Zhenyu Yue - Publications

Affiliations: 
Neurosciences Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Neuroscience Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Pan PY, Zhu Y, Shen Y, Yue Z. Crosstalk between presynaptic trafficking and autophagy in Parkinson's disease. Neurobiology of Disease. PMID 29723605 DOI: 10.1016/j.nbd.2018.04.020  0.92
2017 Pan PY, Li X, Wang J, Powell J, Wang Q, Zhang Y, Chen Z, Wicinski B, Hof P, Ryan TA, Yue Z. Parkinson's disease associated LRRK2 hyperactive kinase mutant disrupts synaptic vesicle trafficking in ventral midbrain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29054882 DOI: 10.1523/JNEUROSCI.0964-17.2017  0.92
2016 Volpicelli-Daley LA, Abdelmotilib H, Liu Z, Stoyka L, Daher JP, Milnerwood AJ, Unni VK, Hirst WD, Yue Z, Zhao HT, Fraser K, Kennedy RE, West AB. G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7415-27. PMID 27413152 DOI: 10.1523/JNEUROSCI.3642-15.2016  0.92
2016 Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye LE, Liao J, Rosenfeld J, Yachelevich N, Chu ML, Mitchell WG, Boles RG, Moran E, Tokita M, Gorman E, ... ... Yue Z, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. Plos Genetics. 12: e1005848. PMID 27120463 DOI: 10.1371/journal.pgen.1005848  0.92
2015 Sweet ES, Saunier-Rebori B, Yue Z, Blitzer RD. The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11190-5. PMID 26269629 DOI: 10.1523/JNEUROSCI.0040-15.2015  0.92
2015 Lim J, Yue Z. Neuronal aggregates: formation, clearance, and spreading. Developmental Cell. 32: 491-501. PMID 25710535 DOI: 10.1016/j.devcel.2015.02.002  0.92
2014 McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. Plos Genetics. 10: e1004626. PMID 25275521 DOI: 10.1371/journal.pgen.1004626  0.92
2014 Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, et al. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron. 83: 1131-43. PMID 25155956 DOI: 10.1016/j.neuron.2014.07.040  0.92
2014 Yamamoto A, Yue Z. Autophagy and its normal and pathogenic states in the brain. Annual Review of Neuroscience. 37: 55-78. PMID 24821313 DOI: 10.1146/annurev-neuro-071013-014149  0.92
2014 Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, ... Yue Z, et al. A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity. Human Molecular Genetics. 23: 4887-905. PMID 24794857 DOI: 10.1093/hmg/ddu202  0.92
2014 Friedman AK, Walsh JJ, Juarez B, Ku SM, Chaudhury D, Wang J, Li X, Dietz DM, Pan N, Vialou VF, Neve RL, Yue Z, Han MH. Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Science (New York, N.Y.). 344: 313-9. PMID 24744379 DOI: 10.1126/science.1249240  0.92
2014 Pan PY, Yue Z. Genetic causes of Parkinson's disease and their links to autophagy regulation Parkinsonism and Related Disorders. 20. PMID 24262170 DOI: 10.1016/S1353-8020(13)70037-3  0.92
2013 Reed M, Morris SH, Jang S, Mukherjee S, Yue Z, Lukacs NW. Autophagy-inducing protein beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 2526-37. PMID 23894198 DOI: 10.4049/jimmunol.1300477  0.92
2013 Krebs CE, Karkheiran S, Powell JC, Cao M, Makarov V, Darvish H, Di Paolo G, Walker RH, Shahidi GA, Buxbaum JD, De Camilli P, Yue Z, Paisán-Ruiz C. The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures. Human Mutation. 34: 1200-7. PMID 23804563 DOI: 10.1002/humu.22372  0.92
2013 Sepulveda B, Mesias R, Li X, Yue Z, Benson DL. Short- and long-term effects of LRRK2 on axon and dendrite growth. Plos One. 8: e61986. PMID 23646112 DOI: 10.1371/journal.pone.0061986  0.92
2013 Yue Z, Yang XW. Dangerous duet: LRRK2 and α-synuclein jam at CMA. Nature Neuroscience. 16: 375-7. PMID 23528933 DOI: 10.1038/nn.3361  0.92
2013 Bezard E, Yue Z, Kirik D, Spillantini MG. Animal models of Parkinson's disease: limits and relevance to neuroprotection studies. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 61-70. PMID 22753348 DOI: 10.1002/mds.25108  0.92
2012 Sheng Z, Zhang S, Bustos D, Kleinheinz T, Le Pichon CE, Dominguez SL, Solanoy HO, Drummond J, Zhang X, Ding X, Cai F, Song Q, Li X, Yue Z, van der Brug MP, et al. Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations. Science Translational Medicine. 4: 164ra161. PMID 23241745 DOI: 10.1126/scitranslmed.3004485  0.92
2012 McMahon J, Huang X, Yang J, Komatsu M, Yue Z, Qian J, Zhu X, Huang Y. Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15704-14. PMID 23136410 DOI: 10.1523/JNEUROSCI.2392-12.2012  0.92
2012 Lachenmayer ML, Yue Z. Genetic animal models for evaluating the role of autophagy in etiopathogenesis of Parkinson disease Autophagy. 8: 1837-1838. PMID 22931754 DOI: 10.4161/auto.21859  0.92
2012 Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, et al. Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast. Journal of Alzheimer's Disease : Jad. 32: 949-67. PMID 22903131 DOI: 10.3233/JAD-2012-120178  0.92
2012 Friedman LG, Lachenmayer ML, Wang J, He L, Poulose SM, Komatsu M, Holstein GR, Yue Z. Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7585-93. PMID 22649237 DOI: 10.1523/JNEUROSCI.5809-11.2012  0.92
2012 Grundmann K, Glöckle N, Martella G, Sciamanna G, Hauser TK, Yu L, Castaneda S, Pichler B, Fehrenbacher B, Schaller M, Nuscher B, Haass C, Hettich J, Yue Z, Nguyen HP, et al. Generation of a novel rodent model for DYT1 dystonia. Neurobiology of Disease. 47: 61-74. PMID 22472189 DOI: 10.1016/j.nbd.2012.03.024  0.92
2012 Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU. Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation. Cell Host & Microbe. 11: 264-76. PMID 22423966 DOI: 10.1016/j.chom.2012.01.018  0.92
2012 Yue Z. Genetic mouse models for understanding LRRK2 biology, pathology and pre-clinical application Parkinsonism and Related Disorders. 18. PMID 22166428  0.92
2011 Yu Z, Wang AM, Adachi H, Katsuno M, Sobue G, Yue Z, Robins DM, Lieberman AP. Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice. Plos Genetics. 7: e1002321. PMID 22022281 DOI: 10.1371/journal.pgen.1002321  0.92
2011 Morris S, Swanson MS, Lieberman A, Reed M, Yue Z, Lindell DM, Lukacs NW. Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses Journal of Immunology. 187: 3953-3961. PMID 21911604 DOI: 10.4049/jimmunol.1100524  0.92
2011 Yue Z, Lachenmayer ML. Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications Movement Disorders. 26: 1386-1397. PMID 21538530 DOI: 10.1002/mds.23737  0.92
2011 Ishii Y, Papa L, Bahadur U, Yue Z, Aguirre-Ghiso J, Shioda T, Waxman S, Germain D. Bortezomib enhances the efficacy of fulvestrant by amplifying the aggregation of the estrogen receptor, which leads to a proapoptotic unfolded protein response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2292-300. PMID 21292820 DOI: 10.1158/1078-0432.CCR-10-1745  0.92
2011 Arsov I, Adebayo A, Kucerova-Levisohn M, Haye J, MacNeil M, Papavasiliou FN, Yue Z, Ortiz BD. A role for autophagic protein beclin 1 early in lymphocyte development. Journal of Immunology (Baltimore, Md. : 1950). 186: 2201-9. PMID 21239722 DOI: 10.4049/jimmunol.1002223  0.92
2010 Yue Z, Zhong Y. From a global view to focused examination: Understanding cellular function of lipid kinase VPS34-Beclin 1 complex in autophagy Journal of Molecular Cell Biology. 2: 305-307. PMID 20846953 DOI: 10.1093/jmcb/mjq028  0.92
2010 Liu M, Poulose S, Schuman E, Zaitsev AD, Dobson B, Auerbach K, Seyb K, Cuny GD, Glicksman MA, Stein RL, Yue Z. Development of a mechanism-based high-throughput screen assay for leucine-rich repeat kinase 2--discovery of LRRK2 inhibitors. Analytical Biochemistry. 404: 186-92. PMID 20566370 DOI: 10.1016/j.ab.2010.05.033  0.92
2010 Yue Z. Autophagy in lurcher mice: Indicted but yet to be acquitted for the death of Purkinje cells Autophagy. 6: 571-572. PMID 20404573 DOI: 10.4161/auto.6.4.11957  0.92
2010 Li X, Patel JC, Wang J, Avshalumov MV, Nicholson C, Buxbaum JD, Elder GA, Rice ME, Yue Z. Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1788-97. PMID 20130188 DOI: 10.1523/JNEUROSCI.5604-09.2010  0.92
2009 Yue Z. LRRK2 in Parkinson's disease: In vivo models and approaches for understanding pathogenic roles Febs Journal. 276: 6445-6454. PMID 19804414 DOI: 10.1111/j.1742-4658.2009.07343.x  0.92
2009 Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nature Cell Biology. 11: 468-76. PMID 19270693 DOI: 10.1038/ncb1854  0.92
2009 Yue Z, Holstein GR, Chait BT, Wang QJ. Using genetic mouse models to study the biology and pathology of autophagy in the central nervous system. Methods in Enzymology. 453: 159-80. PMID 19216906 DOI: 10.1016/S0076-6879(08)04008-1  0.92
2009 Liu X, Yue Z. Recent patents and patent applications relating to mTOR pathway. Recent Patents On Dna & Gene Sequences. 3: 44-52. PMID 19149738 DOI: 10.2174/187221509787236192  0.92
2009 Lachenmayer L, Yue Z. Deficiency in striatal dopamine action: An omen for parkinson's disease? Neurochemistry: Molecular Aspects, Cellular Aspects and Clinical Applications. 225-235.  0.92
2008 Tang G, Yue Z, Talloczy Z, Goldman JE. Adaptive autophagy in Alexander disease-affected astrocytes. Autophagy. 4: 701-3. PMID 18414043  0.92
2008 Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE. Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. Human Molecular Genetics. 17: 1540-55. PMID 18276609 DOI: 10.1093/hmg/ddn042  0.92
2007 Yue Z. Regulation of neuronal autophagy in axon: Implication of autophagy in axonal function and dysfunction/degeneration Autophagy. 3: 139-141. PMID 17204855  0.92
1998 Yue Z, Shatkin AJ. Enzymatic and control functions of reovirus structural proteins. Current Topics in Microbiology and Immunology. 233: 31-56. PMID 9599920  0.92
1997 Yue Z, Shatkin AJ. Double-stranded RNA-dependent protein kinase (PKR) is regulated by reovirus structural proteins. Virology. 234: 364-71. PMID 9268168 DOI: 10.1006/viro.1997.8664  0.92
1996 Yue Z, Shatkin AJ. Regulated, stable expression and nuclear presence of reovirus double-stranded RNA-binding protein sigma3 in HeLa cells. Journal of Virology. 70: 3497-501. PMID 8648682  0.92
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