Ana M. Cuervo - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Cell Biology, Neuroscience Biology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Guerrero-Ros I, Clement CC, Reynolds CA, Patel B, Santambrogio L, Cuervo AM, Macian F. The negative effect of lipid challenge on autophagy inhibits T cell responses. Autophagy. PMID 30982401 DOI: 10.1080/15548627.2019.1606635  0.44
2019 Hernandez I, Luna G, Rauch JN, Reis SA, Giroux M, Karch CM, Boctor D, Sibih YE, Storm NJ, Diaz A, Kaushik S, Zekanowski C, Kang AA, Hinman CR, Cerovac V, ... ... Cuervo AM, et al. A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy. Science Translational Medicine. 11. PMID 30918111 DOI: 10.1126/scitranslmed.aat3005  1
2016 Morozova K, Clement CC, Kaushik S, Stiller B, Arias E, Ahmad A, Rauch JN, Chatterjee V, Melis C, Scharf B, Gestwicki JE, Cuervo AM, Zuiderweg ER, Santambrogio L. Hsc-70 Structural and Biological Interaction with Phosphatidylserine in Endosomal Microautophagy. The Journal of Biological Chemistry. PMID 27405763 DOI: 10.1074/jbc.M116.736744  1
2016 Mitchell SJ, Madrigal-Matute J, Scheibye-Knudsen M, Fang E, Aon M, González-Reyes JA, Cortassa S, Kaushik S, Gonzalez-Freire M, Patel B, Wahl D, Ali A, Calvo-Rubio M, Burón MI, Guiterrez V, ... ... Cuervo AM, et al. Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice. Cell Metabolism. 23: 1093-1112. PMID 27304509 DOI: 10.1016/j.cmet.2016.05.027  1
2016 Kaushik S, Cuervo AM. AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA. Autophagy. 12: 432-8. PMID 26902588 DOI: 10.1080/15548627.2015.1124226  1
2015 Kaushik S, Cuervo AM. Proteostasis and aging. Nature Medicine. 21: 1406-15. PMID 26646497 DOI: 10.1038/nm.4001  1
2015 Kaushik S, Cuervo AM. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nature Cell Biology. 17: 759-70. PMID 25961502 DOI: 10.1038/ncb3166  1
2015 Morozova K, Sridhar S, Zolla V, Clement CC, Scharf B, Verzani Z, Diaz A, Larocca JN, Hajjar KA, Cuervo AM, Santambrogio L. Corrigendum: Annexin A2 promotes phagophore assembly by enhancing Atg16⁺ vesicle biogenesis and homotypic fusion. Nature Communications. 6: 6816. PMID 25817270 DOI: 10.1038/ncomms7816  1
2015 Morozova K, Sidhar S, Zolla V, Clement CC, Scharf B, Verzani Z, Diaz A, Larocca JN, Hajjar KA, Cuervo AM, Santambrogio L. Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion. Nature Communications. 6: 5856. PMID 25597631 DOI: 10.1038/ncomms6856  1
2014 Yang DS, Stavrides P, Saito M, Kumar A, Rodriguez-Navarro JA, Pawlik M, Huo C, Walkley SU, Saito M, Cuervo AM, Nixon RA. Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits. Brain : a Journal of Neurology. 137: 3300-18. PMID 25270989 DOI: 10.1093/brain/awu278  1
2013 Pampliega O, Orhon I, Patel B, Sridhar S, Díaz-Carretero A, Beau I, Codogno P, Satir BH, Satir P, Cuervo AM. Functional interaction between autophagy and ciliogenesis. Nature. 502: 194-200. PMID 24089209 DOI: 10.1038/nature12639  1
2013 Anguiano J, Garner TP, Mahalingam M, Das BC, Gavathiotis E, Cuervo AM. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives. Nature Chemical Biology. 9: 374-82. PMID 23584676 DOI: 10.1038/nchembio.1230  1
2013 Sridhar S, Patel B, Aphkhazava D, Macian F, Santambrogio L, Shields D, Cuervo AM. The lipid kinase PI4KIIIβ preserves lysosomal identity. The Embo Journal. 32: 324-39. PMID 23258225 DOI: 10.1038/emboj.2012.341  1
2012 Kaushik S, Cuervo AM. Chaperones in autophagy. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 66: 484-93. PMID 23059540 DOI: 10.1016/j.phrs.2012.10.002  1
2012 Cannizzo ES, Clement CC, Morozova K, Valdor R, Kaushik S, Almeida LN, Follo C, Sahu R, Cuervo AM, Macian F, Santambrogio L. Age-related oxidative stress compromises endosomal proteostasis. Cell Reports. 2: 136-49. PMID 22840404 DOI: 10.1016/j.celrep.2012.06.005  1
2012 Kaushik S, Cuervo AM. Chaperone-mediated autophagy: a unique way to enter the lysosome world. Trends in Cell Biology. 22: 407-17. PMID 22748206 DOI: 10.1016/j.tcb.2012.05.006  1
2012 Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C. Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Human Molecular Genetics. 21: 2245-62. PMID 22337954 DOI: 10.1093/hmg/dds040  1
2012 Rodriguez-Navarro JA, Kaushik S, Koga H, Dall'Armi C, Shui G, Wenk MR, Di Paolo G, Cuervo AM. Inhibitory effect of dietary lipids on chaperone-mediated autophagy. Proceedings of the National Academy of Sciences of the United States of America. 109: E705-14. PMID 22331875 DOI: 10.1073/pnas.1113036109  1
2012 Sridhar S, Botbol Y, Macian F, Cuervo AM. Autophagy and disease: always two sides to a problem. The Journal of Pathology. 226: 255-73. PMID 21990109 DOI: 10.1002/path.3025  1
2011 Koga H, Martinez-Vicente M, Arias E, Kaushik S, Sulzer D, Cuervo AM. Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 18492-505. PMID 22171050 DOI: 10.1523/JNEUROSCI.3219-11.2011  1
2011 Kon M, Kiffin R, Koga H, Chapochnick J, Macian F, Varticovski L, Cuervo AM. Chaperone-mediated autophagy is required for tumor growth. Science Translational Medicine. 3: 109ra117. PMID 22089453 DOI: 10.1126/scitranslmed.3003182  1
2011 Kaushik S, Rodriguez-Navarro JA, Arias E, Kiffin R, Sahu S, Schwartz GJ, Cuervo AM, Singh R. Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance. Cell Metabolism. 14: 173-83. PMID 21803288 DOI: 10.1016/j.cmet.2011.06.008  1
2011 Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson DW, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, ... ... Cuervo AM, et al. Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis. Autophagy. 7: 788-9. PMID 21464620 DOI: 10.4161/auto.7.7.15596  1
2011 Santambrogio L, Cuervo AM. Chasing the elusive mammalian microautophagy. Autophagy. 7: 652-4. PMID 21460618 DOI: 10.4161/auto.7.6.15287  1
2011 Kaushik S, Bandyopadhyay U, Sridhar S, Kiffin R, Martinez-Vicente M, Kon M, Orenstein SJ, Wong E, Cuervo AM. Chaperone-mediated autophagy at a glance. Journal of Cell Science. 124: 495-9. PMID 21282471 DOI: 10.1242/jcs.073874  1
2011 Sahu R, Kaushik S, Clement CC, Cannizzo ES, Scharf B, Follenzi A, Potolicchio I, Nieves E, Cuervo AM, Santambrogio L. Microautophagy of cytosolic proteins by late endosomes. Developmental Cell. 20: 131-9. PMID 21238931 DOI: 10.1016/j.devcel.2010.12.003  1
2011 Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson D, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, ... ... Cuervo AM, et al. Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits. Brain : a Journal of Neurology. 134: 258-77. PMID 21186265 DOI: 10.1093/brain/awq341  1
2011 Koga H, Kaushik S, Cuervo AM. Protein homeostasis and aging: The importance of exquisite quality control Ageing Research Reviews. 10: 205-215. PMID 20152936 DOI: 10.1016/j.arr.2010.02.001  1
2010 Kaushik S, Singh R, Cuervo AM. Autophagic pathways and metabolic stress. Diabetes, Obesity & Metabolism. 12: 4-14. PMID 21029294 DOI: 10.1111/j.1463-1326.2010.01263.x  1
2010 Bandyopadhyay U, Sridhar S, Kaushik S, Kiffin R, Cuervo AM. Identification of regulators of chaperone-mediated autophagy. Molecular Cell. 39: 535-47. PMID 20797626 DOI: 10.1016/j.molcel.2010.08.004  1
2010 Koga H, Kaushik S, Cuervo AM. Inhibitory effect of intracellular lipid load on macroautophagy. Autophagy. 6: 825-7. PMID 20647740 DOI: 10.1096/fj.09-144519  1
2010 Rothenberg C, Srinivasan D, Mah L, Kaushik S, Peterhoff CM, Ugolino J, Fang S, Cuervo AM, Nixon RA, Monteiro MJ. Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy. Human Molecular Genetics. 19: 3219-32. PMID 20529957 DOI: 10.1093/hmg/ddq231  1
2010 Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik S, de Vries R, Arias E, Harris S, Sulzer D, Cuervo AM. Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease. Nature Neuroscience. 13: 567-76. PMID 20383138 DOI: 10.1038/nn.2528  1
2010 Koga H, Kaushik S, Cuervo AM. Altered lipid content inhibits autophagic vesicular fusion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3052-65. PMID 20375270 DOI: 10.1096/fj.09-144519  1
2010 Lee JY, Koga H, Kawaguchi Y, Tang W, Wong E, Gao YS, Pandey UB, Kaushik S, Tresse E, Lu J, Taylor JP, Cuervo AM, Yao TP. HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. The Embo Journal. 29: 969-80. PMID 20075865 DOI: 10.1038/emboj.2009.405  1
2010 Kon M, Cuervo AM. Chaperone-mediated autophagy in health and disease. Febs Letters. 584: 1399-404. PMID 20026330 DOI: 10.1016/j.febslet.2009.12.025  1
2010 Wang Y, Martinez-Vicente M, Krüger U, Kaushik S, Wong E, Mandelkow EM, Cuervo AM, Mandelkow E. Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation. Autophagy. 6: 182-3. PMID 20023429 DOI: 10.4161/auto.6.1.10815  1
2009 Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes & Development. 23: 2294-306. PMID 19762508 DOI: 10.1101/gad.1830709  1
2009 Wang Y, Martinez-Vicente M, Krüger U, Kaushik S, Wong E, Mandelkow EM, Cuervo AM, Mandelkow E. Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Human Molecular Genetics. 18: 4153-70. PMID 19654187 DOI: 10.1093/hmg/ddp367  1
2009 Rubinsztein DC, Cuervo AM, Ravikumar B, Sarkar S, Korolchuk V, Kaushik S, Klionsky DJ. In search of an "autophagomometer". Autophagy. 5: 585-9. PMID 19411822  1
2009 Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, Tanaka K, Cuervo AM, Czaja MJ. Autophagy regulates lipid metabolism. Nature. 458: 1131-5. PMID 19339967 DOI: 10.1038/nature07976  1
2009 Morimoto RI, Cuervo AM. Protein homeostasis and aging: taking care of proteins from the cradle to the grave. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 167-70. PMID 19228787 DOI: 10.1093/gerona/gln071  1
2009 Kaushik S, Cuervo AM. Methods to monitor chaperone-mediated autophagy. Methods in Enzymology. 452: 297-324. PMID 19200890 DOI: 10.1016/S0076-6879(08)03619-7  1
2008 Bandyopadhyay U, Kaushik S, Varticovski L, Cuervo AM. The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane. Molecular and Cellular Biology. 28: 5747-63. PMID 18644871 DOI: 10.1128/MCB.02070-07  1
2008 Kaushik S, Cuervo AM. Chaperone-mediated autophagy. Methods in Molecular Biology (Clifton, N.J.). 445: 227-44. PMID 18425454 DOI: 10.1007/978-1-59745-157-4_15  1
2008 Massey AC, Follenzi A, Kiffin R, Zhang C, Cuervo AM. Early cellular changes after blockage of chaperone-mediated autophagy. Autophagy. 4: 442-56. PMID 18253088  1
2007 Kaushik S, Kiffin R, Cuervo AM. Chaperone-mediated autophagy and aging: a novel regulatory role of lipids revealed. Autophagy. 3: 387-9. PMID 17438364  1
2007 Kiffin R, Kaushik S, Zeng M, Bandyopadhyay U, Zhang C, Massey AC, Martinez-Vicente M, Cuervo AM. Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age. Journal of Cell Science. 120: 782-91. PMID 17284523 DOI: 10.1242/jcs.001073  1
2006 Massey AC, Kiffin R, Cuervo AM. Autophagic defects in aging: looking for an "emergency exit"? Cell Cycle (Georgetown, Tex.). 5: 1292-6. PMID 16760669 DOI: 10.4161/cc.5.12.2865  1
2006 Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM. Consequences of the selective blockage of chaperone-mediated autophagy. Proceedings of the National Academy of Sciences of the United States of America. 103: 5805-10. PMID 16585521 DOI: 10.1073/pnas.0507436103  1
2006 Kiffin R, Bandyopadhyay U, Cuervo AM. Oxidative stress and autophagy. Antioxidants & Redox Signaling. 8: 152-62. PMID 16487049 DOI: 10.1089/ars.2006.8.152  1
2004 Kiffin R, Christian C, Knecht E, Cuervo AM. Activation of chaperone-mediated autophagy during oxidative stress. Molecular Biology of the Cell. 15: 4829-40. PMID 15331765 DOI: 10.1091/mbc.E04-06-0477  1
2004 Massey A, Kiffin R, Cuervo AM. Pathophysiology of chaperone-mediated autophagy. The International Journal of Biochemistry & Cell Biology. 36: 2420-34. PMID 15325582 DOI: 10.1016/j.biocel.2004.04.010  1
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