Scott T. Brady, PhD - Publications

Affiliations: 
Antaomy and Cell Biology University of Illinois at Chicago, Chicago, IL, United States 

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Combs B, Christensen KR, Richards C, Kneynsberg A, Mueller RL, Morris SL, Morfini G, Brady ST, Kanaan NM. FTLD mutant tau impairs axonal transport through a protein phosphatase 1γ-dependent mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34607969 DOI: 10.1523/JNEUROSCI.1914-20.2021  0.756
2021 Richards A, Berth SH, Brady S, Morfini G. Engagement of Neurotropic Viruses in Fast Axonal Transport: Mechanisms, Potential Role of Host Kinases and Implications for Neuronal Dysfunction. Frontiers in Cellular Neuroscience. 15: 684762. PMID 34234649 DOI: 10.3389/fncel.2021.684762  0.416
2021 Mueller RL, Combs B, Alhadidy MM, Brady ST, Morfini GA, Kanaan NM. Tau: A Signaling Hub Protein. Frontiers in Molecular Neuroscience. 14: 647054. PMID 33815057 DOI: 10.3389/fnmol.2021.647054  0.657
2020 Morris SL, Tsai MY, Aloe S, Bechberger K, König S, Morfini G, Brady ST. Defined Tau Phosphospecies Differentially Inhibit Fast Axonal Transport Through Activation of Two Independent Signaling Pathways. Frontiers in Molecular Neuroscience. 13: 610037. PMID 33568975 DOI: 10.3389/fnmol.2020.610037  0.381
2019 Combs B, Mueller RL, Morfini G, Brady ST, Kanaan NM. Tau and Axonal Transport Misregulation in Tauopathies. Advances in Experimental Medicine and Biology. 1184: 81-95. PMID 32096030 DOI: 10.1007/978-981-32-9358-8_7  0.813
2019 Gatto RG, Ye AQ, Colon-Perez L, Mareci TH, Lysakowski A, Price SD, Brady ST, Karaman M, Morfini G, Magin RL. Detection of axonal degeneration in a mouse model of Huntington's disease: comparison between diffusion tensor imaging and anomalous diffusion metrics. Magma (New York, N.Y.). PMID 30771034 DOI: 10.1007/S10334-019-00742-6  0.333
2017 Zamponi E, Buratti F, Cataldi G, Caicedo HH, Song Y, Jungbauer LM, LaDu MJ, Bisbal M, Lorenzo A, Ma J, Helguera PR, Morfini GA, Brady ST, Pigino GF. Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2. Plos One. 12: e0188340. PMID 29261664 DOI: 10.1371/Journal.Pone.0188340  0.835
2017 Brady ST, Morfini GA. Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases. Neurobiology of Disease. PMID 28411118 DOI: 10.1016/J.Nbd.2017.04.010  0.519
2017 Leo L, Weissmann C, Burns M, Kang M, Song Y, Qiang L, Brady ST, Baas PW, Morfini G. Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism involving casein kinase 2 activation. Human Molecular Genetics. PMID 28398512 DOI: 10.1093/Hmg/Ddx125  0.778
2017 Sama RR, Fallini C, Gatto R, McKeon JE, Song Y, Rotunno MS, Penaranda S, Abdurakhmanov I, Landers JE, Morfini G, Brady ST, Bosco DA. ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation. Scientific Reports. 7: 115. PMID 28273913 DOI: 10.1038/S41598-017-00091-1  0.802
2016 Berth SH, Mesnard-Hoaglin N, Wang B, Kim H, Song Y, Sapar M, Morfini G, Brady ST. HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways. Asn Neuro. 8. PMID 27872270 DOI: 10.1177/1759091416679073  0.826
2016 Cox K, Combs B, Abdelmesih B, Morfini G, Brady ST, Kanaan NM. Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition. Neurobiology of Aging. 47: 113-126. PMID 27574109 DOI: 10.1016/J.Neurobiolaging.2016.07.015  0.733
2016 Kurowska Z, Kordower JH, Stoessl AJ, Burke R, Brundin P, Yue Z, Brady ST, Milbrandt J, Trapp BD, Sherer TB, Medicetty S. Is Axonal Degeneration a Key Early Event in Parkinson's Disease? Journal of Parkinson's Disease. PMID 27497486 DOI: 10.3233/Jpd-160881  0.561
2016 Tiernan CT, Combs B, Cox K, Morfini G, Brady ST, Counts SE, Kanaan NM. Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. Experimental Neurology. PMID 27373205 DOI: 10.1016/J.Expneurol.2016.06.030  0.721
2016 Moreno H, Morfini G, Buitrago L, Ujlaki G, Choi S, Yu E, Moreira JE, Avila J, Brady ST, Pant H, Sugimori M, Llinás RR. Tau Pathology Mediated Presynaptic Dysfunction. Neuroscience. PMID 27012611 DOI: 10.1016/J.Neuroscience.2016.03.044  0.425
2016 Song Y, Kang M, Morfini G, Brady ST. Fast axonal transport in isolated axoplasm from the squid giant axon. Methods in Cell Biology. 131: 331-48. PMID 26794522 DOI: 10.1016/Bs.Mcb.2015.07.004  0.831
2016 Kang M, Baker L, Song Y, Brady ST, Morfini G. Biochemical analysis of axon-specific phosphorylation events using isolated squid axoplasms. Methods in Cell Biology. 131: 199-216. PMID 26794515 DOI: 10.1016/Bs.Mcb.2015.06.003  0.84
2015 Caicedo HH, Brady ST. Microfluidics: The Challenge Is to Bridge the Gap Instead of Looking for a 'Killer App'. Trends in Biotechnology. PMID 26603287 DOI: 10.1016/J.Tibtech.2015.10.003  0.682
2015 Gatto RG, Chu Y, Ye AQ, Price SD, Tavassoli E, Buenaventura A, Brady ST, Magin RL, Kordower JH, Morfini GA. Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease. Human Molecular Genetics. 24: 5285-98. PMID 26123489 DOI: 10.1093/Hmg/Ddv248  0.568
2015 Berth S, Caicedo HH, Sarma T, Morfini G, Brady ST. Internalization and axonal transport of the HIV glycoprotein gp120. Asn Neuro. 7. PMID 25636314 DOI: 10.1177/1759091414568186  0.782
2015 Song Y, Brady ST. Post-translational modifications of tubulin: pathways to functional diversity of microtubules. Trends in Cell Biology. 25: 125-36. PMID 25468068 DOI: 10.1016/J.Tcb.2014.10.004  0.736
2014 Song Y, Brady ST. Stabilization of neuronal connections and the axonal cytoskeleton. Bioarchitecture. 4: 22-4. PMID 24492417 DOI: 10.4161/bioa.28080  0.803
2013 Song Y, Brady ST. Analysis of microtubules in isolated axoplasm from the squid giant axon. Methods in Cell Biology. 115: 125-37. PMID 23973070 DOI: 10.1016/B978-0-12-407757-7.00009-8  0.832
2013 Morfini GA, Bosco DA, Brown H, Gatto R, Kaminska A, Song Y, Molla L, Baker L, Marangoni MN, Berth S, Tavassoli E, Bagnato C, Tiwari A, Hayward LJ, Pigino GF, ... ... Brady ST, et al. Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase. Plos One. 8: e65235. PMID 23776455 DOI: 10.1371/Journal.Pone.0065235  0.825
2013 Cantuti Castelvetri L, Givogri MI, Hebert A, Smith B, Song Y, Kaminska A, Lopez-Rosas A, Morfini G, Pigino G, Sands M, Brady ST, Bongarzone ER. The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10048-56. PMID 23761900 DOI: 10.1523/Jneurosci.0217-13.2013  0.845
2013 LaPointe NE, Morfini G, Brady ST, Feinstein SC, Wilson L, Jordan MA. Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy. Neurotoxicology. 37: 231-9. PMID 23711742 DOI: 10.1016/J.Neuro.2013.05.008  0.623
2013 Song Y, Kirkpatrick LL, Schilling AB, Helseth DL, Chabot N, Keillor JW, Johnson GV, Brady ST. Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubules. Neuron. 78: 109-23. PMID 23583110 DOI: 10.1016/J.Neuron.2013.01.036  0.805
2013 Song Y, Nagy M, Ni W, Tyagi NK, Fenton WA, López-Giráldez F, Overton JD, Horwich AL, Brady ST. Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm. Proceedings of the National Academy of Sciences of the United States of America. 110: 5428-33. PMID 23509252 DOI: 10.1073/Pnas.1303279110  0.824
2013 Kanaan NM, Pigino GF, Brady ST, Lazarov O, Binder LI, Morfini GA. Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system. Experimental Neurology. 246: 44-53. PMID 22721767 DOI: 10.1016/J.Expneurol.2012.06.003  0.769
2013 Hennigan RF, Moon CA, Parysek LM, Monk KR, Morfini G, Berth S, Brady S, Ratner N. The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway. Oncogene. 32: 1135-43. PMID 22525268 DOI: 10.1038/Onc.2012.135  0.387
2012 Chu Y, Morfini GA, Langhamer LB, He Y, Brady ST, Kordower JH. Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease. Brain : a Journal of Neurology. 135: 2058-73. PMID 22719003 DOI: 10.1093/Brain/Aws133  0.528
2012 Kanaan NM, Morfini G, Pigino G, LaPointe NE, Andreadis A, Song Y, Leitman E, Binder LI, Brady ST. Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport. Neurobiology of Aging. 33: 826.e15-30. PMID 21794954 DOI: 10.1016/J.Neurobiolaging.2011.06.006  0.815
2011 Patterson KR, Ward SM, Combs B, Voss K, Kanaan NM, Morfini G, Brady ST, Gamblin TC, Binder LI. Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport. Biochemistry. 50: 10300-10. PMID 22039833 DOI: 10.1021/Bi2009147  0.703
2011 Kanaan NM, Morfini GA, LaPointe NE, Pigino GF, Patterson KR, Song Y, Andreadis A, Fu Y, Brady ST, Binder LI. Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9858-68. PMID 21734277 DOI: 10.1523/Jneurosci.0560-11.2011  0.862
2011 Brady S. The curious case of the soluble protein. Developmental Cell. 20: 581-2. PMID 21571216 DOI: 10.1016/j.devcel.2011.05.003  0.475
2011 Smith JA, LaPointe N, Morfini G, Brady S, Feinstein S, Wilson L, Jordan MA. Abstract C213: Eribulin, vincristine, ixabepilone, and paclitaxel inhibit neuronal cell function by varied mechanisms and to varying degrees. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C213  0.544
2011 Brady S. The curious case of the soluble protein Developmental Cell. 20: 581-582. DOI: 10.1016/J.Devcel.2011.05.003  0.561
2010 Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nature Neuroscience. 13: 1396-403. PMID 20953194 DOI: 10.1038/Nn.2660  0.744
2010 Brady S, Morfini G. A perspective on neuronal cell death signaling and neurodegeneration Molecular Neurobiology. 42: 25-31. PMID 20480262 DOI: 10.1007/S12035-010-8128-2  0.374
2010 Han I, You Y, Kordower JH, Brady ST, Morfini GA. Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features. Journal of Neurochemistry. 113: 1073-91. PMID 20236390 DOI: 10.1111/J.1471-4159.2010.06672.X  0.36
2010 Hu YS, Xu P, Pigino G, Brady ST, Larson J, Lazarov O. Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1667-81. PMID 20086049 DOI: 10.1096/Fj.09-136945  0.381
2010 Kins S, Hunzelmann S, Szodorai A, Kuan Y, Engel U, Müller U, Beyreuther K, Brady S, Morfini G. Assembly of APP anterograde transport vesicles Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.316  0.405
2009 Szodorai A, Kuan YH, Hunzelmann S, Engel U, Sakane A, Sasaki T, Takai Y, Kirsch J, Müller U, Beyreuther K, Brady S, Morfini G, Kins S. APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14534-44. PMID 19923287 DOI: 10.1523/Jneurosci.1546-09.2009  0.429
2009 Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, ... ... Brady ST, et al. Axonal transport defects in neurodegenerative diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12776-86. PMID 19828789 DOI: 10.1523/Jneurosci.3463-09.2009  0.83
2009 Morfini GA, You YM, Pollema SL, Kaminska A, Liu K, Yoshioka K, Björkblom B, Coffey ET, Bagnato C, Han D, Huang CF, Banker G, Pigino G, Brady ST. Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nature Neuroscience. 12: 864-71. PMID 19525941 DOI: 10.1038/Nn.2346  0.581
2009 Pigino G, Morfini G, Atagi Y, Deshpande A, Yu C, Jungbauer L, LaDu M, Busciglio J, Brady S. Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta. Proceedings of the National Academy of Sciences of the United States of America. 106: 5907-12. PMID 19321417 DOI: 10.1073/Pnas.0901229106  0.819
2009 LaPointe NE, Morfini G, Pigino G, Gaisina IN, Kozikowski AP, Binder LI, Brady ST. The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. Journal of Neuroscience Research. 87: 440-51. PMID 18798283 DOI: 10.1002/Jnr.21850  0.506
2008 Gould RM, Oakley T, Goldstone JV, Dugas JC, Brady ST, Gow A. Myelin sheaths are formed with proteins that originated in vertebrate lineages. Neuron Glia Biology. 4: 137-52. PMID 19737434 DOI: 10.1017/S1740925X09990238  0.448
2008 DeBoer SR, You Y, Szodorai A, Kaminska A, Pigino G, Nwabuisi E, Wang B, Estrada-Hernandez T, Kins S, Brady ST, Morfini G. Conventional kinesin holoenzymes are composed of heavy and light chain homodimers. Biochemistry. 47: 4535-43. PMID 18361505 DOI: 10.1021/Bi702445J  0.492
2008 Solowska JM, Morfini G, Falnikar A, Himes BT, Brady ST, Huang D, Baas PW. Quantitative and functional analyses of spastin in the nervous system: implications for hereditary spastic paraplegia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2147-57. PMID 18305248 DOI: 10.1523/Jneurosci.3159-07.2008  0.431
2008 Szebenyi G, Morfini G, Young M, Sheridan S, McPhaul MJ, Brady ST. Proteins with pathogenic polyglutamine expansion inhibit fast axonal transport Journal of Neurochemistry. 81: 76-76. DOI: 10.1046/J.1471-4159.81.S1.44_4.X  0.521
2008 Stokely ME, Brady ST, Yorio T. Endothelin-B receptor mediates effect of intravitreal endothelin on mitochondria-associated anterograde axonal transport Journal of Neurochemistry. 81: 93-94. DOI: 10.1046/J.1471-4159.81.S1.34_7.X  0.46
2008 Morfini G, Szebenyi G, Brown H, Wray R, Reyna H, Brady ST. Identification of a novel pathway for the in vivo regulation of fast anterograde axonal transport Journal of Neurochemistry. 81: 93-94. DOI: 10.1046/j.1471-4159.81.s1.34_6.x  0.518
2007 Morfini G, Pigino G, Brady ST. Approaches to kinesin-1 phosphorylation. Methods in Molecular Biology (Clifton, N.J.). 392: 51-69. PMID 17951710 DOI: 10.1007/978-1-59745-490-2_4  0.441
2007 Lazarov O, Morfini GA, Pigino G, Gadadhar A, Chen X, Robinson J, Ho H, Brady ST, Sisodia SS. Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7011-20. PMID 17596450 DOI: 10.1523/Jneurosci.4272-06.2007  0.518
2007 Serulle Y, Morfini G, Pigino G, Moreira JE, Sugimori M, Brady ST, Llinás RR. 1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCdelta enzymatic activities. Proceedings of the National Academy of Sciences of the United States of America. 104: 2437-41. PMID 17287339 DOI: 10.1073/Pnas.0611227104  0.316
2007 Morfini G, Pigino G, Opalach K, Serulle Y, Moreira JE, Sugimori M, Llinás RR, Brady ST. 1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 104: 2442-7. PMID 17287338 DOI: 10.1073/Pnas.0611231104  0.486
2007 Morfini G, Pigino G, Mizuno N, Kikkawa M, Brady ST. Tau binding to microtubules does not directly affect microtubule-based vesicle motility. Journal of Neuroscience Research. 85: 2620-30. PMID 17265463 DOI: 10.1002/Jnr.21154  0.49
2006 Morfini G, Pigino G, Szebenyi G, You Y, Pollema S, Brady ST. JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport. Nature Neuroscience. 9: 907-16. PMID 16751763 DOI: 10.1038/Nn1717  0.523
2005 Szebenyi G, Bollati F, Bisbal M, Sheridan S, Faas L, Wray R, Haferkamp S, Nguyen S, Caceres A, Brady ST. Activity-driven dendritic remodeling requires microtubule-associated protein 1A. Current Biology : Cb. 15: 1820-6. PMID 16243028 DOI: 10.1016/J.Cub.2005.08.069  0.373
2005 Lazarov O, Morfini GA, Lee EB, Farah MH, Szodorai A, DeBoer SR, Koliatsos VE, Kins S, Lee VM, Wong PC, Price DL, Brady ST, Sisodia SS. Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2386-95. PMID 15745965 DOI: 10.1523/Jneurosci.3089-04.2005  0.511
2005 Morfini G, Pigino G, Brady ST. Polyglutamine expansion diseases: failing to deliver. Trends in Molecular Medicine. 11: 64-70. PMID 15694868 DOI: 10.1016/J.Molmed.2004.12.002  0.443
2005 Francis F, Roy S, Brady ST, Black MM. Transport of neurofilaments in growing axons requires microtubules but not actin filaments. Journal of Neuroscience Research. 79: 442-50. PMID 15635594 DOI: 10.1002/Jnr.20399  0.715
2005 Gould RM, Brady ST. Dialogues: Communication Between Axons and Myelinating Glia Multiple Sclerosis as a Neuronal Disease. 29-44. DOI: 10.1016/B978-012738761-1/50003-1  0.409
2004 Busciglio J, Brady S, Takashima A, Klein P, Kim L, LaFerla F, Geula C, Stokely M, Tezapsidis N, Gouras G, Strobel G, Crutcher K, Forero D. Axonal transport hypothesis moves on to implicate presenilin: Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 537-545. PMID 15573458 DOI: 10.3233/Jad-2004-6511  0.57
2004 Liu HH, Brady ST. cAMP, tubulin, axonal transport, and regeneration. Experimental Neurology. 189: 199-203. PMID 15380472 DOI: 10.1016/J.Expneurol.2004.06.006  0.536
2004 Morfini G, Szebenyi G, Brown H, Pant HC, Pigino G, DeBoer S, Beffert U, Brady ST. A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. The Embo Journal. 23: 2235-45. PMID 15152189 DOI: 10.1038/Sj.Emboj.7600237  0.629
2004 Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J. Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1897-906. PMID 14985430 DOI: 10.1523/Jneurosci.4084-03.2004  0.335
2003 Szebenyi G, Morfini GA, Babcock A, Gould M, Selkoe K, Stenoien DL, Young M, Faber PW, MacDonald ME, McPhaul MJ, Brady ST. Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport. Neuron. 40: 41-52. PMID 14527432 DOI: 10.1016/S0896-6273(03)00569-5  0.609
2003 Pigino G, Morfini G, Pelsman A, Mattson MP, Brady ST, Busciglio J. Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4499-508. PMID 12805290 DOI: 10.1523/Jneurosci.23-11-04499.2003  0.599
2002 Morfini G, Pigino G, Beffert U, Busciglio J, Brady ST. Fast axonal transport misregulation and Alzheimer's disease. Neuromolecular Medicine. 2: 89-99. PMID 12428805 DOI: 10.1385/Nmm:2:2:089  0.503
2002 Stokely ME, Brady ST, Yorio T. Effects of endothelin-1 on components of anterograde axonal transport in optic nerve. Investigative Ophthalmology & Visual Science. 43: 3223-30. PMID 12356828  0.461
2002 Szebenyi G, Morfini G, Brady ST. Pictures in cell biology. GSK-3 and regulation of kinesin function. Trends in Cell Biology. 12: 245. PMID 12062174 DOI: 10.1016/S0962-8924(02)02283-3  0.423
2002 Szebenyi G, Smith GM, Li P, Brady ST. Overexpression of neurofilament H disrupts normal cell structure and function. Journal of Neuroscience Research. 68: 185-98. PMID 11948664 DOI: 10.1002/Jnr.10212  0.333
2002 Morfini G, Szebenyi G, Elluru R, Ratner N, Brady ST. Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. The Embo Journal. 21: 281-93. PMID 11823421 DOI: 10.1093/Emboj/21.3.281  0.566
2001 Morfini G, Szebenyi G, Richards B, Brady ST. Regulation of kinesin: implications for neuronal development. Developmental Neuroscience. 23: 364-76. PMID 11756752 DOI: 10.1159/000048720  0.522
2001 Kirkpatrick LL, Witt AS, Payne HR, Shine HD, Brady ST. Changes in microtubule stability and density in myelin-deficient shiverer mouse CNS axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2288-97. PMID 11264304 DOI: 10.1523/Jneurosci.21-07-02288.2001  0.586
2000 Roy S, Coffee P, Smith G, Liem RK, Brady ST, Black MM. Neurofilaments are transported rapidly but intermittently in axons: implications for slow axonal transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6849-61. PMID 10995829  0.707
2000 Li JY, Pfister KK, Brady ST, Dahlström A. Cytoplasmic dynein conversion at a crush injury in rat peripheral axons. Journal of Neuroscience Research. 61: 151-61. PMID 10878588 DOI: 10.1002/1097-4547(20000715)61:2<151::Aid-Jnr6>3.0.Co;2-N  0.599
2000 Tsai MY, Morfini G, Szebenyi G, Brady ST. Release of kinesin from vesicles by hsc70 and regulation of fast axonal transport. Molecular Biology of the Cell. 11: 2161-73. PMID 10848636 DOI: 10.1091/Mbc.11.6.2161  0.451
2000 Brady ST. Neurofilaments run sprints not marathons. Nature Cell Biology. 2: E43-5. PMID 10707096 DOI: 10.1038/35004071  0.54
2000 Witt A, Brady ST. Unwrapping new layers of complexity in axon/glial relationships. Glia. 29: 112-7. PMID 10625328 DOI: 10.1002/(Sici)1098-1136(20000115)29:2<112::Aid-Glia3>3.0.Co;2-Z  0.478
2000 Roy S, Coffee P, Smith G, Liem RKH, Brady ST, Black MM. Neurofilaments Are Transported Rapidly But Intermittently in Axons: Implications for Slow Axonal Transport The Journal of Neuroscience. 20: 6849-6861. DOI: 10.1523/Jneurosci.20-18-06849.2000  0.739
1999 Li JY, Pfister KK, Brady S, Dahlström A. Axonal transport and distribution of immunologically distinct kinesin heavy chains in rat neurons. Journal of Neuroscience Research. 58: 226-41. PMID 10502279 DOI: 10.1002/(Sici)1097-4547(19991015)58:2<226::Aid-Jnr3>3.0.Co;2-X  0.507
1999 Brady ST, Witt AS, Kirkpatrick LL, de Waegh SM, Readhead C, Tu PH, Lee VM. Formation of compact myelin is required for maturation of the axonal cytoskeleton. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7278-88. PMID 10460234 DOI: 10.1523/Jneurosci.19-17-07278.1999  0.549
1999 Huang JD, Brady ST, Richards BW, Stenolen D, Resau JH, Copeland NG, Jenkins NA. Direct interaction of microtubule- and actin-based transport motors. Nature. 397: 267-70. PMID 9930703 DOI: 10.1038/16722  0.445
1998 Ratner N, Bloom GS, Brady ST. A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7717-26. PMID 9742142 DOI: 10.1523/Jneurosci.18-19-07717.1998  0.564
1997 Stenoien DL, Brady ST. Immunochemical analysis of kinesin light chain function. Molecular Biology of the Cell. 8: 675-89. PMID 9247647 DOI: 10.1091/Mbc.8.4.675  0.451
1996 Sickles DW, Brady ST, Testino A, Friedman MA, Wrenn RW. Direct effect of the neurotoxicant acrylamide on kinesin-based microtubule motility. Journal of Neuroscience Research. 46: 7-17. PMID 8892100 DOI: 10.1002/(Sici)1097-4547(19961001)46:1<7::Aid-Jnr2>3.0.Co;2-P  0.557
1995 Brady ST. A kinesin medley: biochemical and functional heterogeneity. Trends in Cell Biology. 5: 159-64. PMID 14732151 DOI: 10.1016/S0962-8924(00)88980-1  0.319
1995 Brady ST, Sperry AO. Biochemical and functional diversity of microtubule motors in the nervous system. Current Opinion in Neurobiology. 5: 551-8. PMID 8580705 DOI: 10.1016/0959-4388(95)80058-1  0.325
1995 Elluru RG, Bloom GS, Brady ST. Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms. Molecular Biology of the Cell. 6: 21-40. PMID 7538359 DOI: 10.1091/Mbc.6.1.21  0.584
1995 Cyr JL, Sperry AO, Brady ST. The Kinesin Superfamily: Variations on a Theme Advances in Molecular and Cell Biology. 12: 165-190. DOI: 10.1016/S1569-2558(08)60263-5  0.359
1994 Mercer JA, Albanesi JP, Brady ST. Molecular motors and cell motility in the brain. Brain Pathology (Zurich, Switzerland). 4: 167-79. PMID 8061861  0.453
1994 Kirkpatrick LL, Brady ST. Modulation of the axonal microtubule cytoskeleton by myelinating Schwann cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7440-50. PMID 7996186 DOI: 10.1523/Jneurosci.14-12-07440.1994  0.615
1994 Brady ST. Molecular motors and fast axonal transport Proceedings - Annual Meeting, Microscopy Society of America. 22-23.  0.484
1993 Brady ST. Motor neurons and neurofilaments in sickness and in health. Cell. 73: 1-3. PMID 8462093 DOI: 10.1016/0092-8674(93)90151-F  0.313
1993 Bloom GS, Richards BW, Leopold PL, Ritchey DM, Brady ST. GTP gamma S inhibits organelle transport along axonal microtubules. The Journal of Cell Biology. 120: 467-76. PMID 7678421 DOI: 10.1083/Jcb.120.2.467  0.575
1993 Brady ST, Richards BW, Leopold PL. Assay of vesicle motility in squid axoplasm. Methods in Cell Biology. 39: 191-202. PMID 7504159 DOI: 10.1016/S0091-679X(08)60171-5  0.463
1992 Leopold PL, McDowall AW, Pfister KK, Bloom GS, Brady ST. Association of kinesin with characterized membrane-bounded organelles. Cell Motility and the Cytoskeleton. 23: 19-33. PMID 1382871 DOI: 10.1002/Cm.970230104  0.345
1992 de Waegh SM, Lee VM, Brady ST. Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell. 68: 451-63. PMID 1371237 DOI: 10.1016/0092-8674(92)90183-D  0.6
1992 Cyr JL, Brady ST. Molecular motors in axonal transport. Cellular and molecular biology of kinesin. Molecular Neurobiology. 6: 137-55. PMID 1282328 DOI: 10.1007/Bf02780549  0.615
1991 Wagner MC, Pfister KK, Brady ST, Bloom GS. Purification of kinesin from bovine brain and assay of microtubule-stimulated ATPase activity. Methods in Enzymology. 196: 157-75. PMID 1851939 DOI: 10.1016/0076-6879(91)96016-K  0.409
1991 Brady ST. Molecular motors in the nervous system. Neuron. 7: 521-33. PMID 1834098 DOI: 10.1016/0896-6273(91)90365-7  0.617
1991 Brady ST, Pfister KK. Kinesin interactions with membrane bounded organelles in vivo and in vitro. Journal of Cell Science. Supplement. 14: 103-8. PMID 1832161 DOI: 10.1242/Jcs.1991.Supplement_14.21  0.309
1991 de Waegh SM, Brady ST. Local control of axonal properties by Schwann cells: neurofilaments and axonal transport in homologous and heterologous nerve grafts. Journal of Neuroscience Research. 30: 201-12. PMID 1795404 DOI: 10.1002/Jnr.490300121  0.573
1991 Stein SA, McIntire DD, Kirkpatrick LL, Adams PM, Brady ST. Hypothyroidism selectively reduces the rate and amount of transport for specific SCb proteins in the hyt/hyt mouse optic nerve. Journal of Neuroscience Research. 30: 28-41. PMID 1724471 DOI: 10.1002/Jnr.490300105  0.541
1991 Dahlström AB, Pfister KK, Brady ST. The axonal transport motor 'kinesin' is bound to anterogradely transported organelles: quantitative cytofluorimetric studies of fast axonal transport in the rat. Acta Physiologica Scandinavica. 141: 469-76. PMID 1715108 DOI: 10.1111/j.1748-1716.1991.tb09107.x  0.516
1991 Hirokawa N, Sato-Yoshitake R, Kobayashi N, Pfister KK, Bloom GS, Brady ST. Kinesin associates with anterogradely transported membranous organelles in vivo. The Journal of Cell Biology. 114: 295-302. PMID 1712789 DOI: 10.1083/Jcb.114.2.295  0.49
1991 Stein SA, Kirkpatrick LL, Shanklin DR, Adams PM, Brady ST. Hypothyroidism reduces the rate of slow component A (SCa) axonal transport and the amount of transported tubulin in the hyt/hyt mouse optic nerve. Journal of Neuroscience Research. 28: 121-33. PMID 1710281 DOI: 10.1002/Jnr.490280113  0.547
1991 Brady S, Black M, Soifer D. Preface Journal of Neuroscience Research. 30: v-vi.  0.335
1990 de Waegh S, Brady ST. Altered slow axonal transport and regeneration in a myelin-deficient mutant mouse: the trembler as an in vivo model for Schwann cell-axon interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1855-65. PMID 2355253 DOI: 10.1523/Jneurosci.10-06-01855.1990  0.567
1990 Leopold PL, Snyder R, Bloom GS, Brady ST. Nucleotide specificity for the bidirectional transport of membrane-bounded organelles in isolated axoplasm. Cell Motility and the Cytoskeleton. 15: 210-9. PMID 1692515 DOI: 10.1002/Cm.970150404  0.573
1990 Brady ST, Pfister KK, Bloom GS. A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proceedings of the National Academy of Sciences of the United States of America. 87: 1061-5. PMID 1689058 DOI: 10.1073/Pnas.87.3.1061  0.535
1989 Llinás R, Sugimori M, Lin JW, Leopold PL, Brady ST. ATP-dependent directional movement of rat synaptic vesicles injected into the presynaptic terminal of squid giant synapse. Proceedings of the National Academy of Sciences of the United States of America. 86: 5656-60. PMID 2748609 DOI: 10.1073/Pnas.86.14.5656  0.332
1989 Wagner MC, Pfister KK, Bloom GS, Brady ST. Copurification of kinesin polypeptides with microtubule-stimulated Mg-ATPase activity and kinetic analysis of enzymatic properties. Cell Motility and the Cytoskeleton. 12: 195-215. PMID 2524282 DOI: 10.1002/Cm.970120403  0.373
1989 Pfister KK, Wagner MC, Stenoien DL, Brady ST, Bloom GS. Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. The Journal of Cell Biology. 108: 1453-63. PMID 2522455 DOI: 10.1083/Jcb.108.4.1453  0.352
1989 Hirokawa N, Pfister KK, Yorifuji H, Wagner MC, Brady ST, Bloom GS. Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell. 56: 867-78. PMID 2522351 DOI: 10.1016/0092-8674(89)90691-0  0.327
1989 McGuinness TL, Brady ST, Gruner JA, Sugimori M, Llinas R, Greengard P. Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 4138-49. PMID 2512374  0.355
1989 Pfister KK, Wagner MC, Bloom GS, Brady ST. Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport. Biochemistry. 28: 9006-12. PMID 2481499 DOI: 10.1021/Bi00449A008  0.526
1989 McQuarrie IG, Brady ST, Lasek RJ. Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging. Neurobiology of Aging. 10: 359-65. PMID 2478905 DOI: 10.1016/0197-4580(89)90049-3  0.749
1989 de Waegh S, Brady ST. Axonal transport of a clathrin uncoating ATPase (HSC70): a role for HSC70 in the modulation of coated vesicle assembly in vivo. Journal of Neuroscience Research. 23: 433-40. PMID 2475643 DOI: 10.1002/Jnr.490230409  0.61
1989 McGuinness T, Brady S, Gruner J, Sugimori M, Llinas R, Greengard P. Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm The Journal of Neuroscience. 9: 4138-4149. DOI: 10.1523/Jneurosci.09-12-04138.1989  0.46
1988 Cancalon P, Brady ST, Lasek RJ. Slow transport in a nerve with embryonic characteristics, the olfactory nerve. Brain Research. 466: 275-85. PMID 2452001 DOI: 10.1016/0165-3806(88)90053-3  0.66
1987 Sahenk Z, Brady ST, Mendell JR. Studies on the pathogenesis of vincristine-induced neuropathy. Muscle & Nerve. 10: 80-4. PMID 3031498 DOI: 10.1002/Mus.880100115  0.59
1987 Sahenk Z, Brady ST. Axonal tubulin and microtubules: morphologic evidence for stable regions on axonal microtubules. Cell Motility and the Cytoskeleton. 8: 155-64. PMID 2891447 DOI: 10.1002/Cm.970080207  0.53
1987 Johnston KM, Brady ST, van der Kooy D, Connolly JA. A unique tubulin antibody which disrupts particle movement in squid axoplasm. Cell Motility and the Cytoskeleton. 7: 110-5. PMID 2438055 DOI: 10.1002/Cm.970070203  0.421
1987 Oblinger MM, Brady ST, McQuarrie IG, Lasek RJ. Cytotypic differences in the protein composition of the axonally transported cytoskeleton in mammalian neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 453-62. PMID 2434629 DOI: 10.1523/Jneurosci.07-02-00453.1987  0.849
1986 Brady ST, Black MM. Axonal transport of microtubule proteins: cytotypic variation of tubulin and MAPs in neurons. Annals of the New York Academy of Sciences. 466: 199-217. PMID 2425679 DOI: 10.1111/J.1749-6632.1986.Tb38395.X  0.71
1986 McQuarrie IG, Brady ST, Lasek RJ. Diversity in the axonal transport of structural proteins: major differences between optic and spinal axons in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1593-605. PMID 2423662 DOI: 10.1523/Jneurosci.06-06-01593.1986  0.757
1985 Lasek RJ, Brady ST. Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP. Nature. 316: 645-7. PMID 4033761 DOI: 10.1038/316645A0  0.665
1985 Schroer TA, Brady ST, Kelly RB. Fast axonal transport of foreign synaptic vesicles in squid axoplasm. The Journal of Cell Biology. 101: 568-72. PMID 3848436 DOI: 10.1083/Jcb.101.2.568  0.371
1985 Brady ST, Lasek RJ, Allen RD. Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms. Cell Motility. 5: 81-101. PMID 2580632  0.711
1985 Fahim MA, Lasek RJ, Brady ST, Hodge AJ. AVEC-DIC and electron microscopic analyses of axonally transported particles in cold-blocked squid giant axons. Journal of Neurocytology. 14: 689-704. PMID 2419517 DOI: 10.1007/Bf01170822  0.632
1985 Brady ST. A novel brain ATPase with properties expected for the fast axonal transport motor. Nature. 317: 73-5. PMID 2412134 DOI: 10.1038/317073A0  0.608
1984 Martz D, Lasek RJ, Brady ST, Allen RD. Mitochondrial motility in axons: membranous organelles may interact with the force generating system through multiple surface binding sites. Cell Motility. 4: 89-101. PMID 6733777  0.626
1984 Brady ST, Tytell M, Lasek RJ. Axonal tubulin and axonal microtubules: biochemical evidence for cold stability. The Journal of Cell Biology. 99: 1716-24. PMID 6490717 DOI: 10.1083/Jcb.99.5.1716  0.825
1984 Lasek RJ, Garner JA, Brady ST. Axonal transport of the cytoplasmic matrix. The Journal of Cell Biology. 99: 212s-221s. PMID 6378920 DOI: 10.1083/Jcb.99.1.212S  0.841
1984 Brady ST, Lasek RJ, Allen RD, Yin HL, Stossel TP. Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments. Nature. 310: 56-8. PMID 6204208 DOI: 10.1038/310056A0  0.722
1984 Tytell M, Brady ST, Lasek RJ. Axonal transport of a subclass of tau proteins: evidence for the regional differentiation of microtubules in neurons. Proceedings of the National Academy of Sciences of the United States of America. 81: 1570-4. PMID 6200879 DOI: 10.1073/Pnas.81.5.1570  0.832
1984 Tytell M, Brady ST, Lasek RJ. Axonal transport of a subclass of τ proteins: Evidence for the regional differentiation of microtubules in neurons Isotopenpraxis. 20: 1570-1574.  0.825
1982 Brady ST, Lasek RJ, Allen RD. Fast axonal transport in extruded axoplasm from squid giant axon. Science (New York, N.Y.). 218: 1129-31. PMID 6183745 DOI: 10.1126/Science.6183745  0.742
1982 Allen RD, Metuzals J, Tasaki I, Brady ST, Gilbert SP. Fast axonal transport in squid giant axon. Science (New York, N.Y.). 218: 1127-9. PMID 6183744 DOI: 10.1126/Science.6183744  0.458
1982 Brady ST, Lasek RJ. Axonal transport: a cell-biological method for studying proteins that associate with the cytoskeleton. Methods in Cell Biology. 25: 365-98. PMID 6180280 DOI: 10.1016/S0091-679X(08)61434-X  0.756
1982 Lasek RJ, Brady ST. The axon: a prototype for studying expressional cytoplasm. Cold Spring Harbor Symposia On Quantitative Biology. 46: 113-24. PMID 6179689  0.729
1981 Brady ST, Tytell M, Heriot K, Lasek RJ. Axonal transport of calmodulin: a physiologic approach to identification of long-term associations between proteins. The Journal of Cell Biology. 89: 607-14. PMID 6166619 DOI: 10.1083/Jcb.89.3.607  0.799
1981 Brady ST, Lasek RJ. Nerve-specific enolase and creatine phosphokinase in axonal transport: soluble proteins and the axoplasmic matrix. Cell. 23: 515-23. PMID 6162572 DOI: 10.1016/0092-8674(81)90147-1  0.733
1980 Brady ST, Tytell M, Heriot K, Lasek RJ. Calmodulin in axonal transport. Annals of the New York Academy of Sciences. 356: 361-2. PMID 6165310 DOI: 10.1111/J.1749-6632.1980.Tb29627.X  0.824
1980 Brady ST, Crothers SD, Nosal C, McClure WO. Fast axonal transport in the presence of high Ca2+: evidence that microtubules are not required. Proceedings of the National Academy of Sciences of the United States of America. 77: 5909-13. PMID 6160585 DOI: 10.1073/Pnas.77.10.5909  0.724
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