Jonathan A. Javitch, MD, PhD - Publications

Affiliations: 
Center for Molecular Recognition Columbia University, New York, NY 
Area:
G-protein coupled receptors and neurotransmitter transporters
Website:
https://www.columbiapsychiatry.org/profile/jonathan-javitch-md

215 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fitzgerald GA, Terry DS, Warren AL, Quick M, Javitch JA, Blanchard SC. Quantifying secondary transport at single-molecule resolution. Nature. 575: 528-534. PMID 31723269 DOI: 10.1038/s41586-019-1747-5  0.32
2019 Klein Herenbrink C, Verma R, Lim HD, Kopinathan A, Keen A, Shonberg J, Draper-Joyce CJ, Scammells PJ, Christopoulos A, Javitch JA, Capuano B, Shi L, Lane JR. Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole. Acs Chemical Biology. PMID 31339684 DOI: 10.1021/acschembio.9b00342  0.68
2019 LeVine MV, Terry DS, Khelashvili G, Siegel ZS, Quick M, Javitch JA, Blanchard SC, Weinstein H. The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31324743 DOI: 10.1073/pnas.1903020116  0.68
2019 Kruegel AC, Uprety R, Grinnell SG, Langreck C, Pekarskaya EA, Le Rouzic V, Ansonoff M, Gassaway MM, Pintar JE, Pasternak GW, Javitch JA, Majumdar S, Sames D. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. Acs Central Science. 5: 992-1001. PMID 31263758 DOI: 10.1021/acscentsci.9b00141  0.44
2019 Farino ZJ, Morgenstern TJ, Maffei A, Quick M, De Solis AJ, Wiriyasermkul P, Freyberg RJ, Aslanoglou D, Sorisio D, Inbar BP, Free RB, Donthamsetti P, Mosharov EV, Kellendonk C, Schwartz GJ, ... ... Javitch JA, et al. New roles for dopamine D and D receptors in pancreatic beta cell insulin secretion. Molecular Psychiatry. PMID 30626912 DOI: 10.1038/s41380-018-0344-6  0.6
2018 Donthamsetti P, Gallo EF, Buck DC, Stahl EL, Zhu Y, Lane JR, Bohn LM, Neve KA, Kellendonk C, Javitch JA. Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation. Molecular Psychiatry. PMID 30120413 DOI: 10.1038/s41380-018-0212-4  0.6
2018 Quick M, Abramyan AM, Wiriyasermkul P, Weinstein H, Shi L, Javitch JA. The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites. Proceedings of the National Academy of Sciences of the United States of America. PMID 30082383 DOI: 10.1073/pnas.1717444115  0.68
2018 Yano H, Cai NS, Javitch JA, Ferré S. Luciferase complementation based-detection of G-protein-coupled receptor activity. Biotechniques. 65: 9-14. PMID 30014734 DOI: 10.2144/btn-2018-0039  0.56
2018 Abramyan AM, Quick M, Xue C, Javitch JA, Shi L. Exploring substrate binding in the extracellular vestibule of MhsT by atomistic simulations and Markov models. Journal of Chemical Information and Modeling. PMID 29851339 DOI: 10.1021/acs.jcim.8b00175  0.68
2018 Marcott PF, Gong S, Donthamsetti P, Grinnell SG, Nelson MN, Newman AH, Birnbaumer L, Martemyanov KA, Javitch JA, Ford CP. Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens. Neuron. PMID 29656874 DOI: 10.1016/j.neuron.2018.03.038  0.36
2018 Gallo EF, Meszaros J, Sherman JD, Chohan MO, Teboul E, Choi CS, Moore H, Javitch JA, Kellendonk C. Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum. Nature Communications. 9: 1086. PMID 29540712 DOI: 10.1038/s41467-018-03272-2  0.6
2018 Yano H, Cai NS, Xu M, Verma RK, Rea W, Hoffman AF, Shi L, Javitch JA, Bonci A, Ferré S. Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor. Nature Communications. 9: 486. PMID 29402888 DOI: 10.1038/s41467-017-02606-w  0.68
2018 Draper-Joyce CJ, Verma RK, Michino M, Shonberg J, Kopinathan A, Klein Herenbrink C, Scammells PJ, Capuano B, Abramyan AM, Thal DM, Javitch JA, Christopoulos A, Shi L, Lane JR. The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions. Scientific Reports. 8: 1208. PMID 29352161 DOI: 10.1038/s41598-018-19642-1  0.68
2018 Verma RK, Abramyan AM, Michino M, Free RB, Sibley DR, Javitch JA, Lane JR, Shi L. The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors. Plos Computational Biology. 14: e1005948. PMID 29337986 DOI: 10.1371/journal.pcbi.1005948  0.68
2018 Terry DS, Kolster RA, Quick M, LeVine MV, Khelashvili G, Zhou Z, Weinstein H, Javitch JA, Blanchard SC. A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport. Nature Communications. 9: 230. PMID 29335402 DOI: 10.1038/s41467-017-02202-y  0.68
2018 Draper-Joyce CJ, Michino M, Verma RK, Herenbrink CK, Shonberg J, Kopinathan A, Scammells PJ, Capuano B, Thal DM, Javitch JA, Christopoulos A, Shi L, Lane JR. The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2 receptor. Biochemical Pharmacology. PMID 29325769 DOI: 10.1016/j.bcp.2018.01.002  0.68
2017 Donthamsetti P, Winter N, Schönberger M, Levitz J, Stanley C, Javitch JA, Isacoff EY, Trauner D. Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist. Journal of the American Chemical Society. PMID 29166564 DOI: 10.1021/jacs.7b07659  0.36
2017 Clark AM, Leroy F, Martyniuk KM, Feng W, McManus E, Bailey MR, Javitch JA, Balsam PD, Kellendonk C. Dopamine D2 Receptors in the Paraventricular Thalamus Attenuate Cocaine Locomotor Sensitization. Eneuro. 4. PMID 29071300 DOI: 10.1523/ENEURO.0227-17.2017  0.6
2017 Yano H, Provasi D, Cai NS, Filizola M, Ferre S, Javitch JA. Development of novel biosensors to study receptor-mediated activation of Gs and Golf. The Journal of Biological Chemistry. PMID 29042444 DOI: 10.1074/jbc.M117.800698  0.68
2017 Sykes DA, Moore H, Stott L, Holliday N, Javitch JA, Lane JR, Charlton SJ. Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors. Nature Communications. 8: 763. PMID 28970469 DOI: 10.1038/s41467-017-00716-z  0.6
2017 Gregorio GG, Masureel M, Hilger D, Terry DS, Juette M, Zhao H, Zhou Z, Perez-Aguilar JM, Hauge M, Mathiasen S, Javitch JA, Weinstein H, Kobilka BK, Blanchard SC. Single-molecule analysis of ligand efficacy in β2AR-G-protein activation. Nature. PMID 28607487 DOI: 10.1038/nature22354  0.68
2017 Stolzenberg S, Li Z, Quick M, Malinauskaite L, Nissen P, Weinstein H, Javitch JA, Shi L. The Role of TM5 in Na2 Release and the Conformational Transition of Neurotransmitter:Sodium Symporters toward the Inward-Open State. The Journal of Biological Chemistry. PMID 28320858 DOI: 10.1074/jbc.M116.757153  0.68
2017 Samuels BA, Nautiyal KM, Kruegel AC, Levinstein MR, Magalong VM, Gassaway MM, Grinnell SG, Han J, Ansonoff MA, Pintar JE, Javitch JA, Sames D, Hen R. The Behavioral Effects of the Antidepressant Tianeptine Require the Mu Opioid Receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28303899 DOI: 10.1038/npp.2017.60  0.44
2016 Michino M, Boateng CA, Donthamsetti P, Yano H, Bakare OM, Bonifazi A, Ellenberger MP, Keck TM, Kumar V, Zhu C, Verma R, Deschamps JR, Javitch JA, Newman AH, Shi L. Towards understanding the structural basis of partial agonism at the dopamine D3 receptor. Journal of Medicinal Chemistry. PMID 27983845 DOI: 10.1021/acs.jmedchem.6b01148  0.68
2016 Khelashvili G, Schmidt SG, Shi L, Javitch JA, Gether U, Loland CJ, Weinstein H. Conformational dynamics on the extracellular side of LeuT controlled by Na+ and K+ ions and the protonation state of E290. The Journal of Biological Chemistry. PMID 27474737 DOI: 10.1074/jbc.M116.731455  0.68
2016 Kruegel AC, Gassaway MM, Kapoor A, Váradi A, Majumdar S, Filizola M, Javitch JA, Sames D. Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators. Journal of the American Chemical Society. PMID 27192616 DOI: 10.1021/jacs.6b00360  0.68
2016 Zou MF, Keck TM, Kumar V, Donthamsetti P, Michino M, Burzynski C, Schweppe C, Bonifazi A, Free RB, Sibley DR, Janowsky A, Shi L, Javitch JA, Newman AH. Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity. Journal of Medicinal Chemistry. PMID 27035329 DOI: 10.1021/acs.jmedchem.5b01612  1
2016 Klein Herenbrink C, Sykes DA, Donthamsetti P, Canals M, Coudrat T, Shonberg J, Scammells PJ, Capuano B, Sexton PM, Charlton SJ, Javitch JA, Christopoulos A, Lane JR. The role of kinetic context in apparent biased agonism at GPCRs. Nature Communications. 7: 10842. PMID 26905976 DOI: 10.1038/ncomms10842  1
2016 Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, ... ... Javitch JA, et al. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nature Communications. 7: 10652. PMID 26879809 DOI: 10.1038/ncomms10652  1
2016 Farino ZJ, Morgenstern TJ, Vallaghe J, Gregor N, Donthamsetti P, Harris PE, Pierre N, Freyberg R, Charrier-Savournin F, Javitch JA, Freyberg Z. Development of a Rapid Insulin Assay by Homogenous Time-Resolved Fluorescence. Plos One. 11: e0148684. PMID 26849707 DOI: 10.1371/journal.pone.0148684  0.36
2016 LeVine MV, Khelashvili G, Shi L, Quick M, Javitch JA, Weinstein H. The role of annular lipids in the functional properties of leucine transporter LeuT proteomicelles. Biochemistry. PMID 26811944 DOI: 10.1021/acs.biochem.5b01268  1
2015 Billesbølle CB, Krüger MB, Shi L, Quick M, Li Z, Stolzenberg S, Kniazeff J, Gotfryd K, Mortensen JS, Javitch JA, Weinstein H, Loland CJ, Gether U. Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter:sodium symporter. The Journal of Biological Chemistry. PMID 26363074 DOI: 10.1074/jbc.M115.677658  1
2015 Donthamsetti P, Quejada JR, Javitch JA, Gurevich VV, Lambert NA. Using Bioluminescence Resonance Energy Transfer (BRET) to Characterize Agonist-Induced Arrestin Recruitment to Modified and Unmodified G Protein-Coupled Receptors. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 70: 2.14.1-2.14.14. PMID 26331887 DOI: 10.1002/0471141755.ph0214s70  0.36
2015 Boateng CA, Bakare OM, Zhan J, Banala AK, Burzynski C, Pommier E, Keck TM, Donthamsetti P, Javitch JA, Rais R, Slusher BS, Xi ZX, Newman AH. High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice. Journal of Medicinal Chemistry. 58: 6195-213. PMID 26203768 DOI: 10.1021/acs.jmedchem.5b00776  0.36
2015 Stolzenberg S, Quick M, Zhao C, Gotfryd K, Khelashvili G, Gether U, Loland CJ, Javitch JA, Noskov S, Weinstein H, Shi L. Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters. The Journal of Biological Chemistry. 290: 13992-4003. PMID 25869126 DOI: 10.1074/jbc.M114.625343  1
2015 Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, et al. Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling. Nature Chemical Biology. 11: 271-9. PMID 25706338 DOI: 10.1038/nchembio.1766  1
2015 Gallo EF, Salling MC, Feng B, Morón JA, Harrison NL, Javitch JA, Kellendonk C. Upregulation of dopamine D2 receptors in the nucleus accumbens indirect pathway increases locomotion but does not reduce alcohol consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1609-18. PMID 25578797 DOI: 10.1038/npp.2015.11  1
2015 Frederick AL, Yano H, Trifilieff P, Vishwasrao HD, Biezonski D, Mészáros J, Urizar E, Sibley DR, Kellendonk C, Sonntag KC, Graham DL, Colbran RJ, Stanwood GD, Javitch JA. Evidence against dopamine D1/D2 receptor heteromers. Molecular Psychiatry. PMID 25560761 DOI: 10.1038/mp.2014.166  1
2015 Biezonski DK, Trifilieff P, Meszaros J, Javitch JA, Kellendonk C. Evidence for limited D1 and D2 receptor coexpression and colocalization within the dorsal striatum of the neonatal mouse. The Journal of Comparative Neurology. 523: 1175-89. PMID 25556545 DOI: 10.1002/cne.23730  1
2015 Michino M, Beuming T, Donthamsetti P, Newman AH, Javitch JA, Shi L. What can crystal structures of aminergic receptors tell us about designing subtype-selective ligands? Pharmacological Reviews. 67: 198-213. PMID 25527701 DOI: 10.1124/pr.114.009944  0.68
2015 Boateng CA, Bakare OM, Zhan J, Banala AK, Burzynski C, Pommier E, Keck TM, Donthamsetti P, Javitch JA, Rais R, Slusher BS, Xi ZX, Newman AH. High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice Journal of Medicinal Chemistry. 58: 6195-6213. DOI: 10.1021/acs.jmedchem.5b00776  1
2014 Clayton CC, Donthamsetti P, Lambert NA, Javitch JA, Neve KA. Mutation of three residues in the third intracellular loop of the dopamine D2 receptor creates an internalization-defective receptor. The Journal of Biological Chemistry. 289: 33663-75. PMID 25336643 DOI: 10.1074/jbc.M114.605378  1
2014 Malinauskaite L, Quick M, Reinhard L, Lyons JA, Yano H, Javitch JA, Nissen P. A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters. Nature Structural & Molecular Biology. 21: 1006-12. PMID 25282149 DOI: 10.1038/nsmb.2894  0.56
2014 Gaskill PJ, Yano HH, Kalpana GV, Javitch JA, Berman JW. Dopamine receptor activation increases HIV entry into primary human macrophages. Plos One. 9: e108232. PMID 25268786 DOI: 10.1371/journal.pone.0108232  1
2014 Lane JR, Donthamsetti P, Shonberg J, Draper-Joyce CJ, Dentry S, Michino M, Shi L, López L, Scammells PJ, Capuano B, Sexton PM, Javitch JA, Christopoulos A. A new mechanism of allostery in a G protein-coupled receptor dimer. Nature Chemical Biology. 10: 745-52. PMID 25108820 DOI: 10.1038/nchembio.1593  1
2014 Gassaway MM, Rives ML, Kruegel AC, Javitch JA, Sames D. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Translational Psychiatry. 4: e411. PMID 25026323 DOI: 10.1038/tp.2014.30  1
2014 Lambert NA, Javitch JA. Rebuttal from Nevin A. Lambert and Jonathan A. Javitch. The Journal of Physiology. 592: 2449. PMID 24931947 DOI: 10.1113/jphysiol.2014.274241  1
2014 Lambert NA, Javitch JA. CrossTalk opposing view: Weighing the evidence for class A GPCR dimers, the jury is still out. The Journal of Physiology. 592: 2443-5. PMID 24931945 DOI: 10.1113/jphysiol.2014.272997  1
2014 Hamilton PJ, Belovich AN, Khelashvili G, Saunders C, Erreger K, Javitch JA, Sitte HH, Weinstein H, Matthies HJ, Galli A. PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein. Nature Chemical Biology. 10: 582-9. PMID 24880859 DOI: 10.1038/nchembio.1545  1
2014 Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, ... ... Javitch JA, et al. Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor. Molecular Pharmacology. 86: 96-105. PMID 24755247 DOI: 10.1124/mol.113.090563  1
2014 Kazmier K, Sharma S, Quick M, Islam SM, Roux B, Weinstein H, Javitch JA, McHaourab HS. Conformational dynamics of ligand-dependent alternating access in LeuT. Nature Structural & Molecular Biology. 21: 472-9. PMID 24747939 DOI: 10.1038/nsmb.2816  1
2014 Dehnes Y, Shan J, Beuming T, Shi L, Weinstein H, Javitch JA. Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation. Neurochemistry International. 73: 4-15. PMID 24576496 DOI: 10.1016/j.neuint.2014.02.003  1
2014 White KL, Scopton AP, Rives ML, Bikbulatov RV, Polepally PR, Brown PJ, Kenakin T, Javitch JA, Zjawiony JK, Roth BL. Identification of novel functionally selective κ-opioid receptor scaffolds. Molecular Pharmacology. 85: 83-90. PMID 24113749 DOI: 10.1124/mol.113.089649  1
2014 Pizzo AB, Karam CS, Zhang Y, Ma CL, McCabe BD, Javitch JA. Amphetamine-induced behavior requires CaMKII-dependent dopamine transporter phosphorylation. Molecular Psychiatry. 19: 279-81. PMID 23508128 DOI: 10.1038/mp.2013.29  1
2013 Michino M, Donthamsetti P, Beuming T, Banala A, Duan L, Roux T, Han Y, Trinquet E, Newman AH, Javitch JA, Shi L. A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors. Molecular Pharmacology. 84: 854-64. PMID 24061855 DOI: 10.1124/mol.113.087833  1
2013 Khelashvili G, LeVine MV, Shi L, Quick M, Javitch JA, Weinstein H. The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site. Journal of the American Chemical Society. 135: 14266-75. PMID 23980525 DOI: 10.1021/ja405984v  1
2013 Wang Y, Javitch JA. Getting to grips with ammonium. Elife. 2: e01029. PMID 23840933 DOI: 10.7554/eLife.01029  1
2013 Gavalas A, Lan TH, Liu Q, Corrêa IR, Javitch JA, Lambert NA. Segregation of family A G protein-coupled receptor protomers in the plasma membrane. Molecular Pharmacology. 84: 346-52. PMID 23778362 DOI: 10.1124/mol.113.086868  1
2013 Trifilieff P, Feng B, Urizar E, Winiger V, Ward RD, Taylor KM, Martinez D, Moore H, Balsam PD, Simpson EH, Javitch JA. Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation. Molecular Psychiatry. 18: 1025-33. PMID 23711983 DOI: 10.1038/mp.2013.57  1
2013 Kantcheva AK, Quick M, Shi L, Winther AM, Stolzenberg S, Weinstein H, Javitch JA, Nissen P. Chloride binding site of neurotransmitter sodium symporters. Proceedings of the National Academy of Sciences of the United States of America. 110: 8489-94. PMID 23641004 DOI: 10.1073/pnas.1221279110  1
2013 Rives ML, Javitch JA. Sensing conformational changes in metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 110: 5742-3. PMID 23542381 DOI: 10.1073/pnas.1303736110  1
2013 Negri A, Rives ML, Caspers MJ, Prisinzano TE, Javitch JA, Filizola M. Discovery of a novel selective kappa-opioid receptor agonist using crystal structure-based virtual screening. Journal of Chemical Information and Modeling. 53: 521-6. PMID 23461591 DOI: 10.1021/ci400019t  1
2013 Pizzo AB, Karam CS, Zhang Y, Yano H, Freyberg RJ, Karam DS, Freyberg Z, Yamamoto A, McCabe BD, Javitch JA. The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila. Molecular Psychiatry. 18: 824-33. PMID 22710269 DOI: 10.1038/mp.2012.82  1
2013 Newman AH, Banala AK, Donthamsetti P, Cao J, Michino M, Luedtke RR, Javitch JA, Shi L. Drug Design for Addiction - Molecular Determinants of Selectivity and Efficacy at the Dopamine D3 Receptor Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 181-182. DOI: 10.1016/B978-0-12-800044-1.00163-X  1
2013 Free RB, Conroy JL, Roof RA, Doyle T, Han Y, Donthamsetti P, Javitch JA, Southall N, Emmitte K, Lindsley C, Ferrer M, Sibley DR. High-Throughput Screening for Modulators of the D2 Dopamine Receptor Yields Unique and Selective Pharmacological Chemotypes Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 115. DOI: 10.1016/B978-0-12-800044-1.00101-X  1
2013 Donthamsetti PC, Javitch JA. Deciphering the Functionally Selective Properties of D2R Ligands Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 110. DOI: 10.1016/B978-0-12-800044-1.00096-9  1
2013 Javitch J. Cross-Talk between G Protein-Coupled Receptors: Challenges of Distinguishing Upstream from Downstream Mechanisms Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 93-94. DOI: 10.1016/B978-0-12-800044-1.00080-5  1
2013 Yano H, Provasi D, Filizola M, Javitch J. Towards Better Understanding of G(s) Coupling in Catecholamine Receptors Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 89-90. DOI: 10.1016/B978-0-12-800044-1.00076-3  1
2013 Pizzo AB, Karam CS, Zhang Y, Yamamoto A, McCabe BD, Javitch JA. The Membrane-Raft Protein Flotillin-1 is Essential in Dopamine Neurons for Amphetamine-Induced Behavior in Drosophila Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 58. DOI: 10.1016/B978-0-12-800044-1.00052-0  1
2012 Simpson N, Maffei A, Freeby M, Burroughs S, Freyberg Z, Javitch J, Leibel RL, Harris PE. Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro. Molecular Endocrinology (Baltimore, Md.). 26: 1757-72. PMID 22915827 DOI: 10.1210/me.2012-1101  1
2012 Rives ML, Rossillo M, Liu-Chen LY, Javitch JA. 6'-Guanidinonaltrindole (6'-GNTI) is a G protein-biased κ-opioid receptor agonist that inhibits arrestin recruitment. The Journal of Biological Chemistry. 287: 27050-4. PMID 22736766 DOI: 10.1074/jbc.C112.387332  1
2012 Geng Y, Xiong D, Mosyak L, Malito DL, Kniazeff J, Chen Y, Burmakina S, Quick M, Bush M, Javitch JA, Pin JP, Fan QR. Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2. Nature Neuroscience. 15: 970-8. PMID 22660477 DOI: 10.1038/nn.3133  1
2012 Newman AH, Beuming T, Banala AK, Donthamsetti P, Pongetti K, LaBounty A, Levy B, Cao J, Michino M, Luedtke RR, Javitch JA, Shi L. Molecular determinants of selectivity and efficacy at the dopamine D3 receptor. Journal of Medicinal Chemistry. 55: 6689-99. PMID 22632094 DOI: 10.1021/jm300482h  1
2012 Conrad KL, Davis AR, Silberman Y, Sheffler DJ, Shields AD, Saleh SA, Sen N, Matthies HJ, Javitch JA, Lindsley CW, Winder DG. Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine-independent processes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2253-66. PMID 22617356 DOI: 10.1038/npp.2012.76  1
2012 Quick M, Shi L, Zehnpfennig B, Weinstein H, Javitch JA. Experimental conditions can obscure the second high-affinity site in LeuT. Nature Structural & Molecular Biology. 19: 207-11. PMID 22245968 DOI: 10.1038/nsmb.2197  1
2012 Altman RB, Terry DS, Zhou Z, Zheng Q, Geggier P, Kolster RA, Zhao Y, Javitch JA, Warren JD, Blanchard SC. Cyanine fluorophore derivatives with enhanced photostability. Nature Methods. 9: 68-71. PMID 22081126 DOI: 10.1038/nmeth.1774  1
2012 Skinbjerg M, Sibley DR, Javitch JA, Abi-Dargham A. Imaging the high-affinity state of the dopamine D2 receptor in vivo: fact or fiction? Biochemical Pharmacology. 83: 193-8. PMID 21945484 DOI: 10.1016/j.bcp.2011.09.008  1
2011 Rappold PM, Cui M, Chesser AS, Tibbett J, Grima JC, Duan L, Sen N, Javitch JA, Tieu K. Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3. Proceedings of the National Academy of Sciences of the United States of America. 108: 20766-71. PMID 22143804 DOI: 10.1073/pnas.1115141108  1
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, ... ... Javitch JA, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/pnas.1104807108  1
2011 Trifilieff P, Rives ML, Urizar E, Piskorowski RA, Vishwasrao HD, Castrillon J, Schmauss C, Slättman M, Gullberg M, Javitch JA. Detection of antigen interactions ex vivo by proximity ligation assay: endogenous dopamine D2-adenosine A2A receptor complexes in the striatum. Biotechniques. 51: 111-8. PMID 21806555 DOI: 10.2144/000113719  1
2011 Urizar E, Yano H, Kolster R, Galés C, Lambert N, Javitch JA. CODA-RET reveals functional selectivity as a result of GPCR heteromerization. Nature Chemical Biology. 7: 624-30. PMID 21785426 DOI: 10.1038/nchembio.623  1
2011 Zhao Y, Terry DS, Shi L, Quick M, Weinstein H, Blanchard SC, Javitch JA. Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue. Nature. 474: 109-13. PMID 21516104 DOI: 10.1038/nature09971  1
2011 Cao Y, Jin X, Levin EJ, Huang H, Zong Y, Quick M, Weng J, Pan Y, Love J, Punta M, Rost B, Hendrickson WA, Javitch JA, Rajashankar KR, Zhou M. Crystal structure of a phosphorylation-coupled saccharide transporter. Nature. 473: 50-4. PMID 21471968 DOI: 10.1038/nature09939  1
2011 Cao Y, Jin X, Huang H, Derebe MG, Levin EJ, Kabaleeswaran V, Pan Y, Punta M, Love J, Weng J, Quick M, Ye S, Kloss B, Bruni R, Martinez-Hackert E, ... ... Javitch JA, et al. Crystal structure of a potassium ion transporter, TrkH. Nature. 471: 336-40. PMID 21317882 DOI: 10.1038/nature09731  1
2011 Shan J, Javitch JA, Shi L, Weinstein H. The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter. Plos One. 6: e16350. PMID 21298009 DOI: 10.1371/journal.pone.0016350  1
2011 Johnston JM, Aburi M, Provasi D, Bortolato A, Urizar E, Lambert NA, Javitch JA, Filizola M. Making structural sense of dimerization interfaces of delta opioid receptor homodimers. Biochemistry. 50: 1682-90. PMID 21261298 DOI: 10.1021/bi101474v  1
2011 Slifstein M, Suckow RF, Javitch JA, Cooper T, Lieberman J, Abi-Dargham A. Characterization of in vivo pharmacokinetic properties of the dopamine D1 receptor agonist DAR-0100A in nonhuman primates using PET with [11C] NNC112 and [11C] raclopride. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 293-304. PMID 20571519 DOI: 10.1038/jcbfm.2010.91  1
2011 Lyon GJ, Abi-Dargham A, Moore H, Lieberman JA, Javitch JA, Sulzer D. Presynaptic regulation of dopamine transmission in schizophrenia. Schizophrenia Bulletin. 37: 108-17. PMID 19525353 DOI: 10.1093/schbul/sbp010  1
2010 Speed NK, Matthies HJ, Kennedy JP, Vaughan RA, Javitch JA, Russo SJ, Lindsley CW, Niswender K, Galli A. Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression. Acs Chemical Neuroscience. 1: 476-81. PMID 22778840 DOI: 10.1021/cn100031t  1
2010 Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.). 330: 1091-5. PMID 21097933 DOI: 10.1126/science.1197410  1
2010 Silvano E, Millan MJ, Mannoury la Cour C, Han Y, Duan L, Griffin SA, Luedtke RR, Aloisi G, Rossi M, Zazzeroni F, Javitch JA, Maggio R. The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptors. Molecular Pharmacology. 78: 925-34. PMID 20702763 DOI: 10.1124/mol.110.065755  1
2010 Zhang P, Cyriac G, Kopajtic T, Zhao Y, Javitch JA, Katz JL, Newman AH. Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters. Journal of Medicinal Chemistry. 53: 6112-21. PMID 20672825 DOI: 10.1021/jm1005034  1
2010 Gkountelias K, Papadokostaki M, Javitch JA, Liapakis G. Exploring the binding site crevice of a family B G protein-coupled receptor, the type 1 corticotropin releasing factor receptor. Molecular Pharmacology. 78: 785-93. PMID 20664003 DOI: 10.1124/mol.110.065474  1
2010 Albizu L, Cottet M, Kralikova M, Stoev S, Seyer R, Brabet I, Roux T, Bazin H, Bourrier E, Lamarque L, Breton C, Rives ML, Newman A, Javitch J, Trinquet E, et al. Time-resolved FRET between GPCR ligands reveals oligomers in native tissues. Nature Chemical Biology. 6: 587-94. PMID 20622858 DOI: 10.1038/nchembio.396  1
2010 Karam CS, Ballon JS, Bivens NM, Freyberg Z, Girgis RR, Lizardi-Ortiz JE, Markx S, Lieberman JA, Javitch JA. Signaling pathways in schizophrenia: emerging targets and therapeutic strategies. Trends in Pharmacological Sciences. 31: 381-90. PMID 20579747 DOI: 10.1016/j.tips.2010.05.004  1
2010 Claxton DP, Quick M, Shi L, de Carvalho FD, Weinstein H, Javitch JA, McHaourab HS. Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters. Nature Structural & Molecular Biology. 17: 822-9. PMID 20562855 DOI: 10.1038/nsmb.1854  1
2010 Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, et al. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics (Oxford, England). 26: 1804-5. PMID 20501551 DOI: 10.1093/bioinformatics/btq264  1
2010 Zhao Y, Terry D, Shi L, Weinstein H, Blanchard SC, Javitch JA. Single-molecule dynamics of gating in a neurotransmitter transporter homologue. Nature. 465: 188-93. PMID 20463731 DOI: 10.1038/nature09057  1
2010 Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies HJ, Sen N, Jessen T, Colbran RJ, Caron MG, Javitch JA, Blakely RD, Galli A. Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6048-57. PMID 20427663 DOI: 10.1523/JNEUROSCI.5094-09.2010  1
2010 Zhao Y, Quick M, Shi L, Mehler EL, Weinstein H, Javitch JA. Substrate-dependent proton antiport in neurotransmitter:sodium symporters. Nature Chemical Biology. 6: 109-16. PMID 20081826 DOI: 10.1038/nchembio.284  1
2010 Guo N, Guo W, Kralikova M, Jiang M, Schieren I, Narendran R, Slifstein M, Abi-Dargham A, Laruelle M, Javitch JA, Rayport S. Impact of D2 receptor internalization on binding affinity of neuroimaging radiotracers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 806-17. PMID 19956086 DOI: 10.1038/npp.2009.189  1
2010 Freyberg Z, Ferrando SJ, Javitch JA. Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action. The American Journal of Psychiatry. 167: 388-96. PMID 19917593 DOI: 10.1176/appi.ajp.2009.08121873  1
2010 Shi L, Srdanovic M, Beuming T, Skrabanek L, Javitch JA, Weinstein H. TRAC - A platform for structure-function studies of NSS-proteins integrates information from bioinformatics and biomedical literature 10th Ieee International Conference On Bioinformatics and Bioengineering 2010, Bibe 2010. 267-272. DOI: 10.1109/BIBE.2010.51  1
2010 Liapakis G, Javitch JA. Substituted Cysteine Accessibility Method (SCAM) G Protein-Coupled Receptors: Essential Methods. 229-250. DOI: 10.1002/9780470749210.ch12  1
2009 Namkung Y, Dipace C, Urizar E, Javitch JA, Sibley DR. G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation. The Journal of Biological Chemistry. 284: 34103-15. PMID 19815545 DOI: 10.1074/jbc.M109.055707  1
2009 Sohy D, Yano H, de Nadai P, Urizar E, Guillabert A, Javitch JA, Parmentier M, Springael JY. Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists. The Journal of Biological Chemistry. 284: 31270-9. PMID 19758998 DOI: 10.1074/jbc.M109.054809  1
2009 Gaskill PJ, Calderon TM, Luers AJ, Eugenin EA, Javitch JA, Berman JW. Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse. The American Journal of Pathology. 175: 1148-59. PMID 19661443 DOI: 10.2353/ajpath.2009.081067  1
2009 Han Y, Moreira IS, Urizar E, Weinstein H, Javitch JA. Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation. Nature Chemical Biology. 5: 688-95. PMID 19648932 DOI: 10.1038/nchembio.199  1
2009 Fontana AC, Sonders MS, Pereira-Junior OS, Knight M, Javitch JA, Rodrigues V, Amara SG, Mortensen OV. Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin. European Journal of Pharmacology. 616: 48-57. PMID 19549517 DOI: 10.1016/j.ejphar.2009.06.023  1
2009 Cui M, Aras R, Christian WV, Rappold PM, Hatwar M, Panza J, Jackson-Lewis V, Javitch JA, Ballatori N, Przedborski S, Tieu K. The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 8043-8. PMID 19416912 DOI: 10.1073/pnas.0900358106  1
2009 Namkung Y, Dipace C, Javitch JA, Sibley DR. G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor. The Journal of Biological Chemistry. 284: 15038-51. PMID 19332542 DOI: 10.1074/jbc.M900388200  1
2009 Quick M, Winther AM, Shi L, Nissen P, Weinstein H, Javitch JA. Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation. Proceedings of the National Academy of Sciences of the United States of America. 106: 5563-8. PMID 19307590 DOI: 10.1073/pnas.0811322106  1
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/nchembio0309-131  1
2009 Guptaroy B, Zhang M, Bowton E, Binda F, Shi L, Weinstein H, Galli A, Javitch JA, Neubig RR, Gnegy ME. A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation. Molecular Pharmacology. 75: 514-24. PMID 19098122 DOI: 10.1124/mol.108.048744  1
2009 Goodwin JS, Larson GA, Swant J, Sen N, Javitch JA, Zahniser NR, De Felice LJ, Khoshbouei H. Amphetamine and methamphetamine differentially affect dopamine transporters in vitro and in vivo. The Journal of Biological Chemistry. 284: 2978-89. PMID 19047053 DOI: 10.1074/jbc.M805298200  1
2009 Lieberman JA, Javitch JA, Moore H. Drs. Lieberman, Javitch, and Moore reply American Journal of Psychiatry. 166: 111-113. DOI: 10.1176/appi.ajp.2008.08091352r  1
2008 Lieberman JA, Javitch JA, Moore H. Cholinergic agonists as novel treatments for schizophrenia: the promise of rational drug development for psychiatry. The American Journal of Psychiatry. 165: 931-6. PMID 18676593 DOI: 10.1176/appi.ajp.2008.08050769  1
2008 Guo W, Urizar E, Kralikova M, Mobarec JC, Shi L, Filizola M, Javitch JA. Dopamine D2 receptors form higher order oligomers at physiological expression levels. The Embo Journal. 27: 2293-304. PMID 18668123 DOI: 10.1038/emboj.2008.153  1
2008 Binda F, Dipace C, Bowton E, Robertson SD, Lute BJ, Fog JU, Zhang M, Sen N, Colbran RJ, Gnegy ME, Gether U, Javitch JA, Erreger K, Galli A. Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux. Molecular Pharmacology. 74: 1101-8. PMID 18617632 DOI: 10.1124/mol.108.048447  1
2008 Shi L, Quick M, Zhao Y, Weinstein H, Javitch JA. The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site. Molecular Cell. 30: 667-77. PMID 18570870 DOI: 10.1016/j.molcel.2008.05.008  1
2008 Beuming T, Kniazeff J, Bergmann ML, Shi L, Gracia L, Raniszewska K, Newman AH, Javitch JA, Weinstein H, Gether U, Loland CJ. The binding sites for cocaine and dopamine in the dopamine transporter overlap. Nature Neuroscience. 11: 780-9. PMID 18568020 DOI: 10.1038/nn.2146  1
2008 Lute BJ, Khoshbouei H, Saunders C, Sen N, Lin RZ, Javitch JA, Galli A. PI3K signaling supports amphetamine-induced dopamine efflux. Biochemical and Biophysical Research Communications. 372: 656-61. PMID 18510945 DOI: 10.1016/j.bbrc.2008.05.091  1
2008 Klewe IV, Nielsen SM, Tarpø L, Urizar E, Dipace C, Javitch JA, Gether U, Egebjerg J, Christensen KV. Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling. Neuropharmacology. 54: 1215-22. PMID 18455202 DOI: 10.1016/j.neuropharm.2008.03.015  1
2008 Kniazeff J, Shi L, Loland CJ, Javitch JA, Weinstein H, Gether U. An intracellular interaction network regulates conformational transitions in the dopamine transporter. The Journal of Biological Chemistry. 283: 17691-701. PMID 18426798 DOI: 10.1074/jbc.M800475200  1
2008 Girgis RR, Javitch JA, Lieberman JA. Antipsychotic drug mechanisms: links between therapeutic effects, metabolic side effects and the insulin signaling pathway. Molecular Psychiatry. 13: 918-29. PMID 18414407 DOI: 10.1038/mp.2008.40  1
2008 Erreger K, Grewer C, Javitch JA, Galli A. Currents in response to rapid concentration jumps of amphetamine uncover novel aspects of human dopamine transporter function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 976-89. PMID 18216205 DOI: 10.1523/JNEUROSCI.2796-07.2008  1
2007 Zapata A, Kivell B, Han Y, Javitch JA, Bolan EA, Kuraguntla D, Jaligam V, Oz M, Jayanthi LD, Samuvel DJ, Ramamoorthy S, Shippenberg TS. Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. The Journal of Biological Chemistry. 282: 35842-54. PMID 17923483 DOI: 10.1074/jbc.M611758200  1
2007 Zomot E, Bendahan A, Quick M, Zhao Y, Javitch JA, Kanner BI. Mechanism of chloride interaction with neurotransmitter:sodium symporters. Nature. 449: 726-30. PMID 17704762 DOI: 10.1038/nature06133  1
2007 Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. Bmc Bioinformatics. 8: 177. PMID 17537266 DOI: 10.1186/1471-2105-8-177  1
2007 Quick M, Javitch JA. Monitoring the function of membrane transport proteins in detergent-solubilized form. Proceedings of the National Academy of Sciences of the United States of America. 104: 3603-8. PMID 17360689 DOI: 10.1073/pnas.0609573104  1
2007 Pin JP, Neubig R, Bouvier M, Devi L, Filizola M, Javitch JA, Lohse MJ, Milligan G, Palczewski K, Parmentier M, Spedding M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacological Reviews. 59: 5-13. PMID 17329545 DOI: 10.1124/pr.59.1.5  1
2007 Bolan EA, Kivell B, Jaligam V, Oz M, Jayanthi LD, Han Y, Sen N, Urizar E, Gomes I, Devi LA, Ramamoorthy S, Javitch JA, Zapata A, Shippenberg TS. D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Molecular Pharmacology. 71: 1222-32. PMID 17267664 DOI: 10.1124/mol.106.027763  1
2007 Wei Y, Williams JM, Dipace C, Sung U, Javitch JA, Galli A, Saunders C. Dopamine transporter activity mediates amphetamine-induced inhibition of Akt through a Ca2+/calmodulin-dependent kinase II-dependent mechanism. Molecular Pharmacology. 71: 835-42. PMID 17164407 DOI: 10.1124/mol.106.026351  1
2007 Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, Mailman RB. Functional selectivity and classical concepts of quantitative pharmacology. The Journal of Pharmacology and Experimental Therapeutics. 320: 1-13. PMID 16803859 DOI: 10.1124/jpet.106.104463  1
2007 Guo N, Guo W, Guillin O, Laruelle M, Javitch J, Rayport S. The surface D2-binding profile of the atypical antipsychotic drug amisulpride Journal of Cerebral Blood Flow and Metabolism. 27: PO03-02U.  1
2006 Fog JU, Khoshbouei H, Holy M, Owens WA, Vaegter CB, Sen N, Nikandrova Y, Bowton E, McMahon DG, Colbran RJ, Daws LC, Sitte HH, Javitch JA, Galli A, Gether U. Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport. Neuron. 51: 417-29. PMID 16908408 DOI: 10.1016/j.neuron.2006.06.028  1
2006 Beuming T, Shi L, Javitch JA, Weinstein H. A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function. Molecular Pharmacology. 70: 1630-42. PMID 16880288 DOI: 10.1124/mol.106.026120  1
2006 Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum. The Journal of Biological Chemistry. 281: 26444-54. PMID 16798738 DOI: 10.1074/jbc.M602438200  1
2006 Shi L, Javitch JA. A role for information collection, management, and integration in structure-function studies of G-protein coupled receptors. Current Pharmaceutical Design. 12: 1771-83. PMID 16712487 DOI: 10.2174/138161206776873707  1
2006 Kahlig KM, Lute BJ, Wei Y, Loland CJ, Gether U, Javitch JA, Galli A. Regulation of dopamine transporter trafficking by intracellular amphetamine. Molecular Pharmacology. 70: 542-8. PMID 16684900 DOI: 10.1124/mol.106.023952  1
2005 Guo W, Shi L, Filizola M, Weinstein H, Javitch JA. Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation. Proceedings of the National Academy of Sciences of the United States of America. 102: 17495-500. PMID 16301531 DOI: 10.1073/pnas.0508950102  1
2005 Sen N, Shi L, Beuming T, Weinstein H, Javitch JA. A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding. Neuropharmacology. 49: 780-90. PMID 16216288 DOI: 10.1016/j.neuropharm.2005.08.014  1
2005 Kniazeff J, Loland CJ, Goldberg N, Quick M, Das S, Sitte HH, Javitch JA, Gether U. Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8. Neuropharmacology. 49: 715-23. PMID 16129457 DOI: 10.1016/j.neuropharm.2005.07.003  1
2005 Sonders MS, Quick M, Javitch JA. How did the neurotransmitter cross the bilayer? A closer view. Current Opinion in Neurobiology. 15: 296-304. PMID 15919190 DOI: 10.1016/j.conb.2005.05.009  1
2005 Garcia BG, Wei Y, Moron JA, Lin RZ, Javitch JA, Galli A. Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution. Molecular Pharmacology. 68: 102-9. PMID 15795321 DOI: 10.1124/mol.104.009092  1
2005 Kahlig KM, Binda F, Khoshbouei H, Blakely RD, McMahon DG, Javitch JA, Galli A. Amphetamine induces dopamine efflux through a dopamine transporter channel. Proceedings of the National Academy of Sciences of the United States of America. 102: 3495-500. PMID 15728379 DOI: 10.1073/pnas.0407737102  1
2004 Javitch JA. The ants go marching two by two: oligomeric structure of G-protein-coupled receptors. Molecular Pharmacology. 66: 1077-82. PMID 15319448 DOI: 10.1124/mol.104.006320  1
2004 Bjerggaard C, Fog JU, Hastrup H, Madsen K, Loland CJ, Javitch JA, Gether U. Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7024-36. PMID 15295038 DOI: 10.1523/JNEUROSCI.1863-04.2004  1
2004 Gnegy ME, Khoshbouei H, Berg KA, Javitch JA, Clarke WP, Zhang M, Galli A. Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter. Molecular Pharmacology. 66: 137-43. PMID 15213305 DOI: 10.1124/mol.66.1.137  1
2004 Liapakis G, Chan WC, Papadokostaki M, Javitch JA. Synergistic contributions of the functional groups of epinephrine to its affinity and efficacy at the beta2 adrenergic receptor. Molecular Pharmacology. 65: 1181-90. PMID 15102946 DOI: 10.1124/mol.65.5.1181  1
2004 Javitch JA. Finding needles in haystacks. Nature Biotechnology. 22: 394-6. PMID 15060551 DOI: 10.1038/nbt0404-394  1
2004 Khoshbouei H, Sen N, Guptaroy B, Johnson L', Lund D, Gnegy ME, Galli A, Javitch JA. N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux. Plos Biology. 2: E78. PMID 15024426 DOI: 10.1371/journal.pbio.0020078  1
2004 Sitte HH, Farhan H, Javitch JA. Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking. Molecular Interventions. 4: 38-47. PMID 14993475 DOI: 10.1124/mi.4.1.38  1
2004 Shi L, Javitch JA. The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice. Proceedings of the National Academy of Sciences of the United States of America. 101: 440-5. PMID 14704269 DOI: 10.1073/pnas.2237265100  1
2004 Kahlig KM, Javitch JA, Galli A. Amphetamine regulation of dopamine transport. Combined measurements of transporter currents and transporter imaging support the endocytosis of an active carrier. The Journal of Biological Chemistry. 279: 8966-75. PMID 14699142 DOI: 10.1074/jbc.M303976200  1
2004 Loland CJ, GrÃ¥näs C, Javitch JA, Gether U. Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding. The Journal of Biological Chemistry. 279: 3228-38. PMID 14597628 DOI: 10.1074/jbc.M304755200  1
2003 Goldberg NR, Beuming T, Soyer OS, Goldstein RA, Weinstein H, Javitch JA. Probing conformational changes in neurotransmitter transporters: a structural context. European Journal of Pharmacology. 479: 3-12. PMID 14612133 DOI: 10.1016/j.ejphar.2003.08.052  1
2003 Hastrup H, Sen N, Javitch JA. The human dopamine transporter forms a tetramer in the plasma membrane: cross-linking of a cysteine in the fourth transmembrane segment is sensitive to cocaine analogs. The Journal of Biological Chemistry. 278: 45045-8. PMID 14519759 DOI: 10.1074/jbc.C300349200  1
2003 Morón JA, Zakharova I, Ferrer JV, Merrill GA, Hope B, Lafer EM, Lin ZC, Wang JB, Javitch JA, Galli A, Shippenberg TS. Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8480-8. PMID 13679416  1
2003 Park S, Geddes TJ, Javitch JA, Kuhn DM. Dopamine prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide: is nitrotyrosine formation an early step in dopamine neuronal damage? The Journal of Biological Chemistry. 278: 28736-42. PMID 12771134 DOI: 10.1074/jbc.M304362200  1
2003 Androutsellis-Theotokis A, Goldberg NR, Ueda K, Beppu T, Beckman ML, Das S, Javitch JA, Rudnick G. Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters. The Journal of Biological Chemistry. 278: 12703-9. PMID 12569103 DOI: 10.1074/jbc.M206563200  1
2003 Khoshbouei H, Wang H, Lechleiter JD, Javitch JA, Galli A. Amphetamine-induced dopamine efflux. A voltage-sensitive and intracellular Na+-dependent mechanism. The Journal of Biological Chemistry. 278: 12070-7. PMID 12556446 DOI: 10.1074/jbc.M212815200  1
2003 Guo W, Shi L, Javitch JA. The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer. The Journal of Biological Chemistry. 278: 4385-8. PMID 12496294 DOI: 10.1074/jbc.C200679200  1
2003 Granas C, Ferrer J, Loland CJ, Javitch JA, Gether U. N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization. The Journal of Biological Chemistry. 278: 4990-5000. PMID 12464618 DOI: 10.1074/jbc.M205058200  1
2003 Shi L, Javitch JA. The Binding Pocket of G-Protein-Coupled Receptors for Biogenic Amines, Retinal, and Other Ligands Handbook of Cell Signaling. 1: 155-160. DOI: 10.1016/B978-012124546-7/50386-7  1
2002 Shi L, Liapakis G, Xu R, Guarnieri F, Ballesteros JA, Javitch JA. Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch. The Journal of Biological Chemistry. 277: 40989-96. PMID 12167654 DOI: 10.1074/jbc.M206801200  1
2002 Norgaard-Nielsen K, Norregaard L, Hastrup H, Javitch JA, Gether U. Zn(2+) site engineering at the oligomeric interface of the dopamine transporter. Febs Letters. 524: 87-91. PMID 12135746 DOI: 10.1016/S0014-5793(02)03008-9  1
2002 Carvelli L, Morón JA, Kahlig KM, Ferrer JV, Sen N, Lechleiter JD, Leeb-Lundberg LM, Merrill G, Lafer EM, Ballou LM, Shippenberg TS, Javitch JA, Lin RZ, Galli A. PI 3-kinase regulation of dopamine uptake. Journal of Neurochemistry. 81: 859-69. PMID 12065645 DOI: 10.1046/j.1471-4159.2002.00892.x  1
2002 Park SU, Ferrer JV, Javitch JA, Kuhn DM. Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4399-405. PMID 12040046  1
2002 Daws LC, Callaghan PD, Morón JA, Kahlig KM, Shippenberg TS, Javitch JA, Galli A. Cocaine increases dopamine uptake and cell surface expression of dopamine transporters. Biochemical and Biophysical Research Communications. 290: 1545-50. PMID 11820798 DOI: 10.1006/bbrc.2002.6384  1
2002 Shi L, Javitch JA. The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop. Annual Review of Pharmacology and Toxicology. 42: 437-67. PMID 11807179 DOI: 10.1146/annurev.pharmtox.42.091101.144224  1
2002 Javitch JA, Shi L, Liapakis G. Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors. Methods in Enzymology. 343: 137-56. PMID 11665562 DOI: 10.1016/S0076-6879(02)43131-X  1
2002 Liapakis G, Shi L, Xu R, Guarnieri F, Ballesteros JA, Javitch JA. Mutations of Cys2856.47 of the β2 adrenergic receptor modulate the Pro-kink in TM6 and produce constitutive activity Review of Clinical Pharmacology and Pharmacokinetics, International Edition. 16: 85.  1
2001 Liapakis G, Simpson MM, Javitch JA. The substituted-cysteine accessibility method (SCAM) to elucidate membrane protein structure. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.15. PMID 18428478 DOI: 10.1002/0471142301.ns0415s08  1
2001 Shi L, Simpson MM, Ballesteros JA, Javitch JA. The first transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle. Biochemistry. 40: 12339-48. PMID 11591153 DOI: 10.1021/bi011204a  1
2001 Hastrup H, Karlin A, Javitch JA. Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment. Proceedings of the National Academy of Sciences of the United States of America. 98: 10055-60. PMID 11526230 DOI: 10.1073/pnas.181344298  1
2001 Xu W, Li J, Chen C, Huang P, Weinstein H, Javitch JA, Shi L, de Riel JK, Liu-Chen LY. Comparison of the amino acid residues in the sixth transmembrane domains accessible in the binding-site crevices of mu, delta, and kappa opioid receptors. Biochemistry. 40: 8018-29. PMID 11434771 DOI: 10.1021/bi002490d  1
2001 Newman AH, Zou MF, Ferrer JV, Javitch JA. [3H]MFZ 2-12: a novel radioligand for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 11: 1659-61. PMID 11425531 DOI: 10.1016/S0960-894X(01)00271-2  1
2001 Ballesteros JA, Shi L, Javitch JA. Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors. Molecular Pharmacology. 60: 1-19. PMID 11408595  1
2001 Reith ME, Berfield JL, Wang LC, Ferrer JV, Javitch JA. The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter. The Journal of Biological Chemistry. 276: 29012-8. PMID 11395483 DOI: 10.1074/jbc.M011785200  1
2001 Ballesteros JA, Jensen AD, Liapakis G, Rasmussen SG, Shi L, Gether U, Javitch JA. Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6. The Journal of Biological Chemistry. 276: 29171-7. PMID 11375997 DOI: 10.1074/jbc.M103747200  1
2001 Wilson J, Lin H, Fu D, Javitch JA, Strange PG. Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation. Journal of Neurochemistry. 77: 493-504. PMID 11299312 DOI: 10.1046/j.1471-4159.2001.00233.x  1
2001 Whitehead RE, Ferrer JV, Javitch JA, Justice JB. Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter. Journal of Neurochemistry. 76: 1242-51. PMID 11181843 DOI: 10.1046/j.1471-4159.2001.00125.x  1
2000 Xu W, Chen C, Huang P, Li J, de Riel JK, Javitch JA, Liu-Chen LY. The conserved cysteine 7.38 residue is differentially accessible in the binding-site crevices of the mu, delta, and kappa opioid receptors. Biochemistry. 39: 13904-15. PMID 11076532 DOI: 10.1021/bi001099p  1
2000 Javitch JA, Shi L, Simpson MM, Chen J, Chiappa V, Visiers I, Weinstein H, Ballesteros JA. The fourth transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle. Biochemistry. 39: 12190-9. PMID 11015197 DOI: 10.1021/bi001069m  1
2000 Liapakis G, Ballesteros JA, Papachristou S, Chan WC, Chen X, Javitch JA. The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor. The Journal of Biological Chemistry. 275: 37779-88. PMID 10964911 DOI: 10.1074/jbc.M002092200  1
2000 Saunders C, Ferrer JV, Shi L, Chen J, Merrill G, Lamb ME, Leeb-Lundberg LM, Carvelli L, Javitch JA, Galli A. Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism. Proceedings of the National Academy of Sciences of the United States of America. 97: 6850-5. PMID 10823899 DOI: 10.1073/pnas.110035297  1
2000 Chen N, Ferrer JV, Javitch JA, Justice JB. Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter. The Journal of Biological Chemistry. 275: 1608-14. PMID 10636852 DOI: 10.1074/jbc.275.3.1608  1
1999 Simpson MM, Ballesteros JA, Chiappa V, Chen J, Suehiro M, Hartman DS, Godel T, Snyder LA, Sakmar TP, Javitch JA. Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments. Molecular Pharmacology. 56: 1116-26. PMID 10570038  1
1999 Marjamäki A, Frang H, Pihlavisto M, Hoffrén AM, Salminen T, Johnson MS, Kallio J, Javitch JA, Scheinin M. Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor. The Journal of Biological Chemistry. 274: 21867-72. PMID 10419505 DOI: 10.1074/jbc.274.31.21867  1
1999 Javitch JA, Ballesteros JA, Chen J, Chiappa V, Simpson MM. Electrostatic and aromatic microdomains within the binding-site crevice of the D2 receptor: contributions of the second membrane-spanning segment. Biochemistry. 38: 7961-8. PMID 10387039 DOI: 10.1021/bi9905314  1
1999 Rasmussen SG, Jensen AD, Liapakis G, Ghanouni P, Javitch JA, Gether U. Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6. Molecular Pharmacology. 56: 175-84. PMID 10385699  1
1998 Javitch JA. Probing structure of neurotransmitter transporters by substituted-cysteine accessibility method. Methods in Enzymology. 296: 331-46. PMID 9779459 DOI: 10.1016/S0076-6879(98)96025-6  1
1998 Ferrer JV, Javitch JA. Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 9238-43. PMID 9689064 DOI: 10.1073/pnas.95.16.9238  1
1998 Javitch JA, Ballesteros JA, Weinstein H, Chen J. A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice. Biochemistry. 37: 998-1006. PMID 9454590 DOI: 10.1021/bi972241y  1
1998 Javitch JA. Mapping the binding-site crevice of the D2 receptor. Advances in Pharmacology (San Diego, Calif.). 42: 412-5. PMID 9327927 DOI: 10.1016/S1054-3589(08)60776-0  1
1997 Javitch JA, Fu D, Liapakis G, Chen J. Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment. The Journal of Biological Chemistry. 272: 18546-9. PMID 9228019 DOI: 10.1074/jbc.272.30.18546  1
1996 Fu D, Ballesteros JA, Weinstein H, Chen J, Javitch JA. Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice. Biochemistry. 35: 11278-85. PMID 8784181 DOI: 10.1021/bi960928x  1
1996 Javitch JA, Fu D, Chen J. Differentiating dopamine D2 ligands by their sensitivities to modification of the cysteine exposed in the binding-site crevice. Molecular Pharmacology. 49: 692-8. PMID 8609898  1
1995 Javitch JA, Fu D, Chen J. Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice. Biochemistry. 34: 16433-9. PMID 8845371 DOI: 10.1021/bi00050a026  1
1995 Javitch JA, Fu D, Chen J, Karlin A. Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method. Neuron. 14: 825-31. PMID 7718244 DOI: 10.1016/0896-6273(95)90226-0  1
1994 Javitch JA, Kaback J, Li X, Karlin A. Expression and characterization of human dopamine D2 receptor in baculovirus-infected insect cells. Journal of Receptor Research. 14: 99-117. PMID 8182575 DOI: 10.3109/10799899409066999  1
1994 Javitch JA, Li X, Kaback J, Karlin A. A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice. Proceedings of the National Academy of Sciences of the United States of America. 91: 10355-9. PMID 7937955 DOI: 10.1073/pnas.91.22.10355  1
1991 Fallon BA, Javitch JA, Hollander E, Liebowitz MR. Hypochondriasis and obsessive compulsive disorder: overlaps in diagnosis and treatment. The Journal of Clinical Psychiatry. 52: 457-60. PMID 1744062  1
1985 Javitch JA, Strittmatter SM, Snyder SH. Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 1513-21. PMID 4009243  1
1985 Javitch JA, D'Amato RJ, Strittmatter SM, Snyder SH. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proceedings of the National Academy of Sciences of the United States of America. 82: 2173-7. PMID 3872460  1
1985 Uhl GR, Javitch JA, Snyder SH. Normal MPTP binding in parkinsonian substantial nigra: evidence for extraneuronal toxin conversion in human brain. Lancet. 1: 956-7. PMID 2859415  1
1984 Javitch JA, Uhl GR, Snyder SH. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: characterization and localization of receptor binding sites in rat and human brain. Proceedings of the National Academy of Sciences of the United States of America. 81: 4591-5. PMID 6611553  1
1984 Javitch JA, Snyder SH. Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP. European Journal of Pharmacology. 106: 455-6. PMID 6335692 DOI: 10.1016/0014-2999(84)90740-4  1
1984 Strittmatter SM, Lo MM, Javitch JA, Snyder SH. Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway. Proceedings of the National Academy of Sciences of the United States of America. 81: 1599-603. PMID 6324207  1
1984 Javitch JA, Blaustein RO, Snyder SH. [3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites. Molecular Pharmacology. 26: 35-44. PMID 6087116  1
1983 Javitch JA, Blaustein RO, Snyder SH. [3H]mazindol binding associated with neuronal dopamine uptake sites in corpus striatum membranes. European Journal of Pharmacology. 90: 461-2. PMID 6884434 DOI: 10.1016/0014-2999(83)90574-5  1
1983 Lee CM, Javitch JA, Snyder SH. Recognition sites for norepinephrine uptake: regulation by neurotransmitter. Science (New York, N.Y.). 220: 626-9. PMID 6301013  1
1983 Lee CM, Javitch JA, Snyder SH. 3h-substance P binding to salivary gland membranes. Regulation by guanyl nucleotides and divalent cations. Molecular Pharmacology. 23: 563-9. PMID 6191191  1
1982 Lee CM, Javitch JA, Snyder SH. Characterization of [3H]desipramine binding associated with neuronal norepinephrine uptake sites in rat brain membranes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 1515-25. PMID 7119871  1
Show low-probability matches.