Kenneth Y. Kwan, Ph.D. - Publications

Neuroscience University of Michigan, Ann Arbor, Ann Arbor, MI 
Cortical development, neural circuit assembly, neurodevelopmental disorders

24/73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Keil JM, Doyle DZ, Qalieh A, Lam MM, Funk OH, Qalieh Y, Shi L, Mohan N, Sorel A, Kwan KY. Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nature Communications. 11: 3839. PMID 32737294 DOI: 10.1038/s41467-020-17551-4  1
2020 Bott CJ, McMahon LP, Keil JM, Yap CC, Kwan KY, Winckler B. Nestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32273484 DOI: 10.1523/JNEUROSCI.2471-19.2020  1
2019 Zhou W, Emery SB, Flasch DA, Wang Y, Kwan KY, Kidd JM, Moran JV, Mills RE. Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology. Nucleic Acids Research. PMID 31853540 DOI: 10.1093/nar/gkz1173  1
2019 Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY. Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nature Communications. 10: 2588. PMID 31197172 DOI: 10.1038/s41467-019-10411-w  1
2018 Keil JM, Qalieh A, Kwan KY. Brain transcriptome databases: a user's guide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29437890 DOI: 10.1523/JNEUROSCI.1930-17.2018  1
2017 McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, et al. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356. PMID 28450582 DOI: 10.1126/science.aal1641  1
2017 Akins MR, Berk-Rauch HE, Kwan KY, Mitchell ME, Shepard KA, Korsak LI, Stackpole EE, Warner-Schmidt JL, Sestan N, Cameron HA, Fallon JR. Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains. Human Molecular Genetics. PMID 28082376 DOI: 10.1093/hmg/ddw381  1
2016 Caubit X, Gubellini P, Andrieux J, Roubertoux PL, Metwaly M, Jacq B, Fatmi A, Had-Aissouni L, Kwan KY, Salin P, Carlier M, Liedén A, Rudd E, Shinawi M, Vincent-Delorme C, et al. TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons. Nature Genetics. PMID 27668656 DOI: 10.1038/ng.3681  1
2014 Colvin SM, Kwan KY. Dysregulated nitric oxide signaling as a candidate mechanism of fragile X syndrome and other neuropsychiatric disorders. Frontiers in Genetics. 5: 239. PMID 25101118 DOI: 10.3389/fgene.2014.00239  1
2014 Funk OH, Kwan KY. Nitric oxide signaling in the development and evolution of language and cognitive circuits. Neuroscience Research. 86: 77-87. PMID 24933499 DOI: 10.1016/j.neures.2014.06.001  1
2014 Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Dravis C, Kwan KY, Šestan N, Greenberg ME, Henkemeyer M, Cowan CW. EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding. Proceedings of the National Academy of Sciences of the United States of America. 111: 2188-93. PMID 24453220 DOI: 10.1073/pnas.1324215111  1
2013 Kwan KY. Transcriptional dysregulation of neocortical circuit assembly in ASD. International Review of Neurobiology. 113: 167-205. PMID 24290386 DOI: 10.1016/B978-0-12-418700-9.00006-X  1
2012 Shim S, Kwan KY, Li M, Lefebvre V, Sestan N. Cis-regulatory control of corticospinal system development and evolution. Nature. 486: 74-9. PMID 22678282 DOI: 10.1038/nature11094  1
2012 Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, RaÅ¡in MR, Sousa AM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, et al. Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell. 149: 899-911. PMID 22579290 DOI: 10.1016/j.cell.2012.02.060  1
2012 Kwan KY, Sestan N, Anton ES. Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex. Development (Cambridge, England). 139: 1535-46. PMID 22492350 DOI: 10.1242/dev.069963  1
2011 Barak T, Kwan KY, Louvi A, Demirbilek V, Sayg? S, Tüysüz B, Choi M, Boyac? H, Doerschner K, Zhu Y, Kaymakçalan H, Y?lmaz S, Bak?rc?o?lu M, Ca?layan AO, Oztürk AK, et al. Recessive LAMC3 mutations cause malformations of occipital cortical development. Nature Genetics. 43: 590-4. PMID 21572413 DOI: 10.1038/ng.836  1
2011 Han W, Kwan KY, Shim S, Lam MM, Shin Y, Xu X, Zhu Y, Li M, Sestan N. TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract. Proceedings of the National Academy of Sciences of the United States of America. 108: 3041-6. PMID 21285371 DOI: 10.1073/pnas.1016723108  1
2010 Bilgüvar K, Oztürk AK, Louvi A, Kwan KY, Choi M, Tatli B, Yalnizo?lu D, Tüysüz B, Ca?layan AO, Gökben S, Kaymakçalan H, Barak T, Bakircio?lu M, Yasuno K, Ho W, et al. Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature. 467: 207-10. PMID 20729831 DOI: 10.1038/nature09327  1
2009 Fertuzinhos S, Krsnik Z, Kawasawa YI, Rasin MR, Kwan KY, Chen JG, Judas M, Hayashi M, Sestan N. Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. Cerebral Cortex (New York, N.Y. : 1991). 19: 2196-207. PMID 19234067 DOI: 10.1093/cercor/bhp009  1
2008 Kwan KY, Lam MM, Krsnik Z, Kawasawa YI, Lefebvre V, Sestan N. SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 16021-6. PMID 18840685 DOI: 10.1073/pnas.0806791105  1
2008 Britanova O, de Juan Romero C, Cheung A, Kwan KY, Schwark M, Gyorgy A, Vogel T, Akopov S, Mitkovski M, Agoston D, Sestan N, Molnár Z, Tarabykin V. Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron. 57: 378-92. PMID 18255031 DOI: 10.1016/j.neuron.2007.12.028  1
2007 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nature Neuroscience. 10: 819-27. PMID 17589506 DOI: 10.1038/nn1924  1
2005 Chen JG, Rasin MR, Kwan KY, Sestan N. Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 102: 17792-7. PMID 16314561 DOI: 10.1073/pnas.0509032102  1
2005 Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, et al. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (New York, N.Y.). 310: 317-20. PMID 16224024 DOI: 10.1126/science.1116502  1
Low-probability matches
2020 Yu AX, Xu ML, Yao P, Kwan KK, Liu YX, Duan R, Dong TT, Ko RK, Tsim KW. Corylin, a flavonoid derived from Psoralea Fructus, induces osteoblastic differentiation via estrogen and Wnt/β-catenin signaling pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31965654 DOI: 10.1096/fj.201902319RRR  0.12
2020 Kwan KEL, Tan CH. The humble chest radiograph: an overlooked diagnostic modality in the COVID-19 pandemic. Quantitative Imaging in Medicine and Surgery. 10: 1887-1890. PMID 32879866 DOI: 10.21037/qims-20-771  0.08
1993 Schwend RB, Hambsch KP, Kwan KY, Boyajian RA, Otis SM. Color duplex sonographically guided obliteration of pseudoaneurysm Journal of Ultrasound in Medicine. 12: 609-613. PMID 8246340  0.01
1993 Rizzo JL, Baker LA, Boyajian RA, Gargollo PM, Hambsch KP, Kwan KY, Schwend RB, Torruella AK, Otis SM. Accuracy of B-mode ultrasound vein mapping for vessel size Journal of Vascular Technology. 17: 287-289.  0.01
2020 Lim ZY, Khoo HW, Hui TCH, Kok SSX, Kwan KEL, Young BE, Tan CH, Kaw GJL. Variable computed tomography appearances of COVID-19. Singapore Medical Journal. PMID 32312025 DOI: 10.11622/smedj.2020066  0.04
2019 Huang Y, Kwan KKL, Leung KW, Yao P, Wang H, Dong TT, Tsim KWK. Ginseng extracts modulate mitochondrial bioenergetics of live cardiomyoblasts: a functional comparison of different extraction solvents. Journal of Ginseng Research. 43: 517-526. PMID 31695560 DOI: 10.1016/j.jgr.2018.02.002  0.04
2019 Kwan KKL, Huang Y, Leung KW, Dong TTX, Tsim KWK. Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Modulates Mitochondrial Bioenergetics in Cultured Cardiomyoblasts. Frontiers in Pharmacology. 10: 614. PMID 31316376 DOI: 10.3389/fphar.2019.00614  0.04
2018 Huang Y, Kwan KKL, Leung KW, Wang H, Kong XP, Dong TTX, Tsim KWK. The Extracts and Major Compounds Derived from Astragali Radix Alter Mitochondrial Bioenergetics in Cultured Cardiomyocytes: Comparison of Various Polar Solvents and Compounds. International Journal of Molecular Sciences. 19. PMID 29799462 DOI: 10.3390/ijms19061574  0.04
2016 Kwan KE, Shelat VG, Tan CH. Recurrent pyogenic cholangitis: a review of imaging findings and clinical management. Abdominal Radiology (New York). PMID 27770158 DOI: 10.1007/s00261-016-0953-y  0.04
2004 Kale A, Kwan K, Jaynes C. Epipolar contrained user pushbutton selection in projected interfaces Ieee Computer Society Conference On Computer Vision and Pattern Recognition Workshops. 2004. DOI: 10.1109/CVPR.2004.332  0.04
2001 Chen ZY, Kwan KY, Huang Y. Accumulation and apparent oxidation of cis,trans-18:2 isomers relative to linoleic acid in rats British Journal of Nutrition. 86: 249-255. PMID 11502239  0.04
1998 Chen ZY, Zhang ZS, Kwan KY, Zhu M, Ho WKK, Huang Y. Endothelium-dependent relaxation induced by hawthorn extract in rat mesenteric artery Life Sciences. 63: 1983-1991. PMID 9839542  0.04
1998 Kwan KY, Wang LY, Chan KP, Chen ZY. Inhibitory effect of linoleic acid on chain elongation and desaturation of 18:2 c,t isomers in lactating and neonatal rats Lipids. 33: 409-416. PMID 9590629 DOI: 10.1007/s11745-998-0222-x  0.04
1997 Chen ZY, Kwan KY, Tong KK, Ratnayake WMN, Li HQ, Leung SSF. Breast milk fatty acid composition: A comparative study between Hong Kong and Chongqing Chinese Lipids. 32: 1061-1067. PMID 9358432 DOI: 10.1007/s11745-997-0137-6  0.04
1997 Chen ZY, Sea MM, Kwan KY, Leung YH, Leung PF. Depletion of linoleate induced by weight cycling is independent of extent of calorie restriction American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 272: R43-R50. PMID 9038989  0.04
1997 Chen ZY, Chan PT, Kwan KY, Zhang A. Reassessment of the antioxidant activity of conjugated linoleic acids Jaocs, Journal of the American Oil Chemists' Society. 74: 749-753.  0.04
1993 Kwan KY, Schwend RB, Baker LA, Torruella AK, Hambsch KP, Rizzo JL, Poceta JS, Otis SM. Unusual hemodynamics associated with a common carotid artery occlusion Journal of Vascular Technology. 17: 149-152.  0.01
2020 Wu Q, Xia Y, Dai K, Bai P, Kwan KKL, Guo MSS, Dong TTX, Tsim KWK. Solar light induces the release of acetylcholine from skin keratinocytes affecting melanogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32519787 DOI: 10.1096/fj.202000708R  0.01
2020 Chan WYS, Kwan KEL, Teo LT. A rare case of retroperitoneal and mesenteric lymphangiomatosis. Radiology Case Reports. 15: 11-14. PMID 31762861 DOI: 10.1016/j.radcr.2019.09.039  0.01
2016 Jadali A, Kwan KY. Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea. Biology Open. PMID 27142333 DOI: 10.1242/bio.016758  0.04
2016 Iwase S, Brookes E, Agarwal S, Badeaux AI, Ito H, Vallianatos CN, Tomassy GS, Kasza T, Lin G, Thompson A, Gu L, Kwan KY, Chen C, Sartor MA, Egan B, et al. A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation. Cell Reports. PMID 26804915 DOI: 10.1016/j.celrep.2015.12.091  0.01
2015 Shen J, Scheffer DI, Kwan KY, Corey DP. SHIELD: an integrative gene expression database for inner ear research. Database : the Journal of Biological Databases and Curation. 2015: bav071. PMID 26209310 DOI: 10.1093/database/bav071  0.04
2015 Kwan KY, Shen J, Corey DP. C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells. Stem Cell Reports. 4: 47-60. PMID 25497456 DOI: 10.1016/j.stemcr.2014.11.001  0.04
2015 Anton D, Su KN, Kwan KY. Future Drives of Home Appliances: Elimination of the Electrolytic DC-Link Capacitor in Electrical Drives for Home Appliances Ieee Industrial Electronics Magazine. 9: 11-18. DOI: 10.1109/MIE.2014.2367051  0.01
2015 Chang TP, Kwan KY, Liberman D, Song E, Dao EH, Chung D, Morton I, Festekjian A. Introducing teamwork challenges in simulation using game cards Simulation in Healthcare. 10: 223-226. DOI: 10.1097/SIH.0000000000000089  0.01
2014 Chang TP, Pham PK, Sobolewski B, Doughty CB, Jamal N, Kwan KY, Little K, Brenkert TE, Mathison DJ. Pediatric emergency medicine asynchronous e-learning: a multicenter randomized controlled Solomon four-group study. Academic Emergency Medicine : Official Journal of the Society For Academic Emergency Medicine. 21: 912-9. PMID 25154469 DOI: 10.1111/acem.12434  0.01
2012 Shigetomi E, Tong X, Kwan KY, Corey DP, Khakh BS. TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nature Neuroscience. 15: 70-80. PMID 22158513 DOI: 10.1038/nn.3000  0.04
2012 Kwan KY. Neoplasm, lymphoma Fleisher and Ludwig's 5-Minute Pediatric Emergency Medicine Consult 0.01
2010 Kwan KY, Nager AL. Diagnosing pediatric appendicitis: Usefulness of laboratory markers American Journal of Emergency Medicine. 28: 1009-1015. PMID 20825931 DOI: 10.1016/j.ajem.2009.06.004  0.01
2009 Brierley SM, Hughes PA, Page AJ, Kwan KY, Martin CM, O'Donnell TA, Cooper NJ, Harrington AM, Adam B, Liebregts T, Holtmann G, Corey DP, Rychkov GY, Blackshaw LA. The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli. Gastroenterology. 137: 2084-2095.e3. PMID 19632231 DOI: 10.1053/j.gastro.2009.07.048  0.04
2009 Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL. TRPA1 modulates mechanotransduction in cutaneous sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4808-19. PMID 19369549 DOI: 10.1523/JNEUROSCI.5380-08.2009  0.04
2009 Kwan KY, Corey DP. Burning cold: involvement of TRPA1 in noxious cold sensation. The Journal of General Physiology. 133: 251-6. PMID 19237590 DOI: 10.1085/jgp.200810146  0.04
2009 Karashima Y, Talavera K, Everaerts W, Janssens A, Kwan KY, Vennekens R, Nilius B, Voets T. TRPA1 acts as a cold sensor in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 106: 1273-1278. PMID 19144922 DOI: 10.1073/pnas.0808487106  0.04
2008 Mohanty S, Town T, Yagi T, Scheidig C, Kwan KY, Allore HG, Flavell RA, Shaw AC. Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proceedings of the National Academy of Sciences of the United States of America. 105: 5063-8. PMID 18367668 DOI: 10.1073/pnas.0801235105  0.04
2007 Macpherson LJ, Xiao B, Kwan KY, Petrus MJ, Dubin AE, Hwang S, Cravatt B, Corey DP, Patapoutian A. An ion channel essential for sensing chemical damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11412-5. PMID 17942735 DOI: 10.1523/JNEUROSCI.3600-07.2007  0.04
2007 Kwan KY, Greenwald RJ, Mohanty S, Sharpe AH, Shaw AC, Wang JC. Development of autoimmunity in mice lacking DNA topoisomerase 3β Proceedings of the National Academy of Sciences of the United States of America. 104: 9242-9247. PMID 17517607 DOI: 10.1073/pnas.0703587104  0.04
2007 Vollrath MA, Kwan KY, Corey DP. The micromachinery of mechanotransduction in hair cells. Annual Review of Neuroscience. 30: 339-65. PMID 17428178 DOI: 10.1146/annurev.neuro.29.051605.112917  0.04
2006 Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, Woolf CJ, Corey DP. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron. 50: 277-89. PMID 16630838 DOI: 10.1016/j.neuron.2006.03.042  0.04
2004 Corey DP, García-Añoveros J, Holt JR, Kwan KY, Lin SY, Vollrath MA, Amalfitano A, Cheung EL, Derfler BH, Duggan A, Géléoc GS, Gray PA, Hoffman MP, Rehm HL, Tamasauskas D, et al. TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature. 432: 723-30. PMID 15483558 DOI: 10.1038/nature03066  0.04
2003 Yap LKP, Au SYL, Ang YH, Kwan KY, Ng SC, He CH. Who are the residents of a nursing home in Singapore? Singapore Medical Journal. 44: 65-73. PMID 14503779  0.01
2003 Kwan KY, Moens PB, Wang JC. Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase IIIβ Proceedings of the National Academy of Sciences of the United States of America. 100: 2526-2531. PMID 12591952 DOI: 10.1073/pnas.0437998100  0.04
2002 Kwan KY, Kaler KVIS, Mintchev MP. High-pressure balloon catheter for real-time pressure monitoring in the esophagus Proceedings of the Ieee International Conference On Electronics, Circuits, and Systems. 3: 1211-1214. DOI: 10.1109/ICECS.2002.1046471  0.01
2001 Kwan KY, Wang JC. Mice lacking DNA topoisomerase III/β develop to maturity but show a reduced mean lifespan Proceedings of the National Academy of Sciences of the United States of America. 98: 5717-5721. PMID 11331780 DOI: 10.1073/pnas.101132498  0.04
2001 Kwan K. STORM WATER REGULATORY PERSPECTIVE OVERVIEW OF REGION 4'S STORM WATER ENFORCEMENT PROGRAM Proceedings of the Water Environment Federation. 2001: 528-532. DOI: 10.2175/193864701785019227  0.01
2000 Ho JW, Yuen ST, Chung LP, Kwan KY, Chan TL, Leung SY, Chan AS, Tse Cw, Lam PW, Luk IS. Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients. International Journal of Cancer. Journal International Du Cancer. 89: 356-60. PMID 10956410 DOI: 10.1002/1097-0215(20000720)89:4<356::AID-IJC7>3.0.CO;2-J  0.01
1999 Kling KM, Kirby L, Kwan KY, Kim F, McFadden DW. Interleukin-10 inhibits inducible nitric oxide synthase in an animal model of necrotizing enterocolitis. International Journal of Surgical Investigation. 1: 337-42. PMID 12774458  0.01
1999 Ho JW, Yuen ST, Chung LP, So HC, Kwan KY. The role of sulindac in familial adenomatous polyposis patients with ileal pouch polyposis. The Australian and New Zealand Journal of Surgery. 69: 756-8. PMID 10527361 DOI: 10.1046/J.1440-1622.1999.01685.X  0.01
1999 Chan TL, Yuen ST, Chung LP, Ho JW, Kwan K, Fan YW, Chan AS, Leung SY. Germline hMSH2 and differential somatic mutations in patients with Turcot's syndrome. Genes, Chromosomes & Cancer. 25: 75-81. PMID 10337989 DOI: 10.1002/(SICI)1098-2264(199906)25:2<75::AID-GCC1>3.0.CO;2-1  0.01
1996 Dunn JCY, Whano EE, Kwan KY, Ghana C, McFadden DW, Ashlev SW. Post-translationau regulation of the intestinal sodiumglucose cotransporter along the crypt-villus axis Faseb Journal. 10: A770.  0.01
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