Paul J. Kenny - Publications

Scripps Florida, Jupiter, FL, United States 
 Icahn School of Medicine at Mount Sinai, New York, NY, United States 

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wills L, Ables JL, Braunscheidel KM, Caligiuri SPB, Elayouby KS, Fillinger C, Ishikawa M, Moen JK, Kenny PJ. Neurobiological Mechanisms of Nicotine Reward and Aversion. Pharmacological Reviews. 74: 271-310. PMID 35017179 DOI: 10.1124/pharmrev.121.000299  0.822
2021 Grossman YS, Fillinger C, Manganaro A, Voren G, Waldman R, Zou T, Janssen WG, Kenny PJ, Dumitriu D. Structure and function differences in the prelimbic cortex to basolateral amygdala circuit mediate trait vulnerability in a novel model of acute social defeat stress in male mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34799681 DOI: 10.1038/s41386-021-01229-6  0.757
2021 Bali P, Kenny PJ. Gene splicing SETs the scene for cocaine addiction. Neuron. 109: 2802-2804. PMID 34534452 DOI: 10.1016/j.neuron.2021.08.033  0.629
2021 Smith ACW, Jonkman S, Difeliceantonio AG, O'Connor RM, Ghoshal S, Romano MF, Everitt BJ, Kenny PJ. Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions. Nature Communications. 12: 5121. PMID 34433818 DOI: 10.1038/s41467-021-25460-3  0.656
2021 Wills L, Kenny PJ. Addiction-related neuroadaptations following chronic nicotine exposure. Journal of Neurochemistry. PMID 33742685 DOI: 10.1111/jnc.15356  0.393
2020 Elayouby KS, Ishikawa M, Dukes AJ, Smith ACW, Lu Q, Fowler CD, Kenny PJ. α3* Nicotinic acetylcholine receptors in the habenula-interpeduncular nucleus circuit regulate nicotine intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33380469 DOI: 10.1523/JNEUROSCI.0127-19.2020  0.775
2020 Lehmann VE, Kenny PJ. Hippocampal plasticity may drive cocaine relapse. Proceedings of the National Academy of Sciences of the United States of America. 117: 30003-30005. PMID 33199642 DOI: 10.1073/pnas.2020202117  0.749
2020 Caligiuri SPB, Kenny PJ. Habenular TCF7L2 links nicotine addiction to diabetes: the broad significance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32908242 DOI: 10.1038/s41386-020-00859-6  0.366
2020 Swinford-Jackson SE, O'Brien CP, Kenny PJ, Vanderschuren LJMJ, Unterwald EM, Pierce RC. The Persistent Challenge of Developing Addiction Pharmacotherapies. Cold Spring Harbor Perspectives in Medicine. PMID 32601131 DOI: 10.1101/cshperspect.a040311  0.401
2020 Picciotto MR, Kenny PJ. Mechanisms of Nicotine Addiction. Cold Spring Harbor Perspectives in Medicine. PMID 32341069 DOI: 10.1101/cshperspect.a039610  0.422
2020 Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, ... ... Kenny PJ, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201. PMID 32273471 DOI: 10.1126/Science.Aaw8806  0.427
2020 Antolin-Fontes B, Li K, Ables JL, Riad MH, Görlich A, Williams M, Wang C, Lipford SM, Dao M, Liu J, Molina H, Heintz N, Kenny PJ, Ibañez-Tallon I. The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake. Proceedings of the National Academy of Sciences of the United States of America. PMID 32098843 DOI: 10.1073/Pnas.1916132117  0.785
2019 Bali P, Kenny PJ. Transcriptional mechanisms of drug addiction
. Dialogues in Clinical Neuroscience. 21: 379-387. PMID 31949405 DOI: 10.31887/DCNS.2019.21.4/pkenny  0.651
2019 Duncan A, Heyer MP, Ishikawa M, Caligiuri SPB, Liu XA, Chen Z, Vittoria Micioni Di Bonaventura M, Elayouby KS, Ables JL, Howe WM, Bali P, Fillinger C, Williams M, O'Connor RM, Wang Z, ... ... Kenny PJ, et al. Habenular TCF7L2 links nicotine addiction to diabetes. Nature. 574: 372-377. PMID 31619789 DOI: 10.1038/S41586-019-1653-X  0.795
2019 Calipari ES, Godino A, Salery M, Damez-Werno DM, Cahill ME, Werner CT, Gancarz AM, Peck EG, Jlayer Z, Rabkin J, Landry JA, Smith ACW, Defilippi P, Kenny PJ, Hurd YL, et al. Synaptic microtubule-associated protein EB3 and SRC phosphorylation mediate structural and behavioral adaptations during withdrawal from cocaine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31092585 DOI: 10.1523/Jneurosci.0024-19.2019  0.415
2019 Liu XA, Kenny PJ. Cocaine-metabolizing skin grafts. Nature Biomedical Engineering. 3: 81-82. PMID 30944434 DOI: 10.1038/s41551-019-0355-x  0.357
2019 Ables J, Chen Z, Liu X, Oketokoun Z, Kenny P. F67. Exploring the Role of the Habenular-Interpeduncular Circuit in Affective States in Diabetes Biological Psychiatry. 85: S238-S239. DOI: 10.1016/J.Biopsych.2019.03.604  0.43
2018 Howe WM, Kenny PJ. Drug Addiction: Mechanisms of Nicotine Dependence Unmasked by Gene Editing. Current Biology : Cb. 28: R1205-R1207. PMID 30352192 DOI: 10.1016/j.cub.2018.09.003  0.395
2018 Chen Z, Kenny PJ. Endocannabinoid Signaling in the Habenula Regulates Adaptive Responses to Stress. Biological Psychiatry. 84: 553-554. PMID 30261976 DOI: 10.1016/J.Biopsych.2018.08.001  0.447
2018 Mathis V, Kenny PJ. From controlled to compulsive drug-taking: The role of the habenula in addiction. Neuroscience and Biobehavioral Reviews. PMID 29936111 DOI: 10.1016/j.neubiorev.2018.06.018  0.349
2018 DiFeliceantonio AG, Kenny PJ. Melanocortin 4 receptors switch reward to aversion. The Journal of Clinical Investigation. PMID 29911995 DOI: 10.1172/Jci121653  0.359
2018 Kenny PJ, Hoyer D, Koob GF. Animal Models of Addiction and Neuropsychiatric Disorders and Their Role in Drug Discovery: Honoring the Legacy of Athina Markou. Biological Psychiatry. PMID 29602521 DOI: 10.1016/J.Biopsych.2018.02.009  0.503
2018 Smith ACW, Kenny PJ. HDAC5 Regulates the Formation of Drug Memories. Trends in Molecular Medicine. PMID 29396145 DOI: 10.1016/j.molmed.2017.12.011  0.347
2018 Kenny P, Kamenecka T, Voren G, Duncan A, Howe M, Hollander J, Damez-Warno D, Lu Q, Bali P, Burli R, Gurrell I, Mather RJ, Brandon NJ. 11. Orexin-1 Receptor Antagonists as Novel Smoking Cessation Agents Biological Psychiatry. 83: S4-S5. DOI: 10.1016/J.Biopsych.2018.02.028  0.75
2017 Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I. Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158387 DOI: 10.1073/Pnas.1717506114  0.779
2017 Bobadilla AC, Heinsbroek JA, Gipson CD, Griffin WC, Fowler CD, Kenny PJ, Kalivas PW. Corticostriatal plasticity, neuronal ensembles, and regulation of drug-seeking behavior. Progress in Brain Research. 235: 93-112. PMID 29054293 DOI: 10.1016/Bs.Pbr.2017.07.013  0.729
2017 Wall TR, Henderson BJ, Voren G, Wageman CR, Deshpande P, Cohen BN, Grady SR, Marks MJ, Yohannes D, Kenny PJ, Bencherif M, Lester HA. TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors. Frontiers in Pharmacology. 8: 641. PMID 29033834 DOI: 10.3389/Fphar.2017.00641  0.805
2017 Smith ACW, Kenny PJ. MicroRNAs regulate synaptic plasticity underlying drug addiction. Genes, Brain, and Behavior. PMID 28873276 DOI: 10.1111/gbb.12424  0.361
2017 Tuesta LM, Chen Z, Duncan A, Fowler CD, Ishikawa M, Lee BR, Liu XA, Lu Q, Cameron M, Hayes MR, Kamenecka TM, Pletcher M, Kenny PJ. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nature Neuroscience. PMID 28368384 DOI: 10.1038/Nn.4540  0.804
2017 Liu XA, Kenny PJ. α5 nicotinic receptors link smoking to schizophrenia. Nature Medicine. 23: 277-278. PMID 28267713 DOI: 10.1038/nm.4300  0.393
2016 Lassi G, Taylor AE, Timpson NJ, Kenny PJ, Mather RJ, Eisen T, Munafò MR. The CHRNA5-A3-B4 Gene Cluster and Smoking: From Discovery to Therapeutics. Trends in Neurosciences. PMID 27871728 DOI: 10.1016/J.Tins.2016.10.005  0.365
2016 O'Connor RM, Gururajan A, Dinan TG, Kenny PJ, Cryan JF. All Roads Lead to the miRNome: miRNAs Have a Central Role in the Molecular Pathophysiology of Psychiatric Disorders. Trends in Pharmacological Sciences. PMID 27832923 DOI: 10.1016/J.Tips.2016.10.004  0.416
2016 Cryan JF, Kenny PJ. Obituary: Athina Markou PhD (1961-2015). Neuropharmacology. PMID 27793770 DOI: 10.1016/j.neuropharm.2016.10.023  0.367
2016 Ishikawa M, Kenny PJ. Crash course in pallidus-habenula signaling. Nature Neuroscience. 19: 981-3. PMID 27459402 DOI: 10.1038/Nn.4349  0.376
2015 Chen Z, Kenny PJ. Running on Empty: Leptin Signaling in VTA Regulates Reward from Physical Activity. Cell Metabolism. 22: 540-1. PMID 26445509 DOI: 10.1016/J.Cmet.2015.09.021  0.526
2015 Wang J, Kuryatov A, Jin Z, Norleans J, Kamenecka TM, Kenny PJ, Lindstrom J. A Novel α2/α4 Subtype-Selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting From the C-tail of an α Subunit. The Journal of Biological Chemistry. PMID 26432642 DOI: 10.1074/Jbc.M115.676551  0.349
2015 Heyer MP, Kenny PJ. Corticostriatal microRNAs in addiction. Brain Research. PMID 26253823 DOI: 10.1016/j.brainres.2015.07.047  0.643
2015 Wang J, Kuryatov A, Sriram A, Jin Z, Kamenecka TM, Kenny PJ, Lindstrom J. An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors. The Journal of Biological Chemistry. 290: 13907-18. PMID 25869137 DOI: 10.1074/Jbc.M115.646786  0.312
2014 Jonkman S, Kenny PJ. Promoting FOS to an enhanced position. Nature Neuroscience. 17: 1291-3. PMID 25254975 DOI: 10.1038/Nn.3819  0.611
2014 Heyer MP, Kenny PJ. MicroRNA-mediated repression combats depression. Neuron. 83: 253-4. PMID 25033172 DOI: 10.1016/j.neuron.2014.07.008  0.591
2014 Muschamp JW, Hollander JA, Thompson JL, Voren G, Hassinger LC, Onvani S, Kamenecka TM, Borgland SL, Kenny PJ, Carlezon WA. Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area. Proceedings of the National Academy of Sciences of the United States of America. 111: E1648-55. PMID 24706819 DOI: 10.1073/Pnas.1315542111  0.797
2014 Deng JV, Wan Y, Wang X, Cohen S, Wetsel WC, Greenberg ME, Kenny PJ, Calakos N, West AE. MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4519-27. PMID 24671997 DOI: 10.1523/Jneurosci.2821-13.2014  0.394
2014 Fowler CD, Kenny PJ. Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability. Neuropharmacology. 76: 533-44. PMID 24055497 DOI: 10.1016/j.neuropharm.2013.09.008  0.748
2013 Fowler CD, Tuesta L, Kenny PJ. Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice. Psychopharmacology. PMID 23958943 DOI: 10.1007/S00213-013-3235-1  0.813
2013 Kenny PJ, Voren G, Johnson PM. Dopamine D2 receptors and striatopallidal transmission in addiction and obesity. Current Opinion in Neurobiology. 23: 535-8. PMID 23726225 DOI: 10.1016/J.Conb.2013.04.012  0.782
2013 Bali P, Kenny PJ. MicroRNAs and Drug Addiction. Frontiers in Genetics. 4: 43. PMID 23717324 DOI: 10.3389/fgene.2013.00043  0.663
2013 Lotfipour S, Byun JS, Leach P, Fowler CD, Murphy NP, Kenny PJ, Gould TJ, Boulter J. Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7728-41. PMID 23637165 DOI: 10.1523/Jneurosci.4731-12.2013  0.725
2013 Hope BT, Skinner MK, Kenny PJ, Akbarian S. Exploring the epigenetics of cocaine resistance. Nature Medicine. 19: 136-7. PMID 23389607 DOI: 10.1038/Nm.3091  0.337
2013 Picciotto MR, Kenny PJ. Molecular mechanisms underlying behaviors related to nicotine addiction. Cold Spring Harbor Perspectives in Medicine. 3: a012112. PMID 23143843 DOI: 10.1101/cshperspect.a012112  0.448
2013 Jonkman S, Kenny PJ. Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 198-211. PMID 22968819 DOI: 10.1038/Npp.2012.120  0.67
2012 Harmey D, Griffin PR, Kenny PJ. Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 14: 1300-18. PMID 23024249 DOI: 10.1093/ntr/nts201  0.36
2012 Prins J, Kenny PJ, Doomernik I, Schreiber R, Olivier B, Mechiel Korte S. The triple reuptake inhibitor DOV 216,303 induces long-lasting enhancement of brain reward activity as measured by intracranial self-stimulation in rats. European Journal of Pharmacology. 693: 51-6. PMID 23010469 DOI: 10.1016/J.Ejphar.2012.07.047  0.377
2012 Heyer MP, Pani AK, Smeyne RJ, Kenny PJ, Feng G. Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10887-94. PMID 22875923 DOI: 10.1523/Jneurosci.1732-12.2012  0.668
2012 Hollander JA, Pham D, Fowler CD, Kenny PJ. Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence. Frontiers in Behavioral Neuroscience. 6: 47. PMID 22837742 DOI: 10.3389/fnbeh.2012.00047  0.808
2012 Pierce RC, O'Brien CP, Kenny PJ, Vanderschuren LJ. Rational development of addiction pharmacotherapies: successes, failures, and prospects. Cold Spring Harbor Perspectives in Medicine. 2: a012880. PMID 22675669 DOI: 10.1101/cshperspect.a012880  0.42
2012 Jiang R, Song X, Bali P, Smith A, Bayona CR, Lin L, Cameron MD, McDonald PH, Kenny PJ, Kamenecka TM. Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 3890-4. PMID 22617492 DOI: 10.1016/J.Bmcl.2012.04.122  0.61
2012 Im HI, Kenny PJ. MicroRNAs in neuronal function and dysfunction. Trends in Neurosciences. 35: 325-34. PMID 22436491 DOI: 10.1016/j.tins.2012.01.004  0.574
2012 Miller BH, Zeier Z, Xi L, Lanz TA, Deng S, Strathmann J, Willoughby D, Kenny PJ, Elsworth JD, Lawrence MS, Roth RH, Edbauer D, Kleiman RJ, Wahlestedt C. MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proceedings of the National Academy of Sciences of the United States of America. 109: 3125-30. PMID 22315408 DOI: 10.1073/Pnas.1113793109  0.537
2012 Fowler CD, Kenny PJ. Utility of genetically modified mice for understanding the neurobiology of substance use disorders. Human Genetics. 131: 941-57. PMID 22190154 DOI: 10.1007/s00439-011-1129-z  0.678
2012 Zhou L, Ghee SM, Chan C, Lin L, Cameron MD, Kenny PJ, See RE. Orexin-1 receptor mediation of cocaine seeking in male and female rats. The Journal of Pharmacology and Experimental Therapeutics. 340: 801-9. PMID 22186370 DOI: 10.1124/Jpet.111.187567  0.375
2012 Fowler CD, Kenny PJ. Habenular signaling in nicotine reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 306-7. PMID 22157872 DOI: 10.1038/npp.2011.197  0.734
2012 Hollander JA, Kenny PJ. Compulsive drug use and brain reward systems Drug Abuse and Addiction in Medical Illness: Causes, Consequences and Treatment. 2147483647: 63-72. DOI: 10.1007/978-1-4614-3375-0_5  0.465
2011 Ahmed SH, Kenny PJ. Cracking the molecular code of cocaine addiction. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 52: 309-20. PMID 23382145 DOI: 10.1093/ilar.52.3.309  0.434
2011 Kenny PJ. Common cellular and molecular mechanisms in obesity and drug addiction. Nature Reviews. Neuroscience. 12: 638-51. PMID 22011680 DOI: 10.1038/nrn3105  0.345
2011 Kenny PJ. 'Macrophage' cannabinoid receptor goes up in smoke. Nature Neuroscience. 14: 1100-2. PMID 21878924 DOI: 10.1038/nn.2912  0.397
2011 Tuesta LM, Fowler CD, Kenny PJ. Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior. Biochemical Pharmacology. 82: 984-95. PMID 21740894 DOI: 10.1016/J.Bcp.2011.06.026  0.825
2011 Fowler CD, Kenny PJ. Intravenous nicotine self-administration and cue-induced reinstatement in mice: effects of nicotine dose, rate of drug infusion and prior instrumental training. Neuropharmacology. 61: 687-98. PMID 21640128 DOI: 10.1016/j.neuropharm.2011.05.012  0.741
2011 Bali P, Im HI, Kenny PJ. Methylation, memory and addiction. Epigenetics : Official Journal of the Dna Methylation Society. 6: 671-4. PMID 21586900 DOI: 10.4161/epi.6.6.15905  0.689
2011 Kenny PJ. Reward mechanisms in obesity: new insights and future directions. Neuron. 69: 664-79. PMID 21338878 DOI: 10.1016/j.neuron.2011.02.016  0.336
2011 Fowler CD, Lu Q, Johnson PM, Marks MJ, Kenny PJ. Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. Nature. 471: 597-601. PMID 21278726 DOI: 10.1038/nature09797  0.806
2011 Kenny PJ. Tobacco dependence, the insular cortex and the hypocretin connection. Pharmacology, Biochemistry, and Behavior. 97: 700-7. PMID 20816891 DOI: 10.1016/j.pbb.2010.08.015  0.467
2010 Im HI, Hollander JA, Bali P, Kenny PJ. MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nature Neuroscience. 13: 1120-7. PMID 20711185 DOI: 10.1038/nn.2615  0.788
2010 Contet C, Whisler KN, Jarrell H, Kenny PJ, Markou A. Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice. Psychopharmacology. 212: 283-99. PMID 20668842 DOI: 10.1007/S00213-010-1950-4  0.776
2010 Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. The Journal of Experimental Medicine. 207: 1843-51. PMID 20643829 DOI: 10.1084/Jem.20100451  0.778
2010 Hollander JA, Im HI, Amelio AL, Kocerha J, Bali P, Lu Q, Willoughby D, Wahlestedt C, Conkright MD, Kenny PJ. Striatal microRNA controls cocaine intake through CREB signalling. Nature. 466: 197-202. PMID 20613834 DOI: 10.1038/Nature09202  0.805
2010 Johnson PM, Kenny PJ. Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nature Neuroscience. 13: 635-41. PMID 20348917 DOI: 10.1038/nn.2519  0.52
2010 Im H, Kenny PJ. Striatal microRNA controls compulsive cocaine-taking by regulating expression levels of the transcription factor MeCP2 F1000research. 1. DOI: 10.7490/F1000Research.50.1  0.576
2010 Schaefer A, Im H, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny P, O'Carroll D, Greengard P. Argonaute 2 in dopamine 2 receptor–expressing neurons regulates cocaine addiction The Journal of Cell Biology. 190: i4-i4. DOI: 10.1083/JCB1902OIA4  0.763
2010 Johnson PM, Kenny PJ. Corrigendum: Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats Nature Neuroscience. 13: 1033-1033. DOI: 10.1038/Nn0810-1033C  0.483
2009 Kenny PJ. Emerging therapeutic targets for the treatment of nicotine addiction. Expert Review of Clinical Pharmacology. 2: 221-5. PMID 24410700 DOI: 10.1586/ecp.09.6  0.393
2009 Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 106: 3507-12. PMID 19196972 DOI: 10.1073/Pnas.0805854106  0.306
2009 Kenny PJ, Chartoff E, Roberto M, Carlezon WA, Markou A. NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 266-81. PMID 18418357 DOI: 10.1038/Npp.2008.58  0.625
2008 Hollander JA, Lu Q, Cameron MD, Kamenecka TM, Kenny PJ. Insular hypocretin transmission regulates nicotine reward. Proceedings of the National Academy of Sciences of the United States of America. 105: 19480-5. PMID 19033203 DOI: 10.1073/pnas.0808023105  0.727
2008 Fowler CD, Arends MA, Kenny PJ. Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. Behavioural Pharmacology. 19: 461-84. PMID 18690103 DOI: 10.1097/FBP.0b013e32830c360e  0.744
2008 Johnson PM, Hollander JA, Kenny PJ. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, Biochemistry, and Behavior. 90: 409-15. PMID 18466962 DOI: 10.1016/j.pbb.2008.03.024  0.679
2007 Kenny PJ. Brain reward systems and compulsive drug use. Trends in Pharmacological Sciences. 28: 135-41. PMID 17276521 DOI: 10.1016/  0.36
2006 Kenny PJ, Chen SA, Kitamura O, Markou A, Koob GF. Conditioned withdrawal drives heroin consumption and decreases reward sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5894-900. PMID 16738231 DOI: 10.1523/JNEUROSCI.0740-06.2006  0.621
2006 Kenny PJ, Markou A. Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1203-11. PMID 16192981 DOI: 10.1038/sj.npp.1300905  0.62
2005 Boutrel B, Kenny PJ, Specio SE, Martin-Fardon R, Markou A, Koob GF, de Lecea L. Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 19168-73. PMID 16357203 DOI: 10.1073/Pnas.0507480102  0.668
2005 Paterson NE, Bruijnzeel AW, Kenny PJ, Wright CD, Froestl W, Markou A. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. 49: 953-62. PMID 16005474 DOI: 10.1016/j.neuropharm.2005.04.031  0.582
2005 Kenny PJ, Markou A. Conditioned nicotine withdrawal profoundly decreases the activity of brain reward systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6208-12. PMID 15987950 DOI: 10.1523/JNEUROSCI.4785-04.2005  0.595
2005 Kenny PJ, Boutrel B, Gasparini F, Koob GF, Markou A. Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology. 179: 247-54. PMID 15602687 DOI: 10.1007/S00213-004-2069-2  0.659
2005 Boutrel B, Kenny P, Specio S, Winsky-Sommerer R, Halfon O, Magistretti P, Markou A, Koob G, de Lecea L. A116 A KEY ROLE FOR HYPOCRETIN IN REGULATING BRAIN REWARD FUNCTION AND REINSTATEMENT FOR DRUG-SEEKING BEHAVIOR IN RATS Behavioural Pharmacology. 16: S60. DOI: 10.1097/00008877-200509001-00189  0.598
2005 Boutrel B, Kenny PJ, Markou A, Koob GF. Hypocretin and brain reward function Hypocretins: Integrators of Physiological Functions. 317-326. DOI: 10.1007/0-387-25446-3_21  0.535
2004 Kenny PJ, Markou A. The ups and downs of addiction: role of metabotropic glutamate receptors. Trends in Pharmacological Sciences. 25: 265-72. PMID 15120493 DOI: 10.1016/  0.547
2004 Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, O'Dell LE, Parsons LH, Sanna PP. Neurobiological mechanisms in the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews. 27: 739-49. PMID 15019424 DOI: 10.1016/J.Neubiorev.2003.11.007  0.61
2003 Kenny PJ, Paterson NE, Boutrel B, Semenova S, Harrison AA, Gasparini F, Koob GF, Skoubis PD, Markou A. Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. Annals of the New York Academy of Sciences. 1003: 415-8. PMID 14684476 DOI: 10.1196/Annals.1300.040  0.701
2003 Kenny PJ, Koob GF, Markou A. Conditioned facilitation of brain reward function after repeated cocaine administration. Behavioral Neuroscience. 117: 1103-7. PMID 14570559 DOI: 10.1037/0735-7044.117.5.1103  0.64
2003 Kenny PJ, Gasparini F, Markou A. Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats. The Journal of Pharmacology and Experimental Therapeutics. 306: 1068-76. PMID 12805481 DOI: 10.1124/jpet.103.052027  0.583
2003 Kenny PJ, Polis I, Koob GF, Markou A. Low dose cocaine self-administration transiently increases but high dose cocaine persistently decreases brain reward function in rats. The European Journal of Neuroscience. 17: 191-5. PMID 12534985 DOI: 10.1046/j.1460-9568.2003.02443.x  0.644
2002 Markou A, Kenny PJ. Neuroadaptations to chronic exposure to drugs of abuse: relevance to depressive symptomatology seen across psychiatric diagnostic categories. Neurotoxicity Research. 4: 297-313. PMID 12829420 DOI: 10.1080/10298420290023963  0.488
2002 Ahmed SH, Kenny PJ, Koob GF, Markou A. Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nature Neuroscience. 5: 625-6. PMID 12055635 DOI: 10.1038/nn872  0.659
2002 Markou A, Kenny P. Nicotine withdrawal and antidepressants: Monoaminergic and glutamatergic modulation of reward European Neuropsychopharmacology. 12: 88-89. DOI: 10.1016/S0924-977X(02)80014-1  0.548
2001 Kenny PJ, Markou A. Neurobiology of the nicotine withdrawal syndrome. Pharmacology, Biochemistry, and Behavior. 70: 531-49. PMID 11796152 DOI: 10.1016/S0091-3057(01)00651-7  0.617
2001 Cheeta S, Irvine EE, Kenny PJ, File SE. The dorsal raphé nucleus is a crucial structure mediating nicotine's anxiolytic effects and the development of tolerance and withdrawal responses. Psychopharmacology. 155: 78-85. PMID 11374339 DOI: 10.1007/s002130100681  0.433
2001 Kenny PJ, File SE, Rattray M. Nicotine regulates 5-HT(1A) receptor gene expression in the cerebral cortex and dorsal hippocampus. The European Journal of Neuroscience. 13: 1267-71. PMID 11285026 DOI: 10.1046/j.0953-816X.2001.01501.x  0.35
2000 Kenny PJ, File SE, Rattray M. Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain Research. Molecular Brain Research. 85: 234-8. PMID 11146126 DOI: 10.1016/S0169-328X(00)00246-1  0.381
2000 Cheeta S, Kenny PJ, File SE. Hippocampal and septal injections of nicotine and 8-OH-DPAT distinguish among different animal tests of anxiety. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 1053-67. PMID 11131172 DOI: 10.1016/S0278-5846(00)00129-9  0.309
2000 Kenny PJ, File SE, Neal MJ. Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release. Journal of Neurochemistry. 75: 2409-14. PMID 11080192 DOI: 10.1046/j.1471-4159.2000.0752409.x  0.34
2000 Cheeta S, Kenny PJ, File SE. The role of 5-HT1A receptors in mediating the anxiogenic effects of nicotine following lateral septal administration. The European Journal of Neuroscience. 12: 3797-802. PMID 11029650 DOI: 10.1046/j.1460-9568.2000.00246.x  0.423
2000 File SE, Kenny PJ, Cheeta S. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, Biochemistry, and Behavior. 66: 65-72. PMID 10837844 DOI: 10.1016/S0091-3057(00)00198-2  0.352
2000 File SE, Cheeta S, Kenny PJ. Neurobiological mechanisms by which nicotine mediates different types of anxiety. European Journal of Pharmacology. 393: 231-6. PMID 10771018 DOI: 10.1016/S0014-2999(99)00889-4  0.4
2000 Kenny PJ, Cheeta S, File SE. Anxiogenic effects of nicotine in the dorsal hippocampus are mediated by 5-HT1A and not by muscarinic M1 receptors. Neuropharmacology. 39: 300-7. PMID 10670425 DOI: 10.1016/S0028-3908(99)00114-8  0.414
1999 Ouagazzal AM, Kenny PJ, File SE. Stimulation of nicotinic receptors in the lateral septal nucleus increases anxiety. The European Journal of Neuroscience. 11: 3957-62. PMID 10583484 DOI: 10.1046/j.1460-9568.1999.00823.x  0.403
1999 Ouagazzal AM, Kenny PJ, File SE. Modulation of behaviour on trials 1 and 2 in the elevated plus-maze test of anxiety after systemic and hippocampal administration of nicotine. Psychopharmacology. 144: 54-60. PMID 10379624 DOI: 10.1007/s002130050976  0.38
1999 Kenny PJ, Cheeta S, Ouagazzal A-, Gonzalez LE, File SE. Neurochemical mechanisms by which dorsal hippocampal nicotinic acetylcholine receptors modulate anxiety European Neuropsychopharmacology. 9: 303. DOI: 10.1016/S0924-977X(99)80389-7  0.405
1998 File SE, Kenny PJ, Ouagazzal AM. Bimodal modulation by nicotine of anxiety in the social interaction test: role of the dorsal hippocampus. Behavioral Neuroscience. 112: 1423-9. PMID 9926824 DOI: 10.1037/0735-7044.112.6.1423  0.364
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