| Year |
Citation |
Score |
| 2024 |
Mishra PS, Phaneuf D, Boutej H, Picher-Martel V, Dupre N, Kriz J, Julien JP. Inhibition of NF-κB with an Analog of Withaferin-A Restores TDP-43 Homeostasis and Proteome Profiles in a Model of Sporadic ALS. Biomedicines. 12. PMID 38790979 DOI: 10.3390/biomedicines12051017 |
0.342 |
|
| 2024 |
Pokrishevsky E, DuVal MG, McAlary L, Louadi S, Pozzi S, Roman A, Plotkin SS, Dijkstra A, Julien JP, Allison WT, Cashman NR. Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1. The Journal of Biological Chemistry. 107207. PMID 38522514 DOI: 10.1016/j.jbc.2024.107207 |
0.337 |
|
| 2023 |
Pelaez MC, Desmeules A, Gelon PA, Glasson B, Marcadet L, Rodgers A, Phaneuf D, Pozzi S, Dutchak PA, Julien JP, Sephton CF. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition. Acta Neuropathologica Communications. 11: 182. PMID 37974279 DOI: 10.1186/s40478-023-01671-1 |
0.398 |
|
| 2023 |
Nath B, Phaneuf D, Julien JP. Axonal Transport Defect in Gigaxonin Deficiency Rescued by Tubastatin A. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 37268847 DOI: 10.1007/s13311-023-01393-1 |
0.397 |
|
| 2023 |
Nath B, Julien JP. A new mouse model of giant axonal neuropathy with overt phenotypes and neurodegeneration driven by neurofilament disorganization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37137704 DOI: 10.1523/JNEUROSCI.1959-22.2023 |
0.396 |
|
| 2020 |
Dutta K, Thammisetty SS, Boutej H, Bareil C, Julien JP. Mitigation of ALS pathology by neuron-specific inhibition of nuclear factor kappa B signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32457070 DOI: 10.1523/Jneurosci.0536-20.2020 |
0.502 |
|
| 2020 |
Gafson AR, Barthélemy NR, Bomont P, Carare RO, Durham HD, Julien JP, Kuhle J, Leppert D, Nixon RA, Weller RO, Zetterberg H, Matthews PM. Neurofilaments: neurobiological foundations for biomarker applications. Brain : a Journal of Neurology. PMID 32408345 DOI: 10.1093/Brain/Awaa098 |
0.301 |
|
| 2020 |
Mishra PS, Boutej H, Soucy G, Bareil C, Kumar S, Picher-Martel V, Dupré N, Kriz J, Julien JP. Transmission of ALS pathogenesis by the cerebrospinal fluid. Acta Neuropathologica Communications. 8: 65. PMID 32381112 DOI: 10.1186/S40478-020-00943-4 |
0.405 |
|
| 2019 |
Renaud L, Picher-Martel V, Codron P, Julien JP. Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia. Acta Neuropathologica Communications. 7: 103. PMID 31319884 DOI: 10.1186/S40478-019-0758-7 |
0.396 |
|
| 2019 |
Pozzi S, Thammisetty SS, Codron P, Rahimian R, Plourde KV, Soucy G, Bareil C, Phaneuf D, Kriz J, Gravel C, Julien JP. Viral-mediated delivery of antibody targeting TAR DNA-binding protein 43 mitigates associated neuropathology. The Journal of Clinical Investigation. PMID 30667370 DOI: 10.1172/Jci123931 |
0.422 |
|
| 2019 |
Picher-Martel V, Renaud L, Julien J. GP.02 Neuronal expression of Ubiqulin-2 mutant exacerbates TDP-43 aggregation in ALS mouse mode Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 46: S6. DOI: 10.1017/cjn.2019.78 |
0.403 |
|
| 2018 |
Walker CL, Uchida A, Li Y, Trivedi N, Fenn JD, Monsma PC, Lariviére RC, Julien JP, Jung P, Brown A. Local acceleration of neurofilament transport at nodes of Ranvier. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30541916 DOI: 10.1523/Jneurosci.2272-18.2018 |
0.675 |
|
| 2018 |
Picher-Martel V, Renaud L, Bareil C, Julien JP. Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin. Molecular Neurobiology. PMID 30377984 DOI: 10.1007/S12035-018-1411-3 |
0.493 |
|
| 2018 |
Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, Julien JP, Gilthorpe JD, Marklund SL, Cashman NR, Andersen PM, Forsberg K, Dupré N, Gould P, Brännström T, Gros-Louis F. Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis. Scientific Reports. 8: 14223. PMID 30242181 DOI: 10.1038/S41598-018-31773-Z |
0.36 |
|
| 2018 |
Dutta K, Patel P, Julien JP. Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis. Experimental Neurology. PMID 30134145 DOI: 10.1016/J.Expneurol.2018.08.008 |
0.427 |
|
| 2018 |
Pozzi S, Thammisetty SS, Julien JP. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 29790082 DOI: 10.1007/S13311-018-0634-3 |
0.42 |
|
| 2017 |
Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, La Fontaine A, Maios C, Liao M, Ciura S, Wen XY, Rafuse V, Ichida J, Zinman L, Julien JP, et al. Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis. Jci Insight. 2. PMID 29202456 DOI: 10.1172/Jci.Insight.97152 |
0.325 |
|
| 2017 |
Komatsu K, Imamura K, Yamashita H, Julien JP, Takahashi R, Inoue H. Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons. Neuroreport. PMID 29140847 DOI: 10.1097/Wnr.0000000000000922 |
0.496 |
|
| 2017 |
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, ... ... Julien JP, et al. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28539470 DOI: 10.1126/Scitranslmed.Aaf3962 |
0.438 |
|
| 2016 |
Dutta K, Patel P, Rahimian R, Phaneuf D, Julien JP. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27928708 DOI: 10.1007/S13311-016-0499-2 |
0.496 |
|
| 2016 |
Iguchi Y, Eid L, Parent M, Soucy G, Bareil C, Riku Y, Kawai K, Takagi S, Yoshida M, Katsuno M, Sobue G, Julien JP. Exosome secretion is a key pathway for clearance of pathological TDP-43. Brain : a Journal of Neurology. PMID 27679482 DOI: 10.1093/Brain/Aww237 |
0.409 |
|
| 2016 |
Ohta Y, Soucy G, Phaneuf D, Audet JN, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, Julien JP. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Human Molecular Genetics. PMID 27580881 DOI: 10.1093/hmg/ddw304 |
0.307 |
|
| 2016 |
Picher-Martel V, Valdmanis PN, Gould PV, Julien JP, Dupré N. From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathologica Communications. 4: 70. PMID 27400686 DOI: 10.1186/S40478-016-0340-5 |
0.392 |
|
| 2016 |
Yadav P, Selvaraj BT, Bender FL, Behringer M, Moradi M, Sivadasan R, Dombert B, Blum R, Asan E, Sauer M, Julien JP, Sendtner M. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathologica. PMID 27021905 DOI: 10.1007/S00401-016-1564-Y |
0.344 |
|
| 2016 |
Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, Julien JP, Goldman RD, Opal P. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in Giant Axonal Neuropathy. Human Molecular Genetics. PMID 27000625 DOI: 10.1093/Hmg/Ddw081 |
0.444 |
|
| 2015 |
MacNair L, Xiao S, Miletic D, Ghani M, Julien JP, Keith J, Zinman L, Rogaeva E, Robertson J. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 26525917 DOI: 10.1093/Brain/Awv308 |
0.426 |
|
| 2015 |
Picher-Martel V, Dutta K, Phaneuf D, Sobue G, Julien JP. Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells. Molecular Brain. 8: 71. PMID 26521126 DOI: 10.1186/S13041-015-0162-6 |
0.427 |
|
| 2015 |
Correia AS, Patel P, Dutta K, Julien JP. Inflammation Induces TDP-43 Mislocalization and Aggregation. Plos One. 10: e0140248. PMID 26444430 DOI: 10.1371/Journal.Pone.0140248 |
0.399 |
|
| 2015 |
Yuan A, Hassinger L, Rao MV, Julien JP, Miller CC, Nixon RA. Dissociation of Axonal Neurofilament Content from Its Transport Rate. Plos One. 10: e0133848. PMID 26208164 DOI: 10.1371/Journal.Pone.0133848 |
0.41 |
|
| 2015 |
Froud KE, Wong AC, Cederholm JM, Klugmann M, Sandow SL, Julien JP, Ryan AF, Housley GD. Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. Nature Communications. 6: 7115. PMID 25965946 DOI: 10.1038/Ncomms8115 |
0.363 |
|
| 2015 |
Arbour D, Tremblay E, Martineau É, Julien JP, Robitaille R. Early and persistent abnormal decoding by glial cells at the neuromuscular junction in an ALS model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 688-706. PMID 25589763 DOI: 10.1523/Jneurosci.1379-14.2015 |
0.428 |
|
| 2015 |
Patel P, Julien JP, Kriz J. Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 217-33. PMID 25404049 DOI: 10.1007/S13311-014-0311-0 |
0.457 |
|
| 2014 |
Roche SL, Sherman DL, Dissanayake K, Soucy G, Desmazieres A, Lamont DJ, Peles E, Julien JP, Wishart TM, Ribchester RR, Brophy PJ, Gillingwater TH. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12904-18. PMID 25232125 DOI: 10.1523/Jneurosci.1725-14.2014 |
0.429 |
|
| 2014 |
Patel P, Kriz J, Gravel M, Soucy G, Bareil C, Gravel C, Julien JP. Adeno-associated virus-mediated delivery of a recombinant single-chain antibody against misfolded superoxide dismutase for treatment of amyotrophic lateral sclerosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 498-510. PMID 24394188 DOI: 10.1038/Mt.2013.239 |
0.377 |
|
| 2013 |
Saxena S, Roselli F, Singh K, Leptien K, Julien JP, Gros-Louis F, Caroni P. Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 80: 80-96. PMID 24094105 DOI: 10.1016/J.Neuron.2013.07.027 |
0.332 |
|
| 2013 |
Pickles S, Destroismaisons L, Peyrard SL, Cadot S, Rouleau GA, Brown RH, Julien JP, Arbour N, Vande Velde C. Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1. Human Molecular Genetics. 22: 3947-59. PMID 23736301 DOI: 10.1093/Hmg/Ddt249 |
0.353 |
|
| 2013 |
Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. The Journal of Clinical Investigation. 123: 1964-75. PMID 23585478 DOI: 10.1172/Jci66387 |
0.345 |
|
| 2013 |
Millecamps S, Julien JP. Axonal transport deficits and neurodegenerative diseases. Nature Reviews. Neuroscience. 14: 161-76. PMID 23361386 DOI: 10.1038/Nrn3380 |
0.364 |
|
| 2012 |
Swarup V, Audet JN, Phaneuf D, Kriz J, Julien JP. Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18186-95. PMID 23238732 DOI: 10.1523/Jneurosci.2267-12.2012 |
0.471 |
|
| 2012 |
Yuan A, Sasaki T, Kumar A, Peterhoff CM, Rao MV, Liem RK, Julien JP, Nixon RA. Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8501-8. PMID 22723690 DOI: 10.1523/Jneurosci.1081-12.2012 |
0.437 |
|
| 2012 |
Audet JN, Gowing G, Paradis R, Soucy G, Julien JP. Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase. Plos One. 7: e34932. PMID 22523565 DOI: 10.1371/Journal.Pone.0034932 |
0.41 |
|
| 2012 |
Brotherton TE, Li Y, Cooper D, Gearing M, Julien JP, Rothstein JD, Boylan K, Glass JD. Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS. Proceedings of the National Academy of Sciences of the United States of America. 109: 5505-10. PMID 22431618 DOI: 10.1073/Pnas.1115009109 |
0.453 |
|
| 2012 |
Audet JN, Soucy G, Julien JP. Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models. Neuroscience. 209: 136-43. PMID 22230045 DOI: 10.1016/j.neuroscience.2011.12.047 |
0.331 |
|
| 2012 |
Gentil BJ, Minotti S, Beange M, Baloh RH, Julien JP, Durham HD. Normal role of the low-molecular-weight neurofilament protein in mitochondrial dynamics and disruption in Charcot-Marie-Tooth disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1194-203. PMID 22155564 DOI: 10.1096/Fj.11-196345 |
0.395 |
|
| 2012 |
Julien J, Swarup V, Dupre N, Kriz J. TDP-43 Drives Nuclear Factor- B Activation in ALS (P03.179) Neurology. 78: P03.179-P03.179. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.179 |
0.463 |
|
| 2011 |
Swarup V, Phaneuf D, Dupré N, Petri S, Strong M, Kriz J, Julien JP. Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways. The Journal of Experimental Medicine. 208: 2429-47. PMID 22084410 DOI: 10.1084/Jem.20111313 |
0.462 |
|
| 2011 |
Vande Velde C, McDonald KK, Boukhedimi Y, McAlonis-Downes M, Lobsiger CS, Bel Hadj S, Zandona A, Julien JP, Shah SB, Cleveland DW. Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. Plos One. 6: e22031. PMID 21779368 DOI: 10.1371/Journal.Pone.0022031 |
0.44 |
|
| 2011 |
Swarup V, Phaneuf D, Bareil C, Robertson J, Rouleau GA, Kriz J, Julien JP. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain : a Journal of Neurology. 134: 2610-26. PMID 21752789 DOI: 10.1093/Brain/Awr159 |
0.38 |
|
| 2011 |
Filali M, Dequen F, Lalonde R, Julien JP. Sensorimotor and cognitive function of a NEFL(P22S) mutant model of Charcot-Marie-Tooth disease type 2E. Behavioural Brain Research. 219: 175-80. PMID 21168446 DOI: 10.1016/J.Bbr.2010.12.022 |
0.384 |
|
| 2011 |
Swarup V, Julien JP. ALS pathogenesis: recent insights from genetics and mouse models. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 363-9. PMID 20728492 DOI: 10.1016/J.Pnpbp.2010.08.006 |
0.475 |
|
| 2011 |
Dequen F, Cairns NJ, Bigio EH, Julien JP. Gigaxonin mutation analysis in patients with NIFID. Neurobiology of Aging. 32: 1528-9. PMID 19782434 DOI: 10.1016/J.Neurobiolaging.2009.08.018 |
0.361 |
|
| 2010 |
Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nature Neuroscience. 13: 1396-403. PMID 20953194 DOI: 10.1038/Nn.2660 |
0.318 |
|
| 2010 |
Takeuchi S, Fujiwara N, Ido A, Oono M, Takeuchi Y, Tateno M, Suzuki K, Takahashi R, Tooyama I, Taniguchi N, Julien JP, Urushitani M. Induction of protective immunity by vaccination with wild-type apo superoxide dismutase 1 in mutant SOD1 transgenic mice. Journal of Neuropathology and Experimental Neurology. 69: 1044-56. PMID 20838241 DOI: 10.1097/Nen.0B013E3181F4A90A |
0.346 |
|
| 2010 |
Ezzi SA, Larivière R, Urushitani M, Julien JP. Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS. Journal of Neurochemistry. 115: 1102-11. PMID 20807312 DOI: 10.1111/J.1471-4159.2010.06979.X |
0.501 |
|
| 2010 |
Audet JN, Gowing G, Julien JP. Wild-type human SOD1 overexpression does not accelerate motor neuron disease in mice expressing murine Sod1 G86R. Neurobiology of Disease. 40: 245-50. PMID 20573565 DOI: 10.1016/J.Nbd.2010.05.031 |
0.454 |
|
| 2010 |
Dequen F, Filali M, Larivière RC, Perrot R, Hisanaga S, Julien JP. Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E. Human Molecular Genetics. 19: 2616-29. PMID 20421365 DOI: 10.1093/Hmg/Ddq149 |
0.435 |
|
| 2010 |
Gros-Louis F, Soucy G, Larivière R, Julien JP. Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS. Journal of Neurochemistry. 113: 1188-99. PMID 20345765 DOI: 10.1111/J.1471-4159.2010.06683.X |
0.327 |
|
| 2010 |
Barclay M, Julien JP, Ryan AF, Housley GD. Type III intermediate filament peripherin inhibits neuritogenesis in type II spiral ganglion neurons in vitro. Neuroscience Letters. 478: 51-5. PMID 20132868 DOI: 10.1016/J.Neulet.2010.01.063 |
0.394 |
|
| 2010 |
Zhao W, Beers DR, Henkel JS, Zhang W, Urushitani M, Julien JP, Appel SH. Extracellular mutant SOD1 induces microglial-mediated motoneuron injury. Glia. 58: 231-43. PMID 19672969 DOI: 10.1002/Glia.20919 |
0.332 |
|
| 2010 |
Perrot R, Julien J, Chul P. Maldistribution of Neurofilaments, Disease Pathogenesis, and Amyotrophic Lateral Sclerosis Us Neurology. 5: 30. DOI: 10.17925/Usn.2010.05.02.30 |
0.454 |
|
| 2010 |
Gros-Louis F, Andersen PM, Rouleau GA, Julien JP. Reply to van Vught et al.: P413L CHGB as risk factor for ALS Proceedings of the National Academy of Sciences of the United States of America. 107: E78. DOI: 10.1073/Pnas.1003411107 |
0.303 |
|
| 2009 |
Gros-Louis F, Andersen PM, Dupre N, Urushitani M, Dion P, Souchon F, D'Amour M, Camu W, Meininger V, Bouchard JP, Rouleau GA, Julien JP. Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 21777-82. PMID 20007371 DOI: 10.1073/Pnas.0902174106 |
0.369 |
|
| 2009 |
Gowing G, Lalancette-Hébert M, Audet JN, Dequen F, Julien JP. Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase. Experimental Neurology. 220: 267-75. PMID 19733170 DOI: 10.1016/J.Expneurol.2009.08.021 |
0.373 |
|
| 2009 |
Perrot R, Julien JP. Real-time imaging reveals defects of fast axonal transport induced by disorganization of intermediate filaments. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3213-25. PMID 19451279 DOI: 10.1096/Fj.09-129585 |
0.468 |
|
| 2009 |
Gros-Louis F, Gowing G, Julien J. Development of immunization approaches to amyotrophic lateral sclerosis Future Neurology. 4: 435-447. DOI: 10.2217/Fnl.09.21 |
0.429 |
|
| 2008 |
Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10234-44. PMID 18842883 DOI: 10.1523/JNEUROSCI.3494-08.2008 |
0.347 |
|
| 2008 |
Barrette B, Hébert MA, Filali M, Lafortune K, Vallières N, Gowing G, Julien JP, Lacroix S. Requirement of myeloid cells for axon regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9363-76. PMID 18799670 DOI: 10.1523/Jneurosci.1447-08.2008 |
0.404 |
|
| 2008 |
Dequen F, Bomont P, Gowing G, Cleveland DW, Julien JP. Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1. Journal of Neurochemistry. 107: 253-64. PMID 18680552 DOI: 10.1111/J.1471-4159.2008.05601.X |
0.439 |
|
| 2008 |
Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA. Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Human Molecular Genetics. 17: 2691-702. PMID 18558633 DOI: 10.1093/Hmg/Ddn171 |
0.483 |
|
| 2008 |
Urushitani M, Ezzi SA, Matsuo A, Tooyama I, Julien JP. The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2476-87. PMID 18337461 DOI: 10.1096/Fj.07-092783 |
0.429 |
|
| 2008 |
Eriksson KS, Zhang S, Lin L, Larivière RC, Julien JP, Mignot E. The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse. Bmc Neuroscience. 9: 26. PMID 18294400 DOI: 10.1186/1471-2202-9-26 |
0.456 |
|
| 2008 |
Millecamps S, Julien JP. [Dysfunction of axonal transport in neuropathies and motor neuron diseases]. Mã©Decine Sciences : M/S. 24: 65-71. PMID 18198113 DOI: 10.1051/Medsci/200824165 |
0.461 |
|
| 2007 |
Julien JP, Kriz J. Chapter 6 Animal models of motor neuron death. Handbook of Clinical Neurology. 82: 121-38. PMID 18808891 DOI: 10.1016/S0072-9752(07)80009-1 |
0.498 |
|
| 2007 |
Barclay M, Noakes PG, Ryan AF, Julien JP, Housley GD. Neuronal expression of peripherin, a type III intermediate filament protein, in the mouse hindbrain. Histochemistry and Cell Biology. 128: 541-50. PMID 17899157 DOI: 10.1007/S00418-007-0340-4 |
0.417 |
|
| 2007 |
Zhai J, Lin H, Julien JP, Schlaepfer WW. Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1. Human Molecular Genetics. 16: 3103-16. PMID 17881652 DOI: 10.1093/Hmg/Ddm272 |
0.452 |
|
| 2007 |
Millecamps S, Gowing G, Corti O, Mallet J, Julien JP. Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4947-56. PMID 17475803 DOI: 10.1523/Jneurosci.5299-06.2007 |
0.388 |
|
| 2007 |
Julien JP. ALS: astrocytes move in as deadly neighbors. Nature Neuroscience. 10: 535-7. PMID 17453052 DOI: 10.1038/Nn0507-535 |
0.437 |
|
| 2007 |
Barry DM, Millecamps S, Julien JP, Garcia ML. New movements in neurofilament transport, turnover and disease. Experimental Cell Research. 313: 2110-20. PMID 17451679 DOI: 10.1016/J.Yexcr.2007.03.011 |
0.326 |
|
| 2007 |
Ezzi SA, Urushitani M, Julien JP. Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. Journal of Neurochemistry. 102: 170-8. PMID 17394546 DOI: 10.1111/J.1471-4159.2007.04531.X |
0.347 |
|
| 2007 |
Urushitani M, Ezzi SA, Julien JP. Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 2495-500. PMID 17277077 DOI: 10.1073/Pnas.0606201104 |
0.412 |
|
| 2007 |
Julien JP. Mouse models of amyotrophic lateral sclerosis Drug Discovery Today: Disease Models. 3: 331-339. DOI: 10.1016/J.Ddmod.2006.12.003 |
0.435 |
|
| 2006 |
Gowing G, Dequen F, Soucy G, Julien JP. Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11397-402. PMID 17079668 DOI: 10.1523/Jneurosci.0602-06.2006 |
0.416 |
|
| 2006 |
Yuan A, Rao MV, Sasaki T, Chen Y, Kumar A, Veeranna, Liem RK, Eyer J, Peterson AC, Julien JP, Nixon RA. Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10006-19. PMID 17005864 DOI: 10.1523/Jneurosci.2580-06.2006 |
0.385 |
|
| 2006 |
Millecamps S, Robertson J, Lariviere R, Mallet J, Julien JP. Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. Journal of Neurochemistry. 98: 926-38. PMID 16787413 DOI: 10.1111/J.1471-4159.2006.03932.X |
0.744 |
|
| 2006 |
Carmen J, Gowing G, Julien JP, Kerr D. Altered immune response to CNS viral infection in mice with a conditional knock-down of macrophage-lineage cells. Glia. 54: 71-80. PMID 16691560 DOI: 10.1002/Glia.20359 |
0.377 |
|
| 2006 |
Julien JP, Kriz J. Transgenic mouse models of amyotrophic lateral sclerosis. Biochimica Et Biophysica Acta. 1762: 1013-24. PMID 16675207 DOI: 10.1016/J.Bbadis.2006.03.006 |
0.489 |
|
| 2006 |
Sasaki T, Gotow T, Shiozaki M, Sakaue F, Saito T, Julien JP, Uchiyama Y, Hisanaga S. Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants. Human Molecular Genetics. 15: 943-52. PMID 16452125 DOI: 10.1093/Hmg/Ddl011 |
0.396 |
|
| 2006 |
Urushitani M, Sik A, Sakurai T, Nukina N, Takahashi R, Julien JP. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nature Neuroscience. 9: 108-18. PMID 16369483 DOI: 10.1038/Nn1603 |
0.421 |
|
| 2006 |
Gowing G, Vallières L, Julien JP. Mouse model for ablation of proliferating microglia in acute CNS injuries. Glia. 53: 331-7. PMID 16276506 DOI: 10.1002/Glia.20288 |
0.341 |
|
| 2006 |
Veglianese P, Lo Coco D, Bao Cutrona M, Magnoni R, Pennacchini D, Pozzi B, Gowing G, Julien JP, Tortarolo M, Bendotti C. Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS. Molecular and Cellular Neurosciences. 31: 218-31. PMID 16219474 DOI: 10.1016/j.mcn.2005.09.009 |
0.326 |
|
| 2005 |
Jung C, Lee S, Ortiz D, Zhu Q, Julien JP, Shea TB. The high and middle molecular weight neurofilament subunits regulate the association of neurofilaments with kinesin: inhibition by phosphorylation of the high molecular weight subunit. Brain Research. Molecular Brain Research. 141: 151-5. PMID 16246456 DOI: 10.1016/J.Molbrainres.2005.08.009 |
0.393 |
|
| 2005 |
Millecamps S, Gentil BJ, Gros-Louis F, Rouleau G, Julien JP. Alsin is partially associated with centrosome in human cells. Biochimica Et Biophysica Acta. 1745: 84-100. PMID 16085057 DOI: 10.1016/J.Bbamcr.2004.12.008 |
0.405 |
|
| 2005 |
Julien JP, Millecamps S, Kriz J. Cytoskeletal defects in amyotrophic lateral sclerosis (motor neuron disease). Novartis Foundation Symposium. 264: 183-92; discussion 1. PMID 15773754 DOI: 10.1002/0470093765.Ch12 |
0.468 |
|
| 2005 |
Kriz J, Beaulieu JM, Julien JP, Krnjević K. Up-regulation of peripherin is associated with alterations in synaptic plasticity in CA1 and CA3 regions of hippocampus. Neurobiology of Disease. 18: 409-20. PMID 15686970 DOI: 10.1016/J.Nbd.2004.10.009 |
0.343 |
|
| 2004 |
Millecamps S, Julien JP. [35S]Methionine metabolic labeling to study axonal transport of neuronal intermediate filament proteins in vivo. Methods in Cell Biology. 78: 555-71. PMID 15646631 DOI: 10.1016/S0091-679X(04)78019-X |
0.419 |
|
| 2004 |
Gros-Louis F, Larivière R, Gowing G, Laurent S, Camu W, Bouchard JP, Meininger V, Rouleau GA, Julien JP. A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 279: 45951-6. PMID 15322088 DOI: 10.1074/Jbc.M408139200 |
0.411 |
|
| 2004 |
Nguyen MD, Shu T, Sanada K, Larivière RC, Tseng HC, Park SK, Julien JP, Tsai LH. A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons. Nature Cell Biology. 6: 595-608. PMID 15208636 DOI: 10.1038/Ncb1139 |
0.438 |
|
| 2004 |
Shalin SC, Zirrgiebel U, Honsa KJ, Julien JP, Miller FD, Kaplan DR, Sweatt JD. Neuronal MEK is important for normal fear conditioning in mice. Journal of Neuroscience Research. 75: 760-70. PMID 14994337 DOI: 10.1002/Jnr.20052 |
0.408 |
|
| 2004 |
Zhang G, Spencer PH, Jin LQ, Cohlberg JA, Beaulieu JM, Julien JP, Selzer ME. The single neurofilament subunit of lamprey may need another element for filament assembly. The Journal of Comparative Neurology. 471: 188-200. PMID 14986312 DOI: 10.1002/Cne.20026 |
0.35 |
|
| 2004 |
Nguyen MD, D'Aigle T, Gowing G, Julien JP, Rivest S. Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1340-9. PMID 14960605 DOI: 10.1523/Jneurosci.4786-03.2004 |
0.43 |
|
| 2004 |
Lariviere RC, Julien JP. Functions of intermediate filaments in neuronal development and disease. Journal of Neurobiology. 58: 131-48. PMID 14598376 DOI: 10.1002/Neu.10270 |
0.758 |
|
| 2003 |
Nguyen MD, Julien JP. Cyclin-dependent kinase 5 in amyotrophic lateral sclerosis. Neuro-Signals. 12: 215-20. PMID 14673208 DOI: 10.1159/000074623 |
0.352 |
|
| 2003 |
Yuan A, Rao MV, Kumar A, Julien JP, Nixon RA. Neurofilament transport in vivo minimally requires hetero-oligomer formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9452-8. PMID 14561875 DOI: 10.1523/Jneurosci.23-28-09452.2003 |
0.308 |
|
| 2003 |
Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (New York, N.Y.). 302: 113-7. PMID 14526083 DOI: 10.1126/Science.1086071 |
0.368 |
|
| 2003 |
Larivière RC, Beaulieu JM, Nguyen MD, Julien JP. Peripherin is not a contributing factor to motor neuron disease in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase. Neurobiology of Disease. 13: 158-66. PMID 12828939 DOI: 10.1016/S0969-9961(03)00036-6 |
0.53 |
|
| 2003 |
Kriz J, Gowing G, Julien JP. Efficient three-drug cocktail for disease induced by mutant superoxide dismutase. Annals of Neurology. 53: 429-36. PMID 12666110 DOI: 10.1002/Ana.10500 |
0.394 |
|
| 2003 |
Nguyen MD, Boudreau M, Kriz J, Couillard-Després S, Kaplan DR, Julien JP. Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2131-40. PMID 12657672 DOI: 10.1523/Jneurosci.23-06-02131.2003 |
0.45 |
|
| 2003 |
Robertson J, Doroudchi MM, Nguyen MD, Durham HD, Strong MJ, Shaw G, Julien JP, Mushynski WE. A neurotoxic peripherin splice variant in a mouse model of ALS. The Journal of Cell Biology. 160: 939-49. PMID 12642616 DOI: 10.1083/Jcb.200205027 |
0.51 |
|
| 2003 |
Beaulieu JM, Julien JP. Peripherin-mediated death of motor neurons rescued by overexpression of neurofilament NF-H proteins. Journal of Neurochemistry. 85: 248-56. PMID 12641746 DOI: 10.1046/J.1471-4159.2003.01653.X |
0.531 |
|
| 2002 |
Robertson J, Kriz J, Nguyen MD, Julien JP. Pathways to motor neuron degeneration in transgenic mouse models. Biochimie. 84: 1151-60. PMID 12595144 DOI: 10.1016/S0300-9084(02)00025-1 |
0.525 |
|
| 2002 |
Rao MV, Engle LJ, Mohan PS, Yuan A, Qiu D, Cataldo A, Hassinger L, Jacobsen S, Lee VM, Andreadis A, Julien JP, Bridgman PC, Nixon RA. Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density. The Journal of Cell Biology. 159: 279-90. PMID 12403814 DOI: 10.1083/Jcb.200205062 |
0.466 |
|
| 2002 |
Kriz J, Nguyen MD, Julien JP. Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiology of Disease. 10: 268-78. PMID 12270689 DOI: 10.1006/Nbdi.2002.0487 |
0.443 |
|
| 2002 |
Patel BN, Dunn RJ, Jeong SY, Zhu Q, Julien JP, David S. Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6578-86. PMID 12151537 DOI: 10.1523/Jneurosci.22-15-06578.2002 |
0.329 |
|
| 2002 |
Beaulieu JM, Kriz J, Julien JP. Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia. Brain Research. 946: 153-61. PMID 12137917 DOI: 10.1016/S0006-8993(02)02830-5 |
0.403 |
|
| 2002 |
Zhang Z, Casey DM, Julien JP, Xu Z. Normal dendritic arborization in spinal motoneurons requires neurofilament subunit L. The Journal of Comparative Neurology. 450: 144-52. PMID 12124759 DOI: 10.1002/Cne.10306 |
0.441 |
|
| 2002 |
Larivière RC, Nguyen MD, Ribeiro-da-Silva A, Julien JP. Reduced number of unmyelinated sensory axons in peripherin null mice. Journal of Neurochemistry. 81: 525-32. PMID 12065660 DOI: 10.1046/J.1471-4159.2002.00853.X |
0.403 |
|
| 2001 |
Nguyen MD, Julien JP, Rivest S. Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration. Annals of Neurology. 50: 630-9. PMID 11706969 DOI: 10.1002/Ana.1256 |
0.375 |
|
| 2001 |
Robertson J, Beaulieu JM, Doroudchi MM, Durham HD, Julien JP, Mushynski WE. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. The Journal of Cell Biology. 155: 217-26. PMID 11604419 DOI: 10.1083/Jcb.200107058 |
0.449 |
|
| 2001 |
Hirasawa M, Cho A, Sreenath T, Sauer B, Julien JP, Kulkarni AB. Neuron-specific expression of Cre recombinase during the late phase of brain development. Neuroscience Research. 40: 125-32. PMID 11377750 DOI: 10.1016/S0168-0102(01)00216-4 |
0.388 |
|
| 2001 |
Nguyen MD, Larivière RC, Julien JP. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron. 30: 135-47. PMID 11343650 DOI: 10.1016/S0896-6273(01)00268-9 |
0.499 |
|
| 2000 |
Kriz J, Zhu Q, Julien JP, Padjen AL. Electrophysiological properties of axons in mice lacking neurofilament subunit genes: disparity between conduction velocity and axon diameter in absence of NF-H. Brain Research. 885: 32-44. PMID 11121527 DOI: 10.1016/S0006-8993(00)02899-7 |
0.413 |
|
| 2000 |
Julien JP, Beaulieu JM. Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? Journal of the Neurological Sciences. 180: 7-14. PMID 11090858 DOI: 10.1016/S0022-510X(00)00422-6 |
0.537 |
|
| 2000 |
Nguyen MD, Larivière RC, Julien JP. Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1. Proceedings of the National Academy of Sciences of the United States of America. 97: 12306-11. PMID 11050249 DOI: 10.1073/Pnas.97.22.12306 |
0.529 |
|
| 2000 |
Couillard-Després S, Meier J, Julien JP. Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase. Neurobiology of Disease. 7: 462-70. PMID 10964615 DOI: 10.1006/Nbdi.2000.0296 |
0.512 |
|
| 2000 |
Beaulieu JM, Jacomy H, Julien JP. Formation of intermediate filament protein aggregates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5321-8. PMID 10884316 |
0.417 |
|
| 2000 |
Kriz J, Meier J, Julien JP, Padjen AL. Altered ionic conductances in axons of transgenic mouse expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis. Experimental Neurology. 163: 414-21. PMID 10833316 DOI: 10.1006/Exnr.2000.7378 |
0.467 |
|
| 2000 |
Stieber A, Gonatas JO, Collard J, Meier J, Julien J, Schweitzer P, Gonatas NK. The neuronal Golgi apparatus is fragmented in transgenic mice expressing a mutant human SOD1, but not in mice expressing the human NF-H gene. Journal of the Neurological Sciences. 173: 63-72. PMID 10675581 DOI: 10.1016/S0022-510X(99)00301-9 |
0.502 |
|
| 2000 |
Beaulieu J, Jacomy H, Julien J. Formation of Intermediate Filament Protein Aggregates with Disparate Effects in Two Transgenic Mouse Models Lacking the Neurofilament Light Subunit The Journal of Neuroscience. 20: 5321-5328. DOI: 10.1523/Jneurosci.20-14-05321.2000 |
0.523 |
|
| 2000 |
Julien J. Late-onset and selective death of motor neurons in transgenic mice overexpressing peripherin Neurobiology of Aging. 21: 213. DOI: 10.1016/S0197-4580(00)83290-X |
0.421 |
|
| 1999 |
Beaulieu JM, Nguyen MD, Julien JP. Late onset of motor neurons in mice overexpressing wild-type peripherin. The Journal of Cell Biology. 147: 531-44. PMID 15132161 DOI: 10.1083/Jcb.147.3.531 |
0.529 |
|
| 1999 |
Meier J, Couillard-Després S, Jacomy H, Gravel C, Julien JP. Extra neurofilament NF-L subunits rescue motor neuron disease caused by overexpression of the human NF-H gene in mice. Journal of Neuropathology and Experimental Neurology. 58: 1099-110. PMID 10515233 DOI: 10.1097/00005072-199910000-00009 |
0.512 |
|
| 1999 |
Julien JP. Neurofilament functions in health and disease. Current Opinion in Neurobiology. 9: 554-60. PMID 10508735 DOI: 10.1016/S0959-4388(99)00004-5 |
0.487 |
|
| 1999 |
Jacomy H, Zhu Q, Couillard-Després S, Beaulieu JM, Julien JP. Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits. Journal of Neurochemistry. 73: 972-84. PMID 10461886 DOI: 10.1046/J.1471-4159.1999.0730972.X |
0.441 |
|
| 1999 |
Yang Y, Bauer C, Strasser G, Wollman R, Julien JP, Fuchs E. Integrators of the cytoskeleton that stabilize microtubules. Cell. 98: 229-38. PMID 10428034 DOI: 10.1016/S0092-8674(00)81017-X |
0.473 |
|
| 1999 |
McLeod AL, Julien JP, Cuello AC, Krause JE, Ribeiro-da-Silva A. Ectopic substance P-immunoreactive boutons are preferentially presynaptic to neurokinin-1 receptor immunoreactive dendrites in the spinal white matter of transgenic mice. Brain Research. 836: 1-8. PMID 10415399 DOI: 10.1016/S0006-8993(99)01524-3 |
0.306 |
|
| 1999 |
Levavasseur F, Zhu Q, Julien JP. No requirement of alpha-internexin for nervous system development and for radial growth of axons. Brain Research. Molecular Brain Research. 69: 104-12. PMID 10350642 DOI: 10.1016/S0169-328X(99)00104-7 |
0.399 |
|
| 1999 |
Ma D, Descarries L, Micheva KD, Lepage Y, Julien JP, Doucet G. Severe neuronal losses with age in the parietal cortex and ventrobasal thalamus of mice transgenic for the human NF-L neurofilament protein. The Journal of Comparative Neurology. 406: 433-48. PMID 10205021 DOI: 10.1002/(Sici)1096-9861(19990419)406:4<433::Aid-Cne2>3.0.Co;2-3 |
0.427 |
|
| 1999 |
Zhu Q, Julien JP. A key role for GAP-43 in the retinotectal topographic organization. Experimental Neurology. 155: 228-42. PMID 10072298 DOI: 10.1006/Exnr.1998.6989 |
0.371 |
|
| 1999 |
Beaulieu J, Robertson J, Julien J. Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits. Biochemistry and Cell Biology. 77: 41-45. DOI: 10.1139/O99-003 |
0.348 |
|
| 1998 |
Julien JP, Couillard-Després S, Meier J. Transgenic mice in the study of ALS: the role of neurofilaments. Brain Pathology (Zurich, Switzerland). 8: 759-69. PMID 9804382 DOI: 10.1111/J.1750-3639.1998.Tb00199.X |
0.519 |
|
| 1998 |
Zhu Q, Lindenbaum M, Levavasseur F, Jacomy H, Julien JP. Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile. The Journal of Cell Biology. 143: 183-93. PMID 9763430 DOI: 10.1083/Jcb.143.1.183 |
0.461 |
|
| 1998 |
Julien JP, Mushynski WE. Neurofilaments in health and disease. Progress in Nucleic Acid Research and Molecular Biology. 61: 1-23. PMID 9752717 DOI: 10.1016/S0079-6603(08)60823-5 |
0.427 |
|
| 1998 |
Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, Cleveland DW. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 95: 9631-6. PMID 9689132 DOI: 10.1073/Pnas.95.16.9631 |
0.509 |
|
| 1998 |
Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9626-30. PMID 9689131 DOI: 10.1073/Pnas.95.16.9626 |
0.43 |
|
| 1997 |
Julien JP. Neurofilaments and motor neuron disease. Trends in Cell Biology. 7: 243-9. PMID 17708953 DOI: 10.1016/S0962-8924(97)01049-0 |
0.499 |
|
| 1997 |
Zhu Q, Couillard-Després S, Julien JP. Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments. Experimental Neurology. 148: 299-316. PMID 9398473 DOI: 10.1006/Exnr.1997.6654 |
0.425 |
|
| 1997 |
Paterno GD, Gillespie LL, Julien JP, Skup D. Regulation of neurofilament L, M and H gene expression during retinoic acid-induced neural differentiation of P19 embryonal carcinoma cells. Brain Research. Molecular Brain Research. 49: 247-54. PMID 9387884 DOI: 10.1016/S0169-328X(97)00157-5 |
0.355 |
|
| 1997 |
Lazzaro MA, Albert PR, Julien JP. A novel cdc2-related protein kinase expressed in the nervous system. Journal of Neurochemistry. 69: 348-64. PMID 9202329 DOI: 10.1046/J.1471-4159.1997.69010348.X |
0.343 |
|
| 1996 |
Kuchel GA, Poon T, Irshad K, Richard C, Julien JP, Cowen T. Decreased neurofilament gene expression is an index of selective axonal hypotrophy in ageing. Neuroreport. 7: 1353-9. PMID 8856674 DOI: 10.1097/00001756-199605310-00004 |
0.418 |
|
| 1996 |
Rouleau GA, Clark AW, Rooke K, Pramatarova A, Krizus A, Suchowersky O, Julien JP, Figlewicz D. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Annals of Neurology. 39: 128-31. PMID 8572658 DOI: 10.1002/Ana.410390119 |
0.39 |
|
| 1995 |
Julien JP. A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 593-7. PMID 8714677 DOI: 10.1139/O95-064 |
0.542 |
|
| 1995 |
Charron G, Guy LG, Bazinet M, Julien JP. Multiple neuron-specific enhancers in the gene coding for the human neurofilament light chain. The Journal of Biological Chemistry. 270: 30604-10. PMID 8530496 DOI: 10.1074/Jbc.270.51.30604 |
0.427 |
|
| 1995 |
Mathieu JF, Ma D, Descarries L, Vallée A, Parent A, Julien JP, Doucet G. CNS distribution and overexpression of neurofilament light proteins (NF-L) in mice transgenic for the human NF-L: aberrant accumulation in thalamic perikarya. Experimental Neurology. 132: 134-46. PMID 7720822 DOI: 10.1016/0014-4886(95)90067-5 |
0.398 |
|
| 1995 |
Charron G, Julien JP, Bibor-Hardy V. Neuron specificity of the neurofilament light promoter in transgenic mice requires the presence of DNA unwinding elements. The Journal of Biological Chemistry. 270: 25739-45. PMID 7592755 DOI: 10.1074/Jbc.270.43.25739 |
0.342 |
|
| 1995 |
Julien JP, Côté F, Collard JF. Mice overexpressing the human neurofilament heavy gene as a model of ALS. Neurobiology of Aging. 16: 487-90; discussion 4. PMID 7566355 DOI: 10.1016/0197-4580(94)00170-6 |
0.456 |
|
| 1995 |
Collard JF, Côté F, Julien JP. Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature. 375: 61-4. PMID 7536898 DOI: 10.1038/375061A0 |
0.51 |
|
| 1994 |
Côté F, Collard JF, Houle D, Julien JP. Copy-dependent and correct developmental expression of the human neurofilament heavy gene in transgenic mice. Brain Research. Molecular Brain Research. 26: 99-105. PMID 7854073 DOI: 10.1016/0169-328X(94)90079-5 |
0.404 |
|
| 1994 |
Figlewicz DA, Krizus A, Martinoli MG, Meininger V, Dib M, Rouleau GA, Julien JP. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Human Molecular Genetics. 3: 1757-61. PMID 7849698 DOI: 10.1093/Hmg/3.10.1757 |
0.413 |
|
| 1994 |
Leconte L, Semonin O, Zvara A, Boisseau S, Poujeol C, Julien JP, Simonneau M. Both upstream and intragenic sequences of the human neurofilament light gene direct expression of lacZ in neurons of transgenic mouse embryos. Journal of Molecular Neuroscience : Mn. 5: 273-95. PMID 7577369 DOI: 10.1007/Bf02736727 |
0.387 |
|
| 1993 |
Beaudet L, Côté F, Houle D, Julien JP. Different posttranscriptional controls for the human neurofilament light and heavy genes in transgenic mice. Brain Research. Molecular Brain Research. 18: 23-31. PMID 8479288 DOI: 10.1016/0169-328X(93)90170-T |
0.409 |
|
| 1993 |
Côté F, Collard JF, Julien JP. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell. 73: 35-46. PMID 8462101 DOI: 10.1016/0092-8674(93)90158-M |
0.443 |
|
| 1993 |
Figlewicz DA, Rouleau GA, Krizus A, Julien JP. Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene. Gene. 132: 297-300. PMID 8224877 DOI: 10.1016/0378-1119(93)90211-K |
0.305 |
|
| 1993 |
Friedman HCH, Julien JP. Transgenic Mouse Approaches for Analysis of the Nervous System Neuroprotocols. 3: 69-80. DOI: 10.1006/Ncmn.1993.1039 |
0.41 |
|
| 1992 |
Beaudet L, Charron G, Houle D, Tretjakoff I, Peterson A, Julien JP. Intragenic regulatory elements contribute to transcriptional control of the neurofilament light gene. Gene. 116: 205-14. PMID 1634118 DOI: 10.1016/0378-1119(92)90517-S |
0.361 |
|
| 1992 |
Beaudet L, Charron G, Julien JP. Origin of the two mRNA species for the human neurofilament light gene. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 279-84. PMID 1497855 DOI: 10.1139/O92-044 |
0.3 |
|
| 1991 |
Vidal-Sanz M, Villegas-Pérez MP, Carter DA, Julien JP, Peterson A, Aguayo AJ. Expression of Human Neurofilament-light Transgene in Mouse Neurons Transplanted into the Brain of Adult Rats. The European Journal of Neuroscience. 3: 758-763. PMID 12106461 DOI: 10.1111/J.1460-9568.1991.Tb01671.X |
0.375 |
|
| 1990 |
Clark AW, Tran PM, Parhad IM, Krekoski CA, Julien JP. Neuronal gene expression in amyotrophic lateral sclerosis. Brain Research. Molecular Brain Research. 7: 75-83. PMID 2153897 DOI: 10.1016/0169-328X(90)90076-P |
0.419 |
|
| 1989 |
Clark AW, Krekoski CA, Parhad IM, Liston D, Julien JP, Hoar DI. Altered expression of genes for amyloid and cytoskeletal proteins in Alzheimer cortex. Annals of Neurology. 25: 331-9. PMID 2469380 DOI: 10.1002/Ana.410250404 |
0.328 |
|
| 1988 |
Julien JP, Côté F, Beaudet L, Sidky M, Flavell D, Grosveld F, Mushynski W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit. Gene. 68: 307-14. PMID 3220257 DOI: 10.1016/0378-1119(88)90033-9 |
0.33 |
|
| 1987 |
Julien JP, Tretjakoff I, Beaudet L, Peterson A. Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system. Genes & Development. 1: 1085-95. PMID 2828164 DOI: 10.1101/GAD.1.10.1085 |
0.325 |
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| 1986 |
Julien JP, Meyer D, Flavell D, Hurst J, Grosveld F. Cloning and developmental expression of the murine neurofilament gene family. Brain Research. 387: 243-50. PMID 3103856 DOI: 10.1016/0169-328X(86)90030-6 |
0.332 |
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