Year |
Citation |
Score |
2023 |
Boeke JD, Burns KH, Chiappinelli KB, Classon M, Coffin JM, DeCarvalho DD, Dukes JD, Greenbaum B, Kassiotis G, Knutson SK, Levine AJ, Nath A, Papa S, Rios D, Sedivy J, et al. Proceedings of the inaugural Dark Genome Symposium: November 2022. Mobile Dna. 14: 18. PMID 37990347 DOI: 10.1186/s13100-023-00306-5 |
0.524 |
|
2022 |
Hoyos D, Zappasodi R, Schulze I, Sethna Z, de Andrade KC, Bajorin DF, Bandlamudi C, Callahan MK, Funt SA, Hadrup SR, Holm JS, Rosenberg JE, Shah SP, Vázquez-García I, Weigelt B, ... ... Levine AJ, et al. Author Correction: Fundamental immune-oncogenicity trade-offs define driver mutation fitness. Nature. PMID 35641605 DOI: 10.1038/s41586-022-04879-8 |
0.529 |
|
2022 |
Hoyos D, Zappasodi R, Schulze I, Sethna Z, de Andrade KC, Bajorin DF, Bandlamundi C, Callahan MK, Funt SA, Hadrup SR, Holm JS, Rosenberg JE, Shah SP, Vázquez-García I, Weigelt B, ... ... Levine AJ, et al. Fundamental immune-oncogenicity trade-offs define driver mutation fitness. Nature. PMID 35545680 DOI: 10.1038/s41586-022-04696-z |
0.572 |
|
2022 |
Hoyos D, Greenbaum B, Levine AJ. The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein. Cell Death and Differentiation. 29: 938-945. PMID 35383292 DOI: 10.1038/s41418-022-00980-7 |
0.573 |
|
2019 |
Nogalski MT, Solovyov A, Kulkarni AS, Desai N, Oberstein A, Levine AJ, Ting DT, Shenk T, Greenbaum BD. A tumor-specific endogenous repetitive element is induced by herpesviruses. Nature Communications. 10: 90. PMID 30626867 DOI: 10.1038/S41467-018-07944-X |
0.606 |
|
2017 |
Balachandran VP, Łuksza M, Zhao JN, Makarov V, Moral JA, Remark R, Herbst B, Askan G, Bhanot U, Senbabaoglu Y, Wells DK, Cary CIO, Grbovic-Huezo O, Attiyeh M, Medina B, ... ... Levine AJ, et al. Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. Nature. PMID 29132146 DOI: 10.1038/Nature24462 |
0.542 |
|
2017 |
Łuksza M, Riaz N, Makarov V, Balachandran VP, Hellmann MD, Solovyov A, Rizvi NA, Merghoub T, Levine AJ, Chan TA, Wolchok JD, Greenbaum BD. A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy. Nature. PMID 29132144 DOI: 10.1038/Nature24473 |
0.561 |
|
2016 |
Zhu J, Dou Z, Sammons MA, Levine AJ, Berger SL. Lysine methylation represses p53 activity in teratocarcinoma cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27535933 DOI: 10.1073/Pnas.1610387113 |
0.305 |
|
2016 |
Levine AJ, Ting DT, Greenbaum BD. P53 and the defenses against genome instability caused by transposons and repetitive elements. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 27172878 DOI: 10.1002/Bies.201600031 |
0.623 |
|
2016 |
Tanne A, Muniz L, Ting D, Levine A, Bhardwaj N, Greenbaum B. Abstract A077: Unraveling predicted immunomodulatory effects of novel cancer-associated noncoding RNAs Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A077 |
0.643 |
|
2016 |
Solovyov A, Tanne A, Muniz L, Cocco S, Monasson R, Levine A, Ting DT, Bhardwaj N, Greenbaum B. Abstract A087: Quantifying the landscape of immunostimulatory tumoral RNA Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A087 |
0.622 |
|
2016 |
Solovyov A, Tanne A, Ting D, Levine A, Bhardwaj N, Greenbaum B. Abstract 531: The landscape of immunostimulatory RNA transcription Cancer Research. 76: 531-531. DOI: 10.1158/1538-7445.Am2016-531 |
0.636 |
|
2016 |
Wong C, Vosburgh E, Levine A, Proia D, Xu E. Abstract 267: Preclinical investigation of the HSP90 inhibitor, ganetespib, in combination with FDA-approved cytotoxic agents for their potential anti-tumor effects on human neuroendocrine tumors Cancer Research. 76: 267-267. DOI: 10.1158/1538-7445.Am2016-267 |
0.327 |
|
2015 |
Tanne A, Muniz LR, Puzio-Kuter A, Leonova KI, Gudkov AV, Ting DT, Monasson R, Cocco S, Levine AJ, Bhardwaj N, Greenbaum BD. Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26575629 DOI: 10.1073/Pnas.1517584112 |
0.608 |
|
2015 |
Levine AJ, Phipps AI, Baron JA, Buchanan DD, Ahnen DJ, Cohen S, Lindor NM, Newcomb PA, Rosty C, Haile RW, Laird PW, Weisenberger DJ. Clinicopathological risk factor distributions for MLH1 promoter region methylation in CIMP positive tumors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26512054 DOI: 10.1158/1055-9965.Epi-15-0935 |
0.492 |
|
2015 |
Weisenberger DJ, Levine AJ, Long TI, Buchanan DD, Walters R, Clendenning M, Rosty C, Joshi AD, Stern MC, Le Marchand L, Lindor NM, Daftary D, Gallinger S, Selander T, Bapat B, et al. Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 512-9. PMID 25587051 DOI: 10.1158/1055-9965.Epi-14-1161 |
0.471 |
|
2015 |
Tanne AJ, Muniz LR, Ting DT, Solovyov AV, Levine A, Greenbaum B, Bhardwaj N. Unraveling predicted immunomodulatory effects of novel cancer-associated non-coding RNAs Journal For Immunotherapy of Cancer. 3: P396. DOI: 10.1186/2051-1426-3-S2-P396 |
0.639 |
|
2014 |
Yi L, Sun Y, Levine A. Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells. Oncotarget. 5: 8924-36. PMID 25238040 DOI: 10.18632/Oncotarget.2441 |
0.405 |
|
2014 |
Greenbaum BD, Cocco S, Levine AJ, Monasson R. Quantitative theory of entropic forces acting on constrained nucleotide sequences applied to viruses. Proceedings of the National Academy of Sciences of the United States of America. 111: 5054-9. PMID 24639520 DOI: 10.1073/Pnas.1402285111 |
0.539 |
|
2013 |
Zhang C, Lin M, Zhao Y, Zheng T, Wang J, Levine A, Feng Z, Hu W. Abstract 784: Chronic stress promotes tumorigenesis through attenuation of p53 function . Cancer Research. 73: 784-784. DOI: 10.1158/1538-7445.Am2013-784 |
0.346 |
|
2012 |
Levine AJ, Greenbaum B. The maintenance of epigenetic states by p53: the guardian of the epigenome. Oncotarget. 3: 1503-4. PMID 23237909 DOI: 10.18632/Oncotarget.780 |
0.588 |
|
2012 |
Cortessis VK, Thomas DC, Levine AJ, Breton CV, Mack TM, Siegmund KD, Haile RW, Laird PW. Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships. Human Genetics. 131: 1565-89. PMID 22740325 DOI: 10.1007/S00439-012-1189-8 |
0.435 |
|
2012 |
Greenbaum BD, Li OT, Poon LL, Levine AJ, Rabadan R. Viral reassortment as an information exchange between viral segments. Proceedings of the National Academy of Sciences of the United States of America. 109: 3341-6. PMID 22331898 DOI: 10.1073/Pnas.1113300109 |
0.525 |
|
2012 |
Levine AJ, Win AK, Buchanan DD, Jenkins MA, Baron JA, Young JP, Long TI, Weisenberger DJ, Laird PW, McCall RL, Duggan DJ, Haile RW. Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry. Cancer Prevention Research (Philadelphia, Pa.). 5: 328-35. PMID 22144422 DOI: 10.1158/1940-6207.Capr-11-0419 |
0.453 |
|
2011 |
Blandino G, Deppert W, Hainaut P, Levine A, Lozano G, Olivier M, Rotter V, Wiman K, Oren M. Mutant p53 protein, master regulator of human malignancies: a report on the Fifth Mutant p53 Workshop. Cell Death and Differentiation. 19: 180-3. PMID 22095277 DOI: 10.1038/Cdd.2011.148 |
0.334 |
|
2011 |
Jimenez-Baranda S, Greenbaum B, Manches O, Handler J, Rabadán R, Levine A, Bhardwaj N. Oligonucleotide motifs that disappear during the evolution of influenza virus in humans increase alpha interferon secretion by plasmacytoid dendritic cells. Journal of Virology. 85: 3893-904. PMID 21307198 DOI: 10.1128/Jvi.01908-10 |
0.608 |
|
2010 |
Lane D, Levine A. p53 Research: the past thirty years and the next thirty years. Cold Spring Harbor Perspectives in Biology. 2: a000893. PMID 20463001 DOI: 10.1101/Cshperspect.A000893 |
0.382 |
|
2010 |
Hu W, Zhang C, Wu R, Sun Y, Levine A, Feng Z. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proceedings of the National Academy of Sciences of the United States of America. 107: 7455-60. PMID 20378837 DOI: 10.1073/Pnas.1001006107 |
0.347 |
|
2009 |
Greenbaum BD, Rabadan R, Levine AJ. Patterns of oligonucleotide sequences in viral and host cell RNA identify mediators of the host innate immune system. Plos One. 4: e5969. PMID 19536338 DOI: 10.1371/Journal.Pone.0005969 |
0.565 |
|
2009 |
Shi H, Tan SJ, Zhong H, Hu W, Levine A, Xiao CJ, Peng Y, Qi XB, Shou WH, Ma RL, Li Y, Su B, Lu X. Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia. American Journal of Human Genetics. 84: 534-41. PMID 19344876 DOI: 10.1016/J.Ajhg.2009.03.009 |
0.316 |
|
2008 |
Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor N, Young J, Jenkins MA, Hopper JL, Baron JA, Buchanan D, Casey G, Levine AJ, Le Marchand L, Gallinger S, et al. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3208-15. PMID 18990764 DOI: 10.1158/1055-9965.Epi-08-0512 |
0.453 |
|
2008 |
Greenbaum BD, Levine AJ, Bhanot G, Rabadan R. Patterns of evolution and host gene mimicry in influenza and other RNA viruses. Plos Pathogens. 4: e1000079. PMID 18535658 DOI: 10.1371/Journal.Ppat.1000079 |
0.577 |
|
2008 |
Yeang CH, McCormick F, Levine A. Combinatorial patterns of somatic gene mutations in cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2605-22. PMID 18434431 DOI: 10.1096/Fj.08-108985 |
0.332 |
|
2008 |
Riley T, Sontag E, Chen P, Levine A. Transcriptional control of human p53-regulated genes. Nature Reviews. Molecular Cell Biology. 9: 402-12. PMID 18431400 DOI: 10.1038/Nrm2395 |
0.399 |
|
2007 |
Hu W, Feng Z, Teresky A, Levine A. Identifying novel p53-target genes and their functional analysis Nature Protocols. DOI: 10.1038/Nprot.2007.507 |
0.305 |
|
2006 |
Siegmund KD, Levine AJ, Chang J, Laird PW. Modeling exposures for DNA methylation profiles. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 567-72. PMID 16537717 DOI: 10.1158/1055-9965.Epi-05-0717 |
0.428 |
|
2005 |
Bond GL, Hu W, Levine A. A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect. Cancer Research. 65: 5481-4. PMID 15994915 DOI: 10.1158/0008-5472.Can-05-0825 |
0.324 |
|
2004 |
Chen W, Cooper TK, Zahnow CA, Overholtzer M, Zhao Z, Ladanyi M, Karp JE, Gokgoz N, Wunder JS, Andrulis IL, Levine AJ, Mankowski JL, Baylin SB. Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis. Cancer Cell. 6: 387-98. PMID 15488761 DOI: 10.1016/J.Ccr.2004.08.030 |
0.616 |
|
2003 |
Overholtzer M, Rao PH, Favis R, Lu XY, Elowitz MB, Barany F, Ladanyi M, Gorlick R, Levine AJ. The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 100: 11547-52. PMID 12972634 DOI: 10.1073/Pnas.1934852100 |
0.636 |
|
2003 |
Jin S, Kalkum M, Overholtzer M, Stoffel A, Chait BT, Levine AJ. CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. Genes & Development. 17: 359-67. PMID 12569127 DOI: 10.1101/Gad.1047003 |
0.594 |
|
2003 |
Soon LL, Yie TA, Shvarts A, Levine AJ, Su F, Tchou-Wong KM. Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation. The Journal of Biological Chemistry. 278: 11465-70. PMID 12529380 DOI: 10.1074/jbc.M210945200 |
0.438 |
|
2002 |
Su F, Overholtzer M, Besser D, Levine AJ. WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. Genes & Development. 16: 46-57. PMID 11782444 DOI: 10.1101/Gad.942902 |
0.678 |
|
2001 |
Tao W, Pennica D, Xu L, Kalejta RF, Levine AJ. Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1. Genes & Development. 15: 1796-807. PMID 11459829 DOI: 10.1101/Gad.894301 |
0.506 |
|
2000 |
Jin S, Martinek S, Joo WS, Wortman JR, Mirkovic N, Sali A, Yandell MD, Pavletich NP, Young MW, Levine AJ. Identification and characterization of a p53 homologue in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 97: 7301-6. PMID 10860994 DOI: 10.1073/Pnas.97.13.7301 |
0.313 |
|
2000 |
Xu L, Corcoran RB, Welsh JW, Pennica D, Levine AJ. WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene. Genes & Development. 14: 585-95. PMID 10716946 |
0.482 |
|
1999 |
Ahn J, Murphy M, Kratowicz S, Wang A, Levine AJ, George DL. Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction. Oncogene. 18: 5954-8. PMID 10557083 DOI: 10.1038/sj.onc.1202986 |
0.301 |
|
1998 |
Pennica D, Swanson TA, Welsh JW, Roy MA, Lawrence DA, Lee J, Brush J, Taneyhill LA, Deuel B, Lew M, Watanabe C, Cohen RL, Melhem MF, Finley GG, Quirke P, ... ... Levine AJ, et al. WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proceedings of the National Academy of Sciences of the United States of America. 95: 14717-22. PMID 9843955 DOI: 10.1073/Pnas.95.25.14717 |
0.671 |
|
1998 |
Zhang CC, Yang JM, White E, Murphy M, Levine A, Hait WN. The role of MAP4 expression in the sensitivity to paclitaxel and resistance to vinca alkaloids in p53 mutant cells. Oncogene. 16: 1617-24. PMID 9569030 DOI: 10.1038/Sj.Onc.1201658 |
0.31 |
|
1997 |
Marechal V, Elenbaas B, Taneyhill L, Piette J, Mechali M, Nicolas J, Levine AJ, Moreau J. Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis. Oncogene. 14: 1427-1433. PMID 9136986 DOI: 10.1038/Sj.Onc.1200967 |
0.671 |
|
1996 |
Lutzker SG, Levine AJ. A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation. Nature Medicine. 2: 804-10. PMID 8673928 DOI: 10.1038/nm0796-804 |
0.33 |
|
1995 |
Riou G, Barrois M, Prost S, Terrier MJ, Theodore C, Levine AJ. The p53 and mdm-2 genes in human testicular germ-cell tumors. Molecular Carcinogenesis. 12: 124-31. PMID 7893365 DOI: 10.1002/mc.2940120303 |
0.305 |
|
1995 |
Lee S, Elenbaas B, Levine A, Griffith J. p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches Cell. 81: 1013-1020. PMID 7600570 DOI: 10.1016/S0092-8674(05)80006-6 |
0.333 |
|
1994 |
Wu X, Levine AJ. p53 and E2F-1 cooperate to mediate apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 91: 3602-6. PMID 8170954 DOI: 10.1073/pnas.91.9.3602 |
0.304 |
|
1994 |
Levine AJ, Perry ME, Chang A, Silver A, Dittmer D, Wu M, Welsh D. The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis. British Journal of Cancer. 69: 409-16. PMID 8123467 DOI: 10.1038/bjc.1994.76 |
0.308 |
|
1992 |
Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation Cell. 69: 1237-1245. PMID 1535557 DOI: 10.1016/0092-8674(92)90644-R |
0.686 |
|
1992 |
Seto E, Usheva A, Zambetti GP, Momand J, Horikoshi N, Weinmann R, Levine AJ, Shenk T. Wild-type p53 binds to the TATA-binding protein and represses transcription Proceedings of the National Academy of Sciences of the United States of America. 89: 12028-12032. PMID 1465435 DOI: 10.1073/Pnas.89.24.12028 |
0.674 |
|
1991 |
Levine AJ, Momand J, Finlay CA. The p53 tumour suppressor gene. Nature. 351: 453-6. PMID 2046748 DOI: 10.1038/351453A0 |
0.702 |
|
1991 |
Zambetti GP, Quartin RS, Martinez J, Georgoff I, Momand J, Dittmer D, Finlay CA, Levine AJ. Regulation of transformation and the cell cycle by p53 Cold Spring Harbor Symposia On Quantitative Biology. 56: 219-225. PMID 1819488 DOI: 10.1101/Sqb.1991.056.01.027 |
0.659 |
|
1990 |
Levine AJ, Momand J. Tumor suppressor genes: the p53 and retinoblastoma sensitivity genes and gene products. Biochimica Et Biophysica Acta. 1032: 119-36. PMID 2142001 DOI: 10.1016/0304-419X(90)90015-S |
0.659 |
|
1990 |
Levine AJ. Tumor suppressor genes Bioessays. 12: 60-66. PMID 2140509 DOI: 10.1002/bies.950120203 |
0.326 |
|
1975 |
Van Der Vliet PC, Levine AJ, Ensinger MJ, Ginsberg HS. Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis. Journal of Virology. 15: 348-54. PMID 803568 DOI: 10.1128/jvi.15.2.348-354.1975 |
0.51 |
|
1975 |
Sen A, Laipis PJ, Levine AJ. DNA replication in SV40-infected cells. XI. The properties of SV40 DNA and nucleoprotein complex synthesized in the presence of cycloheximide. Intervirology. 5: 122-36. PMID 172469 DOI: 10.1159/000149890 |
0.593 |
|
1975 |
Laipis PJ, Sen A, Levine AJ, Mulder C. DNA replication in SV40 infected cells X. The structure of the 16 S gap circle intermediate in SV40 DNA synthesis. Virology. 68: 115-23. PMID 171842 DOI: 10.1016/0042-6822(75)90153-1 |
0.591 |
|
1973 |
Laipis PJ, Levine AJ. DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step during discontinuous synthesis of SV40 DNA. Virology. 56: 580-94. PMID 4357056 DOI: 10.1016/0042-6822(73)90059-7 |
0.598 |
|
1973 |
Jaenisch R, Levine AJ. DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and circular dimers. Journal of Molecular Biology. 73: 199-212. PMID 4347738 |
0.428 |
|
1972 |
Jaenisch R, Levine AJ. DNA replication in SV40-infected cells. VI. The effect of cycloheximide on the formation of SV40 oligomeric DNA. Virology. 48: 373-9. PMID 4337027 |
0.423 |
|
1972 |
Dubbs DR, Kit S, Jaenisch R, Levine AJ. Isolation of simian virus 40 recombinants from cells infected with oligomeric forms of simian virus 40 deoxyribonucleic acid. Journal of Virology. 9: 717-9. PMID 4336567 DOI: 10.1128/Jvi.9.4.717-719.1972 |
0.419 |
|
1971 |
Jaenisch R, Levine AJ. Infection of primary African green monkey cells with SV40 monomeric and dimeric DNA. Journal of Molecular Biology. 61: 735-8. PMID 4332233 |
0.413 |
|
1971 |
Jaenisch R, Mayer A, Levine A. Replicating SV40 molecules containing closed circular template DNA strands. Nature. 233: 72-75. PMID 4330296 DOI: 10.1038/Newbio233072A0 |
0.301 |
|
1969 |
Levine AJ, Sinsheimer RL. The process of infection with bacteriophage phiX174. XXVII. Synthesis of a viral-specific chloramphenicol-resistant protein in phiX174-infected cells. Journal of Molecular Biology. 39: 655-68. PMID 5357216 DOI: 10.1016/0022-2836(69)90151-X |
0.495 |
|
1969 |
Levine AJ, Sinsheimer RL. Isolation of a chloramphenicol-resistant protein from lambda-infected cells. Proceedings of the National Academy of Sciences of the United States of America. 62: 1226-8. PMID 5256419 DOI: 10.1073/Pnas.62.4.1226 |
0.501 |
|
1969 |
Levine AJ, Sinsheimer RL. The process of infection with bacteriophage phiX174. XXV. Studies with bacteriophage phiX174 mutants blocked in progeny replicative form DNA synthesis. Journal of Molecular Biology. 39: 619-39. PMID 4901860 DOI: 10.1016/0022-2836(69)90149-1 |
0.494 |
|
1968 |
Levine AJ, Sinsheimer RL. The process of infection with bacteriophage phi-X174. XIX. Isolation and characterization of a chloramphenicol-resistant protein from phi-X-infected cells. Journal of Molecular Biology. 32: 567-78. PMID 4868758 DOI: 10.1016/0022-2836(68)90343-4 |
0.483 |
|
1968 |
Levine AJ, Ginsberg HS. Role of adenovirus structural proteins in the cessation of host-cell biosynthetic functions. Journal of Virology. 2: 430-9. PMID 4301313 |
0.52 |
|
1967 |
Levine AJ, Ginsberg HS. Mechanism by which fiber antigen inhibits multiplication of type 5 adenovirus. Journal of Virology. 1: 747-57. PMID 5630225 |
0.487 |
|
Low-probability matches (unlikely to be authored by this person) |
1998 |
Ahmed Y, Hayashi S, Levine A, Wieschaus E. Regulation of Armadillo by a Drosophila APC inhibits neuronal apoptotis during retinal development Cell. 93: 1171-1182. PMID 9657150 DOI: 10.1016/S0092-8674(00)81461-0 |
0.299 |
|
1995 |
Xiao ZX, Chen J, Levine AJ, Modjtahedi N, Xing J, Sellers WR, Livingston DM. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature. 375: 694-8. PMID 7791904 DOI: 10.1038/375694A0 |
0.292 |
|
1989 |
Levine AJ. The p53 tumor suppressor gene and gene product Princess Takamatsu Symposia. 20: 221-230. PMID 2488233 |
0.291 |
|
1991 |
Kern SE, Kinzler KW, Baker SJ, Nigro JM, Rotter V, Levine AJ, Friedman P, Prives C, Vogelstein B. Mutant p53 proteins bind DNA abnormally in vitro. Oncogene. 6: 131-6. PMID 1846954 |
0.29 |
|
1996 |
Roth J, Dittmer D, Rea D, Tartaglia J, Paoletti E, Levine AJ. p53 as a target for cancer vaccines: recombinant canarypox virus vectors expressing p53 protect mice against lethal tumor cell challenge. Proceedings of the National Academy of Sciences of the United States of America. 93: 4781-6. PMID 8643480 DOI: 10.1073/pnas.93.10.4781 |
0.29 |
|
2013 |
Giacobbe A, Bongiorno-Borbone L, Bernassola F, Terrinoni A, Markert EK, Levine AJ, Feng Z, Agostini M, Zolla L, Agrò AF, Notterman DA, Melino G, Peschiaroli A. p63 regulates glutaminase 2 expression. Cell Cycle (Georgetown, Tex.). 12: 1395-405. PMID 23574722 DOI: 10.4161/cc.24478 |
0.289 |
|
2012 |
Dolfi SC, Kulkarni D, Lu S, Chen C, Moore D, Vazquez A, Harris S, Toppmeyer D, Levine A, Hirshfield KM. Abstract 681: Prognostic role of Perp in breast cancer Cancer Research. 72: 681-681. DOI: 10.1158/1538-7445.Am2012-681 |
0.285 |
|
2002 |
Pugacheva EN, Ivanov AV, Kravchenko JE, Kopnin BP, Levine AJ, Chumakov PM. Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil. Oncogene. 21: 4595-600. PMID 12096336 DOI: 10.1038/sj.onc.1205704 |
0.285 |
|
1998 |
Zeng X, Levine AJ, Lu H. Non-p53 p53RE binding protein, a human transcription factor functionally analogous to P53. Proceedings of the National Academy of Sciences of the United States of America. 95: 6681-6. PMID 9618472 DOI: 10.1073/pnas.95.12.6681 |
0.284 |
|
1974 |
Gallo RC, Levine A. Tumor viruses at Cold Spring Harbor. Cell. 2: 295-304. PMID 4370527 DOI: 10.1016/0092-8674(74)90024-5 |
0.283 |
|
2010 |
Hu W, Feng Z, Modica I, Klimstra DS, Song L, Allen PJ, Brennan MF, Levine AJ, Tang LH. Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway. Genes & Cancer. 1: 360-368. PMID 20871795 DOI: 10.1177/1947601910371979 |
0.282 |
|
1993 |
Perry ME, Levine AJ. Tumor-suppressor p53 and the cell cycle Current Opinion in Genetics and Development. 3: 50-54. PMID 8453275 DOI: 10.1016/S0959-437X(05)80340-5 |
0.282 |
|
1993 |
Zambetti GP, Levine AJ. A comparison of the biological activities of wild-type and mutant p53 Faseb Journal. 7: 855-865. PMID 8344485 DOI: 10.1096/fasebj.7.10.8344485 |
0.281 |
|
2015 |
Levine AJ, Chan CS, Dudgeon C, Puzio-Kuter A, Hainaut P. The Evolution of Tumors in Mice and Humans with Germline p53 Mutations. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26642854 DOI: 10.1101/sqb.2015.80.027631 |
0.28 |
|
2000 |
Strano S, Munarriz E, Rossi M, Cristofanelli B, Shaul Y, Castagnoli L, Levine AJ, Sacchi A, Cesareni G, Oren M, Blandino G. Physical and functional interaction between p53 mutants and different isoforms of p73. The Journal of Biological Chemistry. 275: 29503-12. PMID 10884390 DOI: 10.1074/Jbc.M003360200 |
0.28 |
|
2005 |
Arva NC, Gopen TR, Talbott KE, Campbell LE, Chicas A, White DE, Bond GL, Levine AJ, Bargonetti J. A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells. The Journal of Biological Chemistry. 280: 26776-87. PMID 15908423 DOI: 10.1074/Jbc.M505203200 |
0.28 |
|
1997 |
Walker KK, Levine AJ. Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proceedings of the National Academy of Sciences of the United States of America. 93: 15335-40. PMID 8986812 DOI: 10.1073/pnas.93.26.15335 |
0.278 |
|
2017 |
Baugh EH, Ke H, Levine AJ, Bonneau RA, Chan CS. Why are there hotspot mutations in the TP53 gene in human cancers? Cell Death and Differentiation. PMID 29099487 DOI: 10.1038/Cdd.2017.180 |
0.278 |
|
1998 |
Notterman D, Young S, Wainger B, Levine AJ. Prevention of mammalian DNA reduplication, following the release from the mitotic spindle checkpoint, requires p53 protein, but not p53-mediated transcriptional activity. Oncogene. 17: 2743-51. PMID 9840938 DOI: 10.1038/Sj.Onc.1202210 |
0.278 |
|
1997 |
Murphy M, Hinman A, Levine AJ. Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes & Development. 10: 2971-80. PMID 8956998 DOI: 10.1101/gad.10.23.2971 |
0.277 |
|
2009 |
Riley T, Yu X, Sontag E, Levine A. The p53HMM algorithm: using profile hidden markov models to detect p53-responsive genes. Bmc Bioinformatics. 10: 111. PMID 19379484 DOI: 10.1186/1471-2105-10-111 |
0.277 |
|
2006 |
Yu X, Harris SL, Levine AJ. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Research. 66: 4795-801. PMID 16651434 DOI: 10.1158/0008-5472.CAN-05-4579 |
0.277 |
|
1993 |
Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C, Levine AJ. Gain of function mutations in p53. Nature Genetics. 4: 42-6. PMID 8099841 DOI: 10.1038/ng0593-42 |
0.276 |
|
2009 |
Levine AJ, Oren M. The first 30 years of p53: growing ever more complex. Nature Reviews. Cancer. 9: 749-58. PMID 19776744 DOI: 10.1038/Nrc2723 |
0.275 |
|
1993 |
Wu X, Bayle JH, Olson D, Levine AJ. The p53-mdm-2 autoregulatory feedback loop. Genes & Development. 7: 1126-32. PMID 8319905 DOI: 10.1101/gad.7.7a.1126 |
0.275 |
|
2017 |
Levine AJ. The p53 protein plays a central role in the mechanism of action of epigentic drugs that alter the methylation of cytosine residues in DNA. Oncotarget. PMID 28129641 DOI: 10.18632/oncotarget.14805 |
0.275 |
|
1992 |
Moore M, Teresky AK, Levine AJ, Seiberg M. p53 mutations are not selected for in simian virus 40 T-antigen-induced tumors from transgenic mice. Journal of Virology. 66: 641-9. PMID 1370552 DOI: 10.1128/jvi.66.2.641-649.1992 |
0.274 |
|
2002 |
Singh B, Reddy PG, Goberdhan A, Walsh C, Dao S, Ngai I, Chou TC, O-Charoenrat P, Levine AJ, Rao PH, Stoffel A. p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas. Genes & Development. 16: 984-93. PMID 11959846 DOI: 10.1101/gad.973602 |
0.273 |
|
2018 |
Baugh EH, Ke H, Levine AJ, Bonneau RA, Chan CS. Why are there hotspot mutations in the TP53 gene in human cancers? Cell Death and Differentiation. 25: 154-160. PMID 31745308 DOI: 10.1038/cdd.2017.180 |
0.273 |
|
2017 |
Wong C, Clausen R, Tang L, Davidson C, Vosburgh E, Levine A, Xu E. Abstract 1538: A mouse model that mimics human MEN1 tumor is effective in preclinical neuroendocrine tumor therapeutics Cancer Research. 77: 1538-1538. DOI: 10.1158/1538-7445.Am2017-1538 |
0.273 |
|
1998 |
Roth J, Dobbelstein M, Freedman DA, Shenk T, Levine AJ. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. The Embo Journal. 17: 554-64. PMID 9430646 DOI: 10.1093/emboj/17.2.554 |
0.272 |
|
1993 |
Perry ME, Piette J, Zawadzki JA, Harvey D, Levine AJ. The mdm-2 gene is induced in response to UV light in a p53-dependent manner Proceedings of the National Academy of Sciences of the United States of America. 90: 11623-11627. PMID 8265599 DOI: 10.1073/pnas.90.24.11623 |
0.271 |
|
1992 |
Zambetti GP, Bargonetti J, Walker K, Prives C, Levine AJ. Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element Genes and Development. 6: 1143-1152. PMID 1628822 DOI: 10.1101/Gad.6.7.1143 |
0.269 |
|
2004 |
Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Arva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P, Onel K, Yip L, Hwang SJ, Strong LC, Lozano G, ... Levine AJ, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell. 119: 591-602. PMID 15550242 DOI: 10.1016/J.Cell.2004.11.022 |
0.267 |
|
2012 |
Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, ... ... Levine AJ, et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell. 148: 244-58. PMID 22265415 DOI: 10.1016/J.Cell.2011.12.017 |
0.265 |
|
1999 |
Freedman DA, Wu L, Levine AJ. Functions of the MDM2 oncoprotein. Cellular and Molecular Life Sciences : Cmls. 55: 96-107. PMID 10065155 DOI: 10.1007/s000180050273 |
0.265 |
|
1994 |
Cordon-Cardo C, Latres E, Drobnjak M, Oliva MR, Pollack D, Woodruff JM, Marechal V, Chen J, Brennan MF, Levine AJ. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Research. 54: 794-9. PMID 8306343 |
0.265 |
|
2000 |
Zhao R, Gish K, Murphy M, Yin Y, Notterman D, Hoffman WH, Tom E, Mack DH, Levine AJ. Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes & Development. 14: 981-93. PMID 10783169 |
0.265 |
|
2021 |
Levine AJ. Spontaneous and inherited TP53 genetic alterations. Oncogene. PMID 34389799 DOI: 10.1038/s41388-021-01991-3 |
0.264 |
|
2005 |
Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene. 24: 2899-908. PMID 15838523 DOI: 10.1038/sj.onc.1208615 |
0.264 |
|
2012 |
Yi L, Lu C, Hu W, Sun Y, Levine AJ. Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation. Cancer Research. 72: 5635-45. PMID 22964580 DOI: 10.1158/0008-5472.CAN-12-1451 |
0.263 |
|
2014 |
Dudgeon C, Chan C, Kang W, Sun Y, Emerson R, Robins H, Levine AJ. The evolution of thymic lymphomas in p53 knockout mice. Genes & Development. 28: 2613-20. PMID 25452272 DOI: 10.1101/Gad.252148.114 |
0.263 |
|
1995 |
Grand RJA, Lecane PS, Owen D, Grant ML, Roberts S, Levine AJ, Gallimore PH. The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression Virology. 210: 323-334. PMID 7618270 DOI: 10.1006/viro.1995.1349 |
0.263 |
|
1999 |
Blandino G, Levine AJ, Oren M. Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene. 18: 477-85. PMID 9927204 DOI: 10.1038/Sj.Onc.1202314 |
0.262 |
|
1996 |
Chen J, Wu X, Lin J, Levine AJ. mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Molecular and Cellular Biology. 16: 2445-52. PMID 8628312 DOI: 10.1128/MCB.16.5.2445 |
0.262 |
|
1998 |
Epstein CB, Attiyeh EF, Hobson DA, Silver AL, Broach JR, Levine AJ. p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors. Oncogene. 16: 2115-22. PMID 9572492 DOI: 10.1038/Sj.Onc.1201734 |
0.259 |
|
2006 |
Feng Z, Jin S, Zupnick A, Hoh J, de Stanchina E, Lowe S, Prives C, Levine AJ. p53 tumor suppressor protein regulates the levels of huntingtin gene expression. Oncogene. 25: 1-7. PMID 16278683 DOI: 10.1038/Sj.Onc.1209021 |
0.259 |
|
1995 |
Weinberg WC, Azzoli CG, Chapman K, Levine AJ, Yuspa SH. p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein. Oncogene. 10: 2271-9. PMID 7784075 |
0.257 |
|
2010 |
Jeong BS, Hu W, Belyi V, Rabadan R, Levine AJ. Differential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1347-53. PMID 20019240 DOI: 10.1096/Fj.09-146001 |
0.256 |
|
1990 |
Hinds PW, Finlay CA, Quartin RS, Baker SJ, Fearon ER, Vogelstein B, Levine AJ. Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes Cell Growth &Amp; Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 1: 571-580. PMID 2288874 |
0.255 |
|
2019 |
Levine AJ. Targeting Therapies for the p53 Protein in Cancer Treatments Annual Review of Cancer Biology. 3: 21-34. DOI: 10.1146/annurev-cancerbio-030518-055455 |
0.255 |
|
1999 |
Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ, George DL. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes & Development. 13: 2490-501. PMID 10521394 DOI: 10.1101/Gad.13.19.2490 |
0.255 |
|
1978 |
Holland JJ, Levine A. Mechanisms of viral persistence Cell. 14: 447-452. DOI: 10.1016/0092-8674(78)90130-7 |
0.254 |
|
1990 |
Levine AJ. The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses Virology. 177: 419-426. PMID 2142553 DOI: 10.1016/0042-6822(90)90505-L |
0.254 |
|
2005 |
Bond GL, Hu W, Levine AJ. MDM2 is a central node in the p53 pathway: 12 years and counting. Current Cancer Drug Targets. 5: 3-8. PMID 15720184 |
0.254 |
|
1994 |
Quartin RS, Cole CN, Pipas JM, Levine AJ. The amino-terminal functions of the simian virus 40 large T antigen are required to overcome wild-type p53-mediated growth arrest of cells Journal of Virology. 68: 1334-1341. PMID 8107198 DOI: 10.1128/Jvi.68.3.1334-1341.1994 |
0.252 |
|
1995 |
Chen J, Lin J, Levine AJ. Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Molecular Medicine (Cambridge, Mass.). 1: 142-52. PMID 8529093 |
0.249 |
|
2002 |
Hoh J, Jin S, Parrado T, Edington J, Levine AJ, Ott J. The p53MH algorithm and its application in detecting p53-responsive genes. Proceedings of the National Academy of Sciences of the United States of America. 99: 8467-72. PMID 12077306 DOI: 10.1073/Pnas.132268899 |
0.249 |
|
2015 |
Blanden AR, Yu X, Loh SN, Levine AJ, Carpizo DR. Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer. Drug Discovery Today. PMID 26205328 DOI: 10.1016/J.Drudis.2015.07.006 |
0.248 |
|
2000 |
Lev Bar-Or R, Maya R, Segel LA, Alon U, Levine AJ, Oren M. Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study. Proceedings of the National Academy of Sciences of the United States of America. 97: 11250-5. PMID 11016968 DOI: 10.1073/Pnas.210171597 |
0.248 |
|
1986 |
Lupton S, Levine AJ. Mapping genetic elements of Epstein-Barr virus that facilitate extrachromosomal persistence of Epstein-Barr virus-derived plasmids in human cells. Molecular and Cellular Biology. 5: 2533-42. PMID 3016506 DOI: 10.1128/mcb.5.10.2533-2542.1985 |
0.247 |
|
2013 |
Formosa A, Lena AM, Markert EK, Cortelli S, Miano R, Mauriello A, Croce N, Vandesompele J, Mestdagh P, Finazzi-Agrò E, Levine AJ, Melino G, Bernardini S, Candi E. DNA methylation silences miR-132 in prostate cancer. Oncogene. 32: 127-34. PMID 22310291 DOI: 10.1038/Onc.2012.14 |
0.247 |
|
2009 |
Levine AJ. The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53. Virology. 384: 285-93. PMID 19081592 DOI: 10.1016/j.virol.2008.09.034 |
0.247 |
|
1995 |
Wu L, Henri Bayle J, Elenbaas B, Pavletich NP, Levine AJ. Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids Molecular and Cellular Biology. 15: 497-504. PMID 7528329 |
0.247 |
|
2020 |
Levine AJ. p53: 800 million years of evolution and 40 years of discovery. Nature Reviews. Cancer. PMID 32404993 DOI: 10.1038/s41568-020-0262-1 |
0.246 |
|
2008 |
Feng Z, Hu W, Rajagopal G, Levine AJ. The tumor suppressor p53: cancer and aging. Cell Cycle (Georgetown, Tex.). 7: 842-7. PMID 18414039 |
0.245 |
|
1995 |
Lu H, Levine AJ. Human TAFII31 protein is a transcriptional coactivator of the p53 protein. Proceedings of the National Academy of Sciences of the United States of America. 92: 5154-8. PMID 7761466 DOI: 10.1073/pnas.92.11.5154 |
0.245 |
|
1993 |
Olson DC, Marechal V, Momand J, Chen J, Romocki C, Levine AJ. Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes. Oncogene. 8: 2353-60. PMID 7689721 |
0.245 |
|
2020 |
Levine AJ. P53 and The Immune Response: 40 Years of Exploration-A Plan for the Future. International Journal of Molecular Sciences. 21. PMID 31952115 DOI: 10.3390/ijms21020541 |
0.244 |
|
1997 |
Wu L, Levine AJ. Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene. Molecular Medicine (Cambridge, Mass.). 3: 441-51. PMID 9260156 |
0.244 |
|
2016 |
Chillemi G, Kehrloesser S, Bernassola F, Desideri A, Dötsch V, Levine AJ, Melino G. Structural Evolution and Dynamics of the p53 Proteins. Cold Spring Harbor Perspectives in Medicine. PMID 27091942 DOI: 10.1101/Cshperspect.A028308 |
0.244 |
|
2017 |
Levine AJ, Berger SL. The interplay between epigenetic changes and the p53 protein in stem cells. Genes & Development. 31: 1195-1201. PMID 28765161 DOI: 10.1101/Gad.298984.117 |
0.243 |
|
2014 |
Lukic S, Nicolas JC, Levine AJ. The diversity of zinc-finger genes on human chromosome 19 provides an evolutionary mechanism for defense against inherited endogenous retroviruses. Cell Death and Differentiation. 21: 381-7. PMID 24162661 DOI: 10.1038/cdd.2013.150 |
0.242 |
|
2009 |
Atwal GS, Kirchhoff T, Bond EE, Montagna M, Monagna M, Menin C, Bertorelle R, Scaini MC, Bartel F, Böhnke A, Pempe C, Gradhand E, Hauptmann S, Offit K, Levine AJ, et al. Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene. Proceedings of the National Academy of Sciences of the United States of America. 106: 10236-41. PMID 19497887 DOI: 10.1073/Pnas.0901298106 |
0.241 |
|
1989 |
Finlay CA, Hinds PW, Levine AJ. The p53 proto-oncogene can act as a suppressor of transformation Cell. 57: 1083-1093. PMID 2525423 DOI: 10.1016/0092-8674(89)90045-7 |
0.241 |
|
2008 |
Vazquez A, Bond EE, Levine AJ, Bond GL. The genetics of the p53 pathway, apoptosis and cancer therapy. Nature Reviews. Drug Discovery. 7: 979-87. PMID 19043449 DOI: 10.1038/nrd2656 |
0.241 |
|
2011 |
Zhang C, Lin M, Wu R, Wang X, Yang B, Levine AJ, Hu W, Feng Z. Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proceedings of the National Academy of Sciences of the United States of America. 108: 16259-64. PMID 21930938 DOI: 10.1073/pnas.1113884108 |
0.241 |
|
1998 |
Freedman DA, Levine AJ. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Molecular and Cellular Biology. 18: 7288-93. PMID 9819415 DOI: 10.1128/MCB.18.12.7288 |
0.241 |
|
1991 |
Harvey DM, Levine AJ. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes & Development. 5: 2375-85. PMID 1752433 DOI: 10.1101/gad.5.12b.2375 |
0.241 |
|
2010 |
Mizuno H, Spike BT, Wahl GM, Levine AJ. Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures. Proceedings of the National Academy of Sciences of the United States of America. 107: 22745-50. PMID 21149740 DOI: 10.1073/Pnas.1017001108 |
0.24 |
|
1994 |
Lin J, Chen J, Elenbaas B, Levine AJ. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. Genes & Development. 8: 1235-46. PMID 7926727 DOI: 10.1101/gad.8.10.1235 |
0.239 |
|
2005 |
Ma L, Wagner J, Rice JJ, Hu W, Levine AJ, Stolovitzky GA. A plausible model for the digital response of p53 to DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 102: 14266-71. PMID 16186499 DOI: 10.1073/pnas.0501352102 |
0.238 |
|
1976 |
Levinson A, Levine AJ, Anderson S, Osborn M, Rosenwirth B, Weber K. The relationship between group C adenovirus tumor antigen and the adenovirus single-strand DNA-binding protein. Cell. 7: 575-84. PMID 782721 DOI: 10.1016/0092-8674(76)90208-7 |
0.237 |
|
2004 |
Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genetics. 36: 147-50. PMID 14730303 DOI: 10.1038/Ng1293 |
0.237 |
|
1989 |
Hinds P, Finlay C, Levine AJ. Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. Journal of Virology. 63: 739-746. DOI: 10.1128/Jvi.63.2.739-746.1989 |
0.237 |
|
2015 |
D'Abramo M, Bešker N, Desideri A, Levine AJ, Melino G, Chillemi G. The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain. Oncogene. PMID 26477317 DOI: 10.1038/onc.2015.388 |
0.237 |
|
1989 |
Hinds P, Finlay C, Levine AJ. Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. Journal of Virology. 63: 739-46. PMID 2642977 DOI: 10.1128/JVI.63.2.739-746.1989 |
0.237 |
|
1992 |
Moll UM, Riou G, Levine AJ. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proceedings of the National Academy of Sciences of the United States of America. 89: 7262-6. PMID 1353891 DOI: 10.1073/pnas.89.15.7262 |
0.236 |
|
1995 |
Lin J, Teresky AK, Levine AJ. Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants. Oncogene. 10: 2387-90. PMID 7784087 |
0.236 |
|
2004 |
Stoffel A, Chaurushiya M, Singh B, Levine AJ. Activation of NF-kappaB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 9079-84. PMID 15184680 DOI: 10.1073/pnas.0402415101 |
0.234 |
|
1982 |
Oren M, Reich NC, Levine AJ. Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny Molecular and Cellular Biology. 2: 443-449. PMID 6287239 DOI: 10.1128/mcb.2.4.443-449.1982 |
0.233 |
|
1994 |
Olson DC, Levine AJ. The properties of p53 proteins selected for the loss of suppression of transformation. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 5: 61-71. PMID 8123594 |
0.233 |
|
2009 |
Yu X, Riley T, Levine AJ. The regulation of the endosomal compartment by p53 the tumor suppressor gene. The Febs Journal. 276: 2201-12. PMID 19302216 DOI: 10.1111/J.1742-4658.2009.06949.X |
0.233 |
|
2010 |
Hirshfield KM, Rebbeck TR, Levine AJ. Germline mutations and polymorphisms in the origins of cancers in women. Journal of Oncology. 2010: 297671. PMID 20111735 DOI: 10.1155/2010/297671 |
0.233 |
|
1981 |
Sekikawa K, Levine AJ. Isolation and characterization of polyoma host range mutants that replicate in nullipotential embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 1100-4. PMID 6262755 DOI: 10.1073/PNAS.78.2.1100 |
0.233 |
|
1976 |
Levine AJ, van der Vliet PC, Rosenwirth B, Anderson C, Rabek J, Levinson A, Anderson S. Characterization of an adenovirus early protein required for viral DNA replication: a single strand specific DNA binding proteins. Molecular and Cellular Biochemistry. 11: 79-95. PMID 178993 DOI: 10.1007/BF01792789 |
0.232 |
|
2016 |
Levine AJ, Puzio-Kuter AM, Chan CS, Hainaut P. The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation. Cold Spring Harbor Perspectives in Medicine. PMID 27352800 DOI: 10.1101/cshperspect.a026153 |
0.232 |
|
1970 |
Ritzi E, Levine AJ. Deoxyribonucleic acid replication in simian virus 40-infected cells. 3. Comparison of simian virus 40 lytic infection in three different monkey kidney cell lines. Journal of Virology. 5: 686-92. PMID 4317114 DOI: 10.1128/jvi.5.6.686-692.1970 |
0.232 |
|
2001 |
Pipas JM, Levine AJ. Role of T antigen interactions with p53 in tumorigenesis. Seminars in Cancer Biology. 11: 23-30. PMID 11243896 DOI: 10.1006/Scbi.2000.0343 |
0.231 |
|
2020 |
Rabadán R, Mohamedi Y, Rubin U, Chu T, Alghalith AN, Elliott O, Arnés L, Cal S, Obaya ÁJ, Levine AJ, Cámara PG. Identification of relevant genetic alterations in cancer using topological data analysis. Nature Communications. 11: 3808. PMID 32732999 DOI: 10.1038/S41467-020-17659-7 |
0.231 |
|
1983 |
Reich NC, Oren M, Levine AJ. Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53 Molecular and Cellular Biology. 3: 2143-2150. PMID 6318085 DOI: 10.1128/mcb.3.12.2143-2150.1983 |
0.231 |
|
2003 |
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15077-82. PMID 14657337 DOI: 10.1073/Pnas.2436255100 |
0.23 |
|
1984 |
Thomas R, Kaplan L, Reich N, Lane DP, Levine AJ. Characterization of human p53 antigens employing primate specific monoclonal antibodies. Virology. 131: 502-17. PMID 6318442 DOI: 10.1016/0042-6822(83)90516-0 |
0.23 |
|
1991 |
Chittenden T, Frey A, Levine AJ. Regulated replication of an episomal simian virus 40 origin plasmid in COS7 cells. Journal of Virology. 65: 5944-5951. PMID 1656081 DOI: 10.1128/Jvi.65.11.5944-5951.1991 |
0.229 |
|
2004 |
Stoffel A, Levine AJ. Actvation of NF-kappaB by the API2/MALT1 fusions inhibits p53 dependant but not FAS induced apoptosis: a directional link between NF-kappaB and p53. Cell Cycle (Georgetown, Tex.). 3: 1017-20. PMID 15280657 |
0.229 |
|
2012 |
Hu W, Feng Z, Levine AJ. The Regulation of Multiple p53 Stress Responses is Mediated through MDM2. Genes & Cancer. 3: 199-208. PMID 23150753 DOI: 10.1177/1947601912454734 |
0.228 |
|
1991 |
Oh S, Chittenden T, Levine AJ. Identification of cellular factors that bind specifically to the Epstein-Barr virus origin of DNA replication. Journal of Virology. 65: 514-519. PMID 1845905 DOI: 10.1128/Jvi.65.1.514-519.1991 |
0.228 |
|
2001 |
Sablina AA, Chumakov PM, Levine AJ, Kopnin BP. p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling. Oncogene. 20: 899-909. PMID 11314025 DOI: 10.1038/sj.onc.1204156 |
0.228 |
|
2006 |
Levine AJ, Hu W, Feng Z. The P53 pathway: what questions remain to be explored? Cell Death and Differentiation. 13: 1027-36. PMID 16557269 DOI: 10.1038/sj.cdd.4401910 |
0.228 |
|
2010 |
Ak P, Levine AJ. p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3643-52. PMID 20530750 DOI: 10.1096/fj.10-160549 |
0.228 |
|
1993 |
Rotter V, Schwartz D, Almon E, Goldfinger N, Kapon A, Meshorer A, Donehower LA, Levine AJ. Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome. Proceedings of the National Academy of Sciences of the United States of America. 90: 9075-9. PMID 8415656 DOI: 10.1073/Pnas.90.19.9075 |
0.227 |
|
1990 |
Werness BA, Levine AJ, Howley PM. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (New York, N.Y.). 248: 76-9. PMID 2157286 DOI: 10.1126/Science.2157286 |
0.227 |
|
1982 |
Reich NC, Levine AJ. Specific interaction of the SV40 T antigen-cellular p53 protein complex with SV40 DNA Virology. 117: 286-290. PMID 6278740 DOI: 10.1016/0042-6822(82)90531-1 |
0.226 |
|
1997 |
Elenbaas B, Dobbelstein M, Roth J, Shenk T, Levine AJ. The MDM2 oncoprotein binds specifically to RNA through its RING finger domain. Molecular Medicine (Cambridge, Mass.). 2: 439-51. PMID 8827714 |
0.226 |
|
1971 |
Kang HS, Eshbach TB, White DA, Levine AJ. Deoxyribonucleic acid replication in simian virus 40-infected cells. IV. Two different requirements for protein synthesis during simian virus 40 deoxyribonucleic acid replication. Journal of Virology. 7: 112-20. PMID 5543424 DOI: 10.1128/jvi.7.1.112-120.1971 |
0.225 |
|
2005 |
Wagner J, Ma L, Rice JJ, Hu W, Levine AJ, Stolovitzky GA. p53-Mdm2 loop controlled by a balance of its feedback strength and effective dampening using ATM and delayed feedback. Systems Biology. 152: 109-18. PMID 16986275 DOI: 10.1049/ip-syb:20050025 |
0.225 |
|
1998 |
Theobald M, Ruppert T, Kuckelkorn U, Hernandez J, Häussler A, Ferreira EA, Liewer U, Biggs J, Levine AJ, Huber C, Koszinowski UH, Kloetzel PM, Sherman LA. The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope. The Journal of Experimental Medicine. 188: 1017-28. PMID 9743520 DOI: 10.1084/jem.188.6.1017 |
0.225 |
|
2010 |
Post SM, Quintás-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G. A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development. Cancer Cell. 18: 220-30. PMID 20832750 DOI: 10.1016/J.Ccr.2010.07.010 |
0.225 |
|
1989 |
Marks J, Lin J, Miller D, Lozano G, Herbert J, Levine AJ. The expression of viral and cellular genes in papillomas of the choroid plexus induced in transgenic mice. Progress in Clinical and Biological Research. 284: 163-86. PMID 2851142 |
0.224 |
|
2023 |
Levine AJ, Carpten JD, Murphy M, Hainaut P. Exploring the genetic and molecular basis of differences in multiple myeloma of individuals of African and European descent. Cell Death and Differentiation. PMID 38001255 DOI: 10.1038/s41418-023-01236-8 |
0.222 |
|
1997 |
Chen L, Marechal V, Moreau J, Levine AJ, Chen J. Proteolytic cleavage of the mdm2 oncoprotein during apoptosis. The Journal of Biological Chemistry. 272: 22966-73. PMID 9278461 DOI: 10.1074/jbc.272.36.22966 |
0.222 |
|
1995 |
Del Sal G, Ruaro EM, Utrera R, Cole CN, Levine AJ, Schneider C. Gas1-induced growth suppression requires a transactivation-independent p53 function Molecular and Cellular Biology. 15: 7152-7160. PMID 8524283 DOI: 10.1128/Mcb.15.12.7152 |
0.221 |
|
2008 |
Hu W, Feng Z, Atwal GS, Levine AJ. p53: a new player in reproduction. Cell Cycle (Georgetown, Tex.). 7: 848-52. PMID 18414047 |
0.221 |
|
1999 |
Casau AE, Vaughan JE, Lozano G, Levine AJ. Germ cell expression of an isolated human endogenous retroviral long terminal repeat of the HERV-K/HTDV family in transgenic mice. Journal of Virology. 73: 9976-83. PMID 10559311 DOI: 10.1128/Jvi.73.12.9976-9983.1999 |
0.221 |
|
1985 |
Hearing JC, Levine AJ. The Epstein-Barr virus nuclear antigen (BamHI K antigen) is a single-stranded DNA binding phosphoprotein. Virology. 145: 105-16. PMID 2990095 DOI: 10.1016/0042-6822(85)90205-3 |
0.221 |
|
1995 |
Chen J, Lin J, Levine AJ. Regulation of Transcription Functions of the p53 Tumor Suppressor by the mdm-2 Oncogene Molecular Medicine. 1: 142-152. DOI: 10.1007/BF03401562 |
0.22 |
|
2001 |
Berger M, Vogt Sionov R, Levine AJ, Haupt Y. A role for the polyproline domain of p53 in its regulation by Mdm2. The Journal of Biological Chemistry. 276: 3785-90. PMID 11053443 DOI: 10.1074/jbc.M008879200 |
0.219 |
|
2014 |
Huang Q, Yu L, Levine AJ, Nussinov R, Ma B. Dipeptide analysis of p53 mutations and evolution of p53 family proteins. Biochimica Et Biophysica Acta. 1844: 198-206. PMID 23583620 DOI: 10.1016/J.Bbapap.2013.04.002 |
0.219 |
|
2009 |
Grochola LF, Vazquez A, Bond EE, Würl P, Taubert H, Müller TH, Levine AJ, Bond GL. Recent natural selection identifies a genetic variant in a regulatory subunit of protein phosphatase 2A that associates with altered cancer risk and survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6301-8. PMID 19773383 DOI: 10.1158/1078-0432.CCR-09-0797 |
0.219 |
|
1989 |
Seiberg M, Aloni Y, Levine AJ. Comparison of human and monkey cells for the ability to attenuate transcripts that begin at the adenovirus major late promoter. Journal of Virology. 63: 4093-6. PMID 2503624 DOI: 10.1128/jvi.63.9.4093-4096.1989 |
0.219 |
|
1986 |
Tan TH, Wallis J, Levine AJ. Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex. Journal of Virology. 59: 574-83. PMID 3016321 DOI: 10.1128/jvi.59.3.574-583.1986 |
0.218 |
|
1988 |
Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life Molecular and Cellular Biology. 8: 531-539. PMID 2832726 DOI: 10.1128/mcb.8.2.531-539.1988 |
0.218 |
|
1982 |
Nicolas JC, Ingrand D, Sarnow P, Levine AJ. A mutation in the adenovirus type 5 DNA binding protein that fails to autoregulate the production of the DNA binding protein. Virology. 122: 481-5. PMID 6815890 DOI: 10.1016/0042-6822(82)90249-5 |
0.218 |
|
2004 |
Levine AJ, Finlay CA, Hinds PW. P53 is a tumor suppressor gene. Cell. 116: S67-9, 1 p following. PMID 15055586 DOI: 10.1016/S0092-8674(04)00036-4 |
0.218 |
|
1994 |
Levine AJ, Chang A, Dittmer D, Notterman DA, Silver A, Thorn K, Welsh D, Wu M. The p53 tumor suppressor gene. The Journal of Laboratory and Clinical Medicine. 123: 817-23. PMID 8201258 |
0.218 |
|
1992 |
Levine AJ. The p53 tumor-suppressor gene. The New England Journal of Medicine. 326: 1350-2. PMID 1565147 DOI: 10.1056/NEJM199205143262008 |
0.218 |
|
1984 |
Reich NC, Levine AJ. Growth regulation of a cellular tumour antigen, p53, in nontransformed cells Nature. 308: 199-201. PMID 6366574 DOI: 10.1038/308199a0 |
0.217 |
|
2013 |
Zhang C, Liu J, Liang Y, Wu R, Zhao Y, Hong X, Lin M, Yu H, Liu L, Levine AJ, Hu W, Feng Z. Tumour-associated mutant p53 drives the Warburg effect. Nature Communications. 4: 2935. PMID 24343302 DOI: 10.1038/ncomms3935 |
0.216 |
|
1999 |
Tao W, Levine AJ. Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proceedings of the National Academy of Sciences of the United States of America. 96: 3077-80. PMID 10077639 DOI: 10.1073/pnas.96.6.3077 |
0.216 |
|
1997 |
Ruaro EM, Collavin L, Del Sal G, Haffner R, Oren M, Levine AJ, Schneider C. A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1. Proceedings of the National Academy of Sciences of the United States of America. 94: 4675-80. PMID 9114050 DOI: 10.1073/Pnas.94.9.4675 |
0.216 |
|
1991 |
Shaulsky G, Goldfinger N, Tosky MS, Levine AJ, Rotter V. Nuclear localization is essential for the activity of p53 protein Oncogene. 6: 2055-2065. PMID 1719467 |
0.216 |
|
1995 |
Sabbatini P, Lin J, Levine AJ, White E. Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes & Development. 9: 2184-92. PMID 7657169 DOI: 10.1101/gad.9.17.2184 |
0.215 |
|
1998 |
Lu H, Taya Y, Ikeda M, Levine AJ. Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389. Proceedings of the National Academy of Sciences of the United States of America. 95: 6399-402. PMID 9600977 DOI: 10.1073/pnas.95.11.6399 |
0.215 |
|
2010 |
Belyi VA, Ak P, Markert E, Wang H, Hu W, Puzio-Kuter A, Levine AJ. The origins and evolution of the p53 family of genes. Cold Spring Harbor Perspectives in Biology. 2: a001198. PMID 20516129 DOI: 10.1101/cshperspect.a001198 |
0.215 |
|
2010 |
Hu W, Chan CS, Wu R, Zhang C, Sun Y, Song JS, Tang LH, Levine AJ, Feng Z. Negative regulation of tumor suppressor p53 by microRNA miR-504. Molecular Cell. 38: 689-99. PMID 20542001 DOI: 10.1016/J.Molcel.2010.05.027 |
0.215 |
|
2010 |
Feng Z, Levine AJ. The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends in Cell Biology. 20: 427-34. PMID 20399660 DOI: 10.1016/j.tcb.2010.03.004 |
0.215 |
|
1995 |
Horikoshi N, Usheva A, Chen J, Levine AJ, Weinmann R, Shenk T. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Molecular and Cellular Biology. 15: 227-34. PMID 7799929 DOI: 10.1128/Mcb.15.1.227 |
0.213 |
|
1983 |
Levine AJ, Reich N, Thomas R. The regulation of a cellular protein, p53, in normal and transformed cells Progress in Clinical and Biological Research. 119: 159-169. PMID 6306685 |
0.213 |
|
2011 |
Levine AJ, Tomasini R, McKeon FD, Mak TW, Melino G. The p53 family: guardians of maternal reproduction. Nature Reviews. Molecular Cell Biology. 12: 259-65. PMID 21427767 DOI: 10.1038/nrm3086 |
0.213 |
|
2007 |
Feng Z, Hu W, de Stanchina E, Teresky AK, Jin S, Lowe S, Levine AJ. The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Research. 67: 3043-53. PMID 17409411 DOI: 10.1158/0008-5472.Can-06-4149 |
0.212 |
|
2007 |
Ma B, Levine AJ. Probing potential binding modes of the p53 tetramer to DNA based on the symmetries encoded in p53 response elements. Nucleic Acids Research. 35: 7733-47. PMID 17986463 DOI: 10.1093/nar/gkm890 |
0.212 |
|
1987 |
Hinds PW, Finlay CA, Frey AB, Levine AJ. Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines Molecular and Cellular Biology. 7: 2863-2869. PMID 3313006 DOI: 10.1128/mcb.7.8.2863-2869.1987 |
0.212 |
|
1993 |
Almon E, Goldfinger N, Kapon A, Schwartz D, Levine AJ, Rotter V. Testicular tissue-specific expression of the p53 suppressor gene Developmental Biology. 156: 107-116. PMID 7680625 DOI: 10.1006/Dbio.1993.1062 |
0.212 |
|
1994 |
Perry ME, Levine AJ. P53 and mdm-2: interactions between tumor suppressor gene and oncogene products Mount Sinai Journal of Medicine. 61: 291-299. PMID 7969222 |
0.212 |
|
2009 |
Kang HJ, Feng Z, Sun Y, Atwal G, Murphy ME, Rebbeck TR, Rosenwaks Z, Levine AJ, Hu W. Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans. Proceedings of the National Academy of Sciences of the United States of America. 106: 9761-6. PMID 19470478 DOI: 10.1073/pnas.0904280106 |
0.211 |
|
2012 |
Yu X, Vazquez A, Levine AJ, Carpizo DR. Allele-specific p53 mutant reactivation. Cancer Cell. 21: 614-25. PMID 22624712 DOI: 10.1016/J.Ccr.2012.03.042 |
0.211 |
|
2005 |
Feng Z, Zhang H, Levine AJ, Jin S. The coordinate regulation of the p53 and mTOR pathways in cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 8204-9. PMID 15928081 DOI: 10.1073/pnas.0502857102 |
0.209 |
|
1984 |
Nowak B, Gmeiner A, Sarnow P, Levine AJ, Fleckenstein B. Physical mapping of human cytomegalovirus genes: identification of DNA sequences coding for a virion phosphoprotein of 71 kDa and a viral 65-kDa polypeptide. Virology. 134: 91-102. PMID 6324477 DOI: 10.1016/0042-6822(84)90275-7 |
0.209 |
|
1990 |
Labow MA, Baim SB, Shenk T, Levine AJ. Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells Molecular and Cellular Biology. 10: 3343-3356. PMID 2162473 DOI: 10.1128/mcb.10.7.3343-3356.1990 |
0.209 |
|
1996 |
Theobald M, Biggs J, Dittmer D, Levine AJ, Sherman LA. Targeting p53 as a general tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 92: 11993-7. PMID 8618830 DOI: 10.1073/pnas.92.26.11993 |
0.209 |
|
2005 |
Ma B, Pan Y, Gunasekaran K, Keskin O, Venkataraghavan RB, Levine AJ, Nussinov R. The contribution of the Trp/Met/Phe residues to physical interactions of p53 with cellular proteins. Physical Biology. 2: S56-66. PMID 16204849 DOI: 10.1088/1478-3975/2/2/S06 |
0.209 |
|
1996 |
Del Sal G, Murphy M, Ruaro E, Lazarevic D, Levine AJ, Schneider C. Cyclin D1 and p21/waf1 are both involved in p53 growth suppression. Oncogene. 12: 177-85. PMID 8552389 |
0.209 |
|
1975 |
Levine AJ, Van Der Vliet PC, Rosenwirth B, Rabek J, Frenkel G, Ensinger M. Adenovirus-infected, cell-specific, DNA-binding proteins. Cold Spring Harbor Symposia On Quantitative Biology. 559-66. PMID 169091 DOI: 10.1101/SQB.1974.039.01.069 |
0.208 |
|
1974 |
van der Vliet PC, Levine AJ. DNA-binding proteins specific for cells infected by adenovirus. Nature: New Biology. 246: 170-4. PMID 4202226 DOI: 10.1038/NEWBIO246170A0 |
0.208 |
|
1991 |
Martinez J, Georgoff I, Martinez J, Levine AJ. Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes & Development. 5: 151-9. PMID 1995413 DOI: 10.1101/GAD.5.2.151 |
0.208 |
|
1993 |
Chen J, Marechal V, Levine AJ. Mapping of the p53 and mdm-2 interaction domains. Molecular and Cellular Biology. 13: 4107-14. PMID 7686617 DOI: 10.1128/mcb.13.7.4107-4114.1993 |
0.208 |
|
2014 |
Wong C, Laddha SV, Tang L, Vosburgh E, Levine AJ, Normant E, Sandy P, Harris CR, Chan CS, Xu EY. The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors. Cell Death & Disease. 5: e1450. PMID 25299775 DOI: 10.1038/cddis.2014.396 |
0.208 |
|
1992 |
Zambetti GP, Olson D, Labow M, Levine AJ. A mutant p53 protein is required for maintenance of the transformed phenotype in cells transformed with p53 plus ras cDNAs Proceedings of the National Academy of Sciences of the United States of America. 89: 3952-3956. PMID 1570319 DOI: 10.1073/pnas.89.9.3952 |
0.208 |
|
1997 |
Lu H, Fisher RP, Bailey P, Levine AJ. The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro. Molecular and Cellular Biology. 17: 5923-34. PMID 9315650 DOI: 10.1128/MCB.17.10.5923 |
0.207 |
|
1999 |
Tao W, Levine AJ. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 96: 6937-41. PMID 10359817 DOI: 10.1073/pnas.96.12.6937 |
0.207 |
|
1989 |
Marks JR, Lin J, Hinds P, Miller D, Levine AJ. Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen Journal of Virology. 63: 790-797. PMID 2642978 DOI: 10.1128/Jvi.63.2.790-797.1989 |
0.207 |
|
1988 |
Levine AJ. Oncogenes of DNA tumor viruses. Cancer Research. 48: 493-6. PMID 3275498 |
0.207 |
|
2011 |
Feng Z, Zhang C, Kang HJ, Sun Y, Wang H, Naqvi A, Frank AK, Rosenwaks Z, Murphy ME, Levine AJ, Hu W. Regulation of female reproduction by p53 and its family members. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2245-55. PMID 21402718 DOI: 10.1096/fj.10-180166 |
0.205 |
|
2012 |
Tang LH, Contractor T, Clausen R, Klimstra DS, Du YC, Allen PJ, Brennan MF, Levine AJ, Harris CR. Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4612-20. PMID 22761470 DOI: 10.1158/1078-0432.Ccr-11-3264 |
0.205 |
|
1989 |
Voelkerding KV, Sandhaus LM, Kim HC, Wilson J, Chittenden T, Levine AJ, Raska K. Plasma cell malignancy in the acquired immune deficiency syndrome. Association with Epstein-Barr virus. American Journal of Clinical Pathology. 92: 222-8. PMID 2547309 DOI: 10.1093/AJCP/92.2.222 |
0.204 |
|
1995 |
Lin J, Wu X, Chen J, Chang A, Levine AJ. Functions of the p53 protein in growth regulation and tumor suppression. Cold Spring Harbor Symposia On Quantitative Biology. 59: 215-23. PMID 7587073 DOI: 10.1101/SQB.1994.059.01.026 |
0.204 |
|
2017 |
Levine AJ. The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene. Current Topics in Microbiology and Immunology. PMID 28349284 DOI: 10.1007/82_2017_5 |
0.204 |
|
1994 |
Levine AJ. The origins of the small DNA tumor viruses Advances in Cancer Research. 65: 141-168. PMID 7879664 DOI: 10.1016/S0065-230X(08)60067-6 |
0.203 |
|
2007 |
Hu W, Feng Z, Ma L, Wagner J, Rice JJ, Stolovitzky G, Levine AJ. A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells. Cancer Research. 67: 2757-65. PMID 17363597 DOI: 10.1158/0008-5472.Can-06-2656 |
0.203 |
|
2014 |
Ariffin H, Hainaut P, Puzio-Kuter A, Choong SS, Chan AS, Tolkunov D, Rajagopal G, Kang W, Lim LL, Krishnan S, Chen KS, Achatz MI, Karsa M, Shamsani J, Levine AJ, et al. Whole-genome sequencing analysis of phenotypic heterogeneity and anticipation in Li-Fraumeni cancer predisposition syndrome. Proceedings of the National Academy of Sciences of the United States of America. 111: 15497-501. PMID 25313051 DOI: 10.1073/Pnas.1417322111 |
0.202 |
|
1998 |
Roth J, Dobbelstein M, Freedman D, Shenk T, Levine A. Nucleo-cytoplasmic shuttling of the HDM2 oncoprotein regulates the levels of P53 protein VIA a pathway USED by the human immunodeficiency virus REV protein Gastroenterology. 114: A669. DOI: 10.1016/S0016-5085(98)82742-X |
0.201 |
|
1990 |
Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 Cell. 63: 1129-1136. PMID 2175676 DOI: 10.1016/0092-8674(90)90409-8 |
0.201 |
|
1999 |
Zhang CC, Yang JM, Bash-Babula J, White E, Murphy M, Levine AJ, Hait WN. DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4. Cancer Research. 59: 3663-70. PMID 10446979 |
0.201 |
|
1994 |
Levine AJ. The road to the discovery of the p53 protein. The Steiner Cancer Prize Award Lecture. International Journal of Cancer. 56: 775-6. PMID 8119764 DOI: 10.1002/ijc.2910560602 |
0.2 |
|
1989 |
Wong KM, Levine AJ. Characterization of proteins encoded by the Epstein-Barr virus transactivator gene BMLF1. Virology. 168: 101-11. PMID 2535897 DOI: 10.1016/0042-6822(89)90408-X |
0.2 |
|
1984 |
Brinster RL, Chen HY, Messing A, van Dyke T, Levine AJ, Palmiter RD. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell. 37: 367-79. PMID 6327063 DOI: 10.1016/0092-8674(84)90367-2 |
0.2 |
|
1997 |
Wu L, Levine AJ. Differential Regulation of the p21/WAF-1 and mdm2 Genes after High-Dose UV Irradiation: p53-Dependent and p53-Independent Regulation of the mdm2 Gene Molecular Medicine. 3: 441-451. DOI: 10.1007/BF03401691 |
0.2 |
|
1991 |
Howley PM, Levine AJ, Li FP, Livingston DM, Rabson AS. Lack of SV40 DNA in tumors from scientists working with SV40 virus New England Journal of Medicine. 324: 494. PMID 1846436 DOI: 10.1056/NEJM199102143240716 |
0.199 |
|
1983 |
Oren M, Levine AJ. Molecular cloning of a cDNA specific for the murine p53 cellular tumor antigen Proceedings of the National Academy of Sciences of the United States of America. 80: 56-59. PMID 6296874 DOI: 10.1073/Pnas.80.1.56 |
0.199 |
|
1996 |
Lin J, Reichner C, Wu X, Levine AJ. Analysis of wild-type and mutant p21WAF-1 gene activities. Molecular and Cellular Biology. 16: 1786-93. PMID 8657154 DOI: 10.1128/MCB.16.4.1786 |
0.199 |
|
2006 |
Bond GL, Hirshfield KM, Kirchhoff T, Alexe G, Bond EE, Robins H, Bartel F, Taubert H, Wuerl P, Hait W, Toppmeyer D, Offit K, Levine AJ. MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner. Cancer Research. 66: 5104-10. PMID 16707433 DOI: 10.1158/0008-5472.Can-06-0180 |
0.199 |
|
1970 |
Levine AJ, Teresky AK. Deoxyribonucleic acid replication in simian virus 40-infected cells. II. Detection and characterization of simian virus 40 pseudovirions. Journal of Virology. 5: 451-7. PMID 4318087 DOI: 10.1128/jvi.5.4.451-457.1970 |
0.199 |
|
1993 |
Levine AJ. 11th Ernst Klenk Lecture. The p53 tumor suppressor gene and product Biological Chemistry Hoppe-Seyler. 374: 227-235. PMID 8329141 |
0.198 |
|
2008 |
Atwal GS, Rabadán R, Lozano G, Strong LC, Ruijs MW, Schmidt MK, van't Veer LJ, Nevanlinna H, Tommiska J, Aittomäki K, Bougeard G, Frebourg T, Levine AJ, Bond GL. An information-theoretic analysis of genetics, gender and age in cancer patients. Plos One. 3: e1951. PMID 18398474 DOI: 10.1371/Journal.Pone.0001951 |
0.198 |
|
2014 |
Amelio I, Markert EK, Rufini A, Antonov AV, Sayan BS, Tucci P, Agostini M, Mineo TC, Levine AJ, Melino G. p73 regulates serine biosynthesis in cancer. Oncogene. 33: 5039-46. PMID 24186203 DOI: 10.1038/onc.2013.456 |
0.197 |
|
1986 |
Wong KM, Levine AJ. Identification and mapping of Epstein-Barr virus early antigens and demonstration of a viral gene activator that functions in trans. Journal of Virology. 60: 149-56. PMID 3018282 DOI: 10.1128/jvi.60.1.149-156.1986 |
0.196 |
|
1979 |
Segal S, Levine AJ, Khoury G. Evidence for non-spliced SV40 RNA in undifferentiated murine teratocarcinoma stem cells. Nature. 280: 335-338. PMID 223058 DOI: 10.1038/280335A0 |
0.196 |
|
1988 |
Clarke CF, Cheng K, Frey AB, Stein R, Hinds PW, Levine AJ. Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP Molecular and Cellular Biology. 8: 1206-1215. PMID 3285177 DOI: 10.1128/mcb.8.3.1206-1215.1988 |
0.195 |
|
1997 |
Freedman DA, Epstein CB, Roth JC, Levine AJ. A genetic approach to mapping the p53 binding site in the MDM2 protein. Molecular Medicine (Cambridge, Mass.). 3: 248-59. PMID 9131587 |
0.195 |
|
1971 |
Sheppard JR, Levine AJ, Burger MM. Cell-surface changes after infection with oncogenic viruses: requirement for synthesis of host DNA. Science (New York, N.Y.). 172: 1345-6. PMID 4325520 DOI: 10.1126/science.172.3990.1345 |
0.195 |
|
1983 |
Nicolas JC, Sarnow P, Girard M, Levine AJ. Host range temperature-conditional mutants in the adenovirus DNA binding protein are defective in the assembly of infectious virus. Virology. 126: 228-39. PMID 6302984 DOI: 10.1016/0042-6822(83)90474-9 |
0.194 |
|
2009 |
Harris CR, Dewan A, Zupnick A, Normart R, Gabriel A, Prives C, Levine AJ, Hoh J. p53 responsive elements in human retrotransposons. Oncogene. 28: 3857-65. PMID 19718052 DOI: 10.1038/Onc.2009.246 |
0.194 |
|
2022 |
Levine AJ. Targeting the P53 Protein for Cancer Therapies: The Translational Impact of P53 Research. Cancer Research. 82: 362-364. PMID 35110395 DOI: 10.1158/0008-5472.CAN-21-2709 |
0.194 |
|
2010 |
Belyi VA, Levine AJ, Skalka AM. Unexpected inheritance: multiple integrations of ancient bornavirus and ebolavirus/marburgvirus sequences in vertebrate genomes. Plos Pathogens. 6: e1001030. PMID 20686665 DOI: 10.1371/journal.ppat.1001030 |
0.194 |
|
1978 |
Postel E, Klein H, Levine AJ. The fidelity of phosphorylation of the adenovirus DNA-binding protein by an in vitro nuclear protein kinase from virus-infected cells. Virology. 86: 291-4. PMID 208253 DOI: 10.1016/0042-6822(78)90031-4 |
0.193 |
|
2007 |
Feng Z, Hu W, Teresky AK, Hernando E, Cordon-Cardo C, Levine AJ. Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations. Proceedings of the National Academy of Sciences of the United States of America. 104: 16633-8. PMID 17921246 DOI: 10.1073/pnas.0708043104 |
0.193 |
|
1973 |
Mayer A, Levine AJ. DNA replication in SV40-infected cells. 8. The distribution of replicating molecules at different stages of replication in SV40-infected cells. Virology. 50: 328-38. PMID 4344189 DOI: 10.1016/0042-6822(72)90384-4 |
0.193 |
|
1973 |
Ritzi EM, Levine AJ. The fragmentation of cellular DNA and the formation of pseudovirions during SV 40 infection of African green monkey kidney cells. The Journal of General Virology. 20: 353-67. PMID 4355330 DOI: 10.1099/0022-1317-20-3-353 |
0.192 |
|
1996 |
Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain Science. 274: 948-953. PMID 8875929 DOI: 10.1126/Science.274.5289.948 |
0.192 |
|
2021 |
Chan CS, Sun Y, Ke H, Zhao Y, Belete M, Zhang C, Feng Z, Levine AJ, Hu W. Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models. Life Science Alliance. 4. PMID 33376133 DOI: 10.26508/lsa.202000952 |
0.191 |
|
1993 |
Riou G, Lê MG, Travagli JP, Levine AJ, Moll UM. Poor prognosis of p53 gene mutation and nuclear overexpression of p53 protein in inflammatory breast carcinoma. Journal of the National Cancer Institute. 85: 1765-7. PMID 8411261 DOI: 10.1093/jnci/85.21.1765 |
0.191 |
|
2007 |
Bond GL, Levine AJ. A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans. Oncogene. 26: 1317-23. PMID 17322917 DOI: 10.1038/sj.onc.1210199 |
0.191 |
|
1991 |
Baim SB, Labow MA, Levine AJ, Shenk T. A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl β-D-thiogalactopyranoside Proceedings of the National Academy of Sciences of the United States of America. 88: 5072-5076. PMID 2052587 DOI: 10.1073/pnas.88.12.5072 |
0.19 |
|
1980 |
Ariga H, Klein H, Levine AJ, Horwitz MS. A cleavage product of the adenovirus DNA binding protein is active in DNA replication in vitro. Virology. 101: 307-10. PMID 6243830 DOI: 10.1016/0042-6822(80)90510-3 |
0.189 |
|
1979 |
Seidman MM, Levine AJ, Weintraub H. The asymmetric segregation of parental nucleosomes during chrosome replication. Cell. 18: 439-49. PMID 227608 DOI: 10.1016/0092-8674(79)90063-1 |
0.189 |
|
0 |
Lu H, Lin J, Chen J, Levine AJ. The regulation of p53-mediated transcription and the roles of hTAFII31 and mdm-2. Harvey Lectures. 90: 81-93. PMID 8803320 |
0.189 |
|
2012 |
Feng Z, Liu L, Zhang C, Zheng T, Wang J, Lin M, Zhao Y, Wang X, Levine AJ, Hu W. Chronic restraint stress attenuates p53 function and promotes tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 7013-8. PMID 22509031 DOI: 10.1073/pnas.1203930109 |
0.189 |
|
2012 |
Kobayashi S, Yamada-Okabe H, Suzuki M, Natori O, Kato A, Matsubara K, Jau Chen Y, Yamazaki M, Funahashi S, Yoshida K, Hashimoto E, Watanabe Y, Mutoh H, Ashihara M, Kato C, ... ... Levine AJ, et al. LGR5-positive colon cancer stem cells interconvert with drug-resistant LGR5-negative cells and are capable of tumor reconstitution. Stem Cells (Dayton, Ohio). 30: 2631-44. PMID 23081779 DOI: 10.1002/stem.1257 |
0.188 |
|
2010 |
Vazquez A, Grochola LF, Bond EE, Levine AJ, Taubert H, Müller TH, Würl P, Bond GL. Chemosensitivity profiles identify polymorphisms in the p53 network genes 14-3-3tau and CD44 that affect sarcoma incidence and survival. Cancer Research. 70: 172-80. PMID 19996285 DOI: 10.1158/0008-5472.CAN-09-2218 |
0.187 |
|
2000 |
Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature. 408: 307-10. PMID 11099028 DOI: 10.1038/35042675 |
0.187 |
|
2001 |
Ziemer LT, Pennica D, Levine AJ. Identification of a mouse homolog of the human BTEB2 transcription factor as a beta-catenin-independent Wnt-1-responsive gene. Molecular and Cellular Biology. 21: 562-74. PMID 11134343 DOI: 10.1128/MCB.21.2.562-574.2001 |
0.186 |
|
1981 |
Maltzman W, Oren M, Levine AJ. The structural relationships between 54,000-molecular-weight cellular tumor antigens detected in viral- and nonviral-transformed cells Virology. 112: 145-156. PMID 6264678 DOI: 10.1016/0042-6822(81)90620-6 |
0.185 |
|
2005 |
Ma B, Pan Y, Gunasekaran K, Venkataraghavan RB, Levine AJ, Nussinov R. Comparison of the protein-protein interfaces in the p53-DNA crystal structures: towards elucidation of the biological interface. Proceedings of the National Academy of Sciences of the United States of America. 102: 3988-93. PMID 15738397 DOI: 10.1073/Pnas.0500215102 |
0.185 |
|
2022 |
Tran AP, Tralie CJ, Reyes J, Moosmüller C, Belkhatir Z, Kevrekidis IG, Levine AJ, Deasy JO, Tannenbaum AR. Long-term p21 and p53 dynamics regulate the frequency of mitosis events and cell cycle arrest following radiation damage. Cell Death and Differentiation. PMID 36182991 DOI: 10.1038/s41418-022-01069-x |
0.184 |
|
1989 |
Seiberg M, Aloni Y, Levine AJ. The adenovirus type 2 DNA-binding protein interacts with the major late promoter attenuated RNA. Journal of Virology. 63: 1134-41. PMID 2492608 DOI: 10.1128/jvi.63.3.1134-1141.1989 |
0.184 |
|
1996 |
Elenbaas B, Dobbelstein M, Roth J, Shenk T, Levine AJ. The MDM2 Oncoprotein Binds Specifically to RNA through its RING Finger Domain Molecular Medicine. 2: 439-451. DOI: 10.1007/Bf03401903 |
0.184 |
|
1981 |
Rabek JP, Zakian VA, Levine AJ. The SV40 a gene product suppresses the adenovirus H5ts125 defect in DNA replication Virology. 109: 290-302. PMID 6259812 DOI: 10.1016/0042-6822(81)90500-6 |
0.184 |
|
2015 |
Puzio-Kuter AM, Laddha SV, Castillo-Martin M, Sun Y, Cordon-Cardo C, Chan CS, Levine AJ. Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma. Cell Death and Differentiation. PMID 25822339 DOI: 10.1038/Cdd.2015.27 |
0.184 |
|
2009 |
Hu W, Feng Z, Levine AJ. The regulation of human reproduction by p53 and its pathway. Cell Cycle (Georgetown, Tex.). 8: 3621-2. PMID 19884797 |
0.184 |
|
2006 |
Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JSK, Smemo S, Hinrichs A, Tacey K, Kwok S, Catanese J, Sninsky J, White TJ, Hollingworth P, Harris SL, Levine A, et al. O2-02-07 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.117 |
0.183 |
|
2015 |
Amelio I, Inoue S, Markert EK, Levine AJ, Knight RA, Mak TW, Melino G. TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation. Proceedings of the National Academy of Sciences of the United States of America. 112: 226-31. PMID 25535359 DOI: 10.1073/pnas.1410609111 |
0.183 |
|
1996 |
Wilson JB, Bell JL, Levine AJ. Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice. The Embo Journal. 15: 3117-26. PMID 8670812 |
0.183 |
|
1997 |
Hayashi S, Rubinfelsd B, Souza B, Polakis P, Wieschaus E, Levine AJ. A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates β-catenin but its zygotic expression is not essential for the regulation of Armadillo Proceedings of the National Academy of Sciences of the United States of America. 94: 242-247. PMID 8990193 DOI: 10.1073/pnas.94.1.242 |
0.183 |
|
2010 |
Levine AJ, Puzio-Kuter AM. The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science (New York, N.Y.). 330: 1340-4. PMID 21127244 DOI: 10.1126/science.1193494 |
0.183 |
|
1997 |
Bullions LC, Notterman DA, Chung LS, Levine AJ. Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities. Molecular and Cellular Biology. 17: 4501-8. PMID 9234707 DOI: 10.1128/MCB.17.8.4501 |
0.183 |
|
1992 |
Levine AJ. The p53 tumour suppressor gene and product Cancer Surveys. 12: 59-79. PMID 1638548 |
0.182 |
|
1981 |
Logan J, Nicolas JC, Topp WC, Girard M, Shenk T, Levine AJ. Transformation by adenovirus early region 2A temperature-sensitive mutants and their revertants. Virology. 115: 419-22. PMID 7314451 DOI: 10.1016/0042-6822(81)90126-4 |
0.182 |
|
2012 |
Markert EK, Levine AJ, Vazquez A. Proliferation and tissue remodeling in cancer: the hallmarks revisited. Cell Death & Disease. 3: e397. PMID 23034332 DOI: 10.1038/cddis.2012.140 |
0.182 |
|
2006 |
Pan Y, Ma B, Levine AJ, Nussinov R. Comparison of the human and worm p53 structures suggests a way for enhancing stability. Biochemistry. 45: 3925-33. PMID 16548519 DOI: 10.1021/Bi052242N |
0.181 |
|
1995 |
Bayle JH, Elenbaas B, Levine AJ. The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity. Proceedings of the National Academy of Sciences of the United States of America. 92: 5729-33. PMID 7777576 DOI: 10.1073/PNAS.92.12.5729 |
0.181 |
|
1980 |
Ross SR, Levine AJ, Galos RS, Williams J, Shenk T. Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants. Virology. 103: 475-92. PMID 7385588 |
0.181 |
|
2008 |
Murphy E, VanÃcek J, Robins H, Shenk T, Levine AJ. Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency. Proceedings of the National Academy of Sciences of the United States of America. 105: 5453-8. PMID 18378902 DOI: 10.1073/Pnas.0711910105 |
0.18 |
|
1982 |
Sarnow P, Ho YS, Williams J, Levine AJ. Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell. 28: 387-94. PMID 6277513 DOI: 10.1016/0092-8674(82)90356-7 |
0.179 |
|
2012 |
Tippin BL, Levine AJ, Materi AM, Song WL, Keku TO, Goodman JE, Sansbury LB, Das S, Dai A, Kwong AM, Lin AM, Lin JM, Park JM, Patterson RE, Chlebowski RT, et al. Hematopoietic prostaglandin D synthase (HPGDS): a high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer. Prostaglandins & Other Lipid Mediators. 97: 22-8. PMID 21821144 DOI: 10.1016/J.Prostaglandins.2011.07.006 |
0.178 |
|
1994 |
Marechal V, Elenbaas B, Piette J, Nicolas JC, Levine AJ. The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes. Molecular and Cellular Biology. 14: 7414-20. PMID 7935455 DOI: 10.1128/mcb.14.11.7414-7420.1994 |
0.178 |
|
2023 |
de Andrade KC, Strande NT, Kim J, Haley JS, Hatton JN, Frone MN, Khincha PP, Thone GM, Mirshahi UL, Schneider C, Desai H, Dove JT, Smelser DT, BioBank PM, Center RG, ... Levine AJ, et al. Genome-First Approach of the Prevalence and Cancer Phenotypes of Pathogenic or Likely Pathogenic Germline TP53 Variants. Hgg Advances. 100242. PMID 37777824 DOI: 10.1016/j.xhgg.2023.100242 |
0.178 |
|
1991 |
Levine AJ. Virus vector-mediated gene transfer. Microbiological Sciences. 4: 245-50. PMID 3155277 |
0.177 |
|
2009 |
Kulkarni DA, Vazquez A, Haffty BG, Bandera EV, Hu W, Sun YY, Toppmeyer DL, Levine AJ, Hirshfield KM. A polymorphic variant in human MDM4 associates with accelerated age of onset of estrogen receptor negative breast cancer. Carcinogenesis. 30: 1910-5. PMID 19762336 DOI: 10.1093/Carcin/Bgp224 |
0.176 |
|
1989 |
Frey AB, Levine AJ. p53-plus-ras-transformed rat embryo fibroblasts express tumor-specific transplantation antigen activity which is shared by independently transformed cells. Journal of Virology. 63: 5440-4. PMID 2531235 DOI: 10.1128/JVI.63.12.5440-5444.1989 |
0.175 |
|
2018 |
Wolff RA, Wang-Gillam A, Alvarez H, Tiriac H, Engle D, Hou S, Groff AF, San Lucas A, Bernard V, Allenson K, Castillo J, Kim D, Mulu F, Huang J, Stephens B, ... ... Levine AJ, et al. Dynamic changes during the treatment of pancreatic cancer. Oncotarget. 9: 14764-14790. PMID 29599906 DOI: 10.18632/Oncotarget.24483 |
0.175 |
|
1977 |
Levinson AD, Postel EH, Levine AJ. In vivo and in vitro phosphorylation of the adenovirus type 5 single strand-specific DNA-binding protein. Virology. 79: 144-59. PMID 405795 DOI: 10.1016/0042-6822(77)90341-5 |
0.175 |
|
2005 |
Harris SL, Gil G, Hu W, Robins H, Bond E, Hirshfield K, Feng Z, Yu X, Teresky AK, Bond G, Levine AJ. Single-nucleotide polymorphisms in the p53 pathway. Cold Spring Harbor Symposia On Quantitative Biology. 70: 111-9. PMID 16869744 DOI: 10.1101/Sqb.2005.70.024 |
0.174 |
|
2019 |
Levine AJ, Jenkins NA, Copeland NG. The Roles of Initiating Truncal Mutations in Human Cancers: The Order of Mutations and Tumor Cell Type Matters. Cancer Cell. 35: 10-15. PMID 30645969 DOI: 10.1016/j.ccell.2018.11.009 |
0.174 |
|
2010 |
Harris CR, Normart R, Yang Q, Stevenson E, Haffty BG, Ganesan S, Cordon-Cardo C, Levine AJ, Tang LH. Association of nuclear localization of a long interspersed nuclear element-1 protein in breast tumors with poor prognostic outcomes. Genes & Cancer. 1: 115-24. PMID 20948976 DOI: 10.1177/1947601909360812 |
0.174 |
|
1971 |
Levine AJ. Induction of mitochondrial DNA synthesis in monkey cells infected by simian virus 40 and (or) treated with calf serum Proceedings of the National Academy of Sciences of the United States of America. 68: 717-720. PMID 4323784 DOI: 10.1073/pnas.68.4.717 |
0.174 |
|
1991 |
Lozano G, Levine AJ. Tissue-specific expression of p53 in transgenic mice is regulated by intron sequences. Molecular Carcinogenesis. 4: 3-9. PMID 1848986 DOI: 10.1002/Mc.2940040103 |
0.174 |
|
1982 |
Schutzbank T, Robinson R, Oren M, Levine AJ. SV40 large tumor antigen can regulate some cellular transcripts in a positive fashion Cell. 30: 481-490. PMID 6291771 DOI: 10.1016/0092-8674(82)90245-8 |
0.173 |
|
2001 |
Notterman DA, Alon U, Sierk AJ, Levine AJ. Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Research. 61: 3124-30. PMID 11306497 |
0.173 |
|
1986 |
Ostapchuk P, Diffley JF, Bruder JT, Stillman B, Levine AJ, Hearing P. Interaction of a nuclear factor with the polyomavirus enhancer region. Proceedings of the National Academy of Sciences of the United States of America. 83: 8550-4. PMID 3022296 DOI: 10.1073/Pnas.83.22.8550 |
0.173 |
|
1987 |
van Dyke TA, Finlay C, Miller D, Marks J, Lozano G, Levine AJ. Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice Journal of Virology. 61: 2029-2032. PMID 3033329 DOI: 10.1128/Jvi.61.6.2029-2032.1987 |
0.173 |
|
1987 |
Cobb GW, Anderson DR, Sweeney DJ, Williams TA, Brockett P, Levine A, Clarke GM, Cooke D, Devore J, Peck R, Freund JE, Smith RM, Goldman RN, Weinberg JS, Johnson R, et al. Introductory Textbooks: A Framework for Evaluation Journal of the American Statistical Association. 82: 321. DOI: 10.2307/2289170 |
0.173 |
|
1991 |
Montalvo EA, Shi Y, Shenk TE, Levine AJ. Negative regulation of the BZLF1 promoter of Epstein-Barr virus. Journal of Virology. 65: 3647-55. PMID 1645787 DOI: 10.1128/Jvi.65.7.3647-3655.1991 |
0.172 |
|
2008 |
Huang Y, Krasnitz M, Rabadan R, Witten DM, Song Y, Levine AJ, Ho DD, Robins H. A recoding method to improve the humoral immune response to an HIV DNA vaccine. Plos One. 3: e3214. PMID 18791646 DOI: 10.1371/Journal.Pone.0003214 |
0.172 |
|
2015 |
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 112: E3495-504. PMID 26100862 DOI: 10.1073/Pnas.1507105112 |
0.172 |
|
2018 |
Matson KJE, Sathyamurthy A, Johnson KR, Kelly MC, Kelley MW, Levine AJ. Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing. Journal of Visualized Experiments : Jove. PMID 30371670 DOI: 10.3791/58413 |
0.171 |
|
2007 |
Hu W, Feng Z, Teresky AK, Levine AJ. p53 regulates maternal reproduction through LIF. Nature. 450: 721-4. PMID 18046411 DOI: 10.1038/nature05993 |
0.171 |
|
2005 |
Harris SL, Gil G, Robins H, Hu W, Hirshfield K, Bond E, Bond G, Levine AJ. Detection of functional single-nucleotide polymorphisms that affect apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 16297-302. PMID 16260726 DOI: 10.1073/Pnas.0508390102 |
0.171 |
|
2004 |
Plotkin JB, Robins H, Levine AJ. Tissue-specific codon usage and the expression of human genes. Proceedings of the National Academy of Sciences of the United States of America. 101: 12588-91. PMID 15314228 DOI: 10.1073/Pnas.0404957101 |
0.17 |
|
2024 |
Boruah N, Hoyos D, Moses R, Hausler R, Desai H, Le AN, Good M, Kelly G, Raghavakaimal A, Tayeb M, Narasimhamurthy M, Doucette A, Gabriel P, Feldman MJ, Park J, ... ... Levine AJ, et al. Distinct genomic and immunologic tumor evolution in germline driven breast cancers. Biorxiv : the Preprint Server For Biology. PMID 38617260 DOI: 10.1101/2024.04.03.588009 |
0.169 |
|
1980 |
Axelrod HR, Levine AJ. Expression of SV40 tumor antigen in SV40 transformed teratocarcinoma-derived cell lines. Journal of Cellular Physiology. 104: 249-52. PMID 6251099 DOI: 10.1002/jcp.1041040215 |
0.169 |
|
2008 |
Marsh GA, Rabadán R, Levine AJ, Palese P. Highly conserved regions of influenza a virus polymerase gene segments are critical for efficient viral RNA packaging. Journal of Virology. 82: 2295-304. PMID 18094182 DOI: 10.1128/Jvi.02267-07 |
0.169 |
|
1976 |
Levine AJ, van der Vliet PC, Sussenbach JS. The replication of papovavirus and adenovirus DNA. Current Topics in Microbiology and Immunology. 73: 67-124. PMID 178481 DOI: 10.1007/978-3-642-66306-2_3 |
0.168 |
|
2021 |
Matejcic M, Shaban HA, Quintana MW, Schumacher FR, Edlund CK, Naghi LA, Pai RK, Haile RW, Levine AJ, Buchanan DD, Jenkins MA, Figueiredo JC, Rennert G, Gruber SB, Li L, et al. Rare variants in the DNA repair pathway and the risk of colorectal cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 33627384 DOI: 10.1158/1055-9965.EPI-20-1457 |
0.168 |
|
1984 |
Hearing JC, Nicolas JC, Levine AJ. Identification of Epstein-Barr virus sequences that encode a nuclear antigen expressed in latently infected lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 81: 4373-4377. PMID 6087322 |
0.167 |
|
1971 |
Fox TO, Levine AJ. Relationship between virus-induced cellular deoxyribonucleic acid synthesis and transformation by simian virus 40. Journal of Virology. 7: 473-7. PMID 4329563 DOI: 10.1128/jvi.7.4.473-477.1971 |
0.167 |
|
2007 |
Levine AJ, Hu W, Feng Z, Gil G. Reconstructing signal transduction pathways: challenges and opportunities. Annals of the New York Academy of Sciences. 1115: 32-50. PMID 17934060 DOI: 10.1196/annals.1407.018 |
0.166 |
|
1982 |
Sarnow P, Sullivan CA, Levine AJ. A monoclonal antibody detecting the adenovirus type 5-E1b-58Kd tumor antigen: characterization of the E1b-58Kd tumor antigen in adenovirus-infected and -transformed cells. Virology. 120: 510-7. PMID 7048730 DOI: 10.1016/0042-6822(82)90054-X |
0.166 |
|
1976 |
Rosenwirth B, Anderson C, Levine AJ. Tryptic fingerprint analysis of adenovirus types 2, 5 and 12 DNA-Binding proteins. Virology. 69: 617-25. PMID 1258364 DOI: 10.1016/0042-6822(76)90490-6 |
0.165 |
|
1989 |
Frey A, Chittenden T, Levine AJ. Epstein-Barr virus DNA replication. Current Topics in Microbiology and Immunology. 144: 227-32. PMID 2551584 DOI: 10.1007/978-3-642-74578-2_28 |
0.165 |
|
1975 |
Levine AJ. The replication of papovavirus DNA. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. Progres En Virologie Medicale. 17: 1-37. PMID 4371524 |
0.164 |
|
1983 |
Nicolas JC, Young CS, Suarez F, Girard M, Levine AJ. Detection, rescue, and mapping of mutations in the adenovirus DNA binding protein gene. Proceedings of the National Academy of Sciences of the United States of America. 80: 1674-7. PMID 6300867 DOI: 10.1073/PNAS.80.6.1674 |
0.164 |
|
1979 |
Linzer DI, Levine AJ. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell. 17: 43-52. PMID 222475 DOI: 10.1016/0092-8674(79)90293-9 |
0.163 |
|
2007 |
Atwal GS, Bond GL, Metsuyanim S, Papa M, Friedman E, Distelman-Menachem T, Ben Asher E, Lancet D, Ross DA, Sninsky J, White TJ, Levine AJ, Yarden R. Haplotype structure and selection of the MDM2 oncogene in humans. Proceedings of the National Academy of Sciences of the United States of America. 104: 4524-9. PMID 17360557 DOI: 10.1073/pnas.0610998104 |
0.163 |
|
1993 |
Levine AJ. The tumor suppressor genes. Annual Review of Biochemistry. 62: 623-51. PMID 8394683 DOI: 10.1146/annurev.bi.62.070193.003203 |
0.162 |
|
2007 |
Ma B, Pan Y, Zheng J, Levine AJ, Nussinov R. Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets. Nucleic Acids Research. 35: 2986-3001. PMID 17439973 DOI: 10.1093/Nar/Gkm192 |
0.162 |
|
1976 |
Levine AJ. SV40 and adenovirus early functions involved in DNA replication and transformation Bba - Reviews On Cancer. 458: 213-241. PMID 184845 DOI: 10.1016/0304-419X(76)90001-9 |
0.162 |
|
1975 |
Rosenwirth B, Shiroki K, Levine AJ, Shimojo H. Isolation and characterization of adenovirus type 12 DNA binding proteins. Virology. 67: 14-23. PMID 1162902 DOI: 10.1016/0042-6822(75)90399-2 |
0.162 |
|
2015 |
Sun L, Tan R, Xu J, LaFace J, Gao Y, Xiao Y, Attar M, Neumann C, Li GM, Su B, Liu Y, Nakajima S, Levine AS, Lan L. Targeted DNA damage at individual telomeres disrupts their integrity and triggers cell death. Nucleic Acids Research. 43: 6334-47. PMID 26082495 DOI: 10.1093/Nar/Gkv598 |
0.161 |
|
2009 |
Belyi VA, Levine AJ. One billion years of p53/p63/p73 evolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 17609-10. PMID 19826090 DOI: 10.1073/pnas.0910634106 |
0.161 |
|
1983 |
Schutzbank T, Levine AJ. Cells transformed by a wide variety of agents express higher abundance levels of some cellular RNA species. Journal of Cellular Biochemistry. 19: 259-65. PMID 6185512 DOI: 10.1002/JCB.240190307 |
0.161 |
|
1989 |
Chittenden T, Lupton S, Levine AJ. Functional limits of oriP, the Epstein-Barr virus plasmid origin of replication. Journal of Virology. 63: 3016-3025. PMID 2542609 DOI: 10.1128/Jvi.63.7.3016-3025.1989 |
0.16 |
|
1993 |
Quartin RS, Levine AJ. A comparison of the properties of human p53 mutant alleles. Advances in Experimental Medicine and Biology. 330: 55-65. PMID 8368143 DOI: 10.1007/978-1-4615-2926-2_5 |
0.16 |
|
2010 |
Belyi VA, Levine AJ, Skalka AM. Sequences from ancestral single-stranded DNA viruses in vertebrate genomes: the parvoviridae and circoviridae are more than 40 to 50 million years old. Journal of Virology. 84: 12458-62. PMID 20861255 DOI: 10.1128/JVI.01789-10 |
0.159 |
|
2017 |
Sethna Z, Elhanati Y, Dudgeon CS, Callan CG, Levine AJ, Mora T, Walczak AM. Insights into immune system development and function from mouse T-cell repertoires. Proceedings of the National Academy of Sciences of the United States of America. PMID 28196891 DOI: 10.1073/Pnas.1700241114 |
0.159 |
|
2009 |
Tseng CY, Wang A, Zocchi G, Rolih B, Levine AJ. Elastic energy of protein-DNA chimeras. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 061912. PMID 20365195 DOI: 10.1103/Physreve.80.061912 |
0.158 |
|
2005 |
Pan Y, Ma B, Venkataraghavan RB, Levine AJ, Nussinov R. In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1. Biochemistry. 44: 1423-32. PMID 15683227 DOI: 10.1021/Bi047845Y |
0.158 |
|
2016 |
Camara PG, Rosenbloom DI, Emmett KJ, Levine AJ, Rabadan R. Topological Data Analysis Generates High-Resolution, Genome-wide Maps of Human Recombination. Cell Systems. PMID 27345159 DOI: 10.1016/J.Cels.2016.05.008 |
0.158 |
|
2023 |
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, ... ... Levine AJ, et al. DNA methylation networks underlying mammalian traits. Science (New York, N.Y.). 381: eabq5693. PMID 37561875 DOI: 10.1126/science.abq5693 |
0.157 |
|
1982 |
Sarnow P, Hearing P, Anderson CW, Reich N, Levine AJ. Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix. Journal of Molecular Biology. 162: 565-83. PMID 7166756 DOI: 10.1016/0022-2836(82)90389-8 |
0.157 |
|
2012 |
Levine AJ. The evolution of the p53 family of genes. Cell Cycle (Georgetown, Tex.). 11: 214-5. PMID 22214668 DOI: 10.4161/cc.11.2.18899 |
0.156 |
|
2010 |
Wallace K, Grau MV, Levine AJ, Shen L, Hamdan R, Chen X, Gui J, Haile RW, Barry EL, Ahnen D, McKeown-Eyssen G, Baron JA, Issa JP. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prevention Research (Philadelphia, Pa.). 3: 1552-64. PMID 21149331 DOI: 10.1158/1940-6207.Capr-10-0047 |
0.156 |
|
1976 |
Topp W, Hall JD, Marsden M, Teresky AK, Rifkin D, Levine AJ, Pollack R. In vitro differentiation of teratomas and the distribution of creatine phosphokinase and plasminogen activator in teratocarcinoma-derived cells. Cancer Research. 36: 4217-23. PMID 184930 |
0.156 |
|
1989 |
Seiberg M, Kessler M, Levine AJ, Aloni Y. Human RNA polymerase II can prematurely terminate transcription of the adenovirus type 2 late transcription unit at a precise site that resembles a prokaryotic termination signal. Virus Genes. 1: 97-116. PMID 3508341 DOI: 10.1007/BF00125689 |
0.156 |
|
2012 |
Tucci P, Agostini M, Grespi F, Markert EK, Terrinoni A, Vousden KH, Muller PA, Dötsch V, Kehrloesser S, Sayan BS, Giaccone G, Lowe SW, Takahashi N, Vandenabeele P, Knight RA, ... Levine AJ, et al. Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 15312-7. PMID 22949650 DOI: 10.1073/Pnas.1110977109 |
0.156 |
|
2019 |
Mathews JC, Nadeem S, Levine AJ, Pouryahya M, Deasy JO, Tannenbaum A. Robust and interpretable PAM50 reclassification exhibits survival advantage for myoepithelial and immune phenotypes. Npj Breast Cancer. 5: 30. PMID 31531391 DOI: 10.1038/s41523-019-0124-8 |
0.155 |
|
1999 |
Alon U, Barkai N, Notterman DA, Gish K, Ybarra S, Mack D, Levine AJ. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proceedings of the National Academy of Sciences of the United States of America. 96: 6745-50. PMID 10359783 DOI: 10.1073/Pnas.96.12.6745 |
0.154 |
|
2012 |
Win AK, Lindor NM, Young JP, Macrae FA, Young GP, Williamson E, Parry S, Goldblatt J, Lipton L, Winship I, Leggett B, Tucker KM, Giles GG, Buchanan DD, Clendenning M, ... ... Levine AJ, et al. Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome. Journal of the National Cancer Institute. 104: 1363-72. PMID 22933731 DOI: 10.1093/Jnci/Djs351 |
0.154 |
|
2020 |
Dobbelstein M, Levine AJ. Mdm2 - open questions. Cancer Science. PMID 32335977 DOI: 10.1111/cas.14433 |
0.153 |
|
2015 |
Zhang X, Schulz R, Edmunds S, Krüger E, Markert E, Gaedcke J, Cormet-Boyaka E, Ghadimi M, Beissbarth T, Levine AJ, Moll UM, Dobbelstein M. MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP. Molecular Cell. PMID 26145175 DOI: 10.1016/j.molcel.2015.05.036 |
0.153 |
|
2005 |
Bhanot G, Alexe G, Levine AJ, Stolovitzky G. Robust diagnosis of non-Hodgkin lymphoma phenotypes validated on gene expression data from different laboratories. Genome Informatics. International Conference On Genome Informatics. 16: 233-44. PMID 16362926 DOI: 10.11234/Gi1990.16.233 |
0.153 |
|
1999 |
Schell TD, Mylin LM, Georgoff I, Teresky AK, Levine AJ, Tevethia SS. Cytotoxic T-lymphocyte epitope immunodominance in the control of choroid plexus tumors in simian virus 40 large T antigen transgenic mice. Journal of Virology. 73: 5981-93. PMID 10364350 DOI: 10.1128/Jvi.73.7.5981-5993.1999 |
0.152 |
|
2020 |
Levine AJ. Non-Random Selection of Cancer-Causing Mutations in Tissue-Specific Stem Cells Cause Cancer. Journal of Clinical Oncology and Research. 8. PMID 33354623 |
0.152 |
|
1980 |
Klein H, Maltzman W, Levine AJ. Structure-function relationships of the adenovirus DNA-binding protein. The Journal of Biological Chemistry. 254: 11051-60. PMID 227858 |
0.152 |
|
2020 |
Skinnider MA, Squair JW, Kathe C, Anderson MA, Gautier M, Matson KJE, Milano M, Hutson TH, Barraud Q, Phillips AA, Foster LJ, La Manno G, Levine AJ, Courtine G. Cell type prioritization in single-cell data. Nature Biotechnology. PMID 32690972 DOI: 10.1038/S41587-020-0605-1 |
0.151 |
|
1990 |
Wilson JB, Weinberg W, Johnson R, Yuspa S, Levine AJ. Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6. Cell. 61: 1315-27. PMID 1694724 DOI: 10.1016/0092-8674(90)90695-B |
0.151 |
|
1995 |
Levine AJ, Wu MC, Chang A, Silver A, Attiyeh EF, Lin J, Epstein CB. The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype. Annals of the New York Academy of Sciences. 768: 111-28. PMID 8526340 DOI: 10.1111/j.1749-6632.1995.tb12115.x |
0.151 |
|
2005 |
Alexe G, Bhanot G, Venkataraghavan B, Ramaswamy R, Lepre J, Levine AJ, Stolovitzky G. A robust meta-classification strategy for cancer diagnosis from gene expression data. Proceedings / Ieee Computational Systems Bioinformatics Conference, Csb. Ieee Computational Systems Bioinformatics Conference. 322-5. PMID 16447989 DOI: 10.1109/CSB.2005.7 |
0.151 |
|
1976 |
Postel EH, Levine AJ. The requirement of simian virus 40 gene A product for the stimulation of cellular thymidine kinase activity after viral infection. Virology. 73: 206-15. PMID 183353 DOI: 10.1016/0042-6822(76)90075-1 |
0.151 |
|
1997 |
Broach JR, Levine AJ. Oncogenes and cell proliferation. Current Opinion in Genetics & Development. 7: 1-6. PMID 9024641 DOI: 10.1016/S0959-437X(97)80102-5 |
0.15 |
|
1995 |
Levine AJ, Broach JR. Oncogenes and cell proliferation. Current Opinion in Genetics & Development. 5: 1-4. PMID 7749316 DOI: 10.1016/S0959-437X(95)90045-4 |
0.15 |
|
2006 |
Levine AJ, Brivanlou AH. GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos. Development (Cambridge, England). 133: 209-16. PMID 16339188 DOI: 10.1242/dev.02192 |
0.15 |
|
2009 |
Puzio-Kuter AM, Levine AJ. Stem cell biology meets p53. Nature Biotechnology. 27: 914-5. PMID 19816447 DOI: 10.1038/nbt1009-914 |
0.15 |
|
2020 |
Mathews JC, Nadeem S, Pouryahya M, Belkhatir Z, Deasy JO, Levine AJ, Tannenbaum AR. Functional network analysis reveals an immune tolerance mechanism in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601217 DOI: 10.1073/Pnas.2002179117 |
0.15 |
|
1977 |
Topp W, Hall JD, Rifkin D, Levine AJ, Pollack R. The characterization of SV40-transformed cell lines derived from mouse teratocarcinoma: growth properties and differentiated characteristics. Journal of Cellular Physiology. 93: 269-76. PMID 201648 DOI: 10.1002/jcp.1040930212 |
0.149 |
|
1974 |
Sen A, Levine AJ. SV40 nucleoprotein complex activity unwinds superhelical turns in SV40 DNA. Nature. 249: 343-4. PMID 4366777 DOI: 10.1038/249343A0 |
0.149 |
|
2019 |
Wong C, Tang LH, Davidson C, Vosburgh E, Chen W, Foran DJ, Notterman DA, Levine AJ, Xu EY. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death and Differentiation. PMID 31160716 DOI: 10.1038/S41418-019-0355-0 |
0.149 |
|
2023 |
Lu AT, Fei Z, Haghani A, Robeck TR, Zoller JA, Li CZ, Lowe R, Yan Q, Zhang J, Vu H, Ablaeva J, Acosta-Rodriguez VA, Adams DM, Almunia J, Aloysius A, ... ... Levine AJ, et al. Universal DNA methylation age across mammalian tissues. Nature Aging. PMID 37563227 DOI: 10.1038/s43587-023-00462-6 |
0.149 |
|
2011 |
Vazquez A, Kulkarni D, Grochola LF, Bond GL, Barnard N, Toppmeyer D, Levine AJ, Hirshfield KM. A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence. International Journal of Cancer. Journal International Du Cancer. 128: 2335-43. PMID 20669227 DOI: 10.1002/ijc.25582 |
0.148 |
|
2012 |
Wong C, Vosburgh E, Levine AJ, Cong L, Xu EY. Human neuroendocrine tumor cell lines as a three-dimensional model for the study of human neuroendocrine tumor therapy. Journal of Visualized Experiments : Jove. e4218. PMID 22929519 DOI: 10.3791/4218 |
0.148 |
|
2015 |
Marbach-Bar N, Bahat A, Ashkenazi S, Golan-Mashiach M, Haimov O, Wu SY, Chiang CM, Puzio-Kuter A, Hirshfield KM, Levine AJ, Dikstein R. DTIE, a novel core promoter element that directs start site selection in TATA-less genes. Nucleic Acids Research. PMID 26464433 DOI: 10.1093/Nar/Gkv1032 |
0.148 |
|
1997 |
Dobbelstein M, Roth J, Kimberly WT, Levine AJ, Shenk T. Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. The Embo Journal. 16: 4276-84. PMID 9250671 DOI: 10.1093/Emboj/16.14.4276 |
0.148 |
|
2021 |
Squair JW, Gautier M, Kathe C, Anderson MA, James ND, Hutson TH, Hudelle R, Qaiser T, Matson KJE, Barraud Q, Levine AJ, La Manno G, Skinnider MA, Courtine G. Confronting false discoveries in single-cell differential expression. Nature Communications. 12: 5692. PMID 34584091 DOI: 10.1038/s41467-021-25960-2 |
0.147 |
|
1981 |
Oren M, Maltzman W, Levine AJ. Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells Molecular and Cellular Biology. 1: 101-110. PMID 6100960 DOI: 10.1128/mcb.1.2.101-110.1981 |
0.147 |
|
1997 |
Titenko-Holland N, Levine AJ, Smith MT, Quintana PJ, Boeniger M, Hayes R, Suruda A, Schulte P. Quantification of epithelial cell micronuclei by fluorescence in situ hybridization (FISH) in mortuary science students exposed to formaldehyde. Mutation Research. 371: 237-48. PMID 9008725 DOI: 10.1016/S0165-1218(96)90112-3 |
0.147 |
|
1997 |
Uesugi M, Nyanguile O, Lu H, Levine AJ, Verdine GL. Induced alpha helix in the VP16 activation domain upon binding to a human TAF. Science (New York, N.Y.). 277: 1310-3. PMID 9271577 DOI: 10.1126/Science.277.5330.1310 |
0.146 |
|
2006 |
Cully M, You H, Levine AJ, Mak TW. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nature Reviews. Cancer. 6: 184-92. PMID 16453012 DOI: 10.1038/nrc1819 |
0.145 |
|
2011 |
Mehta MS, Vazquez A, Kulkarni DA, Kerrigan JE, Atwal G, Metsugi S, Toppmeyer DL, Levine AJ, Hirshfield KM. Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes. Breast Cancer Research and Treatment. 125: 861-8. PMID 20658316 DOI: 10.1007/s10549-010-1062-1 |
0.145 |
|
2013 |
Peschiaroli A, Giacobbe A, Formosa A, Markert EK, Bongiorno-Borbone L, Levine AJ, Candi E, D'Alessandro A, Zolla L, Finazzi Agrò A, Melino G. miR-143 regulates hexokinase 2 expression in cancer cells. Oncogene. 32: 797-802. PMID 22469988 DOI: 10.1038/onc.2012.100 |
0.144 |
|
2015 |
Liu Z, Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN. Immune homeostasis enforced by co-localized effector and regulatory T cells. Nature. PMID 26605524 DOI: 10.1038/Nature16169 |
0.144 |
|
2021 |
Elkin R, Oh JH, Liu YL, Selenica P, Weigelt B, Reis-Filho JS, Zamarin D, Deasy JO, Norton L, Levine AJ, Tannenbaum AR. Geometric network analysis provides prognostic information in patients with high grade serous carcinoma of the ovary treated with immune checkpoint inhibitors. Npj Genomic Medicine. 6: 99. PMID 34819508 DOI: 10.1038/s41525-021-00259-9 |
0.144 |
|
2011 |
Markert EK, Mizuno H, Vazquez A, Levine AJ. Molecular classification of prostate cancer using curated expression signatures. Proceedings of the National Academy of Sciences of the United States of America. 108: 21276-81. PMID 22123976 DOI: 10.1073/pnas.1117029108 |
0.144 |
|
2010 |
Figueiredo JC, Levine AJ, Lee WH, Conti DV, Poynter JN, Campbell PT, Duggan D, Lewinger JP, Martinez ME, Ulrich CM, Newcomb P, Potter J, Limburg PJ, Hopper J, Jenkins MA, et al. Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes & Control : Ccc. 21: 597-608. PMID 20037791 DOI: 10.1007/S10552-009-9489-6 |
0.143 |
|
1997 |
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell. 88: 323-31. PMID 9039259 DOI: 10.1016/S0092-8674(00)81871-1 |
0.143 |
|
2021 |
Amelio I, Melino G, Levine AJ. Bispecific antibodies come to the aid of cancer immunotherapy. Molecular Oncology. PMID 33942515 DOI: 10.1002/1878-0261.12977 |
0.143 |
|
1980 |
Linzer DI, Maltzman W, Levine AJ. The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen. Virology. 98: 308-18. PMID 228475 DOI: 10.1016/0042-6822(79)90554-3 |
0.143 |
|
2012 |
Wagh K, Bhatia A, Alexe G, Reddy A, Ravikumar V, Seiler M, Boemo M, Yao M, Cronk L, Naqvi A, Ganesan S, Levine AJ, Bhanot G. Lactase persistence and lipid pathway selection in the Maasai. Plos One. 7: e44751. PMID 23028602 DOI: 10.1371/Journal.Pone.0044751 |
0.142 |
|
2001 |
Li L, Darden TA, Weinberg CR, Levine AJ, Pedersen LG. Gene assessment and sample classification for gene expression data using a genetic algorithm/k-nearest neighbor method. Combinatorial Chemistry & High Throughput Screening. 4: 727-39. PMID 11894805 DOI: 10.2174/1386207013330733 |
0.142 |
|
1981 |
Nicolas JC, Suarez F, Levine AJ, Girard M. Temperature-independent revertants of adenovirus H5ts125 and H5ts107 mutants in the DNA binding protein: isolation of a new class of host range temperature conditional revertants. Virology. 108: 521-4. PMID 6894045 DOI: 10.1016/0042-6822(81)90461-X |
0.142 |
|
1987 |
Van Dyke TA, Finlay C, Miller D, Marks J, Lozano G, Levine AJ. Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice. Journal of Virology. 61: 2029-2032. DOI: 10.1128/jvi.61.6.2029-2032.1987 |
0.142 |
|
2016 |
Contractor T, Kobayashi S, da Silva E, Clausen R, Chan C, Vosburgh E, Tang LH, Levine AJ, Harris CR. Sexual dimorphism of liver metastasis by murine pancreatic neuroendocrine tumors is affected by expression of complement C5. Oncotarget. PMID 27105526 DOI: 10.18632/oncotarget.8874 |
0.141 |
|
2008 |
Levine AJ, Vosburgh E. P53 mutations in lymphomas: position matters. Blood. 112: 2997-8. PMID 18840714 DOI: 10.1182/blood-2008-07-167718 |
0.141 |
|
2001 |
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, ... ... Levine AJ, et al. The sequence of the human genome. Science (New York, N.Y.). 291: 1304-51. PMID 11181995 DOI: 10.1126/Science.1058040 |
0.14 |
|
2006 |
Rabadan R, Levine AJ, Robins H. Comparison of avian and human influenza A viruses reveals a mutational bias on the viral genomes. Journal of Virology. 80: 11887-91. PMID 16987977 DOI: 10.1128/Jvi.01414-06 |
0.14 |
|
2012 |
Weisbart RH, Gera JF, Chan G, Hansen JE, Li E, Cloninger C, Levine AJ, Nishimura RN. A cell-penetrating bispecific antibody for therapeutic regulation of intracellular targets. Molecular Cancer Therapeutics. 11: 2169-73. PMID 22863609 DOI: 10.1158/1535-7163.MCT-12-0476-T |
0.14 |
|
1971 |
Anderson WR, Levine AJ, MacMillan D. Granulosa-theca cell tumors: clinical and pathologic study. American Journal of Obstetrics and Gynecology. 110: 32-5. PMID 5573606 DOI: 10.1016/0002-9378(71)90209-2 |
0.139 |
|
2006 |
Levine AJ, Feng Z, Mak TW, You H, Jin S. Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Genes & Development. 20: 267-75. PMID 16452501 DOI: 10.1101/gad.1363206 |
0.138 |
|
2007 |
Alexe G, Dalgin GS, Scanfeld D, Tamayo P, Mesirov JP, DeLisi C, Harris L, Barnard N, Martel M, Levine AJ, Ganesan S, Bhanot G. High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates. Cancer Research. 67: 10669-76. PMID 18006808 DOI: 10.1158/0008-5472.Can-07-0539 |
0.138 |
|
2008 |
Rabadan R, Levine AJ, Krasnitz M. Non-random reassortment in human influenza A viruses. Influenza and Other Respiratory Viruses. 2: 9-22. PMID 19453489 DOI: 10.1111/J.1750-2659.2007.00030.X |
0.137 |
|
1995 |
Decker DA, Morris LW, Levine AJ, Pettinga JE, Grudzien JL, Farkas DH. Immunohistochemical analysis of P-glycoprotein expression in breast cancer: clinical correlations. Annals of Clinical and Laboratory Science. 25: 52-9. PMID 7762969 |
0.136 |
|
2005 |
Haile RW, Yochim JM, Cortessis VK, Lin J, Levine AJ, Diep A, Danenberg K, Danenberg P. A molecular/epidemiologic analysis of expression of cyclooxygenases 1 and 2, use of nonsteroidal antiinflammatory drugs, and risk of colorectal adenoma. Clinical Colorectal Cancer. 4: 390-5. PMID 15807932 DOI: 10.3816/Ccc.2005.N.011 |
0.136 |
|
1993 |
Levine AJ, Burger MM. UICC Study Group on Basic and Clinical Cancer Research: genotypes and phenotypes of tumor suppressors. Meeting held at Woods Hole, MA, October 1-4, 1992. International Journal of Cancer. Journal International Du Cancer. 53: 883-5. PMID 8473046 DOI: 10.1002/ijc.2910530602 |
0.136 |
|
2010 |
Levine AJ, Figueiredo JC, Lee W, Conti DV, Kennedy K, Duggan DJ, Poynter JN, Campbell PT, Newcomb P, Martinez ME, Hopper JL, Le Marchand L, Baron JA, Limburg PJ, Ulrich CM, et al. A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 1812-21. PMID 20615890 DOI: 10.1158/1055-9965.Epi-10-0151 |
0.136 |
|
2010 |
Liu H, Brannon AR, Reddy AR, Alexe G, Seiler MW, Arreola A, Oza JH, Yao M, Juan D, Liou LS, Ganesan S, Levine AJ, Rathmell WK, Bhanot GV. Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma. Bmc Systems Biology. 4: 51. PMID 20420713 DOI: 10.1186/1752-0509-4-51 |
0.136 |
|
2016 |
Jenkins CL, Bagarazzi ML, Kiem HP, Levine AJ, Ando D, June CH, Reid T, Emery DW. Rethinking the Regulatory Infrastructure for Human Gene Transfer Clinical Trials. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 1173-7. PMID 27506378 DOI: 10.1038/Mt.2016.133 |
0.135 |
|
2000 |
Zhao R, Gish K, Murphy M, Yin Y, Notterman D, Hoffman WH, Tom E, Mack DH, Levine AJ. The transcriptional program following p53 activation. Cold Spring Harbor Symposia On Quantitative Biology. 65: 475-82. PMID 12760064 |
0.135 |
|
2008 |
Robins H, Krasnitz M, Levine AJ. The computational detection of functional nucleotide sequence motifs in the coding regions of organisms. Experimental Biology and Medicine (Maywood, N.J.). 233: 665-73. PMID 18408149 DOI: 10.3181/0704-Mr-97 |
0.134 |
|
1984 |
Nowak B, Sullivan C, Sarnow P, Thomas R, Bricout F, Nicolas JC, Fleckenstein B, Levine AJ. Characterization of monoclonal antibodies and polyclonal immune sera directed against human cytomegalovirus virion proteins. Virology. 132: 325-38. PMID 6322416 DOI: 10.1016/0042-6822(84)90039-4 |
0.134 |
|
2011 |
Nicolau M, Levine AJ, Carlsson G. Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival. Proceedings of the National Academy of Sciences of the United States of America. 108: 7265-70. PMID 21482760 DOI: 10.1073/Pnas.1102826108 |
0.133 |
|
1976 |
Shiroki K, Shimojo H, Levine AJ, Sekikawa K, Rabek J. Suppression of the temperature-sensitive character of adenovirus 12 early mutants in monkey cells transformed by an adenovirus 7-simian virus 40 hybrid. Virology. 69: 431-7. PMID 176780 DOI: 10.1016/0042-6822(76)90474-8 |
0.133 |
|
1987 |
Yagaloff KA, Lozano G, van Dyke T, Levine AJ, Hartig PR. Serotonin 5-HT1C receptors are expressed at high density on choroid plexus tumors from transgenic mice. Brain Research. 385: 389-94. PMID 3022874 DOI: 10.1016/0006-8993(86)91089-9 |
0.133 |
|
1975 |
Postel EH, Levine AJ. Studies on the regulation of deoxypyrimidine kinases in normal, SV40-transformed and SV40- and adenovirus-infected mouse cells in culture. Virology. 63: 404-20. PMID 163528 DOI: 10.1016/0042-6822(75)90313-X |
0.133 |
|
2012 |
Evans AA, Levine AJ. High-energy deformation of filaments with internal structure and localized torque-induced melting of DNA. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 85: 051915. PMID 23004795 DOI: 10.1103/Physreve.85.051915 |
0.132 |
|
1999 |
Muller AJ, Heiden KB, Teresky AK, Levine AJ. Genetic mapping of the embryonal carcinoma transplantation resistance locus Gt(B6) to mouse Chromosome 8. Immunogenetics. 49: 949-56. PMID 10501837 DOI: 10.1007/S002510050578 |
0.132 |
|
1984 |
Sarnow P, Hearing P, Anderson CW, Halbert DN, Shenk T, Levine AJ. Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. Journal of Virology. 49: 692-700. PMID 6699935 DOI: 10.1128/Jvi.49.3.692-700.1984 |
0.132 |
|
1983 |
Levine AJ. The nature of the host range restriction of SV40 and polyoma viruses in embryonal carcinoma cells. Current Topics in Microbiology and Immunology. 101: 1-30. PMID 6303700 DOI: 10.1007/978-3-642-68654-2_1 |
0.132 |
|
2013 |
Levine AJ, Horvath S, Miller EN, Singer EJ, Shapshak P, Baldwin GC, MartÃnez-Maza O, Witt MD, Langfelder P. Transcriptome analysis of HIV-infected peripheral blood monocytes: gene transcripts and networks associated with neurocognitive functioning. Journal of Neuroimmunology. 265: 96-105. PMID 24094461 DOI: 10.1016/J.Jneuroim.2013.09.016 |
0.132 |
|
2008 |
Shapshak P, Chiappelli F, Commins D, Singer E, Levine AJ, Somboonwit C, Minagar A, Pellionisz AJ. Molecular epigenetics, chromatin, and NeuroAIDS/HIV: translational implications. Bioinformation. 3: 53-7. PMID 19052667 DOI: 10.6026/97320630003053 |
0.132 |
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1983 |
Reich NC, Sarnow P, Duprey E, Levine AJ. Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein. Virology. 128: 480-4. PMID 6310869 DOI: 10.1016/0042-6822(83)90274-X |
0.132 |
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2014 |
Hait WN, Levine AJ. Genomic complexity: a call to action. Science Translational Medicine. 6: 255cm10. PMID 25253671 DOI: 10.1126/scitranslmed.3009148 |
0.132 |
|
2005 |
Robins H, Krasnitz M, Barak H, Levine AJ. A relative-entropy algorithm for genomic fingerprinting captures host-phage similarities. Journal of Bacteriology. 187: 8370-4. PMID 16321941 DOI: 10.1128/Jb.187.24.8370-8374.2005 |
0.131 |
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2016 |
Cámara PG, Levine AJ, Rabadán R. Inference of Ancestral Recombination Graphs through Topological Data Analysis. Plos Computational Biology. 12: e1005071. PMID 27532298 DOI: 10.1371/Journal.Pcbi.1005071 |
0.131 |
|
2010 |
Levine AJ, Figueiredo JC, Lee W, Poynter JN, Conti D, Duggan DJ, Campbell PT, Newcomb P, Martinez ME, Hopper JL, Le Marchand L, Baron JA, Limburg PJ, Ulrich CM, Haile RW. Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 89-100. PMID 20056627 DOI: 10.1158/1055-9965.Epi-09-0727 |
0.131 |
|
1981 |
Nicolas JC, Levine AJ. Multiplicity-dependent host range restriction of human adenovirus in human embryonal carcinoma cells. Virology. 113: 787-9. PMID 7269261 DOI: 10.1016/0042-6822(81)90209-9 |
0.13 |
|
1986 |
Pennica D, Goeddel DV, Hayflick JS, Reich NC, Anderson CW, Levine AJ. The amino acid sequence of murine p53 determined from a c-DNA clone. Virology. 134: 477-82. PMID 6400059 DOI: 10.1016/0042-6822(84)90316-7 |
0.13 |
|
1997 |
Freedman DA, Epstein CB, Roth JC, Levine AJ. A Genetic Approach to Mapping the p53 Binding Site in the MDM2 Protein Molecular Medicine. 3: 248-259. DOI: 10.1007/BF03401678 |
0.129 |
|
1981 |
Oren M, Levine AJ. Immunoselection of simian virus 40 large T antigen messenger RNAs from transformed cells Virology. 113: 790-793. PMID 6267809 DOI: 10.1016/0042-6822(81)90210-5 |
0.129 |
|
1989 |
FREY AB, LEVINE AJ. Rat Embryo Fibroblasts Transformed by p53 Plus ras Possess Tumor-specific Transplantation Activity Annals of the New York Academy of Sciences. 567: 295-298. DOI: 10.1111/J.1749-6632.1989.Tb16485.X |
0.128 |
|
2017 |
Aronica L, Levine AJ, Brennan K, Mi J, Gardner C, Haile RW, Hitchins MP. A systematic review of studies of DNA methylation in the context of a weight loss intervention. Epigenomics. 9: 769-787. PMID 28517981 DOI: 10.2217/epi-2016-0182 |
0.128 |
|
2009 |
Figueiredo JC, Grau MV, Wallace K, Levine AJ, Shen L, Hamdan R, Chen X, Bresalier RS, McKeown-Eyssen G, Haile RW, Baron JA, Issa JP. Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1041-9. PMID 19336559 DOI: 10.1158/1055-9965.Epi-08-0926 |
0.128 |
|
2016 |
Chau R, Dashti SG, Ait Ouakrim D, Buchanan DD, Clendenning M, Rosty C, Winship IM, Young JP, Giles GG, Macrae FA, Boussioutas A, Parry S, Figueiredo JC, Levine AJ, Ahnen DJ, et al. Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome. International Journal of Epidemiology. PMID 27063605 DOI: 10.1093/Ije/Dyw036 |
0.128 |
|
1981 |
Linzer DI, Maltzman W, Levine AJ. Characterization of a murine cellular SV40 T antigen in SV40-transformed cells and uninfected embryonal carcinoma cells. Cold Spring Harbor Symposia On Quantitative Biology. 215-24. PMID 6253135 DOI: 10.1101/SQB.1980.044.01.025 |
0.128 |
|
2023 |
Gao C, Gohel CA, Leng Y, Ma J, Goldman D, Levine AJ, Penzo MA. Molecular and spatial profiling of the paraventricular nucleus of the thalamus. Elife. 12. PMID 36867023 DOI: 10.7554/eLife.81818 |
0.127 |
|
2012 |
Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, et al. The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. Plos One. 7: e46178. PMID 23049970 DOI: 10.1371/Journal.Pone.0046178 |
0.127 |
|
1977 |
Levinson AD, Levine AJ. The group C adenovirus tumor antigens: identification in infected and transformed cells and a peptide map analysis. Cell. 11: 871-9. PMID 408015 DOI: 10.1016/0092-8674(77)90298-7 |
0.127 |
|
1980 |
Maltzman W, Linzer DI, Brown F, Teresky AK, Rosenstraus M, Levine AJ. Permanent teratocarcinoma-derived cell lines stabilized by transformation with SV40 and SV40tsA mutant viruses. International Review of Cytology. Supplement. 173-89. PMID 230162 DOI: 10.1016/S0074-7696(08)60620-8 |
0.125 |
|
2021 |
Russ DE, Cross RBP, Li L, Koch SC, Matson KJE, Yadav A, Alkaslasi MR, Lee DI, Le Pichon CE, Menon V, Levine AJ. A harmonized atlas of mouse spinal cord cell types and their spatial organization. Nature Communications. 12: 5722. PMID 34588430 DOI: 10.1038/s41467-021-25125-1 |
0.125 |
|
2013 |
Levine AJ, Miller JA, Shapshak P, Gelman B, Singer EJ, Hinkin CH, Commins D, Morgello S, Grant I, Horvath S. Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease. Bmc Medical Genomics. 6: 4. PMID 23406646 DOI: 10.1186/1755-8794-6-4 |
0.124 |
|
2013 |
Corral R, Lewinger JP, Joshi AD, Levine AJ, Vandenberg DJ, Haile RW, Stern MC. Genetic variation in the base excision repair pathway, environmental risk factors, and colorectal adenoma risk. Plos One. 8: e71211. PMID 23951112 DOI: 10.1371/Journal.Pone.0071211 |
0.124 |
|
2014 |
Levine AJ, Panos SE, Horvath S. Genetic, transcriptomic, and epigenetic studies of HIV-associated neurocognitive disorder. Journal of Acquired Immune Deficiency Syndromes (1999). 65: 481-503. PMID 24583618 DOI: 10.1097/QAI.0000000000000069 |
0.123 |
|
1989 |
Marks JR, Lin J, Hinds P, Miller D, Levine AJ. Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen. Journal of Virology. 63: 790-797. DOI: 10.1128/jvi.63.2.790-797.1989 |
0.121 |
|
2010 |
Markert EK, Baas N, Levine AJ, Vazquez A. Higher order Boolean networks as models of cell state dynamics. Journal of Theoretical Biology. 264: 945-51. PMID 20303985 DOI: 10.1016/j.jtbi.2010.03.015 |
0.12 |
|
2019 |
Levine AJ. The many faces of p53: something for everyone. Journal of Molecular Cell Biology. PMID 30925588 DOI: 10.1093/jmcb/mjz026 |
0.12 |
|
2024 |
Levine AJ. Improving T cell killing and understanding senescence: Possible roles for in cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 121: e2402533121. PMID 38466858 DOI: 10.1073/pnas.2402533121 |
0.12 |
|
1999 |
Freedman DA, Levine AJ. Regulation of the p53 protein by the MDM2 oncoprotein--thirty-eighth G.H.A. Clowes Memorial Award Lecture. Cancer Research. 59: 1-7. PMID 9892174 |
0.12 |
|
1974 |
Melnick JL, Allison AC, Butel JS, Eckhart W, Eddy BE, Kit S, Levine AJ, Miles JA, Pagano JS, Sachs L, Vonka V. Papovaviridae. Intervirology. 3: 106-20. PMID 4373407 DOI: 10.1159/000149746 |
0.12 |
|
2012 |
Levine AJ, Service S, Miller EN, Reynolds SM, Singer EJ, Shapshak P, Martin EM, Sacktor N, Becker JT, Jacobson LP, Thompson P, Freimer N. Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 669-83. PMID 22628157 DOI: 10.1002/Ajmg.B.32071 |
0.119 |
|
2023 |
Lu AT, Fei Z, Haghani A, Robeck TR, Zoller JA, Li CZ, Lowe R, Yan Q, Zhang J, Vu H, Ablaeva J, Acosta-Rodriguez VA, Adams DM, Almunia J, Aloysius A, ... ... Levine AJ, et al. Author Correction: Universal DNA methylation age across mammalian tissues. Nature Aging. PMID 37674040 DOI: 10.1038/s43587-023-00499-7 |
0.118 |
|
1991 |
Sears AE, Hukkanen V, Labow MA, Levine AJ, Roizman B. Expression of the herpes simplex virus 1 alpha transinducing factor (VP16) does not induce reactivation of latent virus or prevent the establishment of latency in mice. Journal of Virology. 65: 2929-35. PMID 1851865 DOI: 10.1128/Jvi.65.6.2929-2935.1991 |
0.118 |
|
2000 |
Muller AJ, Teresky AK, Levine AJ. A male germ cell tumor-susceptibility-determining locus, pgct1, identified on murine chromosome 13. Proceedings of the National Academy of Sciences of the United States of America. 97: 8421-6. PMID 10890890 DOI: 10.1073/Pnas.140208197 |
0.118 |
|
2015 |
Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ. Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV. Journal of Neurovirology. PMID 26637429 DOI: 10.1007/S13365-015-0410-7 |
0.117 |
|
1998 |
Bullions LC, Levine AJ. The role of beta-catenin in cell adhesion, signal transduction, and cancer. Current Opinion in Oncology. 10: 81-7. PMID 9466489 DOI: 10.1097/00001622-199801000-00013 |
0.117 |
|
1983 |
Levine AJ. Transformation-associated tumor antigens. Advances in Cancer Research. 37: 75-109. PMID 6190362 DOI: 10.1016/S0065-230X(08)60882-9 |
0.117 |
|
2011 |
Levine AJ, Lee W, Figueiredo JC, Conti DV, Vandenberg DJ, Davis BD, Edlund CK, Henning SM, Heber D, Stern MC, Haile RW. Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study. Cancer Causes & Control : Ccc. 22: 541-52. PMID 21274745 DOI: 10.1007/S10552-011-9726-7 |
0.117 |
|
1996 |
Wilson JB, Bell JL, Levine AJ. Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice. The Embo Journal. 15: 3117-3126. DOI: 10.1002/j.1460-2075.1996.tb00674.x |
0.116 |
|
2016 |
Blanden AR, Yu X, Loh SN, Levine AJ, Carpizo DR. Corrigendum to "Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer" [Drug Discov. Today 20 (11) (2015) 1391-1397]. Drug Discovery Today. PMID 27477875 DOI: 10.1016/J.Drudis.2016.07.012 |
0.115 |
|
2008 |
Krasnitz M, Levine AJ, Rabadan R. Anomalies in the influenza virus genome database: new biology or laboratory errors? Journal of Virology. 82: 8947-50. PMID 18579605 DOI: 10.1128/Jvi.00101-08 |
0.114 |
|
2011 |
Levine AJ. Introduction: The Changing Directions of p53 Research. Genes & Cancer. 2: 382-4. PMID 21785490 DOI: 10.1177/1947601911413463 |
0.114 |
|
1976 |
Levine AJ. Summation: Molecular Mechanisms of Gene Regulation-Session Cancer Research. 36: 4295-4296. PMID 184934 |
0.114 |
|
1980 |
Balint RF, Linzer DI, Khoury G, Levine AJ. The expression of SV40 large T-antigen in embryonal carcinoma--SV40 transformed somatic cell hybrids. Virology. 100: 492-4. PMID 6243439 DOI: 10.1016/0042-6822(80)90540-1 |
0.113 |
|
2001 |
Jin S, Levine AJ. The p53 functional circuit. Journal of Cell Science. 114: 4139-40. PMID 11739646 |
0.113 |
|
1989 |
Cho HJ, Seiberg M, Georgoff I, Teresky AK, Marks JR, Levine AJ. Impact of the genetic background of transgenic mice upon the formation and timing of choroid plexus papillomas Journal of Neuroscience Research. 24: 115-122. PMID 2478718 DOI: 10.1002/Jnr.490240116 |
0.112 |
|
2005 |
James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development (Cambridge, England). 132: 1273-82. PMID 15703277 DOI: 10.1242/dev.01706 |
0.111 |
|
2020 |
Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders. Journal of Neurovirology. PMID 32394397 DOI: 10.1007/S13365-020-00846-Z |
0.111 |
|
1981 |
Rosenstraus MJ, Balint RF, Levine AJ. Pluripotency of somatic cell hybrids between nullipotent and pluripotent embryonal carcinoma cells. Somatic Cell Genetics. 6: 555-65. PMID 7444716 DOI: 10.1007/BF01539156 |
0.11 |
|
2012 |
Haile RW, John EM, Levine AJ, Cortessis VK, Unger JB, Gonzales M, Ziv E, Thompson P, Spruijt-Metz D, Tucker KL, Bernstein JL, Rohan TE, Ho GY, Bondy ML, Martinez ME, et al. A review of cancer in U.S. Hispanic populations. Cancer Prevention Research (Philadelphia, Pa.). 5: 150-63. PMID 22307564 DOI: 10.1158/1940-6207.Capr-11-0447 |
0.108 |
|
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