Howard Y. Chang - Publications

Affiliations: 
2014- Dermatology Stanford University, Palo Alto, CA 

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Year Citation  Score
2024 Wang G, Lee-Yow Y, Chang HY. Approaches to probe and perturb long noncoding RNA functions in diseases. Current Opinion in Genetics & Development. 85: 102158. PMID 38412563 DOI: 10.1016/j.gde.2024.102158  0.329
2024 Zhu K, Jones MG, Luebeck J, Bu X, Yi H, Hung KL, Wong IT, Zhang S, Mischel PS, Chang HY, Bafna V. CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing. Biorxiv : the Preprint Server For Biology. PMID 38405779 DOI: 10.1101/2024.02.15.580594  0.767
2023 Rose JC, Wong IT, Daniel B, Jones MG, Yost KE, Hung KL, Curtis EJ, Mischel PS, Chang HY. Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair. Biorxiv : the Preprint Server For Biology. PMID 37961138 DOI: 10.1101/2023.10.22.563489  0.748
2023 Chapman OS, Luebeck J, Sridhar S, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, Pagadala MS, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, ... ... Chang HY, et al. Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nature Genetics. PMID 37945900 DOI: 10.1038/s41588-023-01551-3  0.754
2023 Yu M, Nie Y, Yang J, Yang S, Li R, Rao V, Hu X, Fang C, Li S, Song D, Guo F, Snyder MP, Chang HY, Kuo CJ, Xu J, et al. Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease. Cell Reports. 42: 113392. PMID 37925638 DOI: 10.1016/j.celrep.2023.113392  0.406
2023 Li Z, Amaya L, Pi R, Wang SK, Ranjan A, Waymouth RM, Blish CA, Chang HY, Wender PA. Charge-altering releasable transporters enhance mRNA delivery in vitro and exhibit in vivo tropism. Nature Communications. 14: 6983. PMID 37914693 DOI: 10.1038/s41467-023-42672-x  0.626
2023 Berson E, Sreenivas A, Phongpreecha T, Perna A, Grandi FC, Xue L, Ravindra NG, Payrovnaziri N, Mataraso S, Kim Y, Espinosa C, Chang AL, Becker M, Montine KS, Fox EJ, ... Chang HY, et al. Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature. Nature Communications. 14: 4947. PMID 37587197 DOI: 10.1038/s41467-023-40611-4  0.767
2023 Hung KL, Jones MG, Wong IT, Lange JT, Luebeck J, Scanu E, He BJ, Brückner L, Li R, González RC, Schmargon R, Dörr JR, Belk JA, Bafna V, Werner B, ... ... Chang HY, et al. Coordinated inheritance of extrachromosomal DNA species in human cancer cells. Biorxiv : the Preprint Server For Biology. PMID 37503111 DOI: 10.1101/2023.07.18.549597  0.779
2023 Chamorro González R, Conrad T, Stöber MC, Xu R, Giurgiu M, Rodriguez-Fos E, Kasack K, Brückner L, van Leen E, Helmsauer K, Dorado Garcia H, Stefanova ME, Hung KL, Bei Y, Schmelz K, ... ... Chang HY, et al. Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature Genetics. 55: 880-890. PMID 37142849 DOI: 10.1038/s41588-023-01386-y  0.798
2023 Gonzalez-Sandoval A, Pekrun K, Tsuji S, Zhang F, Hung KL, Chang HY, Kay MA. The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner. Nature Communications. 14: 2448. PMID 37117181 DOI: 10.1038/s41467-023-38106-3  0.772
2023 Chang HY, Qi LS. Reversing the Central Dogma: RNA-guided control of DNA in epigenetics and genome editing. Molecular Cell. 83: 442-451. PMID 36736311 DOI: 10.1016/j.molcel.2023.01.010  0.324
2023 Chen LL, Bindereif A, Bozzoni I, Chang HY, Matera AG, Gorospe M, Hansen TB, Kjems J, Ma XK, Pek JW, Rajewsky N, Salzman J, Wilusz JE, Yang L, Zhao F. A guide to naming eukaryotic circular RNAs. Nature Cell Biology. PMID 36658223 DOI: 10.1038/s41556-022-01066-9  0.586
2023 Mattick JS, Amaral PP, Carninci P, Carpenter S, Chang HY, Chen LL, Chen R, Dean C, Dinger ME, Fitzgerald KA, Gingeras TR, Guttman M, Hirose T, Huarte M, Johnson R, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews. Molecular Cell Biology. PMID 36596869 DOI: 10.1038/s41580-022-00566-8  0.752
2022 Haddad Derafshi B, Danko T, Chanda S, Batista PJ, Litzenburger U, Lee QY, Ng YH, Sebin A, Chang HY, Südhof TC, Wernig M. The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1. Scientific Reports. 12: 22425. PMID 36575212 DOI: 10.1038/s41598-022-23614-x  0.682
2022 Wang SK, Nair S, Li R, Kraft K, Pampari A, Patel A, Kang JB, Luong C, Kundaje A, Chang HY. Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases. Cell Genomics. 2. PMID 36277849 DOI: 10.1016/j.xgen.2022.100164  0.741
2022 Hung KL, Luebeck J, Dehkordi SR, Colón CI, Li R, Wong IT, Coruh C, Dharanipragada P, Lomeli SH, Weiser NE, Moriceau G, Zhang X, Bailey C, Houlahan KE, Yang W, ... ... Chang HY, et al. Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH. Nature Genetics. PMID 36253572 DOI: 10.1038/s41588-022-01190-0  0.765
2022 Lange JT, Rose JC, Chen CY, Pichugin Y, Xie L, Tang J, Hung KL, Yost KE, Shi Q, Erb ML, Rajkumar U, Wu S, Taschner-Mandl S, Bernkopf M, Swanton C, ... ... Chang HY, et al. The evolutionary dynamics of extrachromosomal DNA in human cancers. Nature Genetics. PMID 36123406 DOI: 10.1038/s41588-022-01177-x  0.764
2022 Moonen JR, Chappell J, Shi M, Shinohara T, Li D, Mumbach MR, Zhang F, Nair RV, Nasser J, Mai DH, Taylor S, Wang L, Metzger RJ, Chang HY, Engreitz JM, et al. KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress. Nature Communications. 13: 4941. PMID 35999210 DOI: 10.1038/s41467-022-32566-9  0.4
2022 Chen R, Wang SK, Belk JA, Amaya L, Li Z, Cardenas A, Abe BT, Chen CK, Wender PA, Chang HY. Author Correction: Engineering circular RNA for enhanced protein production. Nature Biotechnology. PMID 35978134 DOI: 10.1038/s41587-022-01472-2  0.654
2022 Hung KL, Mischel PS, Chang HY. Gene regulation on extrachromosomal DNA. Nature Structural & Molecular Biology. 29: 736-744. PMID 35948767 DOI: 10.1038/s41594-022-00806-7  0.78
2022 Chen R, Wang SK, Belk JA, Amaya L, Li Z, Cardenas A, Abe BT, Chen CK, Wender PA, Chang HY. Engineering circular RNA for enhanced protein production. Nature Biotechnology. PMID 35851375 DOI: 10.1038/s41587-022-01393-0  0.7
2022 Kraft K, Yost KE, Murphy SE, Magg A, Long Y, Corces MR, Granja JM, Wittler L, Mundlos S, Cech TR, Boettiger AN, Chang HY. Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201883119. PMID 35617427 DOI: 10.1073/pnas.2201883119  0.675
2022 Raj N, Wang M, Seoane JA, Zhao RL, Kaiser AM, Moonie NA, Demeter J, Boutelle AM, Kerr CH, Mulligan AS, Moffatt C, Zeng SX, Lu H, Barna M, Curtis C, ... Chang HY, et al. The Mettl3 epitranscriptomic writer amplifies p53 stress responses. Molecular Cell. PMID 35512709 DOI: 10.1016/j.molcel.2022.04.010  0.501
2022 Xie L, Dong P, Qi Y, Hsieh TS, English BP, Jung S, Chen X, De Marzio M, Casellas R, Chang HY, Zhang B, Tjian R, Liu Z. BRD2 compartmentalizes the accessible genome. Nature Genetics. 54: 481-491. PMID 35410381 DOI: 10.1038/s41588-022-01044-9  0.681
2022 Weiser NE, Hung KL, Chang HY. Oncogene Convergence in Extrachromosomal DNA Hubs. Cancer Discovery. 12: 1195-1198. PMID 35398879 DOI: 10.1158/2159-8290.CD-22-0076  0.751
2022 Bailey AS, Batista PJ, Chang HY, Fuller MT. Identification of Protein-RNA Interactions in Mouse Testis Tissue Using fRIP. Bio-Protocol. 12: e4286. PMID 35118177 DOI: 10.21769/BioProtoc.4286  0.718
2022 Meijer M, Agirre E, Kabbe M, van Tuijn CA, Heskol A, Zheng C, Mendanha Falcão A, Bartosovic M, Kirby L, Calini D, Johnson MR, Corces MR, Montine TJ, Chen X, Chang HY, et al. Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility. Neuron. PMID 35093191 DOI: 10.1016/j.neuron.2021.12.034  0.709
2021 Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro González R, Weiser NE, Chen C, Valieva ME, Wong IT, Wu S, Dehkordi SR, ... ... Chang HY, et al. ecDNA hubs drive cooperative intermolecular oncogene expression. Nature. PMID 34819668 DOI: 10.1038/s41586-021-04116-8  0.81
2021 Cable J, Heard E, Hirose T, Prasanth KV, Chen LL, Henninger JE, Quinodoz SA, Spector DL, Diermeier SD, Porman AM, Kumar D, Feinberg MW, Shen X, Unfried JP, Johnson R, ... ... Chang HY, et al. Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34791665 DOI: 10.1111/nyas.14713  0.612
2021 Richards RM, Zhao F, Freitas KA, Parker KR, Xu P, Fan A, Sotillo E, Daugaard M, Oo HZ, Liu J, Hong WJ, Sorensen PH, Chang HY, Satpathy AT, Majzner RG, et al. NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity. Blood Cancer Discovery. 2: 648-665. PMID 34778803 DOI: 10.1158/2643-3230.BCD-20-0208  0.502
2021 Kim DS, Risca VI, Reynolds DL, Chappell J, Rubin AJ, Jung N, Donohue LKH, Lopez-Pajares V, Kathiria A, Shi M, Zhao Z, Deep H, Sharmin M, Rao D, Lin S, ... Chang HY, et al. The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation. Nature Genetics. PMID 34650237 DOI: 10.1038/s41588-021-00947-3  0.392
2021 Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, Orloff L, Chang HY, Kasowski M, Snyder MP. Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications. 12: 5732. PMID 34593797 DOI: 10.1038/s41467-021-25872-1  0.502
2021 Chen CK, Cheng R, Demeter J, Chen J, Weingarten-Gabbay S, Jiang L, Snyder MP, Weissman JS, Segal E, Jackson PK, Chang HY. Structured elements drive extensive circular RNA translation. Molecular Cell. PMID 34437836 DOI: 10.1016/j.molcel.2021.07.042  0.643
2021 Chen L, Chang HY, Artandi SE. Analysis of RNA conformation in endogenously assembled RNPs by icSHAPE. Star Protocols. 2: 100477. PMID 33997809 DOI: 10.1016/j.xpro.2021.100477  0.316
2021 Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, et al. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. PMID 33838111 DOI: 10.1016/j.cell.2021.03.025  0.795
2021 Yu B, Qi Y, Li R, Shi Q, Satpathy AT, Chang HY. B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells. Cell. PMID 33735607 DOI: 10.1016/j.cell.2021.02.015  0.302
2020 Lu Z, Guo JK, Wei Y, Dou DR, Zarnegar B, Ma Q, Li R, Zhao Y, Liu F, Choudhry H, Khavari PA, Chang HY. Structural modularity of the XIST ribonucleoprotein complex. Nature Communications. 11: 6163. PMID 33268787 DOI: 10.1038/s41467-020-20040-3  0.522
2020 Corley M, Flynn RA, Lee B, Blue SM, Chang HY, Yeo GW. Footprinting SHAPE-eCLIP Reveals Transcriptome-wide Hydrogen Bonds at RNA-Protein Interfaces. Molecular Cell. PMID 33242392 DOI: 10.1016/j.molcel.2020.11.014  0.33
2020 Corces MR, Shcherbina A, Kundu S, Gloudemans MJ, Frésard L, Granja JM, Louie BH, Eulalio T, Shams S, Bagdatli ST, Mumbach MR, Liu B, Montine KS, Greenleaf WJ, Kundaje A, ... ... Chang HY, et al. Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer's and Parkinson's diseases. Nature Genetics. PMID 33106633 DOI: 10.1038/s41588-020-00721-x  0.405
2020 Parker KR, Migliorini D, Perkey E, Yost KE, Bhaduri A, Bagga P, Haris M, Wilson NE, Liu F, Gabunia K, Scholler J, Montine TJ, Bhoj VG, Reddy R, Mohan S, ... ... Chang HY, et al. Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies. Cell. PMID 32961131 DOI: 10.1016/J.Cell.2020.08.022  0.479
2020 Kim H, Nguyen NP, Turner K, Wu S, Gujar AD, Luebeck J, Liu J, Deshpande V, Rajkumar U, Namburi S, Amin SB, Yi E, Menghi F, Schulte JH, Henssen AG, ... Chang HY, et al. Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. Nature Genetics. PMID 32807987 DOI: 10.1038/S41588-020-0678-2  0.334
2020 Wilson KD, Ameen M, Guo H, Abilez OJ, Tian L, Mumbach MR, Diecke S, Qin X, Liu Y, Yang H, Ma N, Gaddam S, Cunningham NJ, Gu M, Neofytou E, ... ... Chang HY, et al. Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates. Developmental Cell. PMID 32763147 DOI: 10.1016/J.Devcel.2020.07.006  0.415
2020 Ramilowski JA, Yip CW, Agrawal S, Chang JC, Ciani Y, Kulakovskiy IV, Mendez M, Ooi JLC, Ouyang JF, Parkinson N, Petri A, Roos L, Severin J, Yasuzawa K, Abugessaisa I, ... ... Chang H, et al. Functional annotation of human long noncoding RNAs via molecular phenotyping. Genome Research. PMID 32718982 DOI: 10.1101/Gr.254219.119  0.466
2020 Wu KE, Fazal FM, Parker KR, Zou J, Chang HY. RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus. Cell Systems. PMID 32673562 DOI: 10.1016/J.Cels.2020.06.008  0.799
2020 Rinn JL, Chang HY. Long Noncoding RNAs: Molecular Modalities to Organismal Functions. Annual Review of Biochemistry. 89: 283-308. PMID 32569523 DOI: 10.1146/Annurev-Biochem-062917-012708  0.648
2020 Ang CE, Trevino AE, Chang HY. Diverse lncRNA mechanisms in brain development and disease. Current Opinion in Genetics & Development. 65: 42-46. PMID 32554106 DOI: 10.1016/J.Gde.2020.05.006  0.451
2020 Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, ... ... Chang HY, et al. A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by T cells. Nature. PMID 32499651 DOI: 10.1038/S41586-020-2296-7  0.35
2020 Fazal FM, Chang HY. Subcellular Spatial Transcriptomes: Emerging Frontier for Understanding Gene Regulation. Cold Spring Harbor Symposia On Quantitative Biology. PMID 32482897 DOI: 10.1101/Sqb.2019.84.040352  0.819
2020 Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho SW, Mistry A, ... ... Chang HY, et al. Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. Elife. 9. PMID 32379046 DOI: 10.7554/Elife.54508  0.453
2020 Paik DT, Cho S, Tian L, Chang HY, Wu JC. Single-cell RNA sequencing in cardiovascular development, disease and medicine. Nature Reviews. Cardiology. PMID 32231331 DOI: 10.1038/S41569-020-0359-Y  0.379
2020 Lee QY, Mall M, Chanda S, Zhou B, Sharma KS, Schaukowitch K, Adrian-Segarra JM, Grieder SD, Kareta MS, Wapinski OL, Ang CE, Li R, Südhof TC, Chang HY, Wernig M. Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes. Nature Cell Biology. PMID 32231311 DOI: 10.1038/S41556-020-0490-3  0.312
2020 Wu KE, Parker KR, Fazal FM, Chang H, Zou J. RNA-GPS predicts high-resolution RNA subcellular localization and highlights the role of splicing. Rna (New York, N.Y.). PMID 32220894 DOI: 10.1261/Rna.074161.119  0.803
2020 Xie L, Dong P, Chen X, Hsieh TS, Banala S, De Marzio M, English BP, Qi Y, Jung SK, Kieffer-Kwon KR, Legant WR, Hansen AS, Schulmann A, Casellas R, Zhang B, ... ... Chang HY, et al. 3D ATAC-PALM: super-resolution imaging of the accessible genome. Nature Methods. PMID 32203384 DOI: 10.1038/S41592-020-0775-2  0.708
2020 Horlbeck MA, Liu SJ, Chang HY, Lim DA, Weissman JS. Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes. Nature Biotechnology. PMID 32094656 DOI: 10.1038/S41587-020-0428-0  0.411
2020 Wasson CW, Abignano G, Hermes H, Malaab M, Ross RL, Jimenez SA, Chang HY, Feghali-Bostwick CA, Del Galdo F. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Annals of the Rheumatic Diseases. PMID 32041748 DOI: 10.1136/Annrheumdis-2019-216542  0.32
2020 Li Y, Gruber JJ, Litzenburger UM, Zhou Y, Miao YR, LaGory EL, Li AM, Hu Z, Yip M, Hart LS, Maris JM, Chang HY, Giaccia AJ, Ye J. Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. Cell Death & Disease. 11: 102. PMID 32029721 DOI: 10.1038/S41419-020-2303-9  0.335
2020 Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E, Mangan PA, Kulikovskaya I, Gupta M, Chen F, Tian L, Gonzalez VE, Xu J, Jung IY, Melenhorst JJ, ... ... Chang HY, et al. CRISPR-engineered T cells in patients with refractory cancer. Science (New York, N.Y.). PMID 32029687 DOI: 10.1126/Science.Aba7365  0.341
2020 Trevino AE, Sinnott-Armstrong N, Andersen J, Yoon SJ, Huber N, Pritchard JK, Chang HY, Greenleaf WJ, Pașca SP. Chromatin accessibility dynamics in a model of human forebrain development. Science (New York, N.Y.). 367. PMID 31974223 DOI: 10.1126/Science.Aay1645  0.344
2020 Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho S, Mistry A, ... ... Chang HY, et al. Author response: Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation Elife. DOI: 10.7554/Elife.54508.Sa2  0.355
2020 Chang HY. Abstract PL01-01: Personal regulome navigation of cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Pl01-01  0.367
2020 Ramilowski JA, Yip CW, Agrawal S, Chang J, Ciani Y, Kulakovskiy IV, Mendez M, Ooi JLC, Ouyang JF, Parkinson N, Petri A, Roos L, Severin J, Yasuzawa K, Abugessaisa I, ... ... Chang H, et al. Corrigendum: Functional annotation of human long noncoding RNAs via molecular phenotyping Genome Research. 30: 1377-1-1377-1. DOI: 10.1101/Gr.270330.120  0.409
2019 Fang J, Ma Q, Chu C, Huang B, Li L, Cai P, Batista PJ, Tolentino KEM, Xu J, Li R, Du P, Qu K, Chang HY. PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications. Genome Biology. 20: 292. PMID 31862000 DOI: 10.1186/S13059-019-1880-3  0.734
2019 Yost KE, Chang HY, Satpathy AT. Tracking the immune response with single-cell genomics. Vaccine. PMID 31859202 DOI: 10.1016/J.Vaccine.2019.11.035  0.307
2019 Esfahani MS, Lee LJ, Jeon YJ, Flynn RA, Stehr H, Hui AB, Ishisoko N, Kildebeck E, Newman AM, Bratman SV, Porteus MH, Chang HY, Alizadeh AA, Diehn M. Functional significance of U2AF1 S34F mutations in lung adenocarcinomas. Nature Communications. 10: 5712. PMID 31836708 DOI: 10.1038/S41467-019-13392-Y  0.659
2019 Lynn RC, Weber EW, Sotillo E, Gennert D, Xu P, Good Z, Anbunathan H, Lattin J, Jones R, Tieu V, Nagaraja S, Granja J, de Bourcy CFA, Majzner R, Satpathy AT, ... ... Chang HY, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. PMID 31802004 DOI: 10.1038/S41586-019-1805-Z  0.313
2019 Granja JM, Klemm S, McGinnis LM, Kathiria AS, Mezger A, Corces MR, Parks B, Gars E, Liedtke M, Zheng GXY, Chang HY, Majeti R, Greenleaf WJ. Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia. Nature Biotechnology. PMID 31792411 DOI: 10.1038/S41587-019-0332-7  0.791
2019 Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, ... ... Chang HY, et al. Circular ecDNA promotes accessible chromatin and high oncogene expression. Nature. PMID 31748743 DOI: 10.1038/S41586-019-1763-5  0.735
2019 López-Isac E, Acosta-Herrera M, Kerick M, Assassi S, Satpathy AT, Granja J, Mumbach MR, Beretta L, Simeón CP, Carreira P, Ortego-Centeno N, Castellvi I, Bossini-Castillo L, Carmona FD, Orozco G, ... ... Chang HY, et al. GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways. Nature Communications. 10: 4955. PMID 31672989 DOI: 10.1038/S41467-019-12760-Y  0.304
2019 Chen YG, Chen R, Ahmad S, Verma R, Kasturi SP, Amaya L, Broughton JP, Kim J, Cadena C, Pulendran B, Hur S, Chang HY. N6-Methyladenosine Modification Controls Circular RNA Immunity. Molecular Cell. PMID 31474572 DOI: 10.1016/J.Molcel.2019.07.016  0.371
2019 Bousard A, Raposo AC, Żylicz JJ, Picard C, Pires VB, Qi Y, Gil C, Syx L, Chang HY, Heard E, da Rocha ST. The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation. Embo Reports. e48019. PMID 31456285 DOI: 10.15252/Embr.201948019  0.429
2019 Durai V, Bagadia P, Granja JM, Satpathy AT, Kulkarni DH, Davidson JT, Wu R, Patel SJ, Iwata A, Liu TT, Huang X, Briseño CG, Grajales-Reyes GE, Wöhner M, Tagoh H, ... ... Chang HY, et al. Cryptic activation of an Irf8 enhancer governs cDC1 fate specification. Nature Immunology. PMID 31406378 DOI: 10.1038/S41590-019-0450-X  0.364
2019 Bagadia P, Huang X, Liu TT, Durai V, Grajales-Reyes GE, Nitschké M, Modrusan Z, Granja JM, Satpathy AT, Briseño CG, Gargaro M, Iwata A, Kim S, Chang HY, Shaw AS, et al. An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. Nature Immunology. PMID 31406377 DOI: 10.1038/S41590-019-0449-3  0.39
2019 Satpathy AT, Granja JM, Yost KE, Qi Y, Meschi F, McDermott GP, Olsen BN, Mumbach MR, Pierce SE, Corces MR, Shah P, Bell JC, Jhutty D, Nemec CM, Wang J, ... ... Chang HY, et al. Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion. Nature Biotechnology. 37: 925-936. PMID 31375813 DOI: 10.1038/S41587-019-0206-Z  0.798
2019 Yost KE, Satpathy AT, Wells DK, Qi Y, Wang C, Kageyama R, McNamara KL, Granja JM, Sarin KY, Brown RA, Gupta RK, Curtis C, Bucktrout SL, Davis MM, Chang ALS, ... Chang HY, et al. Clonal replacement of tumor-specific T cells following PD-1 blockade. Nature Medicine. PMID 31359002 DOI: 10.1038/S41591-019-0522-3  0.3
2019 Ghosh RP, Shi Q, Yang L, Reddick MP, Nikitina T, Zhurkin VB, Fordyce P, Stasevich TJ, Chang HY, Greenleaf WJ, Liphardt JT. Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions. Nature Communications. 10: 3221. PMID 31324780 DOI: 10.1038/S41467-019-11118-8  0.307
2019 Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, ... ... Chang HY, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/S41586-019-1406-X  0.712
2019 Fazal FM, Han S, Parker KR, Kaewsapsak P, Xu J, Boettiger AN, Chang HY, Ting AY. Atlas of Subcellular RNA Localization Revealed by APEX-Seq. Cell. PMID 31230715 DOI: 10.1016/J.Cell.2019.05.027  0.808
2019 Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, ... ... Chang HY, et al. HiChIRP reveals RNA-associated chromosome conformation. Nature Methods. PMID 31133759 DOI: 10.1038/S41592-019-0407-X  0.455
2019 Xu J, Nuno K, Litzenburger UM, Qi Y, Corces MR, Majeti R, Chang HY. Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA. Elife. 8. PMID 30958261 DOI: 10.7554/Elife.45105  0.571
2019 Sun L, Fazal FM, Li P, Broughton JP, Lee B, Tang L, Huang W, Kool ET, Chang HY, Zhang QC. RNA structure maps across mammalian cellular compartments. Nature Structural & Molecular Biology. PMID 30886404 DOI: 10.1038/S41594-019-0200-7  0.824
2019 Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/J.Immuni.2018.12.016  0.36
2019 Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, ... ... Chang HY, et al. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment. Cell Stem Cell. PMID 30686763 DOI: 10.1016/J.Stem.2018.12.012  0.347
2019 Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 8. PMID 30644360 DOI: 10.7554/Elife.40197  0.314
2019 Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, ... ... Chang HY, et al. The novel lncRNA is pro-neurogenic and mutated in human neurodevelopmental disorders. Elife. 8. PMID 30628890 DOI: 10.7554/Elife.41770  0.401
2019 Xu J, Nuno K, Litzenburger UM, Qi Y, Corces MR, Majeti R, Chang HY. Author response: Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA Elife. DOI: 10.7554/Elife.45105.033  0.542
2019 Mumbach M, Granja J, Flynn R, Roake C, Satpathy A, Rubin A, Qi Y, Jiang Z, Shams S, Louie B, Guo J, Gennert D, Corces MR, Khavari P, Atianand M, ... ... Chang H, et al. HiChIRP: RNA-centric chromatin conformation Protocol Exchange. DOI: 10.1038/Protex.2019.032  0.406
2019 Ramanathan M, Rubin A, Parker K, Satpathy A, Greenleaf W, Chang H, Khavari P. 366 Unraveling keratinocyte gene regulatory networks with single-cell cripsr screening and epigenomic profiling Journal of Investigative Dermatology. 139: S63. DOI: 10.1016/J.Jid.2019.03.442  0.302
2019 Simonetta F, Maas-Bauer K, Hirai T, Wenokur A, Fazal FM, Kambham N, Ribado J, Mavers M, Baker J, Bhatt AS, Chang HY, Negrin RS. Distinct Immune Regulatory Potential of Invariant Natural Killer T (iNKT) Cell Subsets: iNKT2 and iNKT17, but Not iNKT1, Protect from Graft-Versus-Host-Disease Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.683  0.767
2018 Rubin AJ, Parker KR, Satpathy AT, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY, Khavari PA. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. PMID 30580963 DOI: 10.1016/J.Cell.2018.11.022  0.45
2018 Lu Z, Chang HY. The RNA Base-Pairing Problem and Base-Pairing Solutions. Cold Spring Harbor Perspectives in Biology. 10. PMID 30510063 DOI: 10.1101/Cshperspect.A034926  0.564
2018 Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nature Genetics. PMID 30397335 DOI: 10.1038/S41588-018-0263-0  0.348
2018 Chen X, Litzenburger UM, Wei Y, Schep AN, LaGory EL, Choudhry H, Giaccia AJ, Greenleaf WJ, Chang HY. Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. Nature Communications. 9: 4590. PMID 30389926 DOI: 10.1038/S41467-018-07115-Y  0.715
2018 Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Chang HY, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/Science.Aav1898  0.545
2018 Ransom RC, Carter AC, Salhotra A, Leavitt T, Marecic O, Murphy MP, Lopez ML, Wei Y, Marshall CD, Shen EZ, Jones RE, Sharir A, Klein OD, Chan CKF, Wan DC, ... Chang HY, et al. Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration. Nature. PMID 30356216 DOI: 10.1038/S41586-018-0650-9  0.328
2018 Jeng MY, Mumbach MR, Granja JM, Satpathy AT, Chang HY, Chang ALS. Enhancer connectome nominates target genes of inherited risk variants from inflammatory skin disorders. The Journal of Investigative Dermatology. PMID 30315781 DOI: 10.1016/J.Jid.2018.09.011  0.367
2018 Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, ... ... Chang HY, et al. Identification of the Human Skeletal Stem Cell. Cell. 175: 43-56.e21. PMID 30241615 DOI: 10.1016/J.Cell.2018.07.029  0.577
2018 Chu C, Chang HY. ChIRP-MS: RNA-Directed Proteomic Discovery. Methods in Molecular Biology (Clifton, N.J.). 1861: 37-45. PMID 30218357 DOI: 10.1007/978-1-4939-8766-5_3  0.398
2018 Arda HE, Tsai J, Rosli YR, Giresi P, Bottino R, Greenleaf WJ, Chang HY, Kim SK. A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas. Cell Systems. PMID 30145115 DOI: 10.1016/J.Cels.2018.07.007  0.351
2018 Gate RE, Cheng CS, Aiden AP, Siba A, Tabaka M, Lituiev D, Machol I, Gordon MG, Subramaniam M, Shamim M, Hougen KL, Wortman I, Huang SC, Durand NC, Feng T, ... ... Chang HY, et al. Genetic determinants of co-accessible chromatin regions in activated T cells across humans. Nature Genetics. PMID 29988122 DOI: 10.1038/S41588-018-0156-2  0.381
2018 Duren Z, Chen X, Zamanighomi M, Zeng W, Satpathy AT, Chang HY, Wang Y, Wong WH. Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987051 DOI: 10.1073/Pnas.1805681115  0.347
2018 Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell. PMID 29804836 DOI: 10.1016/J.Cell.2018.04.039  0.721
2018 Satpathy AT, Brown RA, Gomulia E, Briseño CG, Mumbach MR, Pan Z, Murphy KM, Natkunam Y, Chang HY, Kim J. Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 29743654 DOI: 10.1038/S41379-018-0052-4  0.331
2018 Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, ... ... Chang HY, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. PMID 29731168 DOI: 10.1016/J.Cell.2018.03.068  0.406
2018 Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ. Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation. Cell. PMID 29706549 DOI: 10.1016/J.Cell.2018.03.074  0.635
2018 Wang KC, Chang HY. Epigenomics: Technologies and Applications. Circulation Research. 122: 1191-1199. PMID 29700067 DOI: 10.1161/Circresaha.118.310998  0.507
2018 Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, ... ... Chang HY, et al. Transcript-indexed ATAC-seq for precision immune profiling. Nature Medicine. PMID 29686426 DOI: 10.1038/S41591-018-0008-8  0.303
2018 Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. PMID 29364875 DOI: 10.1038/Nature25449  0.426
2018 Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nature Immunology. PMID 29335648 DOI: 10.1038/S41590-017-0032-8  0.334
2018 Maas-Bauer K, Simonetta F, Hirai T, Wenokur A, Fazal F, Kambham N, Ribado J, Mavers M, Baker J, Bhatt AS, Chang HY, Negrin RS. Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential Blood. 132: 475-475. DOI: 10.1182/Blood-2018-99-113673  0.771
2018 Lynn RC, Weber EW, Gennert D, Sotillo E, Jones R, Xu P, Satpathy A, Chang HY, Mackall CL. Abstract LB-112: Engineering AP1 to combat CAR T cell exhaustion Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-112  0.326
2018 Chang HY. Abstract PL05-01: Personal regulome navigation Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-Pl05-01  0.41
2018 Kim D, Risca V, Chappell J, Shi M, Zhao Z, Jung N, Chang H, Snyder M, Greenleaf W, Kundaje A, Khavari P. 795 Decoding regulatory sequence across skin differentiation with deep learning Journal of Investigative Dermatology. 138: S135. DOI: 10.1016/J.Jid.2018.03.805  0.394
2018 Lee MY, Chen X, Gustavsson A, Chang HY, Moerner W. In Situ Imaging of Spatial Organization of Accessible Chromatin at the Nanoscale with ATAC-see and Single-Molecule Super-Resolution Fluorescence Microscopy Biophysical Journal. 114: 539a. DOI: 10.1016/J.Bpj.2017.11.2944  0.657
2017 Chen YG, Chang HY. LncRNA Seduction of GOT2 Goes Viral. Immunity. 47: 1021-1023. PMID 29262346 DOI: 10.1016/J.Immuni.2017.12.006  0.346
2017 Carter AC, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ, Hacohen N, He C, Hill D, Ko J, Kohane I, Kundaje A, et al. Challenges and recommendations for epigenomics in precision health. Nature Biotechnology. 35: 1128-1132. PMID 29220033 DOI: 10.1038/Nbt.4030  0.346
2017 Corces MR, Chang HY, Majeti R. Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia. Frontiers in Oncology. 7: 263. PMID 29164062 DOI: 10.3389/Fonc.2017.00263  0.562
2017 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT. The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 6. PMID 29087293 DOI: 10.7554/Elife.26116  0.736
2017 Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, ... Chang HY, et al. Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons. Cell Reports. 20: 3236-3247. PMID 28954238 DOI: 10.1016/J.Celrep.2017.09.011  0.337
2017 Lu Z, Carter AC, Chang HY. Mechanistic insights in X-chromosome inactivation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28947655 DOI: 10.1098/Rstb.2016.0356  0.525
2017 Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Chang HY, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963  0.378
2017 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Chang HY, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875  0.389
2017 Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, ... ... Chang HY, et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature Methods. PMID 28846090 DOI: 10.1038/Nmeth.4396  0.46
2017 Chen YG, Satpathy AT, Chang HY. Gene regulation in the immune system by long noncoding RNAs. Nature Immunology. 18: 962-972. PMID 28829444 DOI: 10.1038/Ni.3771  0.463
2017 Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, ... ... Chang HY, et al. Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature Genetics. PMID 28805829 DOI: 10.1038/Ng.3935  0.495
2017 Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, ... Chang HY, et al. m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. Nature. PMID 28792938 DOI: 10.1038/Nature23450  0.686
2017 Liu Q, Jiang C, Xu J, Zhao M, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP. Genome-Wide Temporal Profiling of Transcriptome and Open-Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs. Circulation Research. PMID 28663367 DOI: 10.1161/Circresaha.116.310456  0.512
2017 Wang KC, Chang HY. Transcription coactivator and lncRNA duet evoke Hox genes. Plos Genetics. 13: e1006797. PMID 28662057 DOI: 10.1371/Journal.Pgen.1006797  0.557
2017 Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY. Sensing Self and Foreign Circular RNAs by Intron Identity. Molecular Cell. PMID 28625551 DOI: 10.1016/J.Molcel.2017.05.022  0.818
2017 Qu K, Zaba LC, Satpathy AT, Giresi PG, Li R, Jin Y, Armstrong R, Jin C, Schmitt N, Rahbar Z, Ueno H, Greenleaf WJ, Kim YH, Chang HY. Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors. Cancer Cell. PMID 28625481 DOI: 10.1016/J.Ccell.2017.05.008  0.33
2017 Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 169: 1051-1065.e18. PMID 28575669 DOI: 10.1016/J.Cell.2017.05.022  0.384
2017 Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, ... ... Chang HY, et al. Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nature Medicine. PMID 28288111 DOI: 10.1038/Nm.4309  0.395
2017 Schmitt AM, Chang HY. Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. Cold Spring Harbor Perspectives in Medicine. PMID 28193769 DOI: 10.1101/Cshperspect.A026492  0.737
2017 Litzenburger UM, Buenrostro JD, Wu B, Shen Y, Sheffield NC, Kathiria A, Greenleaf WJ, Chang HY. Single-cell epigenomic variability reveals functional cancer heterogeneity. Genome Biology. 18: 15. PMID 28118844 DOI: 10.1186/S13059-016-1133-7  0.319
2017 Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY. Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nature Genetics. PMID 28112738 DOI: 10.1038/Ng.3769  0.368
2017 Bailey AS, Batista PJ, Gold RS, Chen YG, Rooij DGd, Chang HY, Fuller MT. Author response: The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline Elife. DOI: 10.7554/Elife.26116.050  0.718
2017 Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, ... ... Chang HY, et al. Omni-ATAC-seq: Improved ATAC-seq protocol Protocol Exchange. DOI: 10.1038/Protex.2017.096  0.435
2017 Lopez-Pajares V, Rubin A, Barajas B, Furlan-Magaril M, Mumbach M, Greenleaf W, Kundaje A, Snyder M, Chang H, Fraser P, Khavari P. 464 Dynamic and stable enhancer-promoter contacts regulate epidermal terminal differentiation Journal of Investigative Dermatology. 137: S80. DOI: 10.1016/J.Jid.2017.02.483  0.422
2017 Moore AL, Marshall CD, Litzenburger U, Barnes L, Ransom RC, Hu M, Leavitt T, Chang HY, Longaker MT. Epigenetic Analysis of Scar Forming Fibroblasts Reveals Key Differences in Genes Associated with Fibrosis Journal of the American College of Surgeons. 225: S200-S201. DOI: 10.1016/J.Jamcollsurg.2017.07.460  0.318
2016 Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science (New York, N.Y.). PMID 27980086 DOI: 10.1126/Science.Aah7111  0.458
2016 Lee B, Flynn RA, Kadina A, Guo JK, Kool ET, Chang HY. Comparison of SHAPE Reagents for Mapping RNA Structures Inside Living Cells. Rna (New York, N.Y.). PMID 27879433 DOI: 10.1261/Rna.058784.116  0.392
2016 Xu J, Spitale RC, Guan L, Flynn RA, Torre EA, Li R, Raber I, Qu K, Kern D, Knaggs HE, Chang HY, Chang AL. Novel Gene Expression Profile of Women with Intrinsic Skin Youthfulness by Whole Transcriptome Sequencing. Plos One. 11: e0165913. PMID 27829007 DOI: 10.1371/Journal.Pone.0165913  0.615
2016 Chen X, Shen Y, Draper W, Buenrostro JD, Litzenburger U, Cho SW, Satpathy AT, Carter AC, Ghosh RP, East-Seletsky A, Doudna JA, Greenleaf WJ, Liphardt JT, Chang HY. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nature Methods. PMID 27749837 DOI: 10.1038/Nmeth.4031  0.715
2016 Fazal FM, Chang HY. lncRNA Structure: Message to the Heart. Molecular Cell. 64: 1-2. PMID 27716479 DOI: 10.1016/J.Molcel.2016.09.030  0.776
2016 Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nature Genetics. PMID 27668660 DOI: 10.1038/Ng.3673  0.701
2016 Chu C, Chang HY. Understanding RNA-Chromatin Interactions Using Chromatin Isolation by RNA Purification (ChIRP). Methods in Molecular Biology (Clifton, N.J.). 1480: 115-23. PMID 27659979 DOI: 10.1007/978-1-4939-6380-5_10  0.435
2016 Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nature Genetics. PMID 27526324 DOI: 10.1038/Ng.3646  0.673
2016 Wang K, Lee CS, Marinkovich MP, Chang HY, Oro AE, Khavari PA. Factors That May Promote an Effective Local Research Environment. The Journal of Investigative Dermatology. 136: 1529-31. PMID 27450496 DOI: 10.1016/J.Jid.2016.04.015  0.455
2016 Giorgetti L, Lajoie BR, Carter AC, Attia M, Zhan Y, Xu J, Chen CJ, Kaplan N, Chang HY, Heard E, Dekker J. Structural organization of the inactive X chromosome in the mouse. Nature. PMID 27437574 DOI: 10.1038/Nature18589  0.364
2016 Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, et al. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 165: 1672-85. PMID 27315481 DOI: 10.1016/J.Cell.2016.05.075  0.407
2016 Sadik H, Korangath P, Nguyen N, Győrffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Gonzalez Munoz T, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese TL, ... Chang HY, et al. HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells. Cancer Research. PMID 27302171 DOI: 10.1158/0008-5472.Can-16-0774  0.333
2016 Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. PMID 27180905 DOI: 10.1016/J.Cell.2016.04.028  0.708
2016 Arda HE, Li L, Tsai J, Torre EA, Rosli Y, Peiris H, Spitale RC, Dai C, Gu X, Qu K, Wang P, Wang J, Grompe M, Scharfmann R, Snyder MS, ... ... Chang HY, et al. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function. Cell Metabolism. PMID 27133132 DOI: 10.1016/J.Cmet.2016.04.002  0.681
2016 Zarnegar BJ, Flynn RA, Shen Y, Do BT, Chang HY, Khavari PA. irCLIP platform for efficient characterization of protein-RNA interactions. Nature Methods. PMID 27111506 DOI: 10.1038/Nmeth.3840  0.393
2016 Ma Q, Chang HY. Single-cell profiling of lncRNAs in the developing human brain. Genome Biology. 17: 68. PMID 27079200 DOI: 10.1186/S13059-016-0933-0  0.402
2016 Schmitt AM, Chang HY. Long Noncoding RNAs in Cancer Pathways. Cancer Cell. 29: 452-63. PMID 27070700 DOI: 10.1016/J.Ccell.2016.03.010  0.732
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Chang HY, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/J.Molcel.2016.03.013  0.42
2016 Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, ... ... Chang HY, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/Oncotarget.8612  0.429
2016 Lu Z, Chang HY. Decoding the RNA structurome. Current Opinion in Structural Biology. 36: 142-148. PMID 26923056 DOI: 10.1016/J.Sbi.2016.01.007  0.572
2016 He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC. Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart. Circulation. Cardiovascular Genetics. PMID 26896382 DOI: 10.1161/Circgenetics.115.001264  0.411
2016 Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. 7SK-BAF axis controls pervasive transcription at enhancers. Nature Structural & Molecular Biology. PMID 26878240 DOI: 10.1038/Nsmb.3176  0.442
2016 Lee Y, Shin JH, Longmire M, Wang H, Kohrt HE, Chang HY, Sunwoo JB. CD44+ cells in head and neck squamous cell carcinoma suppress T cell-mediated immunity by selective constitutive and inducible expression of PD-L1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26864211 DOI: 10.1158/1078-0432.Ccr-15-2665  0.301
2016 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26789242 DOI: 10.1038/Nature16968  0.309
2016 Quinn JJ, Zhang QC, Georgiev P, Ilik IA, Akhtar A, Chang HY. Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. Genes & Development. 30: 191-207. PMID 26773003 DOI: 10.1101/Gad.272187.115  0.637
2016 Flynn RA, Zhang QC, Spitale RC, Lee B, Mumbach MR, Chang HY. Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Nature Protocols. 11: 273-90. PMID 26766114 DOI: 10.1038/Nprot.2016.011  0.757
2016 Wan Y, Qu K, Ouyang Z, Chang HY. Genome-Wide Probing of RNA Structures In Vitro Using Nucleases and Deep Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1361: 141-60. PMID 26483021 DOI: 10.1007/978-1-4939-3079-1_9  0.655
2016 Chang HY. Abstract IA02: Genome regulation by long noncoding RNAs Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Ia02  0.471
2016 Liu S, Horlbeck M, Cho SW, Birk H, Malatesta M, He D, Villalta J, Cho M, Chen Y, Mandegar M, Olvera M, Conklin B, Chang H, Weissman J, Lim D. GENT-49. SYSTEMATIC IDENTIFICATION OF ESSENTIAL LONG NON-CODING RNA GENES IN GLIOBLASTOMA Neuro-Oncology. 18: vi84-vi85. DOI: 10.1093/Neuonc/Now212.354  0.411
2015 Bao X, Rubin AJ, Qu K, Zhang J, Giresi PG, Chang HY, Khavari PA. A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63. Genome Biology. 16: 284. PMID 26683334 DOI: 10.1186/S13059-015-0840-9  0.333
2015 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo FW, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26675721 DOI: 10.1038/Nature16193  0.452
2015 Quinn JJ, Chang HY. Unique features of long non-coding RNA biogenesis and function. Nature Reviews. Genetics. 17: 47-62. PMID 26666209 DOI: 10.1038/Nrg.2015.10  0.417
2015 Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, ... ... Chang HY, et al. The histone chaperone CAF-1 safeguards somatic cell identity. Nature. 528: 218-224. PMID 26659182 DOI: 10.1038/Nature15749  0.631
2015 Carlson HL, Quinn JJ, Yang YW, Thornburg CK, Chang HY, Stadler HS. LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. Plos Genetics. 11: e1005680. PMID 26633036 DOI: 10.1371/Journal.Pgen.1005680  0.437
2015 Mazumdar C, Shen Y, Xavy S, Zhao F, Reinisch A, Li R, Corces MR, Flynn RA, Buenrostro JD, Chan SM, Thomas D, Koenig JL, Hong WJ, Chang HY, Majeti R. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell. PMID 26607380 DOI: 10.1182/Blood.V126.23.841.841  0.597
2015 Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Erratum: Structural imprints in vivo decode RNA regulatory mechanisms. Nature. PMID 26416736 DOI: 10.1038/Nature15717  0.785
2015 Qu K, Zaba LC, Giresi PG, Li R, Longmire M, Kim YH, Greenleaf WJ, Chang HY. Individuality and variation of personal regulomes in primary human T cells. Cell Systems. 1: 51-61. PMID 26251845 DOI: 10.1016/J.Cels.2015.06.003  0.353
2015 Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Correction to "Structure and Thermodynamics of N(6)-Methyladenosine in RNA: A Spring-Loaded Base Modification". Journal of the American Chemical Society. PMID 26087989 DOI: 10.1021/Jacs.5B05858  0.692
2015 Buenrostro JD, Wu B, Litzenburger UM, Ruff D, Gonzales ML, Snyder MP, Chang HY, Greenleaf WJ. Single-cell chromatin accessibility reveals principles of regulatory variation. Nature. 523: 486-90. PMID 26083756 DOI: 10.1038/Nature14590  0.505
2015 Satpathy AT, Chang HY. Long noncoding RNA in hematopoiesis and immunity. Immunity. 42: 792-804. PMID 25992856 DOI: 10.1016/J.Immuni.2015.05.004  0.472
2015 Grow EJ, Flynn RA, Chavez SL, Bayless NL, Wossidlo M, Wesche DJ, Martin L, Ware CB, Blish CA, Chang HY, Pera RA, Wysocka J. Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells. Nature. 522: 221-5. PMID 25896322 DOI: 10.1038/Nature14308  0.369
2015 Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY. Systematic discovery of Xist RNA binding proteins. Cell. 161: 404-16. PMID 25843628 DOI: 10.1016/J.Cell.2015.03.025  0.641
2015 Chang H, Replogle JM, Vather N, Tsao-Wu M, Mistry R, Liu JM. A cis-regulatory antisense RNA represses translation in Vibrio cholerae through extensive complementarity and proximity to the target locus. Rna Biology. 12: 136-48. PMID 25826566 DOI: 10.1080/15476286.2015.1017203  0.38
2015 Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Structural imprints in vivo decode RNA regulatory mechanisms. Nature. 519: 486-90. PMID 25799993 DOI: 10.1038/Nature14263  0.829
2015 Cho SW, Chang HY. Genomics: CRISPR engineering turns on genes. Nature. 517: 560-2. PMID 25631441 DOI: 10.1038/517560A  0.371
2015 Corley M, Solem A, Qu K, Chang HY, Laederach A. Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark. Nucleic Acids Research. 43: 1859-68. PMID 25618847 DOI: 10.1093/Nar/Gkv010  0.391
2015 Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET. Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification. Journal of the American Chemical Society. 137: 2107-15. PMID 25611135 DOI: 10.1021/Ja513080V  0.712
2015 Chu C, Spitale RC, Chang HY. Technologies to probe functions and mechanisms of long noncoding RNAs. Nature Structural & Molecular Biology. 22: 29-35. PMID 25565030 DOI: 10.1038/Nsmb.2921  0.673
2015 Buenrostro JD, Wu B, Chang HY, Greenleaf WJ. ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 109: 21.29.1-9. PMID 25559105 DOI: 10.1002/0471142727.Mb2129S109  0.317
2015 Quinn JJ, Chang HY. In situ dissection of RNA functional subunits by domain-specific chromatin isolation by RNA purification (dChIRP). Methods in Molecular Biology (Clifton, N.J.). 1262: 199-213. PMID 25555583 DOI: 10.1007/978-1-4939-2253-6_12  0.415
2015 Calo E, Flynn RA, Martin L, Spitale RC, Chang HY, Wysocka J. RNA helicase DDX21 coordinates transcription and ribosomal RNA processing. Nature. 518: 249-53. PMID 25470060 DOI: 10.1038/Nature13923  0.699
2015 Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Dissecting noncoding and pathogen RNA-protein interactomes. Rna (New York, N.Y.). 21: 135-43. PMID 25411354 DOI: 10.1261/Rna.047803.114  0.68
2014 Paik KJ, Qu K, Hsueh B, Torre EA, Flynn RA, Chung MT, Spencley A, Wang KC, Wu JC, Longaker MT, Chang HY, Wan DC. Abstract 158: Identification of BMP-Responsive Long Noncoding RNAs in Pluripotent Cells. Plastic and Reconstructive Surgery. 133: 174. PMID 25942268 DOI: 10.1097/01.Prs.0000444987.90678.B2  0.595
2014 Batista PJ, Molinie B, Wang J, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, ... ... Chang HY, et al. m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 15: 707-19. PMID 25456834 DOI: 10.1016/J.Stem.2014.09.019  0.717
2014 Benitez CM, Qu K, Sugiyama T, Pauerstein PT, Liu Y, Tsai J, Gu X, Ghodasara A, Arda HE, Zhang J, Dekker JD, Tucker HO, Chang HY, Kim SK. An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development. Plos Genetics. 10: e1004645. PMID 25330008 DOI: 10.1371/Journal.Pgen.1004645  0.399
2014 Quinn JJ, Chang HY. RNA switch at enhancers. Nature Genetics. 46: 929-31. PMID 25162802 DOI: 10.1038/Ng.3074  0.415
2014 Spitale RC, Flynn RA, Torre EA, Kool ET, Chang HY. RNA structural analysis by evolving SHAPE chemistry. Wiley Interdisciplinary Reviews. Rna. 5: 867-81. PMID 25132067 DOI: 10.1002/Wrna.1253  0.685
2014 Li L, Chang HY. Physiological roles of long noncoding RNAs: insight from knockout mice. Trends in Cell Biology. 24: 594-602. PMID 25022466 DOI: 10.1016/J.Tcb.2014.06.003  0.462
2014 Quinn JJ, Ilik IA, Qu K, Georgiev P, Chu C, Akhtar A, Chang HY. Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nature Biotechnology. 32: 933-40. PMID 24997788 DOI: 10.1038/Nbt.2943  0.434
2014 Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY. Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. Nature Structural & Molecular Biology. 21: 585-90. PMID 24929436 DOI: 10.1038/Nsmb.2842  0.766
2014 Flynn RA, Chang HY. Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell. 14: 752-61. PMID 24905165 DOI: 10.1016/J.Stem.2014.05.014  0.444
2014 Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, Greenleaf WJ. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nature Biotechnology. 32: 562-8. PMID 24727714 DOI: 10.1038/Nbt.2880  0.549
2014 Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife. 3: e02046. PMID 24521543 DOI: 10.7554/Elife.02046  0.533
2014 Wan Y, Qu K, Zhang QC, Flynn RA, Manor O, Ouyang Z, Zhang J, Spitale RC, Snyder MP, Segal E, Chang HY. Landscape and variation of RNA secondary structure across the human transcriptome. Nature. 505: 706-9. PMID 24476892 DOI: 10.1038/Nature12946  0.824
2014 Mazumdar C, Li R, Buenrostro J, Chang HY, Majeti R. Cohesin Complex Mutations Impair Differentiation of Human Hematopoietic Stem and Progenitor Cells Blood. 124: 4785-4785. DOI: 10.1182/Blood.V124.21.4785.4785  0.342
2014 Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of Native Chromatin for Fast and Sensitive Mulitmodal Analysis of Chromatin Architecture Biophysical Journal. 106: 77a. DOI: 10.1016/J.Bpj.2013.11.503  0.393
2013 Harcourt EM, Ehrenschwender T, Batista PJ, Chang HY, Kool ET. Identification of a selective polymerase enables detection of N(6)-methyladenosine in RNA. Journal of the American Chemical Society. 135: 19079-82. PMID 24328136 DOI: 10.1021/Ja4105792  0.705
2013 Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... ... Chang HY, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/J.Cell.2013.09.028  0.368
2013 Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nature Methods. 10: 1213-8. PMID 24097267 DOI: 10.1038/Nmeth.2688  0.345
2013 Li L, Liu B, Wapinski OL, Tsai MC, Qu K, Zhang J, Carlson JC, Lin M, Fang F, Gupta RA, Helms JA, Chang HY. Targeted disruption of Hotair leads to homeotic transformation and gene derepression. Cell Reports. 5: 3-12. PMID 24075995 DOI: 10.1016/J.Celrep.2013.09.003  0.419
2013 Schmitt AM, Chang HY. Gene regulation: Long RNAs wire up cancer growth. Nature. 500: 536-7. PMID 23945584 DOI: 10.1038/Nature12548  0.702
2013 Rapicavoli NA, Qu K, Zhang J, Mikhail M, Laberge RM, Chang HY. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. Elife. 2: e00762. PMID 23898399 DOI: 10.7554/Elife.00762  0.331
2013 Ilik IA, Quinn JJ, Georgiev P, Tavares-Cadete F, Maticzka D, Toscano S, Wan Y, Spitale RC, Luscombe N, Backofen R, Chang HY, Akhtar A. Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila. Molecular Cell. 51: 156-73. PMID 23870142 DOI: 10.1016/J.Molcel.2013.07.001  0.759
2013 Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Research. 73: 5449-58. PMID 23832664 DOI: 10.1158/0008-5472.Can-13-1178  0.325
2013 Wan Y, Qu K, Ouyang Z, Chang HY. Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing. Nature Protocols. 8: 849-69. PMID 23558785 DOI: 10.1038/Nprot.2013.045  0.654
2013 Batista PJ, Chang HY. Long noncoding RNAs: cellular address codes in development and disease. Cell. 152: 1298-307. PMID 23498938 DOI: 10.1016/J.Cell.2013.02.012  0.72
2013 Gomez JA, Wapinski OL, Yang YW, Bureau JF, Gopinath S, Monack DM, Chang HY, Brahic M, Kirkegaard K. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell. 152: 743-54. PMID 23415224 DOI: 10.1016/J.Cell.2013.01.015  0.671
2013 Batista PJ, Chang HY. Cytotopic localization by long noncoding RNAs. Current Opinion in Cell Biology. 25: 195-9. PMID 23279909 DOI: 10.1016/J.Ceb.2012.12.001  0.744
2013 Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, ... ... Chang HY, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493: 231-5. PMID 23201690 DOI: 10.1038/Nature11661  0.822
2013 Spitale RC, Crisalli P, Flynn RA, Torre EA, Kool ET, Chang HY. RNA SHAPE analysis in living cells. Nature Chemical Biology. 9: 18-20. PMID 23178934 DOI: 10.1038/Nchembio.1131  0.697
2013 Ouyang Z, Snyder MP, Chang HY. SeqFold: genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data. Genome Research. 23: 377-87. PMID 23064747 DOI: 10.1101/Gr.138545.112  0.539
2013 Chang AL, Bitter PH, Qu K, Lin M, Rapicavoli NA, Chang HY. Rejuvenation of gene expression pattern of aged human skin by broadband light treatment: a pilot study. The Journal of Investigative Dermatology. 133: 394-402. PMID 22931923 DOI: 10.1038/Jid.2012.287  0.336
2013 Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Author response: Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency Elife. DOI: 10.7554/Elife.02046.013  0.531
2013 Chang HY. Abstract SY31-03: Genome regulation by long noncoding RNAs. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy31-03  0.487
2013 Abignano G, Hermes H, Esteves F, Gillespie J, Chang HY, Jimenez SA, Emery P, Galdo FD. SAT0022 Palmoplantar specific long NCRNA hotair drives myofibroblasts specific signature in systemic sclerosis Annals of the Rheumatic Diseases. 71: 478-478. DOI: 10.1136/Annrheumdis-2012-Eular.2970  0.363
2013 Schmitt A, Hung T, Flynn R, Payumo A, Peres-da-Silva A, Kenzelmann Broz D, Attardi L, Chen J, Chang H. Regulation of the DNA Damage Response by an Inducible Long Noncoding RNA International Journal of Radiation Oncology*Biology*Physics. 87: S19. DOI: 10.1016/J.Ijrobp.2013.06.055  0.702
2012 Siprashvili Z, Webster DE, Kretz M, Johnston D, Rinn JL, Chang HY, Khavari PA. Identification of proteins binding coding and non-coding human RNAs using protein microarrays. Bmc Genomics. 13: 633. PMID 23157412 DOI: 10.1186/1471-2164-13-633  0.639
2012 Martin L, Meier M, Lyons SM, Sit RV, Marzluff WF, Quake SR, Chang HY. Systematic reconstruction of RNA functional motifs with high-throughput microfluidics Nature Methods. 9: 1192-1194. PMID 23142872 DOI: 10.1038/Nmeth.2225  0.427
2012 Chisholm KM, Wan Y, Li R, Montgomery KD, Chang HY, West RB. Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. Plos One. 7: e47998. PMID 23133536 DOI: 10.1371/Journal.Pone.0047998  0.643
2012 Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY. Genome-wide measurement of RNA folding energies. Molecular Cell. 48: 169-81. PMID 22981864 DOI: 10.1016/J.Molcel.2012.08.008  0.663
2012 Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, et al. Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood. 120: 3288-97. PMID 22936659 DOI: 10.1182/Blood-2012-04-423061  0.45
2012 Brunner AL, Beck AH, Edris B, Sweeney RT, Zhu SX, Li R, Montgomery K, Varma S, Gilks T, Guo X, Foley JW, Witten DM, Giacomini CP, Flynn RA, Pollack JR, ... ... Chang HY, et al. Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers. Genome Biology. 13: R75. PMID 22929540 DOI: 10.1186/Gb-2012-13-8-R75  0.432
2012 Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, ... ... Chang HY, et al. The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. Cancer Discovery. 2: 638-51. PMID 22728437 DOI: 10.1158/2159-8290.Cd-12-0093  0.642
2012 Rinn JL, Chang HY. Genome regulation by long noncoding RNAs. Annual Review of Biochemistry. 81: 145-66. PMID 22663078 DOI: 10.1182/Blood.V122.21.Sci-29.Sci-29  0.676
2012 Martin L, Chang HY. Uncovering the role of genomic "dark matter" in human disease. The Journal of Clinical Investigation. 122: 1589-95. PMID 22546862 DOI: 10.1172/Jci60020  0.408
2012 Chu C, Quinn J, Chang HY. Chromatin isolation by RNA purification (ChIRP). Journal of Visualized Experiments : Jove. PMID 22472705 DOI: 10.3791/3912  0.492
2012 Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes & Development. 26: 338-43. PMID 22302877 DOI: 10.1101/Gad.182121.111  0.811
2012 Wang P, McKnight KD, Wong DJ, Rodriguez RT, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang HY, Kim SK. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells and Development. 21: 2273-87. PMID 22236333 DOI: 10.1089/Scd.2011.0416  0.352
2012 Flynn RA, Chang HY. Active chromatin and noncoding RNAs: an intimate relationship. Current Opinion in Genetics & Development. 22: 172-8. PMID 22154525 DOI: 10.1016/J.Gde.2011.11.002  0.442
2012 Marques M, Nieves B, Chen R, Vaka D, Chan C, Zheng G, Chang H, Weissman I, Sweet-Cordero A. Abstract 1427: Signal rewiring induced by EWS/FLI-1 in mouse and human mesenchymal stem cells Cancer Research. 72: 1427-1427. DOI: 10.1158/1538-7445.Am2012-1427  0.756
2011 Chu C, Qu K, Zhong FL, Artandi SE, Chang HY. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Molecular Cell. 44: 667-78. PMID 21963238 DOI: 10.1016/J.Molcel.2011.08.027  0.469
2011 Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/J.Stem.2011.09.002  0.359
2011 Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Molecular Cell. 43: 904-14. PMID 21925379 DOI: 10.1016/J.Molcel.2011.08.018  0.575
2011 Wan Y, Kertesz M, Spitale RC, Segal E, Chang HY. Understanding the transcriptome through RNA structure. Nature Reviews. Genetics. 12: 641-55. PMID 21850044 DOI: 10.1038/Nrg3049  0.769
2011 Alastalo TP, Li M, De Jesus Perez V, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M. Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival Journal of Clinical Investigation. 121: 3735-3746. PMID 21821917 DOI: 10.1172/Jci43382  0.316
2011 Kawahara TLA, Rapicavoli NA, Wu AR, Qu K, Quake SR, Chang HY. Dynamic chromatin localization of sirt6 shapes stress- and aging-related transcriptional networks Plos Genetics. 7. PMID 21738489 DOI: 10.1371/Journal.Pgen.1002153  0.351
2011 Chen Y, Wan B, Wang KC, Cao F, Yang Y, Protacio A, Dou Y, Chang HY, Lei M. Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Reports. 12: 797-803. PMID 21660059 DOI: 10.1038/Embor.2011.101  0.507
2011 Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, ... ... Chang HY, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nature Genetics. 43: 621-9. PMID 21642992 DOI: 10.1038/Ng.848  0.485
2011 Wapinski O, Chang HY. Long noncoding RNAs and human disease. Trends in Cell Biology. 21: 354-61. PMID 21550244 DOI: 10.1016/J.Tcb.2011.04.001  0.429
2011 Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature. 472: 120-4. PMID 21423168 DOI: 10.1038/Nature09819  0.606
2011 Spitale RC, Tsai MC, Chang HY. RNA templating the epigenome: long noncoding RNAs as molecular scaffolds. Epigenetics : Official Journal of the Dna Methylation Society. 6: 539-43. PMID 21393997 DOI: 10.4161/Epi.6.5.15221  0.684
2011 Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Research. 71: 3-7. PMID 21199792 DOI: 10.1158/0008-5472.Can-10-2483  0.689
2011 Wapinski O, Chang HY. Corrigendum: Long noncoding RNAs and human disease. [Trends in Cell Biology 21 (2011), 354-361] Trends in Cell Biology. 21: 561. DOI: 10.1016/J.Tcb.2011.08.004  0.351
2010 Ouyang Z, Zheng GX, Chang HY. Noncoding RNA landmarks of pluripotency and reprogramming. Cell Stem Cell. 7: 649-50. PMID 21112559 DOI: 10.1016/J.Stem.2010.11.018  0.76
2010 Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/Jcb.201003048  0.634
2010 Hung T, Chang HY. Long noncoding RNA in genome regulation: prospects and mechanisms. Rna Biology. 7: 582-5. PMID 20930520 DOI: 10.4161/Rna.7.5.13216  0.501
2010 Wan Y, Chang HY. HOTAIR: Flight of noncoding RNAs in cancer metastasis. Cell Cycle (Georgetown, Tex.). 9: 3391-2. PMID 20864820 DOI: 10.4161/Cc.9.17.13122  0.674
2010 Kertesz M, Wan Y, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E. Genome-wide measurement of RNA secondary structure in yeast. Nature. 467: 103-7. PMID 20811459 DOI: 10.1038/Nature09322  0.741
2010 Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, Shi Y, Segal E, Chang HY. Long noncoding RNA as modular scaffold of histone modification complexes. Science (New York, N.Y.). 329: 689-93. PMID 20616235 DOI: 10.1126/Science.1192002  0.62
2010 Tsai MC, Wang JK, Chang HY. Tumor suppression by the histone demethylase UTX. Cell Cycle (Georgetown, Tex.). 9: 2043-4. PMID 20505331 DOI: 10.4161/Cc.9.11.11845  0.428
2010 Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, ... ... Chang HY, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 464: 1071-6. PMID 20393566 DOI: 10.1038/Nature08975  0.712
2010 Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY. The histone demethylase UTX enables RB-dependent cell fate control. Genes & Development. 24: 327-32. PMID 20123895 DOI: 10.1101/Gad.1882610  0.687
2010 Sargent JL, Milano A, Bhattacharyya S, Varga J, Connolly MK, Chang HY, Whitfield ML. A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity. The Journal of Investigative Dermatology. 130: 694-705. PMID 19812599 DOI: 10.1038/Jid.2009.318  0.307
2010 Kertesz M, Wan Y, Mazor E, Rinn J, Nutter R, Chang H, Segal E. Probing RNA structure genome-wide using high throughput sequencing Nature Protocols. DOI: 10.1038/Nprot.2010.152  0.723
2009 Chang HY. Anatomic demarcation of cells: genes to patterns. Science (New York, N.Y.). 326: 1206-7. PMID 19965461 DOI: 10.1126/Science.1175686  0.378
2009 Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 14016-21. PMID 19666525 DOI: 10.1073/Pnas.0906549106  0.512
2009 Mace KA, Restivo TE, Rinn JL, Paquet AC, Chang HY, Young DM, Boudreau NJ. HOXA3 modulates injury-induced mobilization and recruitment of bone marrow-derived cells. Stem Cells (Dayton, Ohio). 27: 1654-65. PMID 19544454 DOI: 10.1002/Stem.90  0.567
2009 Chang HY, Cuvier O, Dekker J. Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization. Embo Reports. 10: 689-93. PMID 19525922 DOI: 10.1038/Embor.2009.136  0.343
2009 Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 15: 477-88. PMID 19477427 DOI: 10.1016/J.Ccr.2009.04.002  0.331
2009 Wang KC, Helms JA, Chang HY. Regeneration, repair and remembering identity: the three Rs of Hox gene expression. Trends in Cell Biology. 19: 268-75. PMID 19428253 DOI: 10.1016/J.Tcb.2009.03.007  0.598
2009 Rando OJ, Chang HY. Genome-wide views of chromatin structure. Annual Review of Biochemistry. 78: 245-71. PMID 19317649 DOI: 10.1146/Annurev.Biochem.78.071107.134639  0.37
2009 Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, Chang HY, Shurtleff SA, Downing JR, Cleary ML. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell. 4: 129-40. PMID 19200802 DOI: 10.1016/J.Stem.2008.11.015  0.586
2009 Hung T, Binda O, Champagne KS, Kuo AJ, Johnson K, Chang HY, Simon MD, Kutateladze TG, Gozani O. ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Molecular Cell. 33: 248-56. PMID 19187765 DOI: 10.1016/J.Molcel.2008.12.016  0.303
2009 Chung L, Fiorentino DF, Benbarak MJ, Adler AS, Mariano MM, Paniagua RT, Milano A, Connolly MK, Ratiner BD, Wiskocil RL, Whitfield ML, Chang HY, Robinson WH. Molecular framework for response to imatinib mesylate in systemic sclerosis. Arthritis and Rheumatism. 60: 584-91. PMID 19180499 DOI: 10.1002/Art.24221  0.619
2009 Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, McCord RA, Ongaigui KC, Boxer LD, Chang HY, Chua KF. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 136: 62-74. PMID 19135889 DOI: 10.1016/J.Cell.2008.10.052  0.639
2008 Sääf AM, Tengvall-Linder M, Chang HY, Adler AS, Wahlgren CF, Scheynius A, Nordenskjöld M, Bradley M. Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. Plos One. 3: e4017. PMID 19107207 DOI: 10.1371/Journal.Pone.0004017  0.657
2008 Wong DJ, Segal E, Chang HY. Stemness, cancer and cancer stem cells. Cell Cycle (Georgetown, Tex.). 7: 3622-4. PMID 19029796 DOI: 10.4161/Cc.7.23.7104  0.346
2008 Nuyten DS, Hastie T, Chi JT, Chang HY, van de Vijver MJ. Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification. European Journal of Cancer (Oxford, England : 1990). 44: 2319-29. PMID 18715778 DOI: 10.1016/J.Ejca.2008.07.015  0.301
2008 Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science (New York, N.Y.). 321: 843-7. PMID 18687966 DOI: 10.1126/Science.1159407  0.317
2008 Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/Gad.1673508  0.332
2008 Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. The Journal of Clinical Investigation. 118: 1712-26. PMID 18414681 DOI: 10.1172/Jci34523  0.55
2008 Wong DJ, Liu H, Ridky TW, Cassarino D, Segal E, Chang HY. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell. 2: 333-44. PMID 18397753 DOI: 10.1016/J.Stem.2008.02.009  0.364
2008 Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492-6. PMID 18337721 DOI: 10.1038/Nature06736  0.318
2008 Rinn JL, Wang JK, Liu H, Montgomery K, van de Rijn M, Chang HY. A systems biology approach to anatomic diversity of skin. The Journal of Investigative Dermatology. 128: 776-82. PMID 18337710 DOI: 10.1038/Sj.Jid.5700986  0.605
2008 Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle (Georgetown, Tex.). 7: 556-9. PMID 18256548 DOI: 10.4161/Cc.7.5.5490  0.64
2008 Sinha S, Adler AS, Field Y, Chang HY, Segal E. Systematic functional characterization of cis-regulatory motifs in human core promoters. Genome Research. 18: 477-88. PMID 18256240 DOI: 10.1101/Gr.6828808  0.674
2008 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY. A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes & Development. 22: 303-7. PMID 18245445 DOI: 10.1101/gad.1610508  0.549
2008 Adler AS, Littlepage LE, Lin M, Kawahara TL, Wong DJ, Werb Z, Chang HY. CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. Cancer Research. 68: 506-15. PMID 18199546 DOI: 10.1158/0008-5472.Can-07-3060  0.629
2008 Wong DJ, Nuyten DS, Regev A, Lin M, Adler AS, Segal E, van de Vijver MJ, Chang HY. Revealing targeted therapy for human cancer by gene module maps. Cancer Research. 68: 369-78. PMID 18199530 DOI: 10.1158/0008-5472.Can-07-0382  0.666
2007 Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E, Chang HY. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes & Development. 21: 3244-57. PMID 18055696 DOI: 10.1101/Gad.1588507  0.642
2007 Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature. 449: 689-94. PMID 17851529 DOI: 10.1038/Nature06192  0.626
2007 Chang HY, Cotsarelis G. Turning skin into embryonic stem cells. Nature Medicine. 13: 783-4. PMID 17618266 DOI: 10.1038/Nm0707-783  0.322
2007 Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129: 1311-23. PMID 17604720 DOI: 10.1016/J.Cell.2007.05.022  0.661
2007 Liu H, Adler AS, Segal E, Chang HY. A transcriptional program mediating entry into cellular quiescence. Plos Genetics. 3: e91. PMID 17559306 DOI: 10.1371/Journal.Pgen.0030091  0.678
2007 O'Geen H, Squazzo SL, Iyengar S, Blahnik K, Rinn JL, Chang HY, Green R, Farnham PJ. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. Plos Genetics. 3: e89. PMID 17542650 DOI: 10.1371/Journal.Pgen.0030089  0.623
2007 Segal E, Sirlin CB, Ooi C, Adler AS, Gollub J, Chen X, Chan BK, Matcuk GR, Barry CT, Chang HY, Kuo MD. Decoding global gene expression programs in liver cancer by noninvasive imaging. Nature Biotechnology. 25: 675-80. PMID 17515910 DOI: 10.1038/Nbt1306  0.643
2006 Chang HY, Thomson JA, Chen X. Microarray analysis of stem cells and differentiation. Methods in Enzymology. 420: 225-54. PMID 17161699 DOI: 10.1016/S0076-6879(06)20010-7  0.393
2006 DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Caspi R, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. The Journal of Experimental Medicine. 203: 2727-35. PMID 17116738 DOI: 10.1084/Jem.20061864  0.541
2006 Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse HJ, Bartelink H, Brown PO, Chang HY, van de Vijver MJ. Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Research : Bcr. 8: R62. PMID 17069664 DOI: 10.1186/Bcr1614  0.744
2006 Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 103: 14842-7. PMID 17003113 DOI: 10.1073/Pnas.0606857103  0.777
2006 Rinn JL, Bondre C, Gladstone HB, Brown PO, Chang HY. Anatomic demarcation by positional variation in fibroblast gene expression programs. Plos Genetics. 2: e119. PMID 16895450 DOI: 10.1371/Journal.Pgen.0020119  0.677
2006 Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, Herzenberg LA, Felsher DW. MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Research. 66: 6598-605. PMID 16818632 DOI: 10.1158/0008-5472.Can-05-3115  0.632
2006 Adler AS, Chang HY. From description to causality: mechanisms of gene expression signatures in cancer. Cell Cycle (Georgetown, Tex.). 5: 1148-51. PMID 16721055 DOI: 10.4161/Cc.5.11.2798  0.67
2006 Adler AS, Lin M, Horlings H, Nuyten DS, van de Vijver MJ, Chang HY. Genetic regulators of large-scale transcriptional signatures in cancer. Nature Genetics. 38: 421-30. PMID 16518402 DOI: 10.1038/Ng1752  0.666
2006 DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Fong L, Anderson MS. CORRECTION Journal of Experimental Medicine. 204: 203-203. DOI: 10.1084/Jem.20061864121306C  0.478
2005 Wong DJ, Chang HY. Learning more from microarrays: insights from modules and networks. The Journal of Investigative Dermatology. 125: 175-82. PMID 16098025 DOI: 10.1111/J.0022-202X.2005.23827.X  0.352
2005 Tang J, Chang HY, Yang X. The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62. Febs Letters. 579: 2883-90. PMID 15878163 DOI: 10.1016/J.Febslet.2005.04.029  0.333
2005 Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proceedings of the National Academy of Sciences of the United States of America. 102: 3738-43. PMID 15701700 DOI: 10.1073/Pnas.0409462102  0.753
2005 Nuyten D, Chang H, Brown P, Vijver MVd. Reproducibility of molecular portraits in early stage breast cancer Breast Cancer Research. 7: 1-2. DOI: 10.1186/Bcr1156  0.435
2004 Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. Plos Biology. 2: E7. PMID 14737219 DOI: 10.1371/Journal.Pbio.0020007  0.79
2003 Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 100: 10623-8. PMID 12963823 DOI: 10.1073/Pnas.1434429100  0.504
2003 Chi JT, Chang HY, Wang NN, Chang DS, Dunphy N, Brown PO. Genomewide view of gene silencing by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 100: 6343-6. PMID 12730368 DOI: 10.1073/Pnas.1037853100  0.617
2002 Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO. Diversity, topographic differentiation, and positional memory in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 12877-82. PMID 12297622 DOI: 10.1073/Pnas.162488599  0.545
1999 Chang HY, Yang X, Baltimore D. Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 96: 1252-6. PMID 9990010 DOI: 10.1073/Pnas.96.4.1252  0.434
1998 Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science (New York, N.Y.). 281: 1860-3. PMID 9743501 DOI: 10.1126/Science.281.5384.1860  0.423
1998 Yang X, Chang HY, Baltimore D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science (New York, N.Y.). 281: 1355-7. PMID 9721101 DOI: 10.1126/Science.281.5381.1355  0.451
1998 Yang X, Chang HY, Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Molecular Cell. 1: 319-25. PMID 9659928 DOI: 10.1016/S1097-2765(00)80032-5  0.41
1997 Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 89: 1067-76. PMID 9215629 DOI: 10.1016/S0092-8674(00)80294-9  0.423
Low-probability matches (unlikely to be authored by this person)
2022 Abe BT, Wesselhoeft RA, Chen R, Anderson DG, Chang HY. Circular RNA migration in agarose gel electrophoresis. Molecular Cell. PMID 35358469 DOI: 10.1016/j.molcel.2022.03.008  0.3
2021 Yu B, Qi Y, Li R, Shi Q, Satpathy A, Chang HY. B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells. Biorxiv : the Preprint Server For Biology. PMID 33442682 DOI: 10.1101/2021.01.03.425167  0.298
2016 Mumbach MR, Rubin AJ, Flynn RA, Dai C, Khavari PA, Greenleaf WJ, Chang HY. HiChIP: efficient and sensitive analysis of protein-directed genome architecture. Nature Methods. PMID 27643841 DOI: 10.1038/Nmeth.3999  0.297
2024 Hauth A, Panten J, Kneuss E, Picard C, Servant N, Rall I, Pérez-Rico YA, Clerquin L, Servaas N, Villacorta L, Jung F, Luong C, Chang HY, Zaugg JB, Stegle O, et al. Escape from X inactivation is directly modulated by levels of Xist non-coding RNA. Biorxiv : the Preprint Server For Biology. PMID 38559194 DOI: 10.1101/2024.02.22.581559  0.296
2018 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, ... ... Chang HY, et al. Retraction Note: DDX5 and its associated lncRNA Rmrp modulate T17 cell effector functions. Nature. PMID 29973715 DOI: 10.1038/S41586-018-0311-Z  0.29
2017 Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, et al. Generation of pure GABAergic neurons by transcription factor programming. Nature Methods. PMID 28504679 DOI: 10.1038/Nmeth.4291  0.29
2021 Trevino AE, Müller F, Andersen J, Sundaram L, Kathiria A, Shcherbina A, Farh K, Chang HY, Pașca AM, Kundaje A, Pașca SP, Greenleaf WJ. Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution. Cell. PMID 34390642 DOI: 10.1016/j.cell.2021.07.039  0.289
2020 Wu K, Zou J, Chang HY. RNA-GPS Predicts SARS-CoV-2 RNA Localization to Host Mitochondria and Nucleolus. Biorxiv : the Preprint Server For Biology. PMID 32511373 DOI: 10.1101/2020.04.28.065201  0.289
2020 Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Jean GH, Stevens BA, Lee JY, Rustagi A, Rogers AJ, Powell AE, Hunter M, Najeeb J, Otrelo-Cardoso AR, Yost KE, ... ... Chang HY, et al. Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2. Cell Host & Microbe. PMID 32941787 DOI: 10.1016/J.Chom.2020.09.002  0.288
2012 Chow NH, Chang HY, Chen SH, Liu HS. 212 The Involvement of DNA Double-strand Break Repair in Receptor Tyrosine Kinase RON-mediated Cancer Cell Response to Hypoxia European Journal of Cancer. 48. DOI: 10.1016/S0959-8049(12)70907-3  0.285
2021 Granja JM, Corces MR, Pierce SE, Bagdatli ST, Choudhry H, Chang HY, Greenleaf WJ. ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis. Nature Genetics. PMID 33633365 DOI: 10.1038/s41588-021-00790-6  0.283
2017 Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY. Corrigendum: Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nature Genetics. 49: 970. PMID 28546577 DOI: 10.1038/Ng0617-970A  0.281
2014 Chang AL, Atzmon G, Bergman A, Brugmann S, Atwood SX, Chang HY, Barzilai N. Identification of genes promoting skin youthfulness by genome-wide association study. The Journal of Investigative Dermatology. 134: 651-7. PMID 24037343 DOI: 10.1038/Jid.2013.381  0.281
2020 Vardhana SA, Hwee MA, Berisa M, Wells DK, Yost KE, King B, Smith M, Herrera PS, Chang HY, Satpathy AT, van den Brink MRM, Cross JR, Thompson CB. Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen. Nature Immunology. PMID 32661364 DOI: 10.1038/S41590-020-0725-2  0.28
2021 Wu KE, Yost KE, Chang HY, Zou J. BABEL enables cross-modality translation between multiomic profiles at single-cell resolution. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33827925 DOI: 10.1073/pnas.2023070118  0.28
2009 Chan DA, Kawahara TL, Sutphin PD, Chang HY, Chi JT, Giaccia AJ. Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell. 15: 527-38. PMID 19477431 DOI: 10.1016/J.Ccr.2009.04.010  0.276
2016 Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L. Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron. PMID 27693255 DOI: 10.1016/J.Neuron.2016.09.019  0.276
2007 Chang HY. Patterning skin pigmentation via dickkopf. The Journal of Investigative Dermatology. 127: 994-5. PMID 17435783 DOI: 10.1038/Sj.Jid.5700636  0.275
2023 Zheng R, Dunlap M, Lyu J, Gonzalez-Figueroa C, Bobkov G, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Vuong A, Flynn RA, Chang HY, Xiao X, Cheng C. LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity. Biorxiv : the Preprint Server For Biology. PMID 36865202 DOI: 10.1101/2023.02.23.529804  0.275
2021 Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, et al. Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions. Cell. PMID 33743211 DOI: 10.1016/j.cell.2021.03.012  0.274
2022 Wheeler JR, Whitney ON, Vogler TO, Nguyen ED, Pawlikowski B, Lester E, Cutler A, Elston T, Dalla Betta N, Parker KR, Yost KE, Vogel H, Rando TA, Chang HY, Johnson AM, et al. RNA-binding proteins direct myogenic cell fate decisions. Elife. 11. PMID 35695839 DOI: 10.7554/eLife.75844  0.271
2023 Wu KE, Zou JY, Chang H. Machine learning modeling of RNA structures: methods, challenges and future perspectives. Briefings in Bioinformatics. PMID 37280185 DOI: 10.1093/bib/bbad210  0.27
2018 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Chang HY, et al. Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 29899441 DOI: 10.1038/S41586-018-0227-7  0.27
2001 Chang HY, Yang X. Proteases for cell suicide: functions and regulation of caspases. Microbiology and Molecular Biology Reviews : Mmbr. 64: 821-46. PMID 11104820 DOI: 10.1128/Mmbr.64.4.821-846.2000  0.267
2021 Ram-Mohan N, Thair SA, Litzenburger UM, Cogill S, Andini N, Yang X, Chang HY, Yang S. Profiling chromatin accessibility responses in human neutrophils with sensitive pathogen detection. Life Science Alliance. 4. PMID 34145026 DOI: 10.26508/lsa.202000976  0.264
2021 Corley M, Flynn RA, Blue SM, Yee BA, Chang HY, Yeo GW. fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins. Star Protocols. 2: 100762. PMID 34485935 DOI: 10.1016/j.xpro.2021.100762  0.26
2018 Yost KE, Carter AC, Xu J, Litzenburger U, Chang HY. ATAC Primer Tool for targeted analysis of accessible chromatin. Nature Methods. 15: 304-305. PMID 29702633 DOI: 10.1038/Nmeth.4663  0.258
2023 Amaya L, Grigoryan L, Li Z, Lee A, Wender PA, Pulendran B, Chang HY. Circular RNA vaccine induces potent T cell responses. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302191120. PMID 37155869 DOI: 10.1073/pnas.2302191120  0.257
2022 Foster DS, Januszyk M, Delitto D, Yost KE, Griffin M, Guo J, Guardino N, Delitto AE, Chinta M, Burcham AR, Nguyen AT, Bauer-Rowe KE, Titan AL, Salhotra A, Jones RE, ... ... Chang HY, et al. Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin. Cancer Cell. PMID 36270275 DOI: 10.1016/j.ccell.2022.09.015  0.256
2020 Flynn RA, Belk JA, Qi Y, Yasumoto Y, Schmitz CO, Mumbach MR, Limaye A, Wei J, Alfajaro MM, Parker KR, Chang HY, Horvath TL, Carette JE, Bertozzi C, Wilen CB, et al. Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection. Biorxiv : the Preprint Server For Biology. PMID 33052334 DOI: 10.1101/2020.10.06.327445  0.256
2022 Ma Q, Yang L, Tolentino K, Wang G, Zhao Y, Litzenburger UM, Shi Q, Zhu L, Yang C, Jiao H, Zhang F, Li R, Tsai MC, Chen JA, Lai I, ... ... Chang HY, et al. Inducible lncRNA transgenic mice reveal continual role of in promoting breast cancer metastasis. Elife. 11. PMID 36579891 DOI: 10.7554/eLife.79126  0.255
2024 Cepika AM, Amaya L, Waichler C, Narula M, Mantilla MM, Thomas BC, Chen PP, Freeborn RA, Pavel-Dinu M, Nideffer J, Porteus M, Bacchetta R, Müller F, Greenleaf WJ, Chang HY, et al. Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells. Biorxiv : the Preprint Server For Biology. PMID 38559096 DOI: 10.1101/2024.03.07.582969  0.255
2024 Yan X, Mischel P, Chang H. Extrachromosomal DNA in cancer. Nature Reviews. Cancer. PMID 38409389 DOI: 10.1038/s41568-024-00669-8  0.252
2016 Li L, Helms JA, Chang HY. Comment on "Hotair Is Dispensable for Mouse Development". Plos Genetics. 12: e1006406. PMID 27977686 DOI: 10.1371/Journal.Pgen.1006406  0.252
2016 Mumbach M, Rubin A, Flynn R, Dai C, Khavari P, Greenleaf W, Chang H. HiChIP: Protein-centric chromatin conformation Protocol Exchange. DOI: 10.1038/Protex.2016.071  0.249
2012 Wu AR, Kawahara TLA, Rapicavoli NA, Riggelen JV, Shroff EH, Xu L, Felsher DW, Chang HY, Quake SR. High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation Lab On a Chip - Miniaturisation For Chemistry and Biology. 12: 2190-2198. PMID 22566096 DOI: 10.1039/C2Lc21290K  0.248
2014 Chang HY, Yuan LY, Hu TL, Chien CI, Lin YC, Tseng SF, Chang TW, Wang WK. Complete mitochondrial DNA genome of Parazacco spilurus (Cypriniformes: Cyprinidae). Mitochondrial Dna. PMID 24521497 DOI: 10.3109/19401736.2013.878926  0.248
2019 Hu MS, Leavitt T, Borrelli MR, Wan DC, Lorenz HP, Chang HY, Longaker MT. Embryonic Lineage Tracing Identifies Fibrogenic Potential in Ventral and Dorsal Mouse Dermis Plastic and Reconstructive Surgery. Global Open. 7: 1. DOI: 10.1097/01.Gox.0000579780.26078.Fc  0.247
2018 Tong J, Cao G, Zhang T, Sefik E, Amezcua Vesely MC, Broughton JP, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB. m6A mRNA methylation sustains Treg suppressive functions. Cell Research. PMID 29303144 DOI: 10.1038/Cr.2018.7  0.246
2014 Yuan LY, Wang WK, Lee CH, Chiu KH, Li YM, Kuo PC, Chang HY. Complete mitochondrial DNA genome of Metzia mesembrinum (Cypriniformes: Cyprinidae). Mitochondrial Dna. PMID 24521504 DOI: 10.3109/19401736.2014.880894  0.245
2016 Qu K, Garamszegi S, Wu F, Thorvaldsdottir H, Liefeld T, Ocana M, Borges-Rivera D, Pochet N, Robinson JT, Demchak B, Hull T, Ben-Artzi G, Blankenberg D, Barber GP, Lee BT, ... ... Chang HY, et al. Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. Nature Methods. PMID 26780094 DOI: 10.1038/Nmeth.3732  0.245
2018 Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, ... ... Chang HY, et al. Author response: The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders Elife. DOI: 10.7554/Elife.41770.043  0.244
2020 McGuire AL, Gabriel S, Tishkoff SA, Wonkam A, Chakravarti A, Furlong EEM, Treutlein B, Meissner A, Chang HY, López-Bigas N, Segal E, Kim JS. The road ahead in genetics and genomics. Nature Reviews. Genetics. PMID 32839576 DOI: 10.1038/S41576-020-0272-6  0.243
2018 Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Author response: Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons Elife. DOI: 10.7554/Elife.40197.020  0.241
2012 Rando TA, Chang HY. Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell. 148: 46-57. PMID 22265401 DOI: 10.1016/J.Cell.2012.01.003  0.24
1992 Zydowsky LD, Etzkorn FA, Chang HY, Ferguson SB, Stolz LA, Ho SI, Walsh CT. Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition. Protein Science : a Publication of the Protein Society. 1: 1092-9. PMID 1338979 DOI: 10.1002/Pro.5560010903  0.239
2009 Wong DJ, Chang HY. Skin tissue engineering Stembook. PMID 20614591 DOI: 10.3824/Stembook.1.44.1  0.239
2017 Syed A, Chang H, Schwartzberg B, Bremmer A, Boylan S, Lopez-Penalver C, Vito C, Davis M, Dooley W, Chakravarthy A, Croomer C, Proulx G, Golder S, Ivanov O, Fernandez K, et al. Abstract P1-10-19: Two-year follow-up results of a multi-center trial of intra-operative electronic brachytherapy during breast conservation surgery for early stage breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-10-19  0.238
2021 Wu S, Bafna V, Chang HY, Mischel PS. Extrachromosomal DNA: An Emerging Hallmark in Human Cancer. Annual Review of Pathology. PMID 34752712 DOI: 10.1146/annurev-pathmechdis-051821-114223  0.238
2016 Shaik M, Noel M, Schwartz K, Olson K, Chang H. Mpth-16. Expression Of Metabolic Enzymes As Predictors Of Prognosis In Patients With Aggressive Primary Brain Cancers Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.454  0.238
2010 Sadik H, Shah N, Gupta R, Chang H, Sukumar S. Abstract P4-01-03: The Homeobox Protein H0XC10 Is Overexpressed in Breast Cancer and Confers Resistance to Chemotherapy Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P4-01-03  0.237
2013 Whyte JL, Smith AA, Liu B, Manzano WR, Evans ND, Dhamdhere GR, Fang MY, Chang HY, Oro AE, Helms JA. Augmenting endogenous Wnt signaling improves skin wound healing. Plos One. 8: e76883. PMID 24204695 DOI: 10.1371/Journal.Pone.0076883  0.237
2018 Pattison J, Melo S, Piekos S, Torkelson J, Mumbach M, Rubin A, Li L, Zhen H, Chang H, Khavari P, Oro A. 1435 Dynamic morphogen-p63 chromatin interactions that guide epigenetic changes and p63 activity in surface ectoderm commitment Journal of Investigative Dermatology. 138: S243. DOI: 10.1016/J.Jid.2018.03.1453  0.234
2021 Marion-Poll L, Forêt B, Zielinski D, Massip F, Attia M, Carter AC, Syx L, Chang HY, Gendrel AV, Heard E. Locus specific epigenetic modalities of random allelic expression imbalance. Nature Communications. 12: 5330. PMID 34504093 DOI: 10.1038/s41467-021-25630-3  0.234
2019 desJardins-Park HE, Moore AL, Litzenburger U, Mascharak S, Chinta M, Ransom RC, Hu MS, Lorenz HP, Chang HY, Longaker MT. Intrinsic Chromatin State and Extrinsic Wound-Related Cues Can Coordinate to Activate Fibroblasts for Scarring Journal of the American College of Surgeons. 229. DOI: 10.1016/J.Jamcollsurg.2019.08.491  0.231
2021 Pierce SE, Granja JM, Corces MR, Brady JJ, Tsai MK, Pierce AB, Tang R, Chu P, Feldser DM, Chang HY, Bassik MC, Greenleaf WJ, Winslow MM. LKB1 inactivation modulates chromatin accessibility to drive metastatic progression. Nature Cell Biology. PMID 34341533 DOI: 10.1038/s41556-021-00728-4  0.228
2015 Gilchrest BA, Campisi J, Chang HY, Fisher GJ, Kulesz-Martin MF. Montagna Symposium 2014-skin aging: molecular mechanisms and tissue consequences. The Journal of Investigative Dermatology. 135: 950-3. PMID 25785950 DOI: 10.1038/Jid.2014.546  0.228
2021 Gennert DG, Lynn RC, Granja JM, Weber EW, Mumbach MR, Zhao Y, Duren Z, Sotillo E, Greenleaf WJ, Wong WH, Satpathy AT, Mackall CL, Chang HY. Dynamic chromatin regulatory landscape of human CAR T cell exhaustion. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34285077 DOI: 10.1073/pnas.2104758118  0.227
2013 Rapicavoli NA, Qu K, Zhang J, Mikhail M, Laberge R, Chang HY. Author response: A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics Elife. DOI: 10.7554/Elife.00762.013  0.226
2023 Lin MS, Jo SY, Luebeck J, Chang HY, Wu S, Mischel PS, Bafna V. Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors. Biorxiv : the Preprint Server For Biology. PMID 37162993 DOI: 10.1101/2023.04.24.537925  0.223
2020 Borrelli MR, Garcia J, Griffin M, Diaz NMD, Moore AL, Mascharak S, Duoto B, desJardins-Park H, Adem S, Lerbs T, Gastou M, Cui L, Januszyk M, Lorenz HP, Wan DC, ... ... Chang H, et al. Abstract 186: CD36 Antagonism Minimizes Skin Scarring By Inhibiting JUN-dependent Fibrotic Pathways Within Fibrogenic Fibroblast Subpopulations Plastic and Reconstructive Surgery. Global Open. 8: 126-127. DOI: 10.1097/01.Gox.0000667800.90500.3C  0.222
2018 Jeng M, Mumbach M, Granja J, Satpathy A, Chang H, Chang A. 823 Enhancer connectome functionally interrogates GWAS-identified intergenic SNPs associated with inflammatory skin conditions Journal of Investigative Dermatology. 138: S140. DOI: 10.1016/J.Jid.2018.03.833  0.222
2024 Pettie KP, Mumbach M, Lea AJ, Ayroles J, Chang HY, Kasowski M, Fraser HB. Chromatin activity identifies differential gene regulation across human ancestries. Genome Biology. 25: 21. PMID 38225662 DOI: 10.1186/s13059-024-03165-2  0.216
2020 Chinta M, Foster D, Nguyen A, Salhotra A, Gulati G, Ransom RC, Jones RE, Titan AL, Marshall CD, Mascharak S, Hu M, Januszyk M, Gurtner GC, Wan DC, Norton JA, ... Chang HY, et al. Abstract 190: Dermal Wounding Reveals Focal Adhesion Kinase Dependent Tissue-Resident Fibroblast Progenitors Plastic and Reconstructive Surgery. Global Open. 8: 129-130. DOI: 10.1097/01.Gox.0000667816.27720.Fd  0.213
2023 Dehkordi SR, Wong IT, Ni J, Luebeck J, Zhu K, Prasad G, Krockenberger L, Xu G, Chowdhury B, Rajkumar U, Caplin A, Muliaditan D, Coruh C, Jin Q, Turner K, ... ... Chang HY, et al. Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change. Biorxiv : the Preprint Server For Biology. PMID 38168210 DOI: 10.1101/2023.12.12.571349  0.212
2017 Syed A, Chang H, Schwartzberg B, Bremner A, Boylan S, Lopez-Penalver C, Vito C, Davis M, Dooley W, Chakravarthy A, Coomer C, Proulx G, Golder S, Ivanov O, Fernandez K, et al. Abstract P1-10-20: A multi-center trial of intra-operative electronic brachytherapy during breast conservation surgery for early stage breast cancer: Early results of unplanned boost participants Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-10-20  0.212
1995 Chang HY, Takei K, Sydor AM, Born T, Rusnak F, Jay DG. Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin Nature. 376: 686-690. PMID 7544441 DOI: 10.1038/376686A0  0.21
1997 Chang H, Gilbert W. A novel zebrafish gene expressed specifically in the photoreceptor cells of the retina Biochemical and Biophysical Research Communications. 237: 84-89. PMID 9266834 DOI: 10.1006/Bbrc.1997.7081  0.21
2003 Chang HY, Ridky TW, Kimball AB, Hughes E, Oro AE. Eruptive xanthomas associated with olanzapine use. Archives of Dermatology. 139: 1045-8. PMID 12925394 DOI: 10.1001/Archderm.139.8.1045  0.209
2004 Chang HY, Cooper ZA, Swetter SM, Marinkovich MP. Kinetics and specificity of fas ligand induction in toxic epidermal necrolysis. Archives of Dermatology. 140: 242-4. PMID 14967808 DOI: 10.1001/Archderm.140.2.242  0.208
2020 Borrelli MR, Leavitt T, Hu MS, Garcia JT, Januszyk M, Moore AL, Mascharak S, Griffin M, Wan DC, Lorenz HP, Gurtner GC, Chang HY, Longaker MT. Abstract 188: Prrx1 Marks Ventral Fibroblasts With Increased Fibrogenic Potential Plastic and Reconstructive Surgery. Global Open. 8: 127-128. DOI: 10.1097/01.Gox.0000667808.04197.30  0.207
2019 Stadtmauer EA, Cohen AD, Weber K, Lacey SF, Gonzalez VE, Melenhorst JJ, Fraietta JA, Plesa G, Shea J, Matlawski T, Cervini A, Mangan P, Gaymon A, Desjardins S, Lancaster E, ... ... Chang HY, et al. First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma. Blood. 134: 49. PMID 31724015 DOI: 10.1182/Blood-2019-122374  0.205
2020 Leylek R, Alcántara-Hernández M, Granja JM, Chavez M, Perez K, Diaz OR, Li R, Satpathy AT, Chang HY, Idoyaga J. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Reports. 32: 108180. PMID 32966789 DOI: 10.1016/j.celrep.2020.108180  0.204
2022 Daniel B, Yost KE, Hsiung S, Sandor K, Xia Y, Qi Y, Hiam-Galvez KJ, Black M, J Raposo C, Shi Q, Meier SL, Belk JA, Giles JR, Wherry EJ, Chang HY, et al. Divergent clonal differentiation trajectories of T cell exhaustion. Nature Immunology. PMID 36289450 DOI: 10.1038/s41590-022-01337-5  0.204
2021 Maas-Bauer K, Lohmeyer JK, Hirai T, Lopes Ramos T, Fazal FM, Litzenburger UM, Yost KE, Ribado JV, Kambham N, Wenokur A, Lin PY, Alvarez M, Mavers M, Baker J, Bhatt AS, ... Chang H, et al. Invariant Natural Killer T Cell Subsets Have Diverse Graft-Versus-Host-Disease-Preventing and Anti-Tumor Effects. Blood. PMID 34036317 DOI: 10.1182/blood.2021010887  0.203
1993 Molina MJ, Zhang R, Wooldridge PJ, McMahon JR, Kim JE, Chang HY, Beyer KD. Physical Chemistry of the H2SO4/HNO3/H2O System: Implications for Polar Stratospheric Clouds. Science (New York, N.Y.). 261: 1418-23. PMID 17745351 DOI: 10.1126/Science.261.5127.1418  0.199
2002 Sepe PS, Lahousse SA, Gemelli B, Chang H, Maeda T, Wands JR, de la Monte SM. Role of the aspartyl-asparaginyl-beta-hydroxylase gene in neuroblastoma cell motility. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 881-91. PMID 12118090 DOI: 10.1097/01.Lab.0000020406.91689.7F  0.198
2003 Chang HY, Wong KM, Bosenberg M, McKee PH, Haynes HA. Myelogenous leukemia cutis resembling stasis dermatitis. Journal of the American Academy of Dermatology. 49: 128-9. PMID 12833025 DOI: 10.1067/Mjd.2003.233  0.196
2024 Daniel B, Chen AY, Sandor K, Zhang W, Miao Z, Lareau CA, Yost KE, Chang HY, Satpathy AT. Regulation of immune signal integration and memory by inflammation-induced chromosome conformation. Biorxiv : the Preprint Server For Biology. PMID 38496446 DOI: 10.1101/2024.02.29.582872  0.195
2017 Chang HY, Nadeau KC. IL-4Rα Inhibitor for Atopic Disease. Cell. 170: 222. PMID 28708993 DOI: 10.1016/J.Cell.2017.06.046  0.19
2017 Schwartz K, Noel M, Nikolai M, Olson K, Zakem M, Elnabtity M, Clark J, Figueroa B, Chang H. Actr-80. Combining A Ketogenic Diet With Initial Chemotherapy & Radiation Therapies For Aggressive Gliomas, A Pilot Study Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.067  0.189
2012 Noch E, Pina-Oviedo S, Perez-Liz G, Bookland M, Del Valle L, Gordon J, Khalili K, Juratli TA, Peitzsch M, Geiger K, Schackert G, Eisenhofer G, Krex D, Chaumeil MM, Woods SM, ... ... Chang H, et al. LAB-METABOLIC PATHWAYS Neuro-Oncology. 14: vi53-vi55. DOI: 10.1093/Neuonc/Nos226  0.188
2016 Chang HY, Chang TC, Huang WY, Lee CT, Yen CJ, Tsai YS, Tzai TS, Chen SH, Chow NH. RON nuclear translocation under hypoxia potentiated chemoresistance to DNA double-strand break-inducing anti-cancer drugs. Molecular Cancer Therapeutics. PMID 26772202 DOI: 10.1158/1535-7163.MCT-15-0311  0.187
2005 Boyce KJ, Chang H, D'Souza CA, Kronstad JW. An Ustilago maydis septin is required for filamentous growth in culture and for full symptom development on maize Eukaryotic Cell. 4: 2044-2056. PMID 16339722 DOI: 10.1128/EC.4.12.2044-2056.2005  0.185
2015 Che YJ, Wu HW, Hung LY, Liu CA, Chang HY, Wang K, Lee GB. An integrated microfluidic system for screening of phage-displayed peptides specific to colon cancer cells and colon cancer stem cells. Biomicrofluidics. 9: 054121. PMID 26543513 DOI: 10.1063/1.4933067  0.184
1994 Beyer KD, Seago SW, Chang HY, Molina MJ. Composition and freezing of aqueous H2SO4/HNO3solutions under polar stratospheric conditions Geophysical Research Letters. 21: 871-874. DOI: 10.1029/94Gl00915  0.18
2015 Hung LY, Wang CH, Che YJ, Fu CY, Chang HY, Wang K, Lee GB. Screening of aptamers specific to colorectal cancer cells and stem cells by utilizing On-chip Cell-SELEX. Scientific Reports. 5: 10326. PMID 25999049 DOI: 10.1038/srep10326  0.18
2013 Chang ALS, Bitter PH, Qu K, Lin M, Rapicavoli NA, Chang HY. Correction to: Journal of Investigative Dermatology (2013) 133, 394–402; doi:10.1038/jid.2012.287; published online 30 August 2012 Journal of Investigative Dermatology. 133: 1691. DOI: 10.1038/Jid.2012.382  0.179
2020 Leavitt T, Hu MS, Borrelli MR, Januszyk M, Garcia JT, Ransom RC, Mascharak S, desJardins-Park HE, Litzenburger UM, Walmsley GG, Marshall CD, Moore AL, Duoto B, Adem S, Foster DS, ... ... Chang HY, et al. Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis. Cell Reports. 33: 108356. PMID 33176144 DOI: 10.1016/j.celrep.2020.108356  0.178
2021 Weber EW, Parker KR, Sotillo E, Lynn RC, Anbunathan H, Lattin J, Good Z, Belk JA, Daniel B, Klysz D, Malipatlolla M, Xu P, Bashti M, Heitzeneder S, Labanieh L, ... ... Chang HY, et al. Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling. Science (New York, N.Y.). 372. PMID 33795428 DOI: 10.1126/science.aba1786  0.178
2022 Yu B, Shi Q, Belk JA, Yost KE, Parker KR, Li R, Liu BB, Huang H, Lingwood D, Greenleaf WJ, Davis MM, Satpathy AT, Chang HY. Engineered cell entry links receptor biology with single-cell genomics. Cell. PMID 36516854 DOI: 10.1016/j.cell.2022.11.016  0.177
2019 Chang HY. Decision letter: Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist Elife. DOI: 10.7554/Elife.50256.Sa1  0.176
2022 Freitas KA, Belk JA, Sotillo E, Quinn PJ, Ramello MC, Malipatlolla M, Daniel B, Sandor K, Klysz D, Bjelajac J, Xu P, Burdsall KA, Tieu V, Duong VT, Donovan MG, ... ... Chang HY, et al. Enhanced T cell effector activity by targeting the Mediator kinase module. Science (New York, N.Y.). 378: eabn5647. PMID 36356142 DOI: 10.1126/science.abn5647  0.172
2020 Kebschull JM, Richman EB, Ringach N, Friedmann D, Albarran E, Kolluru SS, Jones RC, Allen WE, Wang Y, Cho SW, Zhou H, Ding JB, Chang HY, Deisseroth K, Quake SR, et al. Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set. Science (New York, N.Y.). 370. PMID 33335034 DOI: 10.1126/science.abd5059  0.169
2013 Ambady P, Holdhoff M, Ferrigno C, Grossman S, Anderson MD, Liu D, Conrad C, Penas-Prado M, Gilbert MR, Yung AWK, Groot Jd, Aoki T, Nishikawa R, Sugiyama K, Nonoguchi N, ... ... Chang H, et al. Neuro/Medical Oncology Neuro-Oncology. 15: 120-120. DOI: 10.1093/Neuonc/Not182  0.167
1996 Beyer KD, Seago SW, Chang HY, Molina MJ. Correction to “Composition and freezing of aqueous H2SO4/HNO3solutions under polar stratospheric conditions” Geophysical Research Letters. 23: 2715-2715. DOI: 10.1029/95Gl00085  0.167
2019 Chinta M, Mascharak S, Borrelli MR, Moore AL, Brewer RE, Sokol J, Kania G, Garibay E, Foster D, desJardins-Park H, Duoto B, Distler O, Gurtner GC, Lorenz HP, Wan DC, ... Chang HY, et al. Abstract 37 Plastic and Reconstructive Surgery - Global Open. 7: 27-28. DOI: 10.1097/01.Gox.0000558311.64337.Ba  0.167
2019 desJardins-Park HE, Moore AL, Litzenburger U, Marshall CD, Barnes LA, Mascharak S, Duoto B, Ransom RC, Foster DS, Hu MS, Lorenz HP, Chang HY, Longaker MT. Abstract 2 Plastic and Reconstructive Surgery - Global Open. 7: 1-2. DOI: 10.1097/01.Gox.0000558276.84941.68  0.167
2018 Hu MS, Leavitt T, Garcia JT, Ransom RC, Litzenburger UM, Walmsley GG, Marshall CD, Moore AL, Mascharak S, Chan CK, Wan DC, Lorenz P, Chang HY, Longaker MT. Abstract 43 Plastic and Reconstructive Surgery - Global Open. 6: 34. DOI: 10.1097/01.Gox.0000533908.18022.0D  0.167
2018 Ransom RC, Salhotra A, Carter AC, Jones RE, Foster DS, Chang HY, Wan DC, Longaker MT. Abstract 07 Plastic and Reconstructive Surgery - Global Open. 6: 5-6. DOI: 10.1097/01.Gox.0000533872.83475.9F  0.167
2016 Hu MS, Walmsley GG, Litzenburger U, Leavitt T, Maan ZN, Sinha R, Duscher D, Marshall CD, Weissman IL, Gurtner GC, Chang HY, Lorenz HP, Longaker MT. Abstract Plastic and Reconstructive Surgery - Global Open. 4: 128-129. DOI: 10.1097/01.Gox.0000503051.12364.Fa  0.167
2016 Leavitt T, Hu MS, Walmsley GG, Litzenburger UM, Ransom RC, Zielins ER, Chang HY, Lorenz HP, Longaker MT. Abstract Plastic and Reconstructive Surgery - Global Open. 4: 51. DOI: 10.1097/01.Gox.0000502931.14349.Cd  0.167
2022 Daniel B, Belk JA, Meier SL, Chen AY, Sandor K, Czimmerer Z, Varga Z, Bene K, Buquicchio FA, Qi Y, Kitano H, Wheeler JR, Foster DS, Januszyk M, Longaker MT, ... Chang HY, et al. Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state. Molecular Cell. PMID 36521490 DOI: 10.1016/j.molcel.2022.11.017  0.167
2014 Chang HY, Huang TC, Chen NN, Huang HC, Juan HF. Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Cell Death & Disease. 5: e1540. PMID 25429617 DOI: 10.1038/cddis.2014.504  0.166
2024 Dou DR, Zhao Y, Belk JA, Zhao Y, Casey KM, Chen DC, Li R, Yu B, Srinivasan S, Abe BT, Kraft K, Hellström C, Sjöberg R, Chang S, Feng A, ... ... Chang HY, et al. Xist ribonucleoproteins promote female sex-biased autoimmunity. Cell. 187: 733-749.e16. PMID 38306984 DOI: 10.1016/j.cell.2023.12.037  0.166
2023 Luebeck J, Ng AWT, Galipeau PC, Li X, Sanchez CA, Katz-Summercorn AC, Kim H, Jammula S, He Y, Lippman SM, Verhaak RGW, Maley CC, Alexandrov LB, Reid BJ, Fitzgerald RC, ... ... Chang HY, et al. Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus. Nature. PMID 37046089 DOI: 10.1038/s41586-023-05937-5  0.163
2020 Liu Q, Zaba L, Satpathy AT, Longmire M, Zhang W, Li K, Granja J, Guo C, Lin J, Li R, Tolentino K, Kania G, Distler O, Fiorentino D, Chung L, ... ... Chang HY, et al. Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis. Nature Communications. 11: 5843. PMID 33203843 DOI: 10.1038/s41467-020-19702-z  0.157
2015 Salahshourifar I, Vincent-Chong VK, Chang HY, Ser HL, Ramanathan A, Kallarakkal TG, Rahman ZA, Ismail SM, Prepageran N, Mustafa WM, Abraham MT, Tay KK, Zain RB. Downregulation of CRNN gene and genomic instability at 1q21.3 in oral squamous cell carcinoma. Clinical Oral Investigations. PMID 25846277 DOI: 10.1007/s00784-015-1467-7  0.156
2020 Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Stevens B, Lee JY, Rustagi A, Rogers AJ, Powell AE, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Chang HY, et al. Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32676593 DOI: 10.1101/2020.07.08.194456  0.154
2022 Tang Z, Lu Z, Chen B, Zhang W, Chang HY, Hu Z, Xu J. A genetic bottleneck of mitochondrial DNA during human lymphocyte development. Molecular Biology and Evolution. PMID 35482398 DOI: 10.1093/molbev/msac090  0.151
1991 Wang TC, Chang HY. Effect of rec mutations on viability and processing of DNA damaged by methylmethane sulfonate in xth nth nfo cells of Escherichia coli. Biochemical and Biophysical Research Communications. 180: 774-81. PMID 1953750 DOI: 10.1016/S0006-291X(05)81132-5  0.151
2021 Oh DY, Fong L, Newell EW, Turk MJ, Chi H, Chang HY, Satpathy AT, Fairfax B, Silva-Santos B, Lantz O. Toward a better understanding of T cells in cancer. Cancer Cell. 39: 1549-1552. PMID 34906313 DOI: 10.1016/j.ccell.2021.11.010  0.149
2013 Chang HY, Thomson JA, Chen X. Microarray Analysis of Stem Cells and Differentiation Handbook of Stem Cells. 1: 399-407. DOI: 10.1016/B978-0-12-385942-6.00034-2  0.148
2023 Tsuchida CA, Brandes N, Bueno R, Trinidad M, Mazumder T, Yu B, Hwang B, Chang C, Liu J, Sun Y, Hopkins CR, Parker KR, Qi Y, Hofman L, Satpathy AT, ... ... Chang HY, et al. Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells. Cell. 186: 4567-4582.e20. PMID 37794590 DOI: 10.1016/j.cell.2023.08.041  0.147
2021 Heitzeneder S, Bosse KR, Zhu Z, Zhelev D, Majzner RG, Radosevich MT, Dhingra S, Sotillo E, Buongervino S, Pascual-Pasto G, Garrigan E, Xu P, Huang J, Salzer B, Delaidelli A, ... ... Chang HY, et al. GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity. Cancer Cell. PMID 34971569 DOI: 10.1016/j.ccell.2021.12.005  0.146
2023 Tsuchida CA, Brandes N, Bueno R, Trinidad M, Mazumder T, Yu B, Hwang B, Chang C, Liu J, Sun Y, Hopkins CR, Parker KR, Qi Y, Satpathy AT, Stadtmauer EA, ... ... Chang HY, et al. Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells. Biorxiv : the Preprint Server For Biology. PMID 36993359 DOI: 10.1101/2023.03.22.533709  0.145
2021 Foster DS, Januszyk M, Yost KE, Chinta MS, Gulati GS, Nguyen AT, Burcham AR, Salhotra A, Ransom RC, Henn D, Chen K, Mascharak S, Tolentino K, Titan AL, Jones RE, ... ... Chang HY, et al. Integrated spatial multiomics reveals fibroblast fate during tissue repair. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34620713 DOI: 10.1073/pnas.2110025118  0.141
2020 Liu Q, Zaba LC, Satpathy AT, Longmire M, Zhang W, Li K, Granja J, Guo C, Lin J, Li R, Tolentino K, Kania G, Distler O, Fiorentino D, Chung L, ... ... Chang HY, et al. Author Correction: Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis. Nature Communications. 11: 6416. PMID 33318485 DOI: 10.1038/s41467-020-20411-w  0.141
2021 Yost KE, Chang HY, Satpathy AT. Recruiting T cells in cancer immunotherapy. Science (New York, N.Y.). 372: 130-131. PMID 33833111 DOI: 10.1126/science.abd1329  0.136
2015 Wang RS, Chang HY, Kao SH, Kao CH, Wu YC, Yeh S, Tzeng CR, Chang C. Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice. International Journal of Molecular Sciences. 16: 9831-49. PMID 25941928 DOI: 10.3390/Ijms16059831  0.135
2014 Liang CJ, Chang YC, Chang HC, Wang CK, Hung YC, Lin YE, Chan CC, Chen CH, Chang HY, Sang TK. Derlin-1 regulates mutant VCP-linked pathogenesis and endoplasmic reticulum stress-induced apoptosis. Plos Genetics. 10: e1004675. PMID 25255315 DOI: 10.1371/Journal.Pgen.1004675  0.135
2015 Chung SY, Kao CH, Villarroya F, Chang HY, Chang HC, Hsiao SP, Liou GG, Chen SL. Bhlhe40 Represses PGC-1α Activity on Metabolic Gene Promoters in Myogenic Cells. Molecular and Cellular Biology. 35: 2518-29. PMID 25963661 DOI: 10.1128/MCB.00387-15  0.134
2015 Lin CJ, Lien HM, Lin HJ, Huang CL, Kao MC, Chen YA, Wang CK, Chang HY, Chang YK, Wu HS, Lai CH. Modulation of T cell response by Phellinus linteus. Journal of Bioscience and Bioengineering. PMID 26092448 DOI: 10.1016/j.jbiosc.2015.05.008  0.134
2015 Chang HY, Li MH, Huang TC, Hsu CL, Tsai SR, Lee SC, Huang HC, Juan HF. Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells. Journal of Proteome Research. 14: 1250-62. PMID 25556991 DOI: 10.1021/pr5011873  0.131
2021 Granja JM, Corces MR, Pierce SE, Bagdatli ST, Choudhry H, Chang HY, Greenleaf WJ. Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis. Nature Genetics. PMID 33790476 DOI: 10.1038/s41588-021-00850-x  0.129
2015 Chang HY, Liao CY, Su GC, Lin SW, Wang HW, Chi P. Functional Relationship of ATP Hydrolysis, Presynaptic Filament Stability, and Homologous DNA Pairing Activity of the Human Meiotic Recombinase DMC1. The Journal of Biological Chemistry. PMID 26088134 DOI: 10.1074/jbc.M115.666289  0.127
2011 Chang H. Howard chang: Gene regulation in time and space Journal of Cell Biology. 195: 4-5. PMID 21969465 DOI: 10.1083/jcb.1951pi  0.125
2015 Lee HW, Chang DY, Moon HJ, Chang HY, Shin EC, Lee JS, Kim KA, Kim HJ. Clinical Factors and Viral Load Influencing Severity of Acute Hepatitis A. Plos One. 10: e0130728. PMID 26090677 DOI: 10.1371/journal.pone.0130728  0.123
2015 Kempen PJ, Greasley S, Parker KA, Campbell JL, Chang HY, Jones JR, Sinclair R, Gambhir SS, Jokerst JV. Theranostic mesoporous silica nanoparticles biodegrade after pro-survival drug delivery and ultrasound/magnetic resonance imaging of stem cells. Theranostics. 5: 631-42. PMID 25825602 DOI: 10.7150/Thno.11389  0.123
1997 Jay DG, Wang FS, Chang HY, Sydor AM, Liao JC. Chromophore assisted laser inactivation of cellular proteins Proceedings of Spie - the International Society For Optical Engineering. 2983: 30-36. DOI: 10.1117/12.274336  0.123
2022 Labanieh L, Majzner RG, Klysz D, Sotillo E, Fisher CJ, Vilches-Moure JG, Pacheco KZB, Malipatlolla M, Xu P, Hui JH, Murty T, Theruvath J, Mehta N, Yamada-Hunter SA, Weber EW, ... ... Chang HY, et al. Enhanced safety and efficacy of protease-regulated CAR-T cell receptors. Cell. PMID 35483375 DOI: 10.1016/j.cell.2022.03.041  0.12
2021 Smith JP, Corces MR, Xu J, Reuter VP, Chang HY, Sheffield NC. PEPATAC: an optimized pipeline for ATAC-seq data analysis with serial alignments. Nar Genomics and Bioinformatics. 3: lqab101. PMID 34859208 DOI: 10.1093/nargab/lqab101  0.12
2014 Santra TS, Chang HY, Wang PC, Tseng FG. Impact of pulse duration on localized single-cell nano-electroporation. The Analyst. 139: 6249-58. PMID 25320952 DOI: 10.1039/C4An01050G  0.12
2016 Chang HY, Kao WL, You YW, Chu YH, Chu KJ, Chen PJ, Wu CY, Lee YH, Shyue JJ. Effect of surface potential on epithelial cell adhesion, proliferation and morphology. Colloids and Surfaces. B, Biointerfaces. 141: 179-186. PMID 26852101 DOI: 10.1016/J.Colsurfb.2016.01.049  0.115
2015 Mitchell A, Chang HY, Daugherty L, Fraser M, Hunter S, Lopez R, McAnulla C, McMenamin C, Nuka G, Pesseat S, Sangrador-Vegas A, Scheremetjew M, Rato C, Yong SY, Bateman A, et al. The InterPro protein families database: the classification resource after 15 years. Nucleic Acids Research. 43: D213-21. PMID 25428371 DOI: 10.1093/Nar/Gku1243  0.114
2014 Ding YZ, You YN, Sun DJ, Chen HT, Wang YL, Chang HY, Pan L, Fang YZ, Zhang ZW, Zhou P, Lv JL, Liu XS, Shao JJ, Zhao FR, Lin T, et al. The effects of the context-dependent codon usage bias on the structure of the nsp1α of porcine reproductive and respiratory syndrome virus. Biomed Research International. 2014: 765320. PMID 25162025 DOI: 10.1155/2014/765320  0.112
2014 Chang HY, You YW, Liao HY, Shyue JJ. Binary self-assembled monolayers modified Au nanoparticles as carriers in biological applications. Biointerphases. 9: 041005. PMID 25553880 DOI: 10.1116/1.4903934  0.109
2014 Kim KH, Chang HY, Park JY, Park ES, Park YK, Han KH, Ahn SH. Spontaneous HBsAg loss in Korean patients: relevance of viral genotypes, S gene mutations, and covalently closed circular DNA copy numbers. Clinical and Molecular Hepatology. 20: 251-60. PMID 25320728 DOI: 10.3350/cmh.2014.20.3.251  0.106
2015 Mateja A, Paduch M, Chang HY, Szydlowska A, Kossiakoff AA, Hegde RS, Keenan RJ. Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science (New York, N.Y.). 347: 1152-5. PMID 25745174 DOI: 10.1126/Science.1261671  0.105
2015 Sheen JM, Yu HR, Tiao MM, Chen CC, Huang LT, Chang HY, Tain YL. Prenatal dexamethasone-induced programmed hypertension and renal programming. Life Sciences. 132: 41-8. PMID 25921765 DOI: 10.1016/J.Lfs.2015.04.005  0.101
2015 Lee YC, Lin SW, Chen MY, Chang SY, Kuo CH, Sheng WH, Hsieh SM, Sun HY, Chang HY, Wu MR, Liu WC, Wu PY, Yang SP, Zhang JY, Su YC, et al. Presence of Tablet Remnants of Nevirapine Extended-Release in Stools and Its Impact on Virological Outcome in HIV-1-Infected Patients: A Prospective Cohort Study. Plos One. 10: e0140574. PMID 26465325 DOI: 10.1371/journal.pone.0140574  0.1
2015 Shinoda K, Ohyama K, Hasegawa Y, Chang HY, Ogura M, Sato A, Hong H, Hosono T, Sharp LZ, Scheel DW, Graham M, Ishihama Y, Kajimura S. Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure. Cell Metabolism. PMID 26525534 DOI: 10.1016/J.Cmet.2015.09.029  0.099
2015 Dong GC, Kuan CY, Subramaniam S, Zhao JY, Sivasubramaniam S, Chang HY, Lin FH. A potent inhibition of oxidative stress induced gene expression in neural cells by sustained ferulic acid release from chitosan based hydrogel. Materials Science & Engineering. C, Materials For Biological Applications. 49: 691-9. PMID 25686998 DOI: 10.1016/j.msec.2015.01.030  0.098
2020 Lee H, Chang HY, Cho SW, Ji HP. CRISPRpic: fast and precise analysis for CRISPR-induced mutations via prefixed index counting. Nar Genomics and Bioinformatics. 2: lqaa012. PMID 32118203 DOI: 10.1093/nargab/lqaa012  0.098
2015 Kao PM, Hsu BM, Hsu TK, Liu JH, Chang HY, Ji WT, Tzeng KJ, Huang SW, Huang YL. Seasonal distribution of potentially pathogenic Acanthamoeba species from drinking water reservoirs in Taiwan. Environmental Science and Pollution Research International. 22: 3766-73. PMID 25263419 DOI: 10.1007/S11356-014-3651-8  0.098
2020 Sun YV, Liu C, Staimez L, Ali MK, Chang H, Kondal D, Patel S, Jones D, Mohan V, Tandon N, Prabhakaran D, Quyyumi AA, Narayan KMV, Agrawal A. Cardiovascular disease risk and pathophysiology in South Asians: can longitudinal multi-omics shed light? Wellcome Open Research. 5: 255. PMID 34136649 DOI: 10.12688/wellcomeopenres.16336.2  0.097
2015 Tsai KW, Li GC, Chen CH, Yeh MH, Huang JS, Tseng HH, Fu TY, Liou HH, Pan HW, Huang SF, Chen CC, Chang HY, Ger LP, Chang HT. Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype. Breast Cancer Research and Treatment. PMID 26253945 DOI: 10.1007/s10549-015-3525-x  0.096
2015 Choong WK, Chang HY, Chen CT, Tsai CF, Hsu WL, Chen YJ, Sung TY. Informatics view on the challenges of identifying missing proteins from shotgun proteomics. Journal of Proteome Research. PMID 26549055 DOI: 10.1021/Acs.Jproteome.5B00482  0.095
2015 Wang RS, Chang HY, Kao SH, Kao CH, Wu YC, Yeh S, Tzeng CR, Chang C. Abnormal mitochondrial function and impaired granulosa cell differentiation in androgen receptor knockout mice International Journal of Molecular Sciences. 16: 9831-9849. DOI: 10.3390/ijms16059831  0.095
2015 Chen PY, Wu MJ, Chang HY, Tai MH, Ho CT, Yen JH. Up-Regulation of miR-34a Expression in Response to the Luteolin-Induced Neurite Outgrowth of PC12 Cells. Journal of Agricultural and Food Chemistry. 63: 4148-59. PMID 25865700 DOI: 10.1021/Acs.Jafc.5B01005  0.092
2014 Lee E, Chang HY, Lee KS, Suh DI, Yu HS, Kang MJ, Choi IA, Park J, Kim KW, Shin YH, Ahn KM, Kwon JY, Choi SJ, Lee KJ, Won HS, et al. The effect of perinatal anxiety on bronchiolitis is influenced by polymorphisms in ROS-related genes. Bmc Pulmonary Medicine. 14: 154. PMID 25263840 DOI: 10.1186/1471-2466-14-154  0.089
2015 Chung CJ, Chang CH, Chuu CP, Yang CR, Chang YH, Huang CP, Chen WC, Chung MC, Chang H. Reduced 5-methylcytosine level as a potential progression predictor in patients with T1 or non-invasive urothelial carcinoma. International Journal of Molecular Sciences. 16: 677-90. PMID 25561224 DOI: 10.3390/Ijms16010677  0.087
2016 Chen CY, Kao AL, Tsai ZC, Chow TJ, Chang HY, Zhao XQ, Chen PT, Su HY, Chang JS. Expression of type 2 diacylglycerol acyltransferse gene DGTT1 from Chlamydomonas reinhardtii enhances lipid production in Scenedesmus obliquus. Biotechnology Journal. PMID 26849021 DOI: 10.1002/biot.201500272  0.086
2016 Santra TS, Chen CW, Chang HY, Tseng FG. Dielectric passivation layer as a substratum on localized single-cell electroporation Rsc Advances. 6: 10979-10986. DOI: 10.1039/c5ra18258a  0.085
2017 Wei H, Chang H, Zheng L, Lin S, Chen Y, Tian H, Zhao J, Chen Y, Cai H, Gu X, Murugan K. Identification and expression profiling of pheromone biosynthesis activating neuropeptide in Chlumetia transversa (Walker). Pesticide Biochemistry and Physiology. 135: 89-96. PMID 28043337 DOI: 10.1016/j.pestbp.2016.05.005  0.083
2009 Emtage L, Chang H, Tiver R, Rongo C. MAGI-1 modulates AMPA receptor synaptic localization and behavioral plasticity in response to prior experience. Plos One. 4: e4613. PMID 19242552 DOI: 10.1371/Journal.Pone.0004613  0.082
2021 Griffin MF, Borrelli MR, Garcia JT, Januszyk M, King M, Lerbs T, Cui L, Moore AL, Shen AH, Mascharak S, Diaz Deleon NM, Adem S, Taylor WL, desJardins-Park HE, Gastou M, ... ... Chang HY, et al. JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models. Science Translational Medicine. 13: eabb3312. PMID 34516825 DOI: 10.1126/scitranslmed.abb3312  0.081
2015 Chang HY, Keyes KM, Mok Y, Jung KJ, Shin YJ, Jee SH. Depression as a risk factor for overall and hormone-related cancer: the Korean cancer prevention study. Journal of Affective Disorders. 173: 1-8. PMID 25462388 DOI: 10.1016/J.Jad.2014.10.064  0.079
2015 Hussain T, Chang HY, Veenstra CM, Pollack CE. Collaboration Between Surgeons and Medical Oncologists and Outcomes for Patients With Stage III Colon Cancer. Journal of Oncology Practice / American Society of Clinical Oncology. 11: e388-97. PMID 25873063 DOI: 10.1200/JOP.2014.003293  0.078
1993 Wang TC, Chang HY, Hung JL. Cosuppression of recF, recR and recO mutations by mutant recA alleles in Escherichia coli cells. Mutation Research. 294: 157-66. PMID 7687008 DOI: 10.1016/0921-8777(93)90024-B  0.078
2021 Chang HY. Personal regulome navigation of cancer. Nature Reviews. Cancer. PMID 34172966 DOI: 10.1038/s41568-021-00381-x  0.077
2015 Chen LY, Wu PH, Guan HH, Fun HK, Chang HY, Chen CJ. Purification, crystallization and preliminary X-ray crystallographic analysis of the phosphatase domain (PA3346PD) of the response regulator PA3346 from Pseudomonas aeruginosa PAO1. Acta Crystallographica. Section F, Structural Biology Communications. 71: 434-7. PMID 25849505 DOI: 10.1107/S2053230X15004197  0.077
2016 Lin WC, Chang HY, Chen JY. Electrotransfer of the tilapia piscidin 3 and tilapia piscidin 4 genes into skeletal muscle enhances the antibacterial and immunomodulatory functions of Oreochromis niloticus. Fish & Shellfish Immunology. PMID 26828260 DOI: 10.1016/j.fsi.2016.01.034  0.077
2016 Chang H, Ashu E, Sharma C, Kathuria S, Chowdhary A, Xu J. Diversity and origins of Indian multi-triazole resistant strains of Aspergillus fumigatus. Mycoses. PMID 26931802 DOI: 10.1111/Myc.12494  0.072
2023 Collins JE, Lee JW, Rocamora F, Saggu GS, Wendt KL, Pasaje CFA, Smick S, Santos NM, Paes R, Jiang T, Mittal N, Luth MR, Chin T, Chang H, McLellan JL, et al. Antiplasmodial peptaibols act through membrane directed mechanisms. Cell Chemical Biology. PMID 37995692 DOI: 10.1016/j.chembiol.2023.10.025  0.069
2015 Lee HW, Lee SH, Lee MG, Ahn SH, Chang HY, Han KH. The clinical implication of single nucleotide polymorphisms in deoxycytidine kinase in chronic hepatitis B patients treated with lamivudine. Journal of Medical Virology. PMID 26400223 DOI: 10.1002/jmv.24393  0.069
2015 Hussain T, Chang HY, Veenstra CM, Pollack CE. Fragmentation in specialist care and stage III colon cancer. Cancer. PMID 26043368 DOI: 10.1002/cncr.29474  0.069
2015 Chang HY, Lee HN, Kim W, Surh YJ. Docosahexaenoic acid induces M2 macrophage polarization through peroxisome proliferator-activated receptor γ activation. Life Sciences. 120: 39-47. PMID 25445227 DOI: 10.1016/j.lfs.2014.10.014  0.069
2014 Yang SC, Lai WW, Chang HY, Su WC, Chen HH, Wang JD. Estimation of loss of quality-adjusted life expectancy (QALE) for patients with operable versus inoperable lung cancer: adjusting quality-of-life and lead-time bias for utility of surgery. Lung Cancer (Amsterdam, Netherlands). 86: 96-101. PMID 25178685 DOI: 10.1016/j.lungcan.2014.08.006  0.067
2015 Chiang CY, Pan CC, Chang HY, Lai MD, Tzai TS, Tsai YS, Ling P, Liu HS, Lee BF, Cheng HL, Ho CL, Chen SH, Chow NH. SH3BGRL3 Protein As A Potential Prognostic Biomarker For Urothelial Carcinoma: A novel binding partner of epidermal growth factor receptor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26286913 DOI: 10.1158/1078-0432.CCR-14-3308  0.066
2008 Gallicchio L, Chang H, Christo DK, Thuita L, Huang HY, Strickland P, Ruczinski I, Hoffman SC, Helzlsouer KJ. Single nucleotide polymorphisms in inflammation-related genes and mortality in a community-based cohort in Washington County, Maryland. American Journal of Epidemiology. 167: 807-13. PMID 18263601 DOI: 10.1093/Aje/Kwm378  0.066
2014 Kim JK, Lee KS, Lee DK, Lee SY, Chang HY, Choi J, Lee JI. Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice. Experimental & Molecular Medicine. 46: e127. PMID 25523099 DOI: 10.1038/emm.2014.90  0.065
2015 Chou HC, Wang YM, Chang HY. Design intelligent wheelchair with ECG measurement and wireless transmission function. Technology and Health Care : Official Journal of the European Society For Engineering and Medicine. PMID 26444818 DOI: 10.3233/THC-151092  0.063
2016 Chen CW, Chang HY, Chen JH, Weng R. Elucidating the role of conformity in innovative smartphones International Journal of Mobile Communications. 14: 56-78. DOI: 10.1504/IJMC.2016.073367  0.063
2006 Chen CC, Shieh DB, Shih TS, Tai HM, Chang HY. Mitochondrial DNA Damage in Humans Occupationally Exposed to N,N-dimethylformamide Epidemiology. 17: S510. DOI: 10.1097/00001648-200611001-01372  0.062
2018 Henneman LRF, Liu C, Chang H, Mulholland J, Tolbert P, Russell A. Air quality accountability: Developing long-term daily time series of pollutant changes and uncertainties in Atlanta, Georgia resulting from the 1990 Clean Air Act Amendments. Environment International. 123: 522-534. PMID 30622077 DOI: 10.1016/J.Envint.2018.12.028  0.061
2021 Zhang Y, Shi L, Chang H, Schwartz J, Di Q, Goldberg J, Vaccarino V. A Co-Twin control study of fine particulate matter and the prevalence of metabolic syndrome risk factors. Environmental Research. 111604. PMID 34186076 DOI: 10.1016/j.envres.2021.111604  0.061
2016 Chang HY, Chen CT, Lih TM, Lynn KS, Juo CG, Hsu WL, Sung TY. iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination. Plos One. 11: e0146112. PMID 26784691 DOI: 10.1371/Journal.Pone.0146112  0.06
2023 Spencer RK, Elhage KG, Jin JQ, Davis MS, Hakimi M, Bhutani T, Chang H, Liao W. Living with Psoriasis Vulgaris and Multi-Treatment Failure: A Patient and Dermatologist Perspective. Dermatology and Therapy. 13: 857-866. PMID 36913122 DOI: 10.1007/s13555-023-00907-1  0.059
2004 Burkhart CN, Chang H, Gottwald L. Tinea corporis in human immunodeficiency virus-positive patients: case report and assessment of oral therapy. International Journal of Dermatology. 42: 839-43. PMID 14521706 DOI: 10.1046/j.1365-4362.2003.01894.x  0.059
2015 Lee HW, Kwon JC, Oh IS, Chang HY, Cha YJ, Choi IS, Kim HJ. Prolonged Entecavir Therapy is not Effective for HBeAg Seroconversion in Treatment-Naive Chronic Hepatitis B Patients with a Partial Virological Response. Antimicrobial Agents and Chemotherapy. PMID 26100697 DOI: 10.1128/AAC.01017-15  0.059
2016 Chang HY, Yang XK, Chhetri PM, Chen CH, Liu YF, Chen JD. Structure-directing roles of phenylenediacetate ligands in the formation of N,N′-di(3-pyridyl)adipoamide-based coordination networks Polyhedron. 106: 32-39. DOI: 10.1016/j.poly.2015.12.046  0.057
2014 Ge T, Qin H, Wang X, Yang SS, Guo L, Han W, Chang HY. Effects of thoracic epidural anesthesia on cardiac function and myocardial cell apoptosis in isoproterenol-induced chronic heart failure rats. Journal of Interventional Cardiology. 27: 446-55. PMID 25267251 DOI: 10.1111/joic.12147  0.056
2015 Chang HY, Huang MF, Hsu CL, Huang CC, Chang HT. Analyses of functional polymer-modified nanoparticles for protein sensing by surface-assisted laser desorption/ionization mass spectrometry coupled with HgTe nanomatrices. Colloids and Surfaces. B, Biointerfaces. 130: 157-63. PMID 25896538 DOI: 10.1016/j.colsurfb.2015.04.001  0.054
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