David E. Kang, PhD - Publications

1993-2004 Neurosciences University of California, San Diego, La Jolla, CA 
 2004-2012 Neurosciences University of California, San Diego, La Jolla, CA 
 2009-2012 Biomedical Sciences Seoul National Unversity 
 2012- Molecular Medicine USF Health Byrd Alzheimer's Institute 
Alzheimer's disease, amyloid, presenilin, tau, TDP-43, catenin, LRP, CHCHD10, mitochondria, synapse

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu T, Woo JA, Yan Y, LePochat P, Bukhari MZ, Kang DE. Dual role of cofilin in APP trafficking and amyloid-β clearance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901268R. PMID 31646885 DOI: 10.1096/fj.201901268R  0.76
2019 Kang DE, Woo JA. Cofilin, a Master Node Regulating Cytoskeletal Pathogenesis in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31594228 DOI: 10.3233/JAD-190585  0.76
2019 Woo JA, Liu T, Fang CC, Cazzaro S, Kee T, LePochat P, Yrigoin K, Penn C, Zhao X, Wang X, Liggett SB, Kang DE. Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics. Communications Biology. 2: 112. PMID 30911686 DOI: 10.1038/s42003-019-0359-9  0.76
2017 Woo JA, Liu T, Zhao X, Trotter C, Yrigoin K, Cazzaro S, Narvaez E, Khan H, Witas R, Bukhari A, Makati K, Wang X, Dickey C, Kang DE. Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes. Human Molecular Genetics. 26: 3973-3988. PMID 29016855 DOI: 10.1093/hmg/ddx284  0.76
2017 Liu T, Wang F, LePochat P, Woo JA, Bukhari MZ, Hong KW, Trotter C, Kang DE. Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation. Scientific Reports. 7: 11532. PMID 28912445 DOI: 10.1038/s41598-017-09996-3  0.76
2017 Woo JA, Liu T, Trotter C, Fang CC, De Narvaez E, LePochat P, Maslar D, Bukhari A, Zhao X, Deonarine A, Westerheide SD, Kang DE. Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity. Nature Communications. 8: 15558. PMID 28585542 DOI: 10.1038/ncomms15558  0.76
2014 Wang R, Palavicini JP, Wang H, Maiti P, Bianchi E, Xu S, Lloyd BN, Dawson-Scully K, Kang DE, Lakshmana MK. RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer's disease. Neurobiology of Disease. 69: 169-79. PMID 24892886 DOI: 10.1016/j.nbd.2014.05.029  0.52
2013 Almenar-Queralt A, Kim SN, Benner C, Herrera CM, Kang DE, Garcia-Bassets I, Goldstein LS. Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation. The Journal of Biological Chemistry. 288: 35222-36. PMID 24145027 DOI: 10.1074/jbc.M113.513705  0.52
2013 Jeon JP, Roh SE, Wie J, Kim J, Kim H, Lee KP, Yang D, Jeon JH, Cho NH, Kim IG, Kang DE, Kim HJ, So I. Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron Cell Calcium. 54: 307-319. PMID 24011658 DOI: 10.1016/j.ceca.2013.07.006  0.52
2013 Roh SE, Woo JA, Lakshmana MK, Uhlar C, Ankala V, Boggess T, Liu T, Hong YH, Mook-Jung I, Kim SJ, Kang DE. Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4776-89. PMID 23982146 DOI: 10.1096/fj.13-234765  0.52
2013 Palavicini JP, Lloyd BN, Hayes CD, Bianchi E, Kang DE, Dawson-Scully K, Lakshmana MK. RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice. Plos One. 8: e66908. PMID 23840553 DOI: 10.1371/journal.pone.0066908  0.52
2012 Shilling D, Mak DO, Kang DE, Foskett JK. Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels. The Journal of Biological Chemistry. 287: 10933-44. PMID 22311977 DOI: 10.1074/jbc.M111.300491  0.52
2012 Lakshmana MK, Hayes CD, Bennett SP, Bianchi E, Reddy KM, Koo EH, Kang DE. Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2072-83. PMID 22294787 DOI: 10.1096/fj.11-196709  0.52
2012 Woo JA, Roh SE, Lakshmana MK, Kang DE. Pivotal role of RanBP9 in integrin-dependent focal adhesion signaling and assembly. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1672-81. PMID 22223749 DOI: 10.1096/fj.11-194423  0.76
2011 Kang DE, Roh SE, Woo JA, Liu T, Bu JH, Jung AR, Lim Y. The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders. Experimental Neurobiology. 20: 67-80. PMID 22110363 DOI: 10.5607/en.2011.20.2.67  0.76
2010 Cheung KH, Mei L, Mak DO, Hayashi I, Iwatsubo T, Kang DE, Foskett JK. Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons. Science Signaling. 3: ra22. PMID 20332427 DOI: 10.1126/scisignal.2000818  0.52
2010 Lakshmana MK, Chung JY, Wickramarachchi S, Tak E, Bianchi E, Koo EH, Kang DE. A fragment of the scaffolding protein RanBP9 is increased in Alzheimer's disease brains and strongly potentiates amyloid-beta peptide generation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 119-27. PMID 19729516 DOI: 10.1096/fj.09-136457  0.52
2009 Lakshmana MK, Yoon IS, Chen E, Bianchi E, Koo EH, Kang DE. Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation. The Journal of Biological Chemistry. 284: 11863-72. PMID 19251705 DOI: 10.1074/jbc.M807345200  0.52
2008 Kwan P, Poon WS, Ng HK, Kang DE, Wong V, Ng PW, Lui CH, Sin NC, Wong KS, Baum L. Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression. Pharmacogenetics and Genomics. 18: 989-98. PMID 18784617 DOI: 10.1097/FPC.0b013e3283117d67  0.52
2008 Lakshmana MK, Chen E, Yoon IS, Kang DE. C-terminal 37 residues of LRP promote the amyloidogenic processing of APP independent of FE65. Journal of Cellular and Molecular Medicine. 12: 2665-74. PMID 18373737 DOI: 10.1111/j.1582-4934.2008.00320.x  0.52
2007 Repetto E, Yoon IS, Zheng H, Kang DE. Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway. The Journal of Biological Chemistry. 282: 31504-16. PMID 17716970 DOI: 10.1074/jbc.M704273200  0.52
2007 Yoon IS, Chen E, Busse T, Repetto E, Lakshmana MK, Koo EH, Kang DE. Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2742-52. PMID 17463224 DOI: 10.1096/fj.07-8114com  0.52
2005 Kang DE, Yoon IS, Repetto E, Busse T, Yermian N, Ie L, Koo EH. Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling. The Journal of Biological Chemistry. 280: 31537-47. PMID 16014629 DOI: 10.1074/jbc.M500833200  0.52
2005 Chevallier NL, Soriano S, Kang DE, Masliah E, Hu G, Koo EH. Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation. The American Journal of Pathology. 167: 151-9. PMID 15972961 DOI: 10.1016/S0002-9440(10)62962-8  0.52
2005 Yoon IS, Pietrzik CU, Kang DE, Koo EH. Sequences from the low density lipoprotein receptor-related protein (LRP) cytoplasmic domain enhance amyloid beta protein production via the beta-secretase pathway without altering amyloid precursor protein/LRP nuclear signaling. The Journal of Biological Chemistry. 280: 20140-7. PMID 15772078 DOI: 10.1074/jbc.M413729200  0.52
2002 Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell. 110: 751-62. PMID 12297048 DOI: 10.1016/S0092-8674(02)00970-4  0.52
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