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Jonathan L. Haines, PhD - Publications

Affiliations: 
Molecular Physiology and Biophysics Vanderbilt University, Nashville, TN 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=95
Website:
http://kc.vanderbilt.edu/site/people/1461/haines-jonathan.aspx

324 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Gardner OK, Van Booven D, Wang L, Gu T, Hofmann NK, Whitehead PL, Nuytemans K, Hamilton-Nelson KL, Adams LD, Starks TD, Cuccaro ML, Martin ER, Vance JM, Bush WS, Byrd GS, ... Haines JL, et al. Genetic Architecture of RNA Editing Regulation in Alzheimer Disease across Diverse Ancestral Populations. Human Molecular Genetics. PMID 35383839 DOI: 10.1093/hmg/ddac075  0.56
2022 Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Haines JL, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z  0.599
2022 Vardarajan BN, Reyes-Dumeyer D, Piriz AL, Lantigua RA, Medrano M, Rivera D, Jiménez-Velázquez IZ, Martin E, Pericak-Vance MA, Bush W, Farrer L, Haines JL, Wang LS, Leung YY, Schellenberg G, et al. Progranulin mutations in clinical and neuropathological Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35258170 DOI: 10.1002/alz.12567  0.497
2022 Jin B, Capra JA, Benchek P, Wheeler NR, Naj AC, Hamilton-Nelson KL, Farrell JJ, Leung YY, Kunkle BW, Vardarajan BN, Schellenberg GD, Mayeux R, Wang LS, Farrer LA, Pericak-Vance M, ... ... Haines JL, et al. An association test of the spatial distribution of rare missense variants within protein structures identify Alzheimer's disease-related patterns. Genome Research. PMID 35210353 DOI: 10.1101/gr.276069.121  0.6
2022 Shade LM, Katsumata Y, Hohman TJ, Nho K, Saykin AJ, Mukherjee S, Boehme KL, Kauwe JS, Farrer LA, Schellenberg GD, Haines JL, Mayeux RP, Schneider JA, Nelson PT, Fardo DW. Genome-wide association study of brain arteriolosclerosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211066299. PMID 35156446 DOI: 10.1177/0271678X211066299  0.304
2021 Xue D, Bush WS, Renton AE, Marcora EA, Bis JC, Kunkle BW, Boerwinkle E, DeStefano AL, Farrer L, Goate A, Mayeux R, Pericak-Vance M, Schellenberg G, Seshadri S, ... ... Haines JL, et al. Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12255. PMID 35005195 DOI: 10.1002/dad2.12255  0.592
2021 Rajabli F, Feliciano-Astacio BE, Cukier HN, Wang L, Griswold AJ, Hamilton-Nelson KL, Adams LD, Rodriguez VC, Mena PR, Tejada S, Celis K, Whitehead PL, Van Booven DJ, Hofmann NK, Bussies PL, ... ... Haines JL, et al. Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus. Neurobiology of Aging. PMID 33902942 DOI: 10.1016/j.neurobiolaging.2021.02.019  0.367
2021 Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segrè AV, Rouhana JM, Hamel AR, Igo RP, Choquet H, Qassim A, Josyula NS, ... ... Haines JL, et al. Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications. 12: 1258. PMID 33627673 DOI: 10.1038/s41467-020-20851-4  0.379
2020 Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, ... ... Haines JL, et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/Brain/Awaa209  0.605
2020 Griswold AJ, Sivasankaran SK, Van Booven D, Gardner OK, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Adams LD, Scott AM, Hofmann NK, Vance JM, Cuccaro ML, Bush WS, Martin ER, Byrd GS, ... Haines JL, et al. Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort. Journal of Alzheimer's Disease : Jad. PMID 32597797 DOI: 10.3233/Jad-190855  0.577
2020 Wheeler NR, Benchek P, Kunkle BW, Hamilton-Nelson KL, Warfe M, Fondran JR, Haines JL, Bush WS. Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 25: 523-534. PMID 31797624  0.546
2019 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Haines JL, et al. Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 31636380 DOI: 10.1038/s41380-019-0529-7  0.53
2019 Waksmunski AR, Grunin M, Kinzy TG, Igo RP, Haines JL, Cooke Bailey JN. Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 60: 4041-4051. PMID 31560769 DOI: 10.1167/iovs.19-27827  0.338
2019 Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, ... ... Haines JL, et al. Sex differences in the genetic predictors of Alzheimer's pathology. Brain : a Journal of Neurology. 142: 2581-2589. PMID 31497858 DOI: 10.1093/Brain/Awz206  0.607
2019 Fan BJ, Bailey JC, Igo RP, Kang JH, Boumenna T, Brilliant MH, Budenz DL, Fingert JH, Gaasterland T, Gaasterland D, Hauser MA, Kraft P, Lee RK, Lichter PR, Liu Y, ... ... Haines JL, et al. Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis. Jama Ophthalmology. PMID 31436842 DOI: 10.1001/Jamaophthalmol.2019.3109  0.314
2019 Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, ... ... Haines JL, et al. Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of ε4 on Alzheimer's Disease Risk in a Multiracial Sample. Journal of Clinical Medicine. 8. PMID 31426376 DOI: 10.3390/Jcm8081236  0.302
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Haines JL, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.561
2019 Waksmunski AR, Igo RP, Song YE, Cooke Bailey JN, Laux R, Fuzzell D, Fuzzell S, Adams LD, Caywood L, Prough M, Stambolian D, Scott WK, Pericak-Vance MA, Haines JL. Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish. Human Genetics. PMID 31367973 DOI: 10.1007/S00439-019-02050-4  0.425
2019 Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW, Bis JC, Debette S, DeStefano AL, Fornage M, Nicolas G, ... ... Haines JL, et al. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. Jama Neurology. PMID 31180460 DOI: 10.1001/Jamaneurol.2019.1456  0.343
2019 Gardner OK, Wang L, Van Booven D, Whitehead PL, Hamilton-Nelson KL, Adams LD, Starks TD, Hofmann NK, Vance JM, Cuccaro ML, Martin ER, Byrd GS, Haines JL, Bush WS, Beecham GW, et al. RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways. Human Molecular Genetics. PMID 31162550 DOI: 10.1093/Hmg/Ddz110  0.525
2019 Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, et al. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. e12964. PMID 31144443 DOI: 10.1111/Acel.12964  0.324
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Haines JL, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.624
2018 Beecham GW, Vardarajan B, Blue E, Bush W, Jaworski J, Barral S, DeStefano A, Hamilton-Nelson K, Kunkle B, Martin ER, Naj A, Rajabli F, Reitz C, Thornton T, van Duijn C, ... ... Haines JL, et al. Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease. Neurology. Genetics. 4: e286. PMID 30569016 DOI: 10.1212/Nxg.0000000000000286  0.591
2018 Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, ... ... Haines JL, et al. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathologica. PMID 30413934 DOI: 10.1007/S00401-018-1928-6  0.342
2018 Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, ... ... Haines JL, et al. Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. Neurobiology of Aging. PMID 30201328 DOI: 10.1016/J.Neurobiolaging.2018.08.001  0.339
2018 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Haines JL, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7  0.631
2018 Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, ... ... Haines JL, et al. Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathologica. PMID 29967939 DOI: 10.1007/s00401-018-1881-4  0.569
2018 Fan BJ, Chen X, Sondhi N, Sharmila PF, Soumittra N, Sripriya S, Sacikala S, Asokan R, Friedman DS, Pasquale LR, Gao XR, Vijaya L, Cooke Bailey J, Vitart V, MacGregor S, ... ... Haines JL, et al. Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus. Investigative Ophthalmology & Visual Science. 59: 2495-2502. PMID 29847655 DOI: 10.1167/Iovs.17-23536  0.303
2018 Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, ... ... Haines JL, et al. Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau. Jama Neurology. PMID 29801024 DOI: 10.1001/Jamaneurol.2018.0821  0.562
2018 Iglesias AI, Mishra A, Vitart V, Bykhovskaya Y, Höhn R, Springelkamp H, Cuellar-Partida G, Gharahkhani P, Bailey JNC, Willoughby CE, Li X, Yazar S, Nag A, Khawaja AP, Polašek O, ... ... Haines JL, et al. Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nature Communications. 9: 1864. PMID 29760442 DOI: 10.1038/S41467-018-03646-6  0.334
2018 Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj A, Thornton T, DeStefano A, Martin E, Wang LS, Brown L, ... ... Haines JL, et al. Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. 5: 406-417. PMID 29688227 DOI: 10.1002/Acn3.537  0.584
2018 Lancour D, Naj A, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GC, Crovella M, Farrer LA, Kasif S. One for all and all for One: Improving replication of genetic studies through network diffusion. Plos Genetics. 14: e1007306. PMID 29684019 DOI: 10.1371/Journal.Pgen.1007306  0.31
2018 Butkiewicz M, Blue E, Leung F, Jian X, Marcora E, Renton A, Kuzma A, Wang LS, Koboldt D, Haines JL, Bush WS. Functional Annotation of genomic variants in studies of Late-Onset Alzheimer's Disease. Bioinformatics (Oxford, England). PMID 29590295 DOI: 10.1093/Bioinformatics/Bty177  0.597
2018 Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, et al. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dementia and Geriatric Cognitive Disorders. 45: 1-17. PMID 29486463 DOI: 10.1159/000485503  0.573
2018 Shiga Y, Akiyama M, Nishiguchi KM, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Koichi M, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, ... ... Haines JL, et al. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Human Molecular Genetics. PMID 29452408 DOI: 10.1093/Hmg/Ddy053  0.399
2018 Gharahkhani P, Burdon KP, Cooke Bailey JN, Hewitt AW, Law MH, Pasquale LR, Kang JH, Haines JL, Souzeau E, Zhou T, Siggs OM, Landers J, Awadalla M, Sharma S, Mills RA, et al. Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. Scientific Reports. 8: 3124. PMID 29449654 DOI: 10.1038/S41598-018-20435-9  0.355
2017 Persad PJ, Heid IM, Weeks DE, Baird PN, de Jong EK, Haines JL, Pericak-Vance MA, Scott WK. Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1. Investigative Ophthalmology & Visual Science. 58: 4027-4038. PMID 28813576 DOI: 10.1167/Iovs.17-21734  0.321
2017 Hou L, Kember RL, Roach JC, O'Connell JR, Craig DW, Bucan M, Scott WK, Pericak-Vance M, Haines JL, Crawford MH, Shuldiner AR, McMahon FJ. A population-specific reference panel empowers genetic studies of Anabaptist populations. Scientific Reports. 7: 6079. PMID 28729679 DOI: 10.1038/S41598-017-05445-3  0.313
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Haines JL, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.349
2017 Aung T, Ozaki M, Lee MC, Schlötzer-Schrehardt U, Thorleifsson G, Mizoguchi T, Igo RP, Haripriya A, Williams SE, Astakhov YS, Orr AC, Burdon KP, Nakano S, Mori K, Abu-Amero K, ... ... Haines JL, et al. Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Nature Genetics. PMID 28553957 DOI: 10.1038/Ng.3875  0.383
2017 Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, ... ... Haines JL, et al. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. Plos Medicine. 14: e1002258. PMID 28323831 DOI: 10.1371/Journal.Pmed.1002258  0.325
2017 Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, ... ... Haines JL, et al. Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers. Acta Neuropathologica. PMID 28247064 DOI: 10.1007/s00401-017-1685-y  0.344
2017 Butkiewicz M, Haines JL, Bush WS. Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants. Bioinformatics (Oxford, England). PMID 28122779 DOI: 10.1093/Bioinformatics/Btw820  0.548
2016 Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, ... ... Haines JL, et al. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27770636 DOI: 10.1016/J.Jalz.2016.09.002  0.385
2016 Verma SS, Cooke Bailey JN, Lucas A, Bradford Y, Linneman JG, Hauser MA, Pasquale LR, Peissig PL, Brilliant MH, McCarty CA, Haines JL, Wiggs JL, Vrabec TR, Tromp G, Ritchie MD, et al. Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. Plos Genetics. 12: e1006186. PMID 27623284 DOI: 10.1371/Journal.Pgen.1006186  0.579
2016 Butkiewicz M, Cooke Bailey JN, Frase A, Dudek S, Yaspan BL, Ritchie MD, Pendergrass SA, Haines JL. Pathway analysis by randomization incorporating structure-PARIS: an update. Bioinformatics (Oxford, England). PMID 27153576 DOI: 10.1093/Bioinformatics/Btw130  0.469
2016 Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JS. Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiology of Aging. PMID 27036079 DOI: 10.1016/J.Neurobiolaging.2016.02.024  0.334
2016 Cooke Bailey JN, Hoffman JD, Sardell RJ, Scott WK, Pericak-Vance MA, Haines JL. The Application of Genetic Risk Scores in Age-Related Macular Degeneration: A Review. Journal of Clinical Medicine. 5. PMID 26959068 DOI: 10.3390/Jcm5030031  0.366
2016 Bush WS, Crosslin DR, Obeng AO, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, ... ... Haines JL, et al. Genetic Variation among 82 Pharmacogenes: the PGRN-Seq data from the eMERGE Network. Clinical Pharmacology and Therapeutics. PMID 26857349 DOI: 10.1002/Cpt.350  0.663
2016 Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, ... Haines JL, et al. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiology of Aging. 38: 141-50. PMID 26827652 DOI: 10.1016/J.Neurobiolaging.2015.10.031  0.711
2016 Bailey JN, Loomis SJ, Kang JH, Allingham RR, Gharahkhani P, Khor CC, Burdon KP, Aschard H, Chasman DI, Igo RP, Hysi PG, Glastonbury CA, Ashley-Koch A, Brilliant M, Brown AA, ... ... Haines JL, et al. Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. Nature Genetics. PMID 26752265 DOI: 10.1038/Ng.3482  0.538
2016 Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, ... ... Haines JL, et al. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nature Genetics. 48: 134-43. PMID 26691988 DOI: 10.1038/Ng.3448  0.478
2015 Hall JB, Cooke Bailey JN, Hoffman JD, Pericak-Vance MA, Scott WK, Kovach JL, Schwartz SG, Agarwal A, Brantley MA, Haines JL, Bush WS. Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models. Bmc Bioinformatics. 16: 329. PMID 26467978 DOI: 10.1186/S12859-015-0760-4  0.61
2015 Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA, Haines JL, Goate AM, Foroud T, Boerwinkle E, Schellenberg GD, et al. Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26433351 DOI: 10.1016/J.Jalz.2015.07.487  0.413
2015 Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, ... ... Haines JL, et al. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. Jama Neurology. PMID 26366463 DOI: 10.1001/Jamaneurol.2015.1700  0.301
2015 Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH, DeStefano AL, Carney RM, Cuccaro M, Vance JM, Farrer LA, ... ... Haines JL, et al. Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26365416 DOI: 10.1016/J.Jalz.2015.05.020  0.406
2015 Fan BJ, Pasquale LR, Kang JH, Levkovitch-Verbin H, Haines JL, Wiggs JL. Association of clusterin (CLU) variants and exfoliation syndrome: An analysis in two Caucasian studies and a meta-analysis. Experimental Eye Research. 139: 115-22. PMID 26272660 DOI: 10.1016/j.exer.2015.08.004  0.333
2015 Crawford DC, Goodloe R, Farber-Eger E, Boston J, Pendergrass SA, Haines JL, Ritchie MD, Bush WS. Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits. Human Heredity. 79: 137-46. PMID 26201699 DOI: 10.1159/000381805  0.63
2015 Griswold AJ, Dueker ND, Van Booven D, Rantus JA, Jaworski JM, Slifer SH, Schmidt MA, Hulme W, Konidari I, Whitehead PL, Cuccaro ML, Martin ER, Haines JL, Gilbert JR, Hussman JP, et al. Targeted massively parallel sequencing of autism spectrum disorder-associated genes in a case control cohort reveals rare loss-of-function risk variants. Molecular Autism. 6: 43. PMID 26185613 DOI: 10.1186/S13229-015-0034-Z  0.313
2015 Hall MA, Verma SS, Wallace J, Lucas A, Berg RL, Connolly J, Crawford DC, Crosslin DR, de Andrade M, Doheny KF, Haines JL, Harley JB, Jarvik GP, Kitchner T, Kuivaniemi H, et al. Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network. Genetic Epidemiology. 39: 376-84. PMID 25982363 DOI: 10.1002/Gepi.21902  0.543
2015 Li Z, Allingham RR, Nakano M, Jia L, Chen Y, Ikeda Y, Mani B, Chen LJ, Kee C, Garway-Heath DF, Sripriya S, Fuse N, Abu-Amero KK, Huang C, Namburi P, ... ... Haines JL, et al. A common variant near TGFBR3 is associated with primary open angle glaucoma. Human Molecular Genetics. 24: 3880-92. PMID 25861811 DOI: 10.1093/Hmg/Ddv128  0.339
2015 Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, ... ... Haines JL, et al. A novel Alzheimer disease locus located near the gene encoding tau protein. Molecular Psychiatry. PMID 25778476 DOI: 10.1038/Mp.2015.23  0.355
2015 Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, ... ... Haines JL, et al. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Molecular Psychiatry. PMID 25687773 DOI: 10.1038/Mp.2015.6  0.313
2015 D'Aoust LN, Cummings AC, Laux R, Fuzzell D, Caywood L, Reinhart-Mercer L, Scott WK, Pericak-Vance MA, Haines JL. Examination of candidate exonic variants for association to Alzheimer disease in the Amish. Plos One. 10: e0118043. PMID 25668194 DOI: 10.1371/Journal.Pone.0118043  0.713
2015 Restrepo NA, Mitchell SL, Goodloe RJ, Murdock DG, Haines JL, Crawford DC. Mitochondrial variation and the risk of age-related macular degeneration across diverse populations. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 243-54. PMID 25592585  0.304
2015 Hall JB, Cooke Bailey JN, Hoffman JD, Pericak-Vance MA, Scott WK, Kovach JL, Schwartz SG, Agarwal A, Brantley MA, Haines JL, Bush WS. Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models Bmc Bioinformatics. 16. DOI: 10.1186/s12859-015-0760-4  0.497
2014 Bush WS, Haines JL. Genotype Correlation Analysis Reveals Pathway-Based Functional Disequilibrium and Potential Epistasis in the Human Interactome. Applications of Evolutionary Computation : 17th European Conference, Evoapplications 2014, Granada, Spain, April 23-25, 2014 : Revised Selected Papers. Evoapplications (Conference) (17th : 2014 : Granada, Spain). 8602: 890-901. PMID 28393142 DOI: 10.1007/978-3-662-45523-4_72  0.593
2014 Verma SS, de Andrade M, Tromp G, Kuivaniemi H, Pugh E, Namjou-Khales B, Mukherjee S, Jarvik GP, Kottyan LC, Burt A, Bradford Y, Armstrong GD, Derr K, Crawford DC, Haines JL, et al. Imputation and quality control steps for combining multiple genome-wide datasets. Frontiers in Genetics. 5: 370. PMID 25566314 DOI: 10.3389/Fgene.2014.00370  0.521
2014 Allen M, Kachadoorian M, Quicksall Z, Zou F, Chai HS, Younkin C, Crook JE, Pankratz VS, Carrasquillo MM, Krishnan S, Nguyen T, Ma L, Malphrus K, Lincoln S, Bisceglio G, ... ... Haines JL, et al. Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels. Alzheimer's Research & Therapy. 6: 39. PMID 25324900 DOI: 10.1186/Alzrt268  0.303
2014 Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, ... ... Haines JL, et al. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nature Communications. 5: 4883. PMID 25241763 DOI: 10.1038/ncomms5883  0.311
2014 Cooke Bailey JN, Pericak-Vance MA, Haines JL. Genome-wide association studies: getting to pathogenesis, the role of inflammation/complement in age-related macular degeneration. Cold Spring Harbor Perspectives in Medicine. 4: a017186. PMID 25213188 DOI: 10.1101/Cshperspect.A017186  0.454
2014 Restrepo NA, Spencer KL, Goodloe R, Garrett TA, Heiss G, Bůžková P, Jorgensen N, Jensen RA, Matise TC, Hindorff LA, Klein BE, Klein R, Wong TY, Cheng CY, Cornes BK, ... ... Haines JL, et al. Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. Investigative Ophthalmology & Visual Science. 55: 6839-50. PMID 25205864 DOI: 10.1167/Iovs.14-14246  0.711
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Haines JL, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.33
2014 Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, ... ... Haines JL, et al. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nature Genetics. 46: 1126-30. PMID 25173106 DOI: 10.1038/Ng.3087  0.362
2014 Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, et al. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Annals of Neurology. 76: 379-92. PMID 25043464 DOI: 10.1002/Ana.24219  0.398
2014 Bailey JN, Pericak-Vance MA, Haines JL. The impact of the human genome project on complex disease. Genes. 5: 518-35. PMID 25032678 DOI: 10.3390/Genes5030518  0.467
2014 Courtenay MD, Cade W, Schwartz SG, Kovach JL, Agarwal A, Wang G, Haines JL, Pericak-Vance MA, Scott WK. Set-based joint test of interaction between SNPs in the VEGF pathway and exogenous estrogen finds association with age-related macular degeneration. Investigative Ophthalmology & Visual Science. PMID 25015356 DOI: 10.1167/Iovs.14-14494  0.358
2014 Crawford DC, Crosslin DR, Tromp G, Kullo IJ, Kuivaniemi H, Hayes MG, Denny JC, Bush WS, Haines JL, Roden DM, McCarty CA, Jarvik GP, Ritchie MD. eMERGEing progress in genomics-the first seven years. Frontiers in Genetics. 5: 184. PMID 24987407 DOI: 10.3389/Fgene.2014.00184  0.641
2014 Rasmussen-Torvik LJ, Stallings SC, Gordon AS, Almoguera B, Basford MA, Bielinski SJ, Brautbar A, Brilliant MH, Carrell DS, Connolly JJ, Crosslin DR, Doheny KF, Gallego CJ, Gottesman O, Kim DS, ... ... Haines JL, et al. Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems. Clinical Pharmacology and Therapeutics. 96: 482-9. PMID 24960519 DOI: 10.1038/Clpt.2014.137  0.502
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Haines JL, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661  0.363
2014 Hoffman JD, Cooke Bailey JN, D'Aoust L, Cade W, Ayala-Haedo J, Fuzzell D, Laux R, Adams LD, Reinhart-Mercer L, Caywood L, Whitehead-Gay P, Agarwal A, Wang G, Scott WK, Pericak-Vance MA, ... Haines JL, et al. Rare complement factor H variant associated with age-related macular degeneration in the Amish. Investigative Ophthalmology & Visual Science. 55: 4455-60. PMID 24906858 DOI: 10.1167/Iovs.13-13684  0.359
2014 Ratnapriya R, Zhan X, Fariss RN, Branham KE, Zipprer D, Chakarova CF, Sergeev YV, Campos MM, Othman M, Friedman JS, Maminishkis A, Waseem NH, Brooks M, Rajasimha HK, Edwards AO, ... ... Haines JL, et al. Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration. Human Molecular Genetics. 23: 5827-37. PMID 24899048 DOI: 10.1093/Hmg/Ddu276  0.468
2014 Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, ... ... Haines JL, et al. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathologica. 127: 825-43. PMID 24770881 DOI: 10.1007/S00401-014-1282-2  0.363
2014 Loomis SJ, Kang JH, Weinreb RN, Yaspan BL, Cooke Bailey JN, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, ... ... Haines JL, et al. Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss. Ophthalmology. 121: 508-16. PMID 24572674 DOI: 10.1016/J.Ophtha.2013.09.012  0.317
2014 Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, ... ... Haines JL, et al. Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene. Translational Psychiatry. 4: e358. PMID 24495969 DOI: 10.1038/Tp.2014.2  0.392
2014 Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, ... ... Haines JL, et al. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiology of Aging. 35: 1510.e19-26. PMID 24439484 DOI: 10.1016/J.Neurobiolaging.2013.12.010  0.355
2014 Cukier HN, Dueker ND, Slifer SH, Lee JM, Whitehead PL, Lalanne E, Leyva N, Konidari I, Gentry RC, Hulme WF, Booven DV, Mayo V, Hofmann NK, Schmidt MA, Martin ER, ... Haines JL, et al. Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders. Molecular Autism. 5: 1. PMID 24410847 DOI: 10.1186/2040-2392-5-1  0.331
2014 Veatch OJ, Veenstra-Vanderweele J, Potter M, Pericak-Vance MA, Haines JL. Genetically meaningful phenotypic subgroups in autism spectrum disorders. Genes, Brain, and Behavior. 13: 276-85. PMID 24373520 DOI: 10.1111/Gbb.12117  0.418
2014 Ozel AB, Moroi SE, Reed DM, Nika M, Schmidt CM, Akbari S, Scott K, Rozsa F, Pawar H, Musch DC, Lichter PR, Gaasterland D, Branham K, Gilbert J, Garnai SJ, ... ... Haines J, et al. Genome-wide association study and meta-analysis of intraocular pressure. Human Genetics. 133: 41-57. PMID 24002674 DOI: 10.1007/S00439-013-1349-5  0.378
2014 Bush WS, Haines JL. Genotype correlation analysis reveals pathway-based functional disequilibrium and potential epistasis in the human interactome Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8602: 890-901. DOI: 10.1007/978-3-662-45523-4_72  0.519
2013 Murdock DG, Bradford Y, Schnetz-Boutaud N, Mayo P, Allen MJ, D'Aoust LN, Liang X, Mitchell SL, Zuchner S, Small GW, Gilbert JR, Pericak-Vance MA, Haines JL. KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers. Plos One. 8: e82194. PMID 24349219 DOI: 10.1371/Journal.Pone.0082194  0.528
2013 Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Basford MA, Carrell DS, Peissig PL, Kho AN, Pacheco JA, ... ... Haines JL, et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nature Biotechnology. 31: 1102-10. PMID 24270849 DOI: 10.1038/Nbt.2749  0.579
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Haines JL, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802  0.36
2013 Davis MF, Sriram S, Bush WS, Denny JC, Haines JL. Automated extraction of clinical traits of multiple sclerosis in electronic medical records. Journal of the American Medical Informatics Association : Jamia. 20: e334-40. PMID 24148554 DOI: 10.1136/Amiajnl-2013-001999  0.565
2013 Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, ... ... Haines JL, et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics. 45: 1353-60. PMID 24076602 DOI: 10.1038/Ng.2770  0.477
2013 Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, ... ... Haines JL, et al. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nature Genetics. 45: 1375-9. PMID 24036949 DOI: 10.1038/Ng.2758  0.418
2013 Cooke Bailey JN, Sobrin L, Pericak-Vance MA, Haines JL, Hammond CJ, Wiggs JL. Advances in the genomics of common eye diseases. Human Molecular Genetics. 22: R59-65. PMID 23962718 DOI: 10.1093/Hmg/Ddt396  0.444
2013 Pasquale LR, Loomis SJ, Weinreb RN, Kang JH, Yaspan BL, Bailey JC, Gaasterland D, Gaasterland T, Lee RK, Scott WK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, ... ... Haines JL, et al. Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States. Molecular Vision. 19: 1471-81. PMID 23869166  0.308
2013 Davis MF, Cummings AC, D'Aoust LN, Jiang L, Velez Edwards DR, Laux R, Reinhart-Mercer L, Fuzzell D, Scott WK, Pericak-Vance MA, Lee SL, Haines JL. Parkinson disease loci in the mid-western Amish. Human Genetics. 132: 1213-21. PMID 23793441 DOI: 10.1007/S00439-013-1316-1  0.64
2013 McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA, Rottscheit C, Peissig P, Stefanski E, McCarty CA, Zuvich RL, ... ... Haines JL, et al. Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records. Plos One. 8: e63481. PMID 23762230 DOI: 10.1371/Journal.Pone.0063481  0.768
2013 Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, ... ... Haines JL, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 761-71. PMID 23743551 DOI: 10.1038/Gim.2013.72  0.461
2013 Cummings AC, Torstenson E, Davis MF, D'Aoust LN, Scott WK, Pericak-Vance MA, Bush WS, Haines JL. Evaluating power and type 1 error in large pedigree analyses of binary traits. Plos One. 8: e62615. PMID 23658753 DOI: 10.1371/Journal.Pone.0062615  0.701
2013 Wang G, Dubovy SR, Kovach JL, Schwartz SG, Agarwal A, Scott WK, Haines JL, Pericak-Vance MA. Variants at chromosome 10q26 locus and the expression of HTRA1 in the retina. Experimental Eye Research. 112: 102-5. PMID 23644223 DOI: 10.1016/J.Exer.2013.04.019  0.444
2013 Wiggs JL, Howell GR, Linkroum K, Abdrabou W, Hodges E, Braine CE, Pasquale LR, Hannon GJ, Haines JL, John SW. Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma. Clinical Genetics. 84: 167-74. PMID 23621901 DOI: 10.1111/Cge.12176  0.309
2013 Predazzi IM, Rokas A, Deinard A, Schnetz-Boutaud N, Williams ND, Bush WS, Tacconelli A, Friedrich K, Fazio S, Novelli G, Haines JL, Sirugo G, Williams SM. Putting pleiotropy and selection into context defines a new paradigm for interpreting genetic data. Circulation. Cardiovascular Genetics. 6: 299-307. PMID 23616601 DOI: 10.1161/Circgenetics.113.000126  0.573
2013 Naj AC, Scott WK, Courtenay MD, Cade WH, Schwartz SG, Kovach JL, Agarwal A, Wang G, Haines JL, Pericak-Vance MA. Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis. Annals of Human Genetics. 77: 215-31. PMID 23577725 DOI: 10.1111/Ahg.12011  0.448
2013 Wang G, Scott WK, Agarwal A, Haines JL, Pericak-Vance MA. Coding variants in ARMS2 and the risk of age-related macular degeneration. Jama Ophthalmology. 131: 804-5. PMID 23572227 DOI: 10.1001/Jamaophthalmol.2013.589  0.44
2013 Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, ... ... Haines JL, et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. Jama. 309: 1483-92. PMID 23571587 DOI: 10.1001/Jama.2013.2973  0.432
2013 Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, ... ... Haines JL, et al. SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. Plos One. 8: e58618. PMID 23565137 DOI: 10.1371/Journal.Pone.0058618  0.369
2013 Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, ... ... Haines JL, et al. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation. 127: 1377-85. PMID 23463857 DOI: 10.1161/Circulationaha.112.000604  0.759
2013 Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, ... ... Haines JL, et al. Seven new loci associated with age-related macular degeneration. Nature Genetics. 45: 433-9, 439e1-2. PMID 23455636 DOI: 10.1038/Ng.2578  0.493
2013 Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, et al. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Annals of Human Genetics. 77: 85-105. PMID 23360175 DOI: 10.1111/Ahg.12000  0.333
2013 Kohli MA, John-Williams K, Rajbhandary R, Naj A, Whitehead P, Hamilton K, Carney RM, Wright C, Crocco E, Gwirtzman HE, Lang R, Beecham G, Martin ER, Gilbert J, Benatar M, ... ... Haines JL, et al. Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians. Neurobiology of Aging. 34: 1519.e5-12. PMID 23107433 DOI: 10.1016/J.Neurobiolaging.2012.10.003  0.371
2013 Ahmeti KB, Ajroud-Driss S, Al-Chalabi A, Andersen PM, Armstrong J, Birve A, Blauw HM, Brown RH, Bruijn L, Chen W, Chio A, Comeau MC, Cronin S, Diekstra FP, Soraya Gkazi A, ... ... Haines JL, et al. Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Neurobiology of Aging. 34: 357.e7-19. PMID 22959728 DOI: 10.1016/j.neurobiolaging.2012.07.017  0.324
2013 Wiggs JL, Hauser MA, Abdrabou W, Allingham RR, Budenz DL, Delbono E, Friedman DS, Kang JH, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Loomis S, Liu Y, McCarty C, ... ... Haines JL, et al. The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: rationale, study design, and clinical variables. Journal of Glaucoma. 22: 517-25. PMID 22828004 DOI: 10.1097/Ijg.0B013E31824D4Fd8  0.308
2013 Edwards DR, Gilbert JR, Hicks JE, Myers JL, Jiang L, Cummings AC, Guo S, Gallins PJ, Konidari I, Caywood L, Reinhart-Mercer L, Fuzzell D, Knebusch C, Laux R, Jackson CE, ... ... Haines JL, et al. Linkage and association of successful aging to the 6q25 region in large Amish kindreds. Age (Dordrecht, Netherlands). 35: 1467-77. PMID 22773346 DOI: 10.1007/S11357-012-9447-1  0.685
2013 D'Aoust L, Cummings A, Jiang L, Laux R, Fuzzell D, Caywood L, Reinhart-Mercer L, Scott W, Pericak-Vance M, Haines J. P1-064: Identification of variants that confer susceptibility to Alzheimer's disease in the Amish through exome sequencing Alzheimer's & Dementia. 9: P175-P175. DOI: 10.1016/J.Jalz.2013.05.285  0.597
2013 Pericak-Vance M, Kunkle B, Kholi M, Naj A, Perry W, Hamilton K, Whitehead PL, Levin B, Carney R, Crocco E, Wright C, Beecham G, Martin E, Wang L, Gilbert J, ... Haines J, et al. P3-021: Variant-domain mapping in confirmed late-onset Alzheimer disease (LOAD) loci identifies multiple genomic regions with potentially functional variants Alzheimer's & Dementia. 9: P557-P557. DOI: 10.1016/J.Jalz.2013.05.1090  0.316
2012 Schnetz-Boutaud NC, Hoffman J, Coe JE, Murdock DG, Pericak-Vance MA, Haines JL. Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene. Annals of Human Genetics. 76: 448-53. PMID 22943764 DOI: 10.1111/J.1469-1809.2012.00727.X  0.355
2012 Cummings AC, Jiang L, Velez Edwards DR, McCauley JL, Laux R, McFarland LL, Fuzzell D, Knebusch C, Caywood L, Reinhart-Mercer L, Nations L, Gilbert JR, Konidari I, Tramontana M, Cuccaro ML, ... ... Haines JL, et al. Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene. Annals of Human Genetics. 76: 342-51. PMID 22881374 DOI: 10.1111/J.1469-1809.2012.00721.X  0.711
2012 Jun G, Vardarajan BN, Buros J, Yu CE, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL, Lunetta KL, Pericak-Vance MA, Schellenberg GD, Farrer LA. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Archives of Neurology. 69: 1270-9. PMID 22869155 DOI: 10.1001/Archneurol.2012.2052  0.366
2012 Anney R, Klei L, Pinto D, Almeida J, Bacchelli E, Baird G, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Casey J, Conroy J, Correia C, ... ... Haines JL, et al. Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Human Molecular Genetics. 21: 4781-92. PMID 22843504 DOI: 10.1093/Hmg/Dds301  0.361
2012 Kamboh MI, Demirci FY, Wang X, Minster RL, Carrasquillo MM, Pankratz VS, Younkin SG, Saykin AJ, Jun G, Baldwin C, Logue MW, Buros J, Farrer L, Pericak-Vance MA, ... Haines JL, et al. Genome-wide association study of Alzheimer's disease. Translational Psychiatry. 2: e117. PMID 22832961 DOI: 10.1038/Tp.2012.45  0.411
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Haines JL, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.316
2012 Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Haines JL, et al. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. Plos Genetics. 8: e1002707. PMID 22685416 DOI: 10.1371/Journal.Pgen.1002707  0.329
2012 Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Hawthorne F, Budenz DL, Friedman DS, Gaasterland D, Haines J, Kang JH, Lee R, Lichter P, Liu Y, et al. Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. Investigative Ophthalmology & Visual Science. 53: 4468-74. PMID 22661486 DOI: 10.1167/Iovs.12-9784  0.346
2012 Wiggs JL, Yaspan BL, Hauser MA, Kang JH, Allingham RR, Olson LM, Abdrabou W, Fan BJ, Wang DY, Brodeur W, Budenz DL, Caprioli J, Crenshaw A, Crooks K, Delbono E, ... ... Haines JL, et al. Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. Plos Genetics. 8: e1002654. PMID 22570617 DOI: 10.1371/Journal.Pgen.1002654  0.401
2012 Griswold AJ, Ma D, Cukier HN, Nations LD, Schmidt MA, Chung RH, Jaworski JM, Salyakina D, Konidari I, Whitehead PL, Wright HH, Abramson RK, Williams SM, Menon R, Martin ER, ... Haines JL, et al. Evaluation of copy number variations reveals novel candidate genes in autism spectrum disorder-associated pathways. Human Molecular Genetics. 21: 3513-23. PMID 22543975 DOI: 10.1093/Hmg/Dds164  0.326
2012 Schwartz SG, Agarwal A, Kovach JL, Gallins PJ, Cade W, Postel EA, Wang G, Ayala-Haedo J, Spencer KM, Haines JL, Pericak-Vance MA, Scott WK. The ARMS2 A69S variant and bilateral advanced age-related macular degeneration. Retina (Philadelphia, Pa.). 32: 1486-91. PMID 22481475 DOI: 10.1097/Iae.0B013E318240A540  0.338
2012 Wang L, Hara K, Van Baaren JM, Price JC, Beecham GW, Gallins PJ, Whitehead PL, Wang G, Lu C, Slifer MA, Züchner S, Martin ER, Mash D, Haines JL, Pericak-Vance MA, et al. Vitamin D receptor and Alzheimer's disease: a genetic and functional study. Neurobiology of Aging. 33: 1844.e1-9. PMID 22306846 DOI: 10.1016/J.Neurobiolaging.2011.12.038  0.399
2012 Spencer KL, Glenn K, Brown-Gentry K, Haines JL, Crawford DC. Population differences in genetic risk for age-related macular degeneration and implications for genetic testing. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 116-7. PMID 22232482 DOI: 10.1001/Archopthalmol.2011.1370  0.688
2012 Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC, Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, ... ... Haines JL, et al. A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Human Genetics. 131: 565-79. PMID 21996756 DOI: 10.1007/S00439-011-1094-6  0.341
2012 Courtenay MD, Gilbert JR, Jiang L, Cummings AC, Gallins PJ, Caywood L, Reinhart-Mercer L, Fuzzell D, Knebusch C, Laux R, McCauley JL, Jackson CE, Pericak-Vance MA, Haines JL, Scott WK. Mitochondrial haplogroup X is associated with successful aging in the Amish. Human Genetics. 131: 201-8. PMID 21750925 DOI: 10.1007/S00439-011-1060-3  0.625
2012 Haines J, Naj A, Kohli M, Hamilton-Nelson K, Rajbhandary R, Whitehead PL, Carney R, Crocco E, Wright C, Beecham G, Martin E, Gilbert J, Zuchner S, Pericak-Vance M, Levin B. O5-03-01: Deep resequencing of 9 confirmed late-onset Alzheimer's disease (LOAD) loci identifies multiple genomic regions with potentially functional variants Alzheimer's & Dementia. 8: P734-P735. DOI: 10.1016/J.Jalz.2012.05.1981  0.402
2012 Zuchner S, Kohli M, Naj A, Hamilton K, Rajbhandary R, Plitnik T, John-Williams K, Whitehead PL, Gilbert J, Martin E, Beecham G, Haines J, Pericak-Vance M. Exome sequencing of extended late-onset Alzheimer's disease families identifies a variant in the TTC3 gene Alzheimers & Dementia. 8: 679. DOI: 10.1016/J.Jalz.2012.05.1839  0.399
2011 Patsopoulos NA, Esposito F, Reischl J, Lehr S, Bauer D, Heubach J, Sandbrink R, Pohl C, Edan G, Kappos L, ... ... Haines J, et al. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Annals of Neurology. 70: 897-912. PMID 22190364 DOI: 10.1002/Ana.22609  0.399
2011 Zuvich RL, Armstrong LL, Bielinski SJ, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes MG, Jarvik GP, Jiang L, Kullo IJ, Li R, et al. Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality. Genetic Epidemiology. 35: 887-98. PMID 22125226 DOI: 10.1002/Gepi.20639  0.798
2011 Chung RH, Ma D, Wang K, Hedges DJ, Jaworski JM, Gilbert JR, Cuccaro ML, Wright HH, Abramson RK, Konidari I, Whitehead PL, Schellenberg GD, Hakonarson H, Haines JL, Pericak-Vance MA, et al. An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males. Molecular Autism. 2: 18. PMID 22050706 DOI: 10.1186/2040-2392-2-18  0.444
2011 Salyakina D, Cukier HN, Lee JM, Sacharow S, Nations LD, Ma D, Jaworski JM, Konidari I, Whitehead PL, Wright HH, Abramson RK, Williams SM, Menon R, Haines JL, Gilbert JR, et al. Copy number variants in extended autism spectrum disorder families reveal candidates potentially involved in autism risk. Plos One. 6: e26049. PMID 22016809 DOI: 10.1371/Journal.Pone.0026049  0.343
2011 Wiggs JL, Kang JH, Yaspan BL, Mirel DB, Laurie C, Crenshaw A, Brodeur W, Gogarten S, Olson LM, Abdrabou W, DelBono E, Loomis S, Haines JL, Pasquale LR. Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Human Molecular Genetics. 20: 4707-13. PMID 21873608 DOI: 10.1093/Hmg/Ddr382  0.383
2011 Matise TC, Ambite JL, Buyske S, Carlson CS, Cole SA, Crawford DC, Haiman CA, Heiss G, Kooperberg C, Marchand LL, Manolio TA, North KE, Peters U, Ritchie MD, Hindorff LA, ... Haines JL, et al. The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. American Journal of Epidemiology. 174: 849-59. PMID 21836165 DOI: 10.1093/Aje/Kwr160  0.577
2011 Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, ... ... Haines JL, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 476: 214-9. PMID 21833088 DOI: 10.1038/Nature10251  0.804
2011 Owens SE, Summar ML, Ryckman KK, Haines JL, Reiss S, Summar SR, Aschner M. Lack of association between autism and four heavy metal regulatory genes. Neurotoxicology. 32: 769-75. PMID 21798283 DOI: 10.1016/J.Neuro.2011.07.003  0.326
2011 Edwards DR, Gilbert JR, Jiang L, Gallins PJ, Caywood L, Creason M, Fuzzell D, Knebusch C, Jackson CE, Pericak-Vance MA, Haines JL, Scott WK. Successful aging shows linkage to chromosomes 6, 7, and 14 in the Amish. Annals of Human Genetics. 75: 516-28. PMID 21668908 DOI: 10.1111/J.1469-1809.2011.00658.X  0.334
2011 Zuvich RL, Bush WS, McCauley JL, Beecham AH, De Jager PL, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Sawcer SJ, Pericak-Vance MA, Barcellos LF, Mortlock DP, Haines JL. Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex. Human Molecular Genetics. 20: 3517-24. PMID 21653641 DOI: 10.1093/Hmg/Ddr250  0.828
2011 Cummings AC, Lee SL, McCauley JL, Jiang L, Crunk A, McFarland LL, Gallins PJ, Fuzzell D, Knebusch C, Jackson CE, Scott WK, Pericak-Vance MA, Haines JL. A genome-wide linkage screen in the Amish with Parkinson disease points to chromosome 6. Annals of Human Genetics. 75: 351-8. PMID 21488853 DOI: 10.1111/J.1469-1809.2011.00643.X  0.704
2011 Spencer KL, Olson LM, Schnetz-Boutaud N, Gallins P, Agarwal A, Iannaccone A, Kritchevsky SB, Garcia M, Nalls MA, Newman AB, Scott WK, Pericak-Vance MA, Haines JL. Using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration. Plos One. 6: e17784. PMID 21455292 DOI: 10.1371/Journal.Pone.0017784  0.685
2011 Fan BJ, Wang DY, Pasquale LR, Haines JL, Wiggs JL. Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population. Investigative Ophthalmology & Visual Science. 52: 1788-92. PMID 21398277 DOI: 10.1167/iovs.10-6339  0.327
2011 Kuchtey J, Olson LM, Rinkoski T, Mackay EO, Iverson TM, Gelatt KN, Haines JL, Kuchtey RW. Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma. Plos Genetics. 7: e1001306. PMID 21379321 DOI: 10.1371/Journal.Pgen.1001306  0.327
2011 Bush WS, McCauley JL, DeJager PL, Dudek SM, Hafler DA, Gibson RA, Matthews PM, Kappos L, Naegelin Y, Polman CH, Hauser SL, Oksenberg J, Haines JL, Ritchie MD. A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes and Immunity. 12: 335-40. PMID 21346779 DOI: 10.1038/Gene.2011.3  0.676
2011 Yaspan BL, Bush WS, Torstenson ES, Ma D, Pericak-Vance MA, Ritchie MD, Sutcliffe JS, Haines JL. Genetic analysis of biological pathway data through genomic randomization. Human Genetics. 129: 563-71. PMID 21279722 DOI: 10.1007/S00439-011-0956-2  0.731
2011 Turner S, Armstrong LL, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes G, Jarvik G, Jiang L, Kullo IJ, Li R, Ling H, et al. Quality control procedures for genome-wide association studies. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit1.19. PMID 21234875 DOI: 10.1002/0471142905.Hg0119S68  0.788
2011 Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, ... ... Haines JL, et al. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Archives of Neurology. 68: 99-106. PMID 21220680 DOI: 10.1001/Archneurol.2010.346  0.327
2011 Spencer KL, Olson LM, Schnetz-Boutaud N, Gallins P, Wang G, Scott WK, Agarwal A, Jakobsdottir J, Conley Y, Weeks DE, Gorin MB, Pericak-Vance MA, Haines JL. Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration susceptibility. Investigative Ophthalmology & Visual Science. 52: 1748-54. PMID 21169531 DOI: 10.1167/Iovs.09-5112  0.717
2011 Naj A, Jun G, Buros J, Gallins P, Farrer L, Haines J, Pericak-Vance M, Schellenberg G. Genome-Wide Association Study of Late-Onset Alzheimer Disease Identifies Disease-Associated Variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1 Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.530  0.395
2011 Martin E, Naj A, Park YS, Gallins P, Hamilton K, Rajbhandary R, Haines J, Pericak-Vance M. Genome-Wide Association Analysis Identifies Novel Loci Associated with the Onset Age Among Cases with Late-Onset Alzheimer’s Disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.526  0.445
2011 Cummings A, Haines J, Pericak-Vance M, Laux R, Jiang L, Edwards DV, McFarland L, Caywood L, Reinhart-Mercer L, Fuzzell D, Knebusch C, Jackson C, McCauley J, Scott W. O1-01-01: Genome-wide study for Alzheimer's disease in the Amish Alzheimer's & Dementia. 7: S92-S92. DOI: 10.1016/J.Jalz.2011.05.225  0.574
2010 Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, Pulley JM, Basford MA, Masys DR, Haines JL, Roden DM. Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. Circulation. 122: 2016-21. PMID 21041692 DOI: 10.1161/Circulationaha.110.948828  0.464
2010 Naj AC, Beecham GW, Martin ER, Gallins PJ, Powell EH, Konidari I, Whitehead PL, Cai G, Haroutunian V, Scott WK, Vance JM, Slifer MA, Gwirtsman HE, Gilbert JR, Haines JL, et al. Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. Plos Genetics. 6: e1001130. PMID 20885792 DOI: 10.1371/Journal.Pgen.1001130  0.361
2010 Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, ... Haines JL, et al. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. Journal of Alzheimer's Disease : Jad. 22: 247-55. PMID 20847397 DOI: 10.3233/Jad-2010-100933  0.342
2010 Dumitrescu L, Ritchie MD, Brown-Gentry K, Pulley JM, Basford M, Denny JC, Oksenberg JR, Roden DM, Haines JL, Crawford DC. Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 12: 648-50. PMID 20733501 DOI: 10.1097/Gim.0B013E3181Efe2Df  0.443
2010 Briggs FB, Bartlett SE, Goldstein BA, Wang J, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, ... Haines JL, et al. Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. Human Molecular Genetics. 19: 4286-95. PMID 20699326 DOI: 10.1093/Hmg/Ddq328  0.788
2010 Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, ... ... Haines JL, et al. A genome-wide scan for common alleles affecting risk for autism. Human Molecular Genetics. 19: 4072-82. PMID 20663923 DOI: 10.1093/Hmg/Ddq307  0.381
2010 Cree BA, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, et al. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. Plos One. 5: e11296. PMID 20593013 DOI: 10.1371/Journal.Pone.0011296  0.424
2010 Ban M, McCauley JL, Zuvich R, Baker A, Bergamaschi L, Cox M, Kemppinen A, D'Alfonso S, Guerini FR, Lechner-Scott J, Dudbridge F, Wason J, Robertson NP, De Jager PL, Hafler DA, ... ... Haines J, et al. A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes and Immunity. 11: 660-4. PMID 20574445 DOI: 10.1038/Gene.2010.36  0.785
2010 Beecham GW, Martin ER, Gilbert JR, Haines JL, Pericak-Vance MA. APOE is not associated with Alzheimer disease: a cautionary tale of genotype imputation. Annals of Human Genetics. 74: 189-94. PMID 20529013 DOI: 10.1111/J.1469-1809.2010.00573.X  0.357
2010 Beecham GW, Naj AC, Gilbert JR, Haines JL, Buxbaum JD, Pericak-Vance MA. PCDH11X variation is not associated with late-onset Alzheimer disease susceptibility. Psychiatric Genetics. 20: 321-4. PMID 20523261 DOI: 10.1097/Ypg.0B013E32833B635D  0.318
2010 Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, et al. Variation within DNA repair pathway genes and risk of multiple sclerosis. American Journal of Epidemiology. 172: 217-24. PMID 20522537 DOI: 10.1093/Aje/Kwq086  0.785
2010 Booth DR, Heard RN, Stewart GJ, Cox M, Scott RJ, Lechner-Scott J, Goris A, Dobosi R, Dubois B, Saarela J, Leppä V, Peltonen L, Pirttila T, Cournu-Rebeix I, ... ... Haines J, et al. Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. Nature Genetics. 42: 469-70; author reply. PMID 20502484 DOI: 10.1038/Ng0610-469  0.366
2010 Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, ... ... Haines JL, et al. Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 107: 7401-6. PMID 20385819 DOI: 10.1073/Pnas.0912702107  0.444
2010 Ayala-Haedo JA, Gallins PJ, Whitehead PL, Schwartz SG, Kovach JL, Postel EA, Agarwal A, Wang G, Haines JL, Pericak-Vance MA, Scott WK. Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration. Annals of Human Genetics. 74: 195-201. PMID 20374233 DOI: 10.1111/J.1469-1809.2010.00570.X  0.393
2010 Bush WS, Sawcer SJ, de Jager PL, Oksenberg JR, McCauley JL, Pericak-Vance MA, Haines JL. Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come. American Journal of Human Genetics. 86: 621-5. PMID 20362272 DOI: 10.1016/J.Ajhg.2010.02.027  0.634
2010 Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K, Balser JR, Masys DR, Haines JL, Roden DM. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. American Journal of Human Genetics. 86: 560-72. PMID 20362271 DOI: 10.1016/J.Ajhg.2010.03.003  0.536
2010 Bronson PG, Caillier S, Ramsay PP, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Sawcer SJ, Pericak-Vance MA, Haines JL, Hauser SL, et al. CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis. Human Molecular Genetics. 19: 2331-40. PMID 20211854 DOI: 10.1093/Hmg/Ddq101  0.779
2010 Wang G, Spencer KL, Scott WK, Whitehead P, Court BL, Ayala-Haedo J, Mayo P, Schwartz SG, Kovach JL, Gallins P, Polk M, Agarwal A, Postel EA, Haines JL, Pericak-Vance MA. Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. Human Genetics. 127: 595-602. PMID 20182747 DOI: 10.1007/S00439-010-0805-8  0.689
2010 Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL, Aubin C, Cross AH, Piccio L, Aggarwal NT, Evans D, Hafler DA, Compston A, Hauser SL, Pericak-Vance MA, ... Haines JL, et al. Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Human Genetics. 127: 525-35. PMID 20112030 DOI: 10.1007/S00439-010-0789-4  0.81
2010 Edwards TL, Scott WK, Almonte C, Burt A, Powell EH, Beecham GW, Wang L, Züchner S, Konidari I, Wang G, Singer C, Nahab F, Scott B, Stajich JM, Pericak-Vance M, ... Haines J, et al. Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Annals of Human Genetics. 74: 97-109. PMID 20070850 DOI: 10.1111/J.1469-1809.2009.00560.X  0.347
2010 Bush WS, Haines J. Overview of linkage analysis in complex traits. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 1.9.1-18. PMID 20063263 DOI: 10.1002/0471142905.Hg0109S64  0.646
2010 Edwards DR, Gallins P, Polk M, Ayala-Haedo J, Schwartz SG, Kovach JL, Spencer K, Wang G, Agarwal A, Postel EA, Haines JL, Pericak-Vance M, Scott WK. Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms. Investigative Ophthalmology & Visual Science. 51: 1873-9. PMID 19933179 DOI: 10.1167/Iovs.09-4000  0.681
2010 Reitz C, Tokuhiro S, Clark L, Conrad C, Vonsattel J, Lantigua R, Medrano M, Simkin I, Haines J, Pericak-Vance M, Farrer L, Lee J, Rogaeva E, George-Hyslop PS, Mayeux R. Sorcs1 Alters APP Processing and Variants may Increase Alzheimer's Disease Risk Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.091  0.337
2010 Cummings A, Jiang L, Edwards DV, Laux R, McFarland L, Gallins P, Caywood L, Creason M, Fuzzell D, Knebusch C, Tramontana M, Slifer M, Jackson C, Scott W, Pericak-Vance M, ... ... Haines J, et al. P1-100: Genome-wide association study for late-onset Alzheimer's disease in the Mid-Western U.S. Amish Alzheimer's & Dementia. 6: S203-S203. DOI: 10.1016/J.Jalz.2010.05.648  0.634
2010 Cummings AC, Jiang L, Edwards DV, Laux R, McFarland LL, Gallins PJ, Caywood L, Creason M, Fuzzell D, Knebusch C, Tramontana MG, Slifer MA, Jackson CE, Scott WK, Pericak-Vance MA, ... ... Haines JL, et al. Genome-wide linkage study in the Amish shows evidence for a chromosome 3 locus in late-onset Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.220  0.666
2010 Le TM, Willis AS, Haines JL, Summar ML, Cornfield DN. An Insertion/Deletion Polymorphism in the Glutathione Biosynthesis Pathway Is Associated with Earlier Onset of Alzheimer's Disease and Increased Susceptibility to Oxidant Injury In Vitro Free Radical Biology and Medicine. 49: S188. DOI: 10.1016/J.Freeradbiomed.2010.10.538  0.359
2009 Pericak-Vance MA, Haines JL. Beyond proof of principle: new genes for Alzheimer's disease through collaboration. The Lancet. Neurology. 8: 977-9. PMID 19833292 DOI: 10.1016/S1474-4422(09)70277-7  0.398
2009 Weiss LA, Arking DE, Daly MJ, Chakravarti A, Brune CW, West K, O'Connor A, Hilton G, Tomlinson RL, West AB, Cook EH, Green T, Chang SC, Gabriel S, Gates C, ... ... Haines JL, et al. A genome-wide linkage and association scan reveals novel loci for autism Nature. 461: 802-808. PMID 19812673 DOI: 10.1038/Nature08490  0.437
2009 Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, ... ... Haines JL, et al. Finding the missing heritability of complex diseases. Nature. 461: 747-53. PMID 19812666 DOI: 10.1038/Nature08494  0.358
2009 Zuvich RL, McCauley JL, Pericak-Vance MA, Haines JL. Genetics and pathogenesis of multiple sclerosis. Seminars in Immunology. 21: 328-33. PMID 19775910 DOI: 10.1016/J.Smim.2009.08.003  0.784
2009 Schnetz-Boutaud NC, Anderson BM, Brown KD, Wright HH, Abramson RK, Cuccaro ML, Gilbert JR, Pericak-Vance MA, Haines JL. Examination of tetrahydrobiopterin pathway genes in autism. Genes, Brain, and Behavior. 8: 753-7. PMID 19674121 DOI: 10.1111/J.1601-183X.2009.00521.X  0.449
2009 McCauley JL, Zuvich RL, Bradford Y, Kenealy SJ, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Mortlock DP, Pericak-Vance MA, Haines JL. Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes and Immunity. 10: 624-30. PMID 19626040 DOI: 10.1038/Gene.2009.53  0.824
2009 De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S, Baranzini SE, McCauley JL, ... ... Haines JL, et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nature Genetics. 41: 776-82. PMID 19525953 DOI: 10.1038/Ng.401  0.305
2009 Ma D, Salyakina D, Jaworski JM, Konidari I, Whitehead PL, Andersen AN, Hoffman JD, Slifer SH, Hedges DJ, Cukier HN, Griswold AJ, McCauley JL, Beecham GW, Wright HH, Abramson RK, ... ... Haines JL, et al. A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. Annals of Human Genetics. 73: 263-73. PMID 19456320 DOI: 10.1111/J.1469-1809.2009.00523.X  0.499
2009 Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS, Salyakina D, Imielinski M, Bradfield JP, Sleiman PM, Kim CE, Hou C, Frackelton E, Chiavacci R, Takahashi N, ... ... Haines JL, et al. Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature. 459: 528-33. PMID 19404256 DOI: 10.1038/Nature07999  0.302
2009 Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, ... ... Haines J, et al. Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. European Journal of Human Genetics : Ejhg. 17: 1309-13. PMID 19293837 DOI: 10.1038/Ejhg.2009.41  0.465
2009 Wang G, Spencer KL, Court BL, Olson LM, Scott WK, Haines JL, Pericak-Vance MA. Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria. Investigative Ophthalmology & Visual Science. 50: 3084-90. PMID 19255159 DOI: 10.1167/Iovs.08-3240  0.649
2009 Liang X, Slifer M, Martin ER, Schnetz-Boutaud N, Bartlett J, Anderson B, Züchner S, Gwirtsman H, Gilbert JR, Pericak-Vance MA, Haines JL. Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10. Human Mutation. 30: 463-71. PMID 19241460 DOI: 10.1002/Humu.20953  0.6
2009 Srinivasan BS, Chen J, Cheng C, Conti D, Duan S, Fridley BL, Gu X, Haines JL, Jorgenson E, Kraja A, Lasky-Su J, Li L, Rodin A, Wang D, Province M, et al. Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group. Pharmacogenomics. 10: 243-51. PMID 19207025 DOI: 10.2217/14622416.10.2.243  0.515
2009 Anderson BM, Schnetz-Boutaud NC, Bartlett J, Wotawa AM, Wright HH, Abramson RK, Cuccaro ML, Gilbert JR, Pericak-Vance MA, Haines JL. Examination of association of genes in the serotonin system to autism. Neurogenetics. 10: 209-16. PMID 19184136 DOI: 10.1007/S10048-009-0171-7  0.472
2009 Beecham GW, Martin ER, Li YJ, Slifer MA, Gilbert JR, Haines JL, Pericak-Vance MA. Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. American Journal of Human Genetics. 84: 35-43. PMID 19118814 DOI: 10.1016/J.Ajhg.2008.12.008  0.501
2009 Edwards TL, Pericak-Vance M, Gilbert JR, Haines JL, Martin ER, Ritchie MD. An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 721-35. PMID 19105203 DOI: 10.1002/Ajmg.B.30899  0.555
2009 Edwards T, Scott W, Almonte C, Burt A, Powell E, Beecham G, Wang L, Zuchner S, Konidari I, Wang G, Pericak-Vance M, Haines J, Vance J, Martin E. P3.116 Genome-wide signiflcant conflrmation of SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease Parkinsonism & Related Disorders. 15: S178. DOI: 10.1016/S1353-8020(09)70680-7  0.314
2008 Anderson BM, Schnetz-Boutaud N, Bartlett J, Wright HH, Abramson RK, Cuccaro ML, Gilbert JR, Pericak-Vance MA, Haines JL. Examination of association to autism of common genetic variationin genes related to dopamine. Autism Research : Official Journal of the International Society For Autism Research. 1: 364-9. PMID 19360691 DOI: 10.1002/Aur.55  0.397
2008 Züchner S, Gilbert JR, Martin ER, Leon-Guerrero CR, Xu PT, Browning C, Bronson PG, Whitehead P, Schmechel DE, Haines JL, Pericak-Vance MA. Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3. Annals of Human Genetics. 72: 725-31. PMID 18761660 DOI: 10.1111/J.1469-1809.2008.00474.X  0.371
2008 Barcellos LF, Ramsay PP, Caillier SJ, Sawcer S, Haines J, Schmidt S, Pericak-Vance M, Compston DA, Gabatto P, Hauser SL, Oksenberg JR. Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. Genes and Immunity. 9: 493-500. PMID 18580885 DOI: 10.1038/Gene.2008.41  0.363
2008 Canter JA, Olson LM, Spencer K, Schnetz-Boutaud N, Anderson B, Hauser MA, Schmidt S, Postel EA, Agarwal A, Pericak-Vance MA, Sternberg P, Haines JL. Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration. Plos One. 3: e2091. PMID 18461138 DOI: 10.1371/Journal.Pone.0002091  0.71
2008 Spencer KL, Olson LM, Anderson BM, Schnetz-Boutaud N, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL. C3 R102G polymorphism increases risk of age-related macular degeneration. Human Molecular Genetics. 17: 1821-4. PMID 18325906 DOI: 10.1093/Hmg/Ddn075  0.716
2008 Wang L, Hauser ER, Shah SH, Seo D, Sivashanmugam P, Exum ST, Gregory SG, Granger CB, Haines JL, Jones CJ, Crossman D, Haynes C, Kraus WE, Freedman NJ, Pericak-Vance MA, et al. Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease. Annals of Human Genetics. 72: 443-53. PMID 18318786 DOI: 10.1111/J.1469-1809.2008.00433.X  0.308
2008 Spencer KL, Hauser MA, Olson LM, Schmidt S, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL. Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration. Human Molecular Genetics. 17: 971-7. PMID 18084039 DOI: 10.1093/Hmg/Ddm369  0.727
2008 Thornton-Wells TA, Moore JH, Martin ER, Pericak-Vance MA, Haines JL. Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis. Genetic Epidemiology. 32: 187-203. PMID 18076107 DOI: 10.1002/Gepi.20294  0.335
2008 Shuler RK, Schmidt S, Gallins P, Hauser MA, Scott WK, Caldwell J, Agarwal A, Haines JL, Pericak-Vance MA, Postel EA. Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration. Ophthalmology. 115: 520-4. PMID 18067970 DOI: 10.1016/J.Ophtha.2007.06.021  0.412
2008 Shuler RK, Schmidt S, Gallins P, Hauser MA, Scott WK, Caldwell J, Agarwal A, Haines JL, Pericak-Vance MA, Postel EA. Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration. American Journal of Ophthalmology. 145: 303-307. PMID 18061132 DOI: 10.1016/J.Ajo.2007.09.027  0.398
2008 Liang X, Schnetz-Boutaud N, Bartlett J, Allen MJ, Gwirtsman H, Schmechel DE, Carney RM, Gilbert JR, Pericak-Vance MA, Haines JL. No association between SNP rs498055 on chromosome 10 and late-onset Alzheimer disease in multiple datasets. Annals of Human Genetics. 72: 141-4. PMID 17725684 DOI: 10.1111/J.1469-1809.2007.00394.X  0.579
2008 Slifer MA, Beecham GW, Martin ER, Wang G, Gilbert JR, Haines JL, Vance J, Pericak-Vance MA. O2-06-02: A genetic susceptibility locus for depression of Alzheimer's disease and Parkinson's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.350  0.327
2008 Gilbert JR, Beecham G, Gallins P, Slifer M, Martin ER, Haines J, Pericak-Vance MA. P3-223: Genome-wide association analysis of the age-at-onset for individuals with Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1790  0.42
2007 Haines JL, Spencer KM, Pericak-Vance MA. Bringing the genetics of macular degeneration into focus. Proceedings of the National Academy of Sciences of the United States of America. 104: 16725-6. PMID 17940012 DOI: 10.1073/Pnas.0708151104  0.313
2007 Xu PT, Li YJ, Qin XJ, Kroner C, Green-Odlum A, Xu H, Wang TY, Schmechel DE, Hulette CM, Ervin J, Hauser M, Haines J, Pericak-Vance MA, Gilbert JR. A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. Molecular and Cellular Neurosciences. 36: 313-31. PMID 17822919 DOI: 10.1016/J.Mcn.2007.06.009  0.353
2007 Spencer KL, Hauser MA, Olson LM, Schnetz-Boutaud N, Scott WK, Schmidt S, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL. Haplotypes spanning the complement factor H gene are protective against age-related macular degeneration. Investigative Ophthalmology & Visual Science. 48: 4277-83. PMID 17724217 DOI: 10.1167/Iovs.06-1427  0.711
2007 Liang X, Trentham-Dietz A, Titus-Ernstoff L, Newcomb PA, Welch RA, Hutchinson AA, Hampton JM, Sutcliffe CB, Haines JL, Egan KM. Whole-genome amplification of oral rinse self-collected DNA in a population-based case-control study of breast cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1610-4. PMID 17684135 DOI: 10.1158/1055-9965.Epi-07-0110  0.509
2007 McCauley JL, Kenealy SJ, Margulies EH, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Pericak-Vance MA, Haines JL, Mortlock DP. SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach. Bmc Genomics. 8: 266. PMID 17683615 DOI: 10.1186/1471-2164-8-266  0.831
2007 Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, ... ... Haines JL, et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nature Genetics. 39: 1083-91. PMID 17660817 DOI: 10.1038/Ng2103  0.393
2007 Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, ... Haines JL, et al. Risk alleles for multiple sclerosis identified by a genomewide study. The New England Journal of Medicine. 357: 851-62. PMID 17660530 DOI: 10.1056/Nejmoa073493  0.36
2007 Williams SM, Canter JA, Crawford DC, Moore JH, Ritchie MD, Haines JL. Problems with genome-wide association studies. Science (New York, N.Y.). 316: 1840-2. PMID 17605173  0.461
2007 Spencer KL, Hauser MA, Olson LM, Schmidt S, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL. Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration. Human Molecular Genetics. 16: 1986-92. PMID 17576744 DOI: 10.1093/Hmg/Ddm146  0.726
2007 Liang X, Martin ER, Schnetz-Boutaud N, Bartlett J, Anderson B, Züchner S, Gwirtsman H, Schmechel D, Carney R, Gilbert JR, Pericak-Vance MA, Haines JL. Effect of heterogeneity on the chromosome 10 risk in late-onset Alzheimer disease. Human Mutation. 28: 1065-73. PMID 17573676 DOI: 10.1002/Humu.20567  0.605
2007 Wang L, Hauser ER, Shah SH, Pericak-Vance MA, Haynes C, Crosslin D, Harris M, Nelson S, Hale AB, Granger CB, Haines JL, Jones CJ, Crossman D, Seo D, Gregory SG, et al. Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease. American Journal of Human Genetics. 80: 650-63. PMID 17357071 DOI: 10.1086/512981  0.344
2007 Szatmari P, Paterson AD, Zwaigenbaum L, Roberts W, Brian J, Liu XQ, Vincent JB, Skaug JL, Thompson AP, Senman L, Feuk L, Qian C, Bryson SE, Jones MB, ... ... Haines JL, et al. Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genetics. 39: 319-28. PMID 17322880 DOI: 10.1038/Ng1985  0.342
2007 Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, ... ... Haines JL, et al. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Annals of Neurology. 61: 228-36. PMID 17252545 DOI: 10.1002/Ana.21063  0.323
2007 Scott WK, Schmidt S, Hauser MA, Gallins P, Schnetz-Boutaud N, Spencer KL, Gilbert JR, Agarwal A, Postel EA, Haines JL, Pericak-Vance MA. Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration. Ophthalmology. 114: 1151-6. PMID 17241667 DOI: 10.1016/J.Ophtha.2006.08.054  0.648
2007 Shuler RK, Hauser MA, Caldwell J, Gallins P, Schmidt S, Scott WK, Agarwal A, Haines JL, Pericak-Vance MA, Postel EA. Neovascular age-related macular degeneration and its association with LOC387715 and complement factor H polymorphism. Archives of Ophthalmology (Chicago, Ill. : 1960). 125: 63-7. PMID 17210853 DOI: 10.1001/Archopht.125.1.63  0.368
2007 Ma DQ, Cuccaro ML, Jaworski JM, Haynes CS, Stephan DA, Parod J, Abramson RK, Wright HH, Gilbert JR, Haines JL, Pericak-Vance MA. Dissecting the locus heterogeneity of autism: significant linkage to chromosome 12q14. Molecular Psychiatry. 12: 376-84. PMID 17179998 DOI: 10.1038/Sj.Mp.4001927  0.337
2007 Liang X, Schnetz-Boutaud N, Bartlett J, Anderson BM, Gwirtsman H, Schmechel D, Carney R, Gilbert JR, Pericak-Vance MA, Haines JL. Association analysis of genetic polymorphisms in the CDC2 gene with late-onset Alzheimer disease. Dementia and Geriatric Cognitive Disorders. 23: 126-32. PMID 17159347 DOI: 10.1159/000097857  0.585
2007 Motsinger AA, Brassat D, Caillier SJ, Erlich HA, Walker K, Steiner LL, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes. Neurogenetics. 8: 11-20. PMID 17024427 DOI: 10.1007/S10048-006-0058-9  0.553
2007 Hauser SL, Barcellos LF, Pericak-Vance M, Haines JL, Oksenberg JR. Clustering of autoimmune disease in families at high risk for multiple sclerosis? - Authors' reply Lancet Neurology. 6: 207. DOI: 10.1016/S1474-4422(07)70044-3  0.319
2006 Li YJ, Xu P, Qin X, Schmechel DE, Hulette CM, Haines JL, Pericak-Vance MA, Gilbert JR. A comparative analysis of the information content in long and short SAGE libraries. Bmc Bioinformatics. 7: 504. PMID 17109755 DOI: 10.1186/1471-2105-7-504  0.349
2006 Barcellos LF, Kamdar BB, Ramsay PP, DeLoa C, Lincoln RR, Caillier S, Schmidt S, Haines JL, Pericak-Vance MA, Oksenberg JR, Hauser SL. Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. The Lancet. Neurology. 5: 924-31. PMID 17052659 DOI: 10.1016/S1474-4422(06)70552-X  0.363
2006 Shah SH, Kraus WE, Crossman DC, Granger CB, Haines JL, Jones CJ, Mooser V, Huang L, Haynes C, Dowdy E, Vega GL, Grundy SM, Vance JM, Hauser ER. Serum lipids in the GENECARD study of coronary artery disease identify quantitative trait loci and phenotypic subsets on chromosomes 3q and 5q. Annals of Human Genetics. 70: 738-48. PMID 17044848 DOI: 10.1111/J.1469-1809.2006.00288.X  0.305
2006 Ritchie MD, Haas DW, Motsinger AA, Donahue JP, Erdem H, Raffanti S, Rebeiro P, George AL, Kim RB, Haines JL, Sterling TR. Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 43: 779-82. PMID 16912956 DOI: 10.1086/507101  0.446
2006 Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, et al. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Human Molecular Genetics. 15: 2813-24. PMID 16905561 DOI: 10.1093/Hmg/Ddl223  0.444
2006 Kallianpur AR, Hulgan T, Canter JA, Ritchie MD, Haines JL, Robbins GK, Shafer RW, Clifford DB, Haas DW. Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy. Aids (London, England). 20: 1503-13. PMID 16847405 DOI: 10.1097/01.Aids.0000237366.56864.3C  0.393
2006 Lin PI, Martin ER, Bronson PG, Browning-Large C, Small GW, Schmechel DE, Welsh-Bohmer KA, Haines JL, Gilbert JR, Pericak-Vance MA. Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease. Neurology. 67: 64-8. PMID 16832079 DOI: 10.1212/01.Wnl.0000223438.90113.4E  0.373
2006 Postel EA, Agarwal A, Caldwell J, Gallins P, Toth C, Schmidt S, Scott WK, Hauser MA, Haines JL, Pericak-Vance MA. Complement factor H increases risk for atrophic age-related macular degeneration. Ophthalmology. 113: 1504-7. PMID 16828512 DOI: 10.1016/J.Ophtha.2006.02.049  0.372
2006 Collins AL, Ma D, Whitehead PL, Martin ER, Wright HH, Abramson RK, Hussman JP, Haines JL, Cuccaro ML, Gilbert JR, Pericak-Vance MA. Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Neurogenetics. 7: 167-74. PMID 16770606 DOI: 10.1007/S10048-006-0045-1  0.415
2006 Lin PI, Martin ER, Browning-Large CA, Schmechel DE, Welsh-Bohmer KA, Doraiswamy PM, Gilbert JR, Haines JL, Pericak-Vance MA. Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis. Neurogenetics. 7: 157-65. PMID 16770605 DOI: 10.1007/S10048-006-0047-Z  0.371
2006 Schmidt S, Pericak-Vance MA, Sawcer S, Barcellos LF, Hart J, Sims J, Prokop AM, van der Walt J, DeLoa C, Lincoln RR, Oksenberg JR, Compston A, Hauser SL, Haines JL, Gregory SG, et al. Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis. Genes and Immunity. 7: 384-92. PMID 16738668 DOI: 10.1038/Sj.Gene.6364311  0.357
2006 Burwick RM, Ramsay PP, Haines JL, Hauser SL, Oksenberg JR, Pericak-Vance MA, Schmidt S, Compston A, Sawcer S, Cittadella R, Savettieri G, Quattrone A, Polman CH, Uitdehaag BM, Zwemmer JN, et al. APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology. 66: 1373-83. PMID 16682670 DOI: 10.1212/01.Wnl.0000210531.19498.3F  0.335
2006 Rabionet R, McCauley JL, Jaworski JM, Ashley-Koch AE, Martin ER, Sutcliffe JS, Haines JL, DeLong GR, Abramson RK, Wright HH, Cuccaro ML, Gilbert JR, Pericak-Vance MA. Lack of association between autism and SLC25A12. The American Journal of Psychiatry. 163: 929-31. PMID 16648338 DOI: 10.1176/Ajp.2006.163.5.929  0.411
2006 Schmidt S, Hauser MA, Scott WK, Postel EA, Agarwal A, Gallins P, Wong F, Chen YS, Spencer K, Schnetz-Boutaud N, Haines JL, Pericak-Vance MA. Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. American Journal of Human Genetics. 78: 852-64. PMID 16642439 DOI: 10.1086/503822  0.722
2006 Brassat D, Motsinger AA, Caillier SJ, Erlich HA, Walker K, Steiner LL, Cree BA, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans. Genes and Immunity. 7: 310-5. PMID 16625214 DOI: 10.1038/Sj.Gene.6364299  0.552
2006 Thornton-Wells TA, Moore JH, Haines JL. Dissecting trait heterogeneity: a comparison of three clustering methods applied to genotypic data. Bmc Bioinformatics. 7: 204. PMID 16611359 DOI: 10.1186/1471-2105-7-204  0.358
2006 Slifer MA, Martin ER, Bronson PG, Browning-Large C, Doraiswamy PM, Welsh-Bohmer KA, Gilbert JR, Haines JL, Pericak-Vance MA. Lack of association between UBQLN1 and Alzheimer disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 208-13. PMID 16526030 DOI: 10.1002/Ajmg.B.30298  0.314
2006 McCauley JL, Hahs DW, Jiang L, Scott WK, Welsh-Bohmer KA, Jackson CE, Vance JM, Pericak-Vance MA, Haines JL. Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish. Bmc Medical Genetics. 7: 19. PMID 16515697 DOI: 10.1186/1471-2350-7-19  0.386
2006 Hahs DW, McCauley JL, Crunk AE, McFarland LL, Gaskell PC, Jiang L, Slifer SH, Vance JM, Scott WK, Welsh-Bohmer KA, Johnson SR, Jackson CE, Pericak-Vance MA, Haines JL. A genome-wide linkage analysis of dementia in the Amish. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 160-6. PMID 16389594 DOI: 10.1002/Ajmg.B.30257  0.388
2006 Haines JL, Schnetz-Boutaud N, Schmidt S, Scott WK, Agarwal A, Postel EA, Olson L, Kenealy SJ, Hauser M, Gilbert JR, Pericak-Vance MA. Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6. Investigative Ophthalmology & Visual Science. 47: 329-35. PMID 16384981 DOI: 10.1167/Iovs.05-0116  0.822
2006 Kenealy SJ, Herrel LA, Bradford Y, Schnetz-Boutaud N, Oksenberg JR, Hauser SL, Barcellos LF, Schmidt S, Gregory SG, Pericak-Vance MA, Haines JL. Examination of seven candidate regions for multiple sclerosis: strong evidence of linkage to chromosome 1q44. Genes and Immunity. 7: 73-6. PMID 16341055 DOI: 10.1038/Sj.Gene.6364275  0.807
2006 Liang X, Schnetz-Boutaud N, Kenealy SJ, Jiang L, Bartlett J, Lynch B, Gaskell PC, Gwirtsman H, McFarland L, Bembe ML, Bronson P, Gilbert JR, Martin ER, Pericak-Vance MA, Haines JL. Covariate analysis of late-onset Alzheimer disease refines the chromosome 12 locus. Molecular Psychiatry. 11: 280-5. PMID 16222332 DOI: 10.1038/Sj.Mp.4001766  0.816
2006 Li YJ, Scott WK, Zhang L, Lin PI, Oliveira SA, Skelly T, Doraiswamy MP, Welsh-Bohmer KA, Martin ER, Haines JL, Pericak-Vance MA, Vance JM. Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases. Neurobiology of Aging. 27: 1087-93. PMID 15985314 DOI: 10.1016/J.Neurobiolaging.2005.05.013  0.398
2005 Martin ER, Bronson PG, Li YJ, Wall N, Chung RH, Schmechel DE, Small G, Xu PT, Bartlett J, Schnetz-Boutaud N, Haines JL, Gilbert JR, Pericak-Vance MA. Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. Journal of Medical Genetics. 42: 787-92. PMID 16199552 DOI: 10.1136/Jmg.2004.029553  0.397
2005 Hulgan T, Haas DW, Haines JL, Ritchie MD, Robbins GK, Shafer RW, Clifford DB, Kallianpur AR, Summar M, Canter JA. Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. Aids (London, England). 19: 1341-9. PMID 16103764 DOI: 10.1097/01.Aids.0000180786.02930.A1  0.408
2005 Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, ... ... Haines JL, et al. A high-density screen for linkage in multiple sclerosis. American Journal of Human Genetics. 77: 454-67. PMID 16080120 DOI: 10.1086/444547  0.826
2005 van der Walt JM, Scott WK, Slifer S, Gaskell PC, Martin ER, Welsh-Bohmer K, Creason M, Crunk A, Fuzzell D, McFarland L, Kroner CC, Jackson CE, Haines JL, Pericak-Vance MA. Maternal lineages and Alzheimer disease risk in the Old Order Amish. Human Genetics. 118: 115-22. PMID 16078048 DOI: 10.1007/S00439-005-0032-X  0.37
2005 Fisher SA, Abecasis GR, Yashar BM, Zareparsi S, Swaroop A, Iyengar SK, Klein BE, Klein R, Lee KE, Majewski J, Schultz DW, Klein ML, Seddon JM, Santangelo SL, Weeks DE, ... ... Haines JL, et al. Meta-analysis of genome scans of age-related macular degeneration. Human Molecular Genetics. 14: 2257-64. PMID 15987700 DOI: 10.1093/Hmg/Ddi230  0.492
2005 Allingham RR, Wiggs JL, Hauser ER, Larocque-Abramson KR, Santiago-Turla C, Broomer B, Del Bono EA, Graham FL, Haines JL, Pericak-Vance MA, Hauser MA. Early adult-onset POAG linked to 15q11-13 using ordered subset analysis. Investigative Ophthalmology & Visual Science. 46: 2002-5. PMID 15914615 DOI: 10.1167/Iovs.04-1477  0.476
2005 Postel EA, Agarwal A, Schmidt S, Fan YT, Scott WK, Gilbert JR, Haines JL, Pericak-Vance MA. Comparing age-related macular degeneration phenotype in probands from singleton and multiplex families. American Journal of Ophthalmology. 139: 820-5. PMID 15860286 DOI: 10.1016/J.Ajo.2004.12.029  0.375
2005 Ashley-Koch AE, Shao Y, Rimmler JB, Gaskell PC, Welsh-Bohmer KA, Jackson CE, Scott WK, Haines JL, Pericak-Vance MA. An autosomal genomic screen for dementia in an extended Amish family. Neuroscience Letters. 379: 199-204. PMID 15843063 DOI: 10.1016/J.Neulet.2004.12.065  0.349
2005 Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA. Complement factor H variant increases the risk of age-related macular degeneration. Science (New York, N.Y.). 308: 419-21. PMID 15761120 DOI: 10.1126/Science.1110359  0.722
2005 McCauley JL, Li C, Jiang L, Olson LM, Crockett G, Gainer K, Folstein SE, Haines JL, Sutcliffe JS. Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates. Bmc Medical Genetics. 6: 1. PMID 15647115 DOI: 10.1186/1471-2350-6-1  0.319
2005 Skaar DA, Shao Y, Haines JL, Stenger JE, Jaworski J, Martin ER, DeLong GR, Moore JH, McCauley JL, Sutcliffe JS, Ashley-Koch AE, Cuccaro ML, Folstein SE, Gilbert JR, Pericak-Vance MA. Analysis of the RELN gene as a genetic risk factor for autism. Molecular Psychiatry. 10: 563-71. PMID 15558079 DOI: 10.1038/Sj.Mp.4001614  0.515
2004 Rabionet R, Jaworski JM, Ashley-Koch AE, Martin ER, Sutcliffe JS, Haines JL, Delong GR, Abramson RK, Wright HH, Cuccaro ML, Gilbert JR, Pericak-Vance MA. Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes. Neuroscience Letters. 372: 209-14. PMID 15542242 DOI: 10.1016/J.Neulet.2004.09.037  0.395
2004 Thornton-Wells TA, Moore JH, Haines JL. Genetics, statistics and human disease: analytical retooling for complexity. Trends in Genetics : Tig. 20: 640-7. PMID 15522460 DOI: 10.1016/J.Tig.2004.09.007  0.39
2004 Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, Schmidt S, Pericak-Vance MA, Barcellos LF, Lincoln RR, Oksenberg JR, Hauser SL, Clanet M, Brassat D, Edan G, et al. A second-generation genomic screen for multiple sclerosis. American Journal of Human Genetics. 75: 1070-8. PMID 15494893 DOI: 10.1086/426459  0.813
2004 Nicodemus KK, Stenger JE, Schmechel DE, Welsh-Bohmer KA, Saunders AM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA, Martin ER. Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. Neurogenetics. 5: 201-8. PMID 15455263 DOI: 10.1007/S10048-004-0189-9  0.46
2004 McCauley JL, Olson LM, Delahanty R, Amin T, Nurmi EL, Organ EL, Jacobs MM, Folstein SE, Haines JL, Sutcliffe JS. A linkage disequilibrium map of the 1-Mb 15q12 GABA(A) receptor subunit cluster and association to autism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 131: 51-9. PMID 15389768 DOI: 10.1002/Ajmg.B.30038  0.337
2004 Hauser ER, Crossman DC, Granger CB, Haines JL, Jones CJ, Mooser V, McAdam B, Winkelmann BR, Wiseman AH, Muhlestein JB, Bartel AG, Dennis CA, Dowdy E, Estabrooks S, Eggleston K, et al. A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. American Journal of Human Genetics. 75: 436-47. PMID 15272420 DOI: 10.1086/423900  0.303
2004 Sawcer SJ, Maranian M, Singlehurst S, Yeo T, Compston A, Daly MJ, De Jager PL, Gabriel S, Hafler DA, Ivinson AJ, Lander ES, Rioux JD, Walsh E, Gregory SG, Schmidt S, ... ... Haines JL, et al. Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping. Human Molecular Genetics. 13: 1943-9. PMID 15238506 DOI: 10.1093/Hmg/Ddh202  0.794
2004 Schmidt S, Scott WK, Postel EA, Agarwal A, Hauser ER, De La Paz MA, Gilbert JR, Weeks DE, Gorin MB, Haines JL, Pericak-Vance MA. Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12. Bmc Genetics. 5: 18. PMID 15238159 DOI: 10.1186/1471-2156-5-18  0.457
2004 Barcellos LF, Begovich AB, Reynolds RL, Caillier SJ, Brassat D, Schmidt S, Grams SE, Walker K, Steiner LL, Cree BA, Stillman A, Lincoln RR, Pericak-Vance MA, Haines JL, Erlich HA, et al. Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. Annals of Neurology. 55: 793-800. PMID 15174013 DOI: 10.1002/Ana.20092  0.381
2004 Weeks DE, Conley YP, Tsai HJ, Mah TS, Schmidt S, Postel EA, Agarwal A, Haines JL, Pericak-Vance MA, Rosenfeld PJ, Paul TO, Eller AW, Morse LS, Dailey JP, Ferrell RE, et al. Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions. American Journal of Human Genetics. 75: 174-89. PMID 15168325 DOI: 10.1086/422476  0.372
2004 Hutcheson HB, Olson LM, Bradford Y, Folstein SE, Santangelo SL, Sutcliffe JS, Haines JL. Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes. Bmc Medical Genetics. 5: 12. PMID 15128462 DOI: 10.1186/1471-2350-5-12  0.83
2004 McCauley JL, Olson LM, Dowd M, Amin T, Steele A, Blakely RD, Folstein SE, Haines JL, Sutcliffe JS. Linkage and association analysis at the serotonin transporter (SLC6A4) locus in a rigid-compulsive subset of autism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 127: 104-12. PMID 15108191 DOI: 10.1002/Ajmg.B.20151  0.385
2004 Kenealy SJ, Schmidt S, Agarwal A, Postel EA, De La Paz MA, Pericak-Vance MA, Haines JL. Linkage analysis for age-related macular degeneration supports a gene on chromosome 10q26. Molecular Vision. 10: 57-61. PMID 14758336 DOI: 10.1016/J.Ajo.2004.02.050  0.82
2004 Williams SM, Haines JL, Moore JH. The use of animal models in the study of complex disease: all else is never equal or why do so many human studies fail to replicate animal findings? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 26: 170-9. PMID 14745835 DOI: 10.1002/Bies.10401  0.392
2004 Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, ... ... Haines JL, et al. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. American Journal of Human Genetics. 74: 160-7. PMID 14669136 DOI: 10.1086/380997  0.326
2004 Pericak-Vance MA, Rimmler JB, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL, Cournu-Rebeix I, Azoulay-Cayla A, Lyon-Caen O, Fontaine B, Duhamel E, Coppin H, Brassat D, et al. Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study. Neurogenetics. 5: 45-8. PMID 14595552 DOI: 10.1007/S10048-003-0163-Y  0.337
2003 Kenealy SJ, Pericak-Vance MA, Haines JL. The genetic epidemiology of multiple sclerosis. Journal of Neuroimmunology. 143: 7-12. PMID 14575907 DOI: 10.1016/J.Jneuroim.2003.08.005  0.817
2003 Li YJ, Oliveira SA, Xu P, Martin ER, Stenger JE, Scherzer CR, Hauser MA, Scott WK, Small GW, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, ... ... Haines JL, et al. Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Human Molecular Genetics. 12: 3259-67. PMID 14570706 DOI: 10.1093/Hmg/Ddg357  0.304
2003 Scott WK, Hauser ER, Schmechel DE, Welsh-Bohmer KA, Small GW, Roses AD, Saunders AM, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22. American Journal of Human Genetics. 73: 1041-51. PMID 14564669 DOI: 10.1086/379083  0.428
2003 Sapp PC, Hosler BA, McKenna-Yasek D, Chin W, Gann A, Genise H, Gorenstein J, Huang M, Sailer W, Scheffler M, Valesky M, Haines JL, Pericak-Vance M, Siddique T, Horvitz HR, et al. Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis. American Journal of Human Genetics. 73: 397-403. PMID 12858291 DOI: 10.1086/377158  0.348
2003 Nurmi EL, Amin T, Olson LM, Jacobs MM, McCauley JL, Lam AY, Organ EL, Folstein SE, Haines JL, Sutcliffe JS. Dense linkage disequilibrium mapping in the 15q11-q13 maternal expression domain yields evidence for association in autism. Molecular Psychiatry. 8: 624-34, 570. PMID 12851639 DOI: 10.1038/Sj.Mp.4001283  0.371
2003 Schmidt S, Postel EA, Agarwal A, Allen IC, Walters SN, De la Paz MA, Scott WK, Haines JL, Pericak-Vance MA, Gilbert JR. Detailed analysis of allelic variation in the ABCA4 gene in age-related maculopathy. Investigative Ophthalmology & Visual Science. 44: 2868-75. PMID 12824224 DOI: 10.1167/Iovs.02-0957  0.361
2003 Thornton TA, Haines JL. PowerTrim: An automated decision support algorithm for preprocessing family-based genetic data. American Journal of Human Genetics. 72: 1280-1. PMID 12677557 DOI: 10.1086/374823  0.315
2003 van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, et al. Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. American Journal of Human Genetics. 72: 804-11. PMID 12618962 DOI: 10.1086/373937  0.334
2003 Hutcheson HB, Bradford Y, Folstein SE, Gardiner MB, Santangelo SL, Sutcliffe JS, Haines JL. Defining the autism minimum candidate gene region on chromosome 7. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 117: 90-6. PMID 12555242 DOI: 10.1002/Ajmg.B.10033  0.813
2002 Scott WK, Vance JM, Haines JL, Pericak-Vance MA. Linkage of Parkinsonism and Alzheimer's disease with Lewy body pathology to chromosome 12. Annals of Neurology. 52: 524; author reply 52. PMID 12325086 DOI: 10.1002/Ana.10330  0.328
2002 Haines JL, Bradford Y, Garcia ME, Reed AD, Neumeister E, Pericak-Vance MA, Rimmler JB, Menold MM, Martin ER, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL. Multiple susceptibility loci for multiple sclerosis. Human Molecular Genetics. 11: 2251-6. PMID 12217953 DOI: 10.1093/Hmg/11.19.2251  0.36
2002 Thomas AQ, Lane K, Phillips J, Prince M, Markin C, Speer M, Schwartz DA, Gaddipati R, Marney A, Johnson J, Roberts R, Haines J, Stahlman M, Loyd JE. Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred. American Journal of Respiratory and Critical Care Medicine. 165: 1322-8. PMID 11991887 DOI: 10.1164/Rccm.200112-123Oc  0.301
2002 Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA, Goetz CG, ... ... Haines JL, et al. Age at onset in two common neurodegenerative diseases is genetically controlled. American Journal of Human Genetics. 70: 985-93. PMID 11875758 DOI: 10.1086/339815  0.412
2002 Schmidt S, Barcellos LF, DeSombre K, Rimmler JB, Lincoln RR, Bucher P, Saunders AM, Lai E, Martin ER, Vance JM, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines JL. Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. American Journal of Human Genetics. 70: 708-17. PMID 11836653 DOI: 10.1086/339269  0.505
2002 Gao H, Boustany RM, Espinola JA, Cotman SL, Srinidhi L, Antonellis KA, Gillis T, Qin X, Liu S, Donahue LR, Bronson RT, Faust JR, Stout D, Haines JL, Lerner TJ, et al. Mutations in a novel CLN6-encoded transmembrane protein cause variant neuronal ceroid lipofuscinosis in man and mouse. American Journal of Human Genetics. 70: 324-35. PMID 11791207 DOI: 10.1086/338190  0.412
2001 Pericak-Vance MA, Rimmler JB, Martin ER, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Goodkin DE, Hauser SL. Linkage and association analysis of chromosome 19q13 in multiple sclerosis. Neurogenetics. 3: 195-201. PMID 11714099 DOI: 10.1007/S100480100119  0.488
2001 Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Goetz CG, ... ... Haines JL, et al. Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. Jama. 286: 2245-50. PMID 11710889 DOI: 10.1001/Jama.286.18.2245  0.33
2001 Nurmi EL, Bradford Y, Chen Y, Hall J, Arnone B, Gardiner MB, Hutcheson HB, Gilbert JR, Pericak-Vance MA, Copeland-Yates SA, Michaelis RC, Wassink TH, Santangelo SL, Sheffield VC, Piven J, ... ... Haines JL, et al. Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. Genomics. 77: 105-13. PMID 11543639 DOI: 10.1006/Geno.2001.6617  0.8
2001 Pericak-Vance MA, Rimmler JB, Saunders AM, Martin ER, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Goodkin DE, Hauser SL, Compston DAS, Sawcer SJ, Clayton D, Jones HB, et al. A meta-analysis of genomic screens in multiple sclerosis Multiple Sclerosis. 7: 3-11. PMID 11321191 DOI: 10.1191/135245801669625359  0.343
2000 Kunst CB, Messer L, Gordon J, Haines J, Patterson D. Genetic mapping of a mouse modifier gene that can prevent ALS onset Genomics. 70: 181-189. PMID 11112346 DOI: 10.1006/Geno.2000.6379  0.356
2000 Hosler BA, Siddique T, Sapp PC, Sailor W, Huang MC, Hossain A, Daube JR, Nance M, Fan C, Kaplan J, Hung WY, McKenna-Yasek D, Haines JL, Pericak-Vance MA, Horvitz HR, et al. Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22. Jama. 284: 1664-9. PMID 11015796 DOI: 10.1001/Jama.284.13.1664  0.307
2000 Barcellos LF, Schito AM, Rimmler JB, Vittinghoff E, Shih A, Lincoln R, Callier S, Elkins MK, Goodkin DE, Haines JL, Pericak-Vance MA, Hauser SL, Oksenberg JR. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group. Immunogenetics. 51: 281-8. PMID 10803840 DOI: 10.1007/S002510050621  0.353
2000 Wiggs JL, Allingham RR, Hossain A, Kern J, Auguste J, DelBono EA, Broomer B, Graham FL, Hauser M, Pericak-Vance M, Haines JL. Genome-wide scan for adult onset primary open angle glaucoma. Human Molecular Genetics. 9: 1109-17. PMID 10767336 DOI: 10.1093/Hmg/9.7.1109  0.378
2000 Scott WK, Grubber JM, Conneally PM, Small GW, Hulette CM, Rosenberg CK, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity. American Journal of Human Genetics. 66: 922-32. PMID 10712207 DOI: 10.1086/302828  0.442
1999 Haines JL, Pericak-Vance MA. Genetics of multiple sclerosis. Current Directions in Autoimmunity. 1: 273-88. PMID 11791446 DOI: 10.1159/000060491  0.363
1999 Garcia ME, Haines JL. Hunting genetic diseases: Exploring a multistage approach to identifying disease loci Genetic Epidemiology. 17. PMID 10597492 DOI: 10.1002/Gepi.1370170790  0.444
1999 Barrett S, Beck JC, Bernier R, Bisson E, Braun TA, Casavant TL, Childress D, Folstein SE, Garcia M, Gardiner MB, Gilman S, Haines JL, Hopkins K, Landa R, Meyer NH, et al. An autosomal genomic screen for autism. Collaborative linkage study of autism. American Journal of Medical Genetics. 88: 609-15. PMID 10581478 DOI: 10.1002/(SICI)1096-8628(19991215)88:6<609::AID-AJMG7>3.0.CO;2-L  0.318
1999 Scott WK, Yamaoka LH, Stajich JM, Scott BL, Vance JM, Roses AD, Pericak-Vance MA, Watts RL, Nance M, Hubble J, Koller W, Stern MB, Colcher A, Allen FH, Hiner BC, ... ... Haines JL, et al. The alpha-synuclein gene is not a major risk factor in familial Parkinson disease. Neurogenetics. 2: 191-2. PMID 10541595 DOI: 10.1007/S100480050083  0.331
1999 De La Paz MA, Guy VK, Abou-Donia S, Heinis R, Bracken B, Vance JM, Gilbert JR, Gass JD, Haines JL, Pericak-Vance MA. Analysis of the Stargardt disease gene (ABCR) in age-related macular degeneration. Ophthalmology. 106: 1531-6. PMID 10442900 DOI: 10.1016/S0161-6420(99)90449-9  0.462
1999 Scott WK, Grubber JM, Abou-Donia SM, Church TD, Saunders AM, Roses AD, Pericak-Vance MA, Conneally PM, Small GW, Haines JL. Further evidence linking late-onset Alzheimer disease with chromosome 12. Jama. 281: 513-4. PMID 10022104 DOI: 10.1001/Jama.281.6.513  0.35
1998 Scott WK, Yamaoka LH, Bass MP, Gaskell PC, Conneally PM, Small GW, Farrer LA, Auerbach SA, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. Neurogenetics. 1: 179-83. PMID 10737120 DOI: 10.1007/S100480050026  0.323
1998 Hosler BA, Sapp PC, Berger R, O'Neill G, Bejaoui K, Hamida MB, Hentati F, Chin W, McKenna-Yasek D, Haines JL, Patterson D, Horvitz HR, Brown RH, Day CB. Refined mapping and characterization of the recessive familial amyotrophic lateral sclerosis locus (ALS2) on chromosome 2q33. Neurogenetics. 2: 34-42. PMID 9933298 DOI: 10.1007/S100480050049  0.447
1998 Pericak-Vance MA, Bass ML, Yamaoka LH, Gaskell PC, Scott WK, Terwedow HA, Menold MM, Conneally PM, Small GW, Saunders AM, Roses AD, Haines JL. Complete genomic screen in late-onset familial Alzheimer's disease. Neurobiology of Aging. 19: S39-42. PMID 9562466 DOI: 10.1016/S0197-4580(98)00037-2  0.351
1998 De la Paz MA, Pericak-Vance MA, Haines JL, Seddon JM. Phenotypic heterogeneity in families with age-related macular degeneration. American Journal of Ophthalmology. 124: 331-43. PMID 9439359 DOI: 10.1016/S0002-9394(14)70825-6  0.322
1998 De La Paz MA, Pericak-Vance MA, Lennon F, Haines JL, Seddon JM. Exclusion of TIMP3 as a Candidate Locus in Age-related Macular Degeneration Retina. 18: 190. DOI: 10.1097/00006982-199818020-00025  0.301
1997 Pericak-Vance MA, Bass MP, Yamaoka LH, Gaskell PC, Scott WK, Terwedow HA, Menold MM, Conneally PM, Small GW, Vance JM, Saunders AM, Roses AD, Haines JL. Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12. Jama. 278: 1237-41. PMID 9333264 DOI: 10.1001/Jama.1997.03550150041033  0.368
1997 Scott WK, Yamaoka LH, Locke PA, Rosi BL, Gaskell PC, Saunders AM, Conneally PM, Small GW, Farrer LA, Growdon JH, Roses AD, Pericak-Vance MA, Haines JL. No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease. Genetic Epidemiology. 14: 307-15. PMID 9181359 DOI: 10.1002/(Sici)1098-2272(1997)14:3<307::Aid-Gepi8>3.0.Co;2-1  0.318
1996 Haines JL, Ter-Minassian M, Bazyk A, Gusella JF, Kim DJ, Terwedow H, Pericak-Vance MA, Rimmler JB, Haynes CS, Roses AD, Lee A, Shaner B, Menold M, Seboun E, Fitoussi RP, et al. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group. Nature Genetics. 13: 469-71. PMID 8696344 DOI: 10.1038/Ng0896-469  0.397
1993 Blumenfeld A, Slaugenhaupt SA, Axelrod FB, Lucente DE, Maayan C, Liebert CB, Ozelius LJ, Trofatter JA, Haines JL, Breakefield XO. Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis. Nature Genetics. 4: 160-4. PMID 8102296 DOI: 10.1038/ng0693-160  0.31
1991 Siddique T, Figlewicz DA, Pericak-Vance MA, Haines JL, Rouleau G, Jeffers AJ, Sapp P, Hung WY, Bebout J, McKenna-Yasek D. Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity. The New England Journal of Medicine. 324: 1381-4. PMID 2020294 DOI: 10.1056/Nejm199105163242001  0.324
1990 St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature. 347: 194-7. PMID 2395471 DOI: 10.1038/347194A0  0.347
1984 Haines JL, Schut LJ, Weitkamp LR, Thayer M, Anderson VE. Spinocerebellar ataxia in a large kindred: age at onset, reproduction, and genetic linkage studies. Neurology. 34: 1542-8. PMID 6504324 DOI: 10.1212/WNL.34.12.1542  0.306
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