| Year |
Citation |
Score |
| 2024 |
Xiao Y, Pan Y, Xiao J, Cummins TR. Molecular determinants of resurgent sodium currents mediated by Navβ4 peptide and A-type FHFs. Frontiers in Molecular Neuroscience. 17: 1433981. PMID 39416265 DOI: 10.3389/fnmol.2024.1433981 |
0.414 |
|
| 2024 |
Shin SM, Itson-Zoske B, Fan F, Xiao Y, Qiu C, Cummins TR, Hogan QH, Yu H. Peripherally targeted analgesia via AAV-mediated sensory neuron-specific inhibition of multiple pronociceptive sodium channels. The Journal of Clinical Investigation. PMID 38722683 DOI: 10.1172/JCI170813 |
0.49 |
|
| 2022 |
Zybura AS, Sahoo FK, Hudmon A, Cummins TR. CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav1.6 Channels and Reduces Neuronal Excitability. Cells. 11. PMID 35805192 DOI: 10.3390/cells11132108 |
0.508 |
|
| 2022 |
George K, Lopez-Mateos D, Abd El-Aziz TM, Xiao Y, Kline J, Bao H, Raza S, Stockand JD, Cummins TR, Fornelli L, Rowe MP, Yarov-Yarovoy V, Rowe AH. Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits Na1.8 via Interactions With the DI Voltage Sensor and DII Pore Module. Frontiers in Pharmacology. 13: 846992. PMID 35662692 DOI: 10.3389/fphar.2022.846992 |
0.436 |
|
| 2022 |
Xiao Y, Theile JW, Zybura A, Pan Y, Lin Z, Cummins TR. A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels. Elife. 11. PMID 35441593 DOI: 10.7554/eLife.77558 |
0.57 |
|
| 2021 |
Abd El-Aziz TM, Xiao Y, Kline J, Gridley H, Heaston A, Linse KD, Ward MJ, Rokyta DR, Stockand JD, Cummins TR, Fornelli L, Rowe AH. Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling. Toxins. 13. PMID 34357973 DOI: 10.3390/toxins13070501 |
0.43 |
|
| 2021 |
Zybura A, Hudmon A, Cummins TR. Distinctive Properties and Powerful Neuromodulation of Na1.6 Sodium Channels Regulates Neuronal Excitability. Cells. 10. PMID 34202119 DOI: 10.3390/cells10071595 |
0.515 |
|
| 2020 |
Zybura AS, Baucum AJ, Rush AM, Cummins TR, Hudmon A. CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability. The Journal of Biological Chemistry. PMID 32611770 DOI: 10.1074/Jbc.Ra120.014062 |
0.502 |
|
| 2020 |
VanderWall KB, Huang KC, Pan Y, Lavekar SS, Fligor CM, Allsop AR, Lentsch KA, Dang P, Zhang C, Tseng HC, Cummins TR, Meyer JS. Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids. Stem Cell Reports. PMID 32531194 DOI: 10.1016/J.Stemcr.2020.05.009 |
0.304 |
|
| 2020 |
Mason ER, Cummins TR. Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967. International Journal of Molecular Sciences. 21. PMID 32244818 DOI: 10.3390/ijms21072454 |
0.422 |
|
| 2020 |
Pan Y, Xiao Y, Pei Z, Cummins TR. S-palmitoylation of the sodium channel Nav1.6 regulates its activity and neuronal excitability. The Journal of Biological Chemistry. PMID 32161114 DOI: 10.1074/jbc.RA119.012423 |
0.423 |
|
| 2020 |
Cunningham G, Cantor E, Wu X, Shen F, Jiang G, Philips S, Bales C, Xiao Y, Cummins TR, Fehrenbacher JC, Schneider BP. Abstract P5-07-09: Modeling taxane-induced peripheral neuropathy ex vivo using patient-derived neurons Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-07-09 |
0.405 |
|
| 2019 |
Pan Y, Cummins TR. Distinct functional alterations in SCN8A epilepsy mutant channels. The Journal of Physiology. PMID 31715021 DOI: 10.1113/Jp278952 |
0.558 |
|
| 2019 |
Mason ER, Wu F, Patel RR, Xiao Y, Cannon SC, Cummins TR. Resurgent and Gating Pore Currents Induced by de novo Epilepsy Mutations. Eneuro. PMID 31558572 DOI: 10.1523/ENEURO.0141-19.2019 |
0.807 |
|
| 2019 |
Bansal R, Engle SE, Antonellis PJ, Whitehouse LS, Baucum AJ, Cummins TR, Reiter JF, Berbari NF. Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures. Frontiers in Cellular Neuroscience. 13: 266. PMID 31249512 DOI: 10.3389/Fncel.2019.00266 |
0.357 |
|
| 2019 |
Wu B, McDermott J, Krajewski J, Knopp KL, Nisenbaum E, Cummins T, Tan Z. [EXPRESS] Extracellular signal-regulated kinases mediate the enhancing effects of inflammatory mediators on resurgent currents in dorsal root ganglion neurons. Molecular Pain. 1744806919837104. PMID 30803321 DOI: 10.1177/1744806919837104 |
0.452 |
|
| 2019 |
Xiao Y, Barbosa C, Pei Z, Xie W, Strong JA, Zhang JM, Cummins TR. Increased resurgent sodium currents in Nav1.8 contribute to nociceptive sensory neuron hyperexcitability associated with peripheral neuropathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30617209 DOI: 10.1523/Jneurosci.0468-18.2018 |
0.656 |
|
| 2017 |
Shi W, Zeng Y, Zhu C, Xiao Y, Cummins TR, Hou J, Baker LA. Characterization of Membrane Patch-Ion Channel Probes for Scanning Ion Conductance Microscopy. Small (Weinheim An Der Bergstrasse, Germany). PMID 29226633 DOI: 10.1002/smll.201702945 |
0.353 |
|
| 2017 |
Pei Z, Pan Y, Cummins TR. Posttranslational Modification of Sodium Channels. Handbook of Experimental Pharmacology. PMID 29071507 DOI: 10.1007/164_2017_69 |
0.359 |
|
| 2016 |
Barbosa C, Xiao Y, Johnson AJ, Xie W, Strong JA, Zhang JM, Cummins TR. FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons. Pflugers Archiv : European Journal of Physiology. PMID 27999940 DOI: 10.1007/S00424-016-1911-9 |
0.594 |
|
| 2016 |
Shi W, Zeng Y, Zhou L, Xiao Y, Cummins TR, Baker LA. Membrane patches as ion channel probes for scanning ion conductance microscopy. Faraday Discussions. PMID 27711908 DOI: 10.1039/c6fd00133e |
0.367 |
|
| 2016 |
Barbosa C, Cummins TR. Unusual Voltage-Gated Sodium Currents as Targets for Pain. Current Topics in Membranes. 78: 599-638. PMID 27586296 DOI: 10.1016/Bs.Ctm.2015.12.005 |
0.638 |
|
| 2016 |
Pei Z, Xiao Y, Meng J, Hudmon A, Cummins TR. Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation. Nature Communications. 7: 12035. PMID 27337590 DOI: 10.1038/Ncomms12035 |
0.501 |
|
| 2016 |
Patel RR, Barbosa C, Brustovetsky T, Brustovetsky N, Cummins TR. Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. Brain : a Journal of Neurology. PMID 27267376 DOI: 10.1093/Brain/Aww129 |
0.846 |
|
| 2015 |
Xie W, Tan ZY, Barbosa C, Strong JA, Cummins TR, Zhang JM. Upregulation of the sodium channel NaVβ4 subunit and its contributions to mechanical hypersensitivity and neuronal hyperexcitability in a rat model of radicular pain induced by local DRG inflammation. Pain. PMID 26785322 DOI: 10.1097/J.Pain.0000000000000453 |
0.581 |
|
| 2015 |
Barbosa C, Tan ZY, Wang R, Xie W, Strong JA, Patel RR, Vasko MR, Zhang JM, Cummins TR. Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons. Molecular Pain. 11: 60. PMID 26408173 DOI: 10.1186/S12990-015-0063-9 |
0.838 |
|
| 2015 |
Patel RR, Barbosa C, Xiao Y, Cummins TR. Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction. Plos One. 10: e0133485. PMID 26182346 DOI: 10.1371/Journal.Pone.0133485 |
0.834 |
|
| 2015 |
Torregrosa R, Yang XF, Dustrude ET, Cummins TR, Khanna R, Kohn H. Chimeric derivatives of functionalized amino acids and α-aminoamides: Compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels. Bioorganic & Medicinal Chemistry. 23: 3655-66. PMID 25922183 DOI: 10.1016/J.Bmc.2015.04.014 |
0.435 |
|
| 2014 |
Tan ZY, Priest BT, Krajewski JL, Knopp KL, Nisenbaum ES, Cummins TR. Protein kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III-IV linker. Febs Letters. 588: 3964-9. PMID 25240195 DOI: 10.1016/J.Febslet.2014.09.011 |
0.512 |
|
| 2014 |
Lee H, Park KD, Torregrosa R, Yang XF, Dustrude ET, Wang Y, Wilson SM, Barbosa C, Xiao Y, Cummins TR, Khanna R, Kohn H. Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels. Journal of Medicinal Chemistry. 57: 6165-82. PMID 25004277 DOI: 10.1021/Jm500707R |
0.388 |
|
| 2014 |
Xiao Y, Blumenthal K, Cummins TR. Gating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins. Molecular Pharmacology. 86: 159-67. PMID 24898004 DOI: 10.1124/Mol.114.092338 |
0.517 |
|
| 2014 |
Tan ZY, Piekarz AD, Priest BT, Knopp KL, Krajewski JL, McDermott JS, Nisenbaum ES, Cummins TR. Tetrodotoxin-resistant sodium channels in sensory neurons generate slow resurgent currents that are enhanced by inflammatory mediators. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7190-7. PMID 24849353 DOI: 10.1523/Jneurosci.5011-13.2014 |
0.853 |
|
| 2014 |
Chen X, Sun W, Gianaris NG, Riley AM, Cummins TR, Fehrenbacher JC, Obukhov AG. Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel. The Journal of Biological Chemistry. 289: 9600-10. PMID 24569998 DOI: 10.1074/Jbc.M113.536862 |
0.506 |
|
| 2014 |
Tan Z, Piekarz A, Priest B, Knopp K, Krajewski J, McDermott J, Nisenbaum E, Cummins T. (344) Tetrodotoxin-resistant sodium channels in sensory neurons generate slow resurgent currents that are enhanced by inflammatory mediators The Journal of Pain. 15. DOI: 10.1016/J.Jpain.2014.01.254 |
0.575 |
|
| 2013 |
Rowe AH, Xiao Y, Rowe MP, Cummins TR, Zakon HH. Voltage-gated sodium channel in grasshopper mice defends against bark scorpion toxin. Science (New York, N.Y.). 342: 441-6. PMID 24159039 DOI: 10.1126/Science.1236451 |
0.478 |
|
| 2013 |
Reddy Chichili VP, Xiao Y, Seetharaman J, Cummins TR, Sivaraman J. Structural basis for the modulation of the neuronal voltage-gated sodium channel NaV1.6 by calmodulin. Scientific Reports. 3: 2435. PMID 23942337 DOI: 10.1038/Srep02435 |
0.493 |
|
| 2012 |
King AM, Yang XF, Wang Y, Dustrude ET, Barbosa C, Due MR, Piekarz AD, Wilson SM, White FA, Salomé C, Cummins TR, Khanna R, Kohn H. Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation. Acs Chemical Neuroscience. 3: 1037-49. PMID 23259039 DOI: 10.1021/Cn300129D |
0.825 |
|
| 2012 |
Song W, Xiao Y, Chen H, Ashpole NM, Piekarz AD, Ma P, Hudmon A, Cummins TR, Shou W. The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity. The Journal of Physiology. 590: 5123-39. PMID 22826127 DOI: 10.1113/Jphysiol.2012.235374 |
0.847 |
|
| 2012 |
Brittain MK, Brustovetsky T, Brittain JM, Khanna R, Cummins TR, Brustovetsky N. Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons. Neuropharmacology. 63: 974-82. PMID 22820271 DOI: 10.1016/J.Neuropharm.2012.07.012 |
0.382 |
|
| 2012 |
Fu LY, Cummins TR, Moczydlowski EG. Sensitivity of cloned muscle, heart and neuronal voltage-gated sodium channels to block by polyamines: a possible basis for modulation of excitability in vivo. Channels (Austin, Tex.). 6: 41-9. PMID 22522923 DOI: 10.4161/Chan.19001 |
0.603 |
|
| 2012 |
Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A. Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites. The Journal of Biological Chemistry. 287: 19856-69. PMID 22514276 DOI: 10.1074/Jbc.M111.322537 |
0.361 |
|
| 2012 |
Ashpole NM, Song W, Brustovetsky T, Engleman EA, Brustovetsky N, Cummins TR, Hudmon A. Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. The Journal of Biological Chemistry. 287: 8495-506. PMID 22253441 DOI: 10.1074/Jbc.M111.323915 |
0.383 |
|
| 2012 |
Brittain MK, Brustovetsky T, Sheets PL, Brittain JM, Khanna R, Cummins TR, Brustovetsky N. Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger. Neurobiology of Disease. 46: 109-17. PMID 22249110 DOI: 10.1016/J.Nbd.2011.12.051 |
0.732 |
|
| 2011 |
Theile JW, Cummins TR. Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes. Frontiers in Pharmacology. 2: 54. PMID 22007172 DOI: 10.3389/Fphar.2011.00054 |
0.583 |
|
| 2011 |
Rowe AH, Xiao Y, Scales J, Linse KD, Rowe MP, Cummins TR, Zakon HH. Isolation and characterization of CvIV4: a pain inducing α-scorpion toxin. Plos One. 6: e23520. PMID 21887265 DOI: 10.1371/Journal.Pone.0023520 |
0.527 |
|
| 2011 |
Koehler KR, Tropel P, Theile JW, Kondo T, Cummins TR, Viville S, Hashino E. Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells. Bmc Neuroscience. 12: 82. PMID 21831300 DOI: 10.1186/1471-2202-12-82 |
0.359 |
|
| 2011 |
Wilson SM, Brittain JM, Piekarz AD, Ballard CJ, Ripsch MS, Cummins TR, Hurley JH, Khanna M, Hammes NM, Samuels BC, White FA, Khanna R. Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex. Channels (Austin, Tex.). 5: 449-56. PMID 21829088 DOI: 10.4161/Chan.5.5.17363 |
0.85 |
|
| 2011 |
Theile JW, Cummins TR. Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide. Molecular Pharmacology. 80: 724-34. PMID 21788423 DOI: 10.1124/Mol.111.072751 |
0.655 |
|
| 2011 |
Xiao Y, Jackson JO, Liang S, Cummins TR. Common molecular determinants of tarantula huwentoxin-IV inhibition of Na+ channel voltage sensors in domains II and IV. The Journal of Biological Chemistry. 286: 27301-10. PMID 21659528 DOI: 10.1074/Jbc.M111.246876 |
0.412 |
|
| 2011 |
Sheets PL, Jarecki BW, Cummins TR. Lidocaine reduces the transition to slow inactivation in Na(v)1.7 voltage-gated sodium channels. British Journal of Pharmacology. 164: 719-30. PMID 21232038 DOI: 10.1111/J.1476-5381.2011.01209.X |
0.858 |
|
| 2011 |
Theile JW, Jarecki BW, Piekarz AD, Cummins TR. Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navbeta4 peptide-mediated resurgent sodium currents. The Journal of Physiology. 589: 597-608. PMID 21115638 DOI: 10.1113/Jphysiol.2010.200915 |
0.808 |
|
| 2011 |
Brustovetsky T, Brittain MK, Sheets PL, Cummins TR, Pinelis V, Brustovetsky N. KB-R7943, an inhibitor of the reverse Na+ /Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I. British Journal of Pharmacology. 162: 255-70. PMID 20883473 DOI: 10.1111/J.1476-5381.2010.01054.X |
0.7 |
|
| 2010 |
Xiao Y, Blumenthal K, Jackson JO, Liang S, Cummins TR. The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation. Molecular Pharmacology. 78: 1124-34. PMID 20855463 DOI: 10.1124/Mol.110.066332 |
0.452 |
|
| 2010 |
Wang Y, Brittain JM, Jarecki BW, Park KD, Wilson SM, Wang B, Hale R, Meroueh SO, Cummins TR, Khanna R. In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating sodium channel slow inactivation. The Journal of Biological Chemistry. 285: 25296-307. PMID 20538611 DOI: 10.1074/Jbc.M110.128801 |
0.835 |
|
| 2010 |
Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. Sodium channels in normal and pathological pain. Annual Review of Neuroscience. 33: 325-47. PMID 20367448 DOI: 10.1146/Annurev-Neuro-060909-153234 |
0.65 |
|
| 2010 |
Jarecki BW, Piekarz AD, Jackson JO, Cummins TR. Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents. The Journal of Clinical Investigation. 120: 369-78. PMID 20038812 DOI: 10.1172/Jci40801 |
0.845 |
|
| 2009 |
Brittain JM, Piekarz AD, Wang Y, Kondo T, Cummins TR, Khanna R. An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. The Journal of Biological Chemistry. 284: 31375-90. PMID 19755421 DOI: 10.1074/Jbc.M109.009951 |
0.83 |
|
| 2009 |
Jarecki BW, Sheets PL, Xiao Y, Jackson JO, Cummins TR. Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T. Channels (Austin, Tex.). 3: 259-67. PMID 19633428 DOI: 10.4161/Chan.3.4.9341 |
0.856 |
|
| 2009 |
Dib-Hajj SD, Choi JS, Macala LJ, Tyrrell L, Black JA, Cummins TR, Waxman SG. Transfection of rat or mouse neurons by biolistics or electroporation. Nature Protocols. 4: 1118-26. PMID 19617884 DOI: 10.1038/Nprot.2009.90 |
0.66 |
|
| 2009 |
Cummins TR, Rush AM, Estacion M, Dib-Hajj SD, Waxman SG. Voltage-clamp and current-clamp recordings from mammalian DRG neurons. Nature Protocols. 4: 1103-12. PMID 19617882 DOI: 10.1038/Nprot.2009.91 |
0.713 |
|
| 2009 |
Dib-Hajj SD, Binshtok AM, Cummins TR, Jarvis MF, Samad T, Zimmermann K. Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment. Brain Research Reviews. 60: 65-83. PMID 19150627 DOI: 10.1016/J.Brainresrev.2008.12.005 |
0.669 |
|
| 2009 |
Jarecki BW, Piekarz AD, Jackson JO, Cummins TR. Impact Of NaV1.7-PEPD Missense Mutations That Slow The Rate Of Inactivation On Sensory Neuronal Resurgent Sodium Currents Biophysical Journal. 96: 663a. DOI: 10.1016/J.Bpj.2008.12.3506 |
0.855 |
|
| 2009 |
Cummins TR. Voltage-Gated Sodium Channels in Peripheral Nociceptive Neurons as Targets for the Treatment of Pain Peripheral Receptor Targets For Analgesia: Novel Approaches to Pain Management. 41-91. DOI: 10.1002/9780470522226.ch3 |
0.53 |
|
| 2009 |
Jarecki BW, Sheets PL, Xiao Y, Jackson JO, Cummins TR. Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T Channels. 3. |
0.829 |
|
| 2008 |
Dib-Hajj SD, Estacion M, Jarecki BW, Tyrrell L, Fischer TZ, Lawden M, Cummins TR, Waxman SG. Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable. Molecular Pain. 4: 37. PMID 18803825 DOI: 10.1186/1744-8069-4-37 |
0.871 |
|
| 2008 |
Xiao Y, Bingham JP, Zhu W, Moczydlowski E, Liang S, Cummins TR. Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration. The Journal of Biological Chemistry. 283: 27300-13. PMID 18628201 DOI: 10.1074/Jbc.M708447200 |
0.539 |
|
| 2008 |
Jarecki BW, Sheets PL, Jackson JO, Cummins TR. Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation. The Journal of Physiology. 586: 4137-53. PMID 18599537 DOI: 10.1113/Jphysiol.2008.154906 |
0.822 |
|
| 2008 |
Kondo T, Sheets PL, Zopf DA, Aloor HL, Cummins TR, Chan RJ, Hashino E. Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 5780-5. PMID 18391221 DOI: 10.1073/Pnas.0708704105 |
0.709 |
|
| 2008 |
Sheets PL, Heers C, Stoehr T, Cummins TR. Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine. The Journal of Pharmacology and Experimental Therapeutics. 326: 89-99. PMID 18378801 DOI: 10.1124/Jpet.107.133413 |
0.831 |
|
| 2007 |
Cummins TR, Rush AM. Voltage-gated sodium channel blockers for the treatment of neuropathic pain. Expert Review of Neurotherapeutics. 7: 1597-612. PMID 17997706 DOI: 10.1586/14737175.7.11.1597 |
0.532 |
|
| 2007 |
Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. From genes to pain: Na v 1.7 and human pain disorders. Trends in Neurosciences. 30: 555-63. PMID 17950472 DOI: 10.1016/J.Tins.2007.08.004 |
0.697 |
|
| 2007 |
Rush AM, Cummins TR. Painful research: identification of a small-molecule inhibitor that selectively targets Nav1.8 sodium channels. Molecular Interventions. 7: 192-5, 180. PMID 17827438 DOI: 10.1124/Mi.7.4.4 |
0.587 |
|
| 2007 |
Cummins TR, Sheets PL, Waxman SG. The roles of sodium channels in nociception: Implications for mechanisms of pain. Pain. 131: 243-57. PMID 17766042 DOI: 10.1016/J.Pain.2007.07.026 |
0.847 |
|
| 2007 |
Cummins TR. Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels. The Journal of Physiology. 582: 11. PMID 17525109 DOI: 10.1113/Jphysiol.2007.136671 |
0.568 |
|
| 2007 |
Sheets PL, Jackson JO, Waxman SG, Dib-Hajj SD, Cummins TR. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity. The Journal of Physiology. 581: 1019-31. PMID 17430993 DOI: 10.1113/Jphysiol.2006.127027 |
0.826 |
|
| 2007 |
Smith JJ, Cummins TR, Alphy S, Blumenthal KM. Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation. The Journal of Biological Chemistry. 282: 12687-97. PMID 17339321 DOI: 10.1074/Jbc.M610462200 |
0.514 |
|
| 2007 |
Rush AM, Cummins TR, Waxman SG. Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons. The Journal of Physiology. 579: 1-14. PMID 17158175 DOI: 10.1113/Jphysiol.2006.121483 |
0.681 |
|
| 2006 |
Sheets PL, Gerner P, Wang CF, Wang SY, Wang GK, Cummins TR. Inhibition of Nav1.7 and Nav1.4 sodium channels by trifluoperazine involves the local anesthetic receptor. Journal of Neurophysiology. 96: 1848-59. PMID 16807347 DOI: 10.1152/Jn.00354.2006 |
0.807 |
|
| 2006 |
Rush AM, Dib-Hajj SD, Liu S, Cummins TR, Black JA, Waxman SG. A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 8245-50. PMID 16702558 DOI: 10.1073/Pnas.0602813103 |
0.704 |
|
| 2006 |
Amir R, Argoff CE, Bennett GJ, Cummins TR, Durieux ME, Gerner P, Gold MS, Porreca F, Strichartz GR. The role of sodium channels in chronic inflammatory and neuropathic pain. The Journal of Pain : Official Journal of the American Pain Society. 7: S1-29. PMID 16632328 DOI: 10.1016/J.Jpain.2006.01.444 |
0.611 |
|
| 2006 |
Dib-Hajj SD, Rush AM, Cummins TR, Waxman SG. Mutations in the sodium channel Nav1.7 underlie inherited erythromelalgia Drug Discovery Today: Disease Mechanisms. 3: 343-350. DOI: 10.1016/J.Ddmec.2006.09.005 |
0.728 |
|
| 2005 |
Leffler A, Herzog RI, Dib-Hajj SD, Waxman SG, Cummins TR. Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue. PflüGers Archiv : European Journal of Physiology. 451: 454-63. PMID 15981012 DOI: 10.1007/S00424-005-1463-X |
0.584 |
|
| 2005 |
Dib-Hajj SD, Rush AM, Cummins TR, Hisama FM, Novella S, Tyrrell L, Marshall L, Waxman SG. Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons. Brain : a Journal of Neurology. 128: 1847-54. PMID 15958509 DOI: 10.1093/Brain/Awh514 |
0.694 |
|
| 2005 |
Cummins TR, Dib-Hajj SD, Herzog RI, Waxman SG. Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons. Febs Letters. 579: 2166-70. PMID 15811336 DOI: 10.1016/J.Febslet.2005.03.009 |
0.681 |
|
| 2005 |
Liu C, Cummins TR, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD. CAP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Na(v)1.8. Molecular and Cellular Neurosciences. 28: 636-49. PMID 15797711 DOI: 10.1016/J.Mcn.2004.11.007 |
0.634 |
|
| 2005 |
Cummins TR, Waxman SG. Neuronal Blocking Factors in Demyelinating Diseases Multiple Sclerosis as a Neuronal Disease. 317-326. DOI: 10.1016/B978-012738761-1/50023-7 |
0.434 |
|
| 2004 |
Cummins TR, Dib-Hajj SD, Waxman SG. Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8232-6. PMID 15385606 DOI: 10.1523/Jneurosci.2695-04.2004 |
0.735 |
|
| 2004 |
Black JA, Liu S, Tanaka M, Cummins TR, Waxman SG. Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain. 108: 237-47. PMID 15030943 DOI: 10.1016/J.Pain.2003.12.035 |
0.713 |
|
| 2003 |
Herzog RI, Liu C, Waxman SG, Cummins TR. Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8261-70. PMID 12967988 DOI: 10.1523/Jneurosci.23-23-08261.2003 |
0.628 |
|
| 2003 |
Saab CY, Cummins TR, Waxman SG. GTP gamma S increases Nav1.8 current in small-diameter dorsal root ganglia neurons. Experimental Brain Research. 152: 415-9. PMID 12898089 DOI: 10.1007/S00221-003-1565-7 |
0.626 |
|
| 2003 |
Herzog RI, Cummins TR, Ghassemi F, Dib-Hajj SD, Waxman SG. Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons. The Journal of Physiology. 551: 741-50. PMID 12843211 DOI: 10.1111/J.1469-7793.2003.00741.X |
0.71 |
|
| 2003 |
Brinkmeier H, Weber F, Aulkemeyer P, Wollinsky KH, Rüdel R, Cummins TR, Renganathan M, Herzog RI, Dib-Hajj SD, Waxman SG, Stys PK, Horn R. The pentapeptide QYNAD does not block voltage-gated sodium channels [4] (multiple letters) Neurology. 60: 1871-1872. PMID 12796562 |
0.685 |
|
| 2003 |
Black JA, Cummins TR, Yoshimura N, de Groat WC, Waxman SG. Tetrodotoxin-resistant sodium channels Na(v)1.8/SNS and Na(v)1.9/NaN in afferent neurons innervating urinary bladder in control and spinal cord injured rats. Brain Research. 963: 132-8. PMID 12560118 DOI: 10.1016/S0006-8993(02)03957-4 |
0.61 |
|
| 2003 |
Cummins TR, Renganathan M, Stys PK, Herzog RI, Scarfo K, Horn R, Dib-Hajj SD, Waxman SG. The pentapeptide QYNAD does not block voltage-gated sodium channels. Neurology. 60: 224-9. PMID 12552035 DOI: 10.1212/01.Wnl.0000042423.36650.Bd |
0.783 |
|
| 2003 |
Liu CJ, Dib-Hajj SD, Renganathan M, Cummins TR, Waxman SG. Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B. The Journal of Biological Chemistry. 278: 1029-36. PMID 12401812 DOI: 10.1074/Jbc.M207074200 |
0.656 |
|
| 2002 |
Cummins TR, Dib-Hajj SD, Waxman SG, Donnelly DF. Characterization and developmental changes of Na+ currents of petrosal neurons with projections to the carotid body. Journal of Neurophysiology. 88: 2993-3002. PMID 12466424 DOI: 10.1152/Jn.00350.2002 |
0.648 |
|
| 2002 |
Saab CY, Cummins TR, Dib-Hajj SD, Waxman SG. Molecular determinant of Na(v)1.8 sodium channel resistance to the venom from the scorpion Leiurus quinquestriatus hebraeus. Neuroscience Letters. 331: 79-82. PMID 12361845 DOI: 10.1016/S0304-3940(02)00860-1 |
0.633 |
|
| 2002 |
Klein JP, Craner MJ, Cummins TR, Black JA, Waxman SG. Sodium channel expression in hypothalamic osmosensitive neurons in experimental diabetes. Neuroreport. 13: 1481-4. PMID 12167778 DOI: 10.1097/00001756-200208070-00027 |
0.687 |
|
| 2002 |
Leffler A, Cummins TR, Dib-Hajj SD, Hormuzdiar WN, Black JA, Waxman SG. GDNF and NGF reverse changes in repriming of TTX-sensitive Na(+) currents following axotomy of dorsal root ganglion neurons. Journal of Neurophysiology. 88: 650-8. PMID 12163518 DOI: 10.1152/Jn.2002.88.2.650 |
0.653 |
|
| 2002 |
Dib-Hajj S, Black JA, Cummins TR, Waxman SG. NaN/Nav1.9: a sodium channel with unique properties. Trends in Neurosciences. 25: 253-9. PMID 11972962 DOI: 10.1016/S0166-2236(02)02150-1 |
0.684 |
|
| 2002 |
Bendahhou S, Cummins TR, Kula RW, Fu YH, Ptácek LJ. Impairment of slow inactivation as a common mechanism for periodic paralysis in DIIS4-S5. Neurology. 58: 1266-72. PMID 11971097 DOI: 10.1212/Wnl.58.8.1266 |
0.553 |
|
| 2002 |
Cummins TR, Aglieco F, Dib-Hajj SD. Critical molecular determinants of voltage-gated sodium channel sensitivity to mu-conotoxins GIIIA/B. Molecular Pharmacology. 61: 1192-201. PMID 11961138 DOI: 10.1124/Mol.61.5.1192 |
0.481 |
|
| 2002 |
White BH, Cummins TR, Wolf DH, Waxman SG, Russell DS, Kaczmarek LK. HSV-1 helper virus 5dl1.2 suppresses sodium currents in amplicon-transduced neurons. Journal of Neurophysiology. 87: 2149-57. PMID 11929932 DOI: 10.1152/Jn.00498.2001 |
0.542 |
|
| 2002 |
Renganathan M, Cummins TR, Waxman SG. Nitric oxide blocks fast, slow, and persistent Na+ channels in C-type DRG neurons by S-nitrosylation. Journal of Neurophysiology. 87: 761-75. PMID 11826045 DOI: 10.1152/Jn.00369.2001 |
0.672 |
|
| 2002 |
Waxman SG, Cummins TR, Black JA, Dib-Hajj S. Diverse functions and dynamic expression of neuronal sodium channels. Novartis Foundation Symposium. 241: 34-51; discussion 51. PMID 11771649 DOI: 10.1002/0470846682.Ch4 |
0.698 |
|
| 2001 |
Everill B, Cummins TR, Waxman SG, Kocsis JD. Sodium currents of large (Abeta-type) adult cutaneous afferent dorsal root ganglion neurons display rapid recovery from inactivation before and after axotomy. Neuroscience. 106: 161-9. PMID 11564426 DOI: 10.1016/S0306-4522(01)00258-5 |
0.615 |
|
| 2001 |
Bendahhou S, Cummins TR, Griggs RC, Fu YH, Ptácek LJ. Sodium channel inactivation defects are associated with acetazolamide-exacerbated hypokalemic periodic paralysis. Annals of Neurology. 50: 417-20. PMID 11558801 DOI: 10.1002/Ana.1144 |
0.577 |
|
| 2001 |
Herzog RI, Cummins TR, Waxman SG. Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. Journal of Neurophysiology. 86: 1351-64. PMID 11535682 DOI: 10.1152/Jn.2001.86.3.1351 |
0.613 |
|
| 2001 |
Renganathan M, Cummins TR, Waxman SG. Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. Journal of Neurophysiology. 86: 629-40. PMID 11495938 DOI: 10.1152/Jn.2001.86.2.629 |
0.664 |
|
| 2001 |
Cummins TR, Aglieco F, Renganathan M, Herzog RI, Dib-Hajj SD, Waxman SG. Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5952-61. PMID 11487618 DOI: 10.1523/Jneurosci.21-16-05952.2001 |
0.716 |
|
| 2001 |
Kearney JA, Plummer NW, Smith MR, Kapur J, Cummins TR, Waxman SG, Goldin AL, Meisler MH. A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience. 102: 307-17. PMID 11166117 DOI: 10.1016/S0306-4522(00)00479-6 |
0.574 |
|
| 2000 |
Waxman SG, Cummins TR, Dib-Hajj SD, Black JA. Voltage-gated sodium channels and the molecular pathogenesis of pain: a review. Journal of Rehabilitation Research and Development. 37: 517-28. PMID 11322150 |
0.683 |
|
| 2000 |
Waxman SG, Dib-Hajj S, Cummins TR, Black JA. Sodium channels and their genes: dynamic expression in the normal nervous system, dysregulation in disease states(1). Brain Research. 886: 5-14. PMID 11119683 DOI: 10.1016/S0006-8993(00)02774-8 |
0.674 |
|
| 2000 |
Cummins TR, Black JA, Dib-Hajj SD, Waxman SG. Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8754-61. PMID 11102483 DOI: 10.1523/Jneurosci.20-23-08754.2000 |
0.685 |
|
| 2000 |
Cummins TR, Dib-Hajj SD, Black JA, Waxman SG. Sodium channels and the molecular pathophysiology of pain. Progress in Brain Research. 129: 3-19. PMID 11098678 DOI: 10.1016/S0079-6123(00)29002-X |
0.684 |
|
| 2000 |
Sleeper AA, Cummins TR, Dib-Hajj SD, Hormuzdiar W, Tyrrell L, Waxman SG, Black JA. Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7279-89. PMID 11007885 DOI: 10.1523/Jneurosci.20-19-07279.2000 |
0.625 |
|
| 2000 |
Renganathan M, Cummins TR, Hormuzdiar WN, Waxman SG. alpha-SNS produces the slow TTX-resistant sodium current in large cutaneous afferent DRG neurons. Journal of Neurophysiology. 84: 710-8. PMID 10938298 DOI: 10.1152/Jn.2000.84.2.710 |
0.657 |
|
| 2000 |
Bendahhou S, Cummins TR, Hahn AF, Langlois S, Waxman SG, Ptácek LJ. A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation. The Journal of Clinical Investigation. 106: 431-8. PMID 10930446 DOI: 10.1172/Jci9654 |
0.648 |
|
| 2000 |
Renganathan M, Cummins TR, Hormuzdiar WN, Black JA, Waxman SG. Nitric oxide is an autocrine regulator of Na(+) currents in axotomized C-type DRG neurons. Journal of Neurophysiology. 83: 2431-42. PMID 10758144 DOI: 10.1152/Jn.2000.83.4.2431 |
0.63 |
|
| 1999 |
Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN, Waxman SG. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC43. PMID 10594087 DOI: 10.1523/Jneurosci.19-24-J0001.1999 |
0.656 |
|
| 1999 |
Dib-Hajj SD, Tyrrell L, Cummins TR, Black JA, Wood PM, Waxman SG. Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons. Febs Letters. 462: 117-20. PMID 10580103 DOI: 10.1016/S0014-5793(99)01519-7 |
0.682 |
|
| 1999 |
Dib-Hajj SD, Fjell J, Cummins TR, Zheng Z, Fried K, LaMotte R, Black JA, Waxman SG. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain. 83: 591-600. PMID 10568868 DOI: 10.1016/S0304-3959(99)00169-4 |
0.705 |
|
| 1999 |
Black JA, Cummins TR, Plumpton C, Chen YH, Hormuzdiar W, Clare JJ, Waxman SG. Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. Journal of Neurophysiology. 82: 2776-85. PMID 10561444 DOI: 10.1152/Jn.1999.82.5.2776 |
0.662 |
|
| 1999 |
Waxman SG, Cummins TR, Dib-Hajj S, Fjell J, Black JA. Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain. Muscle & Nerve. 22: 1177-87. PMID 10454712 DOI: 10.1002/(Sici)1097-4598(199909)22:9<1177::Aid-Mus3>3.0.Co;2-P |
0.718 |
|
| 1999 |
Fjell J, Cummins TR, Davis BM, Albers KM, Fried K, Waxman SG, Black JA. Sodium channel expression in NGF-overexpressing transgenic mice. Journal of Neuroscience Research. 57: 39-47. PMID 10397634 DOI: 10.1002/(Sici)1097-4547(19990701)57:1<39::Aid-Jnr5>3.0.Co;2-M |
0.595 |
|
| 1999 |
Waxman SG, Dib-Hajj S, Cummins TR, Black JA. Sodium channels and pain. Proceedings of the National Academy of Sciences of the United States of America. 96: 7635-9. PMID 10393872 DOI: 10.1073/Pnas.96.14.7635 |
0.704 |
|
| 1999 |
Bendahhou S, Cummins TR, Kwiecinski H, Waxman SG, Ptácek LJ. Characterization of a new sodium channel mutation at arginine 1448 associated with moderate Paramyotonia congenita in humans. The Journal of Physiology. 518: 337-44. PMID 10381583 DOI: 10.1111/J.1469-7793.1999.0337P.X |
0.664 |
|
| 1999 |
Bendahhou S, Cummins TR, Tawil R, Waxman SG, Ptácek LJ. Activation and inactivation of the voltage-gated sodium channel: role of segment S5 revealed by a novel hyperkalaemic periodic paralysis mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4762-71. PMID 10366610 |
0.448 |
|
| 1999 |
Fjell J, Cummins TR, Dib-Hajj SD, Fried K, Black JA, Waxman SG. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. Brain Research. Molecular Brain Research. 67: 267-82. PMID 10216225 DOI: 10.1016/S0169-328X(99)00070-4 |
0.628 |
|
| 1999 |
Fjell J, Cummins TR, Fried K, Black JA, Waxman SG. In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons. Journal of Neurophysiology. 81: 803-10. PMID 10036280 DOI: 10.1152/Jn.1999.81.2.803 |
0.603 |
|
| 1999 |
Tanaka M, Cummins TR, Ishikawa K, Black JA, Ibata Y, Waxman SG. Molecular and functional remodeling of electrogenic membrane of hypothalamic neurons in response to changes in their input. Proceedings of the National Academy of Sciences of the United States of America. 96: 1088-93. PMID 9927698 DOI: 10.1073/Pnas.96.3.1088 |
0.667 |
|
| 1999 |
Bendahhou S, Cummins TR, Tawil R, Waxman SG, Ptácek LJ. Activation and Inactivation of the Voltage-Gated Sodium Channel: Role of Segment S5 Revealed by a Novel Hyperkalaemic Periodic Paralysis Mutation The Journal of Neuroscience. 19: 4762-4771. DOI: 10.1523/Jneurosci.19-12-04762.1999 |
0.639 |
|
| 1998 |
Cummins TR, Howe JR, Waxman SG. Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9607-19. PMID 9822722 |
0.566 |
|
| 1998 |
Tanaka M, Cummins TR, Ishikawa K, Dib-Hajj SD, Black JA, Waxman SG. SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport. 9: 967-72. PMID 9601651 DOI: 10.1097/00001756-199804200-00003 |
0.661 |
|
| 1998 |
Dib-Hajj SD, Black JA, Cummins TR, Kenney AM, Kocsis JD, Waxman SG. Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. Journal of Neurophysiology. 79: 2668-76. PMID 9582237 DOI: 10.1152/Jn.1998.79.5.2668 |
0.585 |
|
| 1998 |
Cummins TR, Howe JR, Waxman SG. Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel The Journal of Neuroscience. 18: 9607-9619. DOI: 10.1523/Jneurosci.18-23-09607.1998 |
0.714 |
|
| 1997 |
O'Reilly JP, Cummins TR, Haddad GG. Oxygen deprivation inhibits Na+ current in rat hippocampal neurones via protein kinase C. The Journal of Physiology. 503: 479-88. PMID 9379405 DOI: 10.1111/J.1469-7793.1997.479Bg.X |
0.355 |
|
| 1997 |
Dib-Hajj SD, Ishikawa K, Cummins TR, Waxman SG. Insertion of a SNS-specific tetrapeptide in S3-S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage-gated Na channel mu1 in HEK293 cells. Febs Letters. 416: 11-4. PMID 9369222 DOI: 10.1016/S0014-5793(97)01154-X |
0.653 |
|
| 1997 |
Cummins TR, Waxman SG. Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3503-14. PMID 9133375 |
0.481 |
|
| 1997 |
Bendahhou S, Cummins TR, Agnew WS. Mechanism of modulation of the voltage-gated skeletal and cardiac muscle sodium channels by fatty acids. The American Journal of Physiology. 272: C592-600. PMID 9124303 |
0.433 |
|
| 1997 |
Cummins TR, Waxman SG. Downregulation of Tetrodotoxin-Resistant Sodium Currents and Upregulation of a Rapidly Repriming Tetrodotoxin-Sensitive Sodium Current in Small Spinal Sensory Neurons after Nerve Injury The Journal of Neuroscience. 17: 3503-3514. DOI: 10.1523/Jneurosci.17-10-03503.1997 |
0.659 |
|
| 1996 |
Bevensee MO, Cummins TR, Haddad GG, Boron WF, Boyarsky G. pH regulation in single CA1 neurons acutely isolated from the hippocampi of immature and mature rats. The Journal of Physiology. 494: 315-28. PMID 8841993 DOI: 10.1113/Jphysiol.1996.Sp021494 |
0.379 |
|
| 1996 |
Cummins TR, Sigworth FJ. Impaired slow inactivation in mutant sodium channels. Biophysical Journal. 71: 227-36. PMID 8804606 DOI: 10.1016/S0006-3495(96)79219-6 |
0.723 |
|
| 1995 |
Bendahhou S, Cummins TR, Potts JF, Tong J, Agnew WS. Serine-1321-independent regulation of the mu 1 adult skeletal muscle Na+ channel by protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 92: 12003-7. PMID 8618832 DOI: 10.1073/Pnas.92.26.12003 |
0.504 |
|
| 1994 |
Cummins TR, Xia Y, Haddad GG. Functional properties of rat and human neocortical voltage-sensitive sodium currents. Journal of Neurophysiology. 71: 1052-64. PMID 8201401 DOI: 10.1152/Jn.1994.71.3.1052 |
0.506 |
|
| 1994 |
Jiang C, Cummins TR, Haddad GG. Membrane ionic currents and properties of freshly dissociated rat brainstem neurons. Experimental Brain Research. 100: 407-20. PMID 7813679 DOI: 10.1007/Bf00229181 |
0.535 |
|
| 1993 |
Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS. Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis. Neuron. 10: 667-78. PMID 8386527 DOI: 10.1016/0896-6273(93)90168-Q |
0.715 |
|
| 1993 |
Cummins TR, Jiang C, Haddad GG. Human neocortical excitability is decreased during anoxia via sodium channel modulation. The Journal of Clinical Investigation. 91: 608-15. PMID 8381823 DOI: 10.1172/Jci116241 |
0.507 |
|
| 1991 |
Cummins TR, Donnelly DF, Haddad GG. Effect of metabolic inhibition on the excitability of isolated hippocampal CA1 neurons: developmental aspects. Journal of Neurophysiology. 66: 1471-82. PMID 1662712 DOI: 10.1152/Jn.1991.66.5.1471 |
0.531 |
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