G. William Rebeck - Publications

Georgetown University, Washington, DC 
Molecular mechanisms of Alzheimer's disease

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Malik M, Parikh I, Vasquez JB, Smith C, Tai L, Bu G, LaDu MJ, Fardo DW, Rebeck GW, Estus S. Genetics ignite focus on microglial inflammation in Alzheimer's disease. Molecular Neurodegeneration. 10: 52. PMID 26438529 DOI: 10.1186/s13024-015-0048-1  1
2015 Zhou Y, Zhao W, Al-Muhtasib N, Rebeck GW. APOE genotype alters immunoglobulin subtypes in knock-in mice Journal of Alzheimer's Disease. 46: 365-374. DOI: 10.3233/JAD-142184  1
2014 Burrell TC, Divekar SD, Weeber EJ, Rebeck GW. Fyn tyrosine kinase increases Apolipoprotein E Receptor 2 levels and phosphorylation. Plos One. 9: e110845. PMID 25340851 DOI: 10.1371/journal.pone.0110845  1
2014 DiBattista AM, Stevens BW, Rebeck GW, Green AE. Two Alzheimer's disease risk genes increase entorhinal cortex volume in young adults. Frontiers in Human Neuroscience. 8: 779. PMID 25339884 DOI: 10.3389/fnhum.2014.00779  1
2014 Rodriguez GA, Tai LM, LaDu MJ, Rebeck GW. Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition. Journal of Neuroinflammation. 11: 111. PMID 24948358 DOI: 10.1186/1742-2094-11-111  1
2014 Trotter JH, Lussier AL, Psilos KE, Mahoney HL, Sponaugle AE, Hoe HS, Rebeck GW, Weeber EJ. Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation. Neuroscience. 274: 299-307. PMID 24892761 DOI: 10.1016/j.neuroscience.2014.05.046  1
2014 Divekar SD, Burrell TC, Lee JE, Weeber EJ, Rebeck GW. Ligand-induced homotypic and heterotypic clustering of apolipoprotein E receptor 2. The Journal of Biological Chemistry. 289: 15894-903. PMID 24755222 DOI: 10.1074/jbc.M113.537548  1
2014 Tai LM, Mehra S, Shete V, Estus S, Rebeck GW, Bu G, LaDu MJ. Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk. Molecular Neurodegeneration. 9: 2. PMID 24386905 DOI: 10.1186/1750-1326-9-2  1
2014 Tamboli IY, Heo D, Rebeck GW. Extracellular proteolysis of apolipoprotein e (apoE) by secreted serine neuronal protease Plos One. 9. DOI: 10.1371/journal.pone.0093120  1
2013 Rodriguez GA, Burns MP, Weeber EJ, Rebeck GW. Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. Learning & Memory (Cold Spring Harbor, N.Y.). 20: 256-66. PMID 23592036 DOI: 10.1101/lm.030031.112  1
2013 Rogers JT, Zhao L, Trotter JH, Rusiana I, Peters MM, Li Q, Donaldson E, Banko JL, Keenoy KE, Rebeck GW, Hoe HS, D'Arcangelo G, Weeber EJ. Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse. Journal of Psychopharmacology (Oxford, England). 27: 386-95. PMID 23104248 DOI: 10.1177/0269881112463468  1
2013 Dumanis SB, DiBattista AM, Miessau M, Moussa CE, Rebeck GW. APOE genotype affects the pre-synaptic compartment of glutamatergic nerve terminals. Journal of Neurochemistry. 124: 4-14. PMID 22862561 DOI: 10.1111/j.1471-4159.2012.07908.x  1
2013 Manaye KF, Mouton PR, Xu G, Drew A, Lei DL, Sharma Y, Rebeck GW, Turner S. Age-related loss of noradrenergic neurons in the brains of triple transgenic mice Age. 35: 139-147. PMID 22127507 DOI: 10.1007/s11357-011-9343-0  1
2012 Youmans KL, Tai LM, Nwabuisi-Heath E, Jungbauer L, Kanekiyo T, Gan M, Kim J, Eimer WA, Estus S, Rebeck GW, Weeber EJ, Bu G, Yu C, Ladu MJ. APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease. The Journal of Biological Chemistry. 287: 41774-86. PMID 23060451 DOI: 10.1074/jbc.M112.407957  1
2012 Dumanis SB, Chamberlain KA, Jin Sohn Y, Jin Lee Y, Guénette SY, Suzuki T, Mathews PM, Pak DTs, Rebeck GW, Suh YH, Park HS, Hoe HS. FE65 as a link between VLDLR and APP to regulate their trafficking and processing. Molecular Neurodegeneration. 7: 9. PMID 22429478 DOI: 10.1186/1750-1326-7-9  1
2012 Herman AM, Khandelwal PJ, Rebeck GW, Moussa CE. Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models. Experimental Neurology. 235: 297-305. PMID 22402344 DOI: 10.1016/j.expneurol.2012.02.011  1
2012 Zhu Y, Nwabuisi-Heath E, Dumanis SB, Tai LM, Yu C, Rebeck GW, LaDu MJ. APOE genotype alters glial activation and loss of synaptic markers in mice. Glia. 60: 559-69. PMID 22228589 DOI: 10.1002/glia.22289  1
2012 Khandelwal PJ, Dumanis SB, Herman AM, Rebeck GW, Moussa CE. Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models. Molecular and Cellular Neurosciences. 49: 44-53. PMID 21945393 DOI: 10.1016/j.mcn.2011.09.002  1
2012 Minami SS, Clifford TG, Hoe HS, Matsuoka Y, Rebeck GW. Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice. Neurobiology of Aging. 33: 825.e15-24. PMID 21741124 DOI: 10.1016/j.neurobiolaging.2011.05.014  1
2011 Babus LW, Little EM, Keenoy KE, Minami SS, Chen E, Song JM, Caviness J, Koo SY, Pak DT, Rebeck GW, Turner RS, Hoe HS. Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice. Brain Research. 1415: 96-102. PMID 21872217 DOI: 10.1016/j.brainres.2011.07.059  1
2011 Rogers JT, Rusiana I, Trotter J, Zhao L, Donaldson E, Pak DT, Babus LW, Peters M, Banko JL, Chavis P, Rebeck GW, Hoe HS, Weeber EJ. Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 558-64. PMID 21852430 DOI: 10.1101/lm.2153511  1
2011 Minami SS, Hoe HS, Rebeck GW. Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes Journal of Neurochemistry. 118: 879-890. PMID 21534960 DOI: 10.1111/j.1471-4159.2011.07296.x  1
2011 Khandelwal PJ, Herman AM, Hoe HS, Rebeck GW, Moussa CE. Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models. Human Molecular Genetics. 20: 2091-102. PMID 21378096 DOI: 10.1093/hmg/ddr091  1
2011 Herman AM, Khandelwal PJ, Stanczyk BB, Rebeck GW, Moussa CE. β-amyloid triggers ALS-associated TDP-43 pathology in AD models. Brain Research. 1386: 191-9. PMID 21376022 DOI: 10.1016/j.brainres.2011.02.052  1
2011 Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP. Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury. Journal of Neurotrauma. 28: 225-36. PMID 21175399 DOI: 10.1089/neu.2010.1595  1
2010 Khandelwal PJ, Dumanis SB, Feng LR, Maguire-Zeiss K, Rebeck G, Lashuel HA, Moussa CE. Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model. Molecular Neurodegeneration. 5: 47. PMID 21050448 DOI: 10.1186/1750-1326-5-47  1
2010 Minami SS, Sidahmed E, Aid S, Shimoji M, Niikura T, Mocchetti I, Rebeck GW, Prendergast JS, Dealwis C, Wetzel R, Bosetti F, Matsuoka Y, Hoe HS, Turner RS. Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease. Journal of Neuroinflammation. 7: 57. PMID 20920207 DOI: 10.1186/1742-2094-7-57  1
2010 Minami SS, Cordova A, Cirrito JR, Tesoriero JA, Babus LW, Davis GC, Dakshanamurthy S, Turner RS, Pak DTs, Rebeck GW, Paige M, Hoe HS. ApoE mimetic peptide decreases Abeta production in vitro and in vivo. Molecular Neurodegeneration. 5: 16. PMID 20406479 DOI: 10.1186/1750-1326-5-16  1
2010 Burns MP, Rebeck GW. Intracellular cholesterol homeostasis and amyloid precursor protein processing. Biochimica Et Biophysica Acta. 1801: 853-9. PMID 20304094 DOI: 10.1016/j.bbalip.2010.03.004  1
2010 Rebeck GW, Hoe HS, Moussa CEH. β-Amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss Journal of Biological Chemistry. 285: 7440-7446. PMID 20071340 DOI: 10.1074/jbc.M109.083915  1
2010 Cartagena CM, Burns MP, Rebeck GW. 24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury. Brain Research. 1319: 1-12. PMID 20053345 DOI: 10.1016/j.brainres.2009.12.080  1
2010 Minami SS, Sung YM, Dumanis SB, Chi SH, Burns MP, Ann EJ, Suzuki T, Turner RS, Park HS, Pak DT, Rebeck GW, Hoe HS. The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 58-69. PMID 19720620 DOI: 10.1096/fj.09-138123  1
2009 Dumanis SB, Tesoriero JA, Babus LW, Nguyen MT, Trotter JH, Ladu MJ, Weeber EJ, Turner RS, Xu B, Rebeck GW, Hoe HS. ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15317-22. PMID 19955384 DOI: 10.1523/JNEUROSCI.4026-09.2009  1
2009 Pocivavsek A, Rebeck GW. Inhibition of c-Jun N-terminal kinase increases apoE expression in vitro and in vivo. Biochemical and Biophysical Research Communications. 387: 516-20. PMID 19615334 DOI: 10.1016/j.bbrc.2009.07.048  1
2009 Pocivavsek A, Mikhailenko I, Strickland DK, Rebeck GW. Microglial low-density lipoprotein receptor-related protein 1 modulates c-Jun N-terminal kinase activation. Journal of Neuroimmunology. 214: 25-32. PMID 19586665 DOI: 10.1016/j.jneuroim.2009.06.010  1
2009 Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW. Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7459-73. PMID 19515914 DOI: 10.1523/JNEUROSCI.4872-08.2009  1
2009 Burns MP, Zhang L, Rebeck GW, Querfurth HW, Moussa CE. Parkin promotes intracellular Abeta1-42 clearance. Human Molecular Genetics. 18: 3206-16. PMID 19483198 DOI: 10.1093/hmg/ddp258  1
2009 Rebeck GW. Nontraditional signaling mechanisms of lipoprotein receptors Science Signaling. 2: pe28. PMID 19401589 DOI: 10.1126/scisignal.268pe28  1
2009 Loane DJ, Pocivavsek A, Moussa CE, Thompson R, Matsuoka Y, Faden AI, Rebeck GW, Burns MP. Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nature Medicine. 15: 377-9. PMID 19287391 DOI: 10.1038/nm.1940  1
2009 Hoe HS, Fu Z, Makarova A, Lee JY, Lu C, Feng L, Pajoohesh-Ganji A, Matsuoka Y, Hyman BT, Ehlers MD, Vicini S, Pak DT, Rebeck GW. The effects of amyloid precursor protein on postsynaptic composition and activity. The Journal of Biological Chemistry. 284: 8495-506. PMID 19164281 DOI: 10.1074/jbc.M900141200  1
2009 Hirata-Fukae C, Li HF, Ma L, Hoe HS, Rebeck GW, Aisen PS, Matsuoka Y. Levels of soluble and insoluble tau reflect overall status of tau phosphorylation in vivo Neuroscience Letters. 450: 51-55. PMID 19022346 DOI: 10.1016/j.neulet.2008.11.023  1
2009 Pocivavsek A, Burns MP, Rebeck GW. Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase. Glia. 57: 444-53. PMID 18803301 DOI: 10.1002/glia.20772  1
2008 Zhao X, Rebeck GW, Hoe HS, Andrews PM. Tarenflurbil protection from cytotoxicity is associated with an upregulation of neurotrophins Journal of Alzheimer's Disease. 15: 397-407. PMID 18997293  1
2008 Cartagena CM, Ahmed F, Burns MP, Pajoohesh-Ganji A, Pak DT, Faden AI, Rebeck GW. Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain. Journal of Neurotrauma. 25: 1087-98. PMID 18729719 DOI: 10.1089/neu.2007.0444  1
2008 Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, et al. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Research. 1216: 92-103. PMID 18486110 DOI: 10.1016/j.brainres.2008.03.079  1
2008 Hoe HS, Rebeck GW. Regulated proteolysis of APP and ApoE receptors Molecular Neurobiology. 37: 64-72. PMID 18415033 DOI: 10.1007/s12035-008-8017-0  1
2008 Hoe HS, Minami SS, Makarova A, Lee J, Hyman BT, Matsuoka Y, Rebeck GW. Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing. The Journal of Biological Chemistry. 283: 6288-99. PMID 18089558 DOI: 10.1074/jbc.M704140200  1
2007 Hoe HS, Cooper MJ, Burns MP, Lewis PA, van der Brug M, Chakraborty G, Cartagena CM, Pak DT, Cookson MR, Rebeck GW. The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10895-905. PMID 17913923 DOI: 10.1523/JNEUROSCI.3135-07.2007  1
2007 Eckert GP, Vardanian L, Rebeck GW, Burns MP. Regulation of central nervous system cholesterol homeostasis by the liver X receptor agonist TO-901317. Neuroscience Letters. 423: 47-52. PMID 17662526 DOI: 10.1016/j.neulet.2007.05.063  1
2007 Czech C, Burns MP, Vardanian L, Augustin A, Jacobsen H, Baumann K, Rebeck GW. Cholesterol independent effect of LXR agonist TO-901317 on gamma-secretase. Journal of Neurochemistry. 101: 929-36. PMID 17472585 DOI: 10.1111/j.1471-4159.2007.04467.x  1
2006 Rebeck GW, LaDu MJ, Estus S, Bu G, Weeber EJ. The generation and function of soluble apoE receptors in the CNS. Molecular Neurodegeneration. 1: 15. PMID 17062143 DOI: 10.1186/1750-1326-1-15  1
2006 Hoe HS, Tran TS, Matsuoka Y, Howell BW, Rebeck GW. DAB1 and reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing Journal of Biological Chemistry. 281: 35176-35185. PMID 16951405 DOI: 10.1074/jbc.M602162200  1
2006 Hoe HS, Pocivavsek A, Dai H, Chakraborty G, Harris DC, Rebeck GW. Effects of apoE on neuronal signaling and APP processing in rodent brain. Brain Research. 1112: 70-9. PMID 16905123 DOI: 10.1016/j.brainres.2006.07.035  1
2006 Burns MP, Vardanian L, Pajoohesh-Ganji A, Wang L, Cooper M, Harris DC, Duff K, Rebeck GW. The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo. Journal of Neurochemistry. 98: 792-800. PMID 16771834 DOI: 10.1111/j.1471-4159.2006.03925.x  1
2006 Hoe HS, Magill LA, Guenette S, Fu Z, Vicini S, Rebeck GW. FE65 interaction with the ApoE receptor ApoEr2. The Journal of Biological Chemistry. 281: 24521-30. PMID 16638748 DOI: 10.1074/jbc.M600728200  0.36
2006 Robbins EM, Betensky RA, Domnitz SB, Purcell SM, Garcia-Alloza M, Greenberg C, Rebeck GW, Hyman BT, Greenberg SM, Frosch MP, Bacskai BJ. Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 365-71. PMID 16407531 DOI: 10.1523/JNEUROSCI.3854-05.2006  1
2006 Hoe HS, Pocivavsek A, Chakraborty G, Fu Z, Vicini S, Ehlers MD, Rebeck GW. Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor. The Journal of Biological Chemistry. 281: 3425-31. PMID 16332682 DOI: 10.1074/jbc.M509380200  1
2006 Hoe HS, Freeman J, Rebeck GW. Apolipoprotein e decreases tau kinases and phospho-tau levels in primary neurons Molecular Neurodegeneration. 1. DOI: 10.1186/1750-1326-1-18  1
2005 Hoe HS, Wessner D, Beffert U, Becker AG, Matsuoka Y, Rebeck GW. F-spondin interaction with the apolipoprotein E receptor ApoEr2 affects processing of amyloid precursor protein. Molecular and Cellular Biology. 25: 9259-68. PMID 16227578 DOI: 10.1128/MCB.25.21.9259-9268.2005  1
2005 Domnitz SB, Robbins EM, Hoang AW, Garcia-Alloza M, Hyman BT, Rebeck GW, Greenberg SM, Bacskai BJ, Frosch MP. Progression of cerebral amyloid angiopathy in transgenic mouse models of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 64: 588-94. PMID 16042310  1
2005 Hoe HS, Rebeck GW. Regulation of ApoE receptor proteolysis by ligand binding Molecular Brain Research. 137: 31-39. PMID 15950758 DOI: 10.1016/j.molbrainres.2005.02.013  1
2005 Martin-Rehrmann MD, Hoe HS, Capuani EM, Rebeck GW. Association of apolipoprotein J-positive β-amyloid plaques with dystrophic neurites in alzheimer's disease brain Neurotoxicity Research. 7: 231-241. PMID 15897157 DOI: 10.1007/BF03036452  1
2005 Hoe HS, Harris DC, Rebeck GW. Multiple pathways of apolipoprotein E signaling in primary neurons Journal of Neurochemistry. 93: 145-155. PMID 15773914 DOI: 10.1111/j.1471-4159.2004.03007.x  1
2004 Ingelsson M, Jesneck J, Irizarry MC, Hyman BT, Rebeck GW. Lack of association of the cholesterol 24-hydroxylase (CYP46) intron 2 polymorphism with Alzheimer's disease. Neuroscience Letters. 367: 228-31. PMID 15331159 DOI: 10.1016/j.neulet.2004.06.011  1
2004 Irizarry MC, Deng A, Lleo A, Berezovska O, Von Arnim CA, Martin-Rehrmann M, Manelli A, LaDu MJ, Hyman BT, Rebeck GW. Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein. Journal of Neurochemistry. 90: 1132-43. PMID 15312168 DOI: 10.1111/j.1471-4159.2004.02581.x  1
2004 Rebeck GW. Cholesterol efflux as a critical component of Alzheimer's disease pathogenesis. Journal of Molecular Neuroscience : Mn. 23: 219-224. PMID 15181250  1
2004 Qiu Z, Hyman BT, Rebeck GW. Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons. The Journal of Biological Chemistry. 279: 34948-56. PMID 15169786 DOI: 10.1074/jbc.M401055200  1
2004 Eng JA, Frosch MP, Choi K, Rebeck GW, Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Annals of Neurology. 55: 250-6. PMID 14755729 DOI: 10.1002/ana.10810  1
2003 Qiu Z, Crutcher KA, Hyman BT, Rebeck GW. ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes. Neuroscience. 122: 291-303. PMID 14614897 DOI: 10.1016/j.neuroscience.2003.08.017  1
2003 Wang X, Lee SR, Arai K, Tsuji K, Rebeck GW, Lo EH. Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator Nature Medicine. 9: 1313-1317. PMID 12960961 DOI: 10.1038/nm926  1
2003 Fukumoto H, Ingelsson M, GÃ¥revik N, Wahlund LO, Nukina N, Yaguchi Y, Shibata M, Hyman BT, Rebeck GW, Irizarry MC. APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis. Experimental Neurology. 183: 249-53. PMID 12957508 DOI: 10.1016/S0014-4886(03)00088-8  1
2003 Greenberg SM, Shin Y, Grabowski TJ, Cooper GE, Rebeck GW, Iglesias S, Chapon F, Tournier-Lasserve E, Baron JC. Hemorrhagic stroke associated with the Iowa amyloid precursor protein mutation. Neurology. 60: 1020-2. PMID 12654973  1
2003 Shin Y, Cho HS, Fukumoto H, Shimizu T, Shirasawa T, Greenberg SM, Rebeck GW. Aβ species, including IsoAsp23 Aβ, in Iowa-type familial cerebral amyloid angiopathy Acta Neuropathologica. 105: 252-258. PMID 12557012  1
2002 Shin Y, Cho HS, Rebeck GW, Greenberg SM. Vascular changes in Iowa-type hereditary cerebral amyloid angiopathy Annals of the New York Academy of Sciences. 977: 245-251. PMID 12480757  1
2002 Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW. Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Aβ levels Journal of Biological Chemistry. 277: 48508-48513. PMID 12384498 DOI: 10.1074/jbc.M209085200  1
2002 Guénette SY, Chang Y, Hyman BT, Tanzi RE, Rebeck GW. Low-density lipoprotein receptor-related protein levels and endocytic function are reduced by overexpression of the FE65 adaptor protein, FE65L1. Journal of Neurochemistry. 82: 755-62. PMID 12358780 DOI: 10.1046/j.1471-4159.2002.01009.x  1
2002 Rebeck GW, Kindy M, LaDu MJ. Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3. Journal of Alzheimer's Disease : Jad. 4: 145-54. PMID 12226533  1
2002 Martin-Rehrmann MD, Hyun SC, Rebeck GW. Lack of association of two lipoprotein lipase polymorphisms with Alzheimer's disease Neuroscience Letters. 328: 109-112. PMID 12133567 DOI: 10.1016/S0304-3940(02)00511-6  1
2002 Arélin K, Kinoshita A, Whelan CM, Irizarry MC, Rebeck GW, Strickland DK, Hyman BT. LRP and senile plaques in Alzheimer's disease: colocalization with apolipoprotein E and with activated astrocytes. Brain Research. Molecular Brain Research. 104: 38-46. PMID 12117549 DOI: 10.1016/S0169-328X(02)00203-6  1
2001 Rebeck GW, Cho HS, Grabowski TJ, Greenberg SM. The effects of AbetaPP mutations and APOE polymorphisms on cerebral amyloid angiopathy. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 8: 43-7. PMID 11676289  1
2001 Deng A, Irizarry MC, Nitsch RM, Growdon JH, Rebeck GW. Elevation of cystatin C in susceptible neurons in Alzheimer's disease. The American Journal of Pathology. 159: 1061-8. PMID 11549598 DOI: 10.1016/S0002-9440(10)61781-6  1
2001 Van Nostrand WE, Melchor JP, Cho HS, Greenberg SM, Rebeck GW. Pathogenic Effects of D23N Iowa Mutant Amyloid β-Protein Journal of Biological Chemistry. 276: 32860-32866. PMID 11441013 DOI: 10.1074/jbc.M104135200  1
2001 Qiu Z, Naten DL, Liston JC, Yess J, Rebeck GW. A novel approach for studying endogenous Aβ processing using cultured primary neurons isolated from APP transgenic mice Experimental Neurology. 170: 186-194. PMID 11421596 DOI: 10.1006/exnr.2001.7703  1
2001 Berezovska O, Jack C, Deng A, Gastineau N, Rebeck GW, Hyman BT. Notch1 and Amyloid Precursor Protein Are Competitive Substrates for Presenilin1-dependent γ-Secretase Cleavage Journal of Biological Chemistry. 276: 30018-30023. PMID 11408475 DOI: 10.1074/jbc.M008268200  1
2001 Qiu Z, Strickland DK, Hyman BT, Rebeck GW. Elevation of LDL receptor-related protein levels via ligand interactions in alzheimer disease and in vitro Journal of Neuropathology and Experimental Neurology. 60: 430-440. PMID 11379818 DOI: 10.1093/jnen/60.5.430  1
2001 Cho HS, Hyman BT, Greenberg SM, Rebeck GW. Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Aβ aggregation Journal of Neuropathology and Experimental Neurology. 60: 342-349. PMID 11305869  1
2001 Rebeck GW, Moir RD, Mui S, Strickland DK, Tanzi RE, Hyman BT. Association of membrane-bound amyloid precursor protein APP with the apolipoprotein E receptor LRP. Brain Research. Molecular Brain Research. 87: 238-45. PMID 11245926 DOI: 10.1016/S0169-328X(01)00006-7  1
2000 Irizarry MC, Rebeck GW, Cheung B, Bales K, Paul SM, Holzman D, Hyman BT. Modulation of Aβ deposition in APP transgenic mice by an apolipoprotein E null background Annals of the New York Academy of Sciences. 920: 171-178. PMID 11193147  1
2000 Guénette SY, Bertram L, Crystal A, Bakondi B, Hyman BT, Rebeck GW, Tanzi RE, Blacker D. Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients. Neuroscience Letters. 296: 17-20. PMID 11099823 DOI: 10.1016/S0304-3940(00)01607-4  1
2000 Finckh U, von der Kammer H, Velden J, Michel T, Andresen B, Deng A, Zhang J, Müller-Thomsen T, Zuchowski K, Menzer G, Mann U, Papassotiropoulos A, Heun R, Zurdel J, Holst F, ... ... Rebeck GW, et al. Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Archives of Neurology. 57: 1579-83. PMID 11074789  1
2000 Rebeck GW. Confirmation of the genetic association of interleukin-1A with early onset sporadic Alzheimer's disease Neuroscience Letters. 293: 75-77. PMID 11065142 DOI: 10.1016/S0304-3940(00)01487-7  1
2000 Irizarry MC, Cheung BS, Rebeck GW, Paul SM, Bales KR, Hyman BT. Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid β-peptide deposition in homozygous APP(V717F) transgenic mice Acta Neuropathologica. 100: 451-458. PMID 11045665 DOI: 10.1007/s004010000263  1
2000 Bacskai BJ, Xia MQ, Strickland DK, Rebeck GW, Hyman BT. The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 11551-6. PMID 11016955 DOI: 10.1073/pnas.200238297  1
2000 Hyman BT, Strickland D, Rebeck GW. Role of the low-density lipoprotein receptor-related protein in β- amyloid metabolism and Alzheimer disease Archives of Neurology. 57: 646-650. PMID 10815129  1
2000 Ulery PG, Beers J, Mikhailenko I, Tanzi RE, Rebeck GW, Hyman BT, Strickland DK. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease. The Journal of Biological Chemistry. 275: 7410-5. PMID 10702315 DOI: 10.1074/jbc.275.10.7410  1
1999 Growdon WB, Cheung BS, Hyman BT, Rebeck GW. Lack of allelic imbalance in APOE ε3/4 brain mRNA expression in Alzheimer's disease Neuroscience Letters. 272: 83-86. PMID 10507547 DOI: 10.1016/S0304-3940(99)00557-1  1
1999 Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J, Greenberg SM, Hyman BT. Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease Neuroscience Letters. 272: 155-158. PMID 10505604 DOI: 10.1016/S0304-3940(99)00602-3  1
1999 Qiu Z, Strickland DK, Hyman BT, Rebeck GW. α2-Macroglobulin enhances the clearance of endogenous soluble β- amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons Journal of Neurochemistry. 73: 1393-1398. PMID 10501182 DOI: 10.1046/j.1471-4159.1999.0731393.x  1
1999 Rebeck GW. Cutting in a lipid bilayer? Trends in Genetics. 15: 258-259. PMID 10475854 DOI: 10.1016/S0168-9525(99)01765-5  1
1999 Lai F, Kammann E, Rebeck GW, Anderson A, Chen Y, Nixon RA. APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome. Neurology. 53: 331-6. PMID 10430422  1
1999 Clatworthy AE, Stockinger W, Christie RH, Schneider WJ, Nimpf J, Hyman BT, Rebeck GW. Expression and alternate splicing of apolipoprotein E receptor 2 in brain. Neuroscience. 90: 903-11. PMID 10218790 DOI: 10.1016/S0306-4522(98)00489-8  1
1998 Liao A, Nitsch RM, Greenberg SM, Finckh U, Blacker D, Albert M, Rebeck GW, Gomez-Isla T, Clatworthy A, Binetti G, Hock C, Mueller-Thomsen T, Mann U, Zuchowski K, Beisiegel U, et al. Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. Human Molecular Genetics. 7: 1953-6. PMID 9811940 DOI: 10.1093/hmg/7.12.1953  1
1998 Hollenbach E, Ackermann S, Hyman BT, Rebeck GW. Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease Neurology. 50: 1905-1907. PMID 9633759  1
1998 Alonzo NC, Hyman BT, Rebeck GW, Greenberg SM. Progression of cerebral amyloid angiopathy: Accumulation of amyloid- β40 in affected vessels Journal of Neuropathology and Experimental Neurology. 57: 353-359. PMID 9600229  1
1998 Greenberg SM, Vonsattel JPG, Segal AZ, Chiu RI, Clatworthy AE, Liao A, Hyman BT, Rebeck GW. Association of apolipoprotein E and ε2 vasculopathy in cerebral amyloid angiopathy Neurology. 50: 961-965. PMID 9566379 DOI: 10.1212/WNL.50.4.961  1
1998 Rebeck GW, Alonzo NC, Berezovska O, Harr SD, Knowles RB, Growdon JH, Hyman BT, Mendez AJ. Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes. Experimental Neurology. 149: 175-82. PMID 9454626 DOI: 10.1006/exnr.1997.6710  1
1997 Clatworthy AE, Gomez-Isla T, Rebeck GW, Wallace RB, Hyman BT. Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease Archives of Neurology. 54: 1289-1292. PMID 9341576 DOI: 10.1001/archneur.1997.00550220087019  1
1996 Hyman BT, Gomez-Isla T, Rebeck GW, Briggs M, Chung H, West HL, Greenberg S, Mui S, Nichols S, Wallace R, Growdon JH. Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 1-5. PMID 8993478 DOI: 10.1111/j.1749-6632.1996.tb32592.x  1
1996 Mui S, Briggs M, Chung H, Wallace RB, Gomez-Isla T, Rebeck GW, Hyman BT. A newly identified polymorphism in the apolipoprotein E enhancer gene region is associated with Alzheimer's disease and strongly with the ε4 allele Neurology. 47: 196-201. PMID 8710077 DOI: 10.1212/WNL.47.1.196  1
1996 Hyman BT, Hedley-Whyte ET, Rebeck GW, Vonsattel JP, West HL, Growdon JH. Apolipoprotein E epsilon4/4 in a neuropathologically normal very elderly individual. Archives of Neurology. 53: 215. PMID 8651872  1
1996 Chung H, Roberts CT, Greenberg S, Rebeck GW, Christie R, Wallace R, Jacob HJ, Hyman BT. Lack of association of trinucleotide repeat polymorphisms in very-low-density lipoprotein receptor gene with Alzheimer's disease. Annals of Neurology. 39: 800-3. PMID 8651653 DOI: 10.1002/ana.410390617  1
1996 Hyman BT, Gomez-Isla T, West H, Briggs M, Chung H, Growdon JH, Rebeck GW. Clinical and neuropathological correlates of apolipoprotein E genotype in Alzheimer's disease. Window on molecular epidemiology. Annals of the New York Academy of Sciences. 777: 158-65. PMID 8624079  1
1996 Gomez-Isla T, West HL, Rebeck GW, Harr SD, Growdon JH, Locascio JJ, Perls TT, Lipsitz LA, Hyman BT. Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease. Annals of Neurology. 39: 62-70. PMID 8572669 DOI: 10.1002/ana.410390110  1
1995 Rebeck GW, Hyman BT. Apolipoprotein e--correction Neurology. 45: 598. PMID 7898732  1
1995 Hyman BT, West HL, Rebeck GW, Buldyrev SV, Mantegna RN, Ukleja M, Havlin S, Stanley HE. Quantitative analysis of senile plaques in Alzheimer disease: Observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome) Proceedings of the National Academy of Sciences of the United States of America. 92: 3586-3590. PMID 7724603 DOI: 10.1073/PNAS.92.8.3586  1
1995 Nitsch RM, Rebeck GW, Deng M, Richardson UI, Tennis M, Schenk DB, Vigo-Pelfrey C, Lieberburg I, Wurtman RJ, Hyman BT. Cerebrospinal fluid levels of amyloid beta-protein in Alzheimer's disease: inverse correlation with severity of dementia and effect of apolipoprotein E genotype. Annals of Neurology. 37: 512-8. PMID 7717688 DOI: 10.1002/ana.410370414  1
1995 Hyman BT, West HL, Rebeck GW, Lai F, Mann DM. Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype. Archives of Neurology. 52: 373-8. PMID 7710373 DOI: 10.1001/archneur.1995.00540280059019  1
1995 Mui S, Rebeck GW, McKenna-Yasek D, Hyman BT, Brown RH. Apolipoprotein E ε4 allele is not associated with earlier age at onset in amyotrophic lateral sclerosis Annals of Neurology. 38: 460-463. PMID 7668834 DOI: 10.1002/ana.410380318  1
1995 Greenberg SM, Rebeck GW, Vonsattel JPG, Gomez-Isla T, Hyman BT. Apolipoprotein E ε4 and cerebral hemorrhage associated with amyloid angiopathy Annals of Neurology. 38: 254-259. PMID 7654074 DOI: 10.1002/ana.410380219  1
1995 Kounnas MZ, Moir RD, Rebeck GW, Bush AI, Argraves WS, Tanzi RE, Hyman BT, Strickland DK. LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell. 82: 331-40. PMID 7543026 DOI: 10.1016/0092-8674(95)90320-8  1
1995 Rebeck GW, Harr SD, Strickland DK, Hyman BT. Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein e receptor, the α2-macroglobulin receptor/low-density-lipoprotein receptor-related protein Annals of Neurology. 37: 211-217. PMID 7531418 DOI: 10.1002/ana.410370212  1
1995 Gearing M, Schneider JA, Rebeck GW, Hyman BT, Mirra SS. Alzheimer's disease with and without coexisting Parkinson's disease changes: apolipoprotein E genotype and neuropathologic correlates. Neurology. 45: 1985-90. PMID 7501146  1
1994 Poduri A, Gearing M, Rebeck GW, Mirra SS, Tigges J, Hyman BT. Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys. The American Journal of Pathology. 144: 1183-7. PMID 8203459  1
1994 Rebeck GW, Maynard KI, Hyman BT, Moskowitz MA. Selective 5-HT1D alpha serotonin receptor gene expression in trigeminal ganglia: implications for antimigraine drug development. Proceedings of the National Academy of Sciences of the United States of America. 91: 3666-9. PMID 8170966  1
1994 Rebeck GW, Perls TT, West HL, Sodhi P, Lipsitz LA, Hyman BT. Reduced apolipoprotein ϵ4 allele frequency in the oldest old alzheimer’s patients and cognitively normal individuals Neurology. 44: 1513-1516. PMID 8058160  1
1994 Hyman BT, Strickland DK, Rebeck GW. α2-Macroglobulin receptor/low density lipoprotein receptor-related protein. Relationship to apolipoprotein E and role in Alzheimer disease senile plaques Annals of the New York Academy of Sciences. 737: 88-95. PMID 7944156 DOI: 10.1111/j.1749-6632.1994.tb44303.x  1
1994 Simonian NA, Rebeck GW, Hyman BT. Functional integrity of neural systems related to memory in Alzheimer's disease Progress in Brain Research. 100: 245-254. PMID 7938525  1
1993 Rebeck GW, Hyman BT. Neuroanatomical connections and specific regional vulnerability in Alzheimer's disease Neurobiology of Aging. 14: 45-47. PMID 8450931 DOI: 10.1016/0197-4580(93)90019-8  1
1993 Rebeck GW, Marzloff K, Hyman BT. The pattern of NADPH-diaphorase staining, a marker of nitric oxide synthase activity, is altered in the perforant pathway terminal zone in Alzheimer's disease Neuroscience Letters. 152: 165-168. PMID 7685863 DOI: 10.1016/0304-3940(93)90509-J  1
1991 Rebeck GW, Samson L. Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase Journal of Bacteriology. 173: 2068-2076. PMID 2002008  1
1989 Rebeck GW, Smith CM, Goad DL, Samson L. Characterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium Journal of Bacteriology. 171: 4563-4568. PMID 2670886  1
1988 Rebeck GW, Coons S, Caroll P, Samson L. A second DNA methyltransferase repair enzyme in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 85: 3039-3043. PMID 3283737  1
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