE, Fernandez-Funez P. Differential activation of the ER stress factor XBP1 by oligomeric assemblies. Neurochemical Research. 37: 1707-17. PMID 22528838 DOI: 10.1007/S11064-012-0780-7 |
0.442 |
|
| 2012 |
Clos AL, Kayed R, Lasagna-Reeves CA. Association of skin with the pathogenesis and treatment of neurodegenerative amyloidosis. Frontiers in Neurology. 3: 5. PMID 22319507 DOI: 10.3389/Fneur.2012.00005 |
0.727 |
|
| 2012 |
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1946-59. PMID 22253473 DOI: 10.1096/Fj.11-199851 |
0.787 |
|
| 2012 |
Martin ZS, Neugebauer V, Dineley KT, Kayed R, Zhang W, Reese LC, Taglialatela G. α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases. Journal of Neurochemistry. 120: 440-52. PMID 22060133 DOI: 10.1111/J.1471-4159.2011.07576.X |
0.475 |
|
| 2012 |
Castillo-Carranza D, Lasagna-Reeves C, Guerrero-Munoz M, Sengupta U, Barrett A, Dineley K, Jackson G, Kayed R. O4-06-01: Specific clearance of tau oligomers by passive immunization Alzheimer's & Dementia. 8: P624-P625. DOI: 10.1016/J.Jalz.2012.05.1664 |
0.671 |
|
| 2011 |
Kayed R, Jackson GR, Estes DM, Barrett AD. Alzheimers disease: review of emerging treatment role for intravenous immunoglobulins. Journal of Central Nervous System Disease. 3: 67-73. PMID 23861639 DOI: 10.4137/JCNSD.S5018 |
0.391 |
|
| 2011 |
Lasagna-Reeves CA, Kayed R. Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains. Febs Letters. 585: 3052-7. PMID 21872592 DOI: 10.1016/J.Febslet.2011.08.027 |
0.758 |
|
| 2011 |
Clos AL, Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Jackson GR, Kelly B, Beachkofsky TM, Kayed R. Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis. The British Journal of Dermatology. 165: 1349-54. PMID 21729025 DOI: 10.1111/J.1365-2133.2011.10508.X |
0.757 |
|
| 2011 |
Clos AL, Lasagna-Reeves CA, Kelly B, Wagner R, Wilkerson M, Jackson GR, Kayed R. Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis. Journal of the American Academy of Dermatology. 65: 1023-31. PMID 21669474 DOI: 10.1016/J.Jaad.2010.09.735 |
0.756 |
|
| 2011 |
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Molecular Neurodegeneration. 6: 39. PMID 21645391 DOI: 10.1186/1750-1326-6-39 |
0.767 |
|
| 2011 |
Lasagna-Reeves CA, Castillo-Carranza DL, Jackson GR, Kayed R. Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies. Current Alzheimer Research. 8: 659-65. PMID 21605039 DOI: 10.2174/156720511796717177 |
0.79 |
|
| 2011 |
Lasagna-Reeves CA, Glabe CG, Kayed R. Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain. The Journal of Biological Chemistry. 286: 22122-30. PMID 21507938 DOI: 10.1074/Jbc.M111.236257 |
0.781 |
|
| 2011 |
Zepa L, Frenkel M, Belinson H, Kariv-Inbal Z, Kayed R, Masliah E, Michaelson DM. ApoE4-Driven Accumulation of Intraneuronal Oligomerized Aβ42 following Activation of the Amyloid Cascade In Vivo Is Mediated by a Gain of Function. International Journal of Alzheimer's Disease. 2011: 792070. PMID 21350674 DOI: 10.4061/2011/792070 |
0.415 |
|
| 2010 |
Kayed R, Canto I, Breydo L, Rasool S, Lukacsovich T, Wu J, Albay R, Pensalfini A, Yeung S, Head E, Marsh JL, Glabe C. Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers. Molecular Neurodegeneration. 5: 57. PMID 21144050 DOI: 10.1186/1750-1326-5-57 |
0.482 |
|
| 2010 |
Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. 49: 10039-41. PMID 21047142 DOI: 10.1021/Bi1016233 |
0.792 |
|
| 2010 |
Kayed R. Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease. Human Vaccines. 6: 931-5. PMID 20980799 DOI: 10.4161/Hv.6.11.12689 |
0.583 |
|
| 2010 |
Belinson H, Kariv-Inbal Z, Kayed R, Masliah E, Michaelson DM. Following activation of the amyloid cascade, apolipoprotein E4 drives the in vivo oligomerization of amyloid-β resulting in neurodegeneration. Journal of Alzheimer's Disease : Jad. 22: 959-70. PMID 20858958 DOI: 10.3233/Jad-2010-101008 |
0.54 |
|
| 2010 |
Lasagna-Reeves CA, Clos AL, Midoro-Hiriuti T, Goldblum RM, Jackson GR, Kayed R. Inhaled insulin forms toxic pulmonary amyloid aggregates. Endocrinology. 151: 4717-24. PMID 20685871 DOI: 10.1210/En.2010-0457 |
0.692 |
|
| 2010 |
Clos AL, Lasagna-Reeves CA, Wagner R, Kelly B, Jackson GR, Kayed R. Therapeutic removal of amyloid deposits in cutaneous amyloidosis by localised intra-lesional injections of anti-amyloid antibodies. Experimental Dermatology. 19: 904-11. PMID 20626464 DOI: 10.1111/J.1600-0625.2010.01121.X |
0.714 |
|
| 2010 |
Dineley KT, Kayed R, Neugebauer V, Fu Y, Zhang W, Reese LC, Taglialatela G. Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice. Journal of Neuroscience Research. 88: 2923-32. PMID 20544830 DOI: 10.1002/Jnr.22445 |
0.362 |
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| 2010 |
Head E, Pop V, Sarsoza F, Kayed R, Beckett TL, Studzinski CM, Tomic JL, Glabe CG, Murphy MP. Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines. Journal of Alzheimer's Disease : Jad. 20: 637-46. PMID 20164551 DOI: 10.3233/Jad-2010-1397 |
0.455 |
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| 2010 |
Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2442-53. PMID 20164328 DOI: 10.1523/Jneurosci.5038-09.2010 |
0.419 |
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| 2010 |
Barrett AD, Kayed R, Jackson GR, Cunningham KA. New vaccine development for chronic brain disease. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 354. PMID 20010720 DOI: 10.1038/Npp.2009.147 |
0.382 |
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| 2010 |
Isas JM, Luibl V, Johnson LV, Kayed R, Wetzel R, Glabe CG, Langen R, Chen J. Soluble and mature amyloid fibrils in drusen deposits. Investigative Ophthalmology & Visual Science. 51: 1304-10. PMID 19892876 DOI: 10.1167/Iovs.09-4207 |
0.483 |
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| 2009 |
Kokubo H, Kayed R, Glabe CG, Staufenbiel M, Saido TC, Iwata N, Yamaguchi H. Amyloid Beta annular protofibrils in cell processes and synapses accumulate with aging and Alzheimer-associated genetic modification. International Journal of Alzheimer's Disease. 2009. PMID 20798763 DOI: 10.4061/2009/689285 |
0.478 |
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| 2009 |
Mina EW, Lasagna-Reeves C, Glabe CG, Kayed R. Poloxamer 188 copolymer membrane sealant rescues toxicity of amyloid oligomers in vitro. Journal of Molecular Biology. 391: 577-85. PMID 19524592 DOI: 10.1016/J.Jmb.2009.06.024 |
0.711 |
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| 2009 |
Kayed R, Jackson GR. Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders. Current Opinion in Immunology. 21: 359-63. PMID 19482462 DOI: 10.1016/J.Coi.2009.05.001 |
0.529 |
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| 2009 |
Yanamandra K, Alexeyev O, Zamotin V, Srivastava V, Shchukarev A, Brorsson AC, Tartaglia GG, Vogl T, Kayed R, Wingsle G, Olsson J, Dobson CM, Bergh A, Elgh F, Morozova-Roche LA. Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. Plos One. 4: e5562. PMID 19440546 DOI: 10.1371/Journal.Pone.0005562 |
0.39 |
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| 2009 |
Sarsoza F, Saing T, Kayed R, Dahlin R, Dick M, Broadwater-Hollifield C, Mobley S, Lott I, Doran E, Gillen D, Anderson-Bergman C, Cribbs DH, Glabe C, Head E. A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain. Acta Neuropathologica. 118: 505-17. PMID 19360426 DOI: 10.1007/S00401-009-0530-3 |
0.537 |
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| 2009 |
Kayed R, Pensalfini A, Margol L, Sokolov Y, Sarsoza F, Head E, Hall J, Glabe C. Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer. The Journal of Biological Chemistry. 284: 4230-7. PMID 19098006 DOI: 10.1074/Jbc.M808591200 |
0.515 |
|
| 2009 |
Reese LC, Zhang W, Kayed R, Taglialatela G. P4-225: Induction of calcineurin activity and signaling by oligomeric amyloid-beta isolated from Alzheimer brains Alzheimer's & Dementia. 5: P496-P496. DOI: 10.1016/J.Jalz.2009.04.691 |
0.396 |
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| 2008 |
Shin TM, Isas JM, Hsieh CL, Kayed R, Glabe CG, Langen R, Chen J. Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin. Molecular Neurodegeneration. 3: 16. PMID 18939994 DOI: 10.1186/1750-1326-3-16 |
0.591 |
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| 2008 |
Reese LC, Zhang W, Dineley KT, Kayed R, Taglialatela G. Selective induction of calcineurin activity and signaling by oligomeric amyloid beta. Aging Cell. 7: 824-35. PMID 18782350 DOI: 10.1111/J.1474-9726.2008.00434.X |
0.497 |
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| 2008 |
Bacher M, Dodel R, Aljabari B, Keyvani K, Marambaud P, Kayed R, Glabe C, Goertz N, Hoppmann A, Sachser N, Klotsche J, Schnell S, Lewejohann L, Al-Abed Y. CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease. The Journal of Experimental Medicine. 205: 1593-9. PMID 18573905 DOI: 10.1084/Jem.20060467 |
0.528 |
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| 2008 |
Taglialatela G, Reese LC, Zhang W, Dineley KT, Kayed R. P4-264: Oligomers from different disease-related amyloid proteins induce common neurodysfunctional events Alzheimer's & Dementia. 4: T748-T749. DOI: 10.1016/J.Jalz.2008.05.2333 |
0.455 |
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| 2008 |
Bacher M, Dodel R, Aljabari B, Keyvani K, Marambaud P, Kayed R, Glabe C, Goertz N, Lewejohann L, Sachser N, Klotsche J, Al-Abed Y. P2-291: Administration of CNI-1493 inhibits Aβ accumulation, Amyloid plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1367 |
0.509 |
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| 2007 |
Yoshiike Y, Kayed R, Milton SC, Takashima A, Glabe CG. Pore-forming proteins share structural and functional homology with amyloid oligomers. Neuromolecular Medicine. 9: 270-5. PMID 17914185 DOI: 10.1007/S12017-007-0003-6 |
0.412 |
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| 2007 |
Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG. Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Molecular Neurodegeneration. 2: 18. PMID 17897471 DOI: 10.1186/1750-1326-2-18 |
0.547 |
|
| 2007 |
Necula M, Breydo L, Milton S, Kayed R, van der Veer WE, Tone P, Glabe CG. Methylene blue inhibits amyloid Abeta oligomerization by promoting fibrillization. Biochemistry. 46: 8850-60. PMID 17595112 DOI: 10.1021/Bi700411K |
0.504 |
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| 2007 |
Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J. Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 104: 5995-6000. PMID 17389375 DOI: 10.1073/Pnas.0609202104 |
0.324 |
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| 2007 |
Lin CY, Gurlo T, Kayed R, Butler AE, Haataja L, Glabe CG, Butler PC. Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice. Diabetes. 56: 1324-32. PMID 17353506 DOI: 10.2337/Db06-1579 |
0.369 |
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| 2007 |
Necula M, Kayed R, Milton S, Glabe CG. Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. The Journal of Biological Chemistry. 282: 10311-24. PMID 17284452 DOI: 10.1074/Jbc.M608207200 |
0.483 |
|
| 2007 |
Wirths O, Weis J, Kayed R, Saido TC, Bayer TA. Age-dependent axonal degeneration in an Alzheimer mouse model. Neurobiology of Aging. 28: 1689-99. PMID 16963164 DOI: 10.1016/J.Neurobiolaging.2006.07.021 |
0.357 |
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| 2007 |
Zhou J, Fonseca MI, Billings-Luhr L, Kayed R, Glabe CG, LaFerla F, Tenner AJ. Effect of immunization with the oligomeric form of the Aβ peptide: Reduction of senile plaque area, decreased complement C3 deposition and synthesis, and decline in behavioral function in a murine model of Alzheimer's disease Molecular Immunology. 44: 264-265. DOI: 10.1016/J.Molimm.2006.07.277 |
0.457 |
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| 2006 |
Sokolov Y, Kozak JA, Kayed R, Chanturiya A, Glabe C, Hall JE. Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure. The Journal of General Physiology. 128: 637-47. PMID 17101816 DOI: 10.1085/Jgp.200609533 |
0.392 |
|
| 2006 |
Kayed R, Glabe CG. Conformation-dependent anti-amyloid oligomer antibodies. Methods in Enzymology. 413: 326-44. PMID 17046404 DOI: 10.1016/S0076-6879(06)13017-7 |
0.565 |
|
| 2006 |
Meier JJ, Kayed R, Lin CY, Gurlo T, Haataja L, Jayasinghe S, Langen R, Glabe CG, Butler PC. Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP. American Journal of Physiology. Endocrinology and Metabolism. 291: E1317-24. PMID 16849627 DOI: 10.1152/Ajpendo.00082.2006 |
0.409 |
|
| 2006 |
Chong YH, Shin YJ, Lee EO, Kayed R, Glabe CG, Tenner AJ. ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. The Journal of Biological Chemistry. 281: 20315-25. PMID 16714296 DOI: 10.1074/Jbc.M601016200 |
0.469 |
|
| 2006 |
Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH. A specific amyloid-beta protein assembly in the brain impairs memory. Nature. 440: 352-7. PMID 16541076 DOI: 10.1038/Nature04533 |
0.47 |
|
| 2006 |
Head E, Barrett EG, Murphy MP, Das P, Nistor M, Sarsoza F, Glabe CC, Kayed R, Milton S, Vasilevko V, Milgram NW, Agadjanyan MG, Cribbs DH, Cotman CW. Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta. Vaccine. 24: 2824-34. PMID 16460841 DOI: 10.1016/J.Vaccine.2005.12.058 |
0.406 |
|
| 2006 |
Luibl V, Isas JM, Kayed R, Glabe CG, Langen R, Chen J. Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. The Journal of Clinical Investigation. 116: 378-85. PMID 16453022 DOI: 10.1172/Jci25843 |
0.53 |
|
| 2006 |
Glabe CG, Kayed R. Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis. Neurology. 66: S74-8. PMID 16432151 DOI: 10.1212/01.Wnl.0000192103.24796.42 |
0.503 |
|
| 2006 |
Al-Lahham R, Bittar A, Montalbano M, Carretero-Murillo M, McAllen S, Bhatt N, Ellsworth A, Kayed R. O5-05-06: EVALUATING TAU OLIGOMERS PASSIVE IMMUNOTHERAPY USING AGED TRANSGENIC ANIMALS OF TAUOPATHY Alzheimer's & Dementia. 14: P1657-P1657. DOI: 10.1016/J.Jalz.2018.06.3024 |
0.359 |
|
| 2006 |
Gerson JE, Farmer K, Sengupta U, Carretero-Murillo M, McAllen S, Bhatt N, Ellsworth A, Ha Y, Zhang W, Kayed R. O2-02-06: PROPAGATION AND DIVERSE EFFECTS OF DISEASE-SPECIFIC PRION-LIKE TAU OLIGOMERIC STRAINS Alzheimer's & Dementia. 14: P612-P612. DOI: 10.1016/J.Jalz.2018.06.2650 |
0.39 |
|
| 2006 |
Taglialatela G, Micci M, Krishnan B, Kernie S, Widen S, Tunnel K, Kayed R. O2-01-03: SELECTED MICRO RNAS FROM NEURAL STEM CELL-DERIVED EXOSOMES INCREASE SYNAPTIC RESILIENCE TO TAU AND Aβ OLIGOMERS Alzheimer's & Dementia. 14: P609-P609. DOI: 10.1016/J.Jalz.2018.06.2641 |
0.343 |
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| 2006 |
Taglialatela G, Krishnan B, Kayed R, Micci M. P3-170: INCREASED SYNAPTIC SENSITIVITY TO Aβ AND TAU OLIGOMERS IN THE AGING CNS AS A FUNCTION OF DECREASING NEURAL STEM CELLS Alzheimer's & Dementia. 14: P1133-P1133. DOI: 10.1016/J.Jalz.2018.06.1528 |
0.375 |
|
| 2006 |
Krishnan B, Kayed R, Taglialatela G. P3-167: INHIBITION OF PHOSPHOLIPASE D1 AS A THERAPEUTIC IN AD-RELATED MEMORY DEFICITS Alzheimer's & Dementia. 14: P1131-P1132. DOI: 10.1016/J.Jalz.2018.06.1525 |
0.313 |
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| 2006 |
Ruan Z, DeLeo AM, Yoshii-Kitahara A, Ikezu S, Kayed R, Golantla S, Gendelman HE, Ikezu T. P1-025: EXOSOMES CONTAINING SPECIFIC TAU OLIGOMER FORMATIONS ACCELERATE PATHOLOGICAL TAU PHOSPHORYLATION IN C57BL/6 MICE Alzheimer's & Dementia. 14: P275-P275. DOI: 10.1016/J.Jalz.2018.06.026 |
0.467 |
|
| 2006 |
Bittar A, Hassan T, Bhatt N, McAllen S, Carretero-Murillo M, Ellsworth A, Kayed R. P1-021: TOXICITY AND PROPAGATION OF TBI BRAIN-DERIVED SOLUBLE TAU STRAINS Alzheimer's & Dementia. 14: P273-P273. DOI: 10.1016/J.Jalz.2018.06.022 |
0.361 |
|
| 2006 |
Bacher M, Dodel R, Aljabari B, Keyvani K, Marambaud P, Kayed R, Glabe C, Goertz N, Schnell S, Al-Abed Y. P1-100: CNI-1493 inhibits Aβ production and prevents plaque formation in an animal model of Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.475 |
0.436 |
|
| 2006 |
Wirths O, Weis J, Kayed R, Saido TC, Bayer TA. P1-028: Axonopathy in APP/PS1 transgenic mouse models of Alzheimer's disease Alzheimer's & Dementia. 2: S102-S102. DOI: 10.1016/J.Jalz.2006.05.403 |
0.457 |
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| 2005 |
Zhou J, Fonseca MI, Kayed R, Hernandez I, Webster SD, Yazan O, Cribbs DH, Glabe CG, Tenner AJ. Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease. Journal of Neuroinflammation. 2: 28. PMID 16332263 DOI: 10.1186/1742-2094-2-28 |
0.514 |
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| 2005 |
Sanbe A, Osinska H, Villa C, Gulick J, Klevitsky R, Glabe CG, Kayed R, Robbins J. Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 102: 13592-7. PMID 16155124 DOI: 10.1073/Pnas.0503324102 |
0.5 |
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| 2005 |
Kokubo H, Kayed R, Glabe CG, Saido TC, Iwata N, Helms JB, Yamaguchi H. Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain. Brain Research. 1045: 224-8. PMID 15910781 DOI: 10.1016/J.Brainres.2005.03.017 |
0.392 |
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| 2005 |
Kranenburg O, Bouma B, Gent YY, Aarsman CJ, Kayed R, Posthuma G, Schiks B, Voest EE, Gebbink MF. Beta-amyloid (Abeta) causes detachment of N1E-115 neuroblastoma cells by acting as a scaffold for cell-associated plasminogen activation. Molecular and Cellular Neurosciences. 28: 496-508. PMID 15737740 DOI: 10.1016/J.Mcn.2004.11.001 |
0.497 |
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| 2005 |
Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG. Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. The Journal of Biological Chemistry. 280: 17294-300. PMID 15722360 DOI: 10.1074/Jbc.M500997200 |
0.376 |
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| 2005 |
Kokubo H, Kayed R, Glabe CG, Yamaguchi H. Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain. Brain Research. 1031: 222-8. PMID 15649447 DOI: 10.1016/J.Brainres.2004.10.041 |
0.492 |
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| 2005 |
Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. The Journal of Biological Chemistry. 280: 5892-901. PMID 15590663 DOI: 10.1074/Jbc.M404751200 |
0.531 |
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| 2004 |
Kayed R, Sokolov Y, Edmonds B, McIntire TM, Milton SC, Hall JE, Glabe CG. Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. The Journal of Biological Chemistry. 279: 46363-6. PMID 15385542 DOI: 10.1074/Jbc.C400260200 |
0.522 |
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| 2004 |
Sanbe A, Osinska H, Saffitz JE, Glabe CG, Kayed R, Maloyan A, Robbins J. Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 10132-6. PMID 15220483 DOI: 10.1073/Pnas.0401900101 |
0.488 |
|
| 2004 |
Kayed R, Glabe C. P1-172 Annular protofibrils, formation, stability and toxicity: new insights into the pore-like mechanism for amyloid toxicity Neurobiology of Aging. 25: S144. DOI: 10.1016/S0197-4580(04)80485-8 |
0.44 |
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| 2004 |
Glabe C, Kayed R, Sokolov Y, Hall J. O4-02-02 Common structure and mechanism of soluble amyloid oligomer pathogenesis in degenerative diseases Neurobiology of Aging. 25: S75-S76. DOI: 10.1016/S0197-4580(04)80257-4 |
0.453 |
|
| 2003 |
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 39: 409-21. PMID 12895417 DOI: 10.1016/S0896-6273(03)00434-3 |
0.505 |
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| 2003 |
Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science (New York, N.Y.). 300: 486-9. PMID 12702875 DOI: 10.1126/Science.1079469 |
0.571 |
|
| 2002 |
Török M, Milton S, Kayed R, Wu P, McIntire T, Glabe CG, Langen R. Structural and dynamic features of Alzheimer's Abeta peptide in amyloid fibrils studied by site-directed spin labeling. The Journal of Biological Chemistry. 277: 40810-5. PMID 12181315 DOI: 10.1074/Jbc.M205659200 |
0.47 |
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| 2002 |
Soreghan B, Pike C, Kayed R, Tian W, Milton S, Cotman C, Glabe CG. The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties. Neuromolecular Medicine. 1: 81-94. PMID 12025818 DOI: 10.1385/Nmm:1:1:81 |
0.47 |
|
| 1999 |
Kapurniotu A, Kayed R, Taylor JW, Voelter W. Rational design, conformational studies and bioactivity of highly potent conformationally constrained calcitonin analogues Febs Journal. 265: 606-618. PMID 10504392 DOI: 10.1046/J.1432-1327.1999.00708.X |
0.304 |
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| 1999 |
Kayed R, Bernhagen J, Greenfield N, Sweimeh K, Brunner H, Voelter W, Kapurniotu A. Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro Journal of Molecular Biology. 287: 781-796. PMID 10191146 DOI: 10.1006/Jmbi.1999.2646 |
0.525 |
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